Drosophila melanogaster

24 known processes

Gpdh (Dmel_CG9042)

Glycerol 3 phosphate dehydrogenase

(Aliases: gpdh,Dmel\CG9042,GPDA,sn-Gpdh,DmG3PDH,alpha-GPD,GPD,alphaGpdh,alpha-GPDH,G3PDH,alphaGpdh-1,DROGPDHA,GAPDH,Gpd,alphaGpd,Gdh,CG9042,alpha-GPDH-1,GPDH,alphaGPDH,alpha-Gpdh)

Gpdh biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
adult behavior GO:0030534 137 0.979
carbohydrate biosynthetic process GO:0016051 17 0.549
Mouse
energy derivation by oxidation of organic compounds GO:0015980 32 0.527
Mouse
nad metabolic process GO:0019674 1 0.448
oxidation reduction process GO:0055114 123 0.374
Mouse
determination of adult lifespan GO:0008340 137 0.341
single organism behavior GO:0044708 391 0.312
striated muscle cell development GO:0055002 50 0.284
somatic muscle development GO:0007525 66 0.280
carbohydrate metabolic process GO:0005975 82 0.274
Mouse
cellular component assembly involved in morphogenesis GO:0010927 151 0.247
sarcomere organization GO:0045214 26 0.243
single organism biosynthetic process GO:0044711 206 0.240
Mouse
organophosphate metabolic process GO:0019637 195 0.234
Mouse
nucleobase containing small molecule metabolic process GO:0055086 174 0.201
muscle system process GO:0003012 21 0.189
striated muscle myosin thick filament assembly GO:0071688 3 0.183
multicellular organismal aging GO:0010259 140 0.167
organic substance catabolic process GO:1901575 308 0.163
Mouse
single organism carbohydrate metabolic process GO:0044723 72 0.156
Mouse
cellular lipid catabolic process GO:0044242 16 0.151
endocytosis GO:0006897 310 0.146
purine containing compound metabolic process GO:0072521 155 0.136
actin cytoskeleton organization GO:0030036 206 0.131
aging GO:0007568 143 0.130
melanin metabolic process GO:0006582 47 0.129
developmental growth GO:0048589 280 0.127
cell death GO:0008219 279 0.126
acetaldehyde metabolic process GO:0006117 5 0.118
organic substance transport GO:0071702 257 0.116
myofibril assembly GO:0030239 36 0.116
regulation of growth GO:0040008 233 0.114
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.114
lipid localization GO:0010876 54 0.111
glycerolipid catabolic process GO:0046503 3 0.110
camera type eye development GO:0043010 4 0.106
organic acid metabolic process GO:0006082 103 0.101
Mouse
organonitrogen compound metabolic process GO:1901564 318 0.098
regulation of cell cycle GO:0051726 291 0.096
protein complex biogenesis GO:0070271 201 0.095
lipid metabolic process GO:0006629 121 0.091
purine nucleoside metabolic process GO:0042278 127 0.086
nitrogen compound transport GO:0071705 85 0.085
single organism catabolic process GO:0044712 228 0.079
Mouse
catabolic process GO:0009056 409 0.076
Mouse
regulation of tube size open tracheal system GO:0035151 43 0.075
purine nucleoside biosynthetic process GO:0042451 3 0.074
protein complex assembly GO:0006461 200 0.073
cellular lipid metabolic process GO:0044255 83 0.073
cellular response to transforming growth factor beta stimulus GO:0071560 18 0.072
oxoacid metabolic process GO:0043436 103 0.071
Mouse
growth GO:0040007 359 0.070
wound healing GO:0042060 75 0.064
actin filament based process GO:0030029 220 0.062
cellular polysaccharide metabolic process GO:0044264 11 0.062
flight behavior GO:0007629 26 0.061
glycosyl compound metabolic process GO:1901657 127 0.060
response to transforming growth factor beta GO:0071559 18 0.059
epithelial cell differentiation GO:0030855 322 0.059
carbohydrate derivative metabolic process GO:1901135 217 0.059
Mouse
generation of precursor metabolites and energy GO:0006091 42 0.055
Mouse
small molecule metabolic process GO:0044281 305 0.054
Mouse
localization of cell GO:0051674 257 0.052
glycerol 3 phosphate metabolic process GO:0006072 2 0.052
Mouse
striated muscle contraction GO:0006941 5 0.051
cellular nitrogen compound catabolic process GO:0044270 165 0.050
regulation of multicellular organismal development GO:2000026 414 0.050
organic hydroxy compound metabolic process GO:1901615 83 0.050
cellular amino acid metabolic process GO:0006520 61 0.049
ovarian follicle cell development GO:0030707 248 0.049
striated muscle cell differentiation GO:0051146 90 0.048
pyridine containing compound metabolic process GO:0072524 3 0.048
adult locomotory behavior GO:0008344 76 0.048
positive regulation of catabolic process GO:0009896 105 0.048
Mouse
purine ribonucleoside metabolic process GO:0046128 127 0.047
regulation of cell death GO:0010941 173 0.046
gonad development GO:0008406 50 0.045
phagocytosis GO:0006909 215 0.045
acylglycerol biosynthetic process GO:0046463 2 0.045
positive regulation of transport GO:0051050 92 0.044
glucose metabolic process GO:0006006 5 0.044
Mouse
ribonucleoside metabolic process GO:0009119 127 0.042
negative regulation of cell cycle GO:0045786 116 0.042
primary alcohol metabolic process GO:0034308 2 0.041
lipid storage GO:0019915 38 0.041
telencephalon development GO:0021537 2 0.041
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.040
neutral lipid catabolic process GO:0046461 3 0.039
regulation of purine nucleotide metabolic process GO:1900542 62 0.039
cellular catabolic process GO:0044248 372 0.039
Mouse
ribose phosphate metabolic process GO:0019693 145 0.039
epidermis development GO:0008544 65 0.038
negative regulation of biosynthetic process GO:0009890 277 0.037
regulation of cell differentiation GO:0045595 302 0.037
response to hexose GO:0009746 3 0.037
nucleotide biosynthetic process GO:0009165 34 0.036
imaginal disc derived appendage development GO:0048737 399 0.036
positive regulation of cellular biosynthetic process GO:0031328 316 0.035
monosaccharide metabolic process GO:0005996 9 0.034
Mouse
response to monosaccharide GO:0034284 4 0.034
cytoplasmic transport nurse cell to oocyte GO:0007303 12 0.034
behavioral response to ethanol GO:0048149 49 0.034
cellular macromolecular complex assembly GO:0034622 153 0.034
vesicle mediated transport GO:0016192 381 0.034
heterocycle catabolic process GO:0046700 166 0.034
columnar cuboidal epithelial cell development GO:0002066 249 0.034
nucleocytoplasmic transport GO:0006913 72 0.034
skeletal muscle myosin thick filament assembly GO:0030241 3 0.034
electron transport chain GO:0022900 14 0.033
Mouse
cell migration GO:0016477 238 0.033
hexose metabolic process GO:0019318 8 0.033
Mouse
myosin filament assembly GO:0031034 5 0.033
brain development GO:0007420 120 0.033
positive regulation of catalytic activity GO:0043085 118 0.032
nucleoside triphosphate metabolic process GO:0009141 120 0.031
wing disc morphogenesis GO:0007472 344 0.031
nucleoside phosphate metabolic process GO:0006753 162 0.030
transforming growth factor beta receptor signaling pathway GO:0007179 16 0.030
homeostatic process GO:0042592 199 0.030
actomyosin structure organization GO:0031032 56 0.030
multi organism behavior GO:0051705 175 0.029
nucleoside metabolic process GO:0009116 127 0.029
protein localization GO:0008104 284 0.029
defense response GO:0006952 300 0.028
body morphogenesis GO:0010171 2 0.028
activation of cysteine type endopeptidase activity involved in apoptotic process GO:0006919 16 0.028
polysaccharide metabolic process GO:0005976 11 0.026
regulation of cellular catabolic process GO:0031329 157 0.026
Mouse
fatty acid metabolic process GO:0006631 20 0.026
muscle tissue morphogenesis GO:0060415 2 0.026
negative regulation of cellular biosynthetic process GO:0031327 277 0.026
ribonucleoside biosynthetic process GO:0042455 3 0.025
pyruvate metabolic process GO:0006090 7 0.025
Mouse
regulation of apoptotic process GO:0042981 130 0.024
skin development GO:0043588 65 0.024
muscle cell development GO:0055001 50 0.024
cellular respiration GO:0045333 26 0.023
Mouse
skeletal muscle fiber development GO:0048741 3 0.023
carbohydrate derivative catabolic process GO:1901136 118 0.023
response to wounding GO:0009611 94 0.023
regulation of catalytic activity GO:0050790 185 0.023
muscle contraction GO:0006936 13 0.022
larval development GO:0002164 104 0.022
response to organonitrogen compound GO:0010243 75 0.022
Mouse
embryo development ending in birth or egg hatching GO:0009792 152 0.022
purine nucleoside triphosphate metabolic process GO:0009144 119 0.022
regulation of phosphate metabolic process GO:0019220 210 0.022
ribonucleoside catabolic process GO:0042454 112 0.022
maintenance of location GO:0051235 73 0.021
protein transport GO:0015031 155 0.021
digestive tract morphogenesis GO:0048546 127 0.021
organelle assembly GO:0070925 198 0.021
monocarboxylic acid metabolic process GO:0032787 29 0.021
Mouse
purine nucleotide metabolic process GO:0006163 146 0.021
polysaccharide biosynthetic process GO:0000271 7 0.020
monocarboxylic acid biosynthetic process GO:0072330 7 0.020
neuromuscular synaptic transmission GO:0007274 67 0.020
regionalization GO:0003002 416 0.020
transmembrane transport GO:0055085 139 0.020
purine ribonucleotide metabolic process GO:0009150 145 0.020
cellular polysaccharide biosynthetic process GO:0033692 7 0.020
carboxylic acid metabolic process GO:0019752 92 0.020
Mouse
regulation of phosphorus metabolic process GO:0051174 210 0.020
regulation of hydrolase activity GO:0051336 97 0.019
transcription from rna polymerase ii promoter GO:0006366 368 0.019
establishment of localization in cell GO:0051649 402 0.019
Mouse
hair cell differentiation GO:0035315 47 0.019
reproductive system development GO:0061458 74 0.019
establishment of nucleus localization GO:0040023 26 0.019
connective tissue development GO:0061448 3 0.019
organonitrogen compound biosynthetic process GO:1901566 117 0.019
cellular response to endogenous stimulus GO:0071495 80 0.019
Mouse
innate immune response GO:0045087 144 0.019
digestive system development GO:0055123 149 0.019
intracellular transport GO:0046907 228 0.018
Mouse
aromatic compound catabolic process GO:0019439 166 0.018
regulation of response to stress GO:0080134 200 0.018
positive regulation of cellular catabolic process GO:0031331 95 0.018
Mouse
programmed cell death GO:0012501 257 0.018
glycolytic process GO:0006096 6 0.018
Mouse
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.018
locomotory behavior GO:0007626 176 0.018
lipid biosynthetic process GO:0008610 46 0.017
regulation of catabolic process GO:0009894 170 0.017
Mouse
cellular protein complex assembly GO:0043623 71 0.017
ribonucleoside triphosphate metabolic process GO:0009199 119 0.017
glycosyl compound biosynthetic process GO:1901659 3 0.017
regulation of developmental growth GO:0048638 174 0.017
regulation of transport GO:0051049 181 0.017
response to nitrogen compound GO:1901698 90 0.017
Mouse
response to endogenous stimulus GO:0009719 119 0.017
Mouse
eye development GO:0001654 323 0.016
regulation of anatomical structure morphogenesis GO:0022603 242 0.016
positive regulation of lipid metabolic process GO:0045834 4 0.016
regulation of phosphorylation GO:0042325 147 0.016
response to organic substance GO:0010033 284 0.016
Mouse
tube morphogenesis GO:0035239 191 0.016
regulation of steroid metabolic process GO:0019218 2 0.016
epithelial cell development GO:0002064 274 0.016
purine containing compound catabolic process GO:0072523 112 0.016
alditol phosphate metabolic process GO:0052646 2 0.015
Mouse
regulation of actin filament depolymerization GO:0030834 3 0.015
nucleoside biosynthetic process GO:0009163 3 0.015
positive regulation of molecular function GO:0044093 136 0.015
muscle cell differentiation GO:0042692 103 0.015
organonitrogen compound catabolic process GO:1901565 128 0.015
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.015
cellular response to organic substance GO:0071310 132 0.015
Mouse
monocarboxylic acid transport GO:0015718 3 0.015
retina development in camera type eye GO:0060041 4 0.015
regulation of nucleotide catabolic process GO:0030811 48 0.014
triglyceride catabolic process GO:0019433 3 0.014
purine ribonucleoside biosynthetic process GO:0046129 3 0.014
flight GO:0060361 10 0.014
alcohol metabolic process GO:0006066 25 0.014
organic hydroxy compound catabolic process GO:1901616 4 0.014
purine ribonucleoside monophosphate catabolic process GO:0009169 38 0.014
death GO:0016265 284 0.014
immune system process GO:0002376 347 0.014
purine ribonucleoside monophosphate biosynthetic process GO:0009168 3 0.014
mitochondrion organization GO:0007005 65 0.014
response to oxygen containing compound GO:1901700 200 0.014
Mouse
cellular protein localization GO:0034613 160 0.014
ameboidal type cell migration GO:0001667 151 0.014
positive regulation of phosphate metabolic process GO:0045937 139 0.014
epithelial cell migration GO:0010631 148 0.014
cellular macromolecule localization GO:0070727 220 0.014
regulation of dna templated transcription in response to stress GO:0043620 4 0.014
positive regulation of macromolecule metabolic process GO:0010604 405 0.014
cell motility GO:0048870 251 0.013
lipid catabolic process GO:0016042 21 0.013
posttranscriptional regulation of gene expression GO:0010608 145 0.013
nicotinamide nucleotide metabolic process GO:0046496 2 0.013
actin filament based movement GO:0030048 26 0.013
multi organism reproductive behavior GO:0044705 121 0.013
nucleotide catabolic process GO:0009166 109 0.013
response to alcohol GO:0097305 95 0.013
response to growth factor GO:0070848 31 0.013
regulation of cellular amine metabolic process GO:0033238 3 0.013
ovulation GO:0030728 4 0.013
nadh metabolic process GO:0006734 1 0.013
purine containing compound biosynthetic process GO:0072522 30 0.013
regulation of cellular component biogenesis GO:0044087 201 0.013
purine nucleoside catabolic process GO:0006152 112 0.013
sperm mitochondrion organization GO:0030382 7 0.012
morphogenesis of a branching epithelium GO:0061138 45 0.012
cellular amine metabolic process GO:0044106 12 0.012
negative regulation of actin filament depolymerization GO:0030835 2 0.012
regulation of system process GO:0044057 36 0.012
regulation of anatomical structure size GO:0090066 163 0.012
cytoskeleton dependent intracellular transport GO:0030705 44 0.012
positive regulation of hydrolase activity GO:0051345 78 0.012
stem cell development GO:0048864 79 0.012
response to abiotic stimulus GO:0009628 341 0.012
macromolecular complex assembly GO:0065003 256 0.012
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.011
regulation of protein transport GO:0051223 57 0.011
negative regulation of developmental process GO:0051093 201 0.011
response to lipopolysaccharide GO:0032496 4 0.011
protein modification process GO:0036211 438 0.011
sex differentiation GO:0007548 81 0.011
regulation of establishment of protein localization GO:0070201 61 0.011
regulation of cell motility GO:2000145 23 0.011
negative regulation of catalytic activity GO:0043086 42 0.011
notch signaling pathway GO:0007219 120 0.011
positive regulation of nucleotide metabolic process GO:0045981 55 0.011
nucleus organization GO:0006997 45 0.011
ion transport GO:0006811 145 0.011
lateral inhibition GO:0046331 206 0.011
regulation of localization GO:0032879 275 0.011
dna integrity checkpoint GO:0031570 81 0.011
tissue migration GO:0090130 155 0.011
purine ribonucleoside catabolic process GO:0046130 112 0.011
synaptic transmission GO:0007268 288 0.011
male mating behavior GO:0060179 70 0.011
nucleoside triphosphate catabolic process GO:0009143 108 0.011
carboxylic acid biosynthetic process GO:0046394 15 0.011
regulation of programmed cell death GO:0043067 152 0.010
purine nucleotide catabolic process GO:0006195 109 0.010
compound eye development GO:0048749 307 0.010
tricarboxylic acid metabolic process GO:0072350 1 0.010
positive regulation of reactive oxygen species metabolic process GO:2000379 0 0.010
reproductive structure development GO:0048608 74 0.010
positive regulation of multicellular organismal process GO:0051240 143 0.010
epithelium migration GO:0090132 148 0.010
positive regulation of phosphorus metabolic process GO:0010562 139 0.010
nucleotide metabolic process GO:0009117 161 0.010
organic anion transport GO:0015711 28 0.010
mapk cascade GO:0000165 107 0.010
neutral lipid metabolic process GO:0006638 12 0.010
phenol containing compound metabolic process GO:0018958 57 0.010
intracellular signal transduction GO:0035556 300 0.010

Gpdh disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.140
glucose metabolism disease DOID:4194 0 0.140
acquired metabolic disease DOID:0060158 0 0.140
carbohydrate metabolism disease DOID:0050013 0 0.140
disease of anatomical entity DOID:7 0 0.025
musculoskeletal system disease DOID:17 0 0.015
cardiovascular system disease DOID:1287 0 0.015
heart disease DOID:114 0 0.015
myopathy DOID:423 0 0.015
cardiomyopathy DOID:0050700 0 0.015
dilated cardiomyopathy DOID:12930 0 0.015
muscle tissue disease DOID:66 0 0.015
muscular disease DOID:0080000 0 0.015
intrinsic cardiomyopathy DOID:0060036 0 0.015
primary hypertrophic osteoarthropathy DOID:14283 0 0.014
syndrome DOID:225 0 0.014
nervous system disease DOID:863 0 0.012
central nervous system disease DOID:331 0 0.012
inherited metabolic disorder DOID:655 0 0.012
neurodegenerative disease DOID:1289 0 0.010