Drosophila melanogaster

40 known processes

mtm (Dmel_CG9115)

myotubularin

(Aliases: CG9115,MTM1,dMTMH1,Dmel\CG9115)

mtm biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
lipid modification GO:0030258 24 0.425
Mouse Worm
positive regulation of signaling GO:0023056 243 0.342
regulation of cellular protein metabolic process GO:0032268 243 0.220
establishment of localization in cell GO:0051649 402 0.169
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.168
hemocyte differentiation GO:0042386 38 0.144
phosphorylation GO:0016310 294 0.136
taxis GO:0042330 304 0.131
single organism intracellular transport GO:1902582 207 0.126
positive regulation of response to stimulus GO:0048584 323 0.118
epithelial cell development GO:0002064 274 0.104
cellular response to extracellular stimulus GO:0031668 64 0.099
organic substance transport GO:0071702 257 0.097
positive regulation of signal transduction GO:0009967 223 0.095
regulation of response to stress GO:0080134 200 0.094
epithelial cell differentiation GO:0030855 322 0.093
secretion by cell GO:0032940 101 0.090
lipid metabolic process GO:0006629 121 0.088
Mouse Worm
immune system process GO:0002376 347 0.086
eye morphogenesis GO:0048592 260 0.085
eye development GO:0001654 323 0.084
regulation of apoptotic process GO:0042981 130 0.080
single organism behavior GO:0044708 391 0.078
sensory organ morphogenesis GO:0090596 260 0.068
positive regulation of rna biosynthetic process GO:1902680 266 0.067
cell division GO:0051301 248 0.064
response to oxygen containing compound GO:1901700 200 0.064
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.063
vesicle mediated transport GO:0016192 381 0.062
tissue morphogenesis GO:0048729 297 0.061
protein modification process GO:0036211 438 0.060
immune response GO:0006955 246 0.058
developmental maturation GO:0021700 172 0.057
positive regulation of cell communication GO:0010647 250 0.056
cell proliferation GO:0008283 299 0.056
positive regulation of phosphorus metabolic process GO:0010562 139 0.054
positive regulation of molecular function GO:0044093 136 0.053
spermatogenesis GO:0007283 200 0.053
regulation of localization GO:0032879 275 0.053
Rat Worm
regulation of cell development GO:0060284 215 0.053
secretion GO:0046903 109 0.053
male gamete generation GO:0048232 201 0.051
locomotory behavior GO:0007626 176 0.051
Zebrafish
ovarian follicle cell development GO:0030707 248 0.049
endocytosis GO:0006897 310 0.049
Rat Worm
cytoplasmic transport GO:0016482 130 0.048
Rat
regulation of transport GO:0051049 181 0.047
Rat Worm
regulation of intracellular signal transduction GO:1902531 236 0.045
intracellular signal transduction GO:0035556 300 0.045
gtp catabolic process GO:0006184 72 0.045
phagocytosis GO:0006909 215 0.044
Worm
protein secretion GO:0009306 45 0.044
defense response to other organism GO:0098542 225 0.043
regulation of transferase activity GO:0051338 58 0.043
intracellular transport GO:0046907 228 0.043
positive regulation of biosynthetic process GO:0009891 316 0.043
regulation of molecular function GO:0065009 217 0.043
cellular lipid metabolic process GO:0044255 83 0.042
Mouse Worm
regulation of catalytic activity GO:0050790 185 0.042
cellular response to external stimulus GO:0071496 66 0.041
positive regulation of protein metabolic process GO:0051247 128 0.040
translation GO:0006412 69 0.040
compound eye morphogenesis GO:0001745 249 0.040
neuron projection guidance GO:0097485 241 0.040
cortical cytoskeleton organization GO:0030865 29 0.039
response to external biotic stimulus GO:0043207 293 0.038
cortical actin cytoskeleton organization GO:0030866 24 0.038
catabolic process GO:0009056 409 0.038
Zebrafish Mouse Rat
axon development GO:0061564 297 0.037
chemotaxis GO:0006935 249 0.037
regulation of mapk cascade GO:0043408 92 0.037
axonogenesis GO:0007409 290 0.037
regulation of cell morphogenesis GO:0022604 163 0.036
regulation of anatomical structure morphogenesis GO:0022603 242 0.035
regulation of notch signaling pathway GO:0008593 100 0.035
regulation of phosphate metabolic process GO:0019220 210 0.035
positive regulation of phosphate metabolic process GO:0045937 139 0.034
regulation of protein metabolic process GO:0051246 256 0.034
positive regulation of intracellular signal transduction GO:1902533 116 0.034
signal transduction by phosphorylation GO:0023014 107 0.034
cellular catabolic process GO:0044248 372 0.033
Zebrafish Rat
embryo development ending in birth or egg hatching GO:0009792 152 0.032
Zebrafish
regulation of cell differentiation GO:0045595 302 0.032
nucleoside catabolic process GO:0009164 112 0.032
response to biotic stimulus GO:0009607 294 0.032
defense response to bacterium GO:0042742 178 0.030
positive regulation of kinase activity GO:0033674 25 0.030
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.030
transcription from rna polymerase ii promoter GO:0006366 368 0.030
negative regulation of apoptotic process GO:0043066 63 0.030
positive regulation of cellular protein metabolic process GO:0032270 118 0.029
positive regulation of protein kinase activity GO:0045860 25 0.029
regulation of cellular localization GO:0060341 136 0.029
Rat
cellular response to starvation GO:0009267 61 0.029
innate immune response GO:0045087 144 0.028
negative regulation of signaling GO:0023057 219 0.028
positive regulation of gene expression GO:0010628 290 0.028
posttranscriptional regulation of gene expression GO:0010608 145 0.028
cellular homeostasis GO:0019725 80 0.028
Zebrafish Mouse
small molecule metabolic process GO:0044281 305 0.027
Mouse
cell cell signaling involved in cell fate commitment GO:0045168 210 0.027
phenol containing compound metabolic process GO:0018958 57 0.026
photoreceptor cell differentiation GO:0046530 170 0.026
regulation of kinase activity GO:0043549 53 0.026
purine ribonucleoside catabolic process GO:0046130 112 0.026
cytoplasmic transport nurse cell to oocyte GO:0007303 12 0.026
localization of cell GO:0051674 257 0.026
Worm
columnar cuboidal epithelial cell development GO:0002066 249 0.026
protein localization GO:0008104 284 0.025
organelle fission GO:0048285 340 0.025
mapk cascade GO:0000165 107 0.025
dendrite morphogenesis GO:0048813 199 0.024
autophagic vacuole assembly GO:0000045 2 0.024
nuclear division GO:0000280 332 0.024
positive regulation of catalytic activity GO:0043085 118 0.024
feeding behavior GO:0007631 50 0.024
aromatic compound catabolic process GO:0019439 166 0.024
defense response GO:0006952 300 0.024
regulation of phosphorus metabolic process GO:0051174 210 0.024
rhabdomere development GO:0042052 38 0.024
regulation of secretion by cell GO:1903530 39 0.023
ribonucleoside metabolic process GO:0009119 127 0.023
response to other organism GO:0051707 293 0.023
blastoderm segmentation GO:0007350 159 0.023
synaptic transmission GO:0007268 288 0.023
Rat
ribose phosphate metabolic process GO:0019693 145 0.023
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.022
nucleoside triphosphate metabolic process GO:0009141 120 0.022
cellular response to nutrient levels GO:0031669 62 0.022
nucleoside metabolic process GO:0009116 127 0.022
wing disc morphogenesis GO:0007472 344 0.022
signal release GO:0023061 49 0.022
establishment of protein localization GO:0045184 163 0.022
positive regulation of phosphorylation GO:0042327 87 0.022
purine ribonucleoside metabolic process GO:0046128 127 0.021
cell migration GO:0016477 238 0.021
Worm
positive regulation of cellular component organization GO:0051130 156 0.021
regulation of protein transport GO:0051223 57 0.021
trachea development GO:0060438 29 0.021
membrane invagination GO:0010324 11 0.021
Worm
positive regulation of mapk cascade GO:0043410 63 0.021
regulation of programmed cell death GO:0043067 152 0.021
glycosyl compound catabolic process GO:1901658 112 0.021
regulation of cell death GO:0010941 173 0.021
cellular ion homeostasis GO:0006873 39 0.021
protein transport GO:0015031 155 0.021
cellular protein modification process GO:0006464 438 0.021
regulation of protein phosphorylation GO:0001932 64 0.020
regulation of multicellular organismal development GO:2000026 414 0.020
Mouse
response to bacterium GO:0009617 198 0.020
regulation of phosphorylation GO:0042325 147 0.020
microtubule based transport GO:0010970 42 0.020
regulation of translation GO:0006417 56 0.019
protein phosphorylation GO:0006468 169 0.019
dendrite development GO:0016358 204 0.019
regulation of neuron differentiation GO:0045664 103 0.019
cell projection assembly GO:0030031 94 0.019
positive regulation of transferase activity GO:0051347 26 0.019
chemical homeostasis GO:0048878 92 0.019
embryonic morphogenesis GO:0048598 206 0.018
cellular response to chemical stimulus GO:0070887 199 0.018
defense response to gram negative bacterium GO:0050829 94 0.018
ovarian follicle cell migration GO:0007297 121 0.018
nitrogen compound transport GO:0071705 85 0.018
axon guidance GO:0007411 233 0.018
gtp metabolic process GO:0046039 72 0.018
vesicle localization GO:0051648 55 0.018
regulation of cell proliferation GO:0042127 163 0.018
negative regulation of programmed cell death GO:0043069 72 0.017
negative regulation of gene expression GO:0010629 387 0.017
regulation of nervous system development GO:0051960 248 0.017
Mouse
autophagy GO:0006914 108 0.017
Zebrafish
purine nucleoside metabolic process GO:0042278 127 0.017
purine containing compound catabolic process GO:0072523 112 0.017
gland development GO:0048732 191 0.017
programmed cell death GO:0012501 257 0.017
response to hexose GO:0009746 3 0.017
membrane organization GO:0061024 112 0.017
Worm
lipid biosynthetic process GO:0008610 46 0.017
regulation of membrane potential GO:0042391 35 0.017
Rat
organic substance catabolic process GO:1901575 308 0.016
Mouse Rat
carbohydrate derivative catabolic process GO:1901136 118 0.016
organophosphate metabolic process GO:0019637 195 0.016
Mouse
positive regulation of rna metabolic process GO:0051254 271 0.016
negative regulation of biosynthetic process GO:0009890 277 0.016
lateral inhibition GO:0046331 206 0.016
positive regulation of protein modification process GO:0031401 58 0.016
single organism biosynthetic process GO:0044711 206 0.016
regulation of developmental growth GO:0048638 174 0.016
cuticle pigmentation GO:0048067 22 0.016
nucleobase containing small molecule metabolic process GO:0055086 174 0.016
purine containing compound metabolic process GO:0072521 155 0.016
cellular protein localization GO:0034613 160 0.015
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.015
regulation of gtp catabolic process GO:0033124 44 0.015
glycosyl compound metabolic process GO:1901657 127 0.015
digestive tract development GO:0048565 149 0.015
positive regulation of multicellular organismal process GO:0051240 143 0.015
compound eye development GO:0048749 307 0.015
regulation of cellular component biogenesis GO:0044087 201 0.015
digestive system development GO:0055123 149 0.015
positive regulation of transcription dna templated GO:0045893 266 0.015
stem cell differentiation GO:0048863 117 0.015
organic acid metabolic process GO:0006082 103 0.015
regulation of cell size GO:0008361 63 0.014
proteolysis GO:0006508 192 0.014
positive regulation of cellular biosynthetic process GO:0031328 316 0.014
response to monosaccharide GO:0034284 4 0.014
negative regulation of cell differentiation GO:0045596 143 0.014
regulation of anatomical structure size GO:0090066 163 0.014
guanosine containing compound catabolic process GO:1901069 74 0.014
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.014
hematopoietic or lymphoid organ development GO:0048534 57 0.014
regulation of establishment of protein localization GO:0070201 61 0.014
regulation of cellular component size GO:0032535 98 0.014
developmental growth GO:0048589 280 0.014
cell maturation GO:0048469 144 0.013
single organism catabolic process GO:0044712 228 0.013
Mouse
regulation of protein localization GO:0032880 76 0.013
purine nucleoside triphosphate catabolic process GO:0009146 108 0.013
negative regulation of response to stimulus GO:0048585 258 0.013
rhythmic behavior GO:0007622 76 0.013
cellular chemical homeostasis GO:0055082 40 0.013
ribonucleoside triphosphate catabolic process GO:0009203 108 0.012
regulation of protein modification process GO:0031399 112 0.012
purine ribonucleotide metabolic process GO:0009150 145 0.012
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.012
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.012
apoptotic process GO:0006915 159 0.012
single organism membrane organization GO:0044802 93 0.012
regulation of intracellular transport GO:0032386 64 0.012
Rat
positive regulation of apoptotic process GO:0043065 47 0.012
purine nucleoside catabolic process GO:0006152 112 0.012
response to nutrient levels GO:0031667 114 0.012
response to extracellular stimulus GO:0009991 116 0.012
central nervous system development GO:0007417 201 0.012
cellular response to organic substance GO:0071310 132 0.012
regulation of immune response GO:0050776 118 0.011
biological adhesion GO:0022610 138 0.011
multicellular organismal reproductive behavior GO:0033057 110 0.011
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.011
positive regulation of macromolecule metabolic process GO:0010604 405 0.011
regulation of cell projection organization GO:0031344 92 0.011
cell motility GO:0048870 251 0.011
Worm
regulation of response to external stimulus GO:0032101 115 0.011
larval development GO:0002164 104 0.011
regulation of organelle organization GO:0033043 196 0.011
embryonic development via the syncytial blastoderm GO:0001700 148 0.011
cellular response to oxygen containing compound GO:1901701 79 0.011
adult locomotory behavior GO:0008344 76 0.011
salivary gland morphogenesis GO:0007435 145 0.011
cellular response to decreased oxygen levels GO:0036294 30 0.011
regulation of hydrolase activity GO:0051336 97 0.011
actin filament based process GO:0030029 220 0.011
organonitrogen compound metabolic process GO:1901564 318 0.011
notch signaling pathway GO:0007219 120 0.010
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.010
endomembrane system organization GO:0010256 119 0.010
wound healing GO:0042060 75 0.010
response to lipopolysaccharide GO:0032496 4 0.010
lipid homeostasis GO:0055088 33 0.010
regulation of protein secretion GO:0050708 13 0.010
compound eye photoreceptor cell differentiation GO:0001751 140 0.010
epithelial cell migration GO:0010631 148 0.010
stress activated protein kinase signaling cascade GO:0031098 55 0.010
oocyte dorsal ventral axis specification GO:0007310 34 0.010
regulation of immune system process GO:0002682 176 0.010

mtm disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.011