Drosophila melanogaster

30 known processes

Vps45 (Dmel_CG8228)

Vacuolar protein sorting 45

(Aliases: VPS45,MENE(3R)-C,MENE (3R)-C,Dmel\CG8228,CG8228,Vps45p,dVps45)

Vps45 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
single organism membrane fusion GO:0044801 42 0.248
positive regulation of gtpase activity GO:0043547 43 0.226
purine nucleoside metabolic process GO:0042278 127 0.199
intracellular signal transduction GO:0035556 300 0.183
ribonucleoside triphosphate metabolic process GO:0009199 119 0.170
gtp catabolic process GO:0006184 72 0.147
regulation of phosphorus metabolic process GO:0051174 210 0.144
ras protein signal transduction GO:0007265 88 0.142
regulation of phosphate metabolic process GO:0019220 210 0.131
positive regulation of nucleoside metabolic process GO:0045979 47 0.127
purine nucleoside triphosphate catabolic process GO:0009146 108 0.123
intracellular transport GO:0046907 228 0.121
purine ribonucleoside catabolic process GO:0046130 112 0.118
actin cytoskeleton organization GO:0030036 206 0.115
purine containing compound metabolic process GO:0072521 155 0.112
ribonucleoside triphosphate catabolic process GO:0009203 108 0.110
nucleotide metabolic process GO:0009117 161 0.109
ribose phosphate metabolic process GO:0019693 145 0.107
regulation of tube architecture open tracheal system GO:0035152 68 0.106
carbohydrate derivative catabolic process GO:1901136 118 0.104
single organism intracellular transport GO:1902582 207 0.103
purine nucleotide metabolic process GO:0006163 146 0.101
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.101
positive regulation of nucleotide catabolic process GO:0030813 46 0.096
regulation of ras protein signal transduction GO:0046578 93 0.091
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.090
vesicle mediated transport GO:0016192 381 0.090
purine nucleoside catabolic process GO:0006152 112 0.089
purine ribonucleotide metabolic process GO:0009150 145 0.089
nucleoside metabolic process GO:0009116 127 0.089
endosomal vesicle fusion GO:0034058 4 0.088
glycosyl compound metabolic process GO:1901657 127 0.088
protein localization GO:0008104 284 0.085
establishment of localization in cell GO:0051649 402 0.085
purine containing compound catabolic process GO:0072523 112 0.083
regulation of cellular catabolic process GO:0031329 157 0.082
purine nucleoside triphosphate metabolic process GO:0009144 119 0.080
ion transport GO:0006811 145 0.079
regulation of gtp catabolic process GO:0033124 44 0.079
regulation of nucleoside metabolic process GO:0009118 50 0.078
ribonucleoside metabolic process GO:0009119 127 0.076
purine nucleotide catabolic process GO:0006195 109 0.075
nucleobase containing small molecule metabolic process GO:0055086 174 0.074
endosomal transport GO:0016197 44 0.074
positive regulation of gtp catabolic process GO:0033126 43 0.074
ribonucleotide metabolic process GO:0009259 145 0.073
nucleoside catabolic process GO:0009164 112 0.071
cellular protein localization GO:0034613 160 0.071
guanosine containing compound catabolic process GO:1901069 74 0.071
imaginal disc derived wing morphogenesis GO:0007476 337 0.071
purine ribonucleotide catabolic process GO:0009154 109 0.069
purine ribonucleoside metabolic process GO:0046128 127 0.067
ribonucleotide catabolic process GO:0009261 109 0.067
actin filament based process GO:0030029 220 0.067
single organism catabolic process GO:0044712 228 0.066
transmembrane transport GO:0055085 139 0.065
nucleoside phosphate metabolic process GO:0006753 162 0.065
positive regulation of nucleotide metabolic process GO:0045981 55 0.064
endomembrane system organization GO:0010256 119 0.063
regulation of nucleotide catabolic process GO:0030811 48 0.062
locomotory behavior GO:0007626 176 0.061
positive regulation of purine nucleotide metabolic process GO:1900544 55 0.061
nucleoside phosphate catabolic process GO:1901292 110 0.060
membrane organization GO:0061024 112 0.060
small gtpase mediated signal transduction GO:0007264 88 0.059
ribonucleoside catabolic process GO:0042454 112 0.059
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.059
positive regulation of ras gtpase activity GO:0032320 36 0.057
nucleoside triphosphate catabolic process GO:0009143 108 0.057
guanosine containing compound metabolic process GO:1901068 74 0.057
regulation of intracellular signal transduction GO:1902531 236 0.056
imaginal disc derived appendage morphogenesis GO:0035114 395 0.056
organonitrogen compound metabolic process GO:1901564 318 0.055
carbohydrate derivative metabolic process GO:1901135 217 0.054
response to organonitrogen compound GO:0010243 75 0.053
mitotic spindle organization GO:0007052 220 0.053
positive regulation of phosphorus metabolic process GO:0010562 139 0.053
organic substance catabolic process GO:1901575 308 0.053
positive regulation of purine nucleotide catabolic process GO:0033123 46 0.053
appendage morphogenesis GO:0035107 397 0.053
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.052
regulation of cellular amine metabolic process GO:0033238 3 0.051
single organism behavior GO:0044708 391 0.050
germarium derived egg chamber formation GO:0007293 101 0.050
positive regulation of phosphate metabolic process GO:0045937 139 0.050
gtp metabolic process GO:0046039 72 0.049
nucleotide catabolic process GO:0009166 109 0.048
nucleoside triphosphate metabolic process GO:0009141 120 0.048
regulation of localization GO:0032879 275 0.048
tissue morphogenesis GO:0048729 297 0.048
cellular catabolic process GO:0044248 372 0.047
regulation of catalytic activity GO:0050790 185 0.046
regulation of catabolic process GO:0009894 170 0.046
organophosphate metabolic process GO:0019637 195 0.046
macromolecule catabolic process GO:0009057 161 0.045
glycosyl compound catabolic process GO:1901658 112 0.045
regulation of molecular function GO:0065009 217 0.045
epithelial cell differentiation GO:0030855 322 0.044
actin filament organization GO:0007015 126 0.043
negative regulation of cell communication GO:0010648 223 0.042
single organism cellular localization GO:1902580 180 0.042
morphogenesis of an epithelium GO:0002009 276 0.042
cellular nitrogen compound catabolic process GO:0044270 165 0.042
intracellular protein transport GO:0006886 104 0.040
negative regulation of signal transduction GO:0009968 206 0.040
organophosphate catabolic process GO:0046434 112 0.040
compound eye morphogenesis GO:0001745 249 0.040
skin development GO:0043588 65 0.039
regulation of gtpase activity GO:0043087 44 0.039
regulation of purine nucleotide metabolic process GO:1900542 62 0.038
positive regulation of catabolic process GO:0009896 105 0.038
catabolic process GO:0009056 409 0.038
regulation of cell morphogenesis GO:0022604 163 0.037
activation of ras gtpase activity GO:0032856 6 0.037
proteolysis GO:0006508 192 0.037
protein modification process GO:0036211 438 0.037
heterocycle catabolic process GO:0046700 166 0.036
organonitrogen compound catabolic process GO:1901565 128 0.035
appendage development GO:0048736 401 0.035
g protein coupled receptor signaling pathway GO:0007186 136 0.035
cellular protein modification process GO:0006464 438 0.033
post embryonic appendage morphogenesis GO:0035120 385 0.033
regionalization GO:0003002 416 0.032
wing disc morphogenesis GO:0007472 344 0.032
forebrain development GO:0030900 2 0.032
regulation of small gtpase mediated signal transduction GO:0051056 93 0.032
negative regulation of signaling GO:0023057 219 0.031
cellular macromolecular complex assembly GO:0034622 153 0.031
dendrite morphogenesis GO:0048813 199 0.031
positive regulation of cellular catabolic process GO:0031331 95 0.031
organelle fusion GO:0048284 46 0.031
regulation of purine nucleotide catabolic process GO:0033121 48 0.030
regulation of mapk cascade GO:0043408 92 0.030
endocytosis GO:0006897 310 0.030
morphogenesis of a polarized epithelium GO:0001738 93 0.029
axonogenesis GO:0007409 290 0.029
imaginal disc derived appendage development GO:0048737 399 0.029
cellular amine metabolic process GO:0044106 12 0.029
negative regulation of cellular metabolic process GO:0031324 382 0.028
regulation of neuron differentiation GO:0045664 103 0.028
regulation of cellular protein metabolic process GO:0032268 243 0.028
spindle organization GO:0007051 253 0.028
oocyte microtubule cytoskeleton polarization GO:0008103 22 0.028
tissue migration GO:0090130 155 0.027
cellular response to dna damage stimulus GO:0006974 223 0.027
organic cyclic compound catabolic process GO:1901361 168 0.027
epidermis development GO:0008544 65 0.027
oocyte differentiation GO:0009994 145 0.027
nucleobase containing compound catabolic process GO:0034655 165 0.026
axis specification GO:0009798 167 0.026
regulation of erk1 and erk2 cascade GO:0070372 39 0.026
neuron recognition GO:0008038 101 0.025
eye photoreceptor cell development GO:0042462 81 0.025
amine metabolic process GO:0009308 12 0.025
signal transduction by phosphorylation GO:0023014 107 0.025
regulation of anatomical structure morphogenesis GO:0022603 242 0.025
regulation of protein metabolic process GO:0051246 256 0.025
small molecule metabolic process GO:0044281 305 0.025
regulation of transport GO:0051049 181 0.025
chromosome organization GO:0051276 360 0.024
axon development GO:0061564 297 0.024
regulation of phosphorylation GO:0042325 147 0.024
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.024
tube development GO:0035295 244 0.024
single organism membrane organization GO:0044802 93 0.024
cellular macromolecule localization GO:0070727 220 0.024
regulation of ras gtpase activity GO:0032318 38 0.023
negative regulation of response to stimulus GO:0048585 258 0.022
regulation of cellular amino acid metabolic process GO:0006521 0 0.022
female meiotic division GO:0007143 70 0.022
oocyte axis specification GO:0007309 108 0.022
aromatic compound catabolic process GO:0019439 166 0.022
epithelial cell development GO:0002064 274 0.022
positive regulation of molecular function GO:0044093 136 0.022
epidermal cell differentiation GO:0009913 51 0.022
regulation of protein localization GO:0032880 76 0.022
positive regulation of response to stimulus GO:0048584 323 0.022
mapk cascade GO:0000165 107 0.022
photoreceptor cell differentiation GO:0046530 170 0.021
phagocytosis GO:0006909 215 0.021
immune system process GO:0002376 347 0.021
negative regulation of phosphorus metabolic process GO:0010563 45 0.021
regulation of cell cycle phase transition GO:1901987 130 0.020
establishment of protein localization GO:0045184 163 0.020
regulation of cellular component size GO:0032535 98 0.020
protein localization to plasma membrane GO:0072659 13 0.020
camera type eye development GO:0043010 4 0.020
anterior posterior axis specification embryo GO:0008595 103 0.020
negative regulation of cell cycle phase transition GO:1901988 103 0.020
establishment of planar polarity GO:0001736 87 0.020
regulation of cell projection organization GO:0031344 92 0.019
anterior posterior pattern specification GO:0009952 136 0.019
germ line cyst formation GO:0048134 44 0.019
establishment or maintenance of bipolar cell polarity GO:0061245 34 0.019
protein catabolic process GO:0030163 101 0.019
epithelial tube morphogenesis GO:0060562 88 0.019
positive regulation of cell communication GO:0010647 250 0.019
tube morphogenesis GO:0035239 191 0.019
compound eye photoreceptor development GO:0042051 78 0.018
regulation of cellular ketone metabolic process GO:0010565 3 0.018
branching involved in open tracheal system development GO:0060446 45 0.018
positive regulation of hydrolase activity GO:0051345 78 0.018
brain development GO:0007420 120 0.018
peptidyl threonine phosphorylation GO:0018107 2 0.018
cell maturation GO:0048469 144 0.017
regulation of hydrolase activity GO:0051336 97 0.017
negative regulation of mapk cascade GO:0043409 23 0.017
compound eye photoreceptor cell differentiation GO:0001751 140 0.017
positive regulation of cell development GO:0010720 61 0.017
erbb signaling pathway GO:0038127 58 0.017
regulation of response to stress GO:0080134 200 0.017
regulation of cell shape GO:0008360 113 0.017
ovarian follicle cell migration GO:0007297 121 0.017
protein dna complex assembly GO:0065004 63 0.017
camera type eye morphogenesis GO:0048593 2 0.017
chemotaxis GO:0006935 249 0.017
organic substance transport GO:0071702 257 0.016
segmentation GO:0035282 207 0.016
axon guidance GO:0007411 233 0.016
branching morphogenesis of an epithelial tube GO:0048754 45 0.016
female germ line cyst formation GO:0048135 42 0.016
embryonic axis specification GO:0000578 107 0.016
head development GO:0060322 135 0.016
regulation of anatomical structure size GO:0090066 163 0.016
organelle assembly GO:0070925 198 0.016
compound eye development GO:0048749 307 0.016
neuron projection guidance GO:0097485 241 0.016
hair cell differentiation GO:0035315 47 0.016
protein transport GO:0015031 155 0.016
response to external biotic stimulus GO:0043207 293 0.015
lysosomal transport GO:0007041 13 0.015
organelle fission GO:0048285 340 0.015
chromatin organization GO:0006325 207 0.015
regulation of intracellular transport GO:0032386 64 0.015
establishment of organelle localization GO:0051656 122 0.015
imaginal disc derived wing hair organization GO:0035317 45 0.015
lipid localization GO:0010876 54 0.015
positive regulation of phosphorylation GO:0042327 87 0.015
negative regulation of mitotic cell cycle GO:0045930 109 0.015
nuclear division GO:0000280 332 0.015
positive regulation of gene expression GO:0010628 290 0.015
positive regulation of signaling GO:0023056 243 0.014
regulation of nucleotide metabolic process GO:0006140 62 0.014
single organism biosynthetic process GO:0044711 206 0.014
negative regulation of intracellular signal transduction GO:1902532 57 0.014
cell cycle checkpoint GO:0000075 95 0.014
response to organophosphorus GO:0046683 2 0.014
erk1 and erk2 cascade GO:0070371 39 0.014
adult locomotory behavior GO:0008344 76 0.014
endosome to lysosome transport GO:0008333 7 0.014
negative regulation of protein metabolic process GO:0051248 85 0.014
adult behavior GO:0030534 137 0.014
cell recognition GO:0008037 102 0.014
positive regulation of signal transduction GO:0009967 223 0.014
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.014
negative regulation of cell cycle process GO:0010948 109 0.013
chemosensory behavior GO:0007635 106 0.013
protein complex assembly GO:0006461 200 0.013
protein phosphorylation GO:0006468 169 0.013
developmental maturation GO:0021700 172 0.013
phosphorylation GO:0016310 294 0.013
neurological system process GO:0050877 358 0.013
central nervous system development GO:0007417 201 0.013
mitotic nuclear division GO:0007067 213 0.013
cell junction organization GO:0034330 57 0.013
protein complex biogenesis GO:0070271 201 0.013
homeostatic process GO:0042592 199 0.013
positive regulation of cellular amine metabolic process GO:0033240 0 0.013
protein processing GO:0016485 68 0.013
developmental growth involved in morphogenesis GO:0060560 65 0.013
nephron development GO:0072006 3 0.012
regulation of protein modification process GO:0031399 112 0.012
regulation of cellular localization GO:0060341 136 0.012
cellular protein catabolic process GO:0044257 83 0.012
anion transport GO:0006820 41 0.012
histone modification GO:0016570 106 0.012
positive regulation of intracellular signal transduction GO:1902533 116 0.012
regulation of cell size GO:0008361 63 0.012
response to biotic stimulus GO:0009607 294 0.012
histolysis GO:0007559 102 0.012
negative regulation of biosynthetic process GO:0009890 277 0.012
peripheral nervous system development GO:0007422 52 0.012
neuron maturation GO:0042551 31 0.012
positive regulation of multicellular organismal process GO:0051240 143 0.011
regulation of protein depolymerization GO:1901879 27 0.011
rho protein signal transduction GO:0007266 14 0.011
open tracheal system development GO:0007424 204 0.011
regulation of proteolysis GO:0030162 87 0.011
positive regulation of developmental process GO:0051094 143 0.011
negative regulation of phosphorylation GO:0042326 35 0.011
ion homeostasis GO:0050801 55 0.011
monovalent inorganic cation transport GO:0015672 40 0.011
male meiosis GO:0007140 52 0.011
synaptic transmission GO:0007268 288 0.011
developmental programmed cell death GO:0010623 138 0.010
regulation of rab protein signal transduction GO:0032483 7 0.010
positive regulation of ras protein signal transduction GO:0046579 43 0.010
telencephalon development GO:0021537 2 0.010
establishment or maintenance of apical basal cell polarity GO:0035088 34 0.010
regulation of cell differentiation GO:0045595 302 0.010
establishment of protein localization to organelle GO:0072594 62 0.010
regulation of cytoskeleton organization GO:0051493 89 0.010
chaeta morphogenesis GO:0008407 42 0.010
negative regulation of erk1 and erk2 cascade GO:0070373 3 0.010

Vps45 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.018