Drosophila melanogaster

20 known processes

alc (Dmel_CG8057)

alicorn

(Aliases: CG8057,l(2)45Ad,8057,betaAMPK,FBgn0033383,Dmel\CG8057)

alc biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
negative regulation of signaling GO:0023057 219 0.187
organic acid metabolic process GO:0006082 103 0.162
intracellular signal transduction GO:0035556 300 0.147
positive regulation of response to stimulus GO:0048584 323 0.146
negative regulation of cell communication GO:0010648 223 0.146
wing disc morphogenesis GO:0007472 344 0.120
enzyme linked receptor protein signaling pathway GO:0007167 179 0.117
post embryonic appendage morphogenesis GO:0035120 385 0.113
negative regulation of response to stimulus GO:0048585 258 0.107
oxoacid metabolic process GO:0043436 103 0.101
small molecule metabolic process GO:0044281 305 0.100
negative regulation of signal transduction GO:0009968 206 0.100
carboxylic acid metabolic process GO:0019752 92 0.099
response to nutrient levels GO:0031667 114 0.088
positive regulation of macromolecule metabolic process GO:0010604 405 0.086
positive regulation of cell communication GO:0010647 250 0.086
positive regulation of signaling GO:0023056 243 0.080
imaginal disc derived appendage morphogenesis GO:0035114 395 0.079
negative regulation of gene expression GO:0010629 387 0.077
tube development GO:0035295 244 0.074
amine metabolic process GO:0009308 12 0.070
centrosome cycle GO:0007098 137 0.068
positive regulation of signal transduction GO:0009967 223 0.068
organonitrogen compound metabolic process GO:1901564 318 0.061
growth GO:0040007 359 0.060
homeostatic process GO:0042592 199 0.060
developmental programmed cell death GO:0010623 138 0.060
appendage development GO:0048736 401 0.058
regulation of cell cycle GO:0051726 291 0.058
centrosome duplication GO:0051298 121 0.058
acyl coa metabolic process GO:0006637 3 0.056
metal ion homeostasis GO:0055065 44 0.056
imaginal disc derived wing morphogenesis GO:0007476 337 0.055
regulation of cellular ketone metabolic process GO:0010565 3 0.054
single organism catabolic process GO:0044712 228 0.052
regulation of multicellular organismal development GO:2000026 414 0.051
cellular ketone metabolic process GO:0042180 24 0.051
microtubule organizing center organization GO:0031023 168 0.051
imaginal disc derived appendage development GO:0048737 399 0.050
catabolic process GO:0009056 409 0.049
single organism biosynthetic process GO:0044711 206 0.049
negative regulation of developmental process GO:0051093 201 0.048
regulation of response to stress GO:0080134 200 0.047
centrosome organization GO:0051297 163 0.045
mitotic cytokinesis GO:0000281 50 0.045
macromolecular complex assembly GO:0065003 256 0.044
cellular amine metabolic process GO:0044106 12 0.043
organic substance catabolic process GO:1901575 308 0.042
phosphorylation GO:0016310 294 0.042
cellular catabolic process GO:0044248 372 0.042
cellular amino acid metabolic process GO:0006520 61 0.042
regionalization GO:0003002 416 0.040
posttranscriptional regulation of gene expression GO:0010608 145 0.040
dorsal ventral pattern formation GO:0009953 133 0.038
negative regulation of cellular metabolic process GO:0031324 382 0.038
response to organic substance GO:0010033 284 0.037
protein complex biogenesis GO:0070271 201 0.036
single organism cell adhesion GO:0098602 47 0.036
small molecule biosynthetic process GO:0044283 37 0.034
vesicle mediated transport GO:0016192 381 0.034
proteolysis GO:0006508 192 0.033
lipid metabolic process GO:0006629 121 0.033
ion homeostasis GO:0050801 55 0.033
regulation of anatomical structure size GO:0090066 163 0.033
regulation of phosphate metabolic process GO:0019220 210 0.032
regulation of mitotic cell cycle GO:0007346 190 0.032
gland development GO:0048732 191 0.032
imaginal disc derived wing vein specification GO:0007474 48 0.032
positive regulation of cellular biosynthetic process GO:0031328 316 0.031
regulation of phosphorus metabolic process GO:0051174 210 0.031
morphogenesis of an epithelium GO:0002009 276 0.031
negative regulation of cell cycle GO:0045786 116 0.031
developmental growth GO:0048589 280 0.031
regulation of cellular amine metabolic process GO:0033238 3 0.030
chemical homeostasis GO:0048878 92 0.030
nucleoside triphosphate metabolic process GO:0009141 120 0.030
digestive tract morphogenesis GO:0048546 127 0.029
regulation of cell differentiation GO:0045595 302 0.029
connective tissue development GO:0061448 3 0.029
response to endogenous stimulus GO:0009719 119 0.029
regulation of intracellular signal transduction GO:1902531 236 0.028
negative regulation of cell differentiation GO:0045596 143 0.028
monocarboxylic acid metabolic process GO:0032787 29 0.027
cellular response to organic substance GO:0071310 132 0.027
immune system process GO:0002376 347 0.027
taxis GO:0042330 304 0.027
regulation of cellular catabolic process GO:0031329 157 0.027
tube morphogenesis GO:0035239 191 0.026
cellular chemical homeostasis GO:0055082 40 0.026
programmed cell death GO:0012501 257 0.026
protein modification process GO:0036211 438 0.025
regulation of protein metabolic process GO:0051246 256 0.025
regulation of cellular amino acid metabolic process GO:0006521 0 0.025
epithelial cell differentiation GO:0030855 322 0.025
cellular response to chemical stimulus GO:0070887 199 0.024
positive regulation of wnt signaling pathway GO:0030177 25 0.024
male gamete generation GO:0048232 201 0.024
regulation of mapk cascade GO:0043408 92 0.024
organelle assembly GO:0070925 198 0.024
regulation of tube size GO:0035150 46 0.024
steroid catabolic process GO:0006706 1 0.024
appendage morphogenesis GO:0035107 397 0.024
fatty acid metabolic process GO:0006631 20 0.024
cell proliferation GO:0008283 299 0.024
cellular protein modification process GO:0006464 438 0.023
regulation of notch signaling pathway GO:0008593 100 0.023
salivary gland morphogenesis GO:0007435 145 0.023
ras protein signal transduction GO:0007265 88 0.023
positive regulation of gene expression GO:0010628 290 0.023
kidney development GO:0001822 3 0.022
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.022
lipid catabolic process GO:0016042 21 0.022
response to extracellular stimulus GO:0009991 116 0.022
cellular response to starvation GO:0009267 61 0.022
small gtpase mediated signal transduction GO:0007264 88 0.022
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.022
ribonucleotide metabolic process GO:0009259 145 0.022
cellular component assembly involved in morphogenesis GO:0010927 151 0.022
gene silencing by mirna GO:0035195 22 0.021
synapse organization GO:0050808 196 0.021
body morphogenesis GO:0010171 2 0.021
positive regulation of nucleic acid templated transcription GO:1903508 266 0.021
cellular homeostasis GO:0019725 80 0.021
regulation of response to external stimulus GO:0032101 115 0.021
negative regulation of mitotic cell cycle GO:0045930 109 0.020
autophagy GO:0006914 108 0.020
chromatin organization GO:0006325 207 0.020
muscle structure development GO:0061061 224 0.020
single organismal cell cell adhesion GO:0016337 45 0.019
cytoskeleton dependent cytokinesis GO:0061640 81 0.019
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.019
cellular component disassembly GO:0022411 46 0.019
protein localization GO:0008104 284 0.019
regulation of organelle organization GO:0033043 196 0.019
ribose phosphate metabolic process GO:0019693 145 0.019
transcription from rna polymerase ii promoter GO:0006366 368 0.019
small molecule catabolic process GO:0044282 21 0.019
endocytosis GO:0006897 310 0.019
regulation of gene expression epigenetic GO:0040029 128 0.019
positive regulation of cellular amine metabolic process GO:0033240 0 0.019
nucleotide metabolic process GO:0009117 161 0.018
nuclear division GO:0000280 332 0.018
regulation of molecular function GO:0065009 217 0.018
forebrain development GO:0030900 2 0.018
response to oxygen containing compound GO:1901700 200 0.018
wnt signaling pathway GO:0016055 98 0.018
notch signaling pathway GO:0007219 120 0.018
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.018
endomembrane system organization GO:0010256 119 0.018
nucleoside phosphate metabolic process GO:0006753 162 0.018
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.018
salivary gland cell autophagic cell death GO:0035071 83 0.018
posttranscriptional gene silencing by rna GO:0035194 45 0.018
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 18 0.018
myotube cell development GO:0014904 3 0.018
histolysis GO:0007559 102 0.018
multi organism behavior GO:0051705 175 0.018
cellular nitrogen compound catabolic process GO:0044270 165 0.018
salivary gland development GO:0007431 162 0.018
response to temperature stimulus GO:0009266 106 0.018
organophosphate metabolic process GO:0019637 195 0.017
lipid biosynthetic process GO:0008610 46 0.017
protein complex assembly GO:0006461 200 0.017
organic cyclic compound catabolic process GO:1901361 168 0.017
dna metabolic process GO:0006259 227 0.017
phagocytosis GO:0006909 215 0.017
regulation of cell cycle phase transition GO:1901987 130 0.017
positive regulation of biosynthetic process GO:0009891 316 0.017
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.017
cell division GO:0051301 248 0.017
organic hydroxy compound metabolic process GO:1901615 83 0.016
digestive system development GO:0055123 149 0.016
salivary gland histolysis GO:0035070 88 0.016
purine containing compound metabolic process GO:0072521 155 0.016
negative regulation of cell proliferation GO:0008285 69 0.016
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.016
response to abiotic stimulus GO:0009628 341 0.016
mapk cascade GO:0000165 107 0.016
response to organophosphorus GO:0046683 2 0.016
positive regulation of transcription dna templated GO:0045893 266 0.016
cellular lipid metabolic process GO:0044255 83 0.016
regulation of phosphorylation GO:0042325 147 0.016
stress activated protein kinase signaling cascade GO:0031098 55 0.016
organic substance transport GO:0071702 257 0.016
nucleosome organization GO:0034728 59 0.015
lipid homeostasis GO:0055088 33 0.015
chromosome organization GO:0051276 360 0.015
negative regulation of intracellular signal transduction GO:1902532 57 0.015
regulation of catabolic process GO:0009894 170 0.015
regulation of catalytic activity GO:0050790 185 0.015
purine nucleotide metabolic process GO:0006163 146 0.015
purine ribonucleotide metabolic process GO:0009150 145 0.015
ubiquitin dependent protein catabolic process GO:0006511 78 0.015
regulation of cellular response to stress GO:0080135 89 0.015
gtp metabolic process GO:0046039 72 0.015
mitotic sister chromatid segregation GO:0000070 87 0.015
organelle fission GO:0048285 340 0.015
regulation of epithelial cell proliferation GO:0050678 4 0.015
mitotic spindle organization GO:0007052 220 0.015
macromolecule catabolic process GO:0009057 161 0.015
molting cycle GO:0042303 56 0.014
skeletal muscle fiber development GO:0048741 3 0.014
cellular transition metal ion homeostasis GO:0046916 9 0.014
mitochondrion organization GO:0007005 65 0.014
tissue death GO:0016271 102 0.014
gene silencing by rna GO:0031047 57 0.014
developmental maturation GO:0021700 172 0.014
sterol homeostasis GO:0055092 4 0.014
steroid biosynthetic process GO:0006694 16 0.014
protein transport GO:0015031 155 0.014
stress activated mapk cascade GO:0051403 52 0.014
purine nucleoside metabolic process GO:0042278 127 0.014
stem cell development GO:0048864 79 0.014
epithelial cell development GO:0002064 274 0.014
protein modification by small protein conjugation or removal GO:0070647 106 0.014
detection of stimulus GO:0051606 156 0.014
cilium morphogenesis GO:0060271 39 0.014
negative regulation of cellular protein metabolic process GO:0032269 85 0.014
cell growth GO:0016049 108 0.014
organonitrogen compound biosynthetic process GO:1901566 117 0.014
molting cycle chitin based cuticle GO:0007591 56 0.014
stem cell differentiation GO:0048863 117 0.014
regulation of steroid metabolic process GO:0019218 2 0.014
regulation of cellular protein metabolic process GO:0032268 243 0.013
negative regulation of multicellular organismal process GO:0051241 142 0.013
positive regulation of catalytic activity GO:0043085 118 0.013
negative regulation of cellular biosynthetic process GO:0031327 277 0.013
positive regulation of intracellular signal transduction GO:1902533 116 0.013
carbohydrate metabolic process GO:0005975 82 0.013
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 38 0.013
regulation of stress activated mapk cascade GO:0032872 41 0.013
tissue morphogenesis GO:0048729 297 0.013
response to lipopolysaccharide GO:0032496 4 0.013
dendrite development GO:0016358 204 0.013
biological adhesion GO:0022610 138 0.013
antimicrobial humoral response GO:0019730 99 0.013
response to inorganic substance GO:0010035 44 0.013
cell adhesion GO:0007155 136 0.013
nucleotide catabolic process GO:0009166 109 0.013
positive regulation of phosphate metabolic process GO:0045937 139 0.013
negative regulation of cell cycle process GO:0010948 109 0.013
synapse assembly GO:0007416 143 0.013
bmp signaling pathway GO:0030509 27 0.013
peptide metabolic process GO:0006518 80 0.013
sulfur compound metabolic process GO:0006790 59 0.013
regulation of hydrolase activity GO:0051336 97 0.013
anion homeostasis GO:0055081 3 0.013
somatic muscle development GO:0007525 66 0.013
response to hexose GO:0009746 3 0.013
organelle localization GO:0051640 148 0.013
response to starvation GO:0042594 97 0.013
positive regulation of rna biosynthetic process GO:1902680 266 0.013
regulation of defense response GO:0031347 102 0.013
circulatory system process GO:0003013 37 0.013
posttranscriptional gene silencing GO:0016441 46 0.013
oxidation reduction process GO:0055114 123 0.013
embryonic morphogenesis GO:0048598 206 0.013
autophagic cell death GO:0048102 83 0.013
embryonic development via the syncytial blastoderm GO:0001700 148 0.013
imaginal disc pattern formation GO:0007447 91 0.013
spindle organization GO:0007051 253 0.013
signal transduction by phosphorylation GO:0023014 107 0.013
brain development GO:0007420 120 0.012
protein ubiquitination GO:0016567 70 0.012
single organism carbohydrate metabolic process GO:0044723 72 0.012
single organism behavior GO:0044708 391 0.012
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.012
cellular response to endogenous stimulus GO:0071495 80 0.012
aromatic compound catabolic process GO:0019439 166 0.012
glycosyl compound metabolic process GO:1901657 127 0.012
cation homeostasis GO:0055080 51 0.012
regulation of wnt signaling pathway GO:0030111 68 0.012
regulation of immune response GO:0050776 118 0.012
regulation of system process GO:0044057 36 0.012
larval somatic muscle development GO:0007526 19 0.012
regulation of small gtpase mediated signal transduction GO:0051056 93 0.012
tricarboxylic acid metabolic process GO:0072350 1 0.012
regulation of anatomical structure morphogenesis GO:0022603 242 0.012
death GO:0016265 284 0.012
positive regulation of lipid metabolic process GO:0045834 4 0.012
regulation of mitotic cell cycle phase transition GO:1901990 130 0.012
regulation of cell proliferation GO:0042127 163 0.012
axis specification GO:0009798 167 0.012
positive regulation of phosphorus metabolic process GO:0010562 139 0.012
response to glucose GO:0009749 2 0.012
phototaxis GO:0042331 21 0.012
open tracheal system development GO:0007424 204 0.012
thioester metabolic process GO:0035383 3 0.012
carbohydrate derivative metabolic process GO:1901135 217 0.011
regulation of cell death GO:0010941 173 0.011
vesicle organization GO:0016050 44 0.011
chemosensory behavior GO:0007635 106 0.011
regulation of proteolysis GO:0030162 87 0.011
cellular protein localization GO:0034613 160 0.011
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.011
response to mercury ion GO:0046689 3 0.011
response to monosaccharide GO:0034284 4 0.011
positive regulation of protein metabolic process GO:0051247 128 0.011
dorsal ventral axis specification GO:0009950 66 0.011
establishment of localization in cell GO:0051649 402 0.011
regulation of nucleotide metabolic process GO:0006140 62 0.011
cellular macromolecular complex assembly GO:0034622 153 0.011
negative regulation of nervous system development GO:0051961 92 0.011
spermatogenesis GO:0007283 200 0.011
regulation of cell cycle process GO:0010564 181 0.011
regulation of synapse organization GO:0050807 110 0.011
cellular cation homeostasis GO:0030003 38 0.011
camera type eye development GO:0043010 4 0.011
cellular amide metabolic process GO:0043603 80 0.011
jnk cascade GO:0007254 50 0.011
regulation of localization GO:0032879 275 0.011
ribonucleoside metabolic process GO:0009119 127 0.011
cellular response to hormone stimulus GO:0032870 44 0.011
golgi organization GO:0007030 66 0.011
cellular response to dna damage stimulus GO:0006974 223 0.011
regulation of autophagy GO:0010506 62 0.011
peptidyl amino acid modification GO:0018193 105 0.011
response to other organism GO:0051707 293 0.011
acylglycerol biosynthetic process GO:0046463 2 0.011
heterocycle catabolic process GO:0046700 166 0.010
establishment of vesicle localization GO:0051650 51 0.010
dendrite morphogenesis GO:0048813 199 0.010
cell maturation GO:0048469 144 0.010
pigmentation GO:0043473 75 0.010
kidney morphogenesis GO:0060993 3 0.010
organonitrogen compound catabolic process GO:1901565 128 0.010
neuromuscular junction development GO:0007528 149 0.010
protein dna complex subunit organization GO:0071824 86 0.010
nucleus organization GO:0006997 45 0.010
regulation of purine nucleotide metabolic process GO:1900542 62 0.010
mesenchymal cell differentiation GO:0048762 1 0.010
cholesterol homeostasis GO:0042632 3 0.010
establishment of tissue polarity GO:0007164 87 0.010
transition metal ion homeostasis GO:0055076 17 0.010
regulation of ras protein signal transduction GO:0046578 93 0.010
cilium organization GO:0044782 41 0.010
purine nucleotide catabolic process GO:0006195 109 0.010
positive regulation of nucleotide catabolic process GO:0030813 46 0.010
glycerolipid metabolic process GO:0046486 34 0.010
protein modification by small protein conjugation GO:0032446 79 0.010
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.010
exocrine system development GO:0035272 162 0.010
meiotic cell cycle process GO:1903046 132 0.010
embryo development ending in birth or egg hatching GO:0009792 152 0.010
positive regulation of programmed cell death GO:0043068 62 0.010
ribonucleoside triphosphate metabolic process GO:0009199 119 0.010

alc disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.033
cardiovascular system disease DOID:1287 0 0.022
disease of metabolism DOID:0014667 0 0.018
inherited metabolic disorder DOID:655 0 0.014
musculoskeletal system disease DOID:17 0 0.013
nervous system disease DOID:863 0 0.012
bone disease DOID:0080001 0 0.012
connective tissue disease DOID:65 0 0.012
acquired metabolic disease DOID:0060158 0 0.012