Drosophila melanogaster

42 known processes

Int6 (Dmel_CG9677)

Int6 homologue

(Aliases: BcDNA:GM01233,l(3)j9E8,eIF3-p48/INT6,Dmel\CG9677,l(3)10547,eIF-3p48/INT-6,eIF3-S6,DINT6,BcDNA.GM01233,CG9677)

Int6 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
ribosomal large subunit biogenesis GO:0042273 1 0.777
regulation of cell cycle GO:0051726 291 0.701
cell migration GO:0016477 238 0.680
sex differentiation GO:0007548 81 0.579
Worm
dna metabolic process GO:0006259 227 0.450
reproductive system development GO:0061458 74 0.419
Worm
larval development GO:0002164 104 0.405
Worm
apoptotic process GO:0006915 159 0.389
Worm
regulation of programmed cell death GO:0043067 152 0.381
cell death GO:0008219 279 0.343
Worm
programmed cell death GO:0012501 257 0.334
Worm
death GO:0016265 284 0.323
Worm
vesicle mediated transport GO:0016192 381 0.316
gonad development GO:0008406 50 0.316
Worm
cellular macromolecular complex assembly GO:0034622 153 0.312
cell cycle phase transition GO:0044770 140 0.307
translational initiation GO:0006413 11 0.297
Human
cell motility GO:0048870 251 0.296
immune system process GO:0002376 347 0.293
regulation of apoptotic process GO:0042981 130 0.278
regulation of cell death GO:0010941 173 0.278
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.244
localization of cell GO:0051674 257 0.237
positive regulation of programmed cell death GO:0043068 62 0.224
translation GO:0006412 69 0.207
Human
development of primary sexual characteristics GO:0045137 50 0.204
Worm
regulation of mitotic cell cycle GO:0007346 190 0.203
genitalia development GO:0048806 26 0.201
Worm
endocytosis GO:0006897 310 0.195
body morphogenesis GO:0010171 2 0.195
embryo development ending in birth or egg hatching GO:0009792 152 0.188
Worm
multicellular organismal aging GO:0010259 140 0.184
reproductive structure development GO:0048608 74 0.180
Worm
protein modification process GO:0036211 438 0.172
dna damage checkpoint GO:0000077 78 0.170
aging GO:0007568 143 0.146
positive regulation of gene expression GO:0010628 290 0.133
determination of adult lifespan GO:0008340 137 0.130
ribonucleoprotein complex assembly GO:0022618 23 0.128
macromolecular complex assembly GO:0065003 256 0.120
regulation of cell cycle process GO:0010564 181 0.112
positive regulation of cysteine type endopeptidase activity GO:2001056 24 0.110
proteolysis GO:0006508 192 0.108
protein deubiquitination GO:0016579 17 0.100
spindle organization GO:0007051 253 0.091
ncrna metabolic process GO:0034660 43 0.087
positive regulation of cell death GO:0010942 69 0.084
mitotic dna damage checkpoint GO:0044773 74 0.084
regulation of cell cycle phase transition GO:1901987 130 0.081
regulation of proteolysis GO:0030162 87 0.077
protein maturation GO:0051604 71 0.073
single organism intracellular transport GO:1902582 207 0.068
regulation of endopeptidase activity GO:0052548 36 0.067
positive regulation of cellular biosynthetic process GO:0031328 316 0.065
cytoplasmic translation GO:0002181 0 0.065
regulation of mitotic cell cycle phase transition GO:1901990 130 0.062
protein modification by small protein conjugation or removal GO:0070647 106 0.058
response to external biotic stimulus GO:0043207 293 0.057
response to organic substance GO:0010033 284 0.057
rrna processing GO:0006364 3 0.056
developmental growth GO:0048589 280 0.053
cellular protein localization GO:0034613 160 0.053
membrane organization GO:0061024 112 0.053
protein processing GO:0016485 68 0.052
organelle assembly GO:0070925 198 0.051
intracellular transport GO:0046907 228 0.050
positive regulation of macromolecule metabolic process GO:0010604 405 0.050
negative regulation of biosynthetic process GO:0009890 277 0.049
cell growth GO:0016049 108 0.047
organelle fission GO:0048285 340 0.046
nucleoside catabolic process GO:0009164 112 0.046
mitotic dna integrity checkpoint GO:0044774 75 0.045
growth GO:0040007 359 0.044
developmental programmed cell death GO:0010623 138 0.044
negative regulation of mitotic cell cycle GO:0045930 109 0.043
response to other organism GO:0051707 293 0.043
regulation of response to stress GO:0080134 200 0.042
purine nucleoside triphosphate metabolic process GO:0009144 119 0.041
positive regulation of apoptotic process GO:0043065 47 0.040
organonitrogen compound metabolic process GO:1901564 318 0.040
nuclear division GO:0000280 332 0.040
cellular protein modification process GO:0006464 438 0.038
establishment of localization in cell GO:0051649 402 0.038
ribonucleoprotein complex subunit organization GO:0071826 28 0.038
negative regulation of cell cycle process GO:0010948 109 0.037
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.037
regulation of phosphorus metabolic process GO:0051174 210 0.036
carbohydrate derivative metabolic process GO:1901135 217 0.036
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.035
endomembrane system organization GO:0010256 119 0.034
ribonucleoside triphosphate catabolic process GO:0009203 108 0.033
regulation of hydrolase activity GO:0051336 97 0.033
response to biotic stimulus GO:0009607 294 0.033
protein modification by small protein conjugation GO:0032446 79 0.032
negative regulation of response to stimulus GO:0048585 258 0.032
positive regulation of biosynthetic process GO:0009891 316 0.032
mitotic nuclear division GO:0007067 213 0.032
dendrite morphogenesis GO:0048813 199 0.030
mitotic spindle organization GO:0007052 220 0.030
positive regulation of peptidase activity GO:0010952 29 0.029
regulation of cell proliferation GO:0042127 163 0.029
meiotic nuclear division GO:0007126 151 0.029
mitotic cell cycle phase transition GO:0044772 138 0.028
regulation of meiosis GO:0040020 3 0.028
single organism membrane organization GO:0044802 93 0.028
positive regulation of signaling GO:0023056 243 0.027
nucleocytoplasmic transport GO:0006913 72 0.027
regulation of gene expression epigenetic GO:0040029 128 0.027
regulation of molecular function GO:0065009 217 0.027
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 25 0.026
ribonucleoprotein complex biogenesis GO:0022613 31 0.026
purine nucleoside triphosphate catabolic process GO:0009146 108 0.025
positive regulation of rna biosynthetic process GO:1902680 266 0.025
protein destabilization GO:0031648 2 0.024
chromatin modification GO:0016568 147 0.024
negative regulation of cellular metabolic process GO:0031324 382 0.024
dna repair GO:0006281 54 0.024
hematopoietic stem cell differentiation GO:0060218 1 0.023
hemopoiesis GO:0030097 46 0.023
regulation of cellular protein metabolic process GO:0032268 243 0.023
cell division GO:0051301 248 0.023
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 44 0.023
carbohydrate derivative biosynthetic process GO:1901137 85 0.023
purine ribonucleotide metabolic process GO:0009150 145 0.022
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 23 0.022
immune response GO:0006955 246 0.022
macromolecule catabolic process GO:0009057 161 0.022
Human
negative regulation of cell cycle GO:0045786 116 0.022
protein localization GO:0008104 284 0.021
phagocytosis GO:0006909 215 0.021
negative regulation of gene expression GO:0010629 387 0.021
centrosome organization GO:0051297 163 0.021
regulation of cell division GO:0051302 72 0.021
negative regulation of intracellular transport GO:0032387 9 0.021
organic substance transport GO:0071702 257 0.020
glycosyl compound metabolic process GO:1901657 127 0.020
histolysis GO:0007559 102 0.020
innate immune response GO:0045087 144 0.019
positive regulation of catalytic activity GO:0043085 118 0.019
rna processing GO:0006396 147 0.019
protein modification by small protein removal GO:0070646 28 0.019
positive regulation of hydrolase activity GO:0051345 78 0.018
neuron projection guidance GO:0097485 241 0.018
ribonucleoside metabolic process GO:0009119 127 0.018
salivary gland histolysis GO:0035070 88 0.018
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.018
guanosine containing compound catabolic process GO:1901069 74 0.018
establishment of protein localization GO:0045184 163 0.018
small molecule metabolic process GO:0044281 305 0.018
regulation of catalytic activity GO:0050790 185 0.018
regulation of cysteine type endopeptidase activity GO:2000116 27 0.018
ribonucleotide catabolic process GO:0009261 109 0.017
purine nucleoside metabolic process GO:0042278 127 0.017
positive regulation of rna metabolic process GO:0051254 271 0.017
cellular macromolecule localization GO:0070727 220 0.017
chromosome segregation GO:0007059 157 0.017
protein complex assembly GO:0006461 200 0.017
oxoacid metabolic process GO:0043436 103 0.016
protein transport GO:0015031 155 0.016
male gamete generation GO:0048232 201 0.016
single organism cellular localization GO:1902580 180 0.016
salivary gland morphogenesis GO:0007435 145 0.016
axon development GO:0061564 297 0.016
lipid localization GO:0010876 54 0.016
negative regulation of catalytic activity GO:0043086 42 0.016
purine nucleotide catabolic process GO:0006195 109 0.016
posttranscriptional regulation of gene expression GO:0010608 145 0.015
purine nucleotide metabolic process GO:0006163 146 0.015
protein catabolic process GO:0030163 101 0.015
autophagic cell death GO:0048102 83 0.014
glycosyl compound catabolic process GO:1901658 112 0.014
positive regulation of cell communication GO:0010647 250 0.014
regulation of immune system process GO:0002682 176 0.014
cytoplasmic translational initiation GO:0002183 0 0.014
muscle organ development GO:0007517 127 0.014
organic acid metabolic process GO:0006082 103 0.014
cellular amino acid metabolic process GO:0006520 61 0.014
meiotic cell cycle GO:0051321 171 0.014
ncrna processing GO:0034470 30 0.014
lipid metabolic process GO:0006629 121 0.013
exocrine system development GO:0035272 162 0.013
regulation of growth GO:0040008 233 0.013
muscle tissue development GO:0060537 30 0.013
immune system development GO:0002520 57 0.013
positive regulation of cellular protein metabolic process GO:0032270 118 0.013
defense response to bacterium GO:0042742 178 0.013
purine ribonucleoside catabolic process GO:0046130 112 0.012
positive regulation of response to stimulus GO:0048584 323 0.012
purine ribonucleoside metabolic process GO:0046128 127 0.012
negative regulation of cell cycle phase transition GO:1901988 103 0.012
gtp catabolic process GO:0006184 72 0.012
ribosome biogenesis GO:0042254 8 0.012
histone h3 k9 modification GO:0061647 12 0.012
regulation of cellular protein catabolic process GO:1903362 44 0.012
negative regulation of developmental process GO:0051093 201 0.011
mitotic g2 dna damage checkpoint GO:0007095 69 0.011
cell cycle checkpoint GO:0000075 95 0.011
eye development GO:0001654 323 0.011
regulation of developmental growth GO:0048638 174 0.011
regulation of striated muscle contraction GO:0006942 2 0.011
spindle elongation GO:0051231 83 0.011
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.011
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.011
mitotic g2 m transition checkpoint GO:0044818 70 0.011
sensory organ morphogenesis GO:0090596 260 0.011
regulation of protein metabolic process GO:0051246 256 0.011
protein dna complex subunit organization GO:0071824 86 0.011
cellular response to chemical stimulus GO:0070887 199 0.011
organophosphate metabolic process GO:0019637 195 0.011
salivary gland development GO:0007431 162 0.011
photoreceptor cell differentiation GO:0046530 170 0.010
cellular response to nutrient GO:0031670 1 0.010
cellular protein catabolic process GO:0044257 83 0.010
regulation of nuclear division GO:0051783 58 0.010
ribonucleoside catabolic process GO:0042454 112 0.010
purine containing compound metabolic process GO:0072521 155 0.010

Int6 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.014