Drosophila melanogaster

87 known processes

NiPp1 (Dmel_CG8980)

Nuclear inhibitor of Protein phosphatase 1

(Aliases: NiPp-1,NIPP-1Dm,NIPP1,NIPP1Dm,CG8980,Dmel\CG8980,nipp1)

NiPp1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
chromosome segregation GO:0007059 157 0.750
organelle fission GO:0048285 340 0.447
spindle assembly GO:0051225 80 0.386
spindle assembly involved in mitosis GO:0090307 50 0.312
meiotic nuclear division GO:0007126 151 0.288
sister chromatid segregation GO:0000819 92 0.242
chromosome organization GO:0051276 360 0.234
mitotic spindle organization GO:0007052 220 0.210
mitotic sister chromatid segregation GO:0000070 87 0.205
protein complex biogenesis GO:0070271 201 0.201
locomotory behavior GO:0007626 176 0.196
cellular response to dna damage stimulus GO:0006974 223 0.196
meiotic cell cycle GO:0051321 171 0.193
dna conformation change GO:0071103 105 0.190
axon development GO:0061564 297 0.187
cellular protein modification process GO:0006464 438 0.167
organelle assembly GO:0070925 198 0.165
axonogenesis GO:0007409 290 0.156
meiotic chromosome segregation GO:0045132 59 0.138
protein dephosphorylation GO:0006470 27 0.135
regulation of cell cycle GO:0051726 291 0.130
macromolecular complex assembly GO:0065003 256 0.127
female meiotic division GO:0007143 70 0.123
axon guidance GO:0007411 233 0.114
rna processing GO:0006396 147 0.111
microtubule cytoskeleton organization involved in mitosis GO:1902850 52 0.106
nuclear division GO:0000280 332 0.106
regulation of intracellular signal transduction GO:1902531 236 0.105
mitotic chromosome condensation GO:0007076 22 0.103
cellular catabolic process GO:0044248 372 0.102
central nervous system development GO:0007417 201 0.102
regulation of sister chromatid segregation GO:0033045 28 0.102
multi multicellular organism process GO:0044706 123 0.100
dna metabolic process GO:0006259 227 0.098
meiotic cell cycle process GO:1903046 132 0.090
regulation of mapk cascade GO:0043408 92 0.090
dna packaging GO:0006323 91 0.086
reproductive behavior GO:0019098 122 0.081
columnar cuboidal epithelial cell development GO:0002066 249 0.080
cell migration GO:0016477 238 0.079
regulation of cellular protein metabolic process GO:0032268 243 0.079
spindle organization GO:0007051 253 0.077
mitotic sister chromatid separation GO:0051306 30 0.077
regulation of metaphase anaphase transition of cell cycle GO:1902099 26 0.073
negative regulation of phosphate metabolic process GO:0045936 45 0.071
regulation of protein dephosphorylation GO:0035304 5 0.069
regulation of organelle organization GO:0033043 196 0.069
protein complex assembly GO:0006461 200 0.066
regulation of cellular component biogenesis GO:0044087 201 0.065
regulation of mitotic metaphase anaphase transition GO:0030071 26 0.065
circadian rhythm GO:0007623 105 0.063
dna replication GO:0006260 48 0.062
macromolecule catabolic process GO:0009057 161 0.061
dna dependent dna replication maintenance of fidelity GO:0045005 0 0.061
chromosome separation GO:0051304 42 0.060
cell proliferation GO:0008283 299 0.059
Mouse
regulation of protein metabolic process GO:0051246 256 0.059
regulation of phosphate metabolic process GO:0019220 210 0.058
neurological system process GO:0050877 358 0.057
spindle assembly involved in female meiosis i GO:0007057 5 0.057
carbohydrate derivative metabolic process GO:1901135 217 0.057
chemotaxis GO:0006935 249 0.055
intracellular signal transduction GO:0035556 300 0.055
positive regulation of signal transduction GO:0009967 223 0.055
organic substance catabolic process GO:1901575 308 0.054
circadian behavior GO:0048512 76 0.054
protein modification process GO:0036211 438 0.052
mitotic nuclear division GO:0007067 213 0.051
dephosphorylation GO:0016311 51 0.050
negative regulation of cell communication GO:0010648 223 0.050
multi organism reproductive behavior GO:0044705 121 0.050
mrna metabolic process GO:0016071 124 0.050
regulation of mitotic sister chromatid separation GO:0010965 28 0.048
regulation of mitotic sister chromatid segregation GO:0033047 28 0.048
mrna processing GO:0006397 104 0.047
negative regulation of organelle organization GO:0010639 56 0.047
heterocycle catabolic process GO:0046700 166 0.045
centrosome organization GO:0051297 163 0.045
brain development GO:0007420 120 0.045
metaphase anaphase transition of cell cycle GO:0044784 28 0.044
establishment or maintenance of cell polarity GO:0007163 167 0.042
protein complex disassembly GO:0043241 36 0.041
erk1 and erk2 cascade GO:0070371 39 0.040
taxis GO:0042330 304 0.040
regulation of circadian rhythm GO:0042752 49 0.039
regulation of transport GO:0051049 181 0.039
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.039
regulation of small gtpase mediated signal transduction GO:0051056 93 0.039
centrosome duplication GO:0051298 121 0.039
ras protein signal transduction GO:0007265 88 0.039
dna damage checkpoint GO:0000077 78 0.039
regulation of protein catabolic process GO:0042176 55 0.038
axis specification GO:0009798 167 0.038
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.038
negative regulation of cellular protein metabolic process GO:0032269 85 0.038
dendrite development GO:0016358 204 0.037
regulation of immune response GO:0050776 118 0.036
endocytosis GO:0006897 310 0.036
regulation of molecular function GO:0065009 217 0.036
covalent chromatin modification GO:0016569 106 0.035
chromosome condensation GO:0030261 41 0.035
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process GO:0031145 30 0.035
phosphorylation GO:0016310 294 0.035
immune response GO:0006955 246 0.035
nucleobase containing small molecule metabolic process GO:0055086 174 0.035
enzyme linked receptor protein signaling pathway GO:0007167 179 0.035
establishment of chromosome localization GO:0051303 20 0.034
dendrite morphogenesis GO:0048813 199 0.034
chromatin organization GO:0006325 207 0.034
negative regulation of cellular component organization GO:0051129 108 0.034
modification dependent protein catabolic process GO:0019941 78 0.033
cellularization GO:0007349 90 0.033
epithelial cell differentiation GO:0030855 322 0.033
positive regulation of signaling GO:0023056 243 0.032
cellular macromolecular complex assembly GO:0034622 153 0.032
cellular protein complex assembly GO:0043623 71 0.032
hindgut morphogenesis GO:0007442 58 0.032
chromatin modification GO:0016568 147 0.032
regulation of cytoskeleton organization GO:0051493 89 0.031
histone modification GO:0016570 106 0.031
regulation of phosphorylation GO:0042325 147 0.031
positive regulation of cell communication GO:0010647 250 0.031
regulation of erk1 and erk2 cascade GO:0070372 39 0.031
microtubule organizing center organization GO:0031023 168 0.030
respiratory system development GO:0060541 213 0.030
negative regulation of signal transduction GO:0009968 206 0.030
positive regulation of apoptotic signaling pathway GO:2001235 4 0.030
embryonic pattern specification GO:0009880 174 0.030
regulation of phosphorus metabolic process GO:0051174 210 0.029
regulation of protein modification process GO:0031399 112 0.029
positive regulation of cellular protein metabolic process GO:0032270 118 0.029
dna integrity checkpoint GO:0031570 81 0.029
regulation of microtubule polymerization or depolymerization GO:0031110 27 0.029
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.029
regulation of cell division GO:0051302 72 0.029
energy derivation by oxidation of organic compounds GO:0015980 32 0.028
cellular macromolecule catabolic process GO:0044265 136 0.028
multicellular organismal reproductive behavior GO:0033057 110 0.028
protein polymerization GO:0051258 42 0.028
neuron projection guidance GO:0097485 241 0.027
organelle localization GO:0051640 148 0.027
multi organism behavior GO:0051705 175 0.027
defense response to other organism GO:0098542 225 0.027
secretion GO:0046903 109 0.025
sensory perception of mechanical stimulus GO:0050954 72 0.025
regulation of proteasomal protein catabolic process GO:0061136 39 0.025
catabolic process GO:0009056 409 0.025
negative regulation of cellular metabolic process GO:0031324 382 0.025
rhythmic process GO:0048511 106 0.025
negative regulation of catalytic activity GO:0043086 42 0.025
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.025
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.024
cell division GO:0051301 248 0.024
telomere capping GO:0016233 11 0.024
meiosis i GO:0007127 59 0.024
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.024
small gtpase mediated signal transduction GO:0007264 88 0.023
localization of cell GO:0051674 257 0.023
single organism behavior GO:0044708 391 0.023
positive regulation of protein metabolic process GO:0051247 128 0.023
transcription from rna polymerase ii promoter GO:0006366 368 0.023
sensory perception GO:0007600 196 0.023
negative regulation of protein metabolic process GO:0051248 85 0.023
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 44 0.023
regulation of chromosome organization GO:0033044 64 0.023
positive regulation of biosynthetic process GO:0009891 316 0.023
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.023
regulation of cell death GO:0010941 173 0.023
regulation of dna metabolic process GO:0051052 34 0.022
negative regulation of gene expression GO:0010629 387 0.022
organonitrogen compound metabolic process GO:1901564 318 0.022
negative regulation of mitotic sister chromatid separation GO:2000816 13 0.022
sister chromatid cohesion GO:0007062 18 0.022
dna dependent dna replication GO:0006261 17 0.022
positive regulation of phosphorylation GO:0042327 87 0.021
negative regulation of chromosome segregation GO:0051985 14 0.021
macromolecular complex disassembly GO:0032984 37 0.021
positive regulation of cellular component biogenesis GO:0044089 80 0.021
regulation of localization GO:0032879 275 0.021
intracellular transport GO:0046907 228 0.021
microtubule based movement GO:0007018 51 0.021
regulation of ras protein signal transduction GO:0046578 93 0.021
cellular component assembly involved in morphogenesis GO:0010927 151 0.020
regulation of protein complex disassembly GO:0043244 29 0.020
regulation of catalytic activity GO:0050790 185 0.020
development of primary sexual characteristics GO:0045137 50 0.020
appendage development GO:0048736 401 0.020
cognition GO:0050890 141 0.020
regulation of proteolysis GO:0030162 87 0.020
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.020
segmentation GO:0035282 207 0.019
erbb signaling pathway GO:0038127 58 0.019
reproductive system development GO:0061458 74 0.019
ovarian follicle cell development GO:0030707 248 0.019
proteolysis GO:0006508 192 0.019
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.019
negative regulation of mitotic sister chromatid segregation GO:0033048 13 0.019
microtubule bundle formation GO:0001578 27 0.019
regulation of immune system process GO:0002682 176 0.018
phagocytosis GO:0006909 215 0.018
regulation of wnt signaling pathway GO:0030111 68 0.018
regulation of protein polymerization GO:0032271 28 0.018
negative regulation of biosynthetic process GO:0009890 277 0.017
negative regulation of signaling GO:0023057 219 0.017
positive regulation of nucleic acid templated transcription GO:1903508 266 0.017
establishment of localization in cell GO:0051649 402 0.017
protein depolymerization GO:0051261 31 0.017
sex differentiation GO:0007548 81 0.017
negative regulation of sister chromatid segregation GO:0033046 13 0.016
positive regulation of erk1 and erk2 cascade GO:0070374 36 0.016
positive regulation of intracellular signal transduction GO:1902533 116 0.016
positive regulation of rna biosynthetic process GO:1902680 266 0.016
mitotic cell cycle phase transition GO:0044772 138 0.016
appendage morphogenesis GO:0035107 397 0.016
embryonic hindgut morphogenesis GO:0048619 48 0.016
organic substance transport GO:0071702 257 0.016
immune response activating signal transduction GO:0002757 2 0.016
metaphase anaphase transition of mitotic cell cycle GO:0007091 28 0.016
regulation of nuclear division GO:0051783 58 0.016
dna replication checkpoint GO:0000076 8 0.016
reciprocal meiotic recombination GO:0007131 19 0.016
negative regulation of cell cycle GO:0045786 116 0.016
negative regulation of neuron death GO:1901215 18 0.015
mitotic cytokinesis GO:0000281 50 0.015
protein localization GO:0008104 284 0.015
protein catabolic process GO:0030163 101 0.015
response to external biotic stimulus GO:0043207 293 0.015
regulation of mitotic cell cycle phase transition GO:1901990 130 0.015
positive regulation of response to stimulus GO:0048584 323 0.015
dna double strand break processing GO:0000729 3 0.015
mapk cascade GO:0000165 107 0.015
gliogenesis GO:0042063 80 0.015
signal transduction by phosphorylation GO:0023014 107 0.015
dna repair GO:0006281 54 0.015
maintenance of location GO:0051235 73 0.015
negative regulation of cellular biosynthetic process GO:0031327 277 0.014
purine ribonucleoside metabolic process GO:0046128 127 0.014
pole cell formation GO:0007279 19 0.014
establishment of rna localization GO:0051236 47 0.014
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 37 0.014
regulation of chromosome segregation GO:0051983 32 0.014
larval development GO:0002164 104 0.014
stem cell division GO:0017145 69 0.014
negative regulation of mitotic metaphase anaphase transition GO:0045841 13 0.014
regulation of catabolic process GO:0009894 170 0.014
cellular protein catabolic process GO:0044257 83 0.014
positive regulation of transcription dna templated GO:0045893 266 0.014
positive regulation of protein catabolic process GO:0045732 34 0.014
generation of precursor metabolites and energy GO:0006091 42 0.014
regulation of protein depolymerization GO:1901879 27 0.014
post embryonic appendage morphogenesis GO:0035120 385 0.013
cytoskeleton dependent intracellular transport GO:0030705 44 0.013
positive regulation of ras protein signal transduction GO:0046579 43 0.013
glycosyl compound metabolic process GO:1901657 127 0.013
proteasomal protein catabolic process GO:0010498 59 0.013
regulation of cellular amino acid metabolic process GO:0006521 0 0.013
regulation of nervous system development GO:0051960 248 0.013
purine ribonucleotide metabolic process GO:0009150 145 0.013
nitrogen compound transport GO:0071705 85 0.013
imaginal disc derived appendage development GO:0048737 399 0.013
mitotic spindle checkpoint GO:0071174 11 0.013
cell death GO:0008219 279 0.013
aromatic compound catabolic process GO:0019439 166 0.013
negative regulation of phosphorus metabolic process GO:0010563 45 0.013
nucleocytoplasmic transport GO:0006913 72 0.013
response to other organism GO:0051707 293 0.012
small molecule metabolic process GO:0044281 305 0.012
negative regulation of cell division GO:0051782 17 0.012
epithelial cell development GO:0002064 274 0.012
signal transduction in response to dna damage GO:0042770 3 0.012
mitotic g2 m transition checkpoint GO:0044818 70 0.012
embryonic axis specification GO:0000578 107 0.012
organophosphate metabolic process GO:0019637 195 0.012
positive regulation of phosphate metabolic process GO:0045937 139 0.012
regulation of apoptotic process GO:0042981 130 0.012
microtubule polymerization or depolymerization GO:0031109 39 0.012
hindgut development GO:0061525 58 0.012
embryo development ending in birth or egg hatching GO:0009792 152 0.012
protein acylation GO:0043543 42 0.012
negative regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032435 16 0.012
mitotic spindle assembly checkpoint GO:0007094 11 0.012
negative regulation of mitotic cell cycle GO:0045930 109 0.012
modification dependent macromolecule catabolic process GO:0043632 79 0.012
negative regulation of intracellular signal transduction GO:1902532 57 0.012
single organism biosynthetic process GO:0044711 206 0.012
learning or memory GO:0007611 141 0.012
regulation of neuron projection development GO:0010975 69 0.012
imaginal disc derived appendage morphogenesis GO:0035114 395 0.012
vesicle mediated transport GO:0016192 381 0.011
cell maturation GO:0048469 144 0.011
cell motility GO:0048870 251 0.011
positive regulation of phosphorus metabolic process GO:0010562 139 0.011
negative regulation of protein modification process GO:0031400 29 0.011
camera type eye development GO:0043010 4 0.011
response to light stimulus GO:0009416 124 0.011
organic cyclic compound catabolic process GO:1901361 168 0.011
mitotic spindle elongation GO:0000022 81 0.011
morphogenesis of an epithelium GO:0002009 276 0.011
cell cycle arrest GO:0007050 4 0.011
cellular protein complex disassembly GO:0043624 35 0.011
regulation of cellular protein catabolic process GO:1903362 44 0.011
positive regulation of immune response GO:0050778 63 0.011
negative regulation of proteolysis GO:0045861 31 0.011
wing disc morphogenesis GO:0007472 344 0.011
atp dependent chromatin remodeling GO:0043044 22 0.011
meiotic dna double strand break formation involved in reciprocal meiotic recombination GO:0010780 1 0.011
single organism catabolic process GO:0044712 228 0.011
positive regulation of cellular component organization GO:0051130 156 0.010
cellular response to chemical stimulus GO:0070887 199 0.010
nucleotide metabolic process GO:0009117 161 0.010
protein phosphorylation GO:0006468 169 0.010
ubiquitin dependent protein catabolic process GO:0006511 78 0.010
nuclear transport GO:0051169 72 0.010

NiPp1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.026
nervous system disease DOID:863 0 0.026
cancer DOID:162 0 0.013
disease of cellular proliferation DOID:14566 0 0.013
sensory system disease DOID:0050155 0 0.012