Drosophila melanogaster

53 known processes

eIF4E-5 (Dmel_CG8277)

CG8277 gene product from transcript CG8277-RA

(Aliases: CG8277,eIF4E,Dmel\CG8277,CT24507)

eIF4E-5 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
long term memory GO:0007616 62 0.162
single organism behavior GO:0044708 391 0.156
developmental programmed cell death GO:0010623 138 0.075
exocrine system development GO:0035272 162 0.064
tissue death GO:0016271 102 0.058
body morphogenesis GO:0010171 2 0.057
protein localization GO:0008104 284 0.056
organic substance transport GO:0071702 257 0.052
intracellular signal transduction GO:0035556 300 0.050
cellular macromolecule localization GO:0070727 220 0.050
autophagic cell death GO:0048102 83 0.046
regulation of translation GO:0006417 56 0.045
Human Fly
respiratory system development GO:0060541 213 0.045
Rat
translation GO:0006412 69 0.044
establishment of localization in cell GO:0051649 402 0.043
spermatogenesis GO:0007283 200 0.043
Fly
positive regulation of cellular biosynthetic process GO:0031328 316 0.041
Fly
lateral inhibition GO:0046331 206 0.041
positive regulation of protein metabolic process GO:0051247 128 0.041
Fly
catabolic process GO:0009056 409 0.041
neurological system process GO:0050877 358 0.040
negative regulation of rna biosynthetic process GO:1902679 240 0.039
positive regulation of macromolecule metabolic process GO:0010604 405 0.035
Fly
negative regulation of biosynthetic process GO:0009890 277 0.034
memory GO:0007613 94 0.033
tube development GO:0035295 244 0.033
Rat
gene silencing GO:0016458 138 0.031
negative regulation of nucleic acid templated transcription GO:1903507 240 0.030
cell death GO:0008219 279 0.029
cellular catabolic process GO:0044248 372 0.029
regulation of protein metabolic process GO:0051246 256 0.028
Human Fly
negative regulation of gene expression GO:0010629 387 0.028
positive regulation of cell communication GO:0010647 250 0.028
regionalization GO:0003002 416 0.028
appendage morphogenesis GO:0035107 397 0.028
positive regulation of gene expression GO:0010628 290 0.027
Fly
cellular protein localization GO:0034613 160 0.027
regulation of intracellular signal transduction GO:1902531 236 0.026
jak stat cascade GO:0007259 49 0.026
head development GO:0060322 135 0.026
cellular response to chemical stimulus GO:0070887 199 0.025
positive regulation of response to stimulus GO:0048584 323 0.025
positive regulation of signaling GO:0023056 243 0.025
organic substance catabolic process GO:1901575 308 0.025
defense response GO:0006952 300 0.024
proteolysis GO:0006508 192 0.024
regulation of cellular catabolic process GO:0031329 157 0.024
negative regulation of cellular biosynthetic process GO:0031327 277 0.024
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.024
Fly
regulation of phosphorus metabolic process GO:0051174 210 0.024
protein modification process GO:0036211 438 0.023
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.023
single organism catabolic process GO:0044712 228 0.023
death GO:0016265 284 0.023
positive regulation of biosynthetic process GO:0009891 316 0.023
Fly
intracellular transport GO:0046907 228 0.022
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.022
regulation of cellular protein metabolic process GO:0032268 243 0.022
Human Fly
cognition GO:0050890 141 0.022
response to external biotic stimulus GO:0043207 293 0.022
organonitrogen compound metabolic process GO:1901564 318 0.022
positive regulation of signal transduction GO:0009967 223 0.021
post embryonic appendage morphogenesis GO:0035120 385 0.021
wing disc morphogenesis GO:0007472 344 0.021
spermatid development GO:0007286 98 0.021
positive regulation of cellular protein metabolic process GO:0032270 118 0.021
Fly
telencephalon development GO:0021537 2 0.020
regulation of catalytic activity GO:0050790 185 0.020
negative regulation of rna metabolic process GO:0051253 251 0.020
cell proliferation GO:0008283 299 0.020
cuticle development GO:0042335 86 0.020
positive regulation of intracellular signal transduction GO:1902533 116 0.019
imaginal disc derived appendage development GO:0048737 399 0.019
salivary gland cell autophagic cell death GO:0035071 83 0.019
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.019
negative regulation of transcription dna templated GO:0045892 237 0.019
forebrain development GO:0030900 2 0.019
vesicle mediated transport GO:0016192 381 0.018
histolysis GO:0007559 102 0.018
programmed cell death GO:0012501 257 0.018
regulation of localization GO:0032879 275 0.018
brain development GO:0007420 120 0.018
imaginal disc derived wing morphogenesis GO:0007476 337 0.018
phosphorylation GO:0016310 294 0.017
negative regulation of gene expression epigenetic GO:0045814 77 0.017
mushroom body development GO:0016319 70 0.017
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.017
small molecule metabolic process GO:0044281 305 0.017
response to abiotic stimulus GO:0009628 341 0.017
cell motility GO:0048870 251 0.017
gland morphogenesis GO:0022612 145 0.016
imaginal disc derived appendage morphogenesis GO:0035114 395 0.016
regulation of gene expression epigenetic GO:0040029 128 0.016
negative regulation of cellular metabolic process GO:0031324 382 0.016
spindle organization GO:0007051 253 0.016
taxis GO:0042330 304 0.016
chitin based cuticle development GO:0040003 49 0.016
positive regulation of molecular function GO:0044093 136 0.015
rna localization GO:0006403 115 0.015
cilium morphogenesis GO:0060271 39 0.015
protein catabolic process GO:0030163 101 0.015
ribonucleotide metabolic process GO:0009259 145 0.015
carbohydrate derivative metabolic process GO:1901135 217 0.015
regulation of gene silencing GO:0060968 63 0.015
salivary gland development GO:0007431 162 0.015
regulation of cellular amine metabolic process GO:0033238 3 0.015
regulation of cell proliferation GO:0042127 163 0.015
mitotic spindle organization GO:0007052 220 0.015
regulation of phosphate metabolic process GO:0019220 210 0.015
chemotaxis GO:0006935 249 0.015
regulation of molecular function GO:0065009 217 0.015
appendage development GO:0048736 401 0.015
response to temperature stimulus GO:0009266 106 0.014
dorsal closure GO:0007391 79 0.014
positive regulation of phosphate metabolic process GO:0045937 139 0.014
gland development GO:0048732 191 0.014
cell cell signaling involved in cell fate commitment GO:0045168 210 0.014
cell growth GO:0016049 108 0.014
protein localization to organelle GO:0033365 82 0.014
regulation of cellular amino acid metabolic process GO:0006521 0 0.014
rrna processing GO:0006364 3 0.014
regulation of cell cycle GO:0051726 291 0.014
Human
positive regulation of phosphorus metabolic process GO:0010562 139 0.014
regulation of catabolic process GO:0009894 170 0.014
cell cycle checkpoint GO:0000075 95 0.014
response to monosaccharide GO:0034284 4 0.014
endocytosis GO:0006897 310 0.014
nucleus organization GO:0006997 45 0.014
monocarboxylic acid transport GO:0015718 3 0.014
kidney development GO:0001822 3 0.014
cellular amino acid metabolic process GO:0006520 61 0.014
protein transport GO:0015031 155 0.014
cytoplasmic transport GO:0016482 130 0.013
nucleobase containing small molecule metabolic process GO:0055086 174 0.013
salivary gland morphogenesis GO:0007435 145 0.013
cellular response to organic substance GO:0071310 132 0.013
nucleotide metabolic process GO:0009117 161 0.013
regulation of anatomical structure size GO:0090066 163 0.013
purine ribonucleotide metabolic process GO:0009150 145 0.013
secretion by cell GO:0032940 101 0.013
chromatin silencing GO:0006342 76 0.013
translational initiation GO:0006413 11 0.013
phagocytosis GO:0006909 215 0.013
positive regulation of hydrolase activity GO:0051345 78 0.013
response to hexose GO:0009746 3 0.013
cellular ketone metabolic process GO:0042180 24 0.013
intracellular protein transport GO:0006886 104 0.012
response to organic substance GO:0010033 284 0.012
regulation of cellular ketone metabolic process GO:0010565 3 0.012
organophosphate metabolic process GO:0019637 195 0.012
cellular protein modification process GO:0006464 438 0.012
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.012
posttranscriptional regulation of gene expression GO:0010608 145 0.012
Human Fly
regulation of cellular localization GO:0060341 136 0.012
sperm individualization GO:0007291 48 0.012
stem cell proliferation GO:0072089 88 0.012
response to glucose GO:0009749 2 0.012
response to biotic stimulus GO:0009607 294 0.012
regulation of cellular component size GO:0032535 98 0.012
transcription from rna polymerase ii promoter GO:0006366 368 0.011
response to starvation GO:0042594 97 0.011
macromolecule catabolic process GO:0009057 161 0.011
ribonucleoside triphosphate metabolic process GO:0009199 119 0.011
neuroblast proliferation GO:0007405 74 0.011
cell projection assembly GO:0030031 94 0.011
cell maturation GO:0048469 144 0.011
positive regulation of phosphorylation GO:0042327 87 0.011
ras protein signal transduction GO:0007265 88 0.011
establishment of protein localization GO:0045184 163 0.011
positive regulation of catabolic process GO:0009896 105 0.011
dna integrity checkpoint GO:0031570 81 0.011
cell division GO:0051301 248 0.011
single organism cellular localization GO:1902580 180 0.011
actin cytoskeleton organization GO:0030036 206 0.011
toxin metabolic process GO:0009404 2 0.011
regulation of phosphorylation GO:0042325 147 0.011
response to lipopolysaccharide GO:0032496 4 0.011
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.011
response to oxygen containing compound GO:1901700 200 0.011
small gtpase mediated signal transduction GO:0007264 88 0.010
protein targeting GO:0006605 64 0.010
sensory perception of chemical stimulus GO:0007606 116 0.010
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.010
cell migration GO:0016477 238 0.010
morphogenesis of an epithelium GO:0002009 276 0.010
response to other organism GO:0051707 293 0.010
rna processing GO:0006396 147 0.010
single organism intracellular transport GO:1902582 207 0.010
ubiquitin dependent protein catabolic process GO:0006511 78 0.010

eIF4E-5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.012
nervous system disease DOID:863 0 0.012
disease of metabolism DOID:0014667 0 0.010