Drosophila melanogaster

21 known processes

Ptp61F (Dmel_CG9181)

Protein tyrosine phosphatase 61F

(Aliases: PTP61F,dptp61F,DPTP61F,anon-WO0140519.98,CG9178,dPTP61F,CG9181,anon-WO0118547.297,ptp61F,Dmel\CG9181,BEST:LP01280,R-PTP 61F)

Ptp61F biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cell proliferation GO:0008283 299 0.382
regulation of cell death GO:0010941 173 0.353
positive regulation of macromolecule metabolic process GO:0010604 405 0.331
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.314
neuron projection guidance GO:0097485 241 0.299
negative regulation of rna metabolic process GO:0051253 251 0.293
positive regulation of nucleic acid templated transcription GO:1903508 266 0.291
transcription from rna polymerase ii promoter GO:0006366 368 0.290
growth GO:0040007 359 0.290
death GO:0016265 284 0.282
response to nutrient levels GO:0031667 114 0.274
programmed cell death GO:0012501 257 0.267
cellular response to nutrient levels GO:0031669 62 0.246
regulation of growth GO:0040008 233 0.204
meiotic cell cycle process GO:1903046 132 0.203
positive regulation of cellular protein metabolic process GO:0032270 118 0.189
male gamete generation GO:0048232 201 0.184
axon guidance GO:0007411 233 0.183
positive regulation of rna metabolic process GO:0051254 271 0.178
cellular catabolic process GO:0044248 372 0.169
spermatogenesis GO:0007283 200 0.168
negative regulation of cellular metabolic process GO:0031324 382 0.166
positive regulation of protein metabolic process GO:0051247 128 0.163
multicellular organism growth GO:0035264 46 0.156
posttranscriptional regulation of gene expression GO:0010608 145 0.156
regulation of response to stress GO:0080134 200 0.154
negative regulation of gene expression GO:0010629 387 0.154
response to extracellular stimulus GO:0009991 116 0.146
positive regulation of rna biosynthetic process GO:1902680 266 0.146
regulation of developmental growth GO:0048638 174 0.143
negative regulation of signaling GO:0023057 219 0.135
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.133
dna metabolic process GO:0006259 227 0.125
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 11 0.121
phosphorylation GO:0016310 294 0.121
cellular response to extracellular stimulus GO:0031668 64 0.119
negative regulation of erbb signaling pathway GO:1901185 29 0.116
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.113
response to biotic stimulus GO:0009607 294 0.112
developmental growth GO:0048589 280 0.112
taxis GO:0042330 304 0.110
regulation of protein metabolic process GO:0051246 256 0.110
positive regulation of transcription dna templated GO:0045893 266 0.107
negative regulation of signal transduction GO:0009968 206 0.105
cell death GO:0008219 279 0.105
protein modification process GO:0036211 438 0.105
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress GO:0070059 4 0.103
chemotaxis GO:0006935 249 0.103
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.102
intrinsic apoptotic signaling pathway GO:0097193 16 0.094
cell growth GO:0016049 108 0.092
apoptotic process GO:0006915 159 0.091
lipid metabolic process GO:0006629 121 0.091
regulation of apoptotic process GO:0042981 130 0.091
proteolysis GO:0006508 192 0.091
organelle fission GO:0048285 340 0.090
mitotic spindle organization GO:0007052 220 0.090
mitotic nuclear division GO:0007067 213 0.087
translation GO:0006412 69 0.083
negative regulation of cell communication GO:0010648 223 0.082
regulation of translation GO:0006417 56 0.082
negative regulation of nucleic acid templated transcription GO:1903507 240 0.079
gland development GO:0048732 191 0.079
oxidation reduction process GO:0055114 123 0.077
positive regulation of cellular biosynthetic process GO:0031328 316 0.077
stress activated mapk cascade GO:0051403 52 0.075
oxoacid metabolic process GO:0043436 103 0.075
regulation of cell differentiation GO:0045595 302 0.075
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.074
regulation of phosphorylation GO:0042325 147 0.073
regulation of intracellular signal transduction GO:1902531 236 0.073
cellular response to external stimulus GO:0071496 66 0.073
dorsal closure GO:0007391 79 0.073
forebrain development GO:0030900 2 0.072
regulation of erbb signaling pathway GO:1901184 42 0.071
aging GO:0007568 143 0.070
nuclear division GO:0000280 332 0.069
mitotic cell cycle phase transition GO:0044772 138 0.069
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.068
negative regulation of cell death GO:0060548 81 0.068
multi organism behavior GO:0051705 175 0.068
response to organic substance GO:0010033 284 0.066
negative regulation of transcription dna templated GO:0045892 237 0.065
positive regulation of cell communication GO:0010647 250 0.064
tube morphogenesis GO:0035239 191 0.064
determination of adult lifespan GO:0008340 137 0.064
positive regulation of developmental process GO:0051094 143 0.064
endocytosis GO:0006897 310 0.063
rna localization GO:0006403 115 0.062
protein catabolic process GO:0030163 101 0.061
regulation of stress activated mapk cascade GO:0032872 41 0.060
regulation of cellular response to stress GO:0080135 89 0.059
morphogenesis of embryonic epithelium GO:0016331 94 0.059
positive regulation of signaling GO:0023056 243 0.059
regulation of cellular component biogenesis GO:0044087 201 0.058
positive regulation of growth GO:0045927 75 0.057
regulation of cell cycle phase transition GO:1901987 130 0.057
regulation of gene expression epigenetic GO:0040029 128 0.057
spindle organization GO:0007051 253 0.057
exocrine system development GO:0035272 162 0.057
cellular response to starvation GO:0009267 61 0.056
protein phosphorylation GO:0006468 169 0.055
response to starvation GO:0042594 97 0.054
positive regulation of biosynthetic process GO:0009891 316 0.054
regulation of cellular protein metabolic process GO:0032268 243 0.053
autophagy GO:0006914 108 0.052
negative regulation of developmental process GO:0051093 201 0.052
negative regulation of synaptic growth at neuromuscular junction GO:0045886 39 0.052
positive regulation of response to stimulus GO:0048584 323 0.052
negative regulation of programmed cell death GO:0043069 72 0.051
positive regulation of developmental growth GO:0048639 62 0.050
negative regulation of growth GO:0045926 84 0.050
neuroblast proliferation GO:0007405 74 0.050
regulation of proteolysis GO:0030162 87 0.050
lateral inhibition GO:0046331 206 0.050
defense response GO:0006952 300 0.049
cellular protein modification process GO:0006464 438 0.049
catabolic process GO:0009056 409 0.048
tissue death GO:0016271 102 0.046
protein ubiquitination GO:0016567 70 0.046
macroautophagy GO:0016236 42 0.046
protein modification by small protein conjugation or removal GO:0070647 106 0.045
negative regulation of multicellular organismal process GO:0051241 142 0.045
spermatid development GO:0007286 98 0.045
mitotic sister chromatid segregation GO:0000070 87 0.044
multicellular organismal aging GO:0010259 140 0.044
energy derivation by oxidation of organic compounds GO:0015980 32 0.044
positive regulation of gene expression GO:0010628 290 0.042
positive regulation of protein modification process GO:0031401 58 0.042
chromosome segregation GO:0007059 157 0.041
regulation of neuroblast proliferation GO:1902692 34 0.041
negative regulation of cell differentiation GO:0045596 143 0.041
reproductive behavior GO:0019098 122 0.041
axonogenesis GO:0007409 290 0.041
chromosome organization GO:0051276 360 0.041
negative regulation of biosynthetic process GO:0009890 277 0.040
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.040
response to oxygen containing compound GO:1901700 200 0.040
compound eye development GO:0048749 307 0.039
positive regulation of wnt signaling pathway GO:0030177 25 0.038
eye morphogenesis GO:0048592 260 0.037
single organism carbohydrate metabolic process GO:0044723 72 0.037
cellular protein catabolic process GO:0044257 83 0.037
regulation of programmed cell death GO:0043067 152 0.037
cilium organization GO:0044782 41 0.036
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.035
response to external biotic stimulus GO:0043207 293 0.035
immune system process GO:0002376 347 0.035
response to heat GO:0009408 63 0.035
embryonic development via the syncytial blastoderm GO:0001700 148 0.035
covalent chromatin modification GO:0016569 106 0.034
positive regulation of cell growth GO:0030307 19 0.034
gene silencing GO:0016458 138 0.034
positive regulation of molecular function GO:0044093 136 0.033
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.033
protein complex biogenesis GO:0070271 201 0.033
regulation of cell cycle process GO:0010564 181 0.033
regulation of nervous system development GO:0051960 248 0.032
nuclear transport GO:0051169 72 0.032
response to abiotic stimulus GO:0009628 341 0.032
regulation of synapse assembly GO:0051963 94 0.032
response to endoplasmic reticulum stress GO:0034976 28 0.032
negative regulation of apoptotic process GO:0043066 63 0.032
columnar cuboidal epithelial cell development GO:0002066 249 0.031
erbb signaling pathway GO:0038127 58 0.031
regulation of mitotic cell cycle GO:0007346 190 0.031
regulation of cell cycle GO:0051726 291 0.031
positive regulation of cellular protein catabolic process GO:1903364 24 0.031
epithelial cell development GO:0002064 274 0.030
cell cell signaling involved in cell fate commitment GO:0045168 210 0.030
regulation of phosphate metabolic process GO:0019220 210 0.030
protein complex assembly GO:0006461 200 0.030
neural precursor cell proliferation GO:0061351 75 0.030
imaginal disc derived wing morphogenesis GO:0007476 337 0.030
cellular amino acid metabolic process GO:0006520 61 0.030
regulation of phosphorus metabolic process GO:0051174 210 0.030
gland morphogenesis GO:0022612 145 0.030
rna processing GO:0006396 147 0.030
asymmetric stem cell division GO:0098722 49 0.030
single organism catabolic process GO:0044712 228 0.030
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.029
wnt signaling pathway GO:0016055 98 0.029
regulation of cell proliferation GO:0042127 163 0.029
gene silencing by mirna GO:0035195 22 0.029
jnk cascade GO:0007254 50 0.029
modification dependent macromolecule catabolic process GO:0043632 79 0.028
regulation of synapse organization GO:0050807 110 0.028
regulation of cell growth GO:0001558 43 0.028
negative regulation of rna biosynthetic process GO:1902679 240 0.028
reproductive system development GO:0061458 74 0.028
notch signaling pathway GO:0007219 120 0.027
appendage morphogenesis GO:0035107 397 0.027
regulation of multicellular organism growth GO:0040014 40 0.027
spermatid differentiation GO:0048515 114 0.027
vesicle mediated transport GO:0016192 381 0.027
regulation of mitotic cell cycle phase transition GO:1901990 130 0.027
intracellular signal transduction GO:0035556 300 0.027
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.027
epidermal growth factor receptor signaling pathway GO:0007173 58 0.026
tissue morphogenesis GO:0048729 297 0.026
regulation of synapse structure and activity GO:0050803 128 0.026
protein heterooligomerization GO:0051291 4 0.026
skin development GO:0043588 65 0.026
cellular response to chemical stimulus GO:0070887 199 0.025
negative regulation of cell cycle GO:0045786 116 0.025
regulation of stress activated protein kinase signaling cascade GO:0070302 42 0.025
cell cycle checkpoint GO:0000075 95 0.025
eye development GO:0001654 323 0.025
regulation of jnk cascade GO:0046328 40 0.025
proteasomal protein catabolic process GO:0010498 59 0.025
enzyme linked receptor protein signaling pathway GO:0007167 179 0.025
homeostatic process GO:0042592 199 0.025
negative regulation of cell cycle process GO:0010948 109 0.024
negative regulation of nervous system development GO:0051961 92 0.024
regulation of meiosis GO:0040020 3 0.024
meiotic nuclear division GO:0007126 151 0.024
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.024
single organism intracellular transport GO:1902582 207 0.023
negative regulation of fibroblast growth factor receptor signaling pathway GO:0040037 2 0.023
positive regulation of signal transduction GO:0009967 223 0.023
regulation of lipid metabolic process GO:0019216 15 0.023
dna replication GO:0006260 48 0.023
carbohydrate metabolic process GO:0005975 82 0.023
organic acid metabolic process GO:0006082 103 0.023
ubiquitin dependent protein catabolic process GO:0006511 78 0.023
protein modification by small protein conjugation GO:0032446 79 0.022
regulation of localization GO:0032879 275 0.022
neuroblast division GO:0055057 35 0.022
autophagic cell death GO:0048102 83 0.022
stem cell differentiation GO:0048863 117 0.022
posttranscriptional gene silencing GO:0016441 46 0.022
protein localization GO:0008104 284 0.022
embryo development ending in birth or egg hatching GO:0009792 152 0.022
organonitrogen compound metabolic process GO:1901564 318 0.022
cell cycle phase transition GO:0044770 140 0.022
signal transduction by phosphorylation GO:0023014 107 0.022
positive regulation of phosphorylation GO:0042327 87 0.022
carboxylic acid metabolic process GO:0019752 92 0.022
regulation of canonical wnt signaling pathway GO:0060828 15 0.021
phagocytosis GO:0006909 215 0.021
cellular lipid metabolic process GO:0044255 83 0.021
wing disc morphogenesis GO:0007472 344 0.021
neurological system process GO:0050877 358 0.021
epithelial cell differentiation GO:0030855 322 0.021
regulation of response to extracellular stimulus GO:0032104 18 0.021
neuroblast differentiation GO:0014016 29 0.020
cell aging GO:0007569 2 0.020
negative regulation of developmental growth GO:0048640 64 0.020
salivary gland morphogenesis GO:0007435 145 0.020
regulation of immune system process GO:0002682 176 0.020
positive regulation of phosphate metabolic process GO:0045937 139 0.020
regulation of wnt signaling pathway GO:0030111 68 0.020
single organism biosynthetic process GO:0044711 206 0.020
negative regulation of cellular biosynthetic process GO:0031327 277 0.020
negative regulation of g2 m transition of mitotic cell cycle GO:0010972 8 0.020
salivary gland cell autophagic cell death GO:0035071 83 0.019
chaeta development GO:0022416 97 0.019
development of primary sexual characteristics GO:0045137 50 0.019
regulation of lipid kinase activity GO:0043550 2 0.019
cellular macromolecule catabolic process GO:0044265 136 0.019
positive regulation of protein kinase activity GO:0045860 25 0.019
organic substance catabolic process GO:1901575 308 0.019
cellular response to sterol depletion GO:0071501 3 0.019
positive regulation of multicellular organism growth GO:0040018 21 0.019
response to light stimulus GO:0009416 124 0.019
positive regulation of intracellular signal transduction GO:1902533 116 0.019
organic hydroxy compound metabolic process GO:1901615 83 0.019
gliogenesis GO:0042063 80 0.019
response to x ray GO:0010165 8 0.019
stress activated protein kinase signaling cascade GO:0031098 55 0.019
cellular response to dna damage stimulus GO:0006974 223 0.018
establishment or maintenance of cell polarity GO:0007163 167 0.018
chromosome separation GO:0051304 42 0.018
cell cycle arrest GO:0007050 4 0.018
response to uv GO:0009411 24 0.018
sex differentiation GO:0007548 81 0.018
ubiquitin homeostasis GO:0010992 1 0.018
autophagic vacuole assembly GO:0000045 2 0.018
regulation of neurogenesis GO:0050767 158 0.018
glutamate secretion GO:0014047 1 0.017
chromatin organization GO:0006325 207 0.017
axon development GO:0061564 297 0.017
positive regulation of apoptotic signaling pathway GO:2001235 4 0.017
positive regulation of cell death GO:0010942 69 0.017
regulation of anatomical structure size GO:0090066 163 0.017
regulation of epithelial cell proliferation GO:0050678 4 0.017
regulation of imaginal disc growth GO:0045570 26 0.017
mitotic dna damage checkpoint GO:0044773 74 0.017
actin cytoskeleton organization GO:0030036 206 0.017
positive regulation of response to nutrient levels GO:0032109 8 0.017
defense response to gram negative bacterium GO:0050829 94 0.017
negative regulation of response to stimulus GO:0048585 258 0.017
cellular ketone metabolic process GO:0042180 24 0.017
negative regulation of epidermal growth factor receptor signaling pathway GO:0042059 29 0.017
regulation of mitotic sister chromatid segregation GO:0033047 28 0.017
histone modification GO:0016570 106 0.016
response to radiation GO:0009314 155 0.016
negative regulation of synapse assembly GO:0051964 39 0.016
extrinsic apoptotic signaling pathway GO:0097191 1 0.016
regulation of autophagy GO:0010506 62 0.016
small molecule metabolic process GO:0044281 305 0.016
negative regulation of cellular component organization GO:0051129 108 0.016
negative regulation of homeostatic process GO:0032845 2 0.016
developmental programmed cell death GO:0010623 138 0.016
post embryonic appendage morphogenesis GO:0035120 385 0.016
regulation of notch signaling pathway GO:0008593 100 0.016
urogenital system development GO:0001655 72 0.016
regulation of epithelial cell differentiation GO:0030856 4 0.016
compound eye morphogenesis GO:0001745 249 0.016
innate immune response GO:0045087 144 0.015
modification dependent protein catabolic process GO:0019941 78 0.015
appendage development GO:0048736 401 0.015
sister chromatid segregation GO:0000819 92 0.015
reciprocal meiotic recombination GO:0007131 19 0.015
peptidyl tyrosine modification GO:0018212 24 0.015
regulation of synaptic growth at neuromuscular junction GO:0008582 89 0.015
regulation of phosphatidylinositol 3 kinase activity GO:0043551 2 0.015
chromatin modification GO:0016568 147 0.015
negative regulation of phosphate metabolic process GO:0045936 45 0.015
negative regulation of protein processing GO:0010955 31 0.015
regulation of erk1 and erk2 cascade GO:0070372 39 0.014
developmental maturation GO:0021700 172 0.014
generation of precursor metabolites and energy GO:0006091 42 0.014
cellular response to hormone stimulus GO:0032870 44 0.014
multi multicellular organism process GO:0044706 123 0.014
positive regulation of mapk cascade GO:0043410 63 0.014
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 4 0.014
posttranscriptional gene silencing by rna GO:0035194 45 0.014
meiotic dna double strand break formation GO:0042138 1 0.014
meiotic cell cycle GO:0051321 171 0.014
regulation of neural precursor cell proliferation GO:2000177 35 0.014
reproductive structure development GO:0048608 74 0.014
regulation of cellular ketone metabolic process GO:0010565 3 0.014
single organism behavior GO:0044708 391 0.014
regulation of molecular function GO:0065009 217 0.014
smoothened signaling pathway GO:0007224 49 0.014
salivary gland histolysis GO:0035070 88 0.014
mitochondrion degradation GO:0000422 8 0.014
regulation of mitotic sister chromatid separation GO:0010965 28 0.014
protein processing GO:0016485 68 0.014
negative regulation of meiotic cell cycle GO:0051447 2 0.014
negative regulation of phosphorus metabolic process GO:0010563 45 0.014
heterocycle catabolic process GO:0046700 166 0.013
canonical wnt signaling pathway GO:0060070 21 0.013
regulation of establishment of protein localization GO:0070201 61 0.013
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 25 0.013
regulation of neuron death GO:1901214 26 0.013
intraspecies interaction between organisms GO:0051703 4 0.013
glycosyl compound catabolic process GO:1901658 112 0.013
reciprocal dna recombination GO:0035825 19 0.013
intracellular mrna localization involved in pattern specification process GO:0060810 56 0.013
multicellular organismal reproductive behavior GO:0033057 110 0.013
positive regulation of cell size GO:0045793 21 0.013
actin filament based process GO:0030029 220 0.013
establishment of planar polarity GO:0001736 87 0.013
cellular nitrogen compound catabolic process GO:0044270 165 0.013
regionalization GO:0003002 416 0.013
regulation of protein catabolic process GO:0042176 55 0.012
response to ionizing radiation GO:0010212 32 0.012
ras protein signal transduction GO:0007265 88 0.012
intracellular transport GO:0046907 228 0.012
mitotic cell cycle checkpoint GO:0007093 88 0.012
cellular response to organic substance GO:0071310 132 0.012
positive regulation of cell proliferation GO:0008284 47 0.012
regulation of organ growth GO:0046620 42 0.012
negative regulation of cell cycle phase transition GO:1901988 103 0.012
skeletal muscle organ development GO:0060538 48 0.012
amine metabolic process GO:0009308 12 0.012
dna dependent dna replication GO:0006261 17 0.012
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 73 0.012
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.011
larval development GO:0002164 104 0.011
cellular amine metabolic process GO:0044106 12 0.011
protein maturation GO:0051604 71 0.011
regulation of cellular response to oxidative stress GO:1900407 4 0.011
peptidyl threonine phosphorylation GO:0018107 2 0.011
nucleus organization GO:0006997 45 0.011
positive regulation of transferase activity GO:0051347 26 0.011
pole plasm oskar mrna localization GO:0045451 46 0.011
dendrite morphogenesis GO:0048813 199 0.011
regulation of mapk cascade GO:0043408 92 0.011
g2 m transition of mitotic cell cycle GO:0000086 19 0.011
stem cell proliferation GO:0072089 88 0.011
chemical homeostasis GO:0048878 92 0.011
regulation of nuclear division GO:0051783 58 0.011
response to calcium ion GO:0051592 1 0.011
negative regulation of proteolysis GO:0045861 31 0.011
positive regulation of protein phosphorylation GO:0001934 34 0.011
organic cyclic compound catabolic process GO:1901361 168 0.011
regulation of cellular localization GO:0060341 136 0.011
mapk cascade GO:0000165 107 0.011
activation of protein kinase activity GO:0032147 12 0.011
negative regulation of intracellular signal transduction GO:1902532 57 0.011
cellular response to carbohydrate stimulus GO:0071322 4 0.011
cellular macromolecule localization GO:0070727 220 0.011
double strand break repair GO:0006302 26 0.011
regulation of synaptic vesicle recycling GO:1903421 7 0.010
germ line stem cell maintenance GO:0030718 50 0.010
intracellular mrna localization GO:0008298 66 0.010
sterol homeostasis GO:0055092 4 0.010
pole plasm assembly GO:0007315 61 0.010
positive regulation of autophagy GO:0010508 21 0.010
myotube cell development GO:0014904 3 0.010
nuclear export GO:0051168 24 0.010
defense response to other organism GO:0098542 225 0.010
peptide metabolic process GO:0006518 80 0.010
body morphogenesis GO:0010171 2 0.010

Ptp61F disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.013
central nervous system disease DOID:331 0 0.010
nervous system disease DOID:863 0 0.010