Drosophila melanogaster

25 known processes

Gapdh2 (Dmel_CG8893)

Glyceraldehyde 3 phosphate dehydrogenase 2

(Aliases: GAPDH II,Gapd,GADPH,GAPDH2,Gapdh-2,Dmel\CG8893,CG8893,GAPDH,GAP,Gapdh13F,GA3PDH,Gapdh)

Gapdh2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
organic acid metabolic process GO:0006082 103 0.937
oxoacid metabolic process GO:0043436 103 0.631
single organism catabolic process GO:0044712 228 0.527
catabolic process GO:0009056 409 0.411
carboxylic acid metabolic process GO:0019752 92 0.405
small molecule metabolic process GO:0044281 305 0.381
response to transition metal nanoparticle GO:1990267 9 0.272
response to metal ion GO:0010038 23 0.231
organonitrogen compound metabolic process GO:1901564 318 0.229
multicellular organismal aging GO:0010259 140 0.194
aging GO:0007568 143 0.188
organonitrogen compound biosynthetic process GO:1901566 117 0.187
single organism carbohydrate metabolic process GO:0044723 72 0.183
cellular modified amino acid metabolic process GO:0006575 45 0.156
cellular amino acid metabolic process GO:0006520 61 0.142
organic substance catabolic process GO:1901575 308 0.139
negative regulation of cellular metabolic process GO:0031324 382 0.134
developmental growth GO:0048589 280 0.131
carbohydrate metabolic process GO:0005975 82 0.124
lateral inhibition GO:0046331 206 0.118
carbohydrate derivative biosynthetic process GO:1901137 85 0.113
response to oxygen containing compound GO:1901700 200 0.111
cellular response to chemical stimulus GO:0070887 199 0.110
single organism carbohydrate catabolic process GO:0044724 7 0.095
embryo development ending in birth or egg hatching GO:0009792 152 0.093
positive regulation of molecular function GO:0044093 136 0.089
negative regulation of gene expression GO:0010629 387 0.089
organelle assembly GO:0070925 198 0.087
immune system process GO:0002376 347 0.084
growth GO:0040007 359 0.083
macromolecular complex assembly GO:0065003 256 0.079
negative regulation of biosynthetic process GO:0009890 277 0.073
response to inorganic substance GO:0010035 44 0.072
positive regulation of macromolecule metabolic process GO:0010604 405 0.071
protein complex biogenesis GO:0070271 201 0.070
purine nucleoside metabolic process GO:0042278 127 0.066
lipid localization GO:0010876 54 0.065
organic acid biosynthetic process GO:0016053 15 0.063
response to abiotic stimulus GO:0009628 341 0.061
organic substance transport GO:0071702 257 0.058
somatic muscle development GO:0007525 66 0.056
cellular catabolic process GO:0044248 372 0.056
nucleoside metabolic process GO:0009116 127 0.054
determination of adult lifespan GO:0008340 137 0.053
maintenance of location GO:0051235 73 0.053
biological adhesion GO:0022610 138 0.050
vesicle mediated transport GO:0016192 381 0.049
negative regulation of cellular biosynthetic process GO:0031327 277 0.048
myotube differentiation GO:0014902 46 0.047
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.046
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.044
single organism biosynthetic process GO:0044711 206 0.044
positive regulation of multicellular organismal process GO:0051240 143 0.042
larval development GO:0002164 104 0.042
single organism intracellular transport GO:1902582 207 0.041
ribonucleoside biosynthetic process GO:0042455 3 0.041
regulation of growth GO:0040008 233 0.040
defense response GO:0006952 300 0.040
lipid storage GO:0019915 38 0.037
homeostatic process GO:0042592 199 0.036
immune response GO:0006955 246 0.036
protein modification process GO:0036211 438 0.035
intracellular transport GO:0046907 228 0.034
negative regulation of cell communication GO:0010648 223 0.034
carbohydrate derivative metabolic process GO:1901135 217 0.034
heterocycle catabolic process GO:0046700 166 0.033
atp biosynthetic process GO:0006754 2 0.032
regulation of cellular catabolic process GO:0031329 157 0.031
protein complex assembly GO:0006461 200 0.031
response to temperature stimulus GO:0009266 106 0.030
regulation of protein metabolic process GO:0051246 256 0.030
spindle organization GO:0007051 253 0.030
generation of precursor metabolites and energy GO:0006091 42 0.030
cellular homeostasis GO:0019725 80 0.029
posttranscriptional regulation of gene expression GO:0010608 145 0.028
carbohydrate catabolic process GO:0016052 7 0.028
body morphogenesis GO:0010171 2 0.028
cell adhesion GO:0007155 136 0.028
cellular macromolecular complex assembly GO:0034622 153 0.028
positive regulation of transcription dna templated GO:0045893 266 0.027
compound eye development GO:0048749 307 0.027
negative regulation of multicellular organismal process GO:0051241 142 0.027
negative regulation of cell differentiation GO:0045596 143 0.027
single organism behavior GO:0044708 391 0.026
regulation of cell cycle GO:0051726 291 0.026
cellular protein modification process GO:0006464 438 0.026
cellular amine metabolic process GO:0044106 12 0.026
regulation of cell differentiation GO:0045595 302 0.026
negative regulation of developmental process GO:0051093 201 0.026
ion homeostasis GO:0050801 55 0.025
nucleobase containing small molecule metabolic process GO:0055086 174 0.025
organonitrogen compound catabolic process GO:1901565 128 0.025
organophosphate metabolic process GO:0019637 195 0.025
regulation of phosphate metabolic process GO:0019220 210 0.024
purine nucleoside triphosphate metabolic process GO:0009144 119 0.024
spermatogenesis GO:0007283 200 0.024
Rat
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.024
cation homeostasis GO:0055080 51 0.024
organic cyclic compound catabolic process GO:1901361 168 0.024
response to organic substance GO:0010033 284 0.024
cellular response to endogenous stimulus GO:0071495 80 0.023
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.023
centrosome organization GO:0051297 163 0.023
negative regulation of cellular component organization GO:0051129 108 0.022
regulation of molecular function GO:0065009 217 0.022
negative regulation of rna metabolic process GO:0051253 251 0.022
nucleotide metabolic process GO:0009117 161 0.022
response to nutrient levels GO:0031667 114 0.022
purine containing compound metabolic process GO:0072521 155 0.021
response to wounding GO:0009611 94 0.021
response to heat GO:0009408 63 0.021
regulation of cellular protein metabolic process GO:0032268 243 0.021
glycosyl compound metabolic process GO:1901657 127 0.021
glycerolipid catabolic process GO:0046503 3 0.020
inorganic cation transmembrane transport GO:0098662 61 0.020
positive regulation of catalytic activity GO:0043085 118 0.020
regulation of multicellular organismal development GO:2000026 414 0.020
cellular chemical homeostasis GO:0055082 40 0.020
gland development GO:0048732 191 0.020
cellular ion homeostasis GO:0006873 39 0.019
regulation of catalytic activity GO:0050790 185 0.019
mitotic spindle organization GO:0007052 220 0.019
cation transmembrane transport GO:0098655 88 0.019
negative regulation of response to stimulus GO:0048585 258 0.019
establishment of localization in cell GO:0051649 402 0.019
positive regulation of response to stimulus GO:0048584 323 0.018
forebrain development GO:0030900 2 0.018
cellular response to organic substance GO:0071310 132 0.018
negative regulation of translation GO:0017148 28 0.018
positive regulation of cysteine type endopeptidase activity GO:2001056 24 0.018
innate immune response GO:0045087 144 0.017
carboxylic acid biosynthetic process GO:0046394 15 0.017
negative regulation of nucleic acid templated transcription GO:1903507 240 0.017
regulation of immune system process GO:0002682 176 0.017
protein localization to nucleus GO:0034504 55 0.017
cytoplasmic transport GO:0016482 130 0.017
phagocytosis GO:0006909 215 0.016
wound healing GO:0042060 75 0.016
chromosome organization GO:0051276 360 0.016
cellular macromolecule localization GO:0070727 220 0.016
pyruvate metabolic process GO:0006090 7 0.016
ribonucleoside metabolic process GO:0009119 127 0.016
regulation of cell development GO:0060284 215 0.016
negative regulation of rna biosynthetic process GO:1902679 240 0.015
cellular cation homeostasis GO:0030003 38 0.015
response to biotic stimulus GO:0009607 294 0.015
regulation of localization GO:0032879 275 0.015
nucleoside catabolic process GO:0009164 112 0.015
purine ribonucleoside metabolic process GO:0046128 127 0.015
imaginal disc derived wing morphogenesis GO:0007476 337 0.015
negative regulation of nervous system development GO:0051961 92 0.015
regulation of nervous system development GO:0051960 248 0.015
syncytium formation GO:0006949 43 0.015
regulation of catabolic process GO:0009894 170 0.015
nuclear transport GO:0051169 72 0.014
pyridine containing compound metabolic process GO:0072524 3 0.014
response to external biotic stimulus GO:0043207 293 0.014
cell proliferation GO:0008283 299 0.014
negative regulation of signal transduction GO:0009968 206 0.014
nucleocytoplasmic transport GO:0006913 72 0.014
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.014
oxidation reduction process GO:0055114 123 0.014
positive regulation of gene expression GO:0010628 290 0.014
head development GO:0060322 135 0.014
positive regulation of developmental growth GO:0048639 62 0.014
transcription from rna polymerase ii promoter GO:0006366 368 0.014
regulation of anatomical structure morphogenesis GO:0022603 242 0.014
wing disc morphogenesis GO:0007472 344 0.014
response to decreased oxygen levels GO:0036293 58 0.014
nucleoside phosphate metabolic process GO:0006753 162 0.014
negative regulation of cell development GO:0010721 62 0.014
protein transport GO:0015031 155 0.013
protein targeting GO:0006605 64 0.013
mitotic nuclear division GO:0007067 213 0.013
cellular amide metabolic process GO:0043603 80 0.013
positive regulation of cellular protein metabolic process GO:0032270 118 0.013
ion transport GO:0006811 145 0.013
aromatic compound catabolic process GO:0019439 166 0.013
positive regulation of developmental process GO:0051094 143 0.013
positive regulation of nucleic acid templated transcription GO:1903508 266 0.013
nad metabolic process GO:0019674 1 0.012
regulation of anatomical structure size GO:0090066 163 0.012
positive regulation of protein metabolic process GO:0051247 128 0.012
male gamete generation GO:0048232 201 0.012
Rat
myoblast fusion GO:0007520 43 0.012
organic hydroxy compound metabolic process GO:1901615 83 0.012
cellular response to hormone stimulus GO:0032870 44 0.012
organophosphate catabolic process GO:0046434 112 0.012
response to copper ion GO:0046688 4 0.012
negative regulation of protein metabolic process GO:0051248 85 0.012
monocarboxylic acid metabolic process GO:0032787 29 0.012
regulation of cell size GO:0008361 63 0.012
cell aging GO:0007569 2 0.012
regulation of phosphorylation GO:0042325 147 0.012
cellular carbohydrate metabolic process GO:0044262 22 0.012
regulation of cellular amine metabolic process GO:0033238 3 0.012
negative regulation of signaling GO:0023057 219 0.012
positive regulation of cellular biosynthetic process GO:0031328 316 0.012
amine metabolic process GO:0009308 12 0.012
ribonucleoside catabolic process GO:0042454 112 0.011
cellular nitrogen compound catabolic process GO:0044270 165 0.011
imaginal disc derived appendage morphogenesis GO:0035114 395 0.011
nucleobase containing compound transport GO:0015931 56 0.011
cellular response to extracellular stimulus GO:0031668 64 0.011
regulation of innate immune response GO:0045088 71 0.011
phosphorylation GO:0016310 294 0.011
protein targeting to nucleus GO:0044744 51 0.011
response to lithium ion GO:0010226 1 0.011
cellular metal ion homeostasis GO:0006875 31 0.011
regulation of organelle organization GO:0033043 196 0.011
response to calcium ion GO:0051592 1 0.011
small molecule catabolic process GO:0044282 21 0.011
striated muscle myosin thick filament assembly GO:0071688 3 0.011
regulation of apoptotic process GO:0042981 130 0.011
divalent inorganic cation homeostasis GO:0072507 29 0.011
taxis GO:0042330 304 0.011
response to hexose GO:0009746 3 0.011
response to lipid GO:0033993 38 0.011
regulation of programmed cell death GO:0043067 152 0.011
actin filament based process GO:0030029 220 0.011
regulation of lipid transport GO:0032368 3 0.011
protein maturation GO:0051604 71 0.010
cellular response to decreased oxygen levels GO:0036294 30 0.010
positive regulation of growth GO:0045927 75 0.010
retina development in camera type eye GO:0060041 4 0.010
regulation of cellular component size GO:0032535 98 0.010
cellular protein complex assembly GO:0043623 71 0.010
inorganic ion transmembrane transport GO:0098660 73 0.010
ribonucleotide metabolic process GO:0009259 145 0.010

Gapdh2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.170
acquired metabolic disease DOID:0060158 0 0.170
glucose metabolism disease DOID:4194 0 0.170
carbohydrate metabolism disease DOID:0050013 0 0.170
disease of anatomical entity DOID:7 0 0.037
inherited metabolic disorder DOID:655 0 0.023