Drosophila melanogaster

67 known processes

Taz (Dmel_CG8766)

Tafazzin

(Aliases: Dmel\CG8766,tafazzin,dTAZ,TAZ,CG8766)

Taz biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
sperm individualization GO:0007291 48 0.947
spermatid differentiation GO:0048515 114 0.805
spermatid development GO:0007286 98 0.723
spermatogenesis GO:0007283 200 0.663
mitochondrion organization GO:0007005 65 0.524
male gamete generation GO:0048232 201 0.418
cellularization GO:0007349 90 0.382
sperm mitochondrion organization GO:0030382 7 0.296
mitochondrion morphogenesis GO:0070584 8 0.262
protein modification by small protein removal GO:0070646 28 0.251
mitochondrial fission GO:0000266 8 0.216
organelle membrane fusion GO:0090174 16 0.207
regulation of mitochondrial fission GO:0090140 7 0.203
mitochondrial fusion GO:0008053 7 0.179
ion transport GO:0006811 145 0.158
regulation of anatomical structure morphogenesis GO:0022603 242 0.154
imaginal disc derived wing morphogenesis GO:0007476 337 0.139
regulation of cell death GO:0010941 173 0.127
protein deubiquitination GO:0016579 17 0.126
wing disc morphogenesis GO:0007472 344 0.124
lipid homeostasis GO:0055088 33 0.124
male mating behavior GO:0060179 70 0.120
proteolysis GO:0006508 192 0.112
imaginal disc derived appendage morphogenesis GO:0035114 395 0.110
catabolic process GO:0009056 409 0.108
regulation of organelle organization GO:0033043 196 0.100
cellular protein catabolic process GO:0044257 83 0.097
response to other organism GO:0051707 293 0.096
tissue migration GO:0090130 155 0.093
protein localization GO:0008104 284 0.083
appendage development GO:0048736 401 0.074
autophagy GO:0006914 108 0.072
appendage morphogenesis GO:0035107 397 0.072
organonitrogen compound metabolic process GO:1901564 318 0.071
protein transport GO:0015031 155 0.071
meiotic nuclear division GO:0007126 151 0.071
establishment of localization in cell GO:0051649 402 0.070
regulation of protein catabolic process GO:0042176 55 0.065
small molecule metabolic process GO:0044281 305 0.065
single organism biosynthetic process GO:0044711 206 0.064
microtubule organizing center organization GO:0031023 168 0.063
post embryonic appendage morphogenesis GO:0035120 385 0.061
positive regulation of apoptotic signaling pathway GO:2001235 4 0.060
cellular catabolic process GO:0044248 372 0.060
regulation of microtubule based process GO:0032886 49 0.059
mitochondrion degradation GO:0000422 8 0.058
organic substance catabolic process GO:1901575 308 0.056
regulation of cytoskeleton organization GO:0051493 89 0.055
regulation of lipid storage GO:0010883 22 0.055
golgi organization GO:0007030 66 0.052
negative regulation of response to stimulus GO:0048585 258 0.052
protein catabolic process GO:0030163 101 0.052
modification dependent macromolecule catabolic process GO:0043632 79 0.052
regulation of cell morphogenesis GO:0022604 163 0.051
cellular macromolecule localization GO:0070727 220 0.051
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.050
regulation of mitochondrial fusion GO:0010635 5 0.050
negative regulation of gene expression GO:0010629 387 0.048
ubiquitin dependent protein catabolic process GO:0006511 78 0.047
positive regulation of signal transduction GO:0009967 223 0.046
cellular protein modification process GO:0006464 438 0.046
modification dependent protein catabolic process GO:0019941 78 0.046
locomotory behavior GO:0007626 176 0.045
cellular macromolecule catabolic process GO:0044265 136 0.045
single organism membrane organization GO:0044802 93 0.045
regulation of programmed cell death GO:0043067 152 0.044
positive regulation of signaling GO:0023056 243 0.043
ion transmembrane transport GO:0034220 122 0.042
protein modification process GO:0036211 438 0.042
negative regulation of cell death GO:0060548 81 0.041
negative regulation of cell communication GO:0010648 223 0.041
endocytosis GO:0006897 310 0.040
regulation of localization GO:0032879 275 0.040
positive regulation of organelle organization GO:0010638 65 0.040
regulation of apoptotic process GO:0042981 130 0.039
regulation of endocytosis GO:0030100 37 0.039
positive regulation of cellular component organization GO:0051130 156 0.039
intracellular signal transduction GO:0035556 300 0.039
sensory organ morphogenesis GO:0090596 260 0.037
transmembrane transport GO:0055085 139 0.037
intracellular transport GO:0046907 228 0.036
sensory perception GO:0007600 196 0.035
positive regulation of apoptotic process GO:0043065 47 0.035
protein modification by small protein conjugation or removal GO:0070647 106 0.035
response to external biotic stimulus GO:0043207 293 0.035
positive regulation of programmed cell death GO:0043068 62 0.035
actin filament based movement GO:0030048 26 0.034
macromolecule catabolic process GO:0009057 161 0.034
establishment of mitochondrion localization GO:0051654 7 0.033
rna localization GO:0006403 115 0.033
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 44 0.032
positive regulation of proteolysis GO:0045862 52 0.032
regulation of protein metabolic process GO:0051246 256 0.032
regulation of transport GO:0051049 181 0.031
organelle fusion GO:0048284 46 0.031
sterol homeostasis GO:0055092 4 0.031
transition metal ion transport GO:0000041 16 0.030
regulation of cell shape GO:0008360 113 0.030
cation transport GO:0006812 110 0.030
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.030
positive regulation of molecular function GO:0044093 136 0.029
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 4 0.029
positive regulation of lipid storage GO:0010884 4 0.029
oxoacid metabolic process GO:0043436 103 0.029
cell division GO:0051301 248 0.028
apoptotic process GO:0006915 159 0.028
carbohydrate derivative metabolic process GO:1901135 217 0.028
centrosome organization GO:0051297 163 0.028
developmental growth GO:0048589 280 0.028
single organism intracellular transport GO:1902582 207 0.028
organic substance transport GO:0071702 257 0.027
organelle fission GO:0048285 340 0.027
epithelial cell differentiation GO:0030855 322 0.027
adult locomotory behavior GO:0008344 76 0.027
response to biotic stimulus GO:0009607 294 0.027
regulation of intracellular signal transduction GO:1902531 236 0.026
endomembrane system organization GO:0010256 119 0.026
negative regulation of gene expression epigenetic GO:0045814 77 0.026
regulation of multicellular organismal development GO:2000026 414 0.026
cellular amine metabolic process GO:0044106 12 0.025
camera type eye development GO:0043010 4 0.025
negative regulation of cellular catabolic process GO:0031330 34 0.025
ovarian follicle cell migration GO:0007297 121 0.024
programmed cell death GO:0012501 257 0.024
establishment of protein localization GO:0045184 163 0.024
cholesterol homeostasis GO:0042632 3 0.024
membrane organization GO:0061024 112 0.024
regulation of gene expression epigenetic GO:0040029 128 0.024
cellular macromolecular complex assembly GO:0034622 153 0.024
regulation of microtubule cytoskeleton organization GO:0070507 41 0.024
cytoplasmic transport GO:0016482 130 0.023
organophosphate metabolic process GO:0019637 195 0.023
positive regulation of response to stimulus GO:0048584 323 0.023
phagocytosis GO:0006909 215 0.023
hemopoiesis GO:0030097 46 0.023
macromolecular complex disassembly GO:0032984 37 0.023
necrotic cell death GO:0070265 1 0.023
carboxylic acid metabolic process GO:0019752 92 0.023
oocyte construction GO:0007308 112 0.022
protein depolymerization GO:0051261 31 0.022
pole plasm rna localization GO:0007316 52 0.021
chromatin silencing GO:0006342 76 0.021
macromolecular complex assembly GO:0065003 256 0.021
synaptic transmission GO:0007268 288 0.020
response to bacterium GO:0009617 198 0.020
developmental maturation GO:0021700 172 0.020
cellular protein localization GO:0034613 160 0.020
regionalization GO:0003002 416 0.020
negative regulation of signal transduction GO:0009968 206 0.020
epithelium migration GO:0090132 148 0.020
positive regulation of cellular protein metabolic process GO:0032270 118 0.020
single organism cellular localization GO:1902580 180 0.020
protein targeting GO:0006605 64 0.020
immune system process GO:0002376 347 0.019
positive regulation of cytoskeleton organization GO:0051495 21 0.019
regulation of intracellular transport GO:0032386 64 0.019
regulation of cellular protein catabolic process GO:1903362 44 0.019
establishment of protein localization to organelle GO:0072594 62 0.019
cell death GO:0008219 279 0.019
protein localization to organelle GO:0033365 82 0.019
regulation of molecular function GO:0065009 217 0.018
intracellular protein transport GO:0006886 104 0.018
skin development GO:0043588 65 0.018
regulation of cellular ketone metabolic process GO:0010565 3 0.018
protein maturation GO:0051604 71 0.018
regulation of cell cycle GO:0051726 291 0.018
adult behavior GO:0030534 137 0.018
multicellular organismal iron ion homeostasis GO:0060586 2 0.018
regulation of proteolysis GO:0030162 87 0.018
epithelial cell development GO:0002064 274 0.017
neurological system process GO:0050877 358 0.017
positive regulation of mitochondrion organization GO:0010822 8 0.017
regulation of cellular localization GO:0060341 136 0.017
single organism behavior GO:0044708 391 0.017
inositol lipid mediated signaling GO:0048017 4 0.017
imaginal disc derived appendage development GO:0048737 399 0.017
learning or memory GO:0007611 141 0.017
organonitrogen compound biosynthetic process GO:1901566 117 0.017
protein import GO:0017038 55 0.017
organic hydroxy compound metabolic process GO:1901615 83 0.016
intracellular mrna localization GO:0008298 66 0.016
positive regulation of cell death GO:0010942 69 0.016
mating behavior GO:0007617 106 0.016
single organism carbohydrate metabolic process GO:0044723 72 0.016
negative regulation of signaling GO:0023057 219 0.016
oocyte differentiation GO:0009994 145 0.016
atp metabolic process GO:0046034 49 0.016
er associated ubiquitin dependent protein catabolic process GO:0030433 3 0.016
death GO:0016265 284 0.016
extrinsic apoptotic signaling pathway GO:0097191 1 0.016
cell growth GO:0016049 108 0.015
regulation of proteasomal protein catabolic process GO:0061136 39 0.015
ribose phosphate metabolic process GO:0019693 145 0.015
protein processing GO:0016485 68 0.015
cellular protein complex disassembly GO:0043624 35 0.015
zinc ion homeostasis GO:0055069 6 0.015
vesicle mediated transport GO:0016192 381 0.015
regulation of circadian sleep wake cycle sleep GO:0045187 21 0.015
anterior posterior pattern specification GO:0009952 136 0.015
negative regulation of programmed cell death GO:0043069 72 0.015
establishment of mitochondrion localization microtubule mediated GO:0034643 6 0.015
nucleocytoplasmic transport GO:0006913 72 0.015
regulation of growth GO:0040008 233 0.015
positive regulation of cellular component biogenesis GO:0044089 80 0.015
meiotic cell cycle process GO:1903046 132 0.015
eye development GO:0001654 323 0.015
protein complex assembly GO:0006461 200 0.015
cognition GO:0050890 141 0.015
embryonic pattern specification GO:0009880 174 0.014
protein polymerization GO:0051258 42 0.014
nitrogen compound transport GO:0071705 85 0.014
morphogenesis of an epithelium GO:0002009 276 0.014
eye morphogenesis GO:0048592 260 0.014
gene silencing GO:0016458 138 0.014
positive regulation of cell communication GO:0010647 250 0.014
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 37 0.014
asymmetric cell division GO:0008356 37 0.014
negative regulation of cellular response to oxidative stress GO:1900408 1 0.014
compound eye development GO:0048749 307 0.014
regulation of vesicle mediated transport GO:0060627 59 0.014
actin filament organization GO:0007015 126 0.014
regulation of cellular amine metabolic process GO:0033238 3 0.014
positive regulation of phosphorus metabolic process GO:0010562 139 0.014
immune system development GO:0002520 57 0.013
regulation of cellular protein metabolic process GO:0032268 243 0.013
regulation of cellular response to oxidative stress GO:1900407 4 0.013
negative regulation of response to oxidative stress GO:1902883 1 0.013
protein complex biogenesis GO:0070271 201 0.013
organophosphate biosynthetic process GO:0090407 46 0.013
negative regulation of biosynthetic process GO:0009890 277 0.013
cellular amide metabolic process GO:0043603 80 0.013
negative regulation of apoptotic process GO:0043066 63 0.013
regulation of cholesterol transport GO:0032374 1 0.013
sensory perception of mechanical stimulus GO:0050954 72 0.013
nucleus organization GO:0006997 45 0.013
cation transmembrane transport GO:0098655 88 0.013
regulation of response to stress GO:0080134 200 0.013
negative regulation of organelle organization GO:0010639 56 0.013
mrna processing GO:0006397 104 0.013
cytoplasm organization GO:0007028 64 0.013
cell cell signaling involved in cell fate commitment GO:0045168 210 0.013
regulation of microtubule polymerization or depolymerization GO:0031110 27 0.012
pole plasm assembly GO:0007315 61 0.012
regulation of chromosome organization GO:0033044 64 0.012
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 18 0.012
immune response GO:0006955 246 0.012
regulation of gene silencing GO:0060968 63 0.012
nucleoside monophosphate metabolic process GO:0009123 52 0.012
positive regulation of protein complex assembly GO:0031334 22 0.012
phosphatidylinositol mediated signaling GO:0048015 4 0.012
endocytic recycling GO:0032456 13 0.012
purine nucleoside monophosphate metabolic process GO:0009126 50 0.012
oocyte anterior posterior axis specification GO:0007314 72 0.012
regulation of immune system process GO:0002682 176 0.012
plasma membrane organization GO:0007009 26 0.012
iron ion transport GO:0006826 6 0.012
protein complex localization GO:0031503 4 0.012
cytoskeleton dependent cytokinesis GO:0061640 81 0.012
hair cell differentiation GO:0035315 47 0.012
compound eye morphogenesis GO:0001745 249 0.011
retina development in camera type eye GO:0060041 4 0.011
positive regulation of endopeptidase activity GO:0010950 26 0.011
forebrain development GO:0030900 2 0.011
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.011
organic acid metabolic process GO:0006082 103 0.011
branching involved in open tracheal system development GO:0060446 45 0.011
mitochondrial transport GO:0006839 8 0.011
intracellular mrna localization involved in anterior posterior axis specification GO:0060811 53 0.011
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.011
heterocycle catabolic process GO:0046700 166 0.011
inorganic ion transmembrane transport GO:0098660 73 0.011
embryo development ending in birth or egg hatching GO:0009792 152 0.011
chemical homeostasis GO:0048878 92 0.011
positive regulation of peptidase activity GO:0010952 29 0.011
organelle localization GO:0051640 148 0.011
nucleotide metabolic process GO:0009117 161 0.011
ribonucleoside monophosphate metabolic process GO:0009161 51 0.011
ribonucleoside triphosphate metabolic process GO:0009199 119 0.011
protein import into nucleus GO:0006606 51 0.011
regulation of mitotic metaphase anaphase transition GO:0030071 26 0.011
intrinsic apoptotic signaling pathway GO:0097193 16 0.011
protein localization to nucleus GO:0034504 55 0.011
tripartite regional subdivision GO:0007351 103 0.011
regulation of intracellular protein transport GO:0033157 46 0.011
single organism catabolic process GO:0044712 228 0.011
lateral inhibition GO:0046331 206 0.010
positive regulation of macromolecule metabolic process GO:0010604 405 0.010
multicellular organismal homeostasis GO:0048871 41 0.010
learning GO:0007612 75 0.010
protein complex disassembly GO:0043241 36 0.010
positive regulation of proteasomal protein catabolic process GO:1901800 20 0.010
negative regulation of protein maturation GO:1903318 31 0.010
regulation of metaphase anaphase transition of cell cycle GO:1902099 26 0.010
metal ion transport GO:0030001 74 0.010
eye photoreceptor cell differentiation GO:0001754 145 0.010
negative regulation of cellular metabolic process GO:0031324 382 0.010

Taz disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
degeneration of macula and posterior pole DOID:2007 0 0.046
retinal degeneration DOID:8466 0 0.046
sensory system disease DOID:0050155 0 0.046
nervous system disease DOID:863 0 0.046
eye disease DOID:5614 0 0.046
macular degeneration DOID:4448 0 0.046
eye and adnexa disease DOID:1492 0 0.046
disease of anatomical entity DOID:7 0 0.046
retinal disease DOID:5679 0 0.046
parkinson s disease DOID:14330 0 0.033
synucleinopathy DOID:0050890 0 0.033
neurodegenerative disease DOID:1289 0 0.033
central nervous system disease DOID:331 0 0.033
disease of metabolism DOID:0014667 0 0.017
inherited metabolic disorder DOID:655 0 0.014