Drosophila melanogaster

4 known processes

LysC (Dmel_CG9111)

Lysozyme C

(Aliases: Lys C,Dmel\CG9111,CG9111,lysC)

LysC biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
tissue death GO:0016271 102 0.263
response to external biotic stimulus GO:0043207 293 0.261
single fertilization GO:0007338 24 0.252
immune response GO:0006955 246 0.236
defense response to gram positive bacterium GO:0050830 41 0.223
histolysis GO:0007559 102 0.207
salivary gland development GO:0007431 162 0.207
innate immune response GO:0045087 144 0.204
salivary gland morphogenesis GO:0007435 145 0.199
exocrine system development GO:0035272 162 0.198
developmental programmed cell death GO:0010623 138 0.195
defense response GO:0006952 300 0.187
defense response to gram negative bacterium GO:0050829 94 0.178
fertilization GO:0009566 26 0.168
gland morphogenesis GO:0022612 145 0.164
regulation of defense response GO:0031347 102 0.163
response to bacterium GO:0009617 198 0.154
salivary gland cell autophagic cell death GO:0035071 83 0.142
negative regulation of immune system process GO:0002683 50 0.140
anatomical structure homeostasis GO:0060249 97 0.138
gland development GO:0048732 191 0.132
negative regulation of response to stimulus GO:0048585 258 0.127
autophagic cell death GO:0048102 83 0.126
defense response to other organism GO:0098542 225 0.119
immune system process GO:0002376 347 0.110
response to other organism GO:0051707 293 0.110
salivary gland histolysis GO:0035070 88 0.107
death GO:0016265 284 0.106
homeostatic process GO:0042592 199 0.105
defense response to bacterium GO:0042742 178 0.103
programmed cell death GO:0012501 257 0.100
regulation of response to stress GO:0080134 200 0.096
cell death GO:0008219 279 0.095
cell recognition GO:0008037 102 0.087
regulation of immune system process GO:0002682 176 0.084
tissue homeostasis GO:0001894 36 0.080
negative regulation of defense response GO:0031348 35 0.079
regulation of innate immune response GO:0045088 71 0.074
response to biotic stimulus GO:0009607 294 0.070
regulation of immune response GO:0050776 118 0.068
multicellular organismal homeostasis GO:0048871 41 0.056
appendage development GO:0048736 401 0.050
appendage morphogenesis GO:0035107 397 0.049
negative regulation of immune response GO:0050777 39 0.049
imaginal disc derived appendage development GO:0048737 399 0.048
imaginal disc derived wing morphogenesis GO:0007476 337 0.048
wing disc morphogenesis GO:0007472 344 0.047
response to temperature stimulus GO:0009266 106 0.046
catabolic process GO:0009056 409 0.045
retina homeostasis GO:0001895 13 0.043
phosphatidylethanolamine metabolic process GO:0046337 1 0.041
small molecule metabolic process GO:0044281 305 0.040
organonitrogen compound metabolic process GO:1901564 318 0.040
negative regulation of innate immune response GO:0045824 30 0.039
imaginal disc derived appendage morphogenesis GO:0035114 395 0.039
cellular catabolic process GO:0044248 372 0.036
organic substance catabolic process GO:1901575 308 0.034
anion homeostasis GO:0055081 3 0.033
cellular amino acid metabolic process GO:0006520 61 0.033
post embryonic appendage morphogenesis GO:0035120 385 0.032
positive regulation of response to stimulus GO:0048584 323 0.031
ethanolamine containing compound metabolic process GO:0042439 4 0.031
regulation of multicellular organismal development GO:2000026 414 0.029
developmental growth GO:0048589 280 0.029
protein modification process GO:0036211 438 0.029
macromolecular complex assembly GO:0065003 256 0.028
negative regulation of cellular metabolic process GO:0031324 382 0.027
regulation of localization GO:0032879 275 0.027
cellular amine metabolic process GO:0044106 12 0.026
amine metabolic process GO:0009308 12 0.026
carbohydrate derivative metabolic process GO:1901135 217 0.025
vesicle mediated transport GO:0016192 381 0.024
phospholipid homeostasis GO:0055091 1 0.023
single organism catabolic process GO:0044712 228 0.023
phosphorylation GO:0016310 294 0.022
triglyceride catabolic process GO:0019433 3 0.022
neutral lipid biosynthetic process GO:0046460 2 0.022
negative regulation of gene expression GO:0010629 387 0.022
cellular protein modification process GO:0006464 438 0.022
carboxylic acid metabolic process GO:0019752 92 0.022
morphogenesis of a polarized epithelium GO:0001738 93 0.021
organophosphate catabolic process GO:0046434 112 0.021
negative regulation of signaling GO:0023057 219 0.021
body morphogenesis GO:0010171 2 0.021
cholesterol transport GO:0030301 2 0.021
intracellular signal transduction GO:0035556 300 0.021
acylglycerol biosynthetic process GO:0046463 2 0.021
phosphatidic acid metabolic process GO:0046473 1 0.020
organophosphate metabolic process GO:0019637 195 0.020
positive regulation of cell communication GO:0010647 250 0.020
positive regulation of signaling GO:0023056 243 0.020
regulation of transport GO:0051049 181 0.019
positive regulation of biosynthetic process GO:0009891 316 0.019
response to organic substance GO:0010033 284 0.019
forebrain development GO:0030900 2 0.019
epithelial cell differentiation GO:0030855 322 0.019
organic substance transport GO:0071702 257 0.019
cellular response to chemical stimulus GO:0070887 199 0.018
regulation of phosphorus metabolic process GO:0051174 210 0.018
columnar cuboidal epithelial cell development GO:0002066 249 0.018
negative regulation of signal transduction GO:0009968 206 0.018
oxoacid metabolic process GO:0043436 103 0.018
protein complex biogenesis GO:0070271 201 0.018
cellular amide metabolic process GO:0043603 80 0.017
sterol homeostasis GO:0055092 4 0.017
regulation of cell cycle GO:0051726 291 0.017
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.017
epithelial cell development GO:0002064 274 0.017
growth GO:0040007 359 0.017
organic acid metabolic process GO:0006082 103 0.016
morphogenesis of an epithelium GO:0002009 276 0.016
protein localization GO:0008104 284 0.016
positive regulation of multicellular organismal process GO:0051240 143 0.016
regulation of phosphate metabolic process GO:0019220 210 0.016
regulation of cholesterol transport GO:0032374 1 0.016
organonitrogen compound catabolic process GO:1901565 128 0.016
regionalization GO:0003002 416 0.016
cell proliferation GO:0008283 299 0.016
peptide metabolic process GO:0006518 80 0.016
regulation of cell differentiation GO:0045595 302 0.016
cellular modified amino acid metabolic process GO:0006575 45 0.015
establishment of localization in cell GO:0051649 402 0.015
ovarian follicle cell development GO:0030707 248 0.015
glycerolipid catabolic process GO:0046503 3 0.015
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.015
neutral lipid catabolic process GO:0046461 3 0.015
regulation of protein metabolic process GO:0051246 256 0.015
regulation of cellular protein metabolic process GO:0032268 243 0.015
protein complex assembly GO:0006461 200 0.015
regulation of intracellular signal transduction GO:1902531 236 0.015
response to oxygen containing compound GO:1901700 200 0.015
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.014
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.014
cellular response to organic substance GO:0071310 132 0.014
eggshell formation GO:0030703 105 0.014
cellular macromolecule localization GO:0070727 220 0.014
response to lipopolysaccharide GO:0032496 4 0.014
triglyceride biosynthetic process GO:0019432 2 0.014
proteolysis GO:0006508 192 0.014
regulation of phosphorylation GO:0042325 147 0.014
organonitrogen compound biosynthetic process GO:1901566 117 0.014
protein phosphorylation GO:0006468 169 0.013
organic hydroxy compound metabolic process GO:1901615 83 0.013
cellular component assembly involved in morphogenesis GO:0010927 151 0.013
alditol phosphate metabolic process GO:0052646 2 0.013
mitotic nuclear division GO:0007067 213 0.013
intracellular transport GO:0046907 228 0.013
endocytosis GO:0006897 310 0.013
segmentation GO:0035282 207 0.013
regulation of sterol transport GO:0032371 1 0.013
regulation of cellular amine metabolic process GO:0033238 3 0.013
macromolecule catabolic process GO:0009057 161 0.013
positive regulation of sequestering of triglyceride GO:0010890 1 0.013
phosphatidylcholine metabolic process GO:0046470 3 0.013
carbohydrate derivative biosynthetic process GO:1901137 85 0.013
cell division GO:0051301 248 0.013
phagocytosis GO:0006909 215 0.013
single organism biosynthetic process GO:0044711 206 0.013
response to copper ion GO:0046688 4 0.013
positive regulation of lipid storage GO:0010884 4 0.013
response to extracellular stimulus GO:0009991 116 0.013
response to acid chemical GO:0001101 25 0.013
tissue morphogenesis GO:0048729 297 0.012
cellular response to dna damage stimulus GO:0006974 223 0.012
response to nutrient levels GO:0031667 114 0.012
rna processing GO:0006396 147 0.012
negative regulation of biosynthetic process GO:0009890 277 0.012
regulation of cellular ketone metabolic process GO:0010565 3 0.012
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.012
regulation of cell death GO:0010941 173 0.012
glycoprotein biosynthetic process GO:0009101 41 0.012
regulation of anatomical structure morphogenesis GO:0022603 242 0.012
regulation of catabolic process GO:0009894 170 0.012
negative regulation of cell communication GO:0010648 223 0.012
negative regulation of cell differentiation GO:0045596 143 0.012
single organism intracellular transport GO:1902582 207 0.012
regulation of molecular function GO:0065009 217 0.011
nucleobase containing small molecule metabolic process GO:0055086 174 0.011
rhythmic process GO:0048511 106 0.011
regulation of growth GO:0040008 233 0.011
cellular macromolecule catabolic process GO:0044265 136 0.011
regulation of organelle organization GO:0033043 196 0.011
cell growth GO:0016049 108 0.011
notch signaling pathway GO:0007219 120 0.011
negative regulation of nucleic acid templated transcription GO:1903507 240 0.011
regulation of cell development GO:0060284 215 0.011
negative regulation of cellular protein metabolic process GO:0032269 85 0.011
compound eye development GO:0048749 307 0.011
humoral immune response GO:0006959 117 0.011
nucleoside phosphate metabolic process GO:0006753 162 0.011
cellular response to biotic stimulus GO:0071216 4 0.011
regulation of cellular amino acid metabolic process GO:0006521 0 0.011
regulation of developmental growth GO:0048638 174 0.010
molting cycle chitin based cuticle GO:0007591 56 0.010
gene silencing GO:0016458 138 0.010
maintenance of location GO:0051235 73 0.010
negative regulation of developmental process GO:0051093 201 0.010
negative regulation of multicellular organismal process GO:0051241 142 0.010
regulation of catalytic activity GO:0050790 185 0.010
immune response activating signal transduction GO:0002757 2 0.010

LysC disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.960
amyloidosis DOID:9120 0 0.960
acquired metabolic disease DOID:0060158 0 0.960
familial visceral amyloidosis DOID:0050636 0 0.960
disease of anatomical entity DOID:7 0 0.039
familial hyperlipidemia DOID:1168 0 0.034
lipid metabolism disorder DOID:3146 0 0.034
familial combined hyperlipidemia DOID:13809 0 0.034
inherited metabolic disorder DOID:655 0 0.034
hair disease DOID:421 0 0.023
integumentary system disease DOID:16 0 0.023
hypotrichosis DOID:4535 0 0.023
diabetes mellitus DOID:9351 0 0.018
carbohydrate metabolism disease DOID:0050013 0 0.018
glucose metabolism disease DOID:4194 0 0.018
familial lipoprotein lipase deficiency DOID:14118 0 0.018
type 2 diabetes mellitus DOID:9352 0 0.016