Drosophila melanogaster

113 known processes

shrb (Dmel_CG8055)

shrub

(Aliases: Vps32,CG8055,vps32/snf7,ESCRT-III,vps32,Snf7/Vps32,Snf7,anon-WO0118547.180,Dmel\CG8055)

shrb biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
membrane budding GO:0006900 4 0.879
Yeast
vesicle organization GO:0016050 44 0.862
Yeast
single organism membrane budding GO:1902591 2 0.835
Yeast
endosomal transport GO:0016197 44 0.718
dendrite morphogenesis GO:0048813 199 0.573
vacuolar transport GO:0007034 13 0.509
Yeast
single organism cellular localization GO:1902580 180 0.498
Yeast
dendrite development GO:0016358 204 0.391
cytoplasmic transport GO:0016482 130 0.387
Yeast
negative regulation of response to stimulus GO:0048585 258 0.348
establishment of localization in cell GO:0051649 402 0.347
positive regulation of response to stimulus GO:0048584 323 0.340
purine ribonucleotide metabolic process GO:0009150 145 0.328
regulation of nervous system development GO:0051960 248 0.327
enzyme linked receptor protein signaling pathway GO:0007167 179 0.310
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.309
single organism intracellular transport GO:1902582 207 0.292
cell proliferation GO:0008283 299 0.276
epithelial cell differentiation GO:0030855 322 0.273
regulation of epidermal growth factor receptor signaling pathway GO:0042058 42 0.272
negative regulation of erbb signaling pathway GO:1901185 29 0.265
purine nucleoside metabolic process GO:0042278 127 0.260
epithelial cell development GO:0002064 274 0.256
membrane organization GO:0061024 112 0.236
Yeast
purine nucleoside triphosphate catabolic process GO:0009146 108 0.231
intracellular signal transduction GO:0035556 300 0.230
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.222
regulation of cell morphogenesis GO:0022604 163 0.218
intracellular transport GO:0046907 228 0.215
catabolic process GO:0009056 409 0.215
single organism membrane organization GO:0044802 93 0.214
Yeast
glycosyl compound metabolic process GO:1901657 127 0.214
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.205
chemotaxis GO:0006935 249 0.204
nucleotide catabolic process GO:0009166 109 0.198
axonogenesis GO:0007409 290 0.194
purine nucleoside catabolic process GO:0006152 112 0.189
localization of cell GO:0051674 257 0.186
nucleoside triphosphate metabolic process GO:0009141 120 0.186
cellular catabolic process GO:0044248 372 0.183
glycosyl compound catabolic process GO:1901658 112 0.182
positive regulation of nervous system development GO:0051962 69 0.179
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.178
actin cytoskeleton organization GO:0030036 206 0.173
interspecies interaction between organisms GO:0044419 16 0.170
ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway GO:0043162 8 0.165
regulation of notch signaling pathway GO:0008593 100 0.161
mitotic cell cycle checkpoint GO:0007093 88 0.160
positive regulation of developmental process GO:0051094 143 0.160
actin filament based process GO:0030029 220 0.160
protein localization GO:0008104 284 0.155
purine containing compound catabolic process GO:0072523 112 0.151
regulation of anatomical structure morphogenesis GO:0022603 242 0.147
regulation of epithelial cell proliferation GO:0050678 4 0.146
protein complex assembly GO:0006461 200 0.137
regulation of neurogenesis GO:0050767 158 0.136
cell migration GO:0016477 238 0.133
apoptotic process GO:0006915 159 0.131
positive regulation of intracellular signal transduction GO:1902533 116 0.128
adult behavior GO:0030534 137 0.124
ribonucleoside triphosphate catabolic process GO:0009203 108 0.121
vesicle mediated transport GO:0016192 381 0.120
Yeast Worm
purine nucleotide catabolic process GO:0006195 109 0.120
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.118
small molecule metabolic process GO:0044281 305 0.116
regulation of cell development GO:0060284 215 0.115
nucleobase containing small molecule metabolic process GO:0055086 174 0.113
purine nucleoside triphosphate metabolic process GO:0009144 119 0.113
regulation of localization GO:0032879 275 0.112
nucleobase containing compound catabolic process GO:0034655 165 0.110
ribonucleoside metabolic process GO:0009119 127 0.108
regulation of intracellular signal transduction GO:1902531 236 0.106
cell division GO:0051301 248 0.106
regulation of vesicle mediated transport GO:0060627 59 0.105
actin filament organization GO:0007015 126 0.104
nucleoside catabolic process GO:0009164 112 0.103
purine ribonucleoside catabolic process GO:0046130 112 0.103
regulation of cellular component biogenesis GO:0044087 201 0.102
protein modification process GO:0036211 438 0.100
gliogenesis GO:0042063 80 0.100
regulation of ras protein signal transduction GO:0046578 93 0.099
aromatic compound catabolic process GO:0019439 166 0.099
positive regulation of cell communication GO:0010647 250 0.097
regulation of response to stress GO:0080134 200 0.097
regulation of transport GO:0051049 181 0.097
wnt signaling pathway GO:0016055 98 0.095
negative regulation of signaling GO:0023057 219 0.094
establishment of protein localization GO:0045184 163 0.092
autophagy GO:0006914 108 0.092
ribonucleoside triphosphate metabolic process GO:0009199 119 0.091
negative regulation of signal transduction GO:0009968 206 0.090
purine nucleotide metabolic process GO:0006163 146 0.089
ribose phosphate metabolic process GO:0019693 145 0.084
regulation of protein complex assembly GO:0043254 42 0.084
purine ribonucleotide catabolic process GO:0009154 109 0.083
positive regulation of neurogenesis GO:0050769 41 0.083
positive regulation of cell migration GO:0030335 2 0.083
heterocycle catabolic process GO:0046700 166 0.082
regulation of neuron differentiation GO:0045664 103 0.080
negative regulation of growth of symbiont involved in interaction with host GO:0044146 9 0.080
head development GO:0060322 135 0.080
organophosphate metabolic process GO:0019637 195 0.079
cell adhesion GO:0007155 136 0.079
mesoderm development GO:0007498 78 0.078
oocyte fate determination GO:0030716 27 0.078
organic substance transport GO:0071702 257 0.077
regulation of endocytosis GO:0030100 37 0.077
negative regulation of cell communication GO:0010648 223 0.077
purine ribonucleoside metabolic process GO:0046128 127 0.076
organelle localization GO:0051640 148 0.076
modification dependent macromolecule catabolic process GO:0043632 79 0.075
ribonucleotide catabolic process GO:0009261 109 0.074
cellular macromolecule catabolic process GO:0044265 136 0.074
regulation of cell shape GO:0008360 113 0.073
ribonucleoside catabolic process GO:0042454 112 0.071
taxis GO:0042330 304 0.070
establishment of protein localization to organelle GO:0072594 62 0.069
organic cyclic compound catabolic process GO:1901361 168 0.069
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.068
protein polymerization GO:0051258 42 0.068
organophosphate catabolic process GO:0046434 112 0.068
epidermal growth factor receptor signaling pathway GO:0007173 58 0.068
regulation of multicellular organismal development GO:2000026 414 0.068
negative regulation of epidermal growth factor receptor signaling pathway GO:0042059 29 0.067
erbb signaling pathway GO:0038127 58 0.067
negative regulation of transcription dna templated GO:0045892 237 0.066
proteolysis GO:0006508 192 0.066
nucleoside phosphate metabolic process GO:0006753 162 0.066
positive regulation of cell motility GO:2000147 3 0.065
ras protein signal transduction GO:0007265 88 0.065
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.064
regulation of cytoskeleton organization GO:0051493 89 0.063
axon development GO:0061564 297 0.063
single organismal cell cell adhesion GO:0016337 45 0.062
nucleoside metabolic process GO:0009116 127 0.062
pseudocleavage involved in syncytial blastoderm formation GO:0030589 9 0.062
regulation of multi organism process GO:0043900 131 0.061
protein localization to organelle GO:0033365 82 0.060
regulation of synapse assembly GO:0051963 94 0.060
endocytosis GO:0006897 310 0.060
Worm
nucleoside triphosphate catabolic process GO:0009143 108 0.060
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.059
cell cycle checkpoint GO:0000075 95 0.059
regulation of cell projection organization GO:0031344 92 0.058
single organism membrane fusion GO:0044801 42 0.058
neuron projection guidance GO:0097485 241 0.058
regulation of organelle organization GO:0033043 196 0.057
maintenance of location GO:0051235 73 0.057
positive regulation of signaling GO:0023056 243 0.057
cellular nitrogen compound catabolic process GO:0044270 165 0.056
ribonucleotide metabolic process GO:0009259 145 0.056
regulation of protein polymerization GO:0032271 28 0.055
actin filament polymerization GO:0030041 27 0.055
regulation of cellular catabolic process GO:0031329 157 0.055
ovarian follicle cell development GO:0030707 248 0.055
membrane fusion GO:0061025 42 0.055
eye morphogenesis GO:0048592 260 0.054
nucleotide metabolic process GO:0009117 161 0.054
adult locomotory behavior GO:0008344 76 0.054
maintenance of location in cell GO:0051651 28 0.053
positive regulation of signal transduction GO:0009967 223 0.053
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.053
aging GO:0007568 143 0.052
Worm
organonitrogen compound metabolic process GO:1901564 318 0.052
nucleocytoplasmic transport GO:0006913 72 0.052
negative regulation of neuron death GO:1901215 18 0.051
negative regulation of cell cycle GO:0045786 116 0.051
ubiquitin dependent protein catabolic process GO:0006511 78 0.051
biological adhesion GO:0022610 138 0.050
regulation of cell differentiation GO:0045595 302 0.050
positive regulation of cell development GO:0010720 61 0.050
organelle fusion GO:0048284 46 0.050
early endosome to late endosome transport GO:0045022 3 0.049
positive regulation of cellular amine metabolic process GO:0033240 0 0.049
secretion GO:0046903 109 0.049
Worm
regulation of phosphate metabolic process GO:0019220 210 0.049
carbohydrate derivative catabolic process GO:1901136 118 0.049
dorsal ventral pattern formation GO:0009953 133 0.049
regulation of cellular amine metabolic process GO:0033238 3 0.048
growth GO:0040007 359 0.047
nuclear transport GO:0051169 72 0.047
positive regulation of transport GO:0051050 92 0.047
regulation of cellular amino acid metabolic process GO:0006521 0 0.047
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.046
female germ line cyst formation GO:0048135 42 0.046
programmed cell death GO:0012501 257 0.045
cell motility GO:0048870 251 0.045
protein transport GO:0015031 155 0.045
small gtpase mediated signal transduction GO:0007264 88 0.045
intracellular protein transport GO:0006886 104 0.044
collateral sprouting GO:0048668 3 0.044
cellular protein complex assembly GO:0043623 71 0.044
eye development GO:0001654 323 0.043
endosome transport via multivesicular body sorting pathway GO:0032509 12 0.043
posttranscriptional regulation of gene expression GO:0010608 145 0.043
positive regulation of rna biosynthetic process GO:1902680 266 0.043
pronuclear migration GO:0035046 4 0.042
regulation of apoptotic process GO:0042981 130 0.042
regulation of synapse organization GO:0050807 110 0.042
negative regulation of gene expression GO:0010629 387 0.041
regulation of cell death GO:0010941 173 0.041
axon guidance GO:0007411 233 0.041
death GO:0016265 284 0.041
positive regulation of tor signaling GO:0032008 13 0.041
determination of dorsal ventral asymmetry GO:0048262 3 0.040
positive regulation of exocytosis GO:0045921 4 0.040
transcription from rna polymerase ii promoter GO:0006366 368 0.040
cellular response to chemical stimulus GO:0070887 199 0.040
Yeast
purine ribonucleoside monophosphate metabolic process GO:0009167 50 0.040
organelle assembly GO:0070925 198 0.039
regulation of cellular localization GO:0060341 136 0.039
regulation of small gtpase mediated signal transduction GO:0051056 93 0.039
symbiosis encompassing mutualism through parasitism GO:0044403 16 0.038
regulation of response to external stimulus GO:0032101 115 0.038
establishment or maintenance of cell polarity GO:0007163 167 0.038
positive regulation of endocytosis GO:0045807 22 0.038
regulation of nucleotide catabolic process GO:0030811 48 0.038
negative regulation of cellular metabolic process GO:0031324 382 0.037
jak stat cascade GO:0007259 49 0.037
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 15 0.037
cellular protein localization GO:0034613 160 0.036
regulation of protein metabolic process GO:0051246 256 0.036
positive regulation of immune system process GO:0002684 68 0.036
nucleoside phosphate catabolic process GO:1901292 110 0.036
regulation of protein modification process GO:0031399 112 0.035
positive regulation of macromolecule metabolic process GO:0010604 405 0.035
protein complex biogenesis GO:0070271 201 0.035
negative regulation of apoptotic process GO:0043066 63 0.034
regulation of epithelial cell differentiation GO:0030856 4 0.034
regulation of actin cytoskeleton organization GO:0032956 42 0.034
regulation of catabolic process GO:0009894 170 0.034
response to abiotic stimulus GO:0009628 341 0.033
Yeast
viral life cycle GO:0019058 7 0.033
negative regulation of nucleic acid templated transcription GO:1903507 240 0.033
negative regulation of intracellular signal transduction GO:1902532 57 0.033
positive regulation of behavior GO:0048520 19 0.033
translation GO:0006412 69 0.032
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.032
phagocytosis GO:0006909 215 0.032
mitotic dna damage checkpoint GO:0044773 74 0.032
gtp catabolic process GO:0006184 72 0.032
chemical homeostasis GO:0048878 92 0.032
single organism catabolic process GO:0044712 228 0.032
regulation of cellular component size GO:0032535 98 0.031
somatic muscle development GO:0007525 66 0.031
protein ubiquitination GO:0016567 70 0.031
protein localization to golgi apparatus GO:0034067 3 0.031
negative regulation of developmental process GO:0051093 201 0.030
respiratory system development GO:0060541 213 0.030
exocytosis GO:0006887 28 0.030
establishment of organelle localization GO:0051656 122 0.030
protein modification by small protein conjugation GO:0032446 79 0.029
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.029
macromolecular complex assembly GO:0065003 256 0.029
negative regulation of growth GO:0045926 84 0.029
regulation of cellular ketone metabolic process GO:0010565 3 0.029
mesenchymal cell differentiation GO:0048762 1 0.029
determination of adult lifespan GO:0008340 137 0.029
Worm
cellular macromolecular complex assembly GO:0034622 153 0.028
gtp metabolic process GO:0046039 72 0.028
cortical actin cytoskeleton organization GO:0030866 24 0.028
negative regulation of biosynthetic process GO:0009890 277 0.028
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.028
positive regulation of cellular component organization GO:0051130 156 0.028
autophagic vacuole fusion GO:0000046 15 0.028
developmental maturation GO:0021700 172 0.028
digestive system development GO:0055123 149 0.028
cellular response to organic substance GO:0071310 132 0.028
protein targeting GO:0006605 64 0.028
regulation of axonogenesis GO:0050770 32 0.028
regulation of autophagy GO:0010506 62 0.027
regulation of cellular response to stress GO:0080135 89 0.027
peptidyl tyrosine modification GO:0018212 24 0.027
cell fate specification GO:0001708 71 0.027
positive regulation of multicellular organismal process GO:0051240 143 0.027
establishment of glial blood brain barrier GO:0060857 14 0.027
body morphogenesis GO:0010171 2 0.027
regulation of cell proliferation GO:0042127 163 0.027
regulation of dendrite morphogenesis GO:0048814 28 0.027
multicellular organismal aging GO:0010259 140 0.027
Worm
positive regulation of phosphate metabolic process GO:0045937 139 0.027
cellular protein catabolic process GO:0044257 83 0.026
regulation of cell adhesion GO:0030155 27 0.026
regulation of immune system process GO:0002682 176 0.026
regulation of hydrolase activity GO:0051336 97 0.026
positive regulation of cellular catabolic process GO:0031331 95 0.026
positive regulation of transcription dna templated GO:0045893 266 0.026
purine containing compound metabolic process GO:0072521 155 0.026
organonitrogen compound catabolic process GO:1901565 128 0.026
imaginal disc fusion GO:0046528 19 0.026
protein modification by small protein conjugation or removal GO:0070647 106 0.026
carbohydrate derivative metabolic process GO:1901135 217 0.025
response to wounding GO:0009611 94 0.025
single organism cell adhesion GO:0098602 47 0.025
sensory organ morphogenesis GO:0090596 260 0.025
inositol lipid mediated signaling GO:0048017 4 0.025
phosphorylation GO:0016310 294 0.025
autophagic vacuole assembly GO:0000045 2 0.025
response to biotic stimulus GO:0009607 294 0.024
positive regulation of protein complex assembly GO:0031334 22 0.024
regulation of cytoplasmic transport GO:1903649 47 0.024
regulation of secretion by cell GO:1903530 39 0.024
regulation of nucleotide metabolic process GO:0006140 62 0.024
gland development GO:0048732 191 0.024
oocyte nucleus localization involved in oocyte dorsal ventral axis specification GO:0051663 12 0.024
regulation of catalytic activity GO:0050790 185 0.024
maintenance of protein location GO:0045185 28 0.024
regulation of lipid kinase activity GO:0043550 2 0.023
response to carbon dioxide GO:0010037 4 0.023
establishment of oocyte nucleus localization involved in oocyte dorsal ventral axis specification GO:0030722 6 0.023
cell growth GO:0016049 108 0.023
positive regulation of rna metabolic process GO:0051254 271 0.023
regulation of actin filament length GO:0030832 27 0.023
positive regulation of phosphorus metabolic process GO:0010562 139 0.023
positive regulation of cell differentiation GO:0045597 64 0.023
dorsal closure spreading of leading edge cells GO:0007395 4 0.023
epithelial cell morphogenesis involved in gastrulation GO:0003381 7 0.023
regulation of actin filament polymerization GO:0030833 25 0.023
regulation of developmental growth GO:0048638 174 0.023
notch signaling pathway GO:0007219 120 0.023
germarium derived female germ line cyst formation GO:0030727 42 0.022
negative regulation of rna metabolic process GO:0051253 251 0.022
amine metabolic process GO:0009308 12 0.022
phagocytosis engulfment GO:0006911 11 0.022
tissue morphogenesis GO:0048729 297 0.022
regulation of rho gtpase activity GO:0032319 20 0.022
positive regulation of nucleic acid templated transcription GO:1903508 266 0.022
wound healing GO:0042060 75 0.022
regulation of microtubule cytoskeleton organization GO:0070507 41 0.021
columnar cuboidal epithelial cell development GO:0002066 249 0.021
negative regulation of epithelial cell proliferation GO:0050680 4 0.021
organic substance catabolic process GO:1901575 308 0.021
regulation of secretion GO:0051046 44 0.021
regulation of actin polymerization or depolymerization GO:0008064 27 0.021
positive regulation of cytoskeleton organization GO:0051495 21 0.020
molting cycle GO:0042303 56 0.020
Worm
negative regulation of cellular component organization GO:0051129 108 0.020
regulation of erbb signaling pathway GO:1901184 42 0.020
positive regulation of cellular protein metabolic process GO:0032270 118 0.020
regulation of canonical wnt signaling pathway GO:0060828 15 0.020
positive regulation of secretion GO:0051047 22 0.020
morphogenesis of embryonic epithelium GO:0016331 94 0.020
salivary gland development GO:0007431 162 0.020
stem cell proliferation GO:0072089 88 0.020
phagolysosome assembly GO:0001845 2 0.020
positive regulation of purine nucleotide metabolic process GO:1900544 55 0.020
regulation of cell cycle process GO:0010564 181 0.020
camera type eye development GO:0043010 4 0.020
forebrain development GO:0030900 2 0.019
regulation of neuron apoptotic process GO:0043523 16 0.019
neural precursor cell proliferation GO:0061351 75 0.019
embryonic hemopoiesis GO:0035162 26 0.019
regulation of cellular protein metabolic process GO:0032268 243 0.019
positive regulation of dendrite development GO:1900006 9 0.019
negative regulation of mitotic cell cycle GO:0045930 109 0.019
chaeta development GO:0022416 97 0.019
imaginal disc derived wing morphogenesis GO:0007476 337 0.019
regulation of microtubule based process GO:0032886 49 0.019
growth of symbiont involved in interaction with host GO:0044116 9 0.019
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.019
regulation of phosphorus metabolic process GO:0051174 210 0.019
regulation of mitotic cell cycle phase transition GO:1901990 130 0.019
regulation of neuron projection development GO:0010975 69 0.019
tor signaling GO:0031929 32 0.019
negative regulation of rna biosynthetic process GO:1902679 240 0.019
defense response GO:0006952 300 0.019
positive regulation of nucleoside metabolic process GO:0045979 47 0.019
apical constriction GO:0003383 18 0.018
mapk cascade GO:0000165 107 0.018
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 4 0.018
activation of cysteine type endopeptidase activity GO:0097202 17 0.018
negative regulation of cell cycle phase transition GO:1901988 103 0.018
positive regulation of ras gtpase activity GO:0032320 36 0.018
cell projection assembly GO:0030031 94 0.018
kidney morphogenesis GO:0060993 3 0.018
cellular ketone metabolic process GO:0042180 24 0.018
wing disc morphogenesis GO:0007472 344 0.018
cell death GO:0008219 279 0.018
actin filament bundle organization GO:0061572 28 0.018
negative regulation of notch signaling pathway GO:0045746 41 0.018
purine nucleoside monophosphate metabolic process GO:0009126 50 0.018
cell cell junction organization GO:0045216 55 0.018
appendage morphogenesis GO:0035107 397 0.018
positive regulation of biosynthetic process GO:0009891 316 0.018
phagosome acidification GO:0090383 1 0.017
neuron apoptotic process GO:0051402 17 0.017
immune response GO:0006955 246 0.017
positive regulation of protein modification process GO:0031401 58 0.017
regulation of purine nucleotide metabolic process GO:1900542 62 0.017
regulation of jnk cascade GO:0046328 40 0.017
mitotic spindle organization GO:0007052 220 0.017
nuclear import GO:0051170 51 0.017
intracellular ph reduction GO:0051452 7 0.017
cellular protein modification process GO:0006464 438 0.017
regulation of purine nucleotide catabolic process GO:0033121 48 0.017
dna damage checkpoint GO:0000077 78 0.016
establishment or maintenance of cytoskeleton polarity GO:0030952 44 0.016
immune system development GO:0002520 57 0.016
positive regulation of developmental growth GO:0048639 62 0.016
purine nucleoside monophosphate catabolic process GO:0009128 38 0.016
cytoplasmic microtubule organization GO:0031122 22 0.016
regulation of cell cycle GO:0051726 291 0.016
cellular amino acid metabolic process GO:0006520 61 0.016
negative regulation of cellular biosynthetic process GO:0031327 277 0.016
connective tissue development GO:0061448 3 0.016
negative regulation of cell differentiation GO:0045596 143 0.016
limb morphogenesis GO:0035108 1 0.016
larval development GO:0002164 104 0.016
Worm
positive regulation of protein polymerization GO:0032273 14 0.016
lipid localization GO:0010876 54 0.016
cellular response to dna damage stimulus GO:0006974 223 0.016
meiotic cytokinesis GO:0033206 33 0.016
open tracheal system development GO:0007424 204 0.015
regulation of gtpase activity GO:0043087 44 0.015
developmental growth GO:0048589 280 0.015
positive regulation of response to external stimulus GO:0032103 44 0.015
regulation of protein localization GO:0032880 76 0.015
positive regulation of cellular biosynthetic process GO:0031328 316 0.015
gland morphogenesis GO:0022612 145 0.015
positive regulation of gene expression GO:0010628 290 0.015
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.015
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.015
organelle fission GO:0048285 340 0.015
positive regulation of lipid metabolic process GO:0045834 4 0.015
positive regulation of phagocytosis GO:0050766 3 0.015
actin cytoskeleton reorganization GO:0031532 22 0.015
bmp signaling pathway GO:0030509 27 0.014
positive regulation of cell adhesion GO:0045785 10 0.014
hindbrain development GO:0030902 2 0.014
regulation of wound healing GO:0061041 13 0.014
negative regulation of cell proliferation GO:0008285 69 0.014
response to endogenous stimulus GO:0009719 119 0.014
positive regulation of axonogenesis GO:0050772 2 0.014
negative regulation of cell cycle process GO:0010948 109 0.014
negative regulation of cell development GO:0010721 62 0.014
negative regulation of phosphorus metabolic process GO:0010563 45 0.014
response to external biotic stimulus GO:0043207 293 0.014
morphogenesis of an epithelium GO:0002009 276 0.014
regulation of transferase activity GO:0051338 58 0.014
regulation of phosphorylation GO:0042325 147 0.014
signal transduction by phosphorylation GO:0023014 107 0.014
negative regulation of phosphatidylinositol 3 kinase signaling GO:0014067 4 0.014
centrosome duplication GO:0051298 121 0.014
cellular macromolecule localization GO:0070727 220 0.014
cellular amine metabolic process GO:0044106 12 0.014
secretion by cell GO:0032940 101 0.014
Worm
positive regulation of purine nucleotide catabolic process GO:0033123 46 0.014
cortical cytoskeleton organization GO:0030865 29 0.013
cellular component disassembly GO:0022411 46 0.013
positive regulation of protein metabolic process GO:0051247 128 0.013
phosphatidylinositol 3 kinase signaling GO:0014065 4 0.013
negative regulation of cell death GO:0060548 81 0.013
regulation of gliogenesis GO:0014013 11 0.013
nucleoside monophosphate catabolic process GO:0009125 39 0.013
positive regulation of neuron differentiation GO:0045666 26 0.013
endosomal vesicle fusion GO:0034058 4 0.013
cytokinesis GO:0000910 90 0.013
vesicle fusion GO:0006906 19 0.013
germarium derived egg chamber formation GO:0007293 101 0.013
positive regulation of nucleotide catabolic process GO:0030813 46 0.013
regulation of nucleoside metabolic process GO:0009118 50 0.013
protein catabolic process GO:0030163 101 0.013
response to topologically incorrect protein GO:0035966 10 0.013
positive regulation of secretion by cell GO:1903532 20 0.013
regulation of synapse structure and activity GO:0050803 128 0.012
positive regulation of catalytic activity GO:0043085 118 0.012
mesenchymal cell development GO:0014031 1 0.012
microtubule organizing center organization GO:0031023 168 0.012
activation of rac gtpase activity GO:0032863 3 0.012
positive regulation of protein kinase activity GO:0045860 25 0.012
compound eye morphogenesis GO:0001745 249 0.012
lipid metabolic process GO:0006629 121 0.012
cellular response to growth factor stimulus GO:0071363 30 0.012
protein import into nucleus GO:0006606 51 0.012
regulation of mitotic cell cycle GO:0007346 190 0.012
neuron death GO:0070997 27 0.012
positive regulation of actin filament polymerization GO:0030838 11 0.012
regulation of phosphatidylinositol 3 kinase signaling GO:0014066 4 0.012
maintenance of protein location in cell GO:0032507 26 0.012
micropyle formation GO:0046844 4 0.012
exocrine system development GO:0035272 162 0.012
regulation of glial cell proliferation GO:0060251 11 0.012
ameboidal type cell migration GO:0001667 151 0.012
regulation of protein transport GO:0051223 57 0.012
negative regulation of programmed cell death GO:0043069 72 0.012
negative regulation of protein complex disassembly GO:0043242 23 0.012
germ line cyst formation GO:0048134 44 0.012
single organism behavior GO:0044708 391 0.012
protein targeting to nucleus GO:0044744 51 0.012
microtubule based movement GO:0007018 51 0.012
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 41 0.012
regulation of stress activated protein kinase signaling cascade GO:0070302 42 0.012
regulation of behavior GO:0050795 75 0.012
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 3 0.012

shrb disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.151
musculoskeletal system disease DOID:17 0 0.036
nervous system disease DOID:863 0 0.022
muscular disease DOID:0080000 0 0.020
muscle tissue disease DOID:66 0 0.020