Drosophila melanogaster

18 known processes

Hnf4 (Dmel_CG9310)

Hepatocyte nuclear factor 4

(Aliases: HNF-4(D),NR2A4,Hnf-4h,Hnf-4,HNF4alpha,dHNF4,HNF-4,DmHNF4,Dmel\CG9310,dHNF-4,CG9310,HNF4)

Hnf4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of catabolic process GO:0009894 170 0.710
cell migration GO:0016477 238 0.688
imaginal disc derived appendage morphogenesis GO:0035114 395 0.531
regulation of cell death GO:0010941 173 0.501
intracellular signal transduction GO:0035556 300 0.476
Rat
cell motility GO:0048870 251 0.458
secretion GO:0046903 109 0.447
Mouse
localization of cell GO:0051674 257 0.444
regulation of cellular component biogenesis GO:0044087 201 0.437
Rat
regulation of cellular catabolic process GO:0031329 157 0.399
organonitrogen compound metabolic process GO:1901564 318 0.384
Human
cellular catabolic process GO:0044248 372 0.371
single organism catabolic process GO:0044712 228 0.365
regulation of localization GO:0032879 275 0.364
Mouse Rat
positive regulation of cellular catabolic process GO:0031331 95 0.341
post embryonic appendage morphogenesis GO:0035120 385 0.338
response to abiotic stimulus GO:0009628 341 0.325
Fly
negative regulation of cell communication GO:0010648 223 0.313
Rat
catabolic process GO:0009056 409 0.295
nucleobase containing compound catabolic process GO:0034655 165 0.282
ameboidal type cell migration GO:0001667 151 0.279
positive regulation of catabolic process GO:0009896 105 0.278
negative regulation of signal transduction GO:0009968 206 0.253
Rat
tube development GO:0035295 244 0.246
Mouse Fly
regulation of molecular function GO:0065009 217 0.244
Rat
single organism carbohydrate metabolic process GO:0044723 72 0.230
Rat
ovarian follicle cell development GO:0030707 248 0.214
negative regulation of cellular metabolic process GO:0031324 382 0.213
Rat Fly
small gtpase mediated signal transduction GO:0007264 88 0.213
triglyceride metabolic process GO:0006641 12 0.212
chemical homeostasis GO:0048878 92 0.208
Human Mouse
homeostatic process GO:0042592 199 0.202
Human Mouse
defense response GO:0006952 300 0.200
organic substance catabolic process GO:1901575 308 0.192
cardiovascular system development GO:0072358 82 0.186
Fly
growth GO:0040007 359 0.185
Human
acylglycerol metabolic process GO:0006639 12 0.177
positive regulation of cell communication GO:0010647 250 0.176
Rat
regulation of transport GO:0051049 181 0.172
Mouse Rat
positive regulation of signaling GO:0023056 243 0.170
Rat
cellular nitrogen compound catabolic process GO:0044270 165 0.168
small molecule metabolic process GO:0044281 305 0.167
Human Rat Worm
negative regulation of response to stimulus GO:0048585 258 0.166
Rat
respiratory system development GO:0060541 213 0.165
cellular macromolecule localization GO:0070727 220 0.160
Rat
chemotaxis GO:0006935 249 0.155
epithelial cell migration GO:0010631 148 0.149
tissue migration GO:0090130 155 0.147
negative regulation of signaling GO:0023057 219 0.146
Rat
regulation of autophagy GO:0010506 62 0.146
regulation of intracellular signal transduction GO:1902531 236 0.144
Rat
purine ribonucleotide catabolic process GO:0009154 109 0.144
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.144
Human Mouse Rat Worm
negative regulation of developmental process GO:0051093 201 0.141
positive regulation of transcription dna templated GO:0045893 266 0.135
Human Mouse Rat Worm
vesicle mediated transport GO:0016192 381 0.134
Worm
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.133
purine containing compound catabolic process GO:0072523 112 0.131
cellular response to abiotic stimulus GO:0071214 58 0.131
ribonucleoside metabolic process GO:0009119 127 0.129
positive regulation of signal transduction GO:0009967 223 0.125
Rat
cell proliferation GO:0008283 299 0.123
Human Rat Fly
regulation of secretion GO:0051046 44 0.121
Mouse
pigmentation GO:0043473 75 0.120
acylglycerol catabolic process GO:0046464 3 0.120
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.119
Human Mouse Rat Worm
appendage development GO:0048736 401 0.117
aromatic compound catabolic process GO:0019439 166 0.114
central nervous system development GO:0007417 201 0.113
death GO:0016265 284 0.113
response to inorganic substance GO:0010035 44 0.112
cell death GO:0008219 279 0.112
mitotic spindle organization GO:0007052 220 0.112
glycerolipid catabolic process GO:0046503 3 0.111
glycerolipid metabolic process GO:0046486 34 0.111
positive regulation of response to stimulus GO:0048584 323 0.111
Rat
single organism behavior GO:0044708 391 0.109
purine nucleoside catabolic process GO:0006152 112 0.109
regulation of apoptotic process GO:0042981 130 0.108
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.106
Human Mouse Rat Worm
imaginal disc derived appendage development GO:0048737 399 0.105
ras protein signal transduction GO:0007265 88 0.105
wing disc morphogenesis GO:0007472 344 0.102
purine nucleotide catabolic process GO:0006195 109 0.102
negative regulation of gene expression GO:0010629 387 0.101
Fly
negative regulation of rna metabolic process GO:0051253 251 0.101
Fly
positive regulation of transport GO:0051050 92 0.101
cellular response to chemical stimulus GO:0070887 199 0.100
Human
nucleoside triphosphate catabolic process GO:0009143 108 0.100
regulation of ras gtpase activity GO:0032318 38 0.099
neurological system process GO:0050877 358 0.096
triglyceride biosynthetic process GO:0019432 2 0.096
positive regulation of macromolecule metabolic process GO:0010604 405 0.095
Human Mouse Rat Worm
epithelial cell development GO:0002064 274 0.094
regulation of ras protein signal transduction GO:0046578 93 0.094
positive regulation of catalytic activity GO:0043085 118 0.093
Rat
gtp metabolic process GO:0046039 72 0.093
neutral lipid catabolic process GO:0046461 3 0.092
taxis GO:0042330 304 0.092
Fly
positive regulation of rna biosynthetic process GO:1902680 266 0.091
Human Mouse Rat Worm
tube morphogenesis GO:0035239 191 0.090
Mouse Fly
regulation of phosphorus metabolic process GO:0051174 210 0.090
Rat
positive regulation of ras gtpase activity GO:0032320 36 0.089
connective tissue development GO:0061448 3 0.088
response to extracellular stimulus GO:0009991 116 0.088
epithelial cell differentiation GO:0030855 322 0.087
cellular lipid metabolic process GO:0044255 83 0.087
biological adhesion GO:0022610 138 0.087
protein modification process GO:0036211 438 0.087
Rat
positive regulation of biosynthetic process GO:0009891 316 0.086
Human Mouse Rat Worm
carbohydrate derivative catabolic process GO:1901136 118 0.085
ion transmembrane transport GO:0034220 122 0.085
guanosine containing compound metabolic process GO:1901068 74 0.084
oxoacid metabolic process GO:0043436 103 0.082
Human Rat Worm
developmental maturation GO:0021700 172 0.079
columnar cuboidal epithelial cell development GO:0002066 249 0.078
regulation of cellular amine metabolic process GO:0033238 3 0.078
tissue morphogenesis GO:0048729 297 0.078
Fly
carbohydrate derivative metabolic process GO:1901135 217 0.076
regulation of sequestering of triglyceride GO:0010889 3 0.075
neutral lipid metabolic process GO:0006638 12 0.074
programmed cell death GO:0012501 257 0.074
ribonucleoside triphosphate metabolic process GO:0009199 119 0.073
regulation of programmed cell death GO:0043067 152 0.073
organic cyclic compound catabolic process GO:1901361 168 0.073
ribonucleoside catabolic process GO:0042454 112 0.072
imaginal disc derived wing morphogenesis GO:0007476 337 0.072
response to hexose GO:0009746 3 0.072
Mouse Rat
protein localization GO:0008104 284 0.071
Rat
nucleotide catabolic process GO:0009166 109 0.070
response to oxygen containing compound GO:1901700 200 0.070
Mouse Rat
lipid homeostasis GO:0055088 33 0.070
Human Mouse
positive regulation of cell motility GO:2000147 3 0.070
purine ribonucleoside metabolic process GO:0046128 127 0.069
appendage morphogenesis GO:0035107 397 0.069
positive regulation of cell migration GO:0030335 2 0.068
positive regulation of phosphate metabolic process GO:0045937 139 0.068
Rat
purine ribonucleoside catabolic process GO:0046130 112 0.068
response to peptide hormone GO:0043434 29 0.068
acylglycerol biosynthetic process GO:0046463 2 0.068
positive regulation of gtpase activity GO:0043547 43 0.068
circulatory system development GO:0072359 82 0.067
Fly
apoptotic process GO:0006915 159 0.067
organic acid metabolic process GO:0006082 103 0.066
Human Rat Worm
brain development GO:0007420 120 0.066
actomyosin structure organization GO:0031032 56 0.066
neutral lipid biosynthetic process GO:0046460 2 0.066
positive regulation of nucleic acid templated transcription GO:1903508 266 0.065
Human Mouse Rat Worm
positive regulation of cellular biosynthetic process GO:0031328 316 0.064
Human Mouse Rat Worm
regulation of anatomical structure size GO:0090066 163 0.064
negative regulation of cellular biosynthetic process GO:0031327 277 0.064
Fly
locomotory behavior GO:0007626 176 0.064
cell adhesion GO:0007155 136 0.062
triglyceride catabolic process GO:0019433 3 0.062
protein transport GO:0015031 155 0.061
Rat
establishment of localization in cell GO:0051649 402 0.061
Mouse Rat
regulation of cell proliferation GO:0042127 163 0.060
Human Rat
establishment of protein localization GO:0045184 163 0.060
Rat
transcription from rna polymerase ii promoter GO:0006366 368 0.060
Human Mouse Rat Worm Fly
glycosyl compound metabolic process GO:1901657 127 0.060
learning GO:0007612 75 0.060
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.060
regulation of catalytic activity GO:0050790 185 0.059
Rat
nucleoside catabolic process GO:0009164 112 0.059
nucleoside phosphate metabolic process GO:0006753 162 0.059
telencephalon development GO:0021537 2 0.059
positive regulation of gene expression GO:0010628 290 0.059
Human Mouse Rat Worm
border follicle cell migration GO:0007298 113 0.058
negative regulation of cellular component organization GO:0051129 108 0.057
positive regulation of purine nucleotide catabolic process GO:0033123 46 0.057
heterocycle catabolic process GO:0046700 166 0.057
gtp catabolic process GO:0006184 72 0.056
positive regulation of secretion GO:0051047 22 0.056
nucleobase containing small molecule metabolic process GO:0055086 174 0.055
sterol homeostasis GO:0055092 4 0.055
Mouse
cellular response to hormone stimulus GO:0032870 44 0.055
response to oxidative stress GO:0006979 86 0.055
negative regulation of multicellular organismal process GO:0051241 142 0.054
ribonucleoside triphosphate catabolic process GO:0009203 108 0.054
positive regulation of phosphorus metabolic process GO:0010562 139 0.054
Rat
regulation of transferase activity GO:0051338 58 0.054
Rat
positive regulation of purine nucleotide metabolic process GO:1900544 55 0.053
hemopoiesis GO:0030097 46 0.053
response to radiation GO:0009314 155 0.053
Fly
organophosphate catabolic process GO:0046434 112 0.053
regulation of organelle organization GO:0033043 196 0.053
phosphorylation GO:0016310 294 0.052
Rat
head development GO:0060322 135 0.052
carbohydrate metabolic process GO:0005975 82 0.051
Rat
response to decreased oxygen levels GO:0036293 58 0.050
forebrain development GO:0030900 2 0.050
morphogenesis of an epithelium GO:0002009 276 0.050
Fly
positive regulation of gtp catabolic process GO:0033126 43 0.050
carboxylic acid metabolic process GO:0019752 92 0.049
Human Rat Worm
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.049
Human Mouse Rat Worm Fly
axon guidance GO:0007411 233 0.049
response to temperature stimulus GO:0009266 106 0.048
embryonic morphogenesis GO:0048598 206 0.048
Mouse Fly
positive regulation of nervous system development GO:0051962 69 0.048
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.048
inorganic ion transmembrane transport GO:0098660 73 0.047
immune system process GO:0002376 347 0.047
positive regulation of cellular component organization GO:0051130 156 0.047
regulation of gtp catabolic process GO:0033124 44 0.047
single organism intracellular transport GO:1902582 207 0.047
Rat
regulation of cellular localization GO:0060341 136 0.047
Mouse Rat
positive regulation of multicellular organismal process GO:0051240 143 0.046
regulation of gtpase activity GO:0043087 44 0.046
gene silencing GO:0016458 138 0.046
regulation of nucleotide catabolic process GO:0030811 48 0.046
endocytosis GO:0006897 310 0.046
Worm
negative regulation of neuron apoptotic process GO:0043524 14 0.046
associative learning GO:0008306 65 0.045
negative regulation of protein metabolic process GO:0051248 85 0.045
Rat
regulation of mapk cascade GO:0043408 92 0.044
purine nucleoside triphosphate metabolic process GO:0009144 119 0.044
ribonucleotide catabolic process GO:0009261 109 0.044
regulation of protein metabolic process GO:0051246 256 0.044
Rat
response to organic substance GO:0010033 284 0.044
Mouse Rat
cellular component assembly involved in morphogenesis GO:0010927 151 0.044
response to lipopolysaccharide GO:0032496 4 0.044
salivary gland development GO:0007431 162 0.043
endomembrane system organization GO:0010256 119 0.043
actin filament based process GO:0030029 220 0.043
response to hypoxia GO:0001666 53 0.043
epithelial tube morphogenesis GO:0060562 88 0.043
Fly
neural precursor cell proliferation GO:0061351 75 0.043
response to monosaccharide GO:0034284 4 0.043
Mouse Rat
guanosine containing compound catabolic process GO:1901069 74 0.042
stem cell proliferation GO:0072089 88 0.042
purine nucleoside triphosphate catabolic process GO:0009146 108 0.042
regulation of nucleoside metabolic process GO:0009118 50 0.041
synaptic transmission GO:0007268 288 0.041
Fly
nucleoside phosphate catabolic process GO:1901292 110 0.041
regulation of ion transport GO:0043269 39 0.041
rho protein signal transduction GO:0007266 14 0.040
somatic muscle development GO:0007525 66 0.040
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.040
Fly
regulation of cell differentiation GO:0045595 302 0.040
response to oxygen levels GO:0070482 59 0.040
neuron projection guidance GO:0097485 241 0.040
negative regulation of cell death GO:0060548 81 0.040
intracellular transport GO:0046907 228 0.039
Rat
positive regulation of developmental process GO:0051094 143 0.039
adult locomotory behavior GO:0008344 76 0.039
nucleoside metabolic process GO:0009116 127 0.039
positive regulation of immune system process GO:0002684 68 0.038
regulation of nervous system development GO:0051960 248 0.038
cellular protein modification process GO:0006464 438 0.038
Rat
adult behavior GO:0030534 137 0.038
cellular response to endogenous stimulus GO:0071495 80 0.038
aging GO:0007568 143 0.037
Worm
positive regulation of molecular function GO:0044093 136 0.037
Rat
purine ribonucleotide metabolic process GO:0009150 145 0.037
positive regulation of nucleoside metabolic process GO:0045979 47 0.037
regulation of response to stress GO:0080134 200 0.037
ovarian follicle cell migration GO:0007297 121 0.037
regulation of hydrolase activity GO:0051336 97 0.036
olfactory behavior GO:0042048 97 0.036
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.036
Human Mouse Rat Worm
positive regulation of nucleotide metabolic process GO:0045981 55 0.036
muscle cell differentiation GO:0042692 103 0.035
spindle organization GO:0007051 253 0.035
regulation of phosphorylation GO:0042325 147 0.035
Rat
positive regulation of intracellular signal transduction GO:1902533 116 0.035
Rat
response to wounding GO:0009611 94 0.035
Human
purine nucleoside metabolic process GO:0042278 127 0.035
positive regulation of hydrolase activity GO:0051345 78 0.035
anion homeostasis GO:0055081 3 0.034
Mouse
organic substance transport GO:0071702 257 0.034
Mouse Rat
macromolecular complex assembly GO:0065003 256 0.034
open tracheal system development GO:0007424 204 0.034
cell recognition GO:0008037 102 0.034
transmembrane transport GO:0055085 139 0.034
regionalization GO:0003002 416 0.034
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.034
Fly
cellular response to peptide hormone stimulus GO:0071375 28 0.034
organophosphate metabolic process GO:0019637 195 0.034
cellular protein localization GO:0034613 160 0.034
Rat
epithelium migration GO:0090132 148 0.033
purine containing compound metabolic process GO:0072521 155 0.033
stem cell differentiation GO:0048863 117 0.033
Fly
response to external biotic stimulus GO:0043207 293 0.033
single organism biosynthetic process GO:0044711 206 0.033
Rat
cellular amino acid metabolic process GO:0006520 61 0.033
Human
axonogenesis GO:0007409 290 0.033
negative regulation of growth GO:0045926 84 0.033
Human
response to peptide GO:1901652 29 0.032
cellular amine metabolic process GO:0044106 12 0.031
regulation of phosphate metabolic process GO:0019220 210 0.031
Rat
positive regulation of rna metabolic process GO:0051254 271 0.031
Human Mouse Rat Worm
synapse assembly GO:0007416 143 0.030
regulation of cellular protein metabolic process GO:0032268 243 0.030
Rat
positive regulation of nucleotide catabolic process GO:0030813 46 0.030
positive regulation of cell differentiation GO:0045597 64 0.030
regulation of cellular ketone metabolic process GO:0010565 3 0.030
Rat Worm
response to osmotic stress GO:0006970 14 0.029
stem cell development GO:0048864 79 0.029
negative regulation of transcription dna templated GO:0045892 237 0.029
Fly
response to alcohol GO:0097305 95 0.029
mitochondrion organization GO:0007005 65 0.029
negative regulation of apoptotic process GO:0043066 63 0.028
regulation of immune system process GO:0002682 176 0.028
intraspecies interaction between organisms GO:0051703 4 0.028
response to hormone GO:0009725 45 0.028
phagocytosis GO:0006909 215 0.028
monovalent inorganic cation transport GO:0015672 40 0.028
actin cytoskeleton organization GO:0030036 206 0.027
purine nucleotide metabolic process GO:0006163 146 0.027
glycoprotein biosynthetic process GO:0009101 41 0.027
glycosyl compound catabolic process GO:1901658 112 0.027
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 4 0.027
Rat
regulation of anatomical structure morphogenesis GO:0022603 242 0.026
Mouse
jak stat cascade GO:0007259 49 0.026
Rat
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.026
Fly
secretion by cell GO:0032940 101 0.026
Mouse
organelle fission GO:0048285 340 0.026
digestive system development GO:0055123 149 0.026
Mouse Fly
cellular response to dna damage stimulus GO:0006974 223 0.026
regulation of multicellular organismal development GO:2000026 414 0.026
Mouse
positive regulation of synaptic growth at neuromuscular junction GO:0045887 26 0.025
cellular response to external stimulus GO:0071496 66 0.025
imaginal disc pattern formation GO:0007447 91 0.025
determination of adult lifespan GO:0008340 137 0.025
Worm
regulation of purine nucleotide metabolic process GO:1900542 62 0.025
regulation of rho protein signal transduction GO:0035023 20 0.024
regulation of cellular component movement GO:0051270 42 0.024
hindbrain development GO:0030902 2 0.024
negative regulation of rna biosynthetic process GO:1902679 240 0.023
Fly
regulation of cell cell adhesion GO:0022407 21 0.023
nuclear division GO:0000280 332 0.023
negative regulation of molecular function GO:0044092 51 0.023
Rat
negative regulation of programmed cell death GO:0043069 72 0.023
positive regulation of lipid storage GO:0010884 4 0.023
cell junction organization GO:0034330 57 0.023
Rat
positive regulation of lipid metabolic process GO:0045834 4 0.023
Rat
meiotic cell cycle GO:0051321 171 0.023
regulation of cell adhesion GO:0030155 27 0.023
regulation of growth GO:0040008 233 0.023
Human
enzyme linked receptor protein signaling pathway GO:0007167 179 0.022
Mouse
amine metabolic process GO:0009308 12 0.022
regulation of actin filament based process GO:0032970 42 0.022
instar larval development GO:0002168 55 0.022
lipid biosynthetic process GO:0008610 46 0.022
Rat
negative regulation of biosynthetic process GO:0009890 277 0.022
Fly
positive regulation of programmed cell death GO:0043068 62 0.022
positive regulation of developmental growth GO:0048639 62 0.022
ribose phosphate metabolic process GO:0019693 145 0.022
organelle assembly GO:0070925 198 0.022
lipid modification GO:0030258 24 0.022
negative regulation of cellular protein metabolic process GO:0032269 85 0.022
Rat
maintenance of location GO:0051235 73 0.022
Worm
negative regulation of nucleic acid templated transcription GO:1903507 240 0.022
Fly
activation of protein kinase activity GO:0032147 12 0.021
Rat
inorganic cation transmembrane transport GO:0098662 61 0.021
regulation of protein kinase activity GO:0045859 51 0.021
Rat
cell projection assembly GO:0030031 94 0.021
Rat
regulation of dna metabolic process GO:0051052 34 0.021
adult walking behavior GO:0007628 9 0.021
organonitrogen compound catabolic process GO:1901565 128 0.021
cellular response to oxygen containing compound GO:1901701 79 0.021
response to nutrient levels GO:0031667 114 0.021
cellular response to peptide GO:1901653 28 0.020
cortical cytoskeleton organization GO:0030865 29 0.020
cell maturation GO:0048469 144 0.020
positive regulation of cellular component biogenesis GO:0044089 80 0.020
heart development GO:0007507 82 0.020
Fly
mapk cascade GO:0000165 107 0.020
ion transport GO:0006811 145 0.020
protein complex assembly GO:0006461 200 0.020
cellular response to carbohydrate stimulus GO:0071322 4 0.020
regulation of stress fiber assembly GO:0051492 6 0.020
regulation of defense response GO:0031347 102 0.020
negative regulation of transferase activity GO:0051348 18 0.020
regulation of developmental growth GO:0048638 174 0.020
defense response to gram negative bacterium GO:0050829 94 0.020
single organismal cell cell adhesion GO:0016337 45 0.020
regulation of multi organism process GO:0043900 131 0.020
negative regulation of intracellular signal transduction GO:1902532 57 0.020
Rat
cellular homeostasis GO:0019725 80 0.020
regulation of cell migration GO:0030334 22 0.020
regulation of cell morphogenesis GO:0022604 163 0.019
cellular response to lipopolysaccharide GO:0071222 3 0.019
regulation of immune response GO:0050776 118 0.019
cholesterol homeostasis GO:0042632 3 0.019
Mouse
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.019
Fly
cellular response to oxygen levels GO:0071453 30 0.019
single organism cellular localization GO:1902580 180 0.019
Rat
glycoprotein metabolic process GO:0009100 41 0.019
regulation of cellular response to stress GO:0080135 89 0.019
gastrulation with mouth forming first GO:0001703 36 0.019
cell type specific apoptotic process GO:0097285 38 0.019
negative regulation of organelle organization GO:0010639 56 0.019
vitamin metabolic process GO:0006766 2 0.018
cellular response to mechanical stimulus GO:0071260 2 0.018
cytoskeleton dependent intracellular transport GO:0030705 44 0.018
response to glucose GO:0009749 2 0.018
Mouse Rat
synaptic growth at neuromuscular junction GO:0051124 119 0.018
cellular ketone metabolic process GO:0042180 24 0.018
Rat Worm
positive regulation of protein modification process GO:0031401 58 0.018
Rat
regulation of small gtpase mediated signal transduction GO:0051056 93 0.018
lipid catabolic process GO:0016042 21 0.018
regulation of synapse structure and activity GO:0050803 128 0.018
metal ion transport GO:0030001 74 0.018
intracellular protein transport GO:0006886 104 0.018
Rat
regulation of cell motility GO:2000145 23 0.017
regulation of cell size GO:0008361 63 0.017
positive regulation of growth GO:0045927 75 0.017
cation transport GO:0006812 110 0.017
response to organonitrogen compound GO:0010243 75 0.017
Rat
lipid metabolic process GO:0006629 121 0.017
carbohydrate derivative biosynthetic process GO:1901137 85 0.017
chemosensory behavior GO:0007635 106 0.017
cellular response to nitrogen compound GO:1901699 51 0.017
striated muscle cell differentiation GO:0051146 90 0.017
positive regulation of cell size GO:0045793 21 0.017
leg disc development GO:0035218 92 0.017
negative regulation of neuron death GO:1901215 18 0.017
lipid localization GO:0010876 54 0.017
Worm
cellular chemical homeostasis GO:0055082 40 0.017
meiotic nuclear division GO:0007126 151 0.017
immune response GO:0006955 246 0.017
response to other organism GO:0051707 293 0.016
dna packaging GO:0006323 91 0.016
regulation of purine nucleotide catabolic process GO:0033121 48 0.016
regulation of chromosome organization GO:0033044 64 0.016
genital disc development GO:0035215 44 0.016
cellular lipid catabolic process GO:0044242 16 0.016
chromosome segregation GO:0007059 157 0.016
response to salt stress GO:0009651 11 0.016
sensory perception of mechanical stimulus GO:0050954 72 0.016
ion homeostasis GO:0050801 55 0.016
Mouse
nucleoside triphosphate metabolic process GO:0009141 120 0.016
immune system development GO:0002520 57 0.016
signal release GO:0023061 49 0.016
Mouse
membrane organization GO:0061024 112 0.016
regulation of kinase activity GO:0043549 53 0.016
Rat
cellular response to organonitrogen compound GO:0071417 36 0.016
macromolecule catabolic process GO:0009057 161 0.016
response to toxic substance GO:0009636 22 0.016
learning or memory GO:0007611 141 0.016
response to hydrogen peroxide GO:0042542 11 0.016
translation GO:0006412 69 0.015
cellular response to radiation GO:0071478 52 0.015
ethanolamine containing compound metabolic process GO:0042439 4 0.015
triglyceride homeostasis GO:0070328 18 0.015
Mouse
cellular response to oxidative stress GO:0034599 28 0.015
cell division GO:0051301 248 0.015
spermatogenesis GO:0007283 200 0.015
response to metal ion GO:0010038 23 0.015
signal transduction by phosphorylation GO:0023014 107 0.015
tor signaling GO:0031929 32 0.015
metal ion homeostasis GO:0055065 44 0.015
aggressive behavior GO:0002118 63 0.015
response to biotic stimulus GO:0009607 294 0.015
l amino acid import GO:0043092 2 0.014
ribonucleotide metabolic process GO:0009259 145 0.014
molting cycle chitin based cuticle GO:0007591 56 0.014
cell cell junction organization GO:0045216 55 0.014
Rat
regulation of actin filament bundle assembly GO:0032231 8 0.014
regulation of neuron death GO:1901214 26 0.014
response to organophosphorus GO:0046683 2 0.014
Rat
cellular response to decreased oxygen levels GO:0036294 30 0.014
rac protein signal transduction GO:0016601 3 0.014
regulation of lipid transport GO:0032368 3 0.014
negative regulation of nervous system development GO:0051961 92 0.014
regulation of stem cell proliferation GO:0072091 40 0.014
chromosome organization GO:0051276 360 0.013
dorsal ventral pattern formation GO:0009953 133 0.013
g protein coupled receptor signaling pathway GO:0007186 136 0.013
actin filament bundle assembly GO:0051017 26 0.013
single organism membrane organization GO:0044802 93 0.013
axon development GO:0061564 297 0.013
neuron recognition GO:0008038 101 0.013
nucleotide metabolic process GO:0009117 161 0.013
response to organic cyclic compound GO:0014070 89 0.013
Rat
acyl coa metabolic process GO:0006637 3 0.013
Rat
innate immune response GO:0045087 144 0.013
regulation of synaptic transmission GO:0050804 69 0.013
digestive tract morphogenesis GO:0048546 127 0.013
Mouse Fly
regulation of proteolysis GO:0030162 87 0.013
embryonic organ development GO:0048568 50 0.013
response to reactive oxygen species GO:0000302 24 0.013
regulation of actin cytoskeleton organization GO:0032956 42 0.013
response to ionizing radiation GO:0010212 32 0.013

Hnf4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.081
Human
acquired metabolic disease DOID:0060158 0 0.081
Human
disease of anatomical entity DOID:7 0 0.079
inherited metabolic disorder DOID:655 0 0.074
carbohydrate metabolism disease DOID:0050013 0 0.070
Human
glucose metabolism disease DOID:4194 0 0.053
Human
diabetes mellitus DOID:9351 0 0.045
Human
type 2 diabetes mellitus DOID:9352 0 0.045
Human
nervous system disease DOID:863 0 0.022
cancer DOID:162 0 0.018
disease of cellular proliferation DOID:14566 0 0.018
organ system cancer DOID:0050686 0 0.015