Drosophila melanogaster

10 known processes

Ef1alpha48D (Dmel_CG8280)

Elongation factor 1alpha48D

(Aliases: Ef1alpha48E,eEF1alpha,Efalpha48D,l(2)k07303,EF-1[a],EF-1alphaF1,EF-1alphaF[[1]],EF-1,ef-1alpha,Dm0084,EF1-alpha,EF-1a,F1 EF-1alpha,EF1alpha48D,clone 2.46,EF1alpha,anon-EST:Liang-1.17,l(2)01275,EF,1275,Ef1a10,EF1alpha 48D,EF-1alpha,F1,clone 1.17,DmEF1,Ef1a48D,EF-1alpha F1,l(2)1275,Dmel\CG8280,anon-EST:Liang-2.46,EF-1alphaF,CG8280,Ef1alpha1)

Ef1alpha48D biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
mitotic spindle elongation GO:0000022 81 0.696
positive regulation of cellular biosynthetic process GO:0031328 316 0.249
mitotic spindle organization GO:0007052 220 0.229
rrna processing GO:0006364 3 0.226
ribose phosphate biosynthetic process GO:0046390 28 0.209
intracellular signal transduction GO:0035556 300 0.204
cell death GO:0008219 279 0.204
purine containing compound biosynthetic process GO:0072522 30 0.150
organelle assembly GO:0070925 198 0.149
spindle elongation GO:0051231 83 0.138
positive regulation of macromolecule metabolic process GO:0010604 405 0.127
positive regulation of gene expression GO:0010628 290 0.115
embryo development ending in birth or egg hatching GO:0009792 152 0.107
translational elongation GO:0006414 4 0.103
Yeast
ncrna metabolic process GO:0034660 43 0.102
microtubule organizing center organization GO:0031023 168 0.100
single organism intracellular transport GO:1902582 207 0.095
Yeast
positive regulation of biosynthetic process GO:0009891 316 0.094
ribonucleoprotein complex subunit organization GO:0071826 28 0.089
response to other organism GO:0051707 293 0.084
response to pain GO:0048265 3 0.082
positive regulation of protein metabolic process GO:0051247 128 0.081
ribose phosphate metabolic process GO:0019693 145 0.077
translation GO:0006412 69 0.075
Yeast
appendage development GO:0048736 401 0.069
immune system process GO:0002376 347 0.064
associative learning GO:0008306 65 0.064
response to organic substance GO:0010033 284 0.062
positive regulation of phosphate metabolic process GO:0045937 139 0.061
intracellular transport GO:0046907 228 0.060
Yeast
negative regulation of signaling GO:0023057 219 0.058
single organism behavior GO:0044708 391 0.058
ribonucleoprotein complex biogenesis GO:0022613 31 0.058
asymmetric protein localization GO:0008105 33 0.058
g protein coupled receptor signaling pathway GO:0007186 136 0.056
apoptotic process GO:0006915 159 0.054
cellular response to chemical stimulus GO:0070887 199 0.054
centrosome organization GO:0051297 163 0.053
compound eye development GO:0048749 307 0.052
circadian sleep wake cycle process GO:0022410 24 0.051
positive regulation of response to stimulus GO:0048584 323 0.051
spindle organization GO:0007051 253 0.050
positive regulation of cellular protein metabolic process GO:0032270 118 0.049
body morphogenesis GO:0010171 2 0.048
organ growth GO:0035265 56 0.047
metal ion homeostasis GO:0055065 44 0.046
circadian sleep wake cycle sleep GO:0050802 23 0.046
positive regulation of signal transduction GO:0009967 223 0.045
spindle assembly GO:0051225 80 0.045
cyclic nucleotide metabolic process GO:0009187 28 0.044
programmed cell death GO:0012501 257 0.044
heart development GO:0007507 82 0.043
regulation of developmental growth GO:0048638 174 0.042
cytosolic calcium ion homeostasis GO:0051480 11 0.040
vesicle mediated transport GO:0016192 381 0.040
protein k48 linked ubiquitination GO:0070936 3 0.040
positive regulation of hydrolase activity GO:0051345 78 0.040
ribonucleotide metabolic process GO:0009259 145 0.040
nucleoside phosphate biosynthetic process GO:1901293 34 0.040
learning GO:0007612 75 0.038
dna repair GO:0006281 54 0.038
nucleotide biosynthetic process GO:0009165 34 0.036
positive regulation of developmental process GO:0051094 143 0.035
sensory perception of pain GO:0019233 4 0.035
regulation of small gtpase mediated signal transduction GO:0051056 93 0.035
gonad development GO:0008406 50 0.035
sleep GO:0030431 49 0.034
detection of mechanical stimulus involved in sensory perception of pain GO:0050966 2 0.033
response to oxygen containing compound GO:1901700 200 0.033
response to hormone GO:0009725 45 0.033
positive regulation of signaling GO:0023056 243 0.033
secretion by cell GO:0032940 101 0.033
positive regulation of catalytic activity GO:0043085 118 0.033
positive regulation of multicellular organismal process GO:0051240 143 0.032
response to nitrogen compound GO:1901698 90 0.032
secretion GO:0046903 109 0.032
cellular ion homeostasis GO:0006873 39 0.032
detection of stimulus involved in sensory perception GO:0050906 92 0.032
regulation of synaptic transmission GO:0050804 69 0.031
purine ribonucleotide biosynthetic process GO:0009152 28 0.031
negative regulation of multicellular organismal process GO:0051241 142 0.031
sensory perception of mechanical stimulus GO:0050954 72 0.030
adult behavior GO:0030534 137 0.030
phosphorylation GO:0016310 294 0.030
neuron neuron synaptic transmission GO:0007270 14 0.030
carbohydrate homeostasis GO:0033500 12 0.030
locomotory behavior GO:0007626 176 0.029
negative regulation of cell communication GO:0010648 223 0.029
carbohydrate metabolic process GO:0005975 82 0.028
forebrain development GO:0030900 2 0.028
purine nucleotide biosynthetic process GO:0006164 29 0.028
positive regulation of phosphorus metabolic process GO:0010562 139 0.028
positive regulation of nervous system development GO:0051962 69 0.028
cellular metal ion homeostasis GO:0006875 31 0.028
cognition GO:0050890 141 0.028
snrna 3 end processing GO:0034472 14 0.028
detection of abiotic stimulus GO:0009582 66 0.027
reproductive system development GO:0061458 74 0.027
purine ribonucleotide metabolic process GO:0009150 145 0.027
regulation of neurogenesis GO:0050767 158 0.027
regulation of tube size GO:0035150 46 0.027
adenylate cyclase activating g protein coupled receptor signaling pathway GO:0007189 9 0.026
memory GO:0007613 94 0.026
positive regulation of phosphorylation GO:0042327 87 0.026
macromolecule catabolic process GO:0009057 161 0.026
action potential GO:0001508 13 0.026
rho protein signal transduction GO:0007266 14 0.026
regulation of glycogen metabolic process GO:0070873 3 0.026
cellular macromolecule catabolic process GO:0044265 136 0.026
regulation of nervous system development GO:0051960 248 0.025
multicellular organismal response to stress GO:0033555 5 0.025
cellular response to oxygen containing compound GO:1901701 79 0.025
homeostatic process GO:0042592 199 0.025
eye pigment granule organization GO:0008057 12 0.024
defense response to other organism GO:0098542 225 0.024
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.024
regulation of cell cycle GO:0051726 291 0.024
positive regulation of developmental growth GO:0048639 62 0.024
response to lipid GO:0033993 38 0.024
protein modification process GO:0036211 438 0.023
cellular catabolic process GO:0044248 372 0.023
regulation of cell development GO:0060284 215 0.023
ras protein signal transduction GO:0007265 88 0.023
camp biosynthetic process GO:0006171 17 0.023
mitotic dna damage checkpoint GO:0044773 74 0.023
regulation of cell cycle phase transition GO:1901987 130 0.023
development of primary sexual characteristics GO:0045137 50 0.023
centrosome duplication GO:0051298 121 0.022
ribonucleoprotein complex assembly GO:0022618 23 0.022
positive regulation of neurogenesis GO:0050769 41 0.022
negative regulation of signal transduction GO:0009968 206 0.022
ribonucleotide biosynthetic process GO:0009260 28 0.022
cellular carbohydrate catabolic process GO:0044275 2 0.022
cellular response to dna damage stimulus GO:0006974 223 0.022
regulation of cell differentiation GO:0045595 302 0.022
regulation of circadian rhythm GO:0042752 49 0.021
cation transport GO:0006812 110 0.021
regulation of synaptic plasticity GO:0048167 14 0.021
regulation of cell projection organization GO:0031344 92 0.021
regulation of membrane potential GO:0042391 35 0.021
carbohydrate derivative metabolic process GO:1901135 217 0.021
positive regulation of translation GO:0045727 12 0.020
activation of innate immune response GO:0002218 4 0.020
imaginal disc pattern formation GO:0007447 91 0.020
synaptic transmission GO:0007268 288 0.019
response to alkaloid GO:0043279 26 0.019
tripartite regional subdivision GO:0007351 103 0.019
positive regulation of camp metabolic process GO:0030816 8 0.019
regulation of protein metabolic process GO:0051246 256 0.019
positive regulation of cell development GO:0010720 61 0.019
positive regulation of molecular function GO:0044093 136 0.019
response to alcohol GO:0097305 95 0.019
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.019
cellular polysaccharide metabolic process GO:0044264 11 0.019
regulation of circadian sleep wake cycle GO:0042749 25 0.019
organonitrogen compound metabolic process GO:1901564 318 0.019
regulation of mitotic cell cycle phase transition GO:1901990 130 0.019
guanosine containing compound metabolic process GO:1901068 74 0.018
cyclic nucleotide biosynthetic process GO:0009190 25 0.018
positive regulation of nucleic acid templated transcription GO:1903508 266 0.018
sex differentiation GO:0007548 81 0.018
organophosphate biosynthetic process GO:0090407 46 0.018
death GO:0016265 284 0.018
protein localization GO:0008104 284 0.018
medium chain fatty acid metabolic process GO:0051791 1 0.018
circadian sleep wake cycle GO:0042745 28 0.018
glycosyl compound metabolic process GO:1901657 127 0.018
modification dependent protein catabolic process GO:0019941 78 0.018
camp metabolic process GO:0046058 19 0.018
positive regulation of nucleotide metabolic process GO:0045981 55 0.018
ribosomal large subunit biogenesis GO:0042273 1 0.018
mitotic dna integrity checkpoint GO:0044774 75 0.018
positive regulation of immune response GO:0050778 63 0.017
cellular divalent inorganic cation homeostasis GO:0072503 23 0.017
adenylate cyclase modulating g protein coupled receptor signaling pathway GO:0007188 17 0.017
response to bacterium GO:0009617 198 0.017
purine nucleoside biosynthetic process GO:0042451 3 0.017
negative regulation of intracellular signal transduction GO:1902532 57 0.016
rna processing GO:0006396 147 0.016
mitotic cytokinesis GO:0000281 50 0.016
post embryonic appendage morphogenesis GO:0035120 385 0.016
mitotic g2 dna damage checkpoint GO:0007095 69 0.016
sensory organ morphogenesis GO:0090596 260 0.016
negative regulation of mitotic cell cycle GO:0045930 109 0.016
regulation of behavior GO:0050795 75 0.016
cell cycle checkpoint GO:0000075 95 0.016
gene silencing GO:0016458 138 0.016
cellular pigmentation GO:0033059 12 0.016
innate immune response activating signal transduction GO:0002758 2 0.015
regulation of intracellular signal transduction GO:1902531 236 0.015
positive regulation of erk1 and erk2 cascade GO:0070374 36 0.015
embryonic development via the syncytial blastoderm GO:0001700 148 0.015
regulation of blood circulation GO:1903522 21 0.015
catabolic process GO:0009056 409 0.015
cyclic purine nucleotide metabolic process GO:0052652 25 0.015
purine nucleotide metabolic process GO:0006163 146 0.015
positive regulation of purine nucleotide metabolic process GO:1900544 55 0.015
cellular response to organic substance GO:0071310 132 0.015
organelle localization GO:0051640 148 0.015
heart process GO:0003015 37 0.015
establishment of organelle localization GO:0051656 122 0.015
nephron epithelium development GO:0072009 3 0.015
cation homeostasis GO:0055080 51 0.015
cellular response to lipopolysaccharide GO:0071222 3 0.015
cell cell signaling involved in cell fate commitment GO:0045168 210 0.015
pattern recognition receptor signaling pathway GO:0002221 2 0.015
regulation of phosphorylation GO:0042325 147 0.015
establishment or maintenance of polarity of follicular epithelium GO:0016334 26 0.014
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.014
head development GO:0060322 135 0.014
gtp catabolic process GO:0006184 72 0.014
multi multicellular organism process GO:0044706 123 0.014
cellular response to organic cyclic compound GO:0071407 32 0.014
organic substance transport GO:0071702 257 0.014
Yeast
nucleoside triphosphate metabolic process GO:0009141 120 0.014
macromolecular complex assembly GO:0065003 256 0.014
regulation of programmed cell death GO:0043067 152 0.014
dna damage checkpoint GO:0000077 78 0.014
zymogen activation GO:0031638 20 0.014
wing disc morphogenesis GO:0007472 344 0.014
nuclear transport GO:0051169 72 0.014
Yeast
learning or memory GO:0007611 141 0.014
response to ketone GO:1901654 34 0.014
hematopoietic progenitor cell differentiation GO:0002244 1 0.014
chemical homeostasis GO:0048878 92 0.014
tube morphogenesis GO:0035239 191 0.014
cytoskeleton dependent cytokinesis GO:0061640 81 0.014
response to endogenous stimulus GO:0009719 119 0.014
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 17 0.013
positive regulation of cyclic nucleotide metabolic process GO:0030801 9 0.013
histolysis GO:0007559 102 0.013
phospholipid homeostasis GO:0055091 1 0.013
negative regulation of cell cycle phase transition GO:1901988 103 0.013
regulation of cellular protein metabolic process GO:0032268 243 0.013
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.013
circadian behavior GO:0048512 76 0.013
protein modification by small protein conjugation GO:0032446 79 0.013
response to organonitrogen compound GO:0010243 75 0.013
cellular response to endogenous stimulus GO:0071495 80 0.013
regulation of cellular component biogenesis GO:0044087 201 0.013
protein heterooligomerization GO:0051291 4 0.013
response to temperature stimulus GO:0009266 106 0.013
negative regulation of response to stimulus GO:0048585 258 0.013
nuclear division GO:0000280 332 0.013
generation of precursor metabolites and energy GO:0006091 42 0.013
centrosome cycle GO:0007098 137 0.013
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.013
activation of cysteine type endopeptidase activity involved in apoptotic process GO:0006919 16 0.013
mitotic cell cycle phase transition GO:0044772 138 0.013
regulation of ras protein signal transduction GO:0046578 93 0.013
regulation of phosphorus metabolic process GO:0051174 210 0.013
purine containing compound metabolic process GO:0072521 155 0.013
positive regulation of i kappab kinase nf kappab signaling GO:0043123 1 0.012
spindle assembly involved in mitosis GO:0090307 50 0.012
response to lipopolysaccharide GO:0032496 4 0.012
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 10 0.012
response to peptide hormone GO:0043434 29 0.012
rna interference GO:0016246 27 0.012
photoreceptor cell differentiation GO:0046530 170 0.012
regulation of camp metabolic process GO:0030814 12 0.012
protein maturation GO:0051604 71 0.012
guanosine containing compound catabolic process GO:1901069 74 0.012
developmental growth GO:0048589 280 0.012
nucleocytoplasmic transport GO:0006913 72 0.012
Yeast
positive regulation of cytosolic calcium ion concentration GO:0007204 10 0.012
regulation of cyclic nucleotide metabolic process GO:0030799 13 0.012
cellular response to molecule of bacterial origin GO:0071219 3 0.012
regulation of neuron differentiation GO:0045664 103 0.012
axis specification GO:0009798 167 0.012
visual learning GO:0008542 4 0.012
gtp metabolic process GO:0046039 72 0.012
organonitrogen compound biosynthetic process GO:1901566 117 0.012
positive regulation of catabolic process GO:0009896 105 0.012
positive regulation of apoptotic process GO:0043065 47 0.012
circulatory system development GO:0072359 82 0.012
cytokinesis GO:0000910 90 0.012
detection of stimulus GO:0051606 156 0.012
regulation of molecular function GO:0065009 217 0.012
negative regulation of catabolic process GO:0009895 36 0.012
mitotic cell cycle checkpoint GO:0007093 88 0.012
ncrna processing GO:0034470 30 0.012
regulation of catalytic activity GO:0050790 185 0.012
salivary gland cell autophagic cell death GO:0035071 83 0.012
regulation of phosphate metabolic process GO:0019220 210 0.011
cellular response to monosaccharide stimulus GO:0071326 2 0.011
nucleobase containing small molecule metabolic process GO:0055086 174 0.011
organic substance catabolic process GO:1901575 308 0.011
autophagic cell death GO:0048102 83 0.011
immune system development GO:0002520 57 0.011
snrna processing GO:0016180 14 0.011
protein transmembrane transport GO:0071806 4 0.011
regulation of multicellular organism growth GO:0040014 40 0.011
imaginal disc derived appendage development GO:0048737 399 0.011
negative regulation of gene expression GO:0010629 387 0.011
calcium ion homeostasis GO:0055074 23 0.011
energy derivation by oxidation of organic compounds GO:0015980 32 0.011
cellular response to biotic stimulus GO:0071216 4 0.011
protein processing GO:0016485 68 0.011
immune response activating signal transduction GO:0002757 2 0.011
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 3 0.011
positive regulation of intracellular signal transduction GO:1902533 116 0.011
regulation of gene expression epigenetic GO:0040029 128 0.011
regulation of multi organism process GO:0043900 131 0.011
ubiquitin dependent protein catabolic process GO:0006511 78 0.011
regionalization GO:0003002 416 0.011
lateral inhibition GO:0046331 206 0.011
antibacterial humoral response GO:0019731 44 0.011
immune response regulating signaling pathway GO:0002764 2 0.011
protein ubiquitination GO:0016567 70 0.011
positive regulation of cell projection organization GO:0031346 29 0.011
limb development GO:0060173 1 0.011
regulation of catabolic process GO:0009894 170 0.010
negative regulation of developmental process GO:0051093 201 0.010
polysaccharide metabolic process GO:0005976 11 0.010
golgi vesicle transport GO:0048193 27 0.010
endocytosis GO:0006897 310 0.010
g2 dna damage checkpoint GO:0031572 69 0.010
rna 3 end processing GO:0031123 45 0.010
cell cycle arrest GO:0007050 4 0.010
single organism carbohydrate metabolic process GO:0044723 72 0.010
nitrogen compound transport GO:0071705 85 0.010
Yeast
mitotic nuclear division GO:0007067 213 0.010
nucleobase containing compound transport GO:0015931 56 0.010
Yeast
small molecule metabolic process GO:0044281 305 0.010
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.010
appendage morphogenesis GO:0035107 397 0.010
ribonucleoside triphosphate metabolic process GO:0009199 119 0.010
cranial nerve development GO:0021545 1 0.010
cell growth GO:0016049 108 0.010
regulation of steroid metabolic process GO:0019218 2 0.010
negative regulation of synapse assembly GO:0051964 39 0.010
monocarboxylic acid transport GO:0015718 3 0.010
regulation of circadian sleep wake cycle sleep GO:0045187 21 0.010
protein acetylation GO:0006473 39 0.010

Ef1alpha48D disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.319
familial hypertriglyceridemia DOID:0050527 0 0.319
lipid metabolism disorder DOID:3146 0 0.319
inherited metabolic disorder DOID:655 0 0.319
hair disease DOID:421 0 0.054
disease of anatomical entity DOID:7 0 0.054
integumentary system disease DOID:16 0 0.054
hypotrichosis DOID:4535 0 0.020
nervous system disease DOID:863 0 0.019
cardiovascular system disease DOID:1287 0 0.015
central nervous system disease DOID:331 0 0.013
immune system disease DOID:2914 0 0.012
anemia DOID:2355 0 0.012
hematopoietic system disease DOID:74 0 0.012
neurodegenerative disease DOID:1289 0 0.011