Drosophila melanogaster

170 known processes

if (Dmel_CG9623)

inflated

(Aliases: alpha2Int,CT27194,alphaPS2,CG9623,alphaPS2C,PS 2,alpha[[PS2]],aPS2,Dmel\CG9623,PSalpha2,in,PS2,alpha[[PS2(ms8)]],inf,PS2alpha)

if biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
muscle attachment GO:0016203 36 0.997
motor neuron axon guidance GO:0008045 58 0.985
myofibril assembly GO:0030239 36 0.983
learning or memory GO:0007611 141 0.982
Mouse
imaginal disc derived appendage morphogenesis GO:0035114 395 0.982
cognition GO:0050890 141 0.980
Mouse
embryonic morphogenesis GO:0048598 206 0.976
Human Zebrafish Mouse Worm Fly
appendage morphogenesis GO:0035107 397 0.967
post embryonic appendage morphogenesis GO:0035120 385 0.964
border follicle cell migration GO:0007298 113 0.961
single organismal cell cell adhesion GO:0016337 45 0.961
Human Mouse
dorsal closure GO:0007391 79 0.960
Fly
hemocyte migration GO:0035099 19 0.960
biological adhesion GO:0022610 138 0.950
tube development GO:0035295 244 0.945
Human Zebrafish
cell adhesion GO:0007155 136 0.938
ameboidal type cell migration GO:0001667 151 0.924
epithelial cell migration GO:0010631 148 0.924
appendage development GO:0048736 401 0.915
cell cell adhesion mediated by integrin GO:0033631 1 0.907
Mouse
skeletal muscle organ development GO:0060538 48 0.895
imaginal disc derived wing morphogenesis GO:0007476 337 0.884
muscle organ development GO:0007517 127 0.864
actomyosin structure organization GO:0031032 56 0.863
wing disc morphogenesis GO:0007472 344 0.859
cellular component assembly involved in morphogenesis GO:0010927 151 0.846
digestive system development GO:0055123 149 0.829
Human Zebrafish
chemotaxis GO:0006935 249 0.825
establishment or maintenance of cell polarity GO:0007163 167 0.788
memory GO:0007613 94 0.778
Mouse
tube morphogenesis GO:0035239 191 0.767
Human Zebrafish
axon development GO:0061564 297 0.759
neuron projection guidance GO:0097485 241 0.753
tissue morphogenesis GO:0048729 297 0.751
Human Fly
cell migration GO:0016477 238 0.725
heterotypic cell cell adhesion GO:0034113 1 0.721
Human
substrate adhesion dependent cell spreading GO:0034446 2 0.704
Human
associative learning GO:0008306 65 0.697
extracellular structure organization GO:0043062 46 0.676
Zebrafish Mouse
negative regulation of rho protein signal transduction GO:0035024 1 0.668
mesoderm development GO:0007498 78 0.659
Human
regulation of cellular component biogenesis GO:0044087 201 0.646
axonogenesis GO:0007409 290 0.622
neuron recognition GO:0008038 101 0.620
cell proliferation GO:0008283 299 0.617
Human Zebrafish Mouse
taxis GO:0042330 304 0.607
catabolic process GO:0009056 409 0.606
Worm
malpighian tubule morphogenesis GO:0007443 44 0.601
muscle structure development GO:0061061 224 0.595
integrin mediated signaling pathway GO:0007229 3 0.595
single organism cell adhesion GO:0098602 47 0.586
Human Mouse
regulation of anatomical structure morphogenesis GO:0022603 242 0.577
localization of cell GO:0051674 257 0.566
connective tissue development GO:0061448 3 0.563
regulation of developmental growth GO:0048638 174 0.561
Fly
positive regulation of biosynthetic process GO:0009891 316 0.553
Mouse
apposition of dorsal and ventral imaginal disc derived wing surfaces GO:0007475 15 0.550
imaginal disc derived appendage development GO:0048737 399 0.542
striated muscle cell differentiation GO:0051146 90 0.536
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.525
Mouse
regulation of wnt signaling pathway GO:0030111 68 0.513
maintenance of epithelial integrity open tracheal system GO:0035160 12 0.509
wnt signaling pathway GO:0016055 98 0.505
learning GO:0007612 75 0.497
malpighian tubule development GO:0072002 64 0.496
digestive tract development GO:0048565 149 0.495
Human Zebrafish
cell motility GO:0048870 251 0.467
embryonic hemopoiesis GO:0035162 26 0.463
actin filament organization GO:0007015 126 0.453
renal tubule development GO:0061326 64 0.451
axon guidance GO:0007411 233 0.439
salivary gland morphogenesis GO:0007435 145 0.425
larval lymph gland hemopoiesis GO:0035167 17 0.422
cardiac muscle tissue development GO:0048738 9 0.410
open tracheal system development GO:0007424 204 0.405
negative regulation of multicellular organismal process GO:0051241 142 0.394
Fly
cellular response to organonitrogen compound GO:0071417 36 0.391
response to oxygen containing compound GO:1901700 200 0.390
Fly
tissue migration GO:0090130 155 0.390
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.387
Mouse
imaginal disc derived wing hair organization GO:0035317 45 0.377
larval heart development GO:0007508 6 0.373
Fly
actin cytoskeleton organization GO:0030036 206 0.372
organelle assembly GO:0070925 198 0.372
regulation of localization GO:0032879 275 0.367
Human Mouse Worm Fly
urogenital system development GO:0001655 72 0.362
Human Mouse
compound eye development GO:0048749 307 0.354
epithelium migration GO:0090132 148 0.348
cell matrix adhesion GO:0007160 6 0.345
Human Mouse
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.342
Mouse
sensory perception GO:0007600 196 0.339
striated muscle cell development GO:0055002 50 0.338
skeletal muscle fiber development GO:0048741 3 0.332
muscle cell differentiation GO:0042692 103 0.323
positive regulation of developmental growth GO:0048639 62 0.310
cellular response to nitrogen compound GO:1901699 51 0.309
ovarian follicle cell development GO:0030707 248 0.308
nephron development GO:0072006 3 0.308
neuromuscular junction development GO:0007528 149 0.307
Fly
epithelial cell differentiation GO:0030855 322 0.306
cell projection assembly GO:0030031 94 0.296
hematopoietic or lymphoid organ development GO:0048534 57 0.292
dorsal trunk growth open tracheal system GO:0035001 7 0.289
Fly
myotube cell development GO:0014904 3 0.288
organic substance catabolic process GO:1901575 308 0.286
Worm
regulation of growth GO:0040008 233 0.286
Fly
developmental growth GO:0048589 280 0.285
Fly
regulation of nervous system development GO:0051960 248 0.285
Fly
regulation of cellular localization GO:0060341 136 0.285
determination of muscle attachment site GO:0016204 7 0.280
oocyte development GO:0048599 124 0.276
Fly
immune system process GO:0002376 347 0.276
regulation of cell adhesion GO:0030155 27 0.272
Human
actin filament bundle organization GO:0061572 28 0.269
regulation of synaptic growth at neuromuscular junction GO:0008582 89 0.263
Fly
response to alcohol GO:0097305 95 0.262
Fly
morphogenesis of an epithelium GO:0002009 276 0.260
Human Fly
response to organic substance GO:0010033 284 0.250
Mouse Fly
positive regulation of cellular biosynthetic process GO:0031328 316 0.246
Mouse
regulation of epithelial cell proliferation GO:0050678 4 0.240
response to organonitrogen compound GO:0010243 75 0.240
ovarian follicle cell migration GO:0007297 121 0.231
sarcomere organization GO:0045214 26 0.220
formation of anatomical boundary GO:0048859 37 0.218
Fly
response to peptide hormone GO:0043434 29 0.218
cellular response to chemical stimulus GO:0070887 199 0.217
Mouse
negative regulation of response to stimulus GO:0048585 258 0.215
Human
positive regulation of macromolecule metabolic process GO:0010604 405 0.212
Human Mouse
embryonic development via the syncytial blastoderm GO:0001700 148 0.206
Fly
genital disc development GO:0035215 44 0.204
cellular protein modification process GO:0006464 438 0.204
Human
vesicle mediated transport GO:0016192 381 0.204
Human Mouse Worm Fly
regionalization GO:0003002 416 0.199
Zebrafish Fly
striated muscle myosin thick filament assembly GO:0071688 3 0.198
heart development GO:0007507 82 0.195
Fly
cell recognition GO:0008037 102 0.195
kidney development GO:0001822 3 0.194
Human Mouse
bmp signaling pathway GO:0030509 27 0.194
developmental growth involved in morphogenesis GO:0060560 65 0.189
Fly
regulation of multicellular organismal development GO:2000026 414 0.188
Fly
negative regulation of signaling GO:0023057 219 0.185
Human
eye development GO:0001654 323 0.182
Zebrafish
olfactory learning GO:0008355 56 0.182
response to hormone GO:0009725 45 0.182
protein phosphorylation GO:0006468 169 0.181
Human
neurological system process GO:0050877 358 0.181
hemopoiesis GO:0030097 46 0.175
establishment of ommatidial planar polarity GO:0042067 49 0.175
striated muscle tissue development GO:0014706 27 0.171
muscle tissue morphogenesis GO:0060415 2 0.169
pericardium development GO:0060039 2 0.165
Fly
anatomical structure homeostasis GO:0060249 97 0.164
enzyme linked receptor protein signaling pathway GO:0007167 179 0.163
Mouse
eye morphogenesis GO:0048592 260 0.162
Zebrafish
divalent metal ion transport GO:0070838 26 0.160
Human
renal tubule morphogenesis GO:0061333 44 0.159
negative regulation of cell communication GO:0010648 223 0.156
Human
sensory perception of sound GO:0007605 56 0.155
regulation of cell proliferation GO:0042127 163 0.152
Human Mouse
hindgut morphogenesis GO:0007442 58 0.152
columnar cuboidal epithelial cell development GO:0002066 249 0.151
mesoderm formation GO:0001707 21 0.150
Human
determination of left right symmetry GO:0007368 9 0.149
hindgut development GO:0061525 58 0.149
respiratory system development GO:0060541 213 0.147
cellular catabolic process GO:0044248 372 0.145
striated muscle adaptation GO:0014888 1 0.143
axonal defasciculation GO:0007414 12 0.143
regulation of epithelial cell migration GO:0010632 12 0.142
salivary gland development GO:0007431 162 0.139
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.138
Mouse
gland morphogenesis GO:0022612 145 0.137
single organism catabolic process GO:0044712 228 0.136
regulation of wound healing GO:0061041 13 0.135
glial cell migration GO:0008347 31 0.135
imaginal disc derived leg morphogenesis GO:0007480 80 0.130
regulation of intracellular signal transduction GO:1902531 236 0.126
membrane organization GO:0061024 112 0.126
Worm
cellular response to oxygen containing compound GO:1901701 79 0.125
muscle tissue development GO:0060537 30 0.123
Mouse
segmentation GO:0035282 207 0.123
Zebrafish
anterior malpighian tubule development GO:0061327 12 0.121
formation of primary germ layer GO:0001704 24 0.121
Human
cellular response to insulin stimulus GO:0032869 28 0.121
response to insulin GO:0032868 29 0.120
oocyte growth GO:0001555 5 0.119
Fly
regulation of canonical wnt signaling pathway GO:0060828 15 0.119
positive regulation of cell migration GO:0030335 2 0.119
Mouse
response to abiotic stimulus GO:0009628 341 0.118
regulation of cell death GO:0010941 173 0.117
Human
determination of bilateral symmetry GO:0009855 13 0.115
growth GO:0040007 359 0.114
Human Fly
compound eye morphogenesis GO:0001745 249 0.113
defense response GO:0006952 300 0.112
leg disc development GO:0035218 92 0.111
peptidyl amino acid modification GO:0018193 105 0.110
Human
determination of dorsal ventral asymmetry GO:0048262 3 0.110
regulation of cell cell adhesion GO:0022407 21 0.109
metal ion transport GO:0030001 74 0.108
Human
larval somatic muscle development GO:0007526 19 0.103
epithelial cell cell adhesion GO:0090136 6 0.102
cellular response to organic substance GO:0071310 132 0.101
Mouse
calcium ion transport GO:0006816 24 0.100
Human
gastrulation GO:0007369 70 0.100
Human Zebrafish
regulation of phosphorus metabolic process GO:0051174 210 0.100
Human
positive regulation of cell communication GO:0010647 250 0.099
Mouse
transcription from rna polymerase ii promoter GO:0006366 368 0.099
Mouse
sensory perception of chemical stimulus GO:0007606 116 0.098
muscle cell development GO:0055001 50 0.097
organonitrogen compound metabolic process GO:1901564 318 0.096
renal system development GO:0072001 72 0.095
Human Mouse
sensory perception of smell GO:0007608 80 0.095
skin development GO:0043588 65 0.095
limb development GO:0060173 1 0.094
branching morphogenesis of an epithelial tube GO:0048754 45 0.091
reproductive system development GO:0061458 74 0.091
epithelial tube morphogenesis GO:0060562 88 0.091
pericardium morphogenesis GO:0003344 2 0.091
Fly
negative regulation of synapse assembly GO:0051964 39 0.091
Fly
morphogenesis of a polarized epithelium GO:0001738 93 0.091
carboxylic acid metabolic process GO:0019752 92 0.090
response to metal ion GO:0010038 23 0.088
response to extracellular stimulus GO:0009991 116 0.087
digestive tract morphogenesis GO:0048546 127 0.086
Human Zebrafish
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.085
Mouse
regulation of phosphate metabolic process GO:0019220 210 0.085
Human
epithelial cell migration open tracheal system GO:0007427 32 0.085
response to nutrient levels GO:0031667 114 0.084
actin filament based process GO:0030029 220 0.083
torso signaling pathway GO:0008293 21 0.083
somatic muscle development GO:0007525 66 0.081
response to light stimulus GO:0009416 124 0.081
epidermis development GO:0008544 65 0.080
synaptic growth at neuromuscular junction GO:0051124 119 0.080
Fly
positive regulation of developmental process GO:0051094 143 0.080
response to transforming growth factor beta GO:0071559 18 0.080
Mouse
positive regulation of growth GO:0045927 75 0.080
regulation of cell shape GO:0008360 113 0.079
response to endogenous stimulus GO:0009719 119 0.078
Mouse
gliogenesis GO:0042063 80 0.078
purine ribonucleotide metabolic process GO:0009150 145 0.078
negative regulation of nervous system development GO:0051961 92 0.077
Fly
basement membrane organization GO:0071711 10 0.077
wound healing GO:0042060 75 0.077
Human Zebrafish Fly
regulation of catalytic activity GO:0050790 185 0.077
regulation of apoptotic process GO:0042981 130 0.076
Human
circulatory system development GO:0072359 82 0.076
Human Zebrafish Mouse Fly
cellular response to endogenous stimulus GO:0071495 80 0.075
Mouse
nucleotide metabolic process GO:0009117 161 0.075
tube formation GO:0035148 21 0.075
lymph gland development GO:0048542 28 0.074
non sensory hair organization GO:0035316 47 0.073
response to lithium ion GO:0010226 1 0.073
imaginal disc derived wing margin morphogenesis GO:0008587 41 0.073
cellular response to peptide hormone stimulus GO:0071375 28 0.073
endocytosis GO:0006897 310 0.073
Human Mouse Worm Fly
regulation of cell migration GO:0030334 22 0.072
Mouse Fly
response to nitrogen compound GO:1901698 90 0.072
aggressive behavior GO:0002118 63 0.072
hair cell differentiation GO:0035315 47 0.072
specification of symmetry GO:0009799 13 0.071
cell adhesion mediated by integrin GO:0033627 12 0.071
Mouse
anterior posterior pattern specification GO:0009952 136 0.071
Zebrafish
cellular response to transforming growth factor beta stimulus GO:0071560 18 0.071
Mouse
immune system development GO:0002520 57 0.070
positive regulation of cellular component biogenesis GO:0044089 80 0.070
ion transport GO:0006811 145 0.070
Human
regulation of system process GO:0044057 36 0.070
negative regulation of wnt signaling pathway GO:0030178 28 0.069
oxoacid metabolic process GO:0043436 103 0.069
signal transduction by phosphorylation GO:0023014 107 0.067
Mouse
response to temperature stimulus GO:0009266 106 0.067
regulation of tube architecture open tracheal system GO:0035152 68 0.067
intracellular signal transduction GO:0035556 300 0.067
Mouse
detection of stimulus GO:0051606 156 0.067
tissue homeostasis GO:0001894 36 0.067
protein catabolic process GO:0030163 101 0.067
Worm
negative regulation of signal transduction GO:0009968 206 0.066
Human
locomotory behavior GO:0007626 176 0.065
reproductive structure development GO:0048608 74 0.065
regulation of cytoskeleton organization GO:0051493 89 0.063
nucleobase containing compound catabolic process GO:0034655 165 0.063
heart process GO:0003015 37 0.063
cellular metal ion homeostasis GO:0006875 31 0.062
extrinsic apoptotic signaling pathway GO:0097191 1 0.062
Human Mouse
cellular cation homeostasis GO:0030003 38 0.062
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 6 0.061
Mouse
substrate dependent cell migration cell extension GO:0006930 3 0.061
negative regulation of cellular component organization GO:0051129 108 0.060
Fly
ceramide metabolic process GO:0006672 7 0.060
cellular response to peptide GO:1901653 28 0.059
positive regulation of catalytic activity GO:0043085 118 0.059
central nervous system development GO:0007417 201 0.058
embryonic hindgut morphogenesis GO:0048619 48 0.058
epidermal cell differentiation GO:0009913 51 0.058
visual learning GO:0008542 4 0.058
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.058
inter male aggressive behavior GO:0002121 60 0.057
response to toxic substance GO:0009636 22 0.057
gland development GO:0048732 191 0.057
substrate dependent cell migration GO:0006929 3 0.057
positive regulation of multicellular organismal process GO:0051240 143 0.057
regulation of stress fiber assembly GO:0051492 6 0.056
phagocytosis GO:0006909 215 0.056
Human Mouse Worm Fly
exocrine system development GO:0035272 162 0.056
convergent extension involved in gastrulation GO:0060027 2 0.056
establishment of tissue polarity GO:0007164 87 0.055
response to peptide GO:1901652 29 0.053
regulation of protein metabolic process GO:0051246 256 0.053
Human
lipid metabolic process GO:0006629 121 0.053
extracellular matrix organization GO:0030198 32 0.053
Zebrafish Mouse
olfactory behavior GO:0042048 97 0.053
tripartite regional subdivision GO:0007351 103 0.052
phosphorylation GO:0016310 294 0.051
Human Mouse
regulation of cell morphogenesis GO:0022604 163 0.051
positive regulation of protein localization to plasma membrane GO:1903078 3 0.050
carbohydrate derivative biosynthetic process GO:1901137 85 0.050
nucleoside phosphate catabolic process GO:1901292 110 0.050
cell cell signaling involved in cell fate commitment GO:0045168 210 0.050
regulation of heart morphogenesis GO:2000826 3 0.049
endoderm formation GO:0001706 3 0.049
Human
protein modification process GO:0036211 438 0.049
Human
cellular ketone metabolic process GO:0042180 24 0.049
erbb signaling pathway GO:0038127 58 0.049
regulation of epithelial cell migration open tracheal system GO:2000274 11 0.048
glial cell differentiation GO:0010001 35 0.048
mesoderm morphogenesis GO:0048332 22 0.048
Human
divalent inorganic cation transport GO:0072511 30 0.048
Human
cellular response to growth factor stimulus GO:0071363 30 0.047
Mouse
photoreceptor cell axon guidance GO:0072499 23 0.047
chemosensory behavior GO:0007635 106 0.047
rho protein signal transduction GO:0007266 14 0.047
cellular homeostasis GO:0019725 80 0.046
protein localization GO:0008104 284 0.046
positive regulation of protein metabolic process GO:0051247 128 0.046
Human
stress fiber assembly GO:0043149 6 0.046
organic acid metabolic process GO:0006082 103 0.046
embryonic heart tube development GO:0035050 22 0.045
regulation of cell substrate adhesion GO:0010810 2 0.045
positive regulation of molecular function GO:0044093 136 0.045
response to alkaloid GO:0043279 26 0.045
negative regulation of hormone biosynthetic process GO:0032353 1 0.045
skeletal muscle tissue development GO:0007519 13 0.045
organ growth GO:0035265 56 0.045
regulation of body fluid levels GO:0050878 14 0.044
Zebrafish
post embryonic hemopoiesis GO:0035166 17 0.043
anterior posterior pattern specification imaginal disc GO:0007448 16 0.043
regulation of behavior GO:0050795 75 0.042
negative regulation of developmental process GO:0051093 201 0.042
Human Fly
organ formation GO:0048645 39 0.041
Fly
zygotic determination of anterior posterior axis embryo GO:0007354 27 0.041
carbohydrate derivative metabolic process GO:1901135 217 0.040
response to inorganic substance GO:0010035 44 0.040
regulation of actin cytoskeleton organization GO:0032956 42 0.040
regulation of mapk cascade GO:0043408 92 0.040
haltere disc development GO:0035216 10 0.040
hemocyte development GO:0007516 7 0.040
single organism intracellular transport GO:1902582 207 0.040
regulation of apoptotic signaling pathway GO:2001233 10 0.039
Human
establishment of planar polarity GO:0001736 87 0.039
macromolecular complex assembly GO:0065003 256 0.039
regulation of reproductive process GO:2000241 54 0.039
regulation of cellular component movement GO:0051270 42 0.039
Mouse Fly
synapse assembly GO:0007416 143 0.039
Fly
endomembrane system organization GO:0010256 119 0.038
lateral inhibition GO:0046331 206 0.038
heart contraction GO:0060047 26 0.038
initiation of dorsal closure GO:0007392 12 0.038
cardiocyte differentiation GO:0035051 29 0.037
cellular amine metabolic process GO:0044106 12 0.036
regulation of organ formation GO:0003156 3 0.036
ectodermal cell differentiation GO:0010668 1 0.036
regulation of bmp signaling pathway GO:0030510 23 0.036
terminal region determination GO:0007362 25 0.036
epithelial cell development GO:0002064 274 0.035
positive regulation of phosphorus metabolic process GO:0010562 139 0.035
Human
regulation of cellular catabolic process GO:0031329 157 0.035
small molecule metabolic process GO:0044281 305 0.035
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.035
positive regulation of transcription dna templated GO:0045893 266 0.034
Mouse
regulation of neurogenesis GO:0050767 158 0.034
homeostatic process GO:0042592 199 0.034
camera type eye development GO:0043010 4 0.034
Zebrafish
death GO:0016265 284 0.034
Human Mouse
spermatogenesis GO:0007283 200 0.034
rhythmic behavior GO:0007622 76 0.033
kidney epithelium development GO:0072073 3 0.033
cellular protein complex assembly GO:0043623 71 0.033
regulation of locomotion GO:0040012 42 0.033
Human Mouse Worm Fly
regulation of programmed cell death GO:0043067 152 0.033
Human
leg disc proximal distal pattern formation GO:0007479 9 0.032
single organism biosynthetic process GO:0044711 206 0.032
purine containing compound metabolic process GO:0072521 155 0.032
filopodium assembly GO:0046847 33 0.032
blood circulation GO:0008015 26 0.031
determination of adult lifespan GO:0008340 137 0.031
outflow tract morphogenesis GO:0003151 4 0.031
germ band extension GO:0007377 11 0.030
establishment or maintenance of apical basal cell polarity GO:0035088 34 0.030
regulation of multicellular organism growth GO:0040014 40 0.030
regulation of anatomical structure size GO:0090066 163 0.029
innate immune response GO:0045087 144 0.029
development of primary sexual characteristics GO:0045137 50 0.029
renal system process GO:0003014 12 0.029
nephron morphogenesis GO:0072028 3 0.029
positive regulation of signaling GO:0023056 243 0.029
Mouse
negative regulation of cell death GO:0060548 81 0.029
Human
cell junction assembly GO:0034329 42 0.029
Mouse
regulation of actin filament bundle assembly GO:0032231 8 0.029
positive regulation of cell motility GO:2000147 3 0.029
Mouse
single organism behavior GO:0044708 391 0.028
Mouse Fly
cellular response to organic cyclic compound GO:0071407 32 0.028
single organism cellular localization GO:1902580 180 0.028
synaptic target recognition GO:0008039 45 0.028
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.028
Human
morphogenesis of embryonic epithelium GO:0016331 94 0.028
Fly
head involution GO:0008258 35 0.027
glial cell development GO:0021782 27 0.027
cardioblast differentiation GO:0010002 20 0.027
positive regulation of phosphate metabolic process GO:0045937 139 0.027
Human
positive regulation of establishment of protein localization to plasma membrane GO:0090004 3 0.027
regulation of heart contraction GO:0008016 21 0.027
regulation of phosphorylation GO:0042325 147 0.027
Human
embryo development ending in birth or egg hatching GO:0009792 152 0.027
Zebrafish Worm Fly
positive regulation of lipid metabolic process GO:0045834 4 0.027
epidermal growth factor receptor signaling pathway GO:0007173 58 0.027
calcium ion homeostasis GO:0055074 23 0.027
response to organic cyclic compound GO:0014070 89 0.026
cyclic nucleotide metabolic process GO:0009187 28 0.026
cell death GO:0008219 279 0.026
Human Mouse
hemocyte differentiation GO:0042386 38 0.026
cellular amino acid metabolic process GO:0006520 61 0.026
protein complex assembly GO:0006461 200 0.026
nephron epithelium development GO:0072009 3 0.026
positive regulation of cell cell adhesion GO:0022409 9 0.026
imaginal disc derived wing vein morphogenesis GO:0008586 44 0.025
response to radiation GO:0009314 155 0.025
cuticle development GO:0042335 86 0.025
pharynx development GO:0060465 1 0.025
cardiac cell fate determination GO:0060913 3 0.025
leg disc morphogenesis GO:0007478 80 0.025
genitalia morphogenesis GO:0035112 16 0.025
embryonic pattern specification GO:0009880 174 0.025
Zebrafish
purine nucleotide metabolic process GO:0006163 146 0.025
optokinetic behavior GO:0007634 3 0.025
cellular macromolecular complex assembly GO:0034622 153 0.025
imaginal disc derived leg segmentation GO:0036011 26 0.024
actin filament bundle assembly GO:0051017 26 0.024
gastrulation involving germ band extension GO:0010004 36 0.024
male gamete generation GO:0048232 201 0.024
multicellular organismal homeostasis GO:0048871 41 0.024
regulation of protein secretion GO:0050708 13 0.024
cellular protein localization GO:0034613 160 0.024
mesodermal cell fate specification GO:0007501 2 0.024
sex differentiation GO:0007548 81 0.024
glycosyl compound metabolic process GO:1901657 127 0.024
compound eye photoreceptor fate commitment GO:0001752 36 0.024
organic cyclic compound catabolic process GO:1901361 168 0.024
ion transmembrane transport GO:0034220 122 0.023
Human
morphogenesis of an epithelial sheet GO:0002011 6 0.023
Human Fly
cellular response to hormone stimulus GO:0032870 44 0.023
epithelial cell morphogenesis involved in gastrulation GO:0003381 7 0.023
detection of stimulus involved in sensory perception GO:0050906 92 0.023
regulation of actin filament based process GO:0032970 42 0.023
body morphogenesis GO:0010171 2 0.023
Worm
positive regulation of cell differentiation GO:0045597 64 0.023
positive regulation of response to stimulus GO:0048584 323 0.023
Mouse
larval development GO:0002164 104 0.022
Worm Fly
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 38 0.022
Mouse
muscle organ morphogenesis GO:0048644 7 0.022
dorsal ventral pattern formation GO:0009953 133 0.022
response to oxidative stress GO:0006979 86 0.022
gonadal mesoderm development GO:0007506 8 0.022
negative regulation of catalytic activity GO:0043086 42 0.022
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.022
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.022
Mouse
organic substance transport GO:0071702 257 0.022
Human

if disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.538
Human
cardiovascular system disease DOID:1287 0 0.446
musculoskeletal system disease DOID:17 0 0.207
bone development disease DOID:0080006 0 0.115
bone disease DOID:0080001 0 0.115
connective tissue disease DOID:65 0 0.115
muscular disease DOID:0080000 0 0.085
heart conduction disease DOID:10273 0 0.067
muscle tissue disease DOID:66 0 0.057
myopathy DOID:423 0 0.040
heart disease DOID:114 0 0.039
cardiomyopathy DOID:0050700 0 0.039
auditory system disease DOID:2742 0 0.037
autosomal dominant nonsyndromic deafness DOID:0050564 0 0.037
nonsyndromic deafness DOID:0050563 0 0.037
sensory system disease DOID:0050155 0 0.037
nervous system disease DOID:863 0 0.037
congenital heart disease DOID:1682 0 0.027
intrinsic cardiomyopathy DOID:0060036 0 0.025