Drosophila melanogaster

36 known processes

Treh (Dmel_CG9364)

Trehalase

(Aliases: TREH,anon-EST:Posey159,Tre,CG9364,TRE,Dmel\CG9364,87D3T,anon-sts38,ESTS:87D3T)

Treh biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
axonogenesis GO:0007409 290 0.384
chemotaxis GO:0006935 249 0.370
neuron projection guidance GO:0097485 241 0.344
axon guidance GO:0007411 233 0.335
taxis GO:0042330 304 0.311
homeostatic process GO:0042592 199 0.305
axon development GO:0061564 297 0.271
organic hydroxy compound metabolic process GO:1901615 83 0.246
catabolic process GO:0009056 409 0.199
chemical homeostasis GO:0048878 92 0.194
protein modification process GO:0036211 438 0.192
detection of stimulus GO:0051606 156 0.182
cellular lipid metabolic process GO:0044255 83 0.176
carboxylic acid metabolic process GO:0019752 92 0.173
lateral inhibition GO:0046331 206 0.144
phosphorylation GO:0016310 294 0.141
cellular catabolic process GO:0044248 372 0.139
organonitrogen compound metabolic process GO:1901564 318 0.138
response to temperature stimulus GO:0009266 106 0.132
response to organic substance GO:0010033 284 0.119
cellular protein modification process GO:0006464 438 0.112
synaptic transmission GO:0007268 288 0.111
detection of light stimulus GO:0009583 58 0.106
small molecule metabolic process GO:0044281 305 0.101
oxoacid metabolic process GO:0043436 103 0.100
cellular response to chemical stimulus GO:0070887 199 0.093
organic acid metabolic process GO:0006082 103 0.091
response to abiotic stimulus GO:0009628 341 0.089
cellular homeostasis GO:0019725 80 0.085
response to oxygen containing compound GO:1901700 200 0.084
single organism intracellular transport GO:1902582 207 0.083
peptide metabolic process GO:0006518 80 0.080
phototransduction GO:0007602 52 0.080
organic substance catabolic process GO:1901575 308 0.078
cellular amino acid metabolic process GO:0006520 61 0.075
ion homeostasis GO:0050801 55 0.075
intracellular transport GO:0046907 228 0.069
transcription from rna polymerase ii promoter GO:0006366 368 0.069
proteolysis GO:0006508 192 0.069
cellular macromolecule catabolic process GO:0044265 136 0.069
neuromuscular synaptic transmission GO:0007274 67 0.067
cellular response to organic substance GO:0071310 132 0.067
body morphogenesis GO:0010171 2 0.063
endomembrane system organization GO:0010256 119 0.061
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.059
regulation of growth GO:0040008 233 0.059
organic acid catabolic process GO:0016054 16 0.056
organic substance transport GO:0071702 257 0.055
lipid metabolic process GO:0006629 121 0.052
establishment of localization in cell GO:0051649 402 0.051
tissue morphogenesis GO:0048729 297 0.048
actin cytoskeleton organization GO:0030036 206 0.048
vesicle mediated transport GO:0016192 381 0.048
intracellular signal transduction GO:0035556 300 0.047
endocytosis GO:0006897 310 0.046
intracellular ph reduction GO:0051452 7 0.045
response to bacterium GO:0009617 198 0.045
photoreceptor cell axon guidance GO:0072499 23 0.045
organonitrogen compound biosynthetic process GO:1901566 117 0.044
regulation of multicellular organismal development GO:2000026 414 0.044
protein localization GO:0008104 284 0.044
response to nutrient levels GO:0031667 114 0.043
cellular nitrogen compound catabolic process GO:0044270 165 0.041
single organism catabolic process GO:0044712 228 0.040
response to extracellular stimulus GO:0009991 116 0.040
regulation of cellular protein metabolic process GO:0032268 243 0.040
negative regulation of signaling GO:0023057 219 0.039
modification dependent macromolecule catabolic process GO:0043632 79 0.039
phagocytosis GO:0006909 215 0.037
carboxylic acid catabolic process GO:0046395 16 0.037
positive regulation of macromolecule metabolic process GO:0010604 405 0.037
positive regulation of cell communication GO:0010647 250 0.036
peptidyl amino acid modification GO:0018193 105 0.036
cell cell signaling involved in cell fate commitment GO:0045168 210 0.036
regulation of intracellular signal transduction GO:1902531 236 0.036
membrane organization GO:0061024 112 0.036
secretion GO:0046903 109 0.035
modification dependent protein catabolic process GO:0019941 78 0.034
positive regulation of cellular biosynthetic process GO:0031328 316 0.034
single organism membrane organization GO:0044802 93 0.033
regulation of microtubule cytoskeleton organization GO:0070507 41 0.033
alcohol metabolic process GO:0006066 25 0.033
detection of external stimulus GO:0009581 66 0.033
positive regulation of cellular protein metabolic process GO:0032270 118 0.032
defense response to other organism GO:0098542 225 0.032
protein transport GO:0015031 155 0.032
regulation of cellular response to stress GO:0080135 89 0.031
positive regulation of response to stimulus GO:0048584 323 0.031
regulation of response to stress GO:0080134 200 0.031
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.030
positive regulation of phosphorylation GO:0042327 87 0.030
aging GO:0007568 143 0.030
cation homeostasis GO:0055080 51 0.030
neuromuscular junction development GO:0007528 149 0.029
regulation of phosphorylation GO:0042325 147 0.029
positive regulation of rna biosynthetic process GO:1902680 266 0.028
positive regulation of transport GO:0051050 92 0.027
lipid modification GO:0030258 24 0.027
response to radiation GO:0009314 155 0.026
protein catabolic process GO:0030163 101 0.026
epithelial cell differentiation GO:0030855 322 0.026
imaginal disc derived wing morphogenesis GO:0007476 337 0.025
response to wounding GO:0009611 94 0.025
ubiquitin dependent protein catabolic process GO:0006511 78 0.025
chaeta development GO:0022416 97 0.024
regulation of molecular function GO:0065009 217 0.024
protein ubiquitination GO:0016567 70 0.024
cellular macromolecule localization GO:0070727 220 0.024
determination of adult lifespan GO:0008340 137 0.024
organelle fusion GO:0048284 46 0.024
organonitrogen compound catabolic process GO:1901565 128 0.023
small molecule catabolic process GO:0044282 21 0.023
kidney development GO:0001822 3 0.023
wing disc morphogenesis GO:0007472 344 0.023
regulation of protein metabolic process GO:0051246 256 0.023
regulation of microtubule based process GO:0032886 49 0.023
response to light stimulus GO:0009416 124 0.023
chemosensory behavior GO:0007635 106 0.023
regulation of phosphate metabolic process GO:0019220 210 0.023
negative regulation of cellular metabolic process GO:0031324 382 0.022
cellular protein catabolic process GO:0044257 83 0.022
regulation of localization GO:0032879 275 0.022
regulation of transport GO:0051049 181 0.022
single organism biosynthetic process GO:0044711 206 0.022
macromolecule catabolic process GO:0009057 161 0.022
wnt signaling pathway GO:0016055 98 0.021
protein processing GO:0016485 68 0.021
regulation of cellular component biogenesis GO:0044087 201 0.021
small molecule biosynthetic process GO:0044283 37 0.021
negative regulation of synapse assembly GO:0051964 39 0.021
regulation of establishment of planar polarity GO:0090175 22 0.021
tube morphogenesis GO:0035239 191 0.021
regulation of organelle organization GO:0033043 196 0.021
positive regulation of lipid metabolic process GO:0045834 4 0.020
proteasomal protein catabolic process GO:0010498 59 0.020
protein modification by small protein conjugation GO:0032446 79 0.020
cell junction assembly GO:0034329 42 0.020
cell migration GO:0016477 238 0.020
ras protein signal transduction GO:0007265 88 0.020
protein complex biogenesis GO:0070271 201 0.020
negative regulation of cell communication GO:0010648 223 0.020
striated muscle myosin thick filament assembly GO:0071688 3 0.019
regulation of secretion GO:0051046 44 0.019
ovarian follicle cell development GO:0030707 248 0.019
positive regulation of developmental process GO:0051094 143 0.019
rna localization GO:0006403 115 0.019
positive regulation of cell adhesion GO:0045785 10 0.019
positive regulation of catalytic activity GO:0043085 118 0.019
retina development in camera type eye GO:0060041 4 0.019
cellular chemical homeostasis GO:0055082 40 0.019
secretion by cell GO:0032940 101 0.019
posttranscriptional regulation of gene expression GO:0010608 145 0.019
negative regulation of multicellular organismal process GO:0051241 142 0.019
dna metabolic process GO:0006259 227 0.019
enzyme linked receptor protein signaling pathway GO:0007167 179 0.018
regulation of cellular amine metabolic process GO:0033238 3 0.018
cell maturation GO:0048469 144 0.018
peptidyl lysine modification GO:0018205 57 0.018
cellular ion homeostasis GO:0006873 39 0.018
cell aging GO:0007569 2 0.018
positive regulation of cellular amine metabolic process GO:0033240 0 0.018
positive regulation of gene expression GO:0010628 290 0.018
negative regulation of cellular protein metabolic process GO:0032269 85 0.018
ph reduction GO:0045851 7 0.018
regulation of notch signaling pathway GO:0008593 100 0.017
cellular cation homeostasis GO:0030003 38 0.017
imaginal disc derived appendage morphogenesis GO:0035114 395 0.017
response to insulin GO:0032868 29 0.017
regulation of synaptic transmission GO:0050804 69 0.016
forebrain development GO:0030900 2 0.016
epidermal cell differentiation GO:0009913 51 0.016
cellular response to oxygen containing compound GO:1901701 79 0.016
monocarboxylic acid metabolic process GO:0032787 29 0.016
macromolecular complex assembly GO:0065003 256 0.016
protein phosphorylation GO:0006468 169 0.016
detection of abiotic stimulus GO:0009582 66 0.016
morphogenesis of an epithelium GO:0002009 276 0.016
molting cycle GO:0042303 56 0.016
regulation of endocytosis GO:0030100 37 0.016
pigment metabolic process GO:0042440 84 0.016
regulation of cell cycle GO:0051726 291 0.016
regulation of cellular ketone metabolic process GO:0010565 3 0.016
negative regulation of cell death GO:0060548 81 0.015
neural retina development GO:0003407 4 0.015
defense response to bacterium GO:0042742 178 0.015
notch signaling pathway GO:0007219 120 0.015
epidermis development GO:0008544 65 0.015
regulation of organ morphogenesis GO:2000027 78 0.015
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 25 0.015
regulation of catalytic activity GO:0050790 185 0.015
regulation of cell proliferation GO:0042127 163 0.015
positive regulation of phosphorus metabolic process GO:0010562 139 0.015
positive regulation of transcription dna templated GO:0045893 266 0.015
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.015
regulation of mitotic cell cycle GO:0007346 190 0.015
reactive oxygen species metabolic process GO:0072593 22 0.014
actin filament based process GO:0030029 220 0.014
establishment of protein localization GO:0045184 163 0.014
hair cell differentiation GO:0035315 47 0.014
small gtpase mediated signal transduction GO:0007264 88 0.014
negative regulation of developmental process GO:0051093 201 0.014
regulation of protein modification process GO:0031399 112 0.014
regulation of protein stability GO:0031647 43 0.014
cellular response to dna damage stimulus GO:0006974 223 0.014
cellular amine metabolic process GO:0044106 12 0.014
neurological system process GO:0050877 358 0.014
regulation of mapk cascade GO:0043408 92 0.014
negative regulation of notch signaling pathway GO:0045746 41 0.014
single organism cellular localization GO:1902580 180 0.014
camera type eye development GO:0043010 4 0.013
vesicle organization GO:0016050 44 0.013
neuron recognition GO:0008038 101 0.013
glycerolipid metabolic process GO:0046486 34 0.013
regulation of cellular localization GO:0060341 136 0.013
heterocycle catabolic process GO:0046700 166 0.013
developmental growth GO:0048589 280 0.013
regulation of protein processing GO:0070613 32 0.013
mitotic cell cycle phase transition GO:0044772 138 0.013
negative regulation of phosphorus metabolic process GO:0010563 45 0.013
cytoplasmic transport GO:0016482 130 0.013
response to nitrogen compound GO:1901698 90 0.013
negative regulation of protein metabolic process GO:0051248 85 0.013
positive regulation of multicellular organismal process GO:0051240 143 0.012
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.012
positive regulation of signal transduction GO:0009967 223 0.012
regulation of mitotic cell cycle phase transition GO:1901990 130 0.012
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 38 0.012
organic cyclic compound catabolic process GO:1901361 168 0.012
epithelial cell development GO:0002064 274 0.012
negative regulation of cell proliferation GO:0008285 69 0.012
intracellular mrna localization GO:0008298 66 0.012
positive regulation of phosphate metabolic process GO:0045937 139 0.012
columnar cuboidal epithelial cell development GO:0002066 249 0.012
long chain fatty acid metabolic process GO:0001676 3 0.012
regulation of protein phosphorylation GO:0001932 64 0.012
cellular macromolecular complex assembly GO:0034622 153 0.012
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.012
regulation of wnt signaling pathway GO:0030111 68 0.012
regulation of cell differentiation GO:0045595 302 0.012
metal ion transport GO:0030001 74 0.012
larval development GO:0002164 104 0.012
oxidation reduction process GO:0055114 123 0.012
nucleobase containing compound catabolic process GO:0034655 165 0.012
regulation of cytoskeleton organization GO:0051493 89 0.012
regulation of kinase activity GO:0043549 53 0.012
cellular protein localization GO:0034613 160 0.012
internal protein amino acid acetylation GO:0006475 38 0.011
cell cycle phase transition GO:0044770 140 0.011
developmental maturation GO:0021700 172 0.011
axis specification GO:0009798 167 0.011
negative regulation of mitotic cell cycle GO:0045930 109 0.011
nucleoside phosphate metabolic process GO:0006753 162 0.011
establishment of tissue polarity GO:0007164 87 0.011
nephron development GO:0072006 3 0.011
cell growth GO:0016049 108 0.011
synaptic growth at neuromuscular junction GO:0051124 119 0.011
spindle organization GO:0007051 253 0.011
mapk cascade GO:0000165 107 0.011
cell proliferation GO:0008283 299 0.011
appendage morphogenesis GO:0035107 397 0.011
regulation of phosphorus metabolic process GO:0051174 210 0.011
response to heat GO:0009408 63 0.011
synapse organization GO:0050808 196 0.011
regulation of anatomical structure morphogenesis GO:0022603 242 0.011
organ growth GO:0035265 56 0.011
positive regulation of signaling GO:0023056 243 0.011
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.011
microtubule organizing center organization GO:0031023 168 0.011
regulation of proteolysis GO:0030162 87 0.011
protein maturation GO:0051604 71 0.011
mitotic nuclear division GO:0007067 213 0.011
negative regulation of cell cycle phase transition GO:1901988 103 0.010
positive regulation of biosynthetic process GO:0009891 316 0.010
appendage development GO:0048736 401 0.010
regulation of protein kinase activity GO:0045859 51 0.010
vesicle fusion GO:0006906 19 0.010
muscle structure development GO:0061061 224 0.010
immune effector process GO:0002252 98 0.010
chromosome organization GO:0051276 360 0.010
amine metabolic process GO:0009308 12 0.010
mitotic sister chromatid segregation GO:0000070 87 0.010
cognition GO:0050890 141 0.010
circulatory system development GO:0072359 82 0.010

Treh disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.059
nervous system disease DOID:863 0 0.043
central nervous system disease DOID:331 0 0.019
neurodegenerative disease DOID:1289 0 0.013
musculoskeletal system disease DOID:17 0 0.012
connective tissue disease DOID:65 0 0.012