Drosophila melanogaster

0 known processes

HLHm3 (Dmel_CG8346)

E(spl) region transcript m3

(Aliases: CG8346,E(spl)M3,E(spl)-m3,Dmel\CG8346,E(spl)C,E(spl)C m3,E(spl)m3/m4,E(Spl)-HLH-m3,HLH-m3,bHLHc14,E(spl)m3,m3,HLHM3)

HLHm3 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
neuron fate determination GO:0048664 1 0.954
Mouse
r7 cell differentiation GO:0045466 43 0.954
Fly
neuronal stem cell maintenance GO:0097150 4 0.787
Human Mouse Rat
sex determination GO:0007530 18 0.734
Fly
nephron epithelium morphogenesis GO:0072088 3 0.722
Mouse
nephron epithelium development GO:0072009 3 0.705
Mouse
regulation of cell differentiation GO:0045595 302 0.650
Human Zebrafish Mouse Rat Fly
nephron morphogenesis GO:0072028 3 0.631
Mouse
dosage compensation GO:0007549 16 0.613
Fly
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.604
Zebrafish Mouse Rat Fly
sensory organ precursor cell fate determination GO:0016360 19 0.604
Fly
embryonic morphogenesis GO:0048598 206 0.588
Zebrafish Mouse
kidney epithelium development GO:0072073 3 0.569
Mouse
open tracheal system development GO:0007424 204 0.568
Fly
nephron development GO:0072006 3 0.557
Mouse
larval behavior GO:0030537 42 0.553
Fly
regulation of glial cell differentiation GO:0045685 1 0.534
Mouse
glial cell fate commitment GO:0021781 3 0.528
Mouse
nephron tubule development GO:0072080 3 0.528
Mouse
axon ensheathment in central nervous system GO:0032291 3 0.502
Mouse
sensory organ morphogenesis GO:0090596 260 0.492
Fly
positive regulation of bmp signaling pathway GO:0030513 5 0.484
Mouse
adult locomotory behavior GO:0008344 76 0.477
Fly
tyrosine phosphorylation of stat protein GO:0007260 1 0.467
Mouse
negative regulation of nucleic acid templated transcription GO:1903507 240 0.458
Zebrafish Mouse Rat Fly
sensory organ boundary specification GO:0008052 22 0.457
Fly
tube morphogenesis GO:0035239 191 0.456
Mouse Fly
regulation of cell development GO:0060284 215 0.451
Zebrafish Mouse Rat Fly
kidney morphogenesis GO:0060993 3 0.439
Mouse
cell fate determination involved in pattern specification GO:0060582 19 0.436
Fly
stem cell proliferation GO:0072089 88 0.430
Fly
anterior posterior pattern specification GO:0009952 136 0.419
Zebrafish Mouse Worm
stem cell maintenance GO:0019827 67 0.418
Human Mouse Rat
respiratory system development GO:0060541 213 0.412
Fly
regulation of neuroblast proliferation GO:1902692 34 0.411
Fly
embryonic epithelial tube formation GO:0001838 6 0.408
Mouse
regulation of gene expression epigenetic GO:0040029 128 0.396
Fly
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 4 0.394
Mouse
connective tissue development GO:0061448 3 0.394
Human Mouse
nephron tubule morphogenesis GO:0072078 3 0.390
Mouse
kidney development GO:0001822 3 0.390
Mouse
nerve development GO:0021675 6 0.368
Mouse
telencephalon development GO:0021537 2 0.363
Mouse
eye morphogenesis GO:0048592 260 0.350
Fly
formation of organ boundary GO:0010160 30 0.345
Fly
nuclear division GO:0000280 332 0.336
Fly
compound eye development GO:0048749 307 0.331
Fly
tube formation GO:0035148 21 0.331
Mouse
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.325
Zebrafish Mouse Rat Fly
gliogenesis GO:0042063 80 0.325
Zebrafish Mouse Rat
r1 r6 cell differentiation GO:0048052 4 0.322
Fly
camera type eye development GO:0043010 4 0.318
Mouse
regulation of intracellular signal transduction GO:1902531 236 0.316
Mouse
notch signaling pathway GO:0007219 120 0.313
Human Zebrafish Mouse Fly
regulation of nervous system development GO:0051960 248 0.309
Zebrafish Mouse Rat Fly
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.307
Mouse
positive regulation of transcription dna templated GO:0045893 266 0.300
Mouse
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.300
Zebrafish Mouse Rat Fly
negative regulation of developmental process GO:0051093 201 0.296
Human Zebrafish Mouse Rat
positive regulation of cellular amine metabolic process GO:0033240 0 0.296
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.292
Zebrafish Mouse Rat Fly
negative regulation of stem cell differentiation GO:2000737 8 0.291
Human
small molecule metabolic process GO:0044281 305 0.290
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.284
Mouse
regulation of timing of cell differentiation GO:0048505 1 0.282
Mouse
compound eye morphogenesis GO:0001745 249 0.282
Fly
positive regulation of macromolecule metabolic process GO:0010604 405 0.277
Zebrafish Mouse
positive regulation of rna metabolic process GO:0051254 271 0.277
Mouse
sex determination establishment of x a ratio GO:0007540 1 0.275
Fly
neuron fate commitment GO:0048663 50 0.274
Mouse
regulation of neurogenesis GO:0050767 158 0.269
Zebrafish Mouse Rat Fly
transcription from rna polymerase ii promoter GO:0006366 368 0.269
Mouse Rat Fly
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.269
Mouse Rat Fly
bmp signaling pathway GO:0030509 27 0.268
Mouse
negative regulation of rna metabolic process GO:0051253 251 0.266
Zebrafish Mouse Rat Fly
tube development GO:0035295 244 0.264
Zebrafish Mouse Fly
imaginal disc pattern formation GO:0007447 91 0.263
Fly
regulation of organelle organization GO:0033043 196 0.260
Fly
hindbrain development GO:0030902 2 0.260
Mouse
primary sex determination soma GO:0007539 2 0.259
Fly
eye development GO:0001654 323 0.258
Zebrafish Mouse Fly
single organism behavior GO:0044708 391 0.253
Fly
rhythmic process GO:0048511 106 0.248
Mouse
peripheral nervous system development GO:0007422 52 0.248
Zebrafish
regulation of response to dna damage stimulus GO:2001020 23 0.245
Fly
nephron tubule formation GO:0072079 3 0.241
Mouse
negative regulation of cellular metabolic process GO:0031324 382 0.240
Zebrafish Mouse Rat Fly
morphogenesis of an epithelium GO:0002009 276 0.240
Mouse
adult behavior GO:0030534 137 0.238
Fly
regulation of multicellular organismal development GO:2000026 414 0.235
Zebrafish Mouse Rat Fly
negative regulation of rna biosynthetic process GO:1902679 240 0.234
Zebrafish Mouse Rat Fly
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090100 9 0.229
Mouse
regulation of mitosis GO:0007088 56 0.222
Fly
neuroblast proliferation GO:0007405 74 0.220
Fly
positive regulation of molecular function GO:0044093 136 0.215
Zebrafish
negative regulation of cell development GO:0010721 62 0.215
Zebrafish Mouse Rat
regulation of tyrosine phosphorylation of stat protein GO:0042509 1 0.214
Mouse
hair cell differentiation GO:0035315 47 0.214
Mouse
somatic sex determination GO:0018993 2 0.213
Fly
jak stat cascade GO:0007259 49 0.212
Mouse
lateral inhibition GO:0046331 206 0.211
positive regulation of rna biosynthetic process GO:1902680 266 0.211
Mouse
locomotory behavior GO:0007626 176 0.210
Fly
photoreceptor cell differentiation GO:0046530 170 0.209
Fly
forebrain development GO:0030900 2 0.209
Mouse Rat
positive regulation of signaling GO:0023056 243 0.208
Mouse
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 3 0.207
Zebrafish
cell fate specification GO:0001708 71 0.204
Worm
tissue morphogenesis GO:0048729 297 0.202
Mouse
dendrite development GO:0016358 204 0.201
Fly
epidermis development GO:0008544 65 0.200
Mouse Worm
formation of anatomical boundary GO:0048859 37 0.200
Fly
regulation of cellular amino acid metabolic process GO:0006521 0 0.198
neural precursor cell proliferation GO:0061351 75 0.197
Fly
organ formation GO:0048645 39 0.195
Fly
segmentation GO:0035282 207 0.194
Zebrafish Mouse
epithelial tube morphogenesis GO:0060562 88 0.192
Mouse
head development GO:0060322 135 0.189
Zebrafish Mouse Rat Fly
axonogenesis GO:0007409 290 0.189
Zebrafish
positive regulation of developmental process GO:0051094 143 0.189
Fly
dorsal ventral pattern formation GO:0009953 133 0.186
Fly
intracellular signal transduction GO:0035556 300 0.186
Mouse
epithelial tube formation GO:0072175 7 0.183
Mouse
larval locomotory behavior GO:0008345 27 0.181
Fly
hematopoietic progenitor cell differentiation GO:0002244 1 0.181
Rat
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.180
morphogenesis of embryonic epithelium GO:0016331 94 0.180
Mouse
cellular amine metabolic process GO:0044106 12 0.178
regulation of cellular amine metabolic process GO:0033238 3 0.176
epidermal cell differentiation GO:0009913 51 0.176
Mouse Worm
eye photoreceptor cell differentiation GO:0001754 145 0.175
Fly
peptidyl tyrosine phosphorylation GO:0018108 24 0.174
Mouse
proximal distal pattern formation GO:0009954 15 0.174
Mouse
gland development GO:0048732 191 0.173
Fly
cellular response to dna damage stimulus GO:0006974 223 0.172
Fly
regulation of cell proliferation GO:0042127 163 0.172
Human Fly
positive regulation of phosphate metabolic process GO:0045937 139 0.170
Zebrafish Mouse
embryonic organ development GO:0048568 50 0.169
Zebrafish
startle response GO:0001964 16 0.168
Fly
regulation of cellular ketone metabolic process GO:0010565 3 0.167
regulation of bmp signaling pathway GO:0030510 23 0.166
Mouse
regulation of neuron differentiation GO:0045664 103 0.166
Mouse Rat
compound eye photoreceptor cell differentiation GO:0001751 140 0.165
Fly
mitotic nuclear division GO:0007067 213 0.164
Fly
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 38 0.158
Mouse
positive regulation of cellular biosynthetic process GO:0031328 316 0.156
Mouse
segment specification GO:0007379 33 0.156
Zebrafish Mouse
transmission of nerve impulse GO:0019226 12 0.155
Mouse
negative regulation of cell differentiation GO:0045596 143 0.154
Human Zebrafish Mouse Rat
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.154
Mouse
organelle fission GO:0048285 340 0.153
Fly
regulation of peptidyl tyrosine phosphorylation GO:0050730 10 0.153
Mouse
salivary gland development GO:0007431 162 0.151
Fly
regionalization GO:0003002 416 0.150
Zebrafish Mouse Worm Fly
regulation of gliogenesis GO:0014013 11 0.149
Mouse
negative regulation of immune system process GO:0002683 50 0.148
Rat
regulation of stem cell proliferation GO:0072091 40 0.146
Fly
negative regulation of neurogenesis GO:0050768 53 0.146
Zebrafish Mouse Rat
dorsal ventral pattern formation imaginal disc GO:0007450 51 0.143
Fly
negative regulation of cellular biosynthetic process GO:0031327 277 0.143
Zebrafish Mouse Rat Fly
carboxylic acid metabolic process GO:0019752 92 0.143
gland morphogenesis GO:0022612 145 0.142
Fly
cell fate determination GO:0001709 91 0.140
Mouse Fly
positive regulation of cellular component organization GO:0051130 156 0.139
Fly
regulation of hematopoietic progenitor cell differentiation GO:1901532 1 0.139
Rat
cranial nerve development GO:0021545 1 0.139
Mouse
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.138
Mouse Rat Fly
dendrite morphogenesis GO:0048813 199 0.137
Fly
negative regulation of gliogenesis GO:0014014 6 0.133
Mouse
regulation of stem cell differentiation GO:2000736 14 0.130
Human
negative regulation of gene expression GO:0010629 387 0.130
Zebrafish Mouse Rat Worm Fly
regulation of transferase activity GO:0051338 58 0.130
Zebrafish
stem cell differentiation GO:0048863 117 0.128
Human Mouse Rat
immune system development GO:0002520 57 0.128
Rat
positive regulation of intracellular signal transduction GO:1902533 116 0.127
Mouse
wing disc pattern formation GO:0035222 66 0.126
Fly
organic acid metabolic process GO:0006082 103 0.124
regulation of notch signaling pathway GO:0008593 100 0.124
Mouse
response to hypoxia GO:0001666 53 0.123
Fly
neuronal action potential GO:0019228 10 0.122
Mouse
salivary gland morphogenesis GO:0007435 145 0.121
Fly
mesoderm development GO:0007498 78 0.121
Fly
protein complex biogenesis GO:0070271 201 0.120
Mouse
cellular ketone metabolic process GO:0042180 24 0.119
renal tubule development GO:0061326 64 0.119
Mouse
hemopoiesis GO:0030097 46 0.117
Rat
positive regulation of gene expression GO:0010628 290 0.117
Mouse
positive regulation of signal transduction GO:0009967 223 0.117
Mouse
positive regulation of biosynthetic process GO:0009891 316 0.116
Mouse
response to abiotic stimulus GO:0009628 341 0.116
Fly
cell proliferation GO:0008283 299 0.115
Human Fly
protein modification process GO:0036211 438 0.115
Zebrafish Mouse
regulation of response to stress GO:0080134 200 0.114
Fly
negative regulation of nervous system development GO:0051961 92 0.114
Zebrafish Mouse Rat
cell cell signaling involved in cell fate commitment GO:0045168 210 0.114
regulation of catalytic activity GO:0050790 185 0.112
Zebrafish
neurological system process GO:0050877 358 0.112
Mouse Fly
regulation of molecular function GO:0065009 217 0.112
Zebrafish
positive regulation of cell differentiation GO:0045597 64 0.111
Fly
positive regulation of cell communication GO:0010647 250 0.110
Mouse
positive regulation of multicellular organismal process GO:0051240 143 0.110
Fly
central nervous system development GO:0007417 201 0.110
Zebrafish Mouse Rat Fly
negative regulation of multicellular organismal process GO:0051241 142 0.109
Zebrafish Mouse Rat
immune system process GO:0002376 347 0.109
Rat
enzyme linked receptor protein signaling pathway GO:0007167 179 0.108
Mouse
axon development GO:0061564 297 0.107
Zebrafish
regulation of phosphate metabolic process GO:0019220 210 0.107
Zebrafish Mouse
cellular protein modification process GO:0006464 438 0.106
Zebrafish Mouse
peripheral nervous system neuron development GO:0048935 8 0.106
Zebrafish
peptidyl tyrosine modification GO:0018212 24 0.105
Mouse
cell division GO:0051301 248 0.103
Fly
regulation of mitotic cell cycle GO:0007346 190 0.103
Fly
protein complex assembly GO:0006461 200 0.102
Mouse
neuromuscular process GO:0050905 21 0.100
Fly
positive regulation of cellular protein metabolic process GO:0032270 118 0.100
Zebrafish Mouse
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.098
Mouse
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.098
Mouse
response to decreased oxygen levels GO:0036293 58 0.098
Fly
oxoacid metabolic process GO:0043436 103 0.096
regulation of cellular response to stress GO:0080135 89 0.096
Fly
regulation of nuclear division GO:0051783 58 0.094
Fly
macromolecular complex assembly GO:0065003 256 0.089
Mouse
axon ensheathment GO:0008366 10 0.085
Mouse
positive regulation of neural precursor cell proliferation GO:2000179 8 0.084
Fly
regulation of cell cycle process GO:0010564 181 0.084
Fly
organonitrogen compound metabolic process GO:1901564 318 0.083
stem cell development GO:0048864 79 0.083
Human Mouse Rat
positive regulation of cell proliferation GO:0008284 47 0.083
Human Fly
smoothened signaling pathway GO:0007224 49 0.083
Mouse
positive regulation of nucleic acid templated transcription GO:1903508 266 0.080
Mouse
positive regulation of protein serine threonine kinase activity GO:0071902 15 0.079
Zebrafish
negative regulation of transcription dna templated GO:0045892 237 0.079
Zebrafish Mouse Rat Fly
peripheral nervous system neuron differentiation GO:0048934 8 0.078
Zebrafish
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.077
positive regulation of phosphorus metabolic process GO:0010562 139 0.076
Zebrafish Mouse
positive regulation of catalytic activity GO:0043085 118 0.076
Zebrafish
regulation of protein kinase activity GO:0045859 51 0.073
Zebrafish
positive regulation of response to stimulus GO:0048584 323 0.073
Mouse
cell maturation GO:0048469 144 0.073
Mouse
protein phosphorylation GO:0006468 169 0.072
Zebrafish Mouse
developmental maturation GO:0021700 172 0.072
Mouse
negative regulation of biosynthetic process GO:0009890 277 0.071
Zebrafish Mouse Rat Fly
exocrine system development GO:0035272 162 0.071
Fly
positive regulation of mitotic cell cycle GO:0045931 34 0.070
Fly
regulation of cell cycle GO:0051726 291 0.070
Zebrafish Fly
positive regulation of neurogenesis GO:0050769 41 0.069
Fly
cell adhesion GO:0007155 136 0.069
Mouse
glial cell differentiation GO:0010001 35 0.069
Mouse Rat
cell fate commitment involved in pattern specification GO:0060581 31 0.067
Fly
regulation of cell division GO:0051302 72 0.067
Fly
renal tubule morphogenesis GO:0061333 44 0.065
Mouse
positive regulation of notch signaling pathway GO:0045747 34 0.065
Mouse
multicellular organismal signaling GO:0035637 12 0.064
Mouse
urogenital system development GO:0001655 72 0.064
Mouse
regulation of neural precursor cell proliferation GO:2000177 35 0.064
Fly
glial cell development GO:0021782 27 0.064
Mouse
humoral immune response GO:0006959 117 0.064
neuron projection guidance GO:0097485 241 0.064
skin development GO:0043588 65 0.063
Mouse Worm
spinal cord development GO:0021510 1 0.063
brain development GO:0007420 120 0.059
Zebrafish Mouse Rat Fly
cellular amino acid metabolic process GO:0006520 61 0.059
biological adhesion GO:0022610 138 0.059
Mouse
positive regulation of cell development GO:0010720 61 0.059
Fly
regulation of anatomical structure size GO:0090066 163 0.056
positive regulation of nervous system development GO:0051962 69 0.056
Fly
hematopoietic or lymphoid organ development GO:0048534 57 0.056
Rat
peptidyl amino acid modification GO:0018193 105 0.055
Mouse
regulation of membrane potential GO:0042391 35 0.055
Mouse
action potential GO:0001508 13 0.055
Mouse
phosphorylation GO:0016310 294 0.054
Zebrafish Mouse
ensheathment of neurons GO:0007272 10 0.050
Mouse
amine metabolic process GO:0009308 12 0.047
epithelial cell differentiation GO:0030855 322 0.047
Mouse Worm
positive regulation of cell cycle process GO:0090068 28 0.047
Fly
response to oxygen levels GO:0070482 59 0.045
Fly
positive regulation of protein phosphorylation GO:0001934 34 0.044
Zebrafish Mouse
glandular epithelial cell differentiation GO:0002067 1 0.044
regulation of protein serine threonine kinase activity GO:0071900 25 0.044
Zebrafish
digestive tract morphogenesis GO:0048546 127 0.043
brain morphogenesis GO:0048854 16 0.042
Fly
negative regulation of cell cycle process GO:0010948 109 0.041
positive regulation of protein kinase activity GO:0045860 25 0.041
Zebrafish
regulation of protein metabolic process GO:0051246 256 0.040
Zebrafish Mouse
wing disc dorsal ventral pattern formation GO:0048190 47 0.040
Fly
neuron fate specification GO:0048665 12 0.039
embryonic organ morphogenesis GO:0048562 5 0.039
Zebrafish
positive regulation of protein metabolic process GO:0051247 128 0.039
Zebrafish Mouse
appendage development GO:0048736 401 0.038
regulation of protein phosphorylation GO:0001932 64 0.037
Zebrafish Mouse
regulation of phosphorylation GO:0042325 147 0.036
Zebrafish Mouse
positive regulation of phosphorylation GO:0042327 87 0.036
Zebrafish Mouse
positive regulation of neuroblast proliferation GO:0002052 7 0.035
Fly
regulation of immune system process GO:0002682 176 0.035
Rat
cell death GO:0008219 279 0.034
regulation of cell death GO:0010941 173 0.034
regulation of neuron projection development GO:0010975 69 0.034
glial cell proliferation GO:0014009 13 0.034
regulation of epithelial cell differentiation GO:0030856 4 0.034
imaginal disc derived appendage development GO:0048737 399 0.034
anterior posterior axis specification GO:0009948 109 0.033
muscle structure development GO:0061061 224 0.033
central nervous system neuron differentiation GO:0021953 8 0.033
Rat
regulation of phosphorus metabolic process GO:0051174 210 0.033
Zebrafish Mouse
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.033
positive regulation of organelle organization GO:0010638 65 0.032
Fly
positive regulation of stem cell proliferation GO:2000648 8 0.032
Fly
neuroblast fate specification GO:0014018 2 0.032
positive regulation of protein modification process GO:0031401 58 0.031
Zebrafish Mouse
regulation of protein modification process GO:0031399 112 0.031
Zebrafish Mouse
regulation of cell morphogenesis GO:0022604 163 0.030
single organism cellular localization GO:1902580 180 0.030
endoderm development GO:0007492 6 0.030
Zebrafish
regulation of reproductive process GO:2000241 54 0.029
negative regulation of neuron differentiation GO:0045665 16 0.028
Mouse Rat
immune response GO:0006955 246 0.028
regulation of cellular protein metabolic process GO:0032268 243 0.028
Zebrafish Mouse
establishment of localization in cell GO:0051649 402 0.027
negative regulation of notch signaling pathway GO:0045746 41 0.027
regulation of kinase activity GO:0043549 53 0.027
Zebrafish
developmental cell growth GO:0048588 52 0.027
organelle localization GO:0051640 148 0.027
spinal cord patterning GO:0021511 1 0.026
stem cell fate determination GO:0048867 15 0.026
macromolecule catabolic process GO:0009057 161 0.026
taxis GO:0042330 304 0.025
negative regulation of cell communication GO:0010648 223 0.025
positive regulation of kinase activity GO:0033674 25 0.025
Zebrafish
renal system development GO:0072001 72 0.025
Mouse
axon guidance GO:0007411 233 0.024
regulation of glial cell proliferation GO:0060251 11 0.023
death GO:0016265 284 0.023
imaginal disc derived appendage morphogenesis GO:0035114 395 0.023
apoptotic process involved in morphogenesis GO:0060561 3 0.023
negative regulation of glial cell proliferation GO:0060253 6 0.023
negative regulation of response to stimulus GO:0048585 258 0.022
regulation of antimicrobial peptide production GO:0002784 44 0.022
stem cell fate specification GO:0048866 2 0.021
negative regulation of cell cycle GO:0045786 116 0.021
wing disc morphogenesis GO:0007472 344 0.021
positive regulation of transferase activity GO:0051347 26 0.021
Zebrafish
spinal cord dorsal ventral patterning GO:0021513 1 0.020
stem cell fate commitment GO:0048865 25 0.020
response to lipopolysaccharide GO:0032496 4 0.020
carbohydrate derivative metabolic process GO:1901135 217 0.020
cellular catabolic process GO:0044248 372 0.020
programmed cell death GO:0012501 257 0.020
regulation of multi organism process GO:0043900 131 0.020
body morphogenesis GO:0010171 2 0.020
single organism biosynthetic process GO:0044711 206 0.019
camera type eye morphogenesis GO:0048593 2 0.019
digestive system development GO:0055123 149 0.019
organic substance transport GO:0071702 257 0.019
intracellular mrna localization involved in pattern specification process GO:0060810 56 0.019
defense response to other organism GO:0098542 225 0.018
neuroblast fate commitment GO:0014017 19 0.018
cell migration GO:0016477 238 0.018
epithelial cell development GO:0002064 274 0.018
anterior posterior axis specification embryo GO:0008595 103 0.017
response to wounding GO:0009611 94 0.017
muscle cell development GO:0055001 50 0.017
eye photoreceptor cell fate commitment GO:0042706 37 0.017
regulation of cellular catabolic process GO:0031329 157 0.017
positive regulation of cell cycle GO:0045787 43 0.017
Zebrafish Fly
regulation of catabolic process GO:0009894 170 0.017
regulation of cellular amide metabolic process GO:0034248 39 0.017
somatic stem cell division GO:0048103 37 0.017
embryonic hindgut morphogenesis GO:0048619 48 0.017
digestive tract development GO:0048565 149 0.016
mesenchymal cell differentiation GO:0048762 1 0.016
compound eye photoreceptor fate commitment GO:0001752 36 0.016
negative regulation of signal transduction GO:0009968 206 0.016
retina development in camera type eye GO:0060041 4 0.016
organic substance catabolic process GO:1901575 308 0.015
hindgut morphogenesis GO:0007442 58 0.015
regulation of antimicrobial peptide biosynthetic process GO:0002805 38 0.015
post embryonic appendage morphogenesis GO:0035120 385 0.015
negative regulation of signaling GO:0023057 219 0.015
regulation of programmed cell death GO:0043067 152 0.015
response to oxygen containing compound GO:1901700 200 0.015
chaeta development GO:0022416 97 0.014
vesicle mediated transport GO:0016192 381 0.014
localization of cell GO:0051674 257 0.014
intracellular transport GO:0046907 228 0.014
cellular macromolecule catabolic process GO:0044265 136 0.014
neuroepithelial cell differentiation GO:0060563 6 0.014
rna localization GO:0006403 115 0.014
regulation of hydrolase activity GO:0051336 97 0.014
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.014
regulation of anatomical structure morphogenesis GO:0022603 242 0.014
Mouse
axis specification GO:0009798 167 0.014
regulation of jak stat cascade GO:0046425 43 0.014
Mouse
neuroblast fate determination GO:0007400 12 0.014
bolwig s organ development GO:0055034 8 0.014
cellular macromolecule localization GO:0070727 220 0.014
regulation of cell cycle phase transition GO:1901987 130 0.014
antimicrobial peptide biosynthetic process GO:0002777 38 0.013
neuroblast differentiation GO:0014016 29 0.013
locomotor rhythm GO:0045475 56 0.013
alternative mrna splicing via spliceosome GO:0000380 60 0.013
reproductive system development GO:0061458 74 0.013
mitotic dna damage checkpoint GO:0044773 74 0.013
axon extension involved in axon guidance GO:0048846 10 0.013
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.013
developmental programmed cell death GO:0010623 138 0.013
mitochondrion organization GO:0007005 65 0.013
mitotic cell cycle checkpoint GO:0007093 88 0.013
central nervous system neuron development GO:0021954 8 0.012
apoptotic process GO:0006915 159 0.012
gastrulation GO:0007369 70 0.012
catabolic process GO:0009056 409 0.012
neuron projection extension GO:1990138 32 0.012
small gtpase mediated signal transduction GO:0007264 88 0.012
regulation of localization GO:0032879 275 0.012
heart development GO:0007507 82 0.012
single organism membrane organization GO:0044802 93 0.012
regulation of alternative mrna splicing via spliceosome GO:0000381 60 0.012
regulation of developmental growth GO:0048638 174 0.012
establishment of protein localization GO:0045184 163 0.011
posttranscriptional gene silencing GO:0016441 46 0.011
regulation of axonogenesis GO:0050770 32 0.011
regulation of mapk cascade GO:0043408 92 0.011
regulation of cellular component size GO:0032535 98 0.011
positive regulation of neuron differentiation GO:0045666 26 0.011
regulation of small gtpase mediated signal transduction GO:0051056 93 0.011
embryonic pattern specification GO:0009880 174 0.011
Zebrafish
steroid catabolic process GO:0006706 1 0.011
response to other organism GO:0051707 293 0.011
organonitrogen compound biosynthetic process GO:1901566 117 0.011
antimicrobial humoral response GO:0019730 99 0.011
regulation of embryonic development GO:0045995 68 0.011
Mouse
rna processing GO:0006396 147 0.011
neuroblast division GO:0055057 35 0.011
negative regulation of cell cycle phase transition GO:1901988 103 0.011
regulation of mitotic cell cycle phase transition GO:1901990 130 0.011
nucleus organization GO:0006997 45 0.011
proteolysis GO:0006508 192 0.011
imaginal disc derived wing morphogenesis GO:0007476 337 0.011
cell cycle arrest GO:0007050 4 0.011
neuron recognition GO:0008038 101 0.011
wound healing GO:0042060 75 0.011
photoreceptor cell fate commitment GO:0046552 41 0.011
response to alcohol GO:0097305 95 0.011
muscle organ development GO:0007517 127 0.010
positive regulation of cell division GO:0051781 16 0.010
Fly
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 73 0.010
ribonucleotide metabolic process GO:0009259 145 0.010
regulation of axon extension GO:0030516 8 0.010
protein localization GO:0008104 284 0.010
dna metabolic process GO:0006259 227 0.010
epithelial cell proliferation involved in malpighian tubule morphogenesis GO:0061331 11 0.010
neural retina development GO:0003407 4 0.010
embryonic axis specification GO:0000578 107 0.010
meiotic cell cycle process GO:1903046 132 0.010
meiotic nuclear division GO:0007126 151 0.010
membrane organization GO:0061024 112 0.010

HLHm3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
bone development disease DOID:0080006 0 0.569
Human
bone disease DOID:0080001 0 0.569
Human
disease of anatomical entity DOID:7 0 0.569
Human
dysostosis DOID:1934 0 0.569
Human
musculoskeletal system disease DOID:17 0 0.569
Human
connective tissue disease DOID:65 0 0.569
Human
spondylocostal dysostosis DOID:0050568 0 0.164
Human
sensory system disease DOID:0050155 0 0.010
eye and adnexa disease DOID:1492 0 0.010
nervous system disease DOID:863 0 0.010