Drosophila melanogaster

162 known processes

Mcm10 (Dmel_CG9241)

Sensitized chromosome inheritance modifier 19

(Aliases: CG9241,mcm10,Dmel\CG9241,Scim19,DmMCM10)

Mcm10 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
chromosome organization GO:0051276 360 0.999
mitotic sister chromatid segregation GO:0000070 87 0.990
chromosome segregation GO:0007059 157 0.892
mitotic sister chromatid separation GO:0051306 30 0.835
regulation of mitotic sister chromatid segregation GO:0033047 28 0.819
sister chromatid segregation GO:0000819 92 0.819
dna metabolic process GO:0006259 227 0.815
nuclear dna replication GO:0033260 1 0.810
nuclear division GO:0000280 332 0.770
regulation of metaphase anaphase transition of cell cycle GO:1902099 26 0.757
dna conformation change GO:0071103 105 0.734
cell cycle phase transition GO:0044770 140 0.732
regulation of mitotic cell cycle GO:0007346 190 0.697
dna endoreduplication GO:0042023 22 0.680
negative regulation of cellular metabolic process GO:0031324 382 0.664
mitotic nuclear division GO:0007067 213 0.646
chromatin organization GO:0006325 207 0.561
metaphase anaphase transition of cell cycle GO:0044784 28 0.555
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.549
mitotic cell cycle phase transition GO:0044772 138 0.543
organelle fission GO:0048285 340 0.533
positive regulation of metaphase anaphase transition of cell cycle GO:1902101 10 0.530
regulation of mitotic sister chromatid separation GO:0010965 28 0.509
covalent chromatin modification GO:0016569 106 0.476
regulation of cellular catabolic process GO:0031329 157 0.475
regulation of mitotic cell cycle phase transition GO:1901990 130 0.466
cell cycle dna replication GO:0044786 23 0.457
eye morphogenesis GO:0048592 260 0.454
dna packaging GO:0006323 91 0.446
regulation of sister chromatid segregation GO:0033045 28 0.437
eggshell chorion gene amplification GO:0007307 9 0.425
dna amplification GO:0006277 11 0.394
chromosome separation GO:0051304 42 0.370
regulation of mitotic metaphase anaphase transition GO:0030071 26 0.367
gene silencing GO:0016458 138 0.358
dna replication GO:0006260 48 0.315
cell cycle checkpoint GO:0000075 95 0.314
cellular response to dna damage stimulus GO:0006974 223 0.292
meiotic chromosome segregation GO:0045132 59 0.285
regulation of chromosome segregation GO:0051983 32 0.280
positive regulation of mitotic sister chromatid separation GO:1901970 10 0.272
negative regulation of biosynthetic process GO:0009890 277 0.261
mitotic cell cycle checkpoint GO:0007093 88 0.255
chromosome condensation GO:0030261 41 0.229
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.224
meiotic nuclear division GO:0007126 151 0.222
regulation of catabolic process GO:0009894 170 0.219
chromatin modification GO:0016568 147 0.212
regulation of cell cycle process GO:0010564 181 0.211
metaphase anaphase transition of mitotic cell cycle GO:0007091 28 0.200
recombinational repair GO:0000725 13 0.179
negative regulation of cell cycle process GO:0010948 109 0.175
negative regulation of mitotic cell cycle GO:0045930 109 0.174
regulation of proteasomal protein catabolic process GO:0061136 39 0.170
protein dna complex assembly GO:0065004 63 0.164
centrosome cycle GO:0007098 137 0.161
regulation of chromosome organization GO:0033044 64 0.157
regulation of gene expression epigenetic GO:0040029 128 0.154
negative regulation of gene expression GO:0010629 387 0.152
regulation of proteolysis GO:0030162 87 0.151
mitotic chromosome condensation GO:0007076 22 0.151
spindle organization GO:0007051 253 0.147
positive regulation of dna endoreduplication GO:0032877 4 0.132
positive regulation of proteolysis GO:0045862 52 0.127
compound eye morphogenesis GO:0001745 249 0.126
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.125
proteasomal protein catabolic process GO:0010498 59 0.120
small molecule metabolic process GO:0044281 305 0.119
positive regulation of cell cycle GO:0045787 43 0.116
single organism biosynthetic process GO:0044711 206 0.113
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 37 0.112
cellular catabolic process GO:0044248 372 0.112
positive regulation of mitotic metaphase anaphase transition GO:0045842 10 0.111
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 44 0.111
negative regulation of mitotic sister chromatid separation GO:2000816 13 0.108
negative regulation of mitotic sister chromatid segregation GO:0033048 13 0.105
regulation of nuclear division GO:0051783 58 0.097
chromatin remodeling GO:0006338 72 0.096
nucleosome organization GO:0034728 59 0.092
negative regulation of cellular biosynthetic process GO:0031327 277 0.087
dna replication initiation GO:0006270 6 0.087
notch signaling pathway GO:0007219 120 0.084
posttranscriptional gene silencing by rna GO:0035194 45 0.083
negative regulation of cellular protein metabolic process GO:0032269 85 0.080
regulation of cell cycle phase transition GO:1901987 130 0.076
cellular protein catabolic process GO:0044257 83 0.076
mitotic metaphase plate congression GO:0007080 13 0.074
posttranscriptional regulation of gene expression GO:0010608 145 0.074
mitotic spindle organization GO:0007052 220 0.074
regulation of phosphate metabolic process GO:0019220 210 0.073
developmental growth GO:0048589 280 0.073
centrosome duplication GO:0051298 121 0.072
regulation of neuron differentiation GO:0045664 103 0.070
regulation of cellular protein catabolic process GO:1903362 44 0.069
nucleosome assembly GO:0006334 35 0.068
double strand break repair GO:0006302 26 0.067
cell cell signaling involved in cell fate commitment GO:0045168 210 0.067
ras protein signal transduction GO:0007265 88 0.066
regulation of g1 s transition of mitotic cell cycle GO:2000045 23 0.066
phosphorylation GO:0016310 294 0.065
regulation of cell cycle GO:0051726 291 0.064
positive regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032436 19 0.063
spindle checkpoint GO:0031577 11 0.061
glial cell differentiation GO:0010001 35 0.060
positive regulation of cellular catabolic process GO:0031331 95 0.059
mitotic cell cycle embryonic GO:0045448 38 0.058
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.058
organonitrogen compound metabolic process GO:1901564 318 0.058
body morphogenesis GO:0010171 2 0.058
cellular protein modification process GO:0006464 438 0.058
regulation of mitosis GO:0007088 56 0.057
dna geometric change GO:0032392 16 0.056
positive regulation of macromolecule metabolic process GO:0010604 405 0.056
response to temperature stimulus GO:0009266 106 0.054
heterochromatin organization GO:0070828 25 0.054
establishment of organelle localization GO:0051656 122 0.053
regulation of meiosis GO:0040020 3 0.053
mitotic spindle assembly checkpoint GO:0007094 11 0.053
spindle assembly checkpoint GO:0071173 11 0.053
peptidyl amino acid modification GO:0018193 105 0.052
dna dependent dna replication GO:0006261 17 0.051
regulation of protein catabolic process GO:0042176 55 0.051
maintenance of location GO:0051235 73 0.051
regulation of microtubule cytoskeleton organization GO:0070507 41 0.051
epithelial cell differentiation GO:0030855 322 0.051
negative regulation of cell cycle phase transition GO:1901988 103 0.051
compound eye development GO:0048749 307 0.050
negative regulation of neurogenesis GO:0050768 53 0.049
positive regulation of multicellular organismal process GO:0051240 143 0.048
protein phosphorylation GO:0006468 169 0.048
regulation of photoreceptor cell differentiation GO:0046532 34 0.047
organic substance catabolic process GO:1901575 308 0.045
histone modification GO:0016570 106 0.044
protein modification process GO:0036211 438 0.043
regulation of developmental growth GO:0048638 174 0.043
eye development GO:0001654 323 0.043
dna duplex unwinding GO:0032508 16 0.043
sensory organ morphogenesis GO:0090596 260 0.042
negative regulation of chromosome segregation GO:0051985 14 0.042
lymph gland development GO:0048542 28 0.042
nucleoside phosphate metabolic process GO:0006753 162 0.042
regulation of dna replication GO:0006275 13 0.041
ribonucleoside metabolic process GO:0009119 127 0.041
posttranscriptional gene silencing GO:0016441 46 0.041
somatic stem cell division GO:0048103 37 0.041
gliogenesis GO:0042063 80 0.040
carbohydrate derivative metabolic process GO:1901135 217 0.040
digestive system development GO:0055123 149 0.040
positive regulation of mitotic cell cycle GO:0045931 34 0.039
negative regulation of protein metabolic process GO:0051248 85 0.038
cell proliferation GO:0008283 299 0.038
innate immune response GO:0045087 144 0.038
cell division GO:0051301 248 0.037
single organism catabolic process GO:0044712 228 0.037
proteolysis GO:0006508 192 0.037
regulation of sister chromatid cohesion GO:0007063 2 0.037
telomere capping GO:0016233 11 0.036
purine containing compound metabolic process GO:0072521 155 0.036
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.036
purine nucleotide metabolic process GO:0006163 146 0.035
positive regulation of nucleotide metabolic process GO:0045981 55 0.035
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.035
negative regulation of multicellular organismal process GO:0051241 142 0.035
positive regulation of catabolic process GO:0009896 105 0.034
chromatin silencing GO:0006342 76 0.034
nucleolus organization GO:0007000 4 0.034
ubiquitin dependent protein catabolic process GO:0006511 78 0.034
multicellular organism growth GO:0035264 46 0.034
regulation of lipid metabolic process GO:0019216 15 0.033
regulation of apoptotic process GO:0042981 130 0.033
negative regulation of sister chromatid segregation GO:0033046 13 0.033
endomitotic cell cycle GO:0007113 7 0.032
positive regulation of nucleotide catabolic process GO:0030813 46 0.032
intracellular signal transduction GO:0035556 300 0.032
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.032
regulation of protein metabolic process GO:0051246 256 0.032
mitotic dna damage checkpoint GO:0044773 74 0.031
asymmetric stem cell division GO:0098722 49 0.031
protein maturation GO:0051604 71 0.031
ribonucleotide metabolic process GO:0009259 145 0.031
mitotic spindle checkpoint GO:0071174 11 0.031
small gtpase mediated signal transduction GO:0007264 88 0.031
positive regulation of hydrolase activity GO:0051345 78 0.030
catabolic process GO:0009056 409 0.030
positive regulation of response to stimulus GO:0048584 323 0.029
positive regulation of signal transduction GO:0009967 223 0.028
microtubule organizing center organization GO:0031023 168 0.027
response to biotic stimulus GO:0009607 294 0.027
ribose phosphate metabolic process GO:0019693 145 0.027
purine nucleoside metabolic process GO:0042278 127 0.027
purine nucleoside triphosphate catabolic process GO:0009146 108 0.027
organophosphate metabolic process GO:0019637 195 0.027
purine ribonucleotide metabolic process GO:0009150 145 0.027
positive regulation of neurogenesis GO:0050769 41 0.027
purine ribonucleotide catabolic process GO:0009154 109 0.027
female meiotic division GO:0007143 70 0.026
female meiosis chromosome segregation GO:0016321 33 0.026
regulation of gene silencing GO:0060968 63 0.026
larval development GO:0002164 104 0.026
karyosome formation GO:0030717 22 0.026
dna damage checkpoint GO:0000077 78 0.026
histone methylation GO:0016571 40 0.025
telomere organization GO:0032200 21 0.025
lateral inhibition GO:0046331 206 0.025
double strand break repair via homologous recombination GO:0000724 13 0.025
epithelial cell development GO:0002064 274 0.025
nucleobase containing compound catabolic process GO:0034655 165 0.025
endomembrane system organization GO:0010256 119 0.024
positive regulation of organelle organization GO:0010638 65 0.024
homeostatic process GO:0042592 199 0.024
nucleoside catabolic process GO:0009164 112 0.024
negative regulation of cellular catabolic process GO:0031330 34 0.024
purine ribonucleoside metabolic process GO:0046128 127 0.024
regulation of catalytic activity GO:0050790 185 0.024
negative regulation of catabolic process GO:0009895 36 0.024
purine containing compound catabolic process GO:0072523 112 0.023
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.023
positive regulation of protein metabolic process GO:0051247 128 0.023
regulation of hydrolase activity GO:0051336 97 0.023
muscle organ development GO:0007517 127 0.023
purine nucleoside catabolic process GO:0006152 112 0.022
cellular macromolecule catabolic process GO:0044265 136 0.022
regulation of chromatin silencing GO:0031935 36 0.022
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.022
cell motility GO:0048870 251 0.022
negative regulation of cell cycle GO:0045786 116 0.022
nucleoside triphosphate metabolic process GO:0009141 120 0.022
positive regulation of phosphorus metabolic process GO:0010562 139 0.022
cell fate determination GO:0001709 91 0.022
aromatic compound catabolic process GO:0019439 166 0.022
dna integrity checkpoint GO:0031570 81 0.021
kinetochore organization GO:0051383 9 0.021
mesoderm development GO:0007498 78 0.021
fatty acid homeostasis GO:0055089 2 0.021
regulation of cellular protein metabolic process GO:0032268 243 0.021
regulation of multicellular organismal development GO:2000026 414 0.021
nucleoside metabolic process GO:0009116 127 0.021
negative regulation of chromosome organization GO:2001251 19 0.021
spindle assembly GO:0051225 80 0.021
columnar cuboidal epithelial cell development GO:0002066 249 0.021
regulation of neurogenesis GO:0050767 158 0.020
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process GO:0031145 30 0.020
regulation of cell death GO:0010941 173 0.020
positive regulation of chromosome segregation GO:0051984 10 0.020
negative regulation of transcription dna templated GO:0045892 237 0.020
negative regulation of signal transduction GO:0009968 206 0.020
female germ line stem cell asymmetric division GO:0048132 14 0.020
response to external biotic stimulus GO:0043207 293 0.020
ribonucleotide catabolic process GO:0009261 109 0.020
nucleosome mobilization GO:0042766 9 0.020
positive regulation of mitotic cell cycle phase transition GO:1901992 20 0.019
ribonucleoside catabolic process GO:0042454 112 0.019
photoreceptor cell differentiation GO:0046530 170 0.019
positive regulation of nucleoside metabolic process GO:0045979 47 0.019
heterocycle catabolic process GO:0046700 166 0.018
regulation of phosphorus metabolic process GO:0051174 210 0.018
establishment of localization in cell GO:0051649 402 0.018
regulation of cell development GO:0060284 215 0.018
sensory organ precursor cell division GO:0045035 10 0.018
organ growth GO:0035265 56 0.018
carbohydrate derivative catabolic process GO:1901136 118 0.018
organic cyclic compound catabolic process GO:1901361 168 0.017
macromolecular complex assembly GO:0065003 256 0.017
atp metabolic process GO:0046034 49 0.017
glial cell development GO:0021782 27 0.017
positive regulation of phosphate metabolic process GO:0045937 139 0.017
regulation of localization GO:0032879 275 0.017
meiotic cell cycle GO:0051321 171 0.017
heterochromatin assembly GO:0031507 13 0.017
regulation of growth GO:0040008 233 0.017
organonitrogen compound catabolic process GO:1901565 128 0.017
negative regulation of organelle organization GO:0010639 56 0.017
regulation of nucleotide metabolic process GO:0006140 62 0.017
protein dna complex subunit organization GO:0071824 86 0.016
regulation of cell proliferation GO:0042127 163 0.016
regulation of protein processing GO:0070613 32 0.016
nuclear migration GO:0007097 20 0.016
glycosyl compound catabolic process GO:1901658 112 0.016
regulation of hemocyte proliferation GO:0035206 37 0.016
nucleobase containing small molecule metabolic process GO:0055086 174 0.015
positive regulation of growth GO:0045927 75 0.015
positive regulation of cell proliferation GO:0008284 47 0.015
nucleoside monophosphate metabolic process GO:0009123 52 0.015
negative regulation of mitotic metaphase anaphase transition GO:0045841 13 0.015
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.015
axon development GO:0061564 297 0.015
positive regulation of proteolysis involved in cellular protein catabolic process GO:1903052 24 0.015
positive regulation of cell development GO:0010720 61 0.015
mitotic sister chromatid cohesion GO:0007064 6 0.015
response to organophosphorus GO:0046683 2 0.015
protein catabolic process GO:0030163 101 0.014
nucleotide metabolic process GO:0009117 161 0.014
response to heat GO:0009408 63 0.014
regulation of ras protein signal transduction GO:0046578 93 0.014
eye photoreceptor cell differentiation GO:0001754 145 0.014
neural precursor cell proliferation GO:0061351 75 0.014
regulation of cell size GO:0008361 63 0.014
protein modification by small protein conjugation GO:0032446 79 0.014
carboxylic acid metabolic process GO:0019752 92 0.014
protein complex biogenesis GO:0070271 201 0.014
ribonucleoside triphosphate metabolic process GO:0009199 119 0.014
protein import into nucleus GO:0006606 51 0.014
positive regulation of cysteine type endopeptidase activity GO:2001056 24 0.014
positive regulation of molecular function GO:0044093 136 0.014
modification dependent macromolecule catabolic process GO:0043632 79 0.014
regulation of purine nucleotide catabolic process GO:0033121 48 0.014
localization of cell GO:0051674 257 0.014
chromatin maintenance GO:0070827 2 0.013
regulation of cell cycle g1 s phase transition GO:1902806 23 0.013
nucleoside phosphate catabolic process GO:1901292 110 0.013
wnt signaling pathway GO:0016055 98 0.013
mitotic cytokinesis GO:0000281 50 0.013
negative regulation of mitosis GO:0045839 16 0.013
regulation of centrosome cycle GO:0046605 7 0.013
positive regulation of cellular biosynthetic process GO:0031328 316 0.013
macromolecule catabolic process GO:0009057 161 0.013
negative regulation of cellular component organization GO:0051129 108 0.013
nucleotide catabolic process GO:0009166 109 0.013
actin filament based process GO:0030029 220 0.013
negative regulation of protein modification process GO:0031400 29 0.013
dephosphorylation GO:0016311 51 0.013
regulation of organelle organization GO:0033043 196 0.013
spermatogenesis GO:0007283 200 0.013
regulation of purine nucleotide metabolic process GO:1900542 62 0.012
regulation of dna metabolic process GO:0051052 34 0.012
modification dependent protein catabolic process GO:0019941 78 0.012
regulation of nucleotide catabolic process GO:0030811 48 0.012
single organism nuclear import GO:1902593 51 0.012
positive regulation of cellular protein metabolic process GO:0032270 118 0.012
regulation of cytoskeleton organization GO:0051493 89 0.012
negative regulation of rna metabolic process GO:0051253 251 0.012
imaginal disc growth GO:0007446 37 0.012
appendage morphogenesis GO:0035107 397 0.012
gene silencing by rna GO:0031047 57 0.012
negative regulation of programmed cell death GO:0043069 72 0.012
negative regulation of developmental process GO:0051093 201 0.012
gtp catabolic process GO:0006184 72 0.011
nucleosome positioning GO:0016584 3 0.011
signal release GO:0023061 49 0.011
protein complex assembly GO:0006461 200 0.011
cystoblast division GO:0007282 10 0.011
purine nucleoside triphosphate metabolic process GO:0009144 119 0.011
spindle assembly involved in mitosis GO:0090307 50 0.011
positive regulation of cell communication GO:0010647 250 0.011
cell aging GO:0007569 2 0.011
positive regulation of proteasomal protein catabolic process GO:1901800 20 0.011
regulation of transcription by chromatin organization GO:0034401 3 0.011
cell cycle comprising mitosis without cytokinesis GO:0033301 25 0.011
negative regulation of cell division GO:0051782 17 0.011
glial cell migration GO:0008347 31 0.011
chemical homeostasis GO:0048878 92 0.011
g1 s transition of mitotic cell cycle GO:0000082 31 0.011
negative regulation of neuron differentiation GO:0045665 16 0.011
regulation of protein stability GO:0031647 43 0.011
methylation GO:0032259 47 0.011
response to other organism GO:0051707 293 0.011
positive regulation of cellular protein catabolic process GO:1903364 24 0.010
camera type eye morphogenesis GO:0048593 2 0.010
stem cell differentiation GO:0048863 117 0.010
regulation of cysteine type endopeptidase activity GO:2000116 27 0.010
synaptic vesicle recycling GO:0036465 28 0.010
g2 m transition of mitotic cell cycle GO:0000086 19 0.010
organic acid metabolic process GO:0006082 103 0.010
histone lysine methylation GO:0034968 32 0.010
ion homeostasis GO:0050801 55 0.010
dna recombination GO:0006310 32 0.010

Mcm10 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.019
disease of anatomical entity DOID:7 0 0.019
cancer DOID:162 0 0.011
organ system cancer DOID:0050686 0 0.011
musculoskeletal system cancer DOID:0060100 0 0.011