Drosophila melanogaster

15 known processes

RPA2 (Dmel_CG9273)

Replication protein A2

(Aliases: Dmel\CG9273,153194_at,dRPA2,CG9273)

RPA2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
spindle organization GO:0007051 253 0.919
regulation of neurogenesis GO:0050767 158 0.872
double strand break repair via nonhomologous end joining GO:0006303 5 0.819
mitotic dna damage checkpoint GO:0044773 74 0.698
Human
non recombinational repair GO:0000726 7 0.666
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.486
Human
dna repair GO:0006281 54 0.395
Human
mitotic spindle organization GO:0007052 220 0.315
chromosome organization GO:0051276 360 0.264
Human
dna dependent dna replication GO:0006261 17 0.211
nuclear division GO:0000280 332 0.186
regulation of mitotic cell cycle GO:0007346 190 0.184
Human
dendrite development GO:0016358 204 0.181
negative regulation of meiotic cell cycle GO:0051447 2 0.177
anatomical structure homeostasis GO:0060249 97 0.174
Human
dna recombination GO:0006310 32 0.172
Human
germ line cyst formation GO:0048134 44 0.169
mrna processing GO:0006397 104 0.162
immune system process GO:0002376 347 0.159
regulation of cell cycle phase transition GO:1901987 130 0.158
Human
dna replication GO:0006260 48 0.156
Human
dna damage checkpoint GO:0000077 78 0.149
Human
mitotic cell cycle checkpoint GO:0007093 88 0.137
Human
regulation of dna recombination GO:0000018 4 0.135
Human
regulation of mitotic cell cycle phase transition GO:1901990 130 0.129
Human
immune response GO:0006955 246 0.125
axon development GO:0061564 297 0.114
regulation of ras protein signal transduction GO:0046578 93 0.114
negative regulation of cell cycle process GO:0010948 109 0.113
Human
double strand break repair GO:0006302 26 0.112
Human
negative regulation of gene expression GO:0010629 387 0.111
mitotic g2 dna damage checkpoint GO:0007095 69 0.110
cellular response to dna damage stimulus GO:0006974 223 0.106
Human
chromatin organization GO:0006325 207 0.099
mitotic g2 m transition checkpoint GO:0044818 70 0.099
telomere maintenance GO:0000723 21 0.097
Human
dendrite morphogenesis GO:0048813 199 0.096
vesicle mediated transport GO:0016192 381 0.096
regulation of intracellular signal transduction GO:1902531 236 0.095
rna processing GO:0006396 147 0.093
g2 dna damage checkpoint GO:0031572 69 0.090
phosphorylation of rna polymerase ii c terminal domain GO:0070816 1 0.090
rna capping GO:0036260 1 0.087
negative regulation of cell cycle phase transition GO:1901988 103 0.086
Human
double strand break repair via homologous recombination GO:0000724 13 0.080
Human
positive regulation of developmental process GO:0051094 143 0.079
cell cycle g1 s phase transition GO:0044843 31 0.071
Human
chromatin modification GO:0016568 147 0.066
gene silencing GO:0016458 138 0.064
regulation of cell differentiation GO:0045595 302 0.059
regulation of response to stress GO:0080134 200 0.059
Human
negative regulation of mitotic cell cycle GO:0045930 109 0.057
Human
positive regulation of cellular catabolic process GO:0031331 95 0.051
hematopoietic stem cell differentiation GO:0060218 1 0.050
positive regulation of lipid catabolic process GO:0050996 1 0.049
regulation of double strand break repair GO:2000779 3 0.048
Human
neuronal stem cell maintenance GO:0097150 4 0.047
dna metabolic process GO:0006259 227 0.043
Human
mitotic cell cycle phase transition GO:0044772 138 0.043
Human
regulation of neuron differentiation GO:0045664 103 0.042
regulation of nervous system development GO:0051960 248 0.039
actin cytoskeleton organization GO:0030036 206 0.039
sister chromatid cohesion GO:0007062 18 0.038
intermediate filament based process GO:0045103 1 0.038
regulation of small gtpase mediated signal transduction GO:0051056 93 0.037
intracellular signal transduction GO:0035556 300 0.037
mrna metabolic process GO:0016071 124 0.036
homeostatic process GO:0042592 199 0.034
Human
regulation of cell cycle GO:0051726 291 0.034
Human
organic cyclic compound catabolic process GO:1901361 168 0.033
regulation of protein transport GO:0051223 57 0.033
regulation of cytoplasmic transport GO:1903649 47 0.032
regulation of molecular function GO:0065009 217 0.032
posttranscriptional gene silencing GO:0016441 46 0.031
aromatic compound catabolic process GO:0019439 166 0.031
axis specification GO:0009798 167 0.030
regulation of intracellular protein transport GO:0033157 46 0.030
endocytosis GO:0006897 310 0.030
negative regulation of cellular biosynthetic process GO:0031327 277 0.030
small gtpase mediated signal transduction GO:0007264 88 0.030
nuclear import GO:0051170 51 0.029
centrosome organization GO:0051297 163 0.029
cell cycle phase transition GO:0044770 140 0.029
Human
ras protein signal transduction GO:0007265 88 0.029
developmental growth GO:0048589 280 0.028
heterocycle catabolic process GO:0046700 166 0.028
single organism biosynthetic process GO:0044711 206 0.028
regulation of double strand break repair via homologous recombination GO:0010569 2 0.027
Human
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 73 0.027
formation of a compartment boundary GO:0060288 4 0.027
female germ line cyst formation GO:0048135 42 0.027
positive regulation of protein transport GO:0051222 37 0.027
regulation of ras gtpase activity GO:0032318 38 0.027
neuroblast proliferation GO:0007405 74 0.027
positive regulation of gtpase activity GO:0043547 43 0.026
organ growth GO:0035265 56 0.026
phagocytosis GO:0006909 215 0.026
dna integrity checkpoint GO:0031570 81 0.025
Human
regulation of nucleocytoplasmic transport GO:0046822 35 0.025
response to oxygen containing compound GO:1901700 200 0.025
regulation of dendrite development GO:0050773 37 0.025
recombinational repair GO:0000725 13 0.025
Human
central nervous system development GO:0007417 201 0.025
establishment of localization in cell GO:0051649 402 0.024
catabolic process GO:0009056 409 0.024
regulation of gtp catabolic process GO:0033124 44 0.024
segmentation GO:0035282 207 0.024
negative regulation of cellular metabolic process GO:0031324 382 0.024
response to biotic stimulus GO:0009607 294 0.024
embryonic axis specification GO:0000578 107 0.023
stem cell differentiation GO:0048863 117 0.023
microtubule organizing center organization GO:0031023 168 0.023
regulation of gene expression epigenetic GO:0040029 128 0.023
regulation of intracellular transport GO:0032386 64 0.023
spindle assembly GO:0051225 80 0.023
locomotory behavior GO:0007626 176 0.022
protein localization GO:0008104 284 0.022
protein targeting to nucleus GO:0044744 51 0.022
intracellular protein transport GO:0006886 104 0.022
positive regulation of catalytic activity GO:0043085 118 0.021
protein transport GO:0015031 155 0.021
negative regulation of nucleic acid templated transcription GO:1903507 240 0.021
telomere organization GO:0032200 21 0.020
Human
negative regulation of response to stimulus GO:0048585 258 0.020
cellular protein modification process GO:0006464 438 0.020
single organism intracellular transport GO:1902582 207 0.019
protein import into nucleus GO:0006606 51 0.019
response to other organism GO:0051707 293 0.019
eye development GO:0001654 323 0.019
single organism nuclear import GO:1902593 51 0.018
negative regulation of developmental process GO:0051093 201 0.018
nucleobase containing compound catabolic process GO:0034655 165 0.018
cellular nitrogen compound catabolic process GO:0044270 165 0.018
regulation of cell development GO:0060284 215 0.018
chromatin remodeling GO:0006338 72 0.018
meiotic cell cycle GO:0051321 171 0.018
intracellular transport GO:0046907 228 0.018
positive regulation of phosphorus metabolic process GO:0010562 139 0.018
regulation of catalytic activity GO:0050790 185 0.018
cellular protein localization GO:0034613 160 0.017
rna 3 end processing GO:0031123 45 0.017
jak stat cascade GO:0007259 49 0.017
positive regulation of neurogenesis GO:0050769 41 0.017
regulation of nucleoside metabolic process GO:0009118 50 0.017
neurological system process GO:0050877 358 0.016
regulation of hydrolase activity GO:0051336 97 0.016
regulation of gtpase activity GO:0043087 44 0.016
cellular macromolecular complex assembly GO:0034622 153 0.016
regulation of cellular localization GO:0060341 136 0.016
cytoplasmic transport GO:0016482 130 0.016
nucleocytoplasmic transport GO:0006913 72 0.015
eye morphogenesis GO:0048592 260 0.015
defense response to other organism GO:0098542 225 0.015
g1 s transition of mitotic cell cycle GO:0000082 31 0.015
Human
nuclear transport GO:0051169 72 0.015
regulation of phosphorus metabolic process GO:0051174 210 0.015
positive regulation of molecular function GO:0044093 136 0.015
regulation of nucleotide catabolic process GO:0030811 48 0.015
response to wounding GO:0009611 94 0.015
regulation of developmental growth GO:0048638 174 0.015
acylglycerol catabolic process GO:0046464 3 0.015
organic substance transport GO:0071702 257 0.014
positive regulation of intracellular signal transduction GO:1902533 116 0.014
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.014
regulation of neuron projection development GO:0010975 69 0.014
macromolecule catabolic process GO:0009057 161 0.014
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 1 0.014
gene silencing by rna GO:0031047 57 0.014
nuclear transcribed mrna catabolic process deadenylation dependent decay GO:0000288 14 0.014
phosphorylation GO:0016310 294 0.014
positive regulation of nucleotide metabolic process GO:0045981 55 0.014
regulation of protein localization GO:0032880 76 0.014
negative regulation of transcription factor import into nucleus GO:0042992 4 0.013
posttranscriptional regulation of gene expression GO:0010608 145 0.013
positive regulation of intracellular transport GO:0032388 42 0.013
negative regulation of cell cycle GO:0045786 116 0.013
Human
regulation of phosphatase activity GO:0010921 3 0.013
cellular catabolic process GO:0044248 372 0.013
mitotic dna integrity checkpoint GO:0044774 75 0.013
Human
neuron recognition GO:0008038 101 0.013
negative regulation of cellular component organization GO:0051129 108 0.013
regulation of multicellular organismal development GO:2000026 414 0.013
positive regulation of phosphate metabolic process GO:0045937 139 0.013
positive regulation of biosynthetic process GO:0009891 316 0.012
protein complex assembly GO:0006461 200 0.012
negative regulation of transcription dna templated GO:0045892 237 0.012
positive regulation of signaling GO:0023056 243 0.012
positive regulation of gene expression GO:0010628 290 0.012
camera type eye development GO:0043010 4 0.012
regulation of localization GO:0032879 275 0.012
regulation of purine nucleotide catabolic process GO:0033121 48 0.012
stem cell development GO:0048864 79 0.011
macromolecular complex assembly GO:0065003 256 0.011
embryonic pattern specification GO:0009880 174 0.011
positive regulation of gtp catabolic process GO:0033126 43 0.011
positive regulation of nucleoside metabolic process GO:0045979 47 0.011
response to external biotic stimulus GO:0043207 293 0.011
gtp metabolic process GO:0046039 72 0.011
positive regulation of multicellular organismal process GO:0051240 143 0.011
mitotic nuclear division GO:0007067 213 0.011
sex differentiation GO:0007548 81 0.011
regulation of transcription from rna polymerase ii promoter in response to stress GO:0043618 2 0.011
innate immune response GO:0045087 144 0.011
mitochondrial membrane organization GO:0007006 3 0.010
cell proliferation GO:0008283 299 0.010
positive regulation of purine nucleotide metabolic process GO:1900544 55 0.010

RPA2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
respiratory system cancer DOID:0050615 0 0.011
cancer DOID:162 0 0.011
disease of cellular proliferation DOID:14566 0 0.011
organ system cancer DOID:0050686 0 0.011