Drosophila melanogaster

125 known processes

otk (Dmel_CG8967)

off-track

(Aliases: CG8967,Dtrk,OTK,anon-WO2004063362.81,Dmel\CG8967,Tk48D,CT25769,DTrk,dTrk,Otk,Trk48D,OFT/TRK,IGGtyk,Dtkr)

otk biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
motor neuron axon guidance GO:0008045 58 0.989
axon guidance GO:0007411 233 0.987
neuron projection guidance GO:0097485 241 0.963
axonogenesis GO:0007409 290 0.961
retinal ganglion cell axon guidance GO:0031290 12 0.923
axon development GO:0061564 297 0.840
epidermal cell differentiation GO:0009913 51 0.831
regulation of multicellular organismal development GO:2000026 414 0.823
Human Mouse
eye development GO:0001654 323 0.764
epidermis development GO:0008544 65 0.744
dendrite guidance GO:0070983 21 0.720
chemotaxis GO:0006935 249 0.680
growth GO:0040007 359 0.663
Mouse
eye morphogenesis GO:0048592 260 0.600
regulation of anatomical structure size GO:0090066 163 0.577
synaptic growth at neuromuscular junction GO:0051124 119 0.561
establishment or maintenance of cell polarity GO:0007163 167 0.529
Mouse
synapse organization GO:0050808 196 0.528
taxis GO:0042330 304 0.520
sensory organ morphogenesis GO:0090596 260 0.518
Mouse
tube morphogenesis GO:0035239 191 0.499
morphogenesis of an epithelium GO:0002009 276 0.493
Mouse
regulation of cell development GO:0060284 215 0.492
Human
compound eye development GO:0048749 307 0.489
establishment of imaginal disc derived wing hair orientation GO:0001737 24 0.487
regulation of neurogenesis GO:0050767 158 0.473
Human
anterior posterior pattern specification GO:0009952 136 0.457
biological adhesion GO:0022610 138 0.453
epithelial cell differentiation GO:0030855 322 0.436
Mouse
dendrite development GO:0016358 204 0.426
wing disc morphogenesis GO:0007472 344 0.414
imaginal disc derived wing hair organization GO:0035317 45 0.405
cell adhesion GO:0007155 136 0.392
tube development GO:0035295 244 0.385
embryonic morphogenesis GO:0048598 206 0.383
Mouse
axon midline choice point recognition GO:0016199 26 0.370
developmental growth GO:0048589 280 0.357
Mouse
regulation of anatomical structure morphogenesis GO:0022603 242 0.348
Mouse
non sensory hair organization GO:0035316 47 0.347
imaginal disc derived appendage development GO:0048737 399 0.338
post embryonic appendage morphogenesis GO:0035120 385 0.337
compound eye morphogenesis GO:0001745 249 0.322
skin development GO:0043588 65 0.320
exocrine system development GO:0035272 162 0.318
salivary gland development GO:0007431 162 0.307
appendage development GO:0048736 401 0.305
neuromuscular junction development GO:0007528 149 0.293
dorsal ventral pattern formation GO:0009953 133 0.279
imaginal disc derived wing morphogenesis GO:0007476 337 0.276
regionalization GO:0003002 416 0.261
appendage morphogenesis GO:0035107 397 0.254
olfactory bulb axon guidance GO:0071678 3 0.254
regulation of axon extension involved in axon guidance GO:0048841 4 0.254
dendrite morphogenesis GO:0048813 199 0.250
neuron projection extension GO:1990138 32 0.245
respiratory system development GO:0060541 213 0.243
Mouse
muscle structure development GO:0061061 224 0.242
cell projection assembly GO:0030031 94 0.239
regulation of localization GO:0032879 275 0.237
photoreceptor cell axon guidance GO:0072499 23 0.236
imaginal disc derived leg morphogenesis GO:0007480 80 0.230
axon choice point recognition GO:0016198 26 0.221
developmental growth involved in morphogenesis GO:0060560 65 0.221
Mouse
nephron development GO:0072006 3 0.220
axon extension GO:0048675 32 0.214
actin filament organization GO:0007015 126 0.212
regulation of developmental growth GO:0048638 174 0.211
regulation of growth GO:0040008 233 0.209
tissue morphogenesis GO:0048729 297 0.207
Mouse
transcription from rna polymerase ii promoter GO:0006366 368 0.202
establishment of localization in cell GO:0051649 402 0.201
imaginal disc derived appendage morphogenesis GO:0035114 395 0.200
torso signaling pathway GO:0008293 21 0.188
germarium derived egg chamber formation GO:0007293 101 0.186
single organismal cell cell adhesion GO:0016337 45 0.182
negative regulation of signaling GO:0023057 219 0.177
regulation of axon guidance GO:1902667 10 0.176
dorsal ventral axon guidance GO:0033563 2 0.174
organelle localization GO:0051640 148 0.173
digestive system development GO:0055123 149 0.168
negative regulation of developmental process GO:0051093 201 0.164
regulation of establishment of planar polarity GO:0090175 22 0.163
Mouse
dorsal closure GO:0007391 79 0.161
negative regulation of cell proliferation GO:0008285 69 0.159
regulation of cell morphogenesis GO:0022604 163 0.157
axon extension involved in axon guidance GO:0048846 10 0.154
regulation of phosphate metabolic process GO:0019220 210 0.150
hair cell differentiation GO:0035315 47 0.149
response to biotic stimulus GO:0009607 294 0.145
morphogenesis of a polarized epithelium GO:0001738 93 0.144
Mouse
neuron recognition GO:0008038 101 0.143
aggressive behavior GO:0002118 63 0.142
cell proliferation GO:0008283 299 0.142
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.139
regulation of neuron projection development GO:0010975 69 0.137
Human
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.136
branching morphogenesis of an epithelial tube GO:0048754 45 0.134
regulation of photoreceptor cell axon guidance GO:2000289 5 0.133
death GO:0016265 284 0.133
establishment of tissue polarity GO:0007164 87 0.128
Mouse
compound eye photoreceptor cell differentiation GO:0001751 140 0.127
regulation of phosphorus metabolic process GO:0051174 210 0.124
protein modification process GO:0036211 438 0.124
cellular protein modification process GO:0006464 438 0.123
regulation of nervous system development GO:0051960 248 0.119
Human Mouse
negative regulation of cellular metabolic process GO:0031324 382 0.119
response to external biotic stimulus GO:0043207 293 0.118
vesicle mediated transport GO:0016192 381 0.117
regulation of cell proliferation GO:0042127 163 0.116
embryo development ending in birth or egg hatching GO:0009792 152 0.116
Mouse
spinal cord development GO:0021510 1 0.113
salivary gland morphogenesis GO:0007435 145 0.113
myoblast fusion GO:0007520 43 0.113
single organism cell adhesion GO:0098602 47 0.113
regulation of molecular function GO:0065009 217 0.112
eye photoreceptor cell differentiation GO:0001754 145 0.112
photoreceptor cell differentiation GO:0046530 170 0.111
cell maturation GO:0048469 144 0.110
regulation of axonogenesis GO:0050770 32 0.110
segmentation GO:0035282 207 0.110
synaptic target recognition GO:0008039 45 0.110
axon target recognition GO:0007412 16 0.108
actin filament bundle organization GO:0061572 28 0.105
epithelial cell development GO:0002064 274 0.105
regulation of neuron differentiation GO:0045664 103 0.105
Human
response to other organism GO:0051707 293 0.104
digestive tract morphogenesis GO:0048546 127 0.104
embryonic pattern specification GO:0009880 174 0.102
kidney development GO:0001822 3 0.102
gastrulation GO:0007369 70 0.102
cell recognition GO:0008037 102 0.099
regulation of cellular component biogenesis GO:0044087 201 0.099
gland development GO:0048732 191 0.098
dorsal ventral axis specification GO:0009950 66 0.098
morphogenesis of a branching structure GO:0001763 45 0.096
tripartite regional subdivision GO:0007351 103 0.096
establishment of ommatidial planar polarity GO:0042067 49 0.096
positive regulation of cellular component organization GO:0051130 156 0.093
Human
morphogenesis of a branching epithelium GO:0061138 45 0.093
cell migration GO:0016477 238 0.090
Human
negative regulation of gene expression GO:0010629 387 0.090
embryonic development via the syncytial blastoderm GO:0001700 148 0.090
establishment or maintenance of cytoskeleton polarity GO:0030952 44 0.088
neurological system process GO:0050877 358 0.087
stem cell differentiation GO:0048863 117 0.085
regulation of cytoskeleton organization GO:0051493 89 0.085
regulation of organ morphogenesis GO:2000027 78 0.084
Mouse
digestive tract development GO:0048565 149 0.084
positive regulation of macromolecule metabolic process GO:0010604 405 0.084
cell death GO:0008219 279 0.084
positive regulation of cell migration GO:0030335 2 0.083
cell motility GO:0048870 251 0.083
Human
regulation of cellular component size GO:0032535 98 0.082
organelle fission GO:0048285 340 0.081
retina development in camera type eye GO:0060041 4 0.080
convergent extension involved in gastrulation GO:0060027 2 0.079
regulation of behavior GO:0050795 75 0.078
regulation of embryonic cell shape GO:0016476 30 0.078
synapse assembly GO:0007416 143 0.078
regulation of cell cycle GO:0051726 291 0.077
actin filament polymerization GO:0030041 27 0.077
actin cytoskeleton organization GO:0030036 206 0.077
Human
nephron epithelium development GO:0072009 3 0.076
compound eye photoreceptor development GO:0042051 78 0.075
cytosolic calcium ion homeostasis GO:0051480 11 0.075
regulation of protein phosphorylation GO:0001932 64 0.075
connective tissue development GO:0061448 3 0.072
axis specification GO:0009798 167 0.072
striated muscle cell differentiation GO:0051146 90 0.072
cardiac cell fate specification GO:0060912 10 0.072
photoreceptor cell development GO:0042461 96 0.072
blastoderm segmentation GO:0007350 159 0.072
larval development GO:0002164 104 0.072
regulation of cell differentiation GO:0045595 302 0.071
Human
inter male aggressive behavior GO:0002121 60 0.071
neuron fate commitment GO:0048663 50 0.070
leg disc development GO:0035218 92 0.070
immune system process GO:0002376 347 0.070
negative regulation of axon extension GO:0030517 3 0.069
regulation of cellular protein metabolic process GO:0032268 243 0.069
negative regulation of cell death GO:0060548 81 0.069
cellular response to fibroblast growth factor stimulus GO:0044344 10 0.069
camera type eye development GO:0043010 4 0.068
positive regulation of cellular component biogenesis GO:0044089 80 0.066
establishment of cell polarity GO:0030010 40 0.066
Mouse
lamellipodium organization GO:0097581 21 0.066
positive regulation of axonogenesis GO:0050772 2 0.066
catabolic process GO:0009056 409 0.065
meiotic cell cycle process GO:1903046 132 0.064
eye photoreceptor cell development GO:0042462 81 0.064
negative regulation of signal transduction GO:0009968 206 0.064
regulation of actin cytoskeleton organization GO:0032956 42 0.064
wnt signaling pathway GO:0016055 98 0.064
anterior posterior axis specification embryo GO:0008595 103 0.064
positive regulation of rna biosynthetic process GO:1902680 266 0.063
axonal defasciculation GO:0007414 12 0.063
neural retina development GO:0003407 4 0.063
tissue migration GO:0090130 155 0.063
morphogenesis of embryonic epithelium GO:0016331 94 0.063
Mouse
cell growth GO:0016049 108 0.062
central nervous system development GO:0007417 201 0.060
body morphogenesis GO:0010171 2 0.060
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.060
gland morphogenesis GO:0022612 145 0.060
nephron morphogenesis GO:0072028 3 0.060
defense response to bacterium GO:0042742 178 0.059
negative regulation of cytoskeleton organization GO:0051494 30 0.059
protein localization GO:0008104 284 0.059
regulation of stress activated protein kinase signaling cascade GO:0070302 42 0.059
positive regulation of axon extension GO:0045773 2 0.059
epithelial cell migration GO:0010631 148 0.058
spermatogenesis GO:0007283 200 0.058
regulation of cellular component movement GO:0051270 42 0.058
embryonic axis specification GO:0000578 107 0.058
positive regulation of cytosolic calcium ion concentration GO:0007204 10 0.057
positive regulation of cell communication GO:0010647 250 0.056
phagocytosis GO:0006909 215 0.055
open tracheal system development GO:0007424 204 0.055
asymmetric neuroblast division GO:0055059 33 0.055
gonad morphogenesis GO:0035262 7 0.055
regulation of protein metabolic process GO:0051246 256 0.054
positive regulation of multicellular organismal process GO:0051240 143 0.054
Human
secretion GO:0046903 109 0.054
stem cell maintenance GO:0019827 67 0.054
muscle organ development GO:0007517 127 0.054
formation of organ boundary GO:0010160 30 0.053
response to bacterium GO:0009617 198 0.053
regulation of protein modification process GO:0031399 112 0.053
positive regulation of nervous system development GO:0051962 69 0.053
Human
r7 cell development GO:0045467 14 0.053
regulation of response to external stimulus GO:0032101 115 0.053
establishment of planar polarity GO:0001736 87 0.053
Mouse
actin polymerization or depolymerization GO:0008154 31 0.052
intracellular transport GO:0046907 228 0.052
response to fibroblast growth factor GO:0071774 10 0.052
oocyte construction GO:0007308 112 0.052
embryonic organ development GO:0048568 50 0.051
Mouse
imaginal disc derived wing vein morphogenesis GO:0008586 44 0.051
protein phosphorylation GO:0006468 169 0.050
regulation of cell shape GO:0008360 113 0.050
head involution GO:0008258 35 0.050
gastrulation with mouth forming first GO:0001703 36 0.050
positive regulation of biosynthetic process GO:0009891 316 0.049
enzyme linked receptor protein signaling pathway GO:0007167 179 0.049
regulation of apoptotic process GO:0042981 130 0.048
endocytosis GO:0006897 310 0.048
nuclear division GO:0000280 332 0.047
programmed cell death GO:0012501 257 0.046
oocyte axis specification GO:0007309 108 0.046
cuticle pattern formation GO:0035017 27 0.046
response to endogenous stimulus GO:0009719 119 0.046
chaeta development GO:0022416 97 0.046
positive regulation of response to stimulus GO:0048584 323 0.045
anterior posterior axis specification GO:0009948 109 0.045
macromolecular complex assembly GO:0065003 256 0.045
semaphorin plexin signaling pathway GO:0071526 4 0.044
regulation of cell projection organization GO:0031344 92 0.044
Human
cell fate specification GO:0001708 71 0.044
germ cell migration GO:0008354 43 0.044
negative regulation of cell differentiation GO:0045596 143 0.044
nephron tubule morphogenesis GO:0072078 3 0.044
positive regulation of gene expression GO:0010628 290 0.043
filopodium assembly GO:0046847 33 0.043
regulation of phosphorylation GO:0042325 147 0.043
columnar cuboidal epithelial cell development GO:0002066 249 0.042
apoptotic process GO:0006915 159 0.041
positive regulation of jun kinase activity GO:0043507 4 0.041
myotube differentiation GO:0014902 46 0.041
negative regulation of cell communication GO:0010648 223 0.041
negative regulation of catalytic activity GO:0043086 42 0.040
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.040
organelle assembly GO:0070925 198 0.040
regulation of embryonic development GO:0045995 68 0.040
Mouse
rho protein signal transduction GO:0007266 14 0.040
response to organic substance GO:0010033 284 0.040
Human
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 25 0.039
nephron tubule development GO:0072080 3 0.039
regulation of imaginal disc derived wing size GO:0044719 20 0.039
negative regulation of nervous system development GO:0051961 92 0.039
phosphorylation GO:0016310 294 0.039
regulation of cell cycle process GO:0010564 181 0.039
cell division GO:0051301 248 0.039
intracellular signal transduction GO:0035556 300 0.039
neuron projection extension involved in neuron projection guidance GO:1902284 10 0.038
protein maturation GO:0051604 71 0.038
regulation of multi organism process GO:0043900 131 0.038
regulation of wnt signaling pathway GO:0030111 68 0.038
neuron migration GO:0001764 5 0.038
negative regulation of cell development GO:0010721 62 0.038
nitrogen compound transport GO:0071705 85 0.038
defense response GO:0006952 300 0.037
cell cycle phase transition GO:0044770 140 0.037
organonitrogen compound metabolic process GO:1901564 318 0.037
renal system process GO:0003014 12 0.037
actin filament bundle assembly GO:0051017 26 0.037
single organism intracellular transport GO:1902582 207 0.037
positive regulation of molecular function GO:0044093 136 0.036
somatic muscle development GO:0007525 66 0.036
muscle cell development GO:0055001 50 0.036
periodic partitioning GO:0007365 29 0.036
reproductive system development GO:0061458 74 0.035
sex differentiation GO:0007548 81 0.035
regulation of cell growth GO:0001558 43 0.035
imaginal disc derived wing hair site selection GO:0035320 4 0.035
extrinsic apoptotic signaling pathway GO:0097191 1 0.035
positive regulation of cellular biosynthetic process GO:0031328 316 0.035
wing and notum subfield formation GO:0035309 13 0.035
non canonical wnt signaling pathway GO:0035567 8 0.035
Mouse
protein processing GO:0016485 68 0.034
positive regulation of rna metabolic process GO:0051254 271 0.034
long term memory GO:0007616 62 0.034
defense response to other organism GO:0098542 225 0.034
regulation of programmed cell death GO:0043067 152 0.034
defasciculation of motor neuron axon GO:0007415 8 0.034
g protein coupled receptor signaling pathway GO:0007186 136 0.034
larval lymph gland hemopoiesis GO:0035167 17 0.033
leg disc morphogenesis GO:0007478 80 0.033
small molecule metabolic process GO:0044281 305 0.033
positive regulation of nucleic acid templated transcription GO:1903508 266 0.033
fibroblast growth factor receptor signaling pathway GO:0008543 10 0.033
regulation of jnk cascade GO:0046328 40 0.032
hematopoietic or lymphoid organ development GO:0048534 57 0.032
organ formation GO:0048645 39 0.032
hemopoiesis GO:0030097 46 0.032
positive regulation of catalytic activity GO:0043085 118 0.032
gastrulation involving germ band extension GO:0010004 36 0.031
cellular amino acid metabolic process GO:0006520 61 0.030
positive regulation of cell differentiation GO:0045597 64 0.030
Human
maintenance of location GO:0051235 73 0.030
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.030
regulation of protein polymerization GO:0032271 28 0.030
positive regulation of developmental process GO:0051094 143 0.030
Human
negative regulation of rna biosynthetic process GO:1902679 240 0.029
organic substance catabolic process GO:1901575 308 0.029
negative regulation of epithelial cell proliferation GO:0050680 4 0.029
smoothened signaling pathway GO:0007224 49 0.029
development of primary female sexual characteristics GO:0046545 12 0.029
epithelial tube morphogenesis GO:0060562 88 0.029
Mouse
establishment of organelle localization GO:0051656 122 0.028
dendrite self avoidance GO:0070593 8 0.028
development of primary sexual characteristics GO:0045137 50 0.027
formation of anatomical boundary GO:0048859 37 0.027
camera type eye morphogenesis GO:0048593 2 0.027
lamellipodium assembly GO:0030032 21 0.027
regulation of stress activated mapk cascade GO:0032872 41 0.027
syncytium formation by plasma membrane fusion GO:0000768 43 0.027
immune response GO:0006955 246 0.026
negative regulation of nucleic acid templated transcription GO:1903507 240 0.026
mrna metabolic process GO:0016071 124 0.026
regulation of cellular amine metabolic process GO:0033238 3 0.026
regulation of protein complex assembly GO:0043254 42 0.026
meiotic cell cycle GO:0051321 171 0.026
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.026
regulation of epithelial cell differentiation GO:0030856 4 0.026
positive regulation of signaling GO:0023056 243 0.026
wnt signaling pathway planar cell polarity pathway GO:0060071 6 0.026
Mouse
nucleus localization GO:0051647 34 0.026
response to oxygen containing compound GO:1901700 200 0.026
Human
ameboidal type cell migration GO:0001667 151 0.026
epithelial cell morphogenesis GO:0003382 25 0.026
regulation of cell size GO:0008361 63 0.026
negative regulation of apoptotic process GO:0043066 63 0.026
glial cell migration GO:0008347 31 0.025
cellular amine metabolic process GO:0044106 12 0.025
regulation of stem cell differentiation GO:2000736 14 0.025
instar larval development GO:0002168 55 0.025
oxoacid metabolic process GO:0043436 103 0.025
immune system development GO:0002520 57 0.025
cell cell adhesion GO:0098609 26 0.025
oocyte development GO:0048599 124 0.025
regulation of extent of cell growth GO:0061387 8 0.025
negative regulation of cellular component organization GO:0051129 108 0.025
regulation of chemotaxis GO:0050920 12 0.025
positive regulation of transcription dna templated GO:0045893 266 0.024
cation transport GO:0006812 110 0.024
negative regulation of biosynthetic process GO:0009890 277 0.024
single organism cellular localization GO:1902580 180 0.024
positive regulation of cell adhesion GO:0045785 10 0.024
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.024
nephron tubule formation GO:0072079 3 0.023
synaptic transmission GO:0007268 288 0.023
nucleobase containing compound catabolic process GO:0034655 165 0.023
nucleotide catabolic process GO:0009166 109 0.023
regulation of locomotion GO:0040012 42 0.023
positive regulation of cellular protein metabolic process GO:0032270 118 0.023
forebrain development GO:0030900 2 0.023
regulation of hydrolase activity GO:0051336 97 0.023
positive regulation of signal transduction GO:0009967 223 0.023
regulation of cell cell adhesion GO:0022407 21 0.023
regulation of dendrite morphogenesis GO:0048814 28 0.023
localization of cell GO:0051674 257 0.023
Human
branching involved in open tracheal system development GO:0060446 45 0.023
organonitrogen compound biosynthetic process GO:1901566 117 0.023
multi organism behavior GO:0051705 175 0.023
mesoderm development GO:0007498 78 0.023
actin filament based process GO:0030029 220 0.023
Human
kidney epithelium development GO:0072073 3 0.023
chaeta morphogenesis GO:0008407 42 0.023
protein complex biogenesis GO:0070271 201 0.023
response to alcohol GO:0097305 95 0.022
skeletal muscle fiber development GO:0048741 3 0.022
positive regulation of phosphate metabolic process GO:0045937 139 0.022
cardiac cell fate commitment GO:0060911 17 0.022
regulation of cardioblast differentiation GO:0051890 9 0.022
extracellular matrix organization GO:0030198 32 0.022
female gonad development GO:0008585 12 0.022
cardioblast cell fate commitment GO:0042684 14 0.022
ras protein signal transduction GO:0007265 88 0.022
positive regulation of cell motility GO:2000147 3 0.022
protein complex assembly GO:0006461 200 0.022
determination of bilateral symmetry GO:0009855 13 0.021
secretion by cell GO:0032940 101 0.021
dorsal ventral pattern formation imaginal disc GO:0007450 51 0.021
lymph gland development GO:0048542 28 0.021
hemocyte differentiation GO:0042386 38 0.021
regulation of epithelial cell proliferation GO:0050678 4 0.021
convergent extension GO:0060026 2 0.021
Mouse
cytokinesis GO:0000910 90 0.021
positive regulation of synapse assembly GO:0051965 29 0.021
cell cell junction assembly GO:0007043 38 0.021
stem cell development GO:0048864 79 0.021
gonad development GO:0008406 50 0.021
negative chemotaxis GO:0050919 15 0.021
negative regulation of programmed cell death GO:0043069 72 0.021
developmental cell growth GO:0048588 52 0.020
guanosine containing compound catabolic process GO:1901069 74 0.020
detection of stimulus involved in sensory perception GO:0050906 92 0.020
positive regulation of phosphorus metabolic process GO:0010562 139 0.020
regulation of synapse structure and activity GO:0050803 128 0.020
actin cytoskeleton reorganization GO:0031532 22 0.020
Human
cytokinetic cell separation GO:0000920 1 0.020
positive regulation of protein modification process GO:0031401 58 0.020
regulation of actin polymerization or depolymerization GO:0008064 27 0.020
organic acid metabolic process GO:0006082 103 0.020
imaginal disc growth GO:0007446 37 0.020
organic cyclic compound catabolic process GO:1901361 168 0.020
regulation of catabolic process GO:0009894 170 0.020
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.020
meiosis i GO:0007127 59 0.020
positive regulation of growth GO:0045927 75 0.020
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.020
establishment of proximal distal cell polarity GO:0022606 4 0.020
regulation of actin filament based process GO:0032970 42 0.020
cellular catabolic process GO:0044248 372 0.019
initiation of dorsal closure GO:0007392 12 0.019
regulation of catalytic activity GO:0050790 185 0.019
regulation of peptidase activity GO:0052547 39 0.019
mesoderm morphogenesis GO:0048332 22 0.019
negative regulation of sequestering of calcium ion GO:0051283 2 0.019
ribonucleotide catabolic process GO:0009261 109 0.019
cilium assembly GO:0042384 38 0.019
regulation of actin filament polymerization GO:0030833 25 0.019
tracheal outgrowth open tracheal system GO:0007426 18 0.019
regulation of microtubule cytoskeleton organization GO:0070507 41 0.019
positive regulation of apoptotic signaling pathway GO:2001235 4 0.019
cell junction assembly GO:0034329 42 0.019
regulation of protein serine threonine kinase activity GO:0071900 25 0.019
extracellular structure organization GO:0043062 46 0.019
single organism biosynthetic process GO:0044711 206 0.019
positive regulation of developmental growth GO:0048639 62 0.019
negative regulation of multicellular organismal process GO:0051241 142 0.018
ventral furrow formation GO:0007370 17 0.018
amine metabolic process GO:0009308 12 0.018
negative regulation of cellular protein metabolic process GO:0032269 85 0.018
cell cell junction organization GO:0045216 55 0.018
developmental programmed cell death GO:0010623 138 0.018
syncytium formation GO:0006949 43 0.018
negative regulation of neuron differentiation GO:0045665 16 0.018
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.018
developmental maturation GO:0021700 172 0.018
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.018
regulation of protein kinase activity GO:0045859 51 0.018
protein polymerization GO:0051258 42 0.018
compound eye retinal cell programmed cell death GO:0046667 23 0.018
regulation of mapk cascade GO:0043408 92 0.018
heart induction GO:0003129 3 0.018
negative regulation of response to stimulus GO:0048585 258 0.018
heterocycle catabolic process GO:0046700 166 0.018
regulation of cellular localization GO:0060341 136 0.018
regulation of hormone levels GO:0010817 40 0.018
glycosyl compound catabolic process GO:1901658 112 0.018
positive regulation of phosphorylation GO:0042327 87 0.018
cell fate specification involved in pattern specification GO:0060573 8 0.018
establishment of nucleus localization GO:0040023 26 0.017
segment polarity determination GO:0007367 25 0.017
cuticle development GO:0042335 86 0.017
male gamete generation GO:0048232 201 0.017
photoreceptor cell fate commitment GO:0046552 41 0.017
detection of visible light GO:0009584 38 0.017

otk disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.049
cancer DOID:162 0 0.032
disease of cellular proliferation DOID:14566 0 0.032
organ system cancer DOID:0050686 0 0.032
sensory system disease DOID:0050155 0 0.028
nervous system disease DOID:863 0 0.028
cardiovascular system disease DOID:1287 0 0.022
heart conduction disease DOID:10273 0 0.022
eye and adnexa disease DOID:1492 0 0.019