Drosophila melanogaster

267 known processes

RhoGEF2 (Dmel_CG9635)

CG9635 gene product from transcript CG9635-RF

(Aliases: dRhoGEF2,shar,DRhoGEF,rhogef2,Rho-GEF2,RhoGEF,RhoGef2,CG9635,T2,dRhoGEF,l(2)04291,rhoGEF2,Gef2,DRhoGEF2,Dmel\CG9635,Su(Rho1)2B,DrhoGEF2)

RhoGEF2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cell motility GO:0048870 251 0.943
nuclear division GO:0000280 332 0.911
regulation of cell projection organization GO:0031344 92 0.906
appendage morphogenesis GO:0035107 397 0.889
catabolic process GO:0009056 409 0.888
regulation of anatomical structure morphogenesis GO:0022603 242 0.880
regulation of cell morphogenesis GO:0022604 163 0.852
regulation of localization GO:0032879 275 0.844
positive regulation of cellular component organization GO:0051130 156 0.829
growth GO:0040007 359 0.826
wing disc morphogenesis GO:0007472 344 0.806
epithelial cell development GO:0002064 274 0.800
regulation of developmental growth GO:0048638 174 0.689
imaginal disc derived appendage morphogenesis GO:0035114 395 0.636
tube development GO:0035295 244 0.635
establishment of localization in cell GO:0051649 402 0.628
nucleobase containing compound catabolic process GO:0034655 165 0.623
post embryonic appendage morphogenesis GO:0035120 385 0.623
regulation of protein polymerization GO:0032271 28 0.589
tube morphogenesis GO:0035239 191 0.587
protein complex biogenesis GO:0070271 201 0.577
regulation of growth GO:0040008 233 0.545
cognition GO:0050890 141 0.532
regulation of nervous system development GO:0051960 248 0.529
intracellular signal transduction GO:0035556 300 0.527
actin filament based process GO:0030029 220 0.512
regulation of multicellular organismal development GO:2000026 414 0.503
cellular catabolic process GO:0044248 372 0.483
immune system process GO:0002376 347 0.457
cellular protein modification process GO:0006464 438 0.454
heterocycle catabolic process GO:0046700 166 0.443
positive regulation of cell projection organization GO:0031346 29 0.442
imaginal disc derived appendage development GO:0048737 399 0.441
macromolecular complex assembly GO:0065003 256 0.440
regulation of phosphate metabolic process GO:0019220 210 0.424
neuron projection guidance GO:0097485 241 0.404
appendage development GO:0048736 401 0.401
imaginal disc derived wing morphogenesis GO:0007476 337 0.395
cellular component assembly involved in morphogenesis GO:0010927 151 0.392
protein catabolic process GO:0030163 101 0.387
actin cytoskeleton organization GO:0030036 206 0.384
vesicle mediated transport GO:0016192 381 0.380
regulation of axonogenesis GO:0050770 32 0.351
defense response GO:0006952 300 0.340
purine ribonucleotide catabolic process GO:0009154 109 0.334
carbohydrate derivative metabolic process GO:1901135 217 0.328
organic cyclic compound catabolic process GO:1901361 168 0.328
positive regulation of rac gtpase activity GO:0032855 8 0.321
apoptotic process GO:0006915 159 0.318
cellular macromolecule localization GO:0070727 220 0.300
cell death GO:0008219 279 0.292
cellular macromolecule catabolic process GO:0044265 136 0.290
proteolysis GO:0006508 192 0.285
regulation of cell differentiation GO:0045595 302 0.284
cellular protein localization GO:0034613 160 0.284
homeostatic process GO:0042592 199 0.272
axonogenesis GO:0007409 290 0.261
programmed cell death GO:0012501 257 0.259
developmental growth GO:0048589 280 0.259
endocytosis GO:0006897 310 0.256
positive regulation of rho gtpase activity GO:0032321 19 0.251
aromatic compound catabolic process GO:0019439 166 0.239
regulation of response to stress GO:0080134 200 0.238
organelle fission GO:0048285 340 0.237
nucleotide catabolic process GO:0009166 109 0.233
ameboidal type cell migration GO:0001667 151 0.228
protein complex assembly GO:0006461 200 0.228
ubiquitin dependent protein catabolic process GO:0006511 78 0.228
embryonic morphogenesis GO:0048598 206 0.225
cell proliferation GO:0008283 299 0.224
macromolecule catabolic process GO:0009057 161 0.223
columnar cuboidal epithelial cell development GO:0002066 249 0.222
filopodium assembly GO:0046847 33 0.217
cell division GO:0051301 248 0.210
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.208
protein modification process GO:0036211 438 0.205
positive regulation of response to stimulus GO:0048584 323 0.200
eye development GO:0001654 323 0.199
response to extracellular stimulus GO:0009991 116 0.197
cell migration GO:0016477 238 0.193
positive regulation of gtpase activity GO:0043547 43 0.190
positive regulation of transport GO:0051050 92 0.182
ribonucleoside triphosphate metabolic process GO:0009199 119 0.182
localization of cell GO:0051674 257 0.180
small molecule metabolic process GO:0044281 305 0.175
death GO:0016265 284 0.171
glycosyl compound metabolic process GO:1901657 127 0.171
digestive tract morphogenesis GO:0048546 127 0.169
regulation of vesicle mediated transport GO:0060627 59 0.169
regulation of catabolic process GO:0009894 170 0.168
nucleoside catabolic process GO:0009164 112 0.168
compound eye development GO:0048749 307 0.166
cellular protein catabolic process GO:0044257 83 0.162
epithelial cell differentiation GO:0030855 322 0.161
spindle organization GO:0007051 253 0.160
guanosine containing compound metabolic process GO:1901068 74 0.156
purine nucleotide metabolic process GO:0006163 146 0.152
purine containing compound catabolic process GO:0072523 112 0.150
regulation of rho protein signal transduction GO:0035023 20 0.148
regulation of neuron differentiation GO:0045664 103 0.146
purine nucleoside metabolic process GO:0042278 127 0.145
meiotic nuclear division GO:0007126 151 0.145
endomembrane system organization GO:0010256 119 0.144
purine nucleoside catabolic process GO:0006152 112 0.142
synapse organization GO:0050808 196 0.139
organic substance catabolic process GO:1901575 308 0.138
intracellular transport GO:0046907 228 0.138
regulation of neurogenesis GO:0050767 158 0.136
small gtpase mediated signal transduction GO:0007264 88 0.135
spindle assembly GO:0051225 80 0.132
lipid metabolic process GO:0006629 121 0.132
regulation of molecular function GO:0065009 217 0.131
taxis GO:0042330 304 0.131
positive regulation of cellular catabolic process GO:0031331 95 0.130
ribonucleoside triphosphate catabolic process GO:0009203 108 0.129
cell type specific apoptotic process GO:0097285 38 0.129
regulation of synapse organization GO:0050807 110 0.128
regulation of transport GO:0051049 181 0.128
embryonic development via the syncytial blastoderm GO:0001700 148 0.125
mitotic nuclear division GO:0007067 213 0.122
learning or memory GO:0007611 141 0.121
regulation of response to external stimulus GO:0032101 115 0.121
cell junction organization GO:0034330 57 0.120
positive regulation of developmental process GO:0051094 143 0.116
regulation of neuron projection development GO:0010975 69 0.115
protein modification by small protein conjugation or removal GO:0070647 106 0.114
organonitrogen compound metabolic process GO:1901564 318 0.113
guanosine containing compound catabolic process GO:1901069 74 0.112
neurological system process GO:0050877 358 0.111
Worm
positive regulation of cellular component biogenesis GO:0044089 80 0.111
cellular nitrogen compound catabolic process GO:0044270 165 0.110
regulation of cell development GO:0060284 215 0.110
cellular response to radiation GO:0071478 52 0.109
regulation of cell shape GO:0008360 113 0.109
chemotaxis GO:0006935 249 0.108
organophosphate metabolic process GO:0019637 195 0.107
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.105
modification dependent macromolecule catabolic process GO:0043632 79 0.105
intracellular protein transport GO:0006886 104 0.103
purine nucleoside triphosphate metabolic process GO:0009144 119 0.101
ion transport GO:0006811 145 0.100
body morphogenesis GO:0010171 2 0.099
cellular protein complex disassembly GO:0043624 35 0.097
negative regulation of nervous system development GO:0051961 92 0.097
negative regulation of response to stimulus GO:0048585 258 0.097
cytoplasmic transport GO:0016482 130 0.096
single organism behavior GO:0044708 391 0.093
Worm
regulation of cellular component movement GO:0051270 42 0.092
actin filament polymerization GO:0030041 27 0.092
developmental programmed cell death GO:0010623 138 0.091
dna metabolic process GO:0006259 227 0.087
biological adhesion GO:0022610 138 0.086
adherens junction organization GO:0034332 27 0.085
oocyte development GO:0048599 124 0.085
organic substance transport GO:0071702 257 0.084
sarcomere organization GO:0045214 26 0.084
dna repair GO:0006281 54 0.082
regulation of actin filament polymerization GO:0030833 25 0.082
protein localization to plasma membrane GO:0072659 13 0.082
apoptotic signaling pathway GO:0097190 27 0.081
maintenance of location GO:0051235 73 0.081
regulation of immune response GO:0050776 118 0.081
nucleoside triphosphate metabolic process GO:0009141 120 0.081
negative regulation of cytoskeleton organization GO:0051494 30 0.081
positive regulation of cell development GO:0010720 61 0.079
regulation of cellular protein metabolic process GO:0032268 243 0.079
positive regulation of molecular function GO:0044093 136 0.079
regulation of cell proliferation GO:0042127 163 0.079
regulation of intracellular signal transduction GO:1902531 236 0.078
protein modification by small protein conjugation GO:0032446 79 0.076
glycosyl compound catabolic process GO:1901658 112 0.076
forebrain development GO:0030900 2 0.075
morphogenesis of embryonic epithelium GO:0016331 94 0.074
cellular response to ionizing radiation GO:0071479 15 0.073
purine ribonucleotide metabolic process GO:0009150 145 0.072
regulation of cell death GO:0010941 173 0.071
dendrite development GO:0016358 204 0.069
rho protein signal transduction GO:0007266 14 0.069
positive regulation of phosphate metabolic process GO:0045937 139 0.069
reproductive structure development GO:0048608 74 0.066
cell projection assembly GO:0030031 94 0.065
negative regulation of signal transduction GO:0009968 206 0.065
dephosphorylation GO:0016311 51 0.065
axon development GO:0061564 297 0.065
positive regulation of catabolic process GO:0009896 105 0.064
positive regulation of cellular protein metabolic process GO:0032270 118 0.063
purine nucleotide catabolic process GO:0006195 109 0.063
meiotic cell cycle GO:0051321 171 0.062
digestive system development GO:0055123 149 0.062
regulation of filopodium assembly GO:0051489 24 0.060
purine ribonucleoside catabolic process GO:0046130 112 0.059
protein phosphorylation GO:0006468 169 0.059
regulation of actin filament length GO:0030832 27 0.059
regulation of cellular component size GO:0032535 98 0.058
regulation of notch signaling pathway GO:0008593 100 0.058
gland morphogenesis GO:0022612 145 0.057
regulation of immune system process GO:0002682 176 0.057
cellular response to chemical stimulus GO:0070887 199 0.057
mushroom body development GO:0016319 70 0.057
cellular amino acid metabolic process GO:0006520 61 0.056
single organism intracellular transport GO:1902582 207 0.056
phosphorylation GO:0016310 294 0.055
lamellipodium organization GO:0097581 21 0.055
morphogenesis of an epithelium GO:0002009 276 0.054
activation of ras gtpase activity GO:0032856 6 0.054
central nervous system development GO:0007417 201 0.053
regulation of cell substrate adhesion GO:0010810 2 0.053
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.052
regulation of cell size GO:0008361 63 0.051
regulation of actin polymerization or depolymerization GO:0008064 27 0.051
embryo development ending in birth or egg hatching GO:0009792 152 0.051
tissue morphogenesis GO:0048729 297 0.051
neuron recognition GO:0008038 101 0.050
response to organic substance GO:0010033 284 0.050
protein complex disassembly GO:0043241 36 0.050
nucleoside phosphate catabolic process GO:1901292 110 0.050
cell growth GO:0016049 108 0.049
response to wounding GO:0009611 94 0.049
regulation of organ morphogenesis GO:2000027 78 0.049
digestive tract development GO:0048565 149 0.048
positive regulation of multicellular organismal process GO:0051240 143 0.048
regulation of ras protein signal transduction GO:0046578 93 0.048
protein ubiquitination GO:0016567 70 0.047
golgi localization GO:0051645 2 0.047
phagocytosis GO:0006909 215 0.047
female meiotic division GO:0007143 70 0.046
olfactory behavior GO:0042048 97 0.046
axon guidance GO:0007411 233 0.045
cell cell junction organization GO:0045216 55 0.045
ribonucleoside metabolic process GO:0009119 127 0.045
cell cell junction assembly GO:0007043 38 0.045
establishment or maintenance of cell polarity GO:0007163 167 0.045
oxoacid metabolic process GO:0043436 103 0.044
tissue migration GO:0090130 155 0.044
protein localization GO:0008104 284 0.044
delamination GO:0060232 8 0.043
head development GO:0060322 135 0.043
regulation of catalytic activity GO:0050790 185 0.043
negative regulation of cell communication GO:0010648 223 0.042
sensory perception GO:0007600 196 0.042
Worm
telencephalon development GO:0021537 2 0.042
negative regulation of signaling GO:0023057 219 0.042
regulation of phosphatidylinositol 3 kinase activity GO:0043551 2 0.042
cellular component disassembly GO:0022411 46 0.042
positive regulation of protein metabolic process GO:0051247 128 0.041
immune response GO:0006955 246 0.041
cell adhesion GO:0007155 136 0.041
single organism membrane organization GO:0044802 93 0.041
compound eye photoreceptor cell differentiation GO:0001751 140 0.040
regulation of protein metabolic process GO:0051246 256 0.040
cortical actin cytoskeleton organization GO:0030866 24 0.040
regulation of rho gtpase activity GO:0032319 20 0.039
ribonucleoside catabolic process GO:0042454 112 0.039
nuclear transcribed mrna poly a tail shortening GO:0000289 12 0.039
neural precursor cell proliferation GO:0061351 75 0.039
regulation of response to wounding GO:1903034 19 0.039
nucleoside metabolic process GO:0009116 127 0.038
single organism catabolic process GO:0044712 228 0.038
regulation of actin filament based process GO:0032970 42 0.038
Zebrafish
cell competition in a multicellular organism GO:0035212 10 0.038
post golgi vesicle mediated transport GO:0006892 11 0.038
germ band extension GO:0007377 11 0.037
stem cell division GO:0017145 69 0.037
regulation of cellular catabolic process GO:0031329 157 0.037
gastrulation GO:0007369 70 0.036
ribonucleotide metabolic process GO:0009259 145 0.035
inositol lipid mediated signaling GO:0048017 4 0.035
protein localization to membrane GO:0072657 19 0.035
regulation of actin cytoskeleton organization GO:0032956 42 0.035
Zebrafish
rubidium ion transport GO:0035826 1 0.035
synapse assembly GO:0007416 143 0.035
sensory perception of mechanical stimulus GO:0050954 72 0.034
Worm
positive regulation of apoptotic cell clearance GO:2000427 2 0.034
regulation of gtp catabolic process GO:0033124 44 0.034
proteasomal protein catabolic process GO:0010498 59 0.034
germarium derived egg chamber formation GO:0007293 101 0.033
cellular protein complex assembly GO:0043623 71 0.033
single organism cellular localization GO:1902580 180 0.033
ovarian follicle cell development GO:0030707 248 0.033
regulation of nucleoside metabolic process GO:0009118 50 0.032
regulation of phosphorus metabolic process GO:0051174 210 0.032
anatomical structure homeostasis GO:0060249 97 0.032
mapk cascade GO:0000165 107 0.032
positive regulation of gtp catabolic process GO:0033126 43 0.031
membrane organization GO:0061024 112 0.031
axon extension GO:0048675 32 0.031
eye morphogenesis GO:0048592 260 0.031
regulation of protein complex disassembly GO:0043244 29 0.031
regulation of cell matrix adhesion GO:0001952 1 0.030
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.030
regulation of programmed cell death GO:0043067 152 0.030
cellularization GO:0007349 90 0.029
mesoderm development GO:0007498 78 0.029
response to nutrient levels GO:0031667 114 0.029
regulation of nucleotide catabolic process GO:0030811 48 0.029
response to light stimulus GO:0009416 124 0.028
nucleoside triphosphate catabolic process GO:0009143 108 0.028
cellular homeostasis GO:0019725 80 0.028
negative regulation of neuron death GO:1901215 18 0.028
positive regulation of cytoskeleton organization GO:0051495 21 0.028
actin filament bundle assembly GO:0051017 26 0.028
Zebrafish
regulation of cell projection assembly GO:0060491 30 0.028
planar cell polarity pathway involved in axis elongation GO:0003402 3 0.028
signal transduction by phosphorylation GO:0023014 107 0.028
immune system development GO:0002520 57 0.028
lamellipodium assembly GO:0030032 21 0.027
positive regulation of nucleotide catabolic process GO:0030813 46 0.027
regulation of proteolysis GO:0030162 87 0.027
dendrite morphogenesis GO:0048813 199 0.027
response to abiotic stimulus GO:0009628 341 0.027
Worm
regulation of gtpase activity GO:0043087 44 0.026
modification dependent protein catabolic process GO:0019941 78 0.026
organelle localization GO:0051640 148 0.026
protein transport GO:0015031 155 0.026
cellular lipid metabolic process GO:0044255 83 0.026
ribose phosphate metabolic process GO:0019693 145 0.025
positive regulation of catalytic activity GO:0043085 118 0.025
mesoderm morphogenesis GO:0048332 22 0.025
positive regulation of cell morphogenesis involved in differentiation GO:0010770 12 0.025
phototransduction GO:0007602 52 0.025
notch signaling pathway GO:0007219 120 0.025
regulation of purine nucleotide catabolic process GO:0033121 48 0.025
innate immune response GO:0045087 144 0.025
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.024
regulation of defense response GO:0031347 102 0.024
positive regulation of cell death GO:0010942 69 0.024
morphogenesis of a polarized epithelium GO:0001738 93 0.024
jnk cascade GO:0007254 50 0.024
exocrine system development GO:0035272 162 0.024
regulation of cellular component biogenesis GO:0044087 201 0.024
epithelial cell migration GO:0010631 148 0.024
compound eye morphogenesis GO:0001745 249 0.023
organic acid metabolic process GO:0006082 103 0.023
nucleotide metabolic process GO:0009117 161 0.023
phosphatidylinositol mediated signaling GO:0048015 4 0.023
golgi vesicle transport GO:0048193 27 0.023
lipid localization GO:0010876 54 0.023
cell junction assembly GO:0034329 42 0.023
ribonucleotide catabolic process GO:0009261 109 0.022
regulation of hydrolase activity GO:0051336 97 0.022
regulation of locomotion GO:0040012 42 0.022
epithelial tube morphogenesis GO:0060562 88 0.022
positive regulation of ras gtpase activity GO:0032320 36 0.022
regulation of endocytosis GO:0030100 37 0.022
immune effector process GO:0002252 98 0.021
negative regulation of neuron apoptotic process GO:0043524 14 0.021
positive regulation of phosphorus metabolic process GO:0010562 139 0.021
regulation of stress activated protein kinase signaling cascade GO:0070302 42 0.021
negative regulation of phosphate metabolic process GO:0045936 45 0.021
negative regulation of programmed cell death GO:0043069 72 0.021
gliogenesis GO:0042063 80 0.021
neuron apoptotic process GO:0051402 17 0.020
male meiosis cytokinesis GO:0007112 26 0.020
convergent extension GO:0060026 2 0.020
zymogen activation GO:0031638 20 0.020
positive regulation of intracellular transport GO:0032388 42 0.020
neuron projection extension GO:1990138 32 0.020
negative regulation of cell development GO:0010721 62 0.020
cell cell adhesion GO:0098609 26 0.019
macromolecular complex disassembly GO:0032984 37 0.019
regulation of purine nucleotide metabolic process GO:1900542 62 0.019
positive regulation of nervous system development GO:0051962 69 0.019
negative regulation of cell death GO:0060548 81 0.019
hematopoietic progenitor cell differentiation GO:0002244 1 0.019
response to radiation GO:0009314 155 0.019
cellular response to abiotic stimulus GO:0071214 58 0.019
regulation of anatomical structure size GO:0090066 163 0.018
actin polymerization or depolymerization GO:0008154 31 0.018
regulation of jnk cascade GO:0046328 40 0.018
positive regulation of glial cell proliferation GO:0060252 5 0.018
cytokinesis GO:0000910 90 0.018
hemopoiesis GO:0030097 46 0.018
chemosensory behavior GO:0007635 106 0.018
regulation of cell growth GO:0001558 43 0.018
regulation of organelle organization GO:0033043 196 0.018
Zebrafish
carboxylic acid metabolic process GO:0019752 92 0.018
organophosphate catabolic process GO:0046434 112 0.017
carbohydrate derivative catabolic process GO:1901136 118 0.017
actin filament organization GO:0007015 126 0.017
positive regulation of nucleoside metabolic process GO:0045979 47 0.017
cellular response to dna damage stimulus GO:0006974 223 0.017
regulation of apoptotic process GO:0042981 130 0.017
positive regulation of organelle organization GO:0010638 65 0.017
molting cycle GO:0042303 56 0.016
regulation of small gtpase mediated signal transduction GO:0051056 93 0.016
cellular response to organic substance GO:0071310 132 0.016
germarium derived oocyte fate determination GO:0007294 26 0.016
response to endogenous stimulus GO:0009719 119 0.016
positive regulation of endocytosis GO:0045807 22 0.016
eye photoreceptor cell development GO:0042462 81 0.016
regulation of cell junction assembly GO:1901888 2 0.016
multi organism behavior GO:0051705 175 0.016
Worm
pole plasm oskar mrna localization GO:0045451 46 0.016
regulation of cytoskeleton organization GO:0051493 89 0.016
Zebrafish
embryonic pattern specification GO:0009880 174 0.016
female germline ring canal formation GO:0007301 9 0.016
cytoskeleton dependent cytokinesis GO:0061640 81 0.015
cell substrate adhesion GO:0031589 10 0.015
nucleus organization GO:0006997 45 0.015
actomyosin structure organization GO:0031032 56 0.015
Zebrafish
regulation of microtubule depolymerization GO:0031114 24 0.015
jak stat cascade GO:0007259 49 0.015
positive regulation of hydrolase activity GO:0051345 78 0.015
long term memory GO:0007616 62 0.015
sensory organ morphogenesis GO:0090596 260 0.015
protein localization to nucleus GO:0034504 55 0.015
negative regulation of intracellular signal transduction GO:1902532 57 0.014
gland development GO:0048732 191 0.014
developmental cell growth GO:0048588 52 0.014
chemical homeostasis GO:0048878 92 0.014
cell recognition GO:0008037 102 0.014
gtp catabolic process GO:0006184 72 0.014
larval development GO:0002164 104 0.014
positive regulation of growth GO:0045927 75 0.014
cellular macromolecular complex assembly GO:0034622 153 0.014
protein polyubiquitination GO:0000209 11 0.014
rac protein signal transduction GO:0016601 3 0.014
regulation of cell cycle GO:0051726 291 0.014
plasma membrane organization GO:0007009 26 0.014
synaptic transmission GO:0007268 288 0.014
salivary gland development GO:0007431 162 0.014
ribosomal large subunit biogenesis GO:0042273 1 0.014
anterior posterior pattern specification GO:0009952 136 0.014
reproductive system development GO:0061458 74 0.013
response to ionizing radiation GO:0010212 32 0.013
dorsal ventral axon guidance GO:0033563 2 0.013
germarium derived female germ line cyst formation GO:0030727 42 0.013
leg disc morphogenesis GO:0007478 80 0.013
developmental maturation GO:0021700 172 0.013
organonitrogen compound catabolic process GO:1901565 128 0.013
negative regulation of phosphatase activity GO:0010923 3 0.013
negative regulation of apoptotic process GO:0043066 63 0.013
positive regulation of protein kinase activity GO:0045860 25 0.013
regulation of glial cell differentiation GO:0045685 1 0.013
regulation of synapse assembly GO:0051963 94 0.013
rna processing GO:0006396 147 0.013
regulation of cell motility GO:2000145 23 0.013
adult somatic muscle development GO:0007527 14 0.013
regulation of phosphorylation GO:0042325 147 0.012
immune response activating signal transduction GO:0002757 2 0.012
ras protein signal transduction GO:0007265 88 0.012
respiratory system development GO:0060541 213 0.012
cation transport GO:0006812 110 0.012
mitochondrial membrane organization GO:0007006 3 0.012
negative regulation of notch signaling pathway GO:0045746 41 0.012
maintenance of protein location in cell GO:0032507 26 0.012
positive regulation of cell differentiation GO:0045597 64 0.012
negative regulation of protein depolymerization GO:1901880 23 0.012
positive regulation of purine nucleotide metabolic process GO:1900544 55 0.012
cell activation GO:0001775 9 0.012
pigmentation GO:0043473 75 0.012
protein polymerization GO:0051258 42 0.012
oocyte construction GO:0007308 112 0.012
stress fiber assembly GO:0043149 6 0.012
Zebrafish
lipid biosynthetic process GO:0008610 46 0.012
organic hydroxy compound metabolic process GO:1901615 83 0.012
positive regulation of macromolecule metabolic process GO:0010604 405 0.011
Human
transmembrane transport GO:0055085 139 0.011
blastoderm segmentation GO:0007350 159 0.011
regulation of microtubule cytoskeleton organization GO:0070507 41 0.011
protein localization to organelle GO:0033365 82 0.011
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 1 0.011
response to growth factor GO:0070848 31 0.011
positive regulation of developmental growth GO:0048639 62 0.011
stem cell development GO:0048864 79 0.011
cortical cytoskeleton organization GO:0030865 29 0.011
regulation of cell adhesion GO:0030155 27 0.011
regulation of hemocyte proliferation GO:0035206 37 0.011
actin cytoskeleton reorganization GO:0031532 22 0.011
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.010
positive regulation of nucleotide metabolic process GO:0045981 55 0.010
morphogenesis of a branching epithelium GO:0061138 45 0.010
positive regulation of apoptotic process GO:0043065 47 0.010
regulation of viral genome replication GO:0045069 4 0.010
nucleus localization GO:0051647 34 0.010

RhoGEF2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.015
Human
disease of cellular proliferation DOID:14566 0 0.015
Human
organ system cancer DOID:0050686 0 0.015
Human
disease of anatomical entity DOID:7 0 0.012