Drosophila melanogaster

340 known processes

Rac2 (Dmel_CG8556)

CG8556 gene product from transcript CG8556-RA

(Aliases: DRac2,rac2,D-Rac2,CG8556,Drac2,Drac1b,Dmel\CG8556,D-Rac 2,Rac-2,DmRAC2,Rac1b,DRacB,RacB,Rac GTPase,Rac)

Rac2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
myoblast fusion GO:0007520 43 0.999
Fly
striated muscle cell differentiation GO:0051146 90 0.986
Fly
embryonic morphogenesis GO:0048598 206 0.971
melanin metabolic process GO:0006582 47 0.966
actin filament based process GO:0030029 220 0.955
encapsulation of foreign target GO:0035010 38 0.952
syncytium formation GO:0006949 43 0.948
Fly
immune response GO:0006955 246 0.947
myotube differentiation GO:0014902 46 0.944
Fly
immune system process GO:0002376 347 0.943
muscle structure development GO:0061061 224 0.925
hemocyte differentiation GO:0042386 38 0.922
Fly
embryonic development via the syncytial blastoderm GO:0001700 148 0.922
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.915
Rat
regulation of neurogenesis GO:0050767 158 0.912
g protein coupled receptor signaling pathway GO:0007186 136 0.879
Mouse
actin filament organization GO:0007015 126 0.852
actin cytoskeleton organization GO:0030036 206 0.827
melanization defense response GO:0035006 45 0.818
melanotic encapsulation of foreign target GO:0035011 30 0.810
organic hydroxy compound metabolic process GO:1901615 83 0.803
ventral cord development GO:0007419 16 0.803
Fly
single organism behavior GO:0044708 391 0.779
skeletal muscle organ development GO:0060538 48 0.773
regulation of molecular function GO:0065009 217 0.761
Mouse Fly
regulation of cell differentiation GO:0045595 302 0.728
cell projection assembly GO:0030031 94 0.717
mesodermal cell migration GO:0008078 7 0.705
Fly
syncytium formation by plasma membrane fusion GO:0000768 43 0.701
Fly
muscle cell differentiation GO:0042692 103 0.696
Fly
regulation of catalytic activity GO:0050790 185 0.693
Mouse Fly
cell migration GO:0016477 238 0.677
regulation of cell morphogenesis GO:0022604 163 0.677
regulation of cell development GO:0060284 215 0.666
negative regulation of signaling GO:0023057 219 0.663
localization of cell GO:0051674 257 0.646
muscle attachment GO:0016203 36 0.631
immune effector process GO:0002252 98 0.626
imaginal disc derived appendage morphogenesis GO:0035114 395 0.618
Fly
regulation of hemocyte differentiation GO:0045610 22 0.617
Fly
regulation of cell shape GO:0008360 113 0.614
negative regulation of signal transduction GO:0009968 206 0.613
small molecule metabolic process GO:0044281 305 0.595
negative regulation of response to stimulus GO:0048585 258 0.592
innate immune response GO:0045087 144 0.581
neuron projection guidance GO:0097485 241 0.579
Mouse Worm Fly
muscle organ development GO:0007517 127 0.578
positive regulation of signaling GO:0023056 243 0.540
regulation of protein metabolic process GO:0051246 256 0.538
Human Fly
regulation of multicellular organismal development GO:2000026 414 0.533
positive regulation of phosphorylation GO:0042327 87 0.531
Human Mouse Fly
regulation of peptidase activity GO:0052547 39 0.524
wing disc morphogenesis GO:0007472 344 0.520
Fly
regulation of anatomical structure morphogenesis GO:0022603 242 0.519
cortical actin cytoskeleton organization GO:0030866 24 0.515
Fly
digestive tract development GO:0048565 149 0.511
Fly
positive regulation of developmental process GO:0051094 143 0.499
Human Worm
tube development GO:0035295 244 0.492
positive regulation of macromolecule metabolic process GO:0010604 405 0.486
Human Rat Fly
positive regulation of cell proliferation GO:0008284 47 0.486
Mouse
positive regulation of cellular biosynthetic process GO:0031328 316 0.485
Rat
positive regulation of cell differentiation GO:0045597 64 0.484
Human
appendage development GO:0048736 401 0.479
Fly
synapse organization GO:0050808 196 0.469
Fly
dendrite morphogenesis GO:0048813 199 0.457
Mouse Fly
cellular protein modification process GO:0006464 438 0.451
Human Fly
apoptotic cell clearance GO:0043277 14 0.450
Mouse Worm
multi organism behavior GO:0051705 175 0.449
regulation of programmed cell death GO:0043067 152 0.448
positive regulation of transcription dna templated GO:0045893 266 0.443
defense response GO:0006952 300 0.431
organic acid metabolic process GO:0006082 103 0.427
intracellular signal transduction GO:0035556 300 0.422
imaginal disc derived wing morphogenesis GO:0007476 337 0.416
Fly
phenol containing compound metabolic process GO:0018958 57 0.413
regulation of map kinase activity GO:0043405 17 0.406
epithelial cell differentiation GO:0030855 322 0.405
regulation of mapk cascade GO:0043408 92 0.399
positive regulation of cellular protein metabolic process GO:0032270 118 0.391
Human Fly
regulation of filopodium assembly GO:0051489 24 0.391
Fly
regulation of endopeptidase activity GO:0052548 36 0.389
immune system development GO:0002520 57 0.387
ovarian follicle cell development GO:0030707 248 0.383
carboxylic acid metabolic process GO:0019752 92 0.375
synaptic transmission GO:0007268 288 0.373
Fly
mapk cascade GO:0000165 107 0.366
regulation of response to external stimulus GO:0032101 115 0.360
Human Mouse
cell division GO:0051301 248 0.339
Fly
tube morphogenesis GO:0035239 191 0.336
dendrite development GO:0016358 204 0.331
Mouse Fly
regulation of protein serine threonine kinase activity GO:0071900 25 0.331
Fly
regulation of phosphate metabolic process GO:0019220 210 0.329
Human Mouse Fly
regulation of response to wounding GO:1903034 19 0.327
gland development GO:0048732 191 0.326
positive regulation of molecular function GO:0044093 136 0.323
Mouse Fly
gliogenesis GO:0042063 80 0.319
Fly
response to external biotic stimulus GO:0043207 293 0.318
regulation of intracellular signal transduction GO:1902531 236 0.307
protein phosphorylation GO:0006468 169 0.301
Human Fly
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.299
regulation of phosphatidylinositol 3 kinase activity GO:0043551 2 0.299
Mouse
imaginal disc derived appendage development GO:0048737 399 0.299
Fly
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.297
protein modification process GO:0036211 438 0.296
Human Fly
regulation of cell death GO:0010941 173 0.295
visceral muscle development GO:0007522 14 0.293
regulation of protein modification process GO:0031399 112 0.290
Human Fly
negative regulation of cell communication GO:0010648 223 0.290
heart development GO:0007507 82 0.290
regulation of immune system process GO:0002682 176 0.286
Human Zebrafish Mouse Fly
negative regulation of molecular function GO:0044092 51 0.285
cell motility GO:0048870 251 0.284
positive regulation of response to stimulus GO:0048584 323 0.281
regulation of cytoskeleton organization GO:0051493 89 0.280
Human Mouse Fly
single organism cell adhesion GO:0098602 47 0.271
Human Mouse
response to wounding GO:0009611 94 0.271
regulation of response to stress GO:0080134 200 0.264
positive regulation of phosphorus metabolic process GO:0010562 139 0.259
Human Mouse Fly
cell proliferation GO:0008283 299 0.259
Mouse Rat Fly
positive regulation of phosphate metabolic process GO:0045937 139 0.258
Human Mouse Fly
response to bacterium GO:0009617 198 0.257
cardiovascular system development GO:0072358 82 0.256
regulation of proteolysis GO:0030162 87 0.256
post embryonic appendage morphogenesis GO:0035120 385 0.255
Fly
positive regulation of biosynthetic process GO:0009891 316 0.250
Rat
striated muscle cell development GO:0055002 50 0.250
Fly
actin filament bundle organization GO:0061572 28 0.245
negative regulation of apoptotic process GO:0043066 63 0.245
phosphorylation GO:0016310 294 0.239
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.235
Rat
peptidyl tyrosine phosphorylation GO:0018108 24 0.234
response to nutrient levels GO:0031667 114 0.231
cellular amino acid metabolic process GO:0006520 61 0.228
cortical cytoskeleton organization GO:0030865 29 0.227
Fly
immune response regulating signaling pathway GO:0002764 2 0.227
regulation of cellular protein metabolic process GO:0032268 243 0.224
Human Fly
regulation of phosphorus metabolic process GO:0051174 210 0.223
Human Mouse Fly
rho protein signal transduction GO:0007266 14 0.221
axon development GO:0061564 297 0.219
morphogenesis of an epithelium GO:0002009 276 0.217
synaptic growth at neuromuscular junction GO:0051124 119 0.216
Fly
myotube cell development GO:0014904 3 0.212
positive regulation of protein phosphorylation GO:0001934 34 0.202
Human Fly
somatic muscle development GO:0007525 66 0.200
response to biotic stimulus GO:0009607 294 0.200
ameboidal type cell migration GO:0001667 151 0.199
Fly
positive regulation of lipid metabolic process GO:0045834 4 0.198
Mouse
tissue migration GO:0090130 155 0.198
Fly
positive regulation of cell communication GO:0010647 250 0.196
negative regulation of endopeptidase activity GO:0010951 11 0.196
axon midline choice point recognition GO:0016199 26 0.194
Fly
regulation of cellular amino acid metabolic process GO:0006521 0 0.193
actomyosin structure organization GO:0031032 56 0.192
Human
regulation of immune response GO:0050776 118 0.192
enzyme linked receptor protein signaling pathway GO:0007167 179 0.192
positive regulation of mapk cascade GO:0043410 63 0.191
negative regulation of catalytic activity GO:0043086 42 0.190
response to starvation GO:0042594 97 0.187
reproductive behavior GO:0019098 122 0.186
lamellipodium assembly GO:0030032 21 0.184
axonogenesis GO:0007409 290 0.181
morphogenesis of embryonic epithelium GO:0016331 94 0.181
adherens junction organization GO:0034332 27 0.180
regulation of synapse structure and activity GO:0050803 128 0.179
Fly
cell cell signaling involved in cell fate commitment GO:0045168 210 0.177
biological adhesion GO:0022610 138 0.176
Human Mouse
vesicle mediated transport GO:0016192 381 0.175
positive regulation of protein metabolic process GO:0051247 128 0.175
Human Fly
mucosal immune response GO:0002385 10 0.175
positive regulation of immune system process GO:0002684 68 0.175
Human Zebrafish Mouse
appendage morphogenesis GO:0035107 397 0.174
Fly
ras protein signal transduction GO:0007265 88 0.174
response to extracellular stimulus GO:0009991 116 0.170
regulation of kinase activity GO:0043549 53 0.166
Mouse Fly
cell growth GO:0016049 108 0.163
regulation of cell proliferation GO:0042127 163 0.162
Mouse
regulation of organelle organization GO:0033043 196 0.161
Human Mouse Fly
response to hydrogen peroxide GO:0042542 11 0.158
organonitrogen compound metabolic process GO:1901564 318 0.158
glial cell migration GO:0008347 31 0.157
Fly
response to endogenous stimulus GO:0009719 119 0.157
regulation of hydrolase activity GO:0051336 97 0.156
extracellular matrix disassembly GO:0022617 4 0.155
substrate adhesion dependent cell spreading GO:0034446 2 0.153
Human Mouse
positive regulation of cell death GO:0010942 69 0.151
cellular response to dna damage stimulus GO:0006974 223 0.149
Fly
ovarian follicle cell migration GO:0007297 121 0.149
Fly
regulation of cell cycle GO:0051726 291 0.149
Fly
hemopoiesis GO:0030097 46 0.149
digestive tract morphogenesis GO:0048546 127 0.148
Fly
dna replication GO:0006260 48 0.148
Rat
catabolic process GO:0009056 409 0.147
circulatory system development GO:0072359 82 0.146
epithelial cell migration GO:0010631 148 0.146
Fly
negative regulation of cell death GO:0060548 81 0.145
gastrulation GO:0007369 70 0.144
Fly
positive regulation of gene expression GO:0010628 290 0.141
regulation of phosphorylation GO:0042325 147 0.138
Human Mouse Fly
pigment metabolic process GO:0042440 84 0.138
regulation of transferase activity GO:0051338 58 0.137
Mouse Fly
muscle tissue development GO:0060537 30 0.136
hindgut morphogenesis GO:0007442 58 0.134
regulation of neuron differentiation GO:0045664 103 0.132
hindgut development GO:0061525 58 0.129
response to abiotic stimulus GO:0009628 341 0.126
Mouse
regulation of cellular amine metabolic process GO:0033238 3 0.126
positive regulation of cell development GO:0010720 61 0.125
Human
positive regulation of signal transduction GO:0009967 223 0.124
nucleobase containing small molecule metabolic process GO:0055086 174 0.124
gland morphogenesis GO:0022612 145 0.123
regionalization GO:0003002 416 0.123
defense response to bacterium GO:0042742 178 0.121
developmental maturation GO:0021700 172 0.120
anatomical structure homeostasis GO:0060249 97 0.116
Rat
salivary gland development GO:0007431 162 0.115
oxoacid metabolic process GO:0043436 103 0.113
chemotaxis GO:0006935 249 0.113
Human Mouse Rat Worm Fly
response to organic substance GO:0010033 284 0.112
regulation of protein phosphorylation GO:0001932 64 0.112
Human Fly
programmed cell death GO:0012501 257 0.112
hemocyte migration GO:0035099 19 0.111
defense response to other organism GO:0098542 225 0.109
columnar cuboidal epithelial cell development GO:0002066 249 0.109
neuromuscular synaptic transmission GO:0007274 67 0.108
Fly
cell junction organization GO:0034330 57 0.106
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.106
Rat
regulation of embryonic development GO:0045995 68 0.104
synapse assembly GO:0007416 143 0.103
Fly
nephrocyte differentiation GO:0061319 12 0.102
determination of adult lifespan GO:0008340 137 0.102
regulation of embryonic cell shape GO:0016476 30 0.102
humoral immune response GO:0006959 117 0.101
initiation of dorsal closure GO:0007392 12 0.096
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.095
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.094
cell adhesion GO:0007155 136 0.092
Human Mouse
positive regulation of cell motility GO:2000147 3 0.091
Human Zebrafish Mouse
dna metabolic process GO:0006259 227 0.091
Rat
endocytosis GO:0006897 310 0.091
negative regulation of cellular component organization GO:0051129 108 0.091
Fly
response to glucose GO:0009749 2 0.091
cognition GO:0050890 141 0.090
positive regulation of protein kinase activity GO:0045860 25 0.090
Fly
skeletal muscle fiber development GO:0048741 3 0.088
growth GO:0040007 359 0.087
positive regulation of defense response GO:0031349 59 0.087
cellular catabolic process GO:0044248 372 0.086
negative regulation of programmed cell death GO:0043069 72 0.085
regulation of multi organism process GO:0043900 131 0.084
positive regulation of intracellular signal transduction GO:1902533 116 0.084
neuromuscular junction development GO:0007528 149 0.081
Fly
secondary metabolic process GO:0019748 75 0.080
regulation of photoreceptor cell differentiation GO:0046532 34 0.080
renal filtration cell differentiation GO:0061318 12 0.080
response to carbon dioxide GO:0010037 4 0.080
establishment of proximal distal cell polarity GO:0022606 4 0.080
Fly
regulation of cysteine type endopeptidase activity GO:2000116 27 0.080
embryo development ending in birth or egg hatching GO:0009792 152 0.078
negative regulation of kinase activity GO:0033673 16 0.078
positive regulation of protein serine threonine kinase activity GO:0071902 15 0.078
Fly
positive regulation of response to wounding GO:1903036 15 0.077
larval visceral muscle development GO:0007523 9 0.077
positive regulation of secretion GO:0051047 22 0.077
amine metabolic process GO:0009308 12 0.077
regulation of cellular component biogenesis GO:0044087 201 0.076
Human Mouse Fly
negative regulation of peptidase activity GO:0010466 11 0.076
regulation of mitotic cell cycle GO:0007346 190 0.075
protein catabolic process GO:0030163 101 0.074
mitochondrion organization GO:0007005 65 0.074
neurological system process GO:0050877 358 0.073
Mouse Fly
regulation of anatomical structure size GO:0090066 163 0.073
Mouse Fly
morphogenesis of a polarized epithelium GO:0001738 93 0.073
Mouse Fly
neuron remodeling GO:0016322 29 0.072
chorion containing eggshell formation GO:0007304 105 0.072
lateral inhibition GO:0046331 206 0.072
developmental pigmentation GO:0048066 68 0.071
peptidyl amino acid modification GO:0018193 105 0.071
striated muscle tissue development GO:0014706 27 0.071
regulation of cellular localization GO:0060341 136 0.071
cell maturation GO:0048469 144 0.070
pericardial nephrocyte differentiation GO:0061320 9 0.070
digestive system development GO:0055123 149 0.070
Fly
regulation of rho protein signal transduction GO:0035023 20 0.070
response to oxygen containing compound GO:1901700 200 0.068
protein complex assembly GO:0006461 200 0.068
Mouse Fly
regulation of innate immune response GO:0045088 71 0.067
metarhodopsin inactivation GO:0016060 5 0.067
homeostatic process GO:0042592 199 0.067
Zebrafish Rat
immune response activating signal transduction GO:0002757 2 0.067
regulation of protein kinase activity GO:0045859 51 0.066
Fly
regulation of cell cell adhesion GO:0022407 21 0.066
negative regulation of protein metabolic process GO:0051248 85 0.066
autophagic vacuole assembly GO:0000045 2 0.065
developmental growth GO:0048589 280 0.064
regulation of small gtpase mediated signal transduction GO:0051056 93 0.064
chaeta development GO:0022416 97 0.064
mitotic nuclear division GO:0007067 213 0.064
feeding behavior GO:0007631 50 0.063
regulation of dendrite morphogenesis GO:0048814 28 0.063
Fly
muscle system process GO:0003012 21 0.063
negative regulation of cell cycle GO:0045786 116 0.062
regulation of organ morphogenesis GO:2000027 78 0.062
Mouse
negative regulation of growth GO:0045926 84 0.062
dorsal ventral pattern formation GO:0009953 133 0.062
stem cell differentiation GO:0048863 117 0.062
positive regulation of neurotransmitter transport GO:0051590 2 0.062
positive regulation of cell migration GO:0030335 2 0.062
Human Zebrafish Mouse
muscle fiber development GO:0048747 12 0.062
Fly
actin polymerization or depolymerization GO:0008154 31 0.061
Mouse Fly
proteolysis GO:0006508 192 0.061
actin filament bundle assembly GO:0051017 26 0.061
eye development GO:0001654 323 0.060
guanosine containing compound catabolic process GO:1901069 74 0.060
cellular response to carbon dioxide GO:0071244 2 0.060
dorsal appendage formation GO:0046843 47 0.060
cellular amine metabolic process GO:0044106 12 0.059
semaphorin plexin signaling pathway GO:0071526 4 0.059
Rat
positive regulation of immune response GO:0050778 63 0.059
establishment or maintenance of cell polarity GO:0007163 167 0.059
muscle cell development GO:0055001 50 0.059
Fly
positive regulation of cell projection organization GO:0031346 29 0.057
Human Mouse Fly
lamellipodium organization GO:0097581 21 0.057
negative regulation of cellular protein metabolic process GO:0032269 85 0.057
detection of light stimulus involved in visual perception GO:0050908 6 0.057
histone modification GO:0016570 106 0.056
regulation of growth GO:0040008 233 0.056
Fly
regulation of gliogenesis GO:0014013 11 0.056
positive regulation of multicellular organismal process GO:0051240 143 0.055
Worm
regulation of cell projection organization GO:0031344 92 0.054
single organismal cell cell adhesion GO:0016337 45 0.053
Human
erk1 and erk2 cascade GO:0070371 39 0.053
sensory organ morphogenesis GO:0090596 260 0.052
embryonic ectodermal digestive tract morphogenesis GO:0048613 4 0.052
Fly
filopodium assembly GO:0046847 33 0.052
Fly
mesoderm development GO:0007498 78 0.052
Fly
secretion GO:0046903 109 0.052
tissue morphogenesis GO:0048729 297 0.052
phagocytosis GO:0006909 215 0.051
positive regulation of proteolysis GO:0045862 52 0.051
dorsal closure elongation of leading edge cells GO:0007394 10 0.051
transmembrane transport GO:0055085 139 0.051
regulation of lamellipodium assembly GO:0010591 15 0.051
Human Mouse Fly
establishment of cell polarity GO:0030010 40 0.050
Fly
positive regulation of rna biosynthetic process GO:1902680 266 0.050
regulation of actin polymerization or depolymerization GO:0008064 27 0.050
Mouse Fly
chromosome organization GO:0051276 360 0.050
eye morphogenesis GO:0048592 260 0.050
open tracheal system development GO:0007424 204 0.050
larval development GO:0002164 104 0.049
Worm
hematopoietic or lymphoid organ development GO:0048534 57 0.049
regulation of apoptotic process GO:0042981 130 0.048
actin filament polymerization GO:0030041 27 0.048
Mouse Fly
oocyte microtubule cytoskeleton polarization GO:0008103 22 0.048
regulation of cell division GO:0051302 72 0.048
response to alcohol GO:0097305 95 0.046
regulation of r7 cell differentiation GO:0045676 15 0.046
regulation of developmental pigmentation GO:0048070 24 0.046
activation of mapk activity GO:0000187 9 0.046
positive regulation of apoptotic process GO:0043065 47 0.045
cellular response to chemical stimulus GO:0070887 199 0.044
Human Mouse Rat
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.044
negative regulation of cellular metabolic process GO:0031324 382 0.044
peptidyl tyrosine modification GO:0018212 24 0.044
nucleotide catabolic process GO:0009166 109 0.044
nuclear division GO:0000280 332 0.044
positive regulation of catalytic activity GO:0043085 118 0.044
Mouse Fly
endodermal cell differentiation GO:0035987 3 0.044
signal transduction by phosphorylation GO:0023014 107 0.043
positive regulation of jun kinase activity GO:0043507 4 0.043
response to growth factor GO:0070848 31 0.043
wnt signaling pathway GO:0016055 98 0.042
Mouse
positive regulation of cell cycle GO:0045787 43 0.042
cytokinesis GO:0000910 90 0.042
axon guidance GO:0007411 233 0.041
Mouse Worm Fly
purine nucleotide metabolic process GO:0006163 146 0.041
cellular response to growth factor stimulus GO:0071363 30 0.041
positive regulation of neuron differentiation GO:0045666 26 0.041
cell migration involved in gastrulation GO:0042074 9 0.041
Fly
posttranscriptional regulation of gene expression GO:0010608 145 0.041
organ formation GO:0048645 39 0.041
single organism catabolic process GO:0044712 228 0.041
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 25 0.041
negative regulation of intracellular signal transduction GO:1902532 57 0.041
adult behavior GO:0030534 137 0.040
cardioblast differentiation GO:0010002 20 0.040
epidermal growth factor receptor signaling pathway GO:0007173 58 0.040
response to fibroblast growth factor GO:0071774 10 0.040
regulation of synaptic growth at neuromuscular junction GO:0008582 89 0.040
Fly
embryonic digestive tract development GO:0048566 5 0.040
Fly
regulation of nervous system development GO:0051960 248 0.040
transforming growth factor beta receptor signaling pathway GO:0007179 16 0.040
embryonic digestive tract morphogenesis GO:0048557 4 0.040
Fly
camp biosynthetic process GO:0006171 17 0.040
eye photoreceptor cell fate commitment GO:0042706 37 0.040
heart morphogenesis GO:0003007 32 0.040
convergent extension involved in gastrulation GO:0060027 2 0.039
cell type specific apoptotic process GO:0097285 38 0.039
regulation of cell projection assembly GO:0060491 30 0.039
Human Mouse Fly
death GO:0016265 284 0.039
organelle fission GO:0048285 340 0.038
cardiocyte differentiation GO:0035051 29 0.038
regulation of purine nucleotide metabolic process GO:1900542 62 0.038
small gtpase mediated signal transduction GO:0007264 88 0.038
defense response to gram negative bacterium GO:0050829 94 0.037
positive regulation of nervous system development GO:0051962 69 0.037
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.037
dorsal closure GO:0007391 79 0.037
hemocyte development GO:0007516 7 0.037
Fly
regulation of ras protein signal transduction GO:0046578 93 0.037
activation of innate immune response GO:0002218 4 0.037
nucleoside phosphate catabolic process GO:1901292 110 0.037
regulation of cellular response to stress GO:0080135 89 0.037
membrane organization GO:0061024 112 0.036
Mouse Worm
negative regulation of developmental process GO:0051093 201 0.036
pigment cell differentiation GO:0050931 3 0.036
ventral furrow formation GO:0007370 17 0.036
regulation of cell adhesion GO:0030155 27 0.035
Human
negative regulation of phosphate metabolic process GO:0045936 45 0.035
border follicle cell migration GO:0007298 113 0.035
Fly
mating GO:0007618 120 0.035
signal transduction in response to dna damage GO:0042770 3 0.035
mesoderm formation GO:0001707 21 0.034
Fly
protein autophosphorylation GO:0046777 15 0.034
single organism biosynthetic process GO:0044711 206 0.034
negative regulation of phosphorus metabolic process GO:0010563 45 0.034
negative regulation of protein phosphorylation GO:0001933 17 0.034
regulation of antimicrobial peptide production GO:0002784 44 0.033
positive regulation of kinase activity GO:0033674 25 0.033
Mouse Fly
negative regulation of neurogenesis GO:0050768 53 0.033
regulation of nuclear division GO:0051783 58 0.033
nucleotide metabolic process GO:0009117 161 0.033
neuron maturation GO:0042551 31 0.033
single organism cellular localization GO:1902580 180 0.033
positive regulation of i kappab kinase nf kappab signaling GO:0043123 1 0.032
positive regulation of transferase activity GO:0051347 26 0.032
Mouse Fly
negative regulation of rna metabolic process GO:0051253 251 0.032
organ or tissue specific immune response GO:0002251 10 0.032
activation of protein kinase activity GO:0032147 12 0.032
cell cell junction assembly GO:0007043 38 0.032
regulation of cell growth GO:0001558 43 0.032
cardioblast cell fate commitment GO:0042684 14 0.031
dopamine receptor signaling pathway GO:0007212 4 0.031
positive regulation of erk1 and erk2 cascade GO:0070374 36 0.031
extrinsic apoptotic signaling pathway GO:0097191 1 0.031
carbohydrate derivative biosynthetic process GO:1901137 85 0.031
negative regulation of cell cycle process GO:0010948 109 0.031
multi organism reproductive behavior GO:0044705 121 0.031
cellular ketone metabolic process GO:0042180 24 0.031
embryonic ectodermal digestive tract development GO:0048611 4 0.031
Fly
regulation of nucleotide metabolic process GO:0006140 62 0.031
erbb signaling pathway GO:0038127 58 0.030
imaginal disc derived wing hair site selection GO:0035320 4 0.030
Fly
response to other organism GO:0051707 293 0.030
regulation of apoptotic signaling pathway GO:2001233 10 0.030
purine nucleoside catabolic process GO:0006152 112 0.030
single organism carbohydrate metabolic process GO:0044723 72 0.030
locomotory behavior GO:0007626 176 0.030
establishment of glial blood brain barrier GO:0060857 14 0.030
carbohydrate metabolic process GO:0005975 82 0.030
cellular component maintenance GO:0043954 23 0.030
imaginal disc derived wing hair outgrowth GO:0035318 1 0.030
Fly
positive regulation of r7 cell differentiation GO:0045678 7 0.030
response to ethanol GO:0045471 59 0.029
positive regulation of purine nucleotide metabolic process GO:1900544 55 0.029
response to oxidative stress GO:0006979 86 0.029
positive regulation of protein transport GO:0051222 37 0.029
r7 cell fate commitment GO:0007465 12 0.029
dephosphorylation GO:0016311 51 0.029
nucleoside metabolic process GO:0009116 127 0.029
multicellular organismal reproductive behavior GO:0033057 110 0.029
positive regulation of neuron apoptotic process GO:0043525 1 0.029
oocyte maturation GO:0001556 3 0.028
protein processing GO:0016485 68 0.028
oocyte development GO:0048599 124 0.028
ribose phosphate metabolic process GO:0019693 145 0.028
adherens junction maintenance GO:0034334 9 0.028
apoptotic process GO:0006915 159 0.028
regulation of canonical wnt signaling pathway GO:0060828 15 0.028
positive regulation of cellular response to insulin stimulus GO:1900078 4 0.028
oocyte differentiation GO:0009994 145 0.028
reactive oxygen species metabolic process GO:0072593 22 0.027
regulation of response to biotic stimulus GO:0002831 63 0.027
response to inorganic substance GO:0010035 44 0.027
positive regulation of actin filament polymerization GO:0030838 11 0.027
Mouse
development of primary sexual characteristics GO:0045137 50 0.027
Worm
positive regulation of programmed cell death GO:0043068 62 0.027
response to decreased oxygen levels GO:0036293 58 0.027
autophagy GO:0006914 108 0.027
chromosome segregation GO:0007059 157 0.027
regulation of cell cycle process GO:0010564 181 0.026
epithelial cell development GO:0002064 274 0.026
cellular macromolecule localization GO:0070727 220 0.026
positive regulation of cellular component biogenesis GO:0044089 80 0.026
Human Mouse Fly
negative regulation of gene expression GO:0010629 387 0.026
phagocytosis engulfment GO:0006911 11 0.026
Mouse Worm
macromolecular complex assembly GO:0065003 256 0.026
Mouse Fly
cellular response to extracellular stimulus GO:0031668 64 0.025

Rac2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
cardiovascular system disease DOID:1287 0 0.029
disease of anatomical entity DOID:7 0 0.029