Drosophila melanogaster

108 known processes

trpml (Dmel_CG8743)

transient receptor potential mucolipin

(Aliases: CG8743,Dmel\CG8743,CT25240)

trpml biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
macroautophagy GO:0016236 42 0.858
synaptic transmission GO:0007268 288 0.791
larval midgut histolysis GO:0035069 22 0.716
autophagy GO:0006914 108 0.650
regulation of catabolic process GO:0009894 170 0.454
programmed cell death GO:0012501 257 0.355
protein modification process GO:0036211 438 0.352
cellular response to extracellular stimulus GO:0031668 64 0.349
locomotory behavior GO:0007626 176 0.312
Mouse
cellular response to starvation GO:0009267 61 0.297
cell migration GO:0016477 238 0.291
establishment of localization in cell GO:0051649 402 0.285
cellular catabolic process GO:0044248 372 0.273
regulation of transport GO:0051049 181 0.267
death GO:0016265 284 0.266
ion transmembrane transport GO:0034220 122 0.235
catabolic process GO:0009056 409 0.235
response to hydrogen peroxide GO:0042542 11 0.231
regulation of autophagy GO:0010506 62 0.229
regulation of anatomical structure morphogenesis GO:0022603 242 0.220
response to extracellular stimulus GO:0009991 116 0.212
exocrine system development GO:0035272 162 0.206
single organism cellular localization GO:1902580 180 0.200
autophagic vacuole fusion GO:0000046 15 0.196
synaptic growth at neuromuscular junction GO:0051124 119 0.195
cation transport GO:0006812 110 0.191
cell death GO:0008219 279 0.191
extracellular matrix organization GO:0030198 32 0.189
mitochondrion organization GO:0007005 65 0.189
positive regulation of signaling GO:0023056 243 0.179
membrane organization GO:0061024 112 0.175
organelle fusion GO:0048284 46 0.173
positive regulation of cell communication GO:0010647 250 0.172
adult behavior GO:0030534 137 0.171
enzyme linked receptor protein signaling pathway GO:0007167 179 0.167
imaginal disc derived appendage morphogenesis GO:0035114 395 0.159
regulation of cell differentiation GO:0045595 302 0.152
neuromuscular junction development GO:0007528 149 0.152
salivary gland morphogenesis GO:0007435 145 0.149
growth GO:0040007 359 0.148
cellular response to nutrient levels GO:0031669 62 0.146
cellular protein modification process GO:0006464 438 0.141
regulation of localization GO:0032879 275 0.141
response to oxidative stress GO:0006979 86 0.141
larval midgut cell programmed cell death GO:0035096 19 0.140
regulation of multicellular organismal development GO:2000026 414 0.138
purine nucleoside triphosphate metabolic process GO:0009144 119 0.136
salivary gland development GO:0007431 162 0.135
cell motility GO:0048870 251 0.135
regulation of synapse structure and activity GO:0050803 128 0.133
post embryonic appendage morphogenesis GO:0035120 385 0.131
macromolecular complex assembly GO:0065003 256 0.131
autophagic vacuole assembly GO:0000045 2 0.124
appendage development GO:0048736 401 0.120
photoreceptor cell differentiation GO:0046530 170 0.117
regulation of cellular protein metabolic process GO:0032268 243 0.116
regulation of cell morphogenesis GO:0022604 163 0.116
transmembrane transport GO:0055085 139 0.116
positive regulation of cell death GO:0010942 69 0.112
secretion GO:0046903 109 0.112
regulation of cell death GO:0010941 173 0.112
sensory organ morphogenesis GO:0090596 260 0.110
organelle membrane fusion GO:0090174 16 0.109
regulation of protein metabolic process GO:0051246 256 0.107
imaginal disc derived appendage development GO:0048737 399 0.107
neuromuscular synaptic transmission GO:0007274 67 0.103
regulation of cellular component biogenesis GO:0044087 201 0.102
cognition GO:0050890 141 0.101
oocyte development GO:0048599 124 0.099
chorion containing eggshell formation GO:0007304 105 0.098
determination of adult lifespan GO:0008340 137 0.097
organic substance transport GO:0071702 257 0.096
nucleobase containing small molecule metabolic process GO:0055086 174 0.096
adult locomotory behavior GO:0008344 76 0.095
organonitrogen compound metabolic process GO:1901564 318 0.095
positive regulation of cellular protein metabolic process GO:0032270 118 0.095
single organism catabolic process GO:0044712 228 0.095
localization of cell GO:0051674 257 0.095
endocytosis GO:0006897 310 0.091
single organism behavior GO:0044708 391 0.090
glycosyl compound metabolic process GO:1901657 127 0.090
histolysis GO:0007559 102 0.089
regulation of cellular localization GO:0060341 136 0.088
positive regulation of molecular function GO:0044093 136 0.087
regulation of synapse organization GO:0050807 110 0.087
regulation of cellular amine metabolic process GO:0033238 3 0.087
erbb signaling pathway GO:0038127 58 0.086
regulation of synaptic growth at neuromuscular junction GO:0008582 89 0.086
cell cycle phase transition GO:0044770 140 0.086
body morphogenesis GO:0010171 2 0.086
positive regulation of protein metabolic process GO:0051247 128 0.086
gland development GO:0048732 191 0.084
lipid metabolic process GO:0006629 121 0.083
regulation of protein modification process GO:0031399 112 0.083
phosphorylation GO:0016310 294 0.083
anatomical structure homeostasis GO:0060249 97 0.083
regulation of organelle organization GO:0033043 196 0.082
regulation of mitotic cell cycle GO:0007346 190 0.082
tissue death GO:0016271 102 0.082
regionalization GO:0003002 416 0.078
small molecule metabolic process GO:0044281 305 0.077
segmentation GO:0035282 207 0.076
single organism membrane fusion GO:0044801 42 0.076
protein catabolic process GO:0030163 101 0.074
wing disc morphogenesis GO:0007472 344 0.073
cellular response to external stimulus GO:0071496 66 0.072
head development GO:0060322 135 0.072
cellular amino acid metabolic process GO:0006520 61 0.072
single organism membrane organization GO:0044802 93 0.072
proteolysis GO:0006508 192 0.071
positive regulation of macromolecule metabolic process GO:0010604 405 0.071
synapse assembly GO:0007416 143 0.071
purine nucleotide catabolic process GO:0006195 109 0.069
ion transport GO:0006811 145 0.068
positive regulation of signal transduction GO:0009967 223 0.068
epithelial cell differentiation GO:0030855 322 0.067
Mouse
nucleobase containing compound catabolic process GO:0034655 165 0.067
apoptotic process GO:0006915 159 0.067
regulation of cell cycle phase transition GO:1901987 130 0.067
positive regulation of intracellular signal transduction GO:1902533 116 0.066
regulation of phosphorylation GO:0042325 147 0.065
cellular protein localization GO:0034613 160 0.065
mitochondrial fission GO:0000266 8 0.064
single organism intracellular transport GO:1902582 207 0.064
nucleotide catabolic process GO:0009166 109 0.064
mapk cascade GO:0000165 107 0.063
protein phosphorylation GO:0006468 169 0.062
regulation of cellular catabolic process GO:0031329 157 0.061
positive regulation of cell motility GO:2000147 3 0.061
regulation of synapse assembly GO:0051963 94 0.061
signal release GO:0023061 49 0.061
defense response GO:0006952 300 0.060
positive regulation of cell migration GO:0030335 2 0.060
oocyte differentiation GO:0009994 145 0.060
neurotransmitter transport GO:0006836 37 0.059
carboxylic acid metabolic process GO:0019752 92 0.059
regulation of molecular function GO:0065009 217 0.058
positive regulation of response to stimulus GO:0048584 323 0.058
mitochondrial fusion GO:0008053 7 0.058
axonogenesis GO:0007409 290 0.057
tripartite regional subdivision GO:0007351 103 0.056
aging GO:0007568 143 0.056
purine nucleoside catabolic process GO:0006152 112 0.055
negative regulation of gene expression GO:0010629 387 0.055
response to nutrient levels GO:0031667 114 0.055
positive regulation of catabolic process GO:0009896 105 0.054
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.054
metal ion transport GO:0030001 74 0.054
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.054
compound eye development GO:0048749 307 0.054
ribonucleotide metabolic process GO:0009259 145 0.054
vesicle mediated transport GO:0016192 381 0.053
columnar cuboidal epithelial cell development GO:0002066 249 0.053
ribonucleoside catabolic process GO:0042454 112 0.052
regulation of nurse cell apoptotic process GO:0045477 9 0.052
regulation of cell development GO:0060284 215 0.051
positive regulation of phosphorylation GO:0042327 87 0.051
positive regulation of programmed cell death GO:0043068 62 0.051
response to abiotic stimulus GO:0009628 341 0.050
positive regulation of multicellular organismal process GO:0051240 143 0.050
salivary gland histolysis GO:0035070 88 0.050
single organism biosynthetic process GO:0044711 206 0.050
eye morphogenesis GO:0048592 260 0.050
cytoplasmic transport GO:0016482 130 0.050
regulation of neuron projection development GO:0010975 69 0.049
negative regulation of cell communication GO:0010648 223 0.049
eggshell formation GO:0030703 105 0.049
response to mechanical stimulus GO:0009612 28 0.048
protein localization to organelle GO:0033365 82 0.048
purine ribonucleoside metabolic process GO:0046128 127 0.047
phosphatidylinositol mediated signaling GO:0048015 4 0.047
macromolecule catabolic process GO:0009057 161 0.047
regulation of multi organism process GO:0043900 131 0.046
protein complex assembly GO:0006461 200 0.046
negative regulation of cellular component organization GO:0051129 108 0.046
regulation of mitotic cell cycle phase transition GO:1901990 130 0.046
secretion by cell GO:0032940 101 0.046
regulation of phosphorus metabolic process GO:0051174 210 0.046
embryonic pattern specification GO:0009880 174 0.045
regulation of nervous system development GO:0051960 248 0.045
ribonucleoside triphosphate metabolic process GO:0009199 119 0.045
organophosphate metabolic process GO:0019637 195 0.045
eye photoreceptor cell differentiation GO:0001754 145 0.045
vesicle localization GO:0051648 55 0.045
peptidyl threonine phosphorylation GO:0018107 2 0.044
protein complex biogenesis GO:0070271 201 0.044
aromatic compound catabolic process GO:0019439 166 0.044
regulation of ras protein signal transduction GO:0046578 93 0.044
synapse organization GO:0050808 196 0.043
protein maturation GO:0051604 71 0.043
regulation of synaptic transmission GO:0050804 69 0.043
regulation of neuron death GO:1901214 26 0.043
purine nucleotide metabolic process GO:0006163 146 0.043
nucleoside metabolic process GO:0009116 127 0.043
central nervous system development GO:0007417 201 0.043
oocyte anterior posterior axis specification GO:0007314 72 0.043
protein modification by small protein conjugation or removal GO:0070647 106 0.042
translation GO:0006412 69 0.042
regulation of bmp signaling pathway GO:0030510 23 0.042
regulation of mitochondrial fusion GO:0010635 5 0.042
appendage morphogenesis GO:0035107 397 0.042
carbohydrate derivative catabolic process GO:1901136 118 0.042
synaptic vesicle transport GO:0048489 50 0.042
protein ubiquitination GO:0016567 70 0.041
positive regulation of transport GO:0051050 92 0.041
positive regulation of cellular component organization GO:0051130 156 0.041
purine ribonucleotide catabolic process GO:0009154 109 0.041
cellular amine metabolic process GO:0044106 12 0.040
regulation of endocytosis GO:0030100 37 0.040
regulation of vesicle mediated transport GO:0060627 59 0.040
ribose phosphate metabolic process GO:0019693 145 0.040
positive regulation of protein modification process GO:0031401 58 0.040
microtubule organizing center organization GO:0031023 168 0.040
cell maturation GO:0048469 144 0.039
purine nucleoside metabolic process GO:0042278 127 0.039
detection of chemical stimulus GO:0009593 93 0.039
positive regulation of proteolysis GO:0045862 52 0.039
positive regulation of cellular component biogenesis GO:0044089 80 0.039
digestive system development GO:0055123 149 0.039
calcium ion transport GO:0006816 24 0.039
epithelial cell development GO:0002064 274 0.039
positive regulation of synaptic growth at neuromuscular junction GO:0045887 26 0.039
response to organic substance GO:0010033 284 0.038
regulation of proteolysis GO:0030162 87 0.038
glycosyl compound catabolic process GO:1901658 112 0.038
lateral inhibition GO:0046331 206 0.038
establishment of vesicle localization GO:0051650 51 0.038
positive regulation of developmental process GO:0051094 143 0.038
regulation of protein catabolic process GO:0042176 55 0.038
imaginal disc derived wing morphogenesis GO:0007476 337 0.037
germ cell migration GO:0008354 43 0.037
regulation of reproductive process GO:2000241 54 0.037
modification dependent macromolecule catabolic process GO:0043632 79 0.037
response to heat GO:0009408 63 0.037
cellular protein complex assembly GO:0043623 71 0.037
inorganic ion transmembrane transport GO:0098660 73 0.036
cation transmembrane transport GO:0098655 88 0.036
inorganic cation transmembrane transport GO:0098662 61 0.036
membrane fusion GO:0061025 42 0.036
sperm mitochondrion organization GO:0030382 7 0.035
hemopoiesis GO:0030097 46 0.035
positive regulation of catalytic activity GO:0043085 118 0.035
organonitrogen compound catabolic process GO:1901565 128 0.035
response to external biotic stimulus GO:0043207 293 0.035
regulation of protein phosphorylation GO:0001932 64 0.035
organic cyclic compound catabolic process GO:1901361 168 0.035
mitochondrion degradation GO:0000422 8 0.035
homeostatic process GO:0042592 199 0.035
protein transport GO:0015031 155 0.035
ribonucleotide catabolic process GO:0009261 109 0.035
phagocytosis GO:0006909 215 0.034
telencephalon development GO:0021537 2 0.034
autophagic cell death GO:0048102 83 0.034
cellular nitrogen compound catabolic process GO:0044270 165 0.034
regulation of embryonic development GO:0045995 68 0.034
developmental growth GO:0048589 280 0.034
vacuolar transport GO:0007034 13 0.034
neurological system process GO:0050877 358 0.034
Mouse
synaptic vesicle localization GO:0097479 53 0.034
eye development GO:0001654 323 0.033
regulation of protein transport GO:0051223 57 0.033
response to temperature stimulus GO:0009266 106 0.033
mitotic nuclear division GO:0007067 213 0.033
regulation of apoptotic process GO:0042981 130 0.033
heterocycle catabolic process GO:0046700 166 0.033
blastoderm segmentation GO:0007350 159 0.033
negative regulation of response to stimulus GO:0048585 258 0.033
regulation of mitochondrial fission GO:0090140 7 0.033
regulation of secretion by cell GO:1903530 39 0.033
positive regulation of mitochondrion organization GO:0010822 8 0.033
negative regulation of nervous system development GO:0051961 92 0.033
nucleoside triphosphate metabolic process GO:0009141 120 0.033
response to reactive oxygen species GO:0000302 24 0.032
intracellular signal transduction GO:0035556 300 0.032
reactive oxygen species metabolic process GO:0072593 22 0.032
neuron death GO:0070997 27 0.032
developmental programmed cell death GO:0010623 138 0.031
cellular protein catabolic process GO:0044257 83 0.031
positive regulation of protein phosphorylation GO:0001934 34 0.031
intracellular transport GO:0046907 228 0.031
tissue homeostasis GO:0001894 36 0.031
regulation of mitochondrion organization GO:0010821 12 0.031
synaptic vesicle endocytosis GO:0048488 28 0.031
establishment of protein localization to organelle GO:0072594 62 0.031
cellular macromolecule catabolic process GO:0044265 136 0.031
salivary gland cell autophagic cell death GO:0035071 83 0.031
positive regulation of apoptotic process GO:0043065 47 0.031
nitrogen compound transport GO:0071705 85 0.031
regulation of catalytic activity GO:0050790 185 0.030
larval behavior GO:0030537 42 0.030
positive regulation of phosphorus metabolic process GO:0010562 139 0.030
zinc ion homeostasis GO:0055069 6 0.030
endosomal transport GO:0016197 44 0.030
purine ribonucleoside catabolic process GO:0046130 112 0.029
intracellular protein transport GO:0006886 104 0.029
oocyte axis specification GO:0007309 108 0.029
regulation of response to stress GO:0080134 200 0.029
gland morphogenesis GO:0022612 145 0.029
regulation of programmed cell death GO:0043067 152 0.029
regulation of cell shape GO:0008360 113 0.029
ras protein signal transduction GO:0007265 88 0.028
response to inorganic substance GO:0010035 44 0.028
regulation of growth GO:0040008 233 0.028
open tracheal system development GO:0007424 204 0.028
memory GO:0007613 94 0.028
multicellular organismal homeostasis GO:0048871 41 0.028
regulation of mapk cascade GO:0043408 92 0.028
regulation of microtubule cytoskeleton organization GO:0070507 41 0.027
regulation of response to external stimulus GO:0032101 115 0.027
modification dependent protein catabolic process GO:0019941 78 0.027
cellular macromolecular complex assembly GO:0034622 153 0.027
cellular response to oxidative stress GO:0034599 28 0.027
organic substance catabolic process GO:1901575 308 0.027
multi organism reproductive behavior GO:0044705 121 0.027
regulation of cell cycle process GO:0010564 181 0.026
regulation of cell cycle GO:0051726 291 0.026
imaginal disc derived wing vein morphogenesis GO:0008586 44 0.026
compound eye photoreceptor cell differentiation GO:0001751 140 0.026
immune system development GO:0002520 57 0.026
purine nucleoside monophosphate metabolic process GO:0009126 50 0.026
centrosome organization GO:0051297 163 0.025
nucleotide metabolic process GO:0009117 161 0.025
response to organonitrogen compound GO:0010243 75 0.025
maternal determination of anterior posterior axis embryo GO:0008358 74 0.025
nucleoside phosphate catabolic process GO:1901292 110 0.025
regulation of synaptic vesicle endocytosis GO:1900242 7 0.025
response to wounding GO:0009611 94 0.025
positive regulation of organelle organization GO:0010638 65 0.025
purine containing compound metabolic process GO:0072521 155 0.025
regulation of anatomical structure size GO:0090066 163 0.024
wnt signaling pathway GO:0016055 98 0.024
regulation of neurotransmitter secretion GO:0046928 14 0.024
axis specification GO:0009798 167 0.024
cuticle development GO:0042335 86 0.024
regulation of macroautophagy GO:0016241 15 0.024
regulation of gtp catabolic process GO:0033124 44 0.024
mrna metabolic process GO:0016071 124 0.024
rho protein signal transduction GO:0007266 14 0.024
positive regulation of autophagy GO:0010508 21 0.024
developmental cell growth GO:0048588 52 0.024
organophosphate biosynthetic process GO:0090407 46 0.024
positive regulation of phosphate metabolic process GO:0045937 139 0.024
negative regulation of cell cycle phase transition GO:1901988 103 0.024
organelle assembly GO:0070925 198 0.024
cellular macromolecule localization GO:0070727 220 0.024
negative regulation of growth GO:0045926 84 0.024
ribonucleoside triphosphate catabolic process GO:0009203 108 0.024
regulation of excitatory postsynaptic membrane potential GO:0060079 3 0.024
regulation of nucleotide metabolic process GO:0006140 62 0.023
mitochondrion morphogenesis GO:0070584 8 0.023
extracellular structure organization GO:0043062 46 0.023
multi multicellular organism process GO:0044706 123 0.023
response to oxygen containing compound GO:1901700 200 0.023
eye antennal disc development GO:0035214 60 0.023
nucleoside triphosphate catabolic process GO:0009143 108 0.023
regulation of cellular amino acid metabolic process GO:0006521 0 0.023
protein localization GO:0008104 284 0.023
regulation of hydrolase activity GO:0051336 97 0.023
chemotaxis GO:0006935 249 0.023
cell proliferation GO:0008283 299 0.023
regulation of small gtpase mediated signal transduction GO:0051056 93 0.023
immune system process GO:0002376 347 0.022
learning or memory GO:0007611 141 0.022
male courtship behavior GO:0008049 63 0.022
dendrite morphogenesis GO:0048813 199 0.022
protein polymerization GO:0051258 42 0.022
negative regulation of cell death GO:0060548 81 0.022
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.022
cell projection assembly GO:0030031 94 0.022
urogenital system development GO:0001655 72 0.022
endomembrane system organization GO:0010256 119 0.022
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.022
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.022
regulation of cellular response to oxidative stress GO:1900407 4 0.021
negative regulation of signal transduction GO:0009968 206 0.021
nucleoside monophosphate metabolic process GO:0009123 52 0.021
negative regulation of synaptic growth at neuromuscular junction GO:0045886 39 0.021
positive regulation of protein catabolic process GO:0045732 34 0.021
atp metabolic process GO:0046034 49 0.021
protein modification by small protein conjugation GO:0032446 79 0.021
compound eye photoreceptor development GO:0042051 78 0.021
negative regulation of cellular protein metabolic process GO:0032269 85 0.021
signal transduction by phosphorylation GO:0023014 107 0.021
cell growth GO:0016049 108 0.021
establishment of synaptic vesicle localization GO:0097480 50 0.021
regulation of neuron differentiation GO:0045664 103 0.020
oocyte construction GO:0007308 112 0.020
epithelial tube morphogenesis GO:0060562 88 0.020
anterior posterior axis specification GO:0009948 109 0.020
atp biosynthetic process GO:0006754 2 0.020
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.020
molting cycle GO:0042303 56 0.020
lipid biosynthetic process GO:0008610 46 0.020
multicellular organismal aging GO:0010259 140 0.020
regulation of erbb signaling pathway GO:1901184 42 0.020
regulation of immune system process GO:0002682 176 0.020
positive regulation of cellular catabolic process GO:0031331 95 0.020
cellular lipid metabolic process GO:0044255 83 0.019
regulation of translation GO:0006417 56 0.019
divalent inorganic cation homeostasis GO:0072507 29 0.019
developmental maturation GO:0021700 172 0.019
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.019
organophosphate catabolic process GO:0046434 112 0.019
positive regulation of secretion GO:0051047 22 0.019
stress activated mapk cascade GO:0051403 52 0.019
regulation of phosphate metabolic process GO:0019220 210 0.019
positive regulation of cell differentiation GO:0045597 64 0.019
negative regulation of organelle organization GO:0010639 56 0.019
forebrain development GO:0030900 2 0.019
negative regulation of response to oxidative stress GO:1902883 1 0.019
protein processing GO:0016485 68 0.019
morphogenesis of an epithelium GO:0002009 276 0.019
neurotransmitter secretion GO:0007269 35 0.019
regulation of cell adhesion GO:0030155 27 0.019
mushroom body development GO:0016319 70 0.019
molting cycle chitin based cuticle GO:0007591 56 0.019
cellular response to reactive oxygen species GO:0034614 14 0.018
actin filament based process GO:0030029 220 0.018
embryonic morphogenesis GO:0048598 206 0.018
positive regulation of exocytosis GO:0045921 4 0.018
developmental pigmentation GO:0048066 68 0.018
cytokinesis GO:0000910 90 0.018
response to starvation GO:0042594 97 0.018
positive regulation of hydrolase activity GO:0051345 78 0.018
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.018
organic acid metabolic process GO:0006082 103 0.018
nuclear transport GO:0051169 72 0.018
inositol lipid mediated signaling GO:0048017 4 0.018
regulation of mitotic sister chromatid segregation GO:0033047 28 0.018
response to other organism GO:0051707 293 0.018
establishment or maintenance of cytoskeleton polarity GO:0030952 44 0.018
cellular response to chemical stimulus GO:0070887 199 0.018
purine ribonucleotide metabolic process GO:0009150 145 0.018
cellular component assembly involved in morphogenesis GO:0010927 151 0.018
regulation of membrane depolarization GO:0003254 1 0.018
positive regulation of protein transport GO:0051222 37 0.018
ubiquitin dependent protein catabolic process GO:0006511 78 0.018
tube development GO:0035295 244 0.018
synaptic vesicle recycling GO:0036465 28 0.018
positive regulation of mapk cascade GO:0043410 63 0.017
anterior posterior axis specification embryo GO:0008595 103 0.017
response to nitrogen compound GO:1901698 90 0.017
long term memory GO:0007616 62 0.017
posttranscriptional regulation of gene expression GO:0010608 145 0.017
anterior posterior pattern specification GO:0009952 136 0.017
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.017
eye photoreceptor cell development GO:0042462 81 0.017
negative regulation of protein metabolic process GO:0051248 85 0.017
positive regulation of macroautophagy GO:0016239 8 0.017
positive regulation of gene expression GO:0010628 290 0.017
embryonic axis specification GO:0000578 107 0.017
establishment of organelle localization GO:0051656 122 0.017
response to ketone GO:1901654 34 0.017
regulation of phosphatidylinositol 3 kinase activity GO:0043551 2 0.017
regulation of neuromuscular synaptic transmission GO:1900073 15 0.017
positive regulation of kinase activity GO:0033674 25 0.016
negative regulation of peptidyl tyrosine phosphorylation GO:0050732 6 0.016
protein targeting GO:0006605 64 0.016
response to endogenous stimulus GO:0009719 119 0.016
muscle structure development GO:0061061 224 0.016
intracellular mrna localization GO:0008298 66 0.016
regulation of nucleoside metabolic process GO:0009118 50 0.016
detection of stimulus GO:0051606 156 0.016
rna localization GO:0006403 115 0.016
negative regulation of multicellular organismal process GO:0051241 142 0.016
organelle fission GO:0048285 340 0.016
regulation of protein localization GO:0032880 76 0.016
instar larval development GO:0002168 55 0.016
regulation of protein secretion GO:0050708 13 0.016
generation of precursor metabolites and energy GO:0006091 42 0.016
regulation of neurogenesis GO:0050767 158 0.016
intracellular mrna localization involved in pattern specification process GO:0060810 56 0.015
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 37 0.015
negative regulation of cell cycle process GO:0010948 109 0.015
response to oxygen radical GO:0000305 3 0.015
nucleoside phosphate metabolic process GO:0006753 162 0.015
proteasomal protein catabolic process GO:0010498 59 0.015
positive regulation of protein kinase activity GO:0045860 25 0.015
early endosome to late endosome transport GO:0045022 3 0.015
muscle organ development GO:0007517 127 0.015
amine metabolic process GO:0009308 12 0.015
organelle localization GO:0051640 148 0.015
spindle organization GO:0007051 253 0.015
regulation of neurotransmitter levels GO:0001505 38 0.015
immune effector process GO:0002252 98 0.015
purine nucleoside biosynthetic process GO:0042451 3 0.015
membrane lipid metabolic process GO:0006643 22 0.015
detection of abiotic stimulus GO:0009582 66 0.015
ribonucleotide biosynthetic process GO:0009260 28 0.015
leg disc development GO:0035218 92 0.015
positive regulation of response to external stimulus GO:0032103 44 0.015
cellular ketone metabolic process GO:0042180 24 0.015

trpml disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.113
parkinson s disease DOID:14330 0 0.022
synucleinopathy DOID:0050890 0 0.022
central nervous system disease DOID:331 0 0.022
neurodegenerative disease DOID:1289 0 0.022
nervous system disease DOID:863 0 0.022
urinary system disease DOID:18 0 0.015