Drosophila melanogaster

38 known processes

Tcp-1zeta (Dmel_CG8231)

T-cp1zeta

(Aliases: l(1)G0022,Dmel\CG8231,L(1)g0022,Rcd3,l(1)G0027,l(1)G0057,CG8231,CCT6,Tcp-1-zeta,TCP-1-zeta,TCP-1zeta)

Tcp-1zeta biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
mitotic spindle organization GO:0007052 220 0.948
single fertilization GO:0007338 24 0.934
spindle assembly involved in mitosis GO:0090307 50 0.731
spindle organization GO:0007051 253 0.649
protein transport GO:0015031 155 0.526
cell death GO:0008219 279 0.489
programmed cell death GO:0012501 257 0.468
fertilization GO:0009566 26 0.465
death GO:0016265 284 0.436
spindle assembly GO:0051225 80 0.424
microtubule cytoskeleton organization involved in mitosis GO:1902850 52 0.412
positive regulation of cellular biosynthetic process GO:0031328 316 0.367
organelle fission GO:0048285 340 0.349
embryo development ending in birth or egg hatching GO:0009792 152 0.349
nuclear division GO:0000280 332 0.333
microtubule organizing center organization GO:0031023 168 0.326
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.323
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.306
cytoplasmic microtubule organization GO:0031122 22 0.270
mitotic nuclear division GO:0007067 213 0.270
negative regulation of gene expression GO:0010629 387 0.240
small molecule metabolic process GO:0044281 305 0.230
larval development GO:0002164 104 0.223
positive regulation of transcription dna templated GO:0045893 266 0.222
vesicle mediated transport GO:0016192 381 0.211
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.210
positive regulation of rna metabolic process GO:0051254 271 0.197
organonitrogen compound metabolic process GO:1901564 318 0.174
centrosome duplication GO:0051298 121 0.173
response to biotic stimulus GO:0009607 294 0.161
cell recognition GO:0008037 102 0.159
protein complex biogenesis GO:0070271 201 0.151
sensory organ morphogenesis GO:0090596 260 0.147
positive regulation of nucleic acid templated transcription GO:1903508 266 0.138
positive regulation of biosynthetic process GO:0009891 316 0.136
positive regulation of rna biosynthetic process GO:1902680 266 0.124
organelle assembly GO:0070925 198 0.120
intracellular transport GO:0046907 228 0.118
positive regulation of gene expression GO:0010628 290 0.117
apoptotic process GO:0006915 159 0.116
transcription from rna polymerase ii promoter GO:0006366 368 0.115
response to temperature stimulus GO:0009266 106 0.111
cell proliferation GO:0008283 299 0.100
purine nucleotide catabolic process GO:0006195 109 0.097
immune response GO:0006955 246 0.095
negative regulation of transcription dna templated GO:0045892 237 0.094
endocytosis GO:0006897 310 0.092
intracellular protein transport GO:0006886 104 0.088
cellular macromolecule localization GO:0070727 220 0.086
regulation of protein metabolic process GO:0051246 256 0.085
intracellular signal transduction GO:0035556 300 0.085
protein complex assembly GO:0006461 200 0.074
response to abiotic stimulus GO:0009628 341 0.073
purine containing compound metabolic process GO:0072521 155 0.072
response to other organism GO:0051707 293 0.071
cellular amino acid metabolic process GO:0006520 61 0.071
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.068
organophosphate catabolic process GO:0046434 112 0.066
posttranscriptional regulation of gene expression GO:0010608 145 0.064
regulation of cell death GO:0010941 173 0.058
regulation of intracellular signal transduction GO:1902531 236 0.057
development of primary sexual characteristics GO:0045137 50 0.056
positive regulation of cell death GO:0010942 69 0.055
negative regulation of biosynthetic process GO:0009890 277 0.054
positive regulation of molecular function GO:0044093 136 0.053
establishment of protein localization GO:0045184 163 0.052
single organism biosynthetic process GO:0044711 206 0.052
proteolysis GO:0006508 192 0.052
regulation of innate immune response GO:0045088 71 0.051
macromolecular complex assembly GO:0065003 256 0.048
positive regulation of response to stimulus GO:0048584 323 0.047
regulation of cell cycle GO:0051726 291 0.047
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.046
negative regulation of rna metabolic process GO:0051253 251 0.045
response to oxidative stress GO:0006979 86 0.044
sex differentiation GO:0007548 81 0.042
reproductive structure development GO:0048608 74 0.042
negative regulation of cellular metabolic process GO:0031324 382 0.042
cellular catabolic process GO:0044248 372 0.042
mitotic spindle elongation GO:0000022 81 0.041
positive regulation of cell communication GO:0010647 250 0.041
regulation of cell proliferation GO:0042127 163 0.039
protein targeting GO:0006605 64 0.038
positive regulation of macromolecule metabolic process GO:0010604 405 0.037
regulation of molecular function GO:0065009 217 0.037
organic substance transport GO:0071702 257 0.037
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.035
positive regulation of signal transduction GO:0009967 223 0.035
regulation of cellular ketone metabolic process GO:0010565 3 0.034
single organism catabolic process GO:0044712 228 0.033
growth GO:0040007 359 0.033
positive regulation of signaling GO:0023056 243 0.032
positive regulation of intracellular signal transduction GO:1902533 116 0.032
cellular response to chemical stimulus GO:0070887 199 0.031
tissue morphogenesis GO:0048729 297 0.031
reproductive system development GO:0061458 74 0.030
developmental programmed cell death GO:0010623 138 0.029
positive regulation of catalytic activity GO:0043085 118 0.028
head development GO:0060322 135 0.028
purine nucleoside triphosphate metabolic process GO:0009144 119 0.028
positive regulation of programmed cell death GO:0043068 62 0.028
negative regulation of response to stimulus GO:0048585 258 0.027
eye morphogenesis GO:0048592 260 0.027
receptor mediated endocytosis GO:0006898 21 0.026
negative regulation of cell death GO:0060548 81 0.026
camera type eye development GO:0043010 4 0.026
cellular response to dna damage stimulus GO:0006974 223 0.025
cytoplasmic transport GO:0016482 130 0.025
regulation of mrna processing GO:0050684 71 0.025
regulation of immune response GO:0050776 118 0.025
negative regulation of developmental process GO:0051093 201 0.025
ribonucleoside metabolic process GO:0009119 127 0.025
genitalia development GO:0048806 26 0.025
nuclear transport GO:0051169 72 0.024
brain development GO:0007420 120 0.024
biological adhesion GO:0022610 138 0.024
innate immune response GO:0045087 144 0.024
regulation of mrna splicing via spliceosome GO:0048024 64 0.024
body morphogenesis GO:0010171 2 0.024
negative regulation of cell communication GO:0010648 223 0.024
regulation of programmed cell death GO:0043067 152 0.023
regulation of catabolic process GO:0009894 170 0.023
positive regulation of cellular component organization GO:0051130 156 0.023
meiotic cell cycle GO:0051321 171 0.023
regulation of apoptotic process GO:0042981 130 0.023
response to external biotic stimulus GO:0043207 293 0.022
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.022
embryonic organ development GO:0048568 50 0.022
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.022
morphogenesis of an epithelium GO:0002009 276 0.022
negative regulation of rna biosynthetic process GO:1902679 240 0.021
anterior posterior pattern specification GO:0009952 136 0.021
gonad development GO:0008406 50 0.021
regulation of transport GO:0051049 181 0.021
positive regulation of phosphorus metabolic process GO:0010562 139 0.020
regulation of defense response GO:0031347 102 0.020
negative regulation of signaling GO:0023057 219 0.020
embryonic axis specification GO:0000578 107 0.020
nucleocytoplasmic transport GO:0006913 72 0.020
purine ribonucleoside monophosphate metabolic process GO:0009167 50 0.020
taxis GO:0042330 304 0.020
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.019
nucleobase containing small molecule metabolic process GO:0055086 174 0.019
single organism cell adhesion GO:0098602 47 0.019
centrosome organization GO:0051297 163 0.019
ribonucleoside catabolic process GO:0042454 112 0.018
negative regulation of cellular protein metabolic process GO:0032269 85 0.018
regulation of phosphate metabolic process GO:0019220 210 0.018
phagocytosis GO:0006909 215 0.018
cell adhesion GO:0007155 136 0.018
g1 s transition of mitotic cell cycle GO:0000082 31 0.018
regulation of cell cycle process GO:0010564 181 0.018
mrna processing GO:0006397 104 0.017
regulation of intracellular transport GO:0032386 64 0.017
defense response to gram negative bacterium GO:0050829 94 0.017
purine nucleoside metabolic process GO:0042278 127 0.017
single organism intracellular transport GO:1902582 207 0.017
response to endogenous stimulus GO:0009719 119 0.017
carbohydrate derivative metabolic process GO:1901135 217 0.016
glycosyl compound metabolic process GO:1901657 127 0.016
protein modification process GO:0036211 438 0.016
eye development GO:0001654 323 0.016
regulation of cellular protein metabolic process GO:0032268 243 0.016
protein localization GO:0008104 284 0.016
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.016
regulation of proteolysis GO:0030162 87 0.016
gland development GO:0048732 191 0.015
organic substance catabolic process GO:1901575 308 0.015
aromatic compound catabolic process GO:0019439 166 0.015
multicellular organismal reproductive behavior GO:0033057 110 0.015
positive regulation of apoptotic process GO:0043065 47 0.015
establishment of localization in cell GO:0051649 402 0.015
nucleoside metabolic process GO:0009116 127 0.015
response to organic substance GO:0010033 284 0.015
regulation of catalytic activity GO:0050790 185 0.015
cellular protein localization GO:0034613 160 0.014
regulation of cellular amine metabolic process GO:0033238 3 0.014
peptidyl amino acid modification GO:0018193 105 0.014
chromatin remodeling GO:0006338 72 0.014
nucleobase containing compound catabolic process GO:0034655 165 0.014
carboxylic acid metabolic process GO:0019752 92 0.014
ribose phosphate metabolic process GO:0019693 145 0.014
organic acid biosynthetic process GO:0016053 15 0.014
negative regulation of cell proliferation GO:0008285 69 0.013
regulation of organelle organization GO:0033043 196 0.013
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.013
mitotic cell cycle phase transition GO:0044772 138 0.013
negative regulation of cellular biosynthetic process GO:0031327 277 0.013
centrosome cycle GO:0007098 137 0.013
embryonic pattern specification GO:0009880 174 0.012
regulation of mitotic cell cycle GO:0007346 190 0.012
segmentation GO:0035282 207 0.012
ribonucleotide metabolic process GO:0009259 145 0.012
negative regulation of programmed cell death GO:0043069 72 0.012
regulation of purine nucleotide metabolic process GO:1900542 62 0.012
ubiquitin dependent protein catabolic process GO:0006511 78 0.012
regulation of localization GO:0032879 275 0.012
developmental maturation GO:0021700 172 0.012
nucleoside triphosphate metabolic process GO:0009141 120 0.012
purine nucleotide metabolic process GO:0006163 146 0.012
response to oxygen containing compound GO:1901700 200 0.012
organic acid metabolic process GO:0006082 103 0.012
positive regulation of cell motility GO:2000147 3 0.012
cellular ketone metabolic process GO:0042180 24 0.012
response to nutrient levels GO:0031667 114 0.012
protein destabilization GO:0031648 2 0.012
regulation of phosphorylation GO:0042325 147 0.011
endomembrane system organization GO:0010256 119 0.011
positive regulation of defense response GO:0031349 59 0.011
mapk cascade GO:0000165 107 0.011
purine ribonucleotide metabolic process GO:0009150 145 0.011
response to hypoxia GO:0001666 53 0.011
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 73 0.011
nucleotide catabolic process GO:0009166 109 0.011
purine nucleoside monophosphate metabolic process GO:0009126 50 0.011
multi multicellular organism process GO:0044706 123 0.011
cell cycle phase transition GO:0044770 140 0.011
purine nucleoside catabolic process GO:0006152 112 0.011
developmental growth GO:0048589 280 0.011
dendrite morphogenesis GO:0048813 199 0.011
regulation of nucleoside metabolic process GO:0009118 50 0.011
negative regulation of protein binding GO:0032091 1 0.011
purine ribonucleoside catabolic process GO:0046130 112 0.011
nucleoside triphosphate catabolic process GO:0009143 108 0.010
organonitrogen compound catabolic process GO:1901565 128 0.010
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 1 0.010
activation of innate immune response GO:0002218 4 0.010
positive regulation of protein metabolic process GO:0051247 128 0.010
regulation of cell substrate adhesion GO:0010810 2 0.010
cardiovascular system development GO:0072358 82 0.010
nucleoside phosphate metabolic process GO:0006753 162 0.010
organic cyclic compound catabolic process GO:1901361 168 0.010
dendrite development GO:0016358 204 0.010
positive regulation of immune response GO:0050778 63 0.010
regulation of viral genome replication GO:0045069 4 0.010

Tcp-1zeta disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.030
disease of cellular proliferation DOID:14566 0 0.018
organ system cancer DOID:0050686 0 0.018
cancer DOID:162 0 0.018