Drosophila melanogaster

87 known processes

akirin (Dmel_CG8580)

CG8580 gene product from transcript CG8580-RD

(Aliases: Dmel\CG8580,CG8580,anon-WO0118547.397,EP(3)0906,Akirin,bhr,DmAkirin)

akirin biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
muscle structure development GO:0061061 224 0.644
dendrite development GO:0016358 204 0.279
multi organism reproductive behavior GO:0044705 121 0.273
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.251
imaginal disc derived appendage development GO:0048737 399 0.226
embryonic morphogenesis GO:0048598 206 0.169
dendrite morphogenesis GO:0048813 199 0.158
negative regulation of developmental process GO:0051093 201 0.156
negative regulation of gene expression GO:0010629 387 0.151
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.150
negative regulation of cellular biosynthetic process GO:0031327 277 0.137
defense response GO:0006952 300 0.133
muscle cell differentiation GO:0042692 103 0.131
striated muscle cell development GO:0055002 50 0.127
single organism behavior GO:0044708 391 0.126
organophosphate metabolic process GO:0019637 195 0.119
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.115
positive regulation of macromolecule metabolic process GO:0010604 405 0.107
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.106
aromatic compound catabolic process GO:0019439 166 0.104
muscle organ development GO:0007517 127 0.102
mrna metabolic process GO:0016071 124 0.098
epithelial cell development GO:0002064 274 0.096
establishment of localization in cell GO:0051649 402 0.092
cell death GO:0008219 279 0.091
central nervous system development GO:0007417 201 0.084
positive regulation of gene expression GO:0010628 290 0.080
morphogenesis of an epithelium GO:0002009 276 0.078
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.078
chromatin assembly or disassembly GO:0006333 52 0.073
positive regulation of nucleic acid templated transcription GO:1903508 266 0.071
striated muscle cell differentiation GO:0051146 90 0.071
positive regulation of biosynthetic process GO:0009891 316 0.070
multi multicellular organism process GO:0044706 123 0.069
chromosome organization GO:0051276 360 0.067
response to starvation GO:0042594 97 0.065
positive regulation of response to stimulus GO:0048584 323 0.064
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.064
homeostatic process GO:0042592 199 0.063
regulation of transport GO:0051049 181 0.063
intracellular transport GO:0046907 228 0.061
establishment or maintenance of cell polarity GO:0007163 167 0.060
negative regulation of transcription dna templated GO:0045892 237 0.059
cellular protein modification process GO:0006464 438 0.055
negative regulation of rna metabolic process GO:0051253 251 0.055
chromatin assembly GO:0031497 48 0.055
dna metabolic process GO:0006259 227 0.052
negative regulation of protein metabolic process GO:0051248 85 0.051
actin filament based process GO:0030029 220 0.051
multicellular organismal reproductive behavior GO:0033057 110 0.050
regulation of localization GO:0032879 275 0.049
convergent extension GO:0060026 2 0.049
protein modification process GO:0036211 438 0.049
positive regulation of transcription dna templated GO:0045893 266 0.048
actin cytoskeleton organization GO:0030036 206 0.047
regulation of translation GO:0006417 56 0.046
macromolecule catabolic process GO:0009057 161 0.046
positive regulation of rna biosynthetic process GO:1902680 266 0.045
negative regulation of cell differentiation GO:0045596 143 0.044
heterocycle catabolic process GO:0046700 166 0.042
regionalization GO:0003002 416 0.042
cell aging GO:0007569 2 0.042
defense response to other organism GO:0098542 225 0.041
mrna processing GO:0006397 104 0.041
intracellular signal transduction GO:0035556 300 0.041
organic cyclic compound catabolic process GO:1901361 168 0.040
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.040
protein complex assembly GO:0006461 200 0.039
organic substance catabolic process GO:1901575 308 0.039
response to external biotic stimulus GO:0043207 293 0.039
positive regulation of cell differentiation GO:0045597 64 0.037
myotube cell development GO:0014904 3 0.034
response to extracellular stimulus GO:0009991 116 0.033
epithelial cell differentiation GO:0030855 322 0.033
brain development GO:0007420 120 0.033
positive regulation of phosphate metabolic process GO:0045937 139 0.032
protein localization GO:0008104 284 0.032
chromosome segregation GO:0007059 157 0.032
response to biotic stimulus GO:0009607 294 0.031
humoral immune response GO:0006959 117 0.031
single organism intracellular transport GO:1902582 207 0.030
cellular homeostasis GO:0019725 80 0.030
organic substance transport GO:0071702 257 0.029
endocytosis GO:0006897 310 0.029
regulation of phosphorylation GO:0042325 147 0.029
negative regulation of translation GO:0017148 28 0.028
reproductive behavior GO:0019098 122 0.028
positive regulation of cellular biosynthetic process GO:0031328 316 0.028
phosphorylation GO:0016310 294 0.027
regulation of protein metabolic process GO:0051246 256 0.026
cellular nitrogen compound catabolic process GO:0044270 165 0.026
nucleoside catabolic process GO:0009164 112 0.026
chromatin organization GO:0006325 207 0.026
regulation of nervous system development GO:0051960 248 0.026
skeletal muscle organ development GO:0060538 48 0.025
mrna transport GO:0051028 15 0.025
regulation of cell cycle GO:0051726 291 0.025
purine ribonucleotide catabolic process GO:0009154 109 0.025
nucleoside phosphate catabolic process GO:1901292 110 0.024
regulation of neurogenesis GO:0050767 158 0.024
chemotaxis GO:0006935 249 0.024
neuron projection guidance GO:0097485 241 0.023
positive regulation of intracellular signal transduction GO:1902533 116 0.023
positive regulation of mapk cascade GO:0043410 63 0.023
multi organism behavior GO:0051705 175 0.022
positive regulation of rna metabolic process GO:0051254 271 0.022
hindgut development GO:0061525 58 0.022
circulatory system development GO:0072359 82 0.022
head development GO:0060322 135 0.022
proteolysis GO:0006508 192 0.021
positive regulation of developmental process GO:0051094 143 0.021
cellular catabolic process GO:0044248 372 0.021
negative regulation of rna biosynthetic process GO:1902679 240 0.021
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.021
antimicrobial humoral response GO:0019730 99 0.021
nucleotide catabolic process GO:0009166 109 0.020
protein modification by small protein conjugation GO:0032446 79 0.020
organophosphate catabolic process GO:0046434 112 0.020
salivary gland development GO:0007431 162 0.020
cellular macromolecular complex assembly GO:0034622 153 0.020
protein catabolic process GO:0030163 101 0.019
ribonucleoside metabolic process GO:0009119 127 0.019
purine nucleotide catabolic process GO:0006195 109 0.019
vesicle mediated transport GO:0016192 381 0.019
cytoplasmic transport GO:0016482 130 0.018
response to nutrient levels GO:0031667 114 0.018
reproductive system development GO:0061458 74 0.018
positive regulation of cellular protein metabolic process GO:0032270 118 0.018
small molecule metabolic process GO:0044281 305 0.018
protein dna complex assembly GO:0065004 63 0.018
cellular macromolecule catabolic process GO:0044265 136 0.018
imaginal disc derived appendage morphogenesis GO:0035114 395 0.018
ribonucleotide catabolic process GO:0009261 109 0.018
nuclear transport GO:0051169 72 0.018
forebrain development GO:0030900 2 0.017
positive regulation of phosphorylation GO:0042327 87 0.017
oocyte microtubule cytoskeleton organization GO:0016325 35 0.017
regulation of multicellular organismal development GO:2000026 414 0.017
nucleobase containing small molecule metabolic process GO:0055086 174 0.017
spindle organization GO:0007051 253 0.017
body morphogenesis GO:0010171 2 0.017
actomyosin structure organization GO:0031032 56 0.017
columnar cuboidal epithelial cell development GO:0002066 249 0.016
regulation of mapk cascade GO:0043408 92 0.016
translation GO:0006412 69 0.016
positive regulation of neuron differentiation GO:0045666 26 0.016
production of molecular mediator of immune response GO:0002440 46 0.016
negative regulation of nucleic acid templated transcription GO:1903507 240 0.016
organelle assembly GO:0070925 198 0.016
positive regulation of nervous system development GO:0051962 69 0.016
taxis GO:0042330 304 0.016
protein maturation GO:0051604 71 0.016
microtubule organizing center organization GO:0031023 168 0.015
sex differentiation GO:0007548 81 0.015
ribonucleoside triphosphate metabolic process GO:0009199 119 0.015
axonogenesis GO:0007409 290 0.015
rna processing GO:0006396 147 0.015
dorsal ventral pattern formation GO:0009953 133 0.014
response to abiotic stimulus GO:0009628 341 0.014
negative regulation of cellular protein metabolic process GO:0032269 85 0.014
striated muscle myosin thick filament assembly GO:0071688 3 0.014
nucleotide metabolic process GO:0009117 161 0.014
regulation of multi organism process GO:0043900 131 0.014
protein phosphorylation GO:0006468 169 0.014
appendage development GO:0048736 401 0.014
mitochondrion organization GO:0007005 65 0.014
development of primary sexual characteristics GO:0045137 50 0.014
positive regulation of molecular function GO:0044093 136 0.014
regulation of cell differentiation GO:0045595 302 0.014
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.014
oocyte differentiation GO:0009994 145 0.014
negative regulation of cellular metabolic process GO:0031324 382 0.014
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.014
larval development GO:0002164 104 0.014
ribose phosphate metabolic process GO:0019693 145 0.013
ribonucleoside triphosphate catabolic process GO:0009203 108 0.013
regulation of cytoskeleton organization GO:0051493 89 0.013
purine ribonucleotide metabolic process GO:0009150 145 0.013
phagocytosis GO:0006909 215 0.013
nucleocytoplasmic transport GO:0006913 72 0.013
peptidyl amino acid modification GO:0018193 105 0.013
single organismal cell cell adhesion GO:0016337 45 0.013
transcription from rna polymerase ii promoter GO:0006366 368 0.012
mapk cascade GO:0000165 107 0.012
purine nucleotide metabolic process GO:0006163 146 0.012
macromolecular complex assembly GO:0065003 256 0.012
embryo development ending in birth or egg hatching GO:0009792 152 0.012
axon regeneration GO:0031103 8 0.012
pronuclear migration GO:0035046 4 0.012
neurological system process GO:0050877 358 0.012
mrna splicing via spliceosome GO:0000398 73 0.012
regulation of neuron differentiation GO:0045664 103 0.012
alternative mrna splicing via spliceosome GO:0000380 60 0.012
catabolic process GO:0009056 409 0.012
cation homeostasis GO:0055080 51 0.012
regulation of cellular amine metabolic process GO:0033238 3 0.012
digestive tract development GO:0048565 149 0.012
male mating behavior GO:0060179 70 0.012
carbohydrate derivative catabolic process GO:1901136 118 0.012
nucleoside phosphate metabolic process GO:0006753 162 0.012
protein dna complex subunit organization GO:0071824 86 0.012
centriole replication GO:0007099 24 0.012
appendage morphogenesis GO:0035107 397 0.011
activation of cysteine type endopeptidase activity involved in apoptotic process GO:0006919 16 0.011
regulation of cytoplasmic transport GO:1903649 47 0.011
regulation of response to external stimulus GO:0032101 115 0.011
mrna 3 end processing GO:0031124 28 0.011
modification dependent protein catabolic process GO:0019941 78 0.011
locomotory behavior GO:0007626 176 0.011
single organism catabolic process GO:0044712 228 0.011
segmentation GO:0035282 207 0.011
nucleoside triphosphate metabolic process GO:0009141 120 0.011
reproductive structure development GO:0048608 74 0.011
negative regulation of nervous system development GO:0051961 92 0.011
dna conformation change GO:0071103 105 0.011
dna damage checkpoint GO:0000077 78 0.011
mrna catabolic process GO:0006402 33 0.011
anatomical structure homeostasis GO:0060249 97 0.011
cell cell signaling involved in cell fate commitment GO:0045168 210 0.011
lateral inhibition GO:0046331 206 0.011
axon guidance GO:0007411 233 0.011
cellular response to oxygen levels GO:0071453 30 0.011
carbohydrate derivative metabolic process GO:1901135 217 0.010
axon development GO:0061564 297 0.010
mitotic nuclear division GO:0007067 213 0.010
cellular cation homeostasis GO:0030003 38 0.010
stem cell differentiation GO:0048863 117 0.010
positive regulation of protein metabolic process GO:0051247 128 0.010
tissue morphogenesis GO:0048729 297 0.010
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.010
apoptotic process GO:0006915 159 0.010
mating GO:0007618 120 0.010
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.010

akirin disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.020
nervous system disease DOID:863 0 0.020
muscular disease DOID:0080000 0 0.016
musculoskeletal system disease DOID:17 0 0.016
myopathy DOID:423 0 0.015
muscle tissue disease DOID:66 0 0.015
cancer DOID:162 0 0.010
disease of cellular proliferation DOID:14566 0 0.010
organ system cancer DOID:0050686 0 0.010