Drosophila melanogaster

2 known processes

PGRP-SB1 (Dmel_CG9681)

CG9681 gene product from transcript CG9681-RA

(Aliases: CG9681,PGRP SB1,Dmel\CG9681,142657_at)

PGRP-SB1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
antifungal humoral response GO:0019732 12 0.793
antibacterial humoral response GO:0019731 44 0.775
Fly
defense response to gram positive bacterium GO:0050830 41 0.511
Fly
defense response to fungus GO:0050832 48 0.452
pattern recognition receptor signaling pathway GO:0002221 2 0.348
Fly
regulation of response to stress GO:0080134 200 0.327
Fly
regulation of innate immune response GO:0045088 71 0.305
Fly
regulation of immune response GO:0050776 118 0.297
Fly
humoral immune response GO:0006959 117 0.272
Fly
activation of innate immune response GO:0002218 4 0.243
Fly
positive regulation of response to stimulus GO:0048584 323 0.241
Fly
innate immune response GO:0045087 144 0.240
Fly
defense response to other organism GO:0098542 225 0.226
Fly
immune response GO:0006955 246 0.194
Fly
immune response activating signal transduction GO:0002757 2 0.187
Fly
positive regulation of immune response GO:0050778 63 0.186
Fly
regulation of defense response GO:0031347 102 0.181
Fly
antimicrobial humoral response GO:0019730 99 0.168
Fly
response to external biotic stimulus GO:0043207 293 0.164
Fly
response to fungus GO:0009620 50 0.159
immune system process GO:0002376 347 0.143
Fly
innate immune response activating signal transduction GO:0002758 2 0.134
Fly
defense response to bacterium GO:0042742 178 0.133
Fly
defense response GO:0006952 300 0.128
Fly
response to biotic stimulus GO:0009607 294 0.122
Fly
positive regulation of biosynthetic process of antibacterial peptides active against gram negative bacteria GO:0006964 12 0.112
Fly
regulation of immune system process GO:0002682 176 0.109
Fly
response to bacterium GO:0009617 198 0.103
Fly
defense response to gram negative bacterium GO:0050829 94 0.102
Fly
positive regulation of defense response GO:0031349 59 0.091
Fly
immune response regulating signaling pathway GO:0002764 2 0.089
Fly
negative regulation of response to stimulus GO:0048585 258 0.088
Fly
regulation of antimicrobial peptide biosynthetic process GO:0002805 38 0.086
Fly
positive regulation of antimicrobial peptide biosynthetic process GO:0002807 26 0.083
Fly
positive regulation of antibacterial peptide production GO:0002803 20 0.080
Fly
amide biosynthetic process GO:0043604 42 0.078
Fly
peptidoglycan catabolic process GO:0009253 3 0.071
Fly
response to other organism GO:0051707 293 0.067
Fly
antibacterial peptide biosynthetic process GO:0002780 22 0.065
Fly
carbohydrate derivative metabolic process GO:1901135 217 0.059
Fly
cellular response to molecule of bacterial origin GO:0071219 3 0.059
Fly
peptidoglycan metabolic process GO:0000270 3 0.059
Fly
positive regulation of antibacterial peptide biosynthetic process GO:0006963 20 0.059
Fly
positive regulation of cellular biosynthetic process GO:0031328 316 0.054
Fly
regulation of antibacterial peptide production GO:0002786 22 0.054
Fly
negative regulation of signaling GO:0023057 219 0.052
Fly
intracellular signal transduction GO:0035556 300 0.051
Fly
cellular response to lipopolysaccharide GO:0071222 3 0.050
Fly
negative regulation of signal transduction GO:0009968 206 0.047
Fly
antimicrobial peptide biosynthetic process GO:0002777 38 0.047
Fly
catabolic process GO:0009056 409 0.044
Fly
positive regulation of antimicrobial peptide production GO:0002225 28 0.043
Fly
regulation of defense response to bacterium GO:1900424 30 0.042
Fly
phosphorylation GO:0016310 294 0.042
Fly
peptide biosynthetic process GO:0043043 42 0.042
Fly
regulation of response to external stimulus GO:0032101 115 0.040
Fly
positive regulation of antimicrobial humoral response GO:0002760 28 0.040
Fly
gland morphogenesis GO:0022612 145 0.040
organonitrogen compound metabolic process GO:1901564 318 0.040
Fly
antibacterial peptide production GO:0002778 22 0.040
Fly
positive regulation of defense response to bacterium GO:1900426 23 0.037
Fly
antimicrobial peptide production GO:0002775 46 0.036
Fly
response to abiotic stimulus GO:0009628 341 0.036
axis specification GO:0009798 167 0.036
cellular amino acid metabolic process GO:0006520 61 0.034
regulation of antimicrobial peptide production GO:0002784 44 0.034
Fly
cellular response to biotic stimulus GO:0071216 4 0.033
Fly
regulation of biosynthetic process of antibacterial peptides active against gram negative bacteria GO:0002813 14 0.033
Fly
defense response to virus GO:0051607 23 0.031
Fly
negative regulation of cellular metabolic process GO:0031324 382 0.031
Fly
developmental programmed cell death GO:0010623 138 0.031
negative regulation of cell communication GO:0010648 223 0.030
Fly
regionalization GO:0003002 416 0.029
regulation of intracellular signal transduction GO:1902531 236 0.028
Fly
positive regulation of cell communication GO:0010647 250 0.027
organonitrogen compound catabolic process GO:1901565 128 0.027
Fly
cellular protein modification process GO:0006464 438 0.027
positive regulation of innate immune response GO:0045089 38 0.027
Fly
cell cell signaling involved in cell fate commitment GO:0045168 210 0.026
death GO:0016265 284 0.026
lateral inhibition GO:0046331 206 0.026
negative regulation of phosphorylation GO:0042326 35 0.026
Fly
regulation of multi organism process GO:0043900 131 0.025
Fly
response to organic substance GO:0010033 284 0.025
Fly
protein modification process GO:0036211 438 0.025
organonitrogen compound biosynthetic process GO:1901566 117 0.025
Fly
response to oxygen containing compound GO:1901700 200 0.024
Fly
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.024
Fly
imaginal disc derived appendage development GO:0048737 399 0.023
macromolecule catabolic process GO:0009057 161 0.023
Fly
regulation of mapk cascade GO:0043408 92 0.023
Fly
organic substance catabolic process GO:1901575 308 0.022
Fly
positive regulation of immune system process GO:0002684 68 0.021
Fly
oxoacid metabolic process GO:0043436 103 0.021
aminoglycan catabolic process GO:0006026 6 0.021
Fly
biosynthetic process of antibacterial peptides active against gram positive bacteria GO:0002815 3 0.020
Fly
dorsal ventral axis specification GO:0009950 66 0.019
dorsal ventral pattern formation GO:0009953 133 0.019
carbohydrate derivative catabolic process GO:1901136 118 0.019
Fly
response to peptidoglycan GO:0032494 2 0.019
Fly
positive regulation of signaling GO:0023056 243 0.019
regulation of cell proliferation GO:0042127 163 0.019
body morphogenesis GO:0010171 2 0.018
cellular response to oxygen containing compound GO:1901701 79 0.018
Fly
positive regulation of signal transduction GO:0009967 223 0.018
protein maturation GO:0051604 71 0.018
regulation of multicellular organismal development GO:2000026 414 0.018
response to endogenous stimulus GO:0009719 119 0.018
Fly
olfactory behavior GO:0042048 97 0.018
response to lipopolysaccharide GO:0032496 4 0.017
Fly
cellular response to chemical stimulus GO:0070887 199 0.017
Fly
negative regulation of defense response GO:0031348 35 0.017
Fly
single organism biosynthetic process GO:0044711 206 0.017
nuclear division GO:0000280 332 0.016
multicellular organismal aging GO:0010259 140 0.016
Fly
regulation of protein metabolic process GO:0051246 256 0.016
regulation of biosynthetic process of antibacterial peptides active against gram positive bacteria GO:0002816 3 0.016
Fly
regulation of response to biotic stimulus GO:0002831 63 0.016
Fly
cell death GO:0008219 279 0.016
regulation of cell differentiation GO:0045595 302 0.016
appendage development GO:0048736 401 0.016
phagocytosis GO:0006909 215 0.016
blastoderm segmentation GO:0007350 159 0.016
segmentation GO:0035282 207 0.016
jnk cascade GO:0007254 50 0.016
Fly
appendage morphogenesis GO:0035107 397 0.016
signal transduction by phosphorylation GO:0023014 107 0.015
Fly
positive regulation of biosynthetic process of antibacterial peptides active against gram positive bacteria GO:0006965 3 0.015
Fly
endocytosis GO:0006897 310 0.015
regulation of nervous system development GO:0051960 248 0.015
alpha amino acid metabolic process GO:1901605 20 0.015
regulation of phosphorylation GO:0042325 147 0.015
Fly
organic acid metabolic process GO:0006082 103 0.015
melanization defense response GO:0035006 45 0.015
Fly
response to virus GO:0009615 28 0.015
Fly
positive regulation of intracellular signal transduction GO:1902533 116 0.015
negative regulation of developmental process GO:0051093 201 0.015
lipopolysaccharide mediated signaling pathway GO:0031663 1 0.015
Fly
anatomical structure homeostasis GO:0060249 97 0.014
phenol containing compound metabolic process GO:0018958 57 0.014
Fly
negative regulation of peptidoglycan recognition protein signaling pathway GO:0061060 3 0.014
Fly
regulation of cell development GO:0060284 215 0.014
negative regulation of cellular component organization GO:0051129 108 0.014
programmed cell death GO:0012501 257 0.014
positive regulation of biosynthetic process GO:0009891 316 0.014
Fly
regulation of molecular function GO:0065009 217 0.014
regulation of cell cycle GO:0051726 291 0.014
transcription from rna polymerase ii promoter GO:0006366 368 0.014
negative regulation of cell differentiation GO:0045596 143 0.014
stress activated protein kinase signaling cascade GO:0031098 55 0.014
Fly
mitotic nuclear division GO:0007067 213 0.014
negative regulation of immune system process GO:0002683 50 0.014
Fly
embryonic pattern specification GO:0009880 174 0.013
negative regulation of intracellular signal transduction GO:1902532 57 0.013
Fly
small molecule metabolic process GO:0044281 305 0.013
regulation of antimicrobial humoral response GO:0002759 50 0.013
Fly
cell proliferation GO:0008283 299 0.013
stress activated mapk cascade GO:0051403 52 0.013
Fly
vesicle mediated transport GO:0016192 381 0.013
purine containing compound metabolic process GO:0072521 155 0.013
imaginal disc derived wing morphogenesis GO:0007476 337 0.013
post embryonic appendage morphogenesis GO:0035120 385 0.013
eye development GO:0001654 323 0.013
growth GO:0040007 359 0.012
chromosome organization GO:0051276 360 0.012
nucleobase containing small molecule metabolic process GO:0055086 174 0.012
positive regulation of gene expression GO:0010628 290 0.012
protein phosphorylation GO:0006468 169 0.012
morphogenesis of an epithelium GO:0002009 276 0.012
regulation of peptidoglycan recognition protein signaling pathway GO:0061058 4 0.012
Fly
rrna processing GO:0006364 3 0.012
negative regulation of cell development GO:0010721 62 0.012
sensory organ morphogenesis GO:0090596 260 0.012
nucleoside phosphate metabolic process GO:0006753 162 0.012
spindle organization GO:0007051 253 0.012
regulation of jnk cascade GO:0046328 40 0.012
Fly
protein processing GO:0016485 68 0.012
single organism catabolic process GO:0044712 228 0.012
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.011
positive regulation of multi organism process GO:0043902 40 0.011
Fly
intracellular transport GO:0046907 228 0.011
camera type eye development GO:0043010 4 0.011
regulation of cellular protein metabolic process GO:0032268 243 0.011
aging GO:0007568 143 0.011
Fly
regulation of cellular ketone metabolic process GO:0010565 3 0.011
negative regulation of innate immune response GO:0045824 30 0.011
Fly
forebrain development GO:0030900 2 0.011
regulation of phosphorus metabolic process GO:0051174 210 0.011
Fly
anterior posterior pattern specification GO:0009952 136 0.011
compound eye development GO:0048749 307 0.011
cellular response to organic substance GO:0071310 132 0.011
Fly
regulation of stress activated protein kinase signaling cascade GO:0070302 42 0.011
Fly
positive regulation of macromolecule metabolic process GO:0010604 405 0.011
positive regulation of phosphorus metabolic process GO:0010562 139 0.011
connective tissue development GO:0061448 3 0.011
response to organonitrogen compound GO:0010243 75 0.011
Fly
nucleoside metabolic process GO:0009116 127 0.011
regulation of anatomical structure morphogenesis GO:0022603 242 0.011
macromolecular complex assembly GO:0065003 256 0.011
developmental growth GO:0048589 280 0.011
immune effector process GO:0002252 98 0.011
Fly
single organism cell adhesion GO:0098602 47 0.011
secondary metabolic process GO:0019748 75 0.010
Fly
regulation of cell morphogenesis GO:0022604 163 0.010
positive regulation of cell migration GO:0030335 2 0.010
imaginal disc derived appendage morphogenesis GO:0035114 395 0.010
cellular macromolecule catabolic process GO:0044265 136 0.010
negative regulation of nucleic acid templated transcription GO:1903507 240 0.010
regulation of catalytic activity GO:0050790 185 0.010
tripartite regional subdivision GO:0007351 103 0.010
regulation of neurogenesis GO:0050767 158 0.010
cell adhesion GO:0007155 136 0.010

PGRP-SB1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.029
inherited metabolic disorder DOID:655 0 0.029
disease of anatomical entity DOID:7 0 0.016
nervous system disease DOID:863 0 0.011