Drosophila melanogaster

0 known processes

CG8223 (Dmel_CG8223)

CG8223 gene product from transcript CG8223-RA

(Aliases: Dmel\CG8223)

CG8223 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryo development ending in birth or egg hatching GO:0009792 152 0.246
negative regulation of cellular metabolic process GO:0031324 382 0.224
cellular response to dna damage stimulus GO:0006974 223 0.165
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.164
protein modification process GO:0036211 438 0.155
regulation of cell cycle phase transition GO:1901987 130 0.140
cell death GO:0008219 279 0.139
positive regulation of cellular biosynthetic process GO:0031328 316 0.135
chromosome organization GO:0051276 360 0.132
Human
catabolic process GO:0009056 409 0.128
mitotic cell cycle phase transition GO:0044772 138 0.127
regulation of proteasomal protein catabolic process GO:0061136 39 0.120
regionalization GO:0003002 416 0.120
negative regulation of cell cycle phase transition GO:1901988 103 0.115
mitotic nuclear division GO:0007067 213 0.115
positive regulation of cellular component biogenesis GO:0044089 80 0.111
male gamete generation GO:0048232 201 0.108
organelle fission GO:0048285 340 0.092
negative regulation of transcription dna templated GO:0045892 237 0.090
cellular protein modification process GO:0006464 438 0.088
embryonic morphogenesis GO:0048598 206 0.087
homeostatic process GO:0042592 199 0.086
ameboidal type cell migration GO:0001667 151 0.085
regulation of growth GO:0040008 233 0.084
positive regulation of nucleic acid templated transcription GO:1903508 266 0.081
negative regulation of gene expression GO:0010629 387 0.081
epithelial cell differentiation GO:0030855 322 0.079
cellular catabolic process GO:0044248 372 0.078
chromosome segregation GO:0007059 157 0.078
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 37 0.078
regulation of response to stress GO:0080134 200 0.077
dna templated transcription elongation GO:0006354 18 0.076
positive regulation of rna biosynthetic process GO:1902680 266 0.076
intracellular transport GO:0046907 228 0.076
macromolecule catabolic process GO:0009057 161 0.075
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.075
ubiquitin dependent protein catabolic process GO:0006511 78 0.074
regulation of cellular protein metabolic process GO:0032268 243 0.074
protein catabolic process GO:0030163 101 0.073
cytoplasmic transport GO:0016482 130 0.072
positive regulation of transcription dna templated GO:0045893 266 0.071
organelle assembly GO:0070925 198 0.069
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.069
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.069
regulation of protein metabolic process GO:0051246 256 0.067
macromolecular complex assembly GO:0065003 256 0.066
Human
phosphorylation GO:0016310 294 0.066
proteolysis GO:0006508 192 0.065
programmed cell death GO:0012501 257 0.064
body morphogenesis GO:0010171 2 0.064
dna integrity checkpoint GO:0031570 81 0.064
transcription from rna polymerase ii promoter GO:0006366 368 0.064
organic acid metabolic process GO:0006082 103 0.063
growth GO:0040007 359 0.063
positive regulation of macromolecule metabolic process GO:0010604 405 0.062
death GO:0016265 284 0.061
modification dependent macromolecule catabolic process GO:0043632 79 0.060
tube development GO:0035295 244 0.060
small molecule metabolic process GO:0044281 305 0.058
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.057
epithelial cell development GO:0002064 274 0.057
reproductive system development GO:0061458 74 0.055
positive regulation of rna metabolic process GO:0051254 271 0.055
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 23 0.054
regulation of mitotic cell cycle GO:0007346 190 0.054
cellular amide metabolic process GO:0043603 80 0.054
aging GO:0007568 143 0.053
chromosome separation GO:0051304 42 0.052
nuclear division GO:0000280 332 0.052
regulation of mitotic cell cycle phase transition GO:1901990 130 0.052
positive regulation of gene expression GO:0010628 290 0.052
spermatogenesis GO:0007283 200 0.052
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.052
regulation of proteolysis GO:0030162 87 0.051
negative regulation of cell communication GO:0010648 223 0.050
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.050
regulation of molecular function GO:0065009 217 0.049
meiotic cell cycle GO:0051321 171 0.049
negative regulation of response to stimulus GO:0048585 258 0.049
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.048
cell adhesion GO:0007155 136 0.047
organonitrogen compound metabolic process GO:1901564 318 0.047
regulation of localization GO:0032879 275 0.047
response to abiotic stimulus GO:0009628 341 0.046
negative regulation of rna metabolic process GO:0051253 251 0.046
cell proliferation GO:0008283 299 0.046
vesicle mediated transport GO:0016192 381 0.046
cell cycle checkpoint GO:0000075 95 0.045
cell migration GO:0016477 238 0.045
cellular amino acid metabolic process GO:0006520 61 0.043
mitotic cell cycle checkpoint GO:0007093 88 0.042
cellular protein localization GO:0034613 160 0.042
negative regulation of cellular biosynthetic process GO:0031327 277 0.041
lateral inhibition GO:0046331 206 0.041
larval development GO:0002164 104 0.041
negative regulation of cell cycle process GO:0010948 109 0.041
peptide metabolic process GO:0006518 80 0.041
oxoacid metabolic process GO:0043436 103 0.041
negative regulation of gene expression epigenetic GO:0045814 77 0.040
cell division GO:0051301 248 0.040
tube morphogenesis GO:0035239 191 0.040
apoptotic process GO:0006915 159 0.040
regulation of cellular response to stress GO:0080135 89 0.040
single organism biosynthetic process GO:0044711 206 0.040
positive regulation of endopeptidase activity GO:0010950 26 0.039
negative regulation of biosynthetic process GO:0009890 277 0.039
negative regulation of signaling GO:0023057 219 0.039
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 44 0.039
regulation of protein catabolic process GO:0042176 55 0.038
single organism catabolic process GO:0044712 228 0.038
single organism intracellular transport GO:1902582 207 0.038
regulation of programmed cell death GO:0043067 152 0.038
regulation of cellular protein catabolic process GO:1903362 44 0.038
negative regulation of signal transduction GO:0009968 206 0.038
development of primary sexual characteristics GO:0045137 50 0.037
cell motility GO:0048870 251 0.037
imaginal disc derived wing morphogenesis GO:0007476 337 0.037
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process GO:0031145 30 0.037
reproductive structure development GO:0048608 74 0.037
multicellular organismal aging GO:0010259 140 0.037
connective tissue development GO:0061448 3 0.037
establishment of localization in cell GO:0051649 402 0.037
regulation of cell cycle GO:0051726 291 0.036
organic substance catabolic process GO:1901575 308 0.036
regulation of catabolic process GO:0009894 170 0.036
chromatin modification GO:0016568 147 0.035
modification dependent protein catabolic process GO:0019941 78 0.035
nitrogen compound transport GO:0071705 85 0.035
positive regulation of proteolysis GO:0045862 52 0.035
regulation of cellular catabolic process GO:0031329 157 0.035
negative regulation of mitotic cell cycle GO:0045930 109 0.034
immune system process GO:0002376 347 0.034
organic substance transport GO:0071702 257 0.034
protein transport GO:0015031 155 0.034
dna metabolic process GO:0006259 227 0.033
Human
regulation of transport GO:0051049 181 0.032
positive regulation of biosynthetic process GO:0009891 316 0.032
negative regulation of nucleic acid templated transcription GO:1903507 240 0.032
cell cycle phase transition GO:0044770 140 0.032
carboxylic acid metabolic process GO:0019752 92 0.032
protein localization GO:0008104 284 0.032
protein dna complex subunit organization GO:0071824 86 0.032
Human
cellular ketone metabolic process GO:0042180 24 0.032
localization of cell GO:0051674 257 0.031
regulation of cell death GO:0010941 173 0.031
positive regulation of transport GO:0051050 92 0.031
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.030
intracellular signal transduction GO:0035556 300 0.030
positive regulation of response to stimulus GO:0048584 323 0.030
response to external biotic stimulus GO:0043207 293 0.029
anatomical structure homeostasis GO:0060249 97 0.029
determination of adult lifespan GO:0008340 137 0.029
dna repair GO:0006281 54 0.029
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.029
cullin deneddylation GO:0010388 3 0.028
sex differentiation GO:0007548 81 0.028
negative regulation of cell cycle GO:0045786 116 0.028
camera type eye development GO:0043010 4 0.028
single organism cellular localization GO:1902580 180 0.028
negative regulation of developmental process GO:0051093 201 0.028
mitotic dna integrity checkpoint GO:0044774 75 0.028
protein phosphorylation GO:0006468 169 0.027
negative regulation of cellular protein metabolic process GO:0032269 85 0.026
protein maturation GO:0051604 71 0.026
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 73 0.026
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.026
regulation of cell cycle process GO:0010564 181 0.026
central nervous system development GO:0007417 201 0.026
columnar cuboidal epithelial cell development GO:0002066 249 0.025
negative regulation of rna biosynthetic process GO:1902679 240 0.025
regulation of multi organism process GO:0043900 131 0.025
cellular macromolecule catabolic process GO:0044265 136 0.025
peptidyl lysine modification GO:0018205 57 0.025
positive regulation of cellular component organization GO:0051130 156 0.025
appendage development GO:0048736 401 0.025
mitotic g2 m transition checkpoint GO:0044818 70 0.025
positive regulation of phosphate metabolic process GO:0045937 139 0.025
gonad development GO:0008406 50 0.024
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.024
retina development in camera type eye GO:0060041 4 0.024
establishment of protein localization GO:0045184 163 0.024
cellular response to chemical stimulus GO:0070887 199 0.024
negative regulation of cellular component organization GO:0051129 108 0.023
regulation of cellular component biogenesis GO:0044087 201 0.023
regulation of apoptotic process GO:0042981 130 0.023
mitotic sister chromatid segregation GO:0000070 87 0.023
rna localization GO:0006403 115 0.023
actin filament based process GO:0030029 220 0.023
negative regulation of multicellular organismal process GO:0051241 142 0.023
positive regulation of cysteine type endopeptidase activity GO:2001056 24 0.022
regulation of phosphate metabolic process GO:0019220 210 0.022
regulation of phosphorus metabolic process GO:0051174 210 0.022
enzyme linked receptor protein signaling pathway GO:0007167 179 0.022
intracellular protein transport GO:0006886 104 0.022
response to other organism GO:0051707 293 0.022
mitotic g2 dna damage checkpoint GO:0007095 69 0.022
signal transduction by phosphorylation GO:0023014 107 0.022
signal transduction in response to dna damage GO:0042770 3 0.022
meiotic nuclear division GO:0007126 151 0.022
spermatid differentiation GO:0048515 114 0.022
regulation of cellular ketone metabolic process GO:0010565 3 0.022
protein processing GO:0016485 68 0.022
protein import into nucleus GO:0006606 51 0.021
positive regulation of cell motility GO:2000147 3 0.021
rna processing GO:0006396 147 0.021
negative regulation of molecular function GO:0044092 51 0.021
histone modification GO:0016570 106 0.021
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.020
meiotic cell cycle process GO:1903046 132 0.020
positive regulation of molecular function GO:0044093 136 0.020
morphogenesis of an epithelium GO:0002009 276 0.020
positive regulation of signaling GO:0023056 243 0.020
chromatin organization GO:0006325 207 0.020
Human
protein modification by small protein conjugation GO:0032446 79 0.020
protein complex assembly GO:0006461 200 0.020
Human
organonitrogen compound biosynthetic process GO:1901566 117 0.020
nucleocytoplasmic transport GO:0006913 72 0.020
mapk cascade GO:0000165 107 0.020
sister chromatid segregation GO:0000819 92 0.020
response to endogenous stimulus GO:0009719 119 0.020
regulation of chromosome organization GO:0033044 64 0.020
regulation of hydrolase activity GO:0051336 97 0.020
phagocytosis GO:0006909 215 0.019
regulation of peptidase activity GO:0052547 39 0.019
regulation of mitotic sister chromatid separation GO:0010965 28 0.019
heart development GO:0007507 82 0.019
amine metabolic process GO:0009308 12 0.019
regulation of mitotic sister chromatid segregation GO:0033047 28 0.019
regulation of cellular amine metabolic process GO:0033238 3 0.019
endocytosis GO:0006897 310 0.019
cellular homeostasis GO:0019725 80 0.019
chromatin remodeling GO:0006338 72 0.019
regulation of developmental growth GO:0048638 174 0.019
response to biotic stimulus GO:0009607 294 0.019
regulation of intracellular transport GO:0032386 64 0.019
positive regulation of cell death GO:0010942 69 0.018
tissue migration GO:0090130 155 0.018
dorsal ventral pattern formation GO:0009953 133 0.018
negative regulation of cell death GO:0060548 81 0.018
positive regulation of cell communication GO:0010647 250 0.018
protein modification by small protein conjugation or removal GO:0070647 106 0.018
tissue morphogenesis GO:0048729 297 0.018
mitotic dna damage checkpoint GO:0044773 74 0.018
g2 dna damage checkpoint GO:0031572 69 0.018
developmental growth GO:0048589 280 0.018
organic cyclic compound catabolic process GO:1901361 168 0.018
regulation of endopeptidase activity GO:0052548 36 0.018
cellular protein catabolic process GO:0044257 83 0.017
g1 s transition of mitotic cell cycle GO:0000082 31 0.017
centrosome organization GO:0051297 163 0.017
muscle structure development GO:0061061 224 0.017
positive regulation of signal transduction GO:0009967 223 0.017
regulation of immune system process GO:0002682 176 0.017
dna damage checkpoint GO:0000077 78 0.017
regulation of response to dna damage stimulus GO:2001020 23 0.017
maintenance of location GO:0051235 73 0.017
ovarian follicle cell development GO:0030707 248 0.017
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.017
cell cell signaling involved in cell fate commitment GO:0045168 210 0.017
stem cell differentiation GO:0048863 117 0.017
positive regulation of programmed cell death GO:0043068 62 0.017
response to organic substance GO:0010033 284 0.017
response to temperature stimulus GO:0009266 106 0.017
microtubule anchoring GO:0034453 11 0.017
regulation of dna templated transcription elongation GO:0032784 17 0.017
negative regulation of sister chromatid segregation GO:0033046 13 0.017
histone h3 k4 methylation GO:0051568 16 0.017
positive regulation of protein metabolic process GO:0051247 128 0.016
protein complex biogenesis GO:0070271 201 0.016
Human
positive regulation of peptidase activity GO:0010952 29 0.016
digestive tract morphogenesis GO:0048546 127 0.016
negative regulation of catabolic process GO:0009895 36 0.016
negative regulation of protein metabolic process GO:0051248 85 0.016
activation of cysteine type endopeptidase activity involved in apoptotic process GO:0006919 16 0.016
regulation of chromosome segregation GO:0051983 32 0.016
regulation of cell division GO:0051302 72 0.016
negative regulation of proteasomal protein catabolic process GO:1901799 16 0.016
positive regulation of catalytic activity GO:0043085 118 0.016
digestive system development GO:0055123 149 0.016
metaphase anaphase transition of cell cycle GO:0044784 28 0.016
regulation of anatomical structure morphogenesis GO:0022603 242 0.016
taxis GO:0042330 304 0.016
regulation of mapk cascade GO:0043408 92 0.016
regulation of catalytic activity GO:0050790 185 0.016
regulation of wnt signaling pathway GO:0030111 68 0.015
eggshell formation GO:0030703 105 0.015
head development GO:0060322 135 0.015
negative regulation of cellular catabolic process GO:0031330 34 0.015
regulation of mrna processing GO:0050684 71 0.015
biological adhesion GO:0022610 138 0.015
proteasomal protein catabolic process GO:0010498 59 0.015
gland morphogenesis GO:0022612 145 0.015
chemotaxis GO:0006935 249 0.015
epithelium migration GO:0090132 148 0.015
cellular macromolecule localization GO:0070727 220 0.015
spermatid development GO:0007286 98 0.015
dephosphorylation GO:0016311 51 0.015
segmentation GO:0035282 207 0.015
spindle checkpoint GO:0031577 11 0.014
nucleotide metabolic process GO:0009117 161 0.014
cardiovascular system development GO:0072358 82 0.014
response to heat GO:0009408 63 0.014
regulation of phosphorylation GO:0042325 147 0.014
neuron projection guidance GO:0097485 241 0.014
response to hexose GO:0009746 3 0.014
cell fate specification GO:0001708 71 0.014
nucleobase containing compound catabolic process GO:0034655 165 0.014
mrna processing GO:0006397 104 0.014
transcription elongation from rna polymerase ii promoter GO:0006368 18 0.014
regulation of metaphase anaphase transition of cell cycle GO:1902099 26 0.014
regulation of protein deacetylation GO:0090311 2 0.014
microtubule organizing center organization GO:0031023 168 0.014
regulation of mitotic metaphase anaphase transition GO:0030071 26 0.014
spindle assembly GO:0051225 80 0.014
regulation of gene expression epigenetic GO:0040029 128 0.014
actin cytoskeleton organization GO:0030036 206 0.014
protein targeting to nucleus GO:0044744 51 0.013
negative regulation of chromosome segregation GO:0051985 14 0.013
regulation of sister chromatid segregation GO:0033045 28 0.013
imaginal disc derived appendage development GO:0048737 399 0.013
protein import GO:0017038 55 0.013
salivary gland development GO:0007431 162 0.013
covalent chromatin modification GO:0016569 106 0.013
embryonic axis specification GO:0000578 107 0.013
telencephalon development GO:0021537 2 0.013
nuclear import GO:0051170 51 0.013
protein localization to nucleus GO:0034504 55 0.013
negative regulation of proteolysis involved in cellular protein catabolic process GO:1903051 17 0.013
peptidyl amino acid modification GO:0018193 105 0.013
regulation of cellular localization GO:0060341 136 0.013
photoreceptor cell development GO:0042461 96 0.013
nuclear transport GO:0051169 72 0.013
hematopoietic progenitor cell differentiation GO:0002244 1 0.013
negative regulation of mitotic sister chromatid separation GO:2000816 13 0.013
gland development GO:0048732 191 0.013
defense response to other organism GO:0098542 225 0.012
positive regulation of phosphorus metabolic process GO:0010562 139 0.012
neurological system process GO:0050877 358 0.012
regulation of mrna splicing via spliceosome GO:0048024 64 0.012
protein ubiquitination GO:0016567 70 0.012
rna splicing via transesterification reactions GO:0000375 73 0.012
regulation of heterochromatin assembly GO:0031445 8 0.012
positive regulation of phosphorylation GO:0042327 87 0.012
positive regulation of cell migration GO:0030335 2 0.012
multicellular organismal homeostasis GO:0048871 41 0.012
regulation of response to external stimulus GO:0032101 115 0.012
response to glucose GO:0009749 2 0.012
embryonic pattern specification GO:0009880 174 0.012
mesenchymal cell differentiation GO:0048762 1 0.012
tissue homeostasis GO:0001894 36 0.012
regulation of organelle organization GO:0033043 196 0.012
regulation of cytoplasmic transport GO:1903649 47 0.012
positive regulation of intracellular transport GO:0032388 42 0.012
response to oxygen containing compound GO:1901700 200 0.012
posttranscriptional regulation of gene expression GO:0010608 145 0.012
regulation of cellular amino acid metabolic process GO:0006521 0 0.012
appendage morphogenesis GO:0035107 397 0.012
regulation of multicellular organismal development GO:2000026 414 0.012
regulation of nucleocytoplasmic transport GO:0046822 35 0.012
male meiosis GO:0007140 52 0.012
compound eye morphogenesis GO:0001745 249 0.012
negative regulation of chromosome organization GO:2001251 19 0.011
molting cycle GO:0042303 56 0.011
chromatin silencing GO:0006342 76 0.011
nucleoside phosphate metabolic process GO:0006753 162 0.011
mrna splicing via spliceosome GO:0000398 73 0.011
nucleobase containing compound transport GO:0015931 56 0.011
protein dephosphorylation GO:0006470 27 0.011
response to radiation GO:0009314 155 0.011
multicellular organismal reproductive behavior GO:0033057 110 0.011
small molecule biosynthetic process GO:0044283 37 0.011
epithelial cell migration GO:0010631 148 0.011
regulation of rna splicing GO:0043484 69 0.011
regulation of nuclear division GO:0051783 58 0.011
multi organism reproductive behavior GO:0044705 121 0.011
negative regulation of developmental growth GO:0048640 64 0.011
regulation of gene silencing GO:0060968 63 0.011
response to bacterium GO:0009617 198 0.011
single organism nuclear import GO:1902593 51 0.011
mrna metabolic process GO:0016071 124 0.011
carbohydrate derivative metabolic process GO:1901135 217 0.011
positive regulation of nucleocytoplasmic transport GO:0046824 24 0.011
genitalia development GO:0048806 26 0.011
response to monosaccharide GO:0034284 4 0.011
positive regulation of multi organism process GO:0043902 40 0.011
positive regulation of cellular protein metabolic process GO:0032270 118 0.011
regulation of cysteine type endopeptidase activity GO:2000116 27 0.010
cellular response to hexose stimulus GO:0071331 1 0.010
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 4 0.010
chromatin assembly GO:0031497 48 0.010
Human
er associated ubiquitin dependent protein catabolic process GO:0030433 3 0.010
epithelial tube morphogenesis GO:0060562 88 0.010
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.010
cellular amine metabolic process GO:0044106 12 0.010
regulation of intracellular signal transduction GO:1902531 236 0.010
cellular response to carbohydrate stimulus GO:0071322 4 0.010
protein localization to organelle GO:0033365 82 0.010
mitotic spindle organization GO:0007052 220 0.010

CG8223 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.040
disease of cellular proliferation DOID:14566 0 0.018
organ system cancer DOID:0050686 0 0.016
cancer DOID:162 0 0.016
nervous system disease DOID:863 0 0.016
musculoskeletal system disease DOID:17 0 0.012