Drosophila melanogaster

40 known processes

soti (Dmel_CG8489)

scotti

(Aliases: Dmel\CG8489,CG8489)

soti biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
spermatid development GO:0007286 98 0.930
spermatid differentiation GO:0048515 114 0.835
sperm individualization GO:0007291 48 0.707
male gamete generation GO:0048232 201 0.706
spermatogenesis GO:0007283 200 0.668
cellularization GO:0007349 90 0.550
lateral inhibition GO:0046331 206 0.184
organelle assembly GO:0070925 198 0.172
chromatin modification GO:0016568 147 0.092
nucleus organization GO:0006997 45 0.087
regulation of response to stress GO:0080134 200 0.084
cell cell signaling involved in cell fate commitment GO:0045168 210 0.083
chromatin organization GO:0006325 207 0.074
positive regulation of cysteine type endopeptidase activity GO:2001056 24 0.074
chromosome organization GO:0051276 360 0.056
immune system process GO:0002376 347 0.054
programmed cell death GO:0012501 257 0.053
protein localization GO:0008104 284 0.051
response to external biotic stimulus GO:0043207 293 0.047
negative regulation of gene expression epigenetic GO:0045814 77 0.047
positive regulation of endopeptidase activity GO:0010950 26 0.044
endocytosis GO:0006897 310 0.044
dna conformation change GO:0071103 105 0.043
regulation of cell morphogenesis GO:0022604 163 0.042
positive regulation of proteolysis GO:0045862 52 0.041
small molecule metabolic process GO:0044281 305 0.040
posttranscriptional regulation of gene expression GO:0010608 145 0.039
mating behavior GO:0007617 106 0.038
cytokinesis GO:0000910 90 0.037
developmental programmed cell death GO:0010623 138 0.037
organophosphate metabolic process GO:0019637 195 0.037
defense response to other organism GO:0098542 225 0.035
single organism biosynthetic process GO:0044711 206 0.035
protein dna complex subunit organization GO:0071824 86 0.035
intracellular signal transduction GO:0035556 300 0.034
spindle organization GO:0007051 253 0.034
regulation of protein metabolic process GO:0051246 256 0.033
cell division GO:0051301 248 0.033
defense response GO:0006952 300 0.033
regulation of multicellular organismal development GO:2000026 414 0.032
defense response to bacterium GO:0042742 178 0.032
centrosome organization GO:0051297 163 0.031
regulation of catalytic activity GO:0050790 185 0.031
cellular catabolic process GO:0044248 372 0.030
regulation of immune response GO:0050776 118 0.030
negative regulation of cellular metabolic process GO:0031324 382 0.030
gene silencing GO:0016458 138 0.030
negative regulation of response to stimulus GO:0048585 258 0.029
positive regulation of cell communication GO:0010647 250 0.028
single organism cellular localization GO:1902580 180 0.028
vesicle mediated transport GO:0016192 381 0.028
negative regulation of developmental process GO:0051093 201 0.027
regulation of anatomical structure morphogenesis GO:0022603 242 0.027
regulation of nervous system development GO:0051960 248 0.027
cilium morphogenesis GO:0060271 39 0.026
regulation of cellular amino acid metabolic process GO:0006521 0 0.026
endomembrane system organization GO:0010256 119 0.026
single organism behavior GO:0044708 391 0.025
oxoacid metabolic process GO:0043436 103 0.025
histolysis GO:0007559 102 0.025
immune response GO:0006955 246 0.025
activation of cysteine type endopeptidase activity GO:0097202 17 0.024
nucleotide metabolic process GO:0009117 161 0.024
regulation of cell differentiation GO:0045595 302 0.024
establishment of localization in cell GO:0051649 402 0.024
chromatin remodeling GO:0006338 72 0.024
death GO:0016265 284 0.024
regulation of cellular protein metabolic process GO:0032268 243 0.024
cytoskeleton dependent cytokinesis GO:0061640 81 0.024
microtubule organizing center organization GO:0031023 168 0.024
regulation of cellular ketone metabolic process GO:0010565 3 0.024
organonitrogen compound metabolic process GO:1901564 318 0.023
regulation of cysteine type endopeptidase activity GO:2000116 27 0.023
mrna metabolic process GO:0016071 124 0.023
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.023
organic substance catabolic process GO:1901575 308 0.023
catabolic process GO:0009056 409 0.022
cell proliferation GO:0008283 299 0.022
regulation of multi organism process GO:0043900 131 0.022
regulation of cell development GO:0060284 215 0.021
multi organism behavior GO:0051705 175 0.021
negative regulation of rna biosynthetic process GO:1902679 240 0.021
eye morphogenesis GO:0048592 260 0.021
carboxylic acid metabolic process GO:0019752 92 0.020
rna processing GO:0006396 147 0.020
cellular macromolecule catabolic process GO:0044265 136 0.020
positive regulation of programmed cell death GO:0043068 62 0.020
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.020
regulation of molecular function GO:0065009 217 0.020
zymogen activation GO:0031638 20 0.019
regulation of catabolic process GO:0009894 170 0.019
body morphogenesis GO:0010171 2 0.019
sensory organ morphogenesis GO:0090596 260 0.019
erbb signaling pathway GO:0038127 58 0.019
regulation of developmental growth GO:0048638 174 0.019
regulation of neurogenesis GO:0050767 158 0.019
negative regulation of cell differentiation GO:0045596 143 0.018
regulation of immune system process GO:0002682 176 0.018
regulation of proteolysis GO:0030162 87 0.018
single organism membrane organization GO:0044802 93 0.018
regulation of gene expression epigenetic GO:0040029 128 0.018
positive regulation of molecular function GO:0044093 136 0.018
forebrain development GO:0030900 2 0.018
cilium assembly GO:0042384 38 0.018
actin cytoskeleton organization GO:0030036 206 0.018
positive regulation of catalytic activity GO:0043085 118 0.018
positive regulation of developmental process GO:0051094 143 0.018
sperm axoneme assembly GO:0007288 13 0.018
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.017
negative regulation of cellular biosynthetic process GO:0031327 277 0.017
cytoplasmic transport GO:0016482 130 0.017
negative regulation of gene expression GO:0010629 387 0.017
organic acid metabolic process GO:0006082 103 0.017
nucleosome organization GO:0034728 59 0.017
cellular macromolecule localization GO:0070727 220 0.017
cell death GO:0008219 279 0.017
macromolecular complex assembly GO:0065003 256 0.017
centrosome cycle GO:0007098 137 0.016
purine nucleotide metabolic process GO:0006163 146 0.016
microtubule bundle formation GO:0001578 27 0.016
response to glucose GO:0009749 2 0.016
regulation of cellular amine metabolic process GO:0033238 3 0.016
regulation of phosphate metabolic process GO:0019220 210 0.016
phagocytosis GO:0006909 215 0.016
intracellular transport GO:0046907 228 0.016
nucleobase containing small molecule metabolic process GO:0055086 174 0.016
regulation of phosphorus metabolic process GO:0051174 210 0.016
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.015
nucleoside phosphate metabolic process GO:0006753 162 0.015
positive regulation of response to stimulus GO:0048584 323 0.015
regulation of cellular localization GO:0060341 136 0.015
establishment or maintenance of cell polarity GO:0007163 167 0.015
photoreceptor cell differentiation GO:0046530 170 0.015
cilium organization GO:0044782 41 0.015
regulation of gene silencing GO:0060968 63 0.015
sterol homeostasis GO:0055092 4 0.015
single organism intracellular transport GO:1902582 207 0.015
developmental growth GO:0048589 280 0.015
negative regulation of biosynthetic process GO:0009890 277 0.015
positive regulation of macromolecule metabolic process GO:0010604 405 0.015
response to extracellular stimulus GO:0009991 116 0.015
positive regulation of cellular biosynthetic process GO:0031328 316 0.015
single organism catabolic process GO:0044712 228 0.015
regulation of cell cycle GO:0051726 291 0.015
salivary gland development GO:0007431 162 0.015
ribose phosphate metabolic process GO:0019693 145 0.015
compound eye development GO:0048749 307 0.015
enzyme linked receptor protein signaling pathway GO:0007167 179 0.015
positive regulation of signal transduction GO:0009967 223 0.015
response to other organism GO:0051707 293 0.015
positive regulation of biosynthetic process GO:0009891 316 0.014
autophagic cell death GO:0048102 83 0.014
antimicrobial humoral response GO:0019730 99 0.014
dna metabolic process GO:0006259 227 0.014
regulation of intracellular signal transduction GO:1902531 236 0.014
chromatin silencing GO:0006342 76 0.014
response to hexose GO:0009746 3 0.014
organelle localization GO:0051640 148 0.014
eye development GO:0001654 323 0.014
purine containing compound metabolic process GO:0072521 155 0.014
regionalization GO:0003002 416 0.014
purine ribonucleotide metabolic process GO:0009150 145 0.014
atp dependent chromatin remodeling GO:0043044 22 0.014
innate immune response GO:0045087 144 0.014
cellular ketone metabolic process GO:0042180 24 0.014
phosphorylation GO:0016310 294 0.013
positive regulation of cellular protein metabolic process GO:0032270 118 0.013
rna splicing GO:0008380 83 0.013
positive regulation of signaling GO:0023056 243 0.013
response to organic substance GO:0010033 284 0.013
cellular protein localization GO:0034613 160 0.013
camera type eye development GO:0043010 4 0.013
organophosphate biosynthetic process GO:0090407 46 0.013
proteolysis GO:0006508 192 0.013
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.013
rna localization GO:0006403 115 0.013
gland development GO:0048732 191 0.013
positive regulation of protein metabolic process GO:0051247 128 0.013
ubiquitin dependent protein catabolic process GO:0006511 78 0.013
response to biotic stimulus GO:0009607 294 0.013
negative regulation of multicellular organismal process GO:0051241 142 0.013
negative regulation of nervous system development GO:0051961 92 0.013
protein modification process GO:0036211 438 0.013
cellular response to dna damage stimulus GO:0006974 223 0.012
eye photoreceptor cell differentiation GO:0001754 145 0.012
salivary gland morphogenesis GO:0007435 145 0.012
negative regulation of rna metabolic process GO:0051253 251 0.012
cellular amino acid metabolic process GO:0006520 61 0.012
axis specification GO:0009798 167 0.012
male courtship behavior GO:0008049 63 0.012
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.012
gland morphogenesis GO:0022612 145 0.012
limb morphogenesis GO:0035108 1 0.012
salivary gland cell autophagic cell death GO:0035071 83 0.012
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.012
lipid metabolic process GO:0006629 121 0.012
mitotic sister chromatid segregation GO:0000070 87 0.012
protein transport GO:0015031 155 0.011
organic substance transport GO:0071702 257 0.011
mitotic spindle organization GO:0007052 220 0.011
small gtpase mediated signal transduction GO:0007264 88 0.011
adult behavior GO:0030534 137 0.011
negative regulation of cellular protein metabolic process GO:0032269 85 0.011
axoneme assembly GO:0035082 18 0.011
positive regulation of peptidase activity GO:0010952 29 0.011
regulation of alternative mrna splicing via spliceosome GO:0000381 60 0.011
negative regulation of cell communication GO:0010648 223 0.011
stem cell proliferation GO:0072089 88 0.011
cell cycle checkpoint GO:0000075 95 0.011
embryo development ending in birth or egg hatching GO:0009792 152 0.011
response to starvation GO:0042594 97 0.011
regulation of mrna metabolic process GO:1903311 72 0.011
lipid biosynthetic process GO:0008610 46 0.011
endoplasmic reticulum organization GO:0007029 13 0.011
appendage morphogenesis GO:0035107 397 0.011
regulation of cellular component size GO:0032535 98 0.011
positive regulation of phosphorus metabolic process GO:0010562 139 0.011
regulation of anatomical structure size GO:0090066 163 0.011
regulation of hydrolase activity GO:0051336 97 0.010
central nervous system development GO:0007417 201 0.010
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 25 0.010
protein complex assembly GO:0006461 200 0.010
positive regulation of cellular amine metabolic process GO:0033240 0 0.010
nucleoside triphosphate metabolic process GO:0009141 120 0.010
response to nutrient levels GO:0031667 114 0.010
lipid modification GO:0030258 24 0.010
actin filament organization GO:0007015 126 0.010
regulation of localization GO:0032879 275 0.010
organonitrogen compound biosynthetic process GO:1901566 117 0.010

soti disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.018
cancer DOID:162 0 0.014
disease of cellular proliferation DOID:14566 0 0.014
disease of metabolism DOID:0014667 0 0.010
inherited metabolic disorder DOID:655 0 0.010