Drosophila melanogaster

116 known processes

TSG101 (Dmel_CG9712)

tumor suppressor protein 101

(Aliases: Tsg101,tsg101,CG9712,DmTSG101,ept,dTSg101,dVps23,dTsg101,Dmel\CG9712,CG9172,vps23)

TSG101 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
respiratory system development GO:0060541 213 0.896
tissue morphogenesis GO:0048729 297 0.884
tube development GO:0035295 244 0.867
morphogenesis of an epithelium GO:0002009 276 0.789
eye development GO:0001654 323 0.735
terminal branching open tracheal system GO:0007430 17 0.647
tube morphogenesis GO:0035239 191 0.633
establishment or maintenance of cell polarity GO:0007163 167 0.584
eye morphogenesis GO:0048592 260 0.539
regulation of localization GO:0032879 275 0.486
Human
endosomal vesicle fusion GO:0034058 4 0.482
cellular macromolecule localization GO:0070727 220 0.451
Yeast
endosomal transport GO:0016197 44 0.446
Yeast Worm
female germ line cyst formation GO:0048135 42 0.419
branching involved in open tracheal system development GO:0060446 45 0.413
trachea morphogenesis GO:0060439 22 0.395
protein localization GO:0008104 284 0.391
Yeast
regulation of epidermal growth factor receptor signaling pathway GO:0042058 42 0.370
cell division GO:0051301 248 0.353
trachea development GO:0060438 29 0.339
sensory organ morphogenesis GO:0090596 260 0.333
single organism intracellular transport GO:1902582 207 0.330
Yeast Worm
endosome transport via multivesicular body sorting pathway GO:0032509 12 0.324
Worm
post embryonic appendage morphogenesis GO:0035120 385 0.321
regulation of erbb signaling pathway GO:1901184 42 0.311
positive regulation of response to stimulus GO:0048584 323 0.304
establishment of localization in cell GO:0051649 402 0.304
Human Yeast Worm
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.303
appendage development GO:0048736 401 0.290
compound eye morphogenesis GO:0001745 249 0.277
intracellular transport GO:0046907 228 0.277
Yeast Worm
guanosine containing compound catabolic process GO:1901069 74 0.270
endocytosis GO:0006897 310 0.266
Worm
protein catabolic process GO:0030163 101 0.249
Human Worm
regulation of organelle organization GO:0033043 196 0.224
organonitrogen compound metabolic process GO:1901564 318 0.221
protein modification process GO:0036211 438 0.217
Yeast
sterol homeostasis GO:0055092 4 0.214
ethanolamine containing compound metabolic process GO:0042439 4 0.212
appendage morphogenesis GO:0035107 397 0.212
wing disc morphogenesis GO:0007472 344 0.207
purine ribonucleoside catabolic process GO:0046130 112 0.205
epithelial cell differentiation GO:0030855 322 0.202
Mouse
protein ubiquitination GO:0016567 70 0.202
Yeast
modification dependent macromolecule catabolic process GO:0043632 79 0.188
Human
cytokinesis GO:0000910 90 0.186
non sensory hair organization GO:0035316 47 0.182
epidermal growth factor receptor signaling pathway GO:0007173 58 0.181
columnar cuboidal epithelial cell development GO:0002066 249 0.178
germarium derived female germ line cyst formation GO:0030727 42 0.173
single organism membrane fusion GO:0044801 42 0.170
gtp metabolic process GO:0046039 72 0.169
compound eye development GO:0048749 307 0.167
negative regulation of erbb signaling pathway GO:1901185 29 0.162
protein modification by small protein conjugation GO:0032446 79 0.162
Yeast
regulation of vesicle mediated transport GO:0060627 59 0.157
Human
embryo development ending in birth or egg hatching GO:0009792 152 0.155
Worm
cellular protein modification process GO:0006464 438 0.153
Yeast
negative regulation of response to stimulus GO:0048585 258 0.151
vesicle mediated transport GO:0016192 381 0.149
Human Mouse Worm
organelle membrane fusion GO:0090174 16 0.148
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.146
catabolic process GO:0009056 409 0.146
Human Worm
intracellular signal transduction GO:0035556 300 0.145
regulation of intracellular signal transduction GO:1902531 236 0.144
epithelial cell development GO:0002064 274 0.141
cytoplasm organization GO:0007028 64 0.141
small molecule metabolic process GO:0044281 305 0.138
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.137
Human
endosome to lysosome transport GO:0008333 7 0.135
cellular protein localization GO:0034613 160 0.135
Yeast
regulation of anatomical structure morphogenesis GO:0022603 242 0.133
small gtpase mediated signal transduction GO:0007264 88 0.132
cell proliferation GO:0008283 299 0.130
organelle fusion GO:0048284 46 0.128
cytoplasmic transport GO:0016482 130 0.128
Yeast Worm
vesicle organization GO:0016050 44 0.127
Human Mouse
negative regulation of signal transduction GO:0009968 206 0.123
ovarian follicle cell development GO:0030707 248 0.121
mitotic nuclear division GO:0007067 213 0.121
cellular protein catabolic process GO:0044257 83 0.119
Human
regulation of small gtpase mediated signal transduction GO:0051056 93 0.116
purine nucleoside metabolic process GO:0042278 127 0.116
proteolysis GO:0006508 192 0.115
Human
alcohol biosynthetic process GO:0046165 14 0.113
amine metabolic process GO:0009308 12 0.113
purine ribonucleotide catabolic process GO:0009154 109 0.112
ribonucleoside triphosphate catabolic process GO:0009203 108 0.111
open tracheal system development GO:0007424 204 0.111
regulation of ras protein signal transduction GO:0046578 93 0.111
mitotic cytokinesis GO:0000281 50 0.107
organic hydroxy compound metabolic process GO:1901615 83 0.106
negative regulation of cell communication GO:0010648 223 0.103
protein modification by small protein conjugation or removal GO:0070647 106 0.102
Yeast
purine nucleoside catabolic process GO:0006152 112 0.101
guanosine containing compound metabolic process GO:1901068 74 0.100
enzyme linked receptor protein signaling pathway GO:0007167 179 0.099
regulation of endocytosis GO:0030100 37 0.092
regulation of cellular catabolic process GO:0031329 157 0.091
regulation of microtubule based process GO:0032886 49 0.091
imaginal disc derived appendage morphogenesis GO:0035114 395 0.090
intracellular protein transport GO:0006886 104 0.090
Yeast
morphogenesis of a polarized epithelium GO:0001738 93 0.087
ras protein signal transduction GO:0007265 88 0.085
digestive system development GO:0055123 149 0.085
cell growth GO:0016049 108 0.083
Mouse
phagocytosis GO:0006909 215 0.083
morphogenesis of a branching epithelium GO:0061138 45 0.083
gtp catabolic process GO:0006184 72 0.081
head development GO:0060322 135 0.080
ubiquitin dependent protein catabolic process GO:0006511 78 0.079
Human
phosphorylation GO:0016310 294 0.078
imaginal disc derived appendage development GO:0048737 399 0.076
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.076
single organism cellular localization GO:1902580 180 0.075
Yeast
cholesterol transport GO:0030301 2 0.075
cytoskeleton dependent cytokinesis GO:0061640 81 0.075
erbb signaling pathway GO:0038127 58 0.074
membrane fusion GO:0061025 42 0.074
lysosomal transport GO:0007041 13 0.074
organic substance catabolic process GO:1901575 308 0.073
Human Worm
imaginal disc derived wing hair organization GO:0035317 45 0.071
regulation of cell death GO:0010941 173 0.070
regulation of microtubule cytoskeleton organization GO:0070507 41 0.070
cholesterol homeostasis GO:0042632 3 0.069
microtubule polymerization or depolymerization GO:0031109 39 0.069
establishment of tissue polarity GO:0007164 87 0.069
organonitrogen compound biosynthetic process GO:1901566 117 0.067
response to organic substance GO:0010033 284 0.064
cell death GO:0008219 279 0.063
regulation of nervous system development GO:0051960 248 0.062
epithelial cell migration GO:0010631 148 0.062
glycosyl compound catabolic process GO:1901658 112 0.062
ribonucleoside metabolic process GO:0009119 127 0.060
protein maturation GO:0051604 71 0.059
regulation of immune system process GO:0002682 176 0.058
regionalization GO:0003002 416 0.058
septate junction assembly GO:0019991 26 0.057
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.057
cellular nitrogen compound catabolic process GO:0044270 165 0.057
oocyte axis specification GO:0007309 108 0.056
cell junction assembly GO:0034329 42 0.056
organelle fission GO:0048285 340 0.055
positive regulation of signal transduction GO:0009967 223 0.055
organic substance transport GO:0071702 257 0.054
Yeast
response to light stimulus GO:0009416 124 0.054
negative regulation of mitotic cell cycle GO:0045930 109 0.054
positive regulation of molecular function GO:0044093 136 0.053
cellular amine metabolic process GO:0044106 12 0.053
response to copper ion GO:0046688 4 0.052
regulation of cellular localization GO:0060341 136 0.052
Human
positive regulation of cellular catabolic process GO:0031331 95 0.052
cellular macromolecule catabolic process GO:0044265 136 0.052
Human
ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway GO:0043162 8 0.052
Human
branching morphogenesis of an epithelial tube GO:0048754 45 0.052
establishment of protein localization GO:0045184 163 0.051
Yeast
response to bacterium GO:0009617 198 0.051
regulation of protein metabolic process GO:0051246 256 0.051
Yeast
nucleoside metabolic process GO:0009116 127 0.051
pole plasm oskar mrna localization GO:0045451 46 0.051
imaginal disc derived wing morphogenesis GO:0007476 337 0.051
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.051
positive regulation of cellular component organization GO:0051130 156 0.051
developmental maturation GO:0021700 172 0.050
negative regulation of signaling GO:0023057 219 0.050
cellular protein complex disassembly GO:0043624 35 0.050
nucleotide catabolic process GO:0009166 109 0.050
epithelial tube morphogenesis GO:0060562 88 0.048
establishment or maintenance of apical basal cell polarity GO:0035088 34 0.048
positive regulation of cellular amine metabolic process GO:0033240 0 0.047
positive regulation of cell communication GO:0010647 250 0.047
establishment of planar polarity GO:0001736 87 0.047
germarium derived egg chamber formation GO:0007293 101 0.047
modification dependent protein catabolic process GO:0019941 78 0.046
Human
cell maturation GO:0048469 144 0.045
membrane budding GO:0006900 4 0.044
Human Mouse
regulation of cytoskeleton organization GO:0051493 89 0.044
membrane organization GO:0061024 112 0.044
Human Yeast Mouse
microtubule depolymerization GO:0007019 25 0.044
nucleoside triphosphate metabolic process GO:0009141 120 0.043
negative regulation of intracellular signal transduction GO:1902532 57 0.042
regulation of mitotic cell cycle GO:0007346 190 0.042
ribonucleotide catabolic process GO:0009261 109 0.042
regulation of growth GO:0040008 233 0.042
organophosphate biosynthetic process GO:0090407 46 0.041
regulation of cell proliferation GO:0042127 163 0.041
Mouse
purine nucleotide catabolic process GO:0006195 109 0.040
nucleobase containing compound catabolic process GO:0034655 165 0.040
nucleoside phosphate catabolic process GO:1901292 110 0.040
purine ribonucleoside metabolic process GO:0046128 127 0.040
early endosome to late endosome transport GO:0045022 3 0.039
Worm
epithelial cell migration open tracheal system GO:0007427 32 0.039
protein localization to organelle GO:0033365 82 0.039
Yeast
regulation of epithelial cell proliferation GO:0050678 4 0.039
regulation of cell cycle process GO:0010564 181 0.039
apoptotic process GO:0006915 159 0.039
regulation of cell cycle GO:0051726 291 0.038
Mouse
lipid modification GO:0030258 24 0.038
immune response GO:0006955 246 0.038
response to other organism GO:0051707 293 0.037
endomembrane system organization GO:0010256 119 0.037
regulation of hydrolase activity GO:0051336 97 0.037
regulation of cellular component size GO:0032535 98 0.037
nucleotide metabolic process GO:0009117 161 0.036
carbohydrate derivative metabolic process GO:1901135 217 0.036
hindbrain development GO:0030902 2 0.036
autophagic vacuole fusion GO:0000046 15 0.036
negative regulation of epidermal growth factor receptor signaling pathway GO:0042059 29 0.036
regulation of molecular function GO:0065009 217 0.036
mesoderm development GO:0007498 78 0.035
cell adhesion GO:0007155 136 0.035
protein processing GO:0016485 68 0.035
body morphogenesis GO:0010171 2 0.035
regulation of erk1 and erk2 cascade GO:0070372 39 0.035
germ line cyst formation GO:0048134 44 0.034
actin filament based process GO:0030029 220 0.034
ribonucleoside catabolic process GO:0042454 112 0.034
localization of cell GO:0051674 257 0.034
positive regulation of gtpase activity GO:0043547 43 0.034
steroid metabolic process GO:0008202 20 0.033
immune system process GO:0002376 347 0.033
negative regulation of cell cycle phase transition GO:1901988 103 0.033
protein import into nucleus GO:0006606 51 0.033
macromolecular complex assembly GO:0065003 256 0.033
negative regulation of rna metabolic process GO:0051253 251 0.033
Mouse
regulation of phosphorus metabolic process GO:0051174 210 0.032
regulation of mitosis GO:0007088 56 0.032
oocyte microtubule cytoskeleton polarization GO:0008103 22 0.032
larval somatic muscle development GO:0007526 19 0.032
glycosyl compound metabolic process GO:1901657 127 0.032
purine containing compound catabolic process GO:0072523 112 0.032
sterol metabolic process GO:0016125 12 0.032
taxis GO:0042330 304 0.031
skin development GO:0043588 65 0.031
Mouse
regulation of programmed cell death GO:0043067 152 0.031
oocyte anterior posterior axis specification GO:0007314 72 0.031
regulation of phosphate metabolic process GO:0019220 210 0.031
nucleocytoplasmic transport GO:0006913 72 0.031
defense response to other organism GO:0098542 225 0.031
vesicle fusion GO:0006906 19 0.031
notch signaling pathway GO:0007219 120 0.031
phosphatidylcholine metabolic process GO:0046470 3 0.030
positive regulation of erk1 and erk2 cascade GO:0070374 36 0.030
regulation of gtpase activity GO:0043087 44 0.030
cellular response to nutrient levels GO:0031669 62 0.030
cell migration GO:0016477 238 0.029
positive regulation of ras gtpase activity GO:0032320 36 0.029
positive regulation of hydrolase activity GO:0051345 78 0.029
spermatid differentiation GO:0048515 114 0.029
protein localization to plasma membrane GO:0072659 13 0.029
cell motility GO:0048870 251 0.029
spindle assembly GO:0051225 80 0.028
negative regulation of cellular metabolic process GO:0031324 382 0.028
Yeast Mouse
regulation of cellular amino acid metabolic process GO:0006521 0 0.028
regulation of synapse assembly GO:0051963 94 0.027
digestive tract morphogenesis GO:0048546 127 0.027
protein complex biogenesis GO:0070271 201 0.027
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 4 0.027
regulation of mitochondrion organization GO:0010821 12 0.027
ribonucleoside triphosphate metabolic process GO:0009199 119 0.027
response to radiation GO:0009314 155 0.027
response to external biotic stimulus GO:0043207 293 0.027
positive regulation of rab gtpase activity GO:0032851 7 0.027
rna localization GO:0006403 115 0.027
activation of cysteine type endopeptidase activity GO:0097202 17 0.026
positive regulation of phosphorus metabolic process GO:0010562 139 0.026
cytoplasmic transport nurse cell to oocyte GO:0007303 12 0.026
anterior posterior pattern specification GO:0009952 136 0.026
intracellular mrna localization involved in pattern specification process GO:0060810 56 0.026
regulation of neuron differentiation GO:0045664 103 0.026
regulation of intracellular transport GO:0032386 64 0.026
morphogenesis of a branching structure GO:0001763 45 0.026
organophosphate metabolic process GO:0019637 195 0.026
regulation of anatomical structure size GO:0090066 163 0.026
lipid metabolic process GO:0006629 121 0.026
nuclear division GO:0000280 332 0.026
response to endogenous stimulus GO:0009719 119 0.026
cellular component disassembly GO:0022411 46 0.026
response to biotic stimulus GO:0009607 294 0.025
regulation of ras gtpase activity GO:0032318 38 0.025
single organism biosynthetic process GO:0044711 206 0.025
regulation of cellular protein metabolic process GO:0032268 243 0.025
Yeast
cellular lipid metabolic process GO:0044255 83 0.025
organelle localization GO:0051640 148 0.025
macromolecule catabolic process GO:0009057 161 0.025
Human Worm
protein targeting to nucleus GO:0044744 51 0.025
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.025
digestive tract development GO:0048565 149 0.024
regulation of proteolysis GO:0030162 87 0.024
regulation of notch signaling pathway GO:0008593 100 0.024
retrograde transport endosome to golgi GO:0042147 3 0.024
nucleoside phosphate metabolic process GO:0006753 162 0.024
regulation of catalytic activity GO:0050790 185 0.024
central nervous system development GO:0007417 201 0.024
response to extracellular stimulus GO:0009991 116 0.024
positive regulation of purine nucleotide catabolic process GO:0033123 46 0.024
eggshell formation GO:0030703 105 0.024
regulation of mapk cascade GO:0043408 92 0.023
regulation of synapse organization GO:0050807 110 0.023
regulation of catabolic process GO:0009894 170 0.023
growth GO:0040007 359 0.023
chemical homeostasis GO:0048878 92 0.023
establishment or maintenance of bipolar cell polarity GO:0061245 34 0.023
negative regulation of organelle organization GO:0010639 56 0.023
purine nucleotide metabolic process GO:0006163 146 0.023
protein depolymerization GO:0051261 31 0.023
alcohol metabolic process GO:0006066 25 0.022
ameboidal type cell migration GO:0001667 151 0.022
regulation of cellular component biogenesis GO:0044087 201 0.022
purine containing compound metabolic process GO:0072521 155 0.022
cellular response to organic substance GO:0071310 132 0.022
positive regulation of nucleic acid templated transcription GO:1903508 266 0.022
blastoderm segmentation GO:0007350 159 0.021
positive regulation of cysteine type endopeptidase activity GO:2001056 24 0.021
embryonic morphogenesis GO:0048598 206 0.021
protein transport GO:0015031 155 0.021
Yeast
tripartite regional subdivision GO:0007351 103 0.021
response to nutrient levels GO:0031667 114 0.021
lipid homeostasis GO:0055088 33 0.021
chorion containing eggshell formation GO:0007304 105 0.021
proteasomal protein catabolic process GO:0010498 59 0.021
heterocycle catabolic process GO:0046700 166 0.021
biological adhesion GO:0022610 138 0.021
regulation of cellular ketone metabolic process GO:0010565 3 0.021
reproductive system development GO:0061458 74 0.021
ovarian follicle cell migration GO:0007297 121 0.021
organic cyclic compound catabolic process GO:1901361 168 0.021
intracellular ph reduction GO:0051452 7 0.021
death GO:0016265 284 0.021
regulation of phosphorylation GO:0042325 147 0.020
cellular response to starvation GO:0009267 61 0.020
hair cell differentiation GO:0035315 47 0.020
intracellular mrna localization GO:0008298 66 0.020
chaeta development GO:0022416 97 0.020
axis specification GO:0009798 167 0.020
negative regulation of growth of symbiont involved in interaction with host GO:0044146 9 0.020
cellular catabolic process GO:0044248 372 0.020
Human Worm
cellular homeostasis GO:0019725 80 0.020
response to abiotic stimulus GO:0009628 341 0.020
regulation of protein localization GO:0032880 76 0.020
stem cell differentiation GO:0048863 117 0.020
embryonic axis specification GO:0000578 107 0.020
positive regulation of nucleotide metabolic process GO:0045981 55 0.020
single organism membrane organization GO:0044802 93 0.019
Yeast
nucleoside triphosphate catabolic process GO:0009143 108 0.019
defense response GO:0006952 300 0.019
larval development GO:0002164 104 0.019
Worm
border follicle cell migration GO:0007298 113 0.019
positive regulation of proteolysis GO:0045862 52 0.019
single organism catabolic process GO:0044712 228 0.019
protein deubiquitination GO:0016579 17 0.019
centrosome organization GO:0051297 163 0.019
regulation of nuclear division GO:0051783 58 0.019
ovarian follicle cell stalk formation GO:0030713 17 0.018
protein polymerization GO:0051258 42 0.018
positive regulation of transport GO:0051050 92 0.018
Human
cell cycle phase transition GO:0044770 140 0.018
programmed cell death GO:0012501 257 0.018
negative regulation of cellular catabolic process GO:0031330 34 0.018
response to lipopolysaccharide GO:0032496 4 0.018
cellularization GO:0007349 90 0.018
feeding behavior GO:0007631 50 0.018
positive regulation of nucleoside metabolic process GO:0045979 47 0.018
negative regulation of protein metabolic process GO:0051248 85 0.018
Yeast
regulation of protein modification by small protein conjugation or removal GO:1903320 25 0.018
Yeast
regulation of transport GO:0051049 181 0.018
Human
positive regulation of phosphate metabolic process GO:0045937 139 0.018
stem cell maintenance GO:0019827 67 0.018
spindle organization GO:0007051 253 0.017
regulation of nucleotide catabolic process GO:0030811 48 0.017
signal transduction by phosphorylation GO:0023014 107 0.017
negative regulation of cellular protein metabolic process GO:0032269 85 0.017
Yeast
transition metal ion transport GO:0000041 16 0.017
regulation of synaptic growth at neuromuscular junction GO:0008582 89 0.017
protein import GO:0017038 55 0.017
actin cytoskeleton organization GO:0030036 206 0.017
nucleoside catabolic process GO:0009164 112 0.017
maternal determination of anterior posterior axis embryo GO:0008358 74 0.017
negative regulation of cellular component organization GO:0051129 108 0.017
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.017
Mouse
autophagy GO:0006914 108 0.017
regulation of protein catabolic process GO:0042176 55 0.017
establishment or maintenance of cytoskeleton polarity GO:0030952 44 0.017
regulation of cellular protein catabolic process GO:1903362 44 0.017
tissue migration GO:0090130 155 0.016
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 44 0.016
jak stat cascade GO:0007259 49 0.016
oocyte development GO:0048599 124 0.016
nucleobase containing small molecule metabolic process GO:0055086 174 0.016
wnt signaling pathway GO:0016055 98 0.016
anterior posterior axis specification GO:0009948 109 0.016
negative regulation of epithelial cell proliferation GO:0050680 4 0.016
regulation of gtp catabolic process GO:0033124 44 0.016
negative regulation of phosphorus metabolic process GO:0010563 45 0.016
regulation of purine nucleotide catabolic process GO:0033121 48 0.016
protein complex assembly GO:0006461 200 0.016
cell cell junction assembly GO:0007043 38 0.016
developmental programmed cell death GO:0010623 138 0.016
protein targeting GO:0006605 64 0.015
Yeast
positive regulation of signaling GO:0023056 243 0.015
cation transport GO:0006812 110 0.015
regulation of cell cycle phase transition GO:1901987 130 0.015
vacuolar transport GO:0007034 13 0.015
Yeast
regulation of mitotic cell cycle phase transition GO:1901990 130 0.015
gliogenesis GO:0042063 80 0.015
cellular ketone metabolic process GO:0042180 24 0.015
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.015
Mouse
response to organophosphorus GO:0046683 2 0.015
tube formation GO:0035148 21 0.015
negative regulation of growth GO:0045926 84 0.015
regulation of cell growth GO:0001558 43 0.015
Mouse
negative regulation of cell proliferation GO:0008285 69 0.015
Mouse
regulation of cellular amine metabolic process GO:0033238 3 0.015
purine ribonucleotide metabolic process GO:0009150 145 0.015
mitotic cell cycle phase transition GO:0044772 138 0.015
negative regulation of cell cycle GO:0045786 116 0.014
Mouse
negative regulation of cell cycle process GO:0010948 109 0.014
multicellular organismal aging GO:0010259 140 0.014
retina development in camera type eye GO:0060041 4 0.014
protein phosphorylation GO:0006468 169 0.014
response to fibroblast growth factor GO:0071774 10 0.014
regulation of nucleoside metabolic process GO:0009118 50 0.014
carbohydrate derivative catabolic process GO:1901136 118 0.014
segmentation GO:0035282 207 0.014
aromatic compound catabolic process GO:0019439 166 0.014
hindgut development GO:0061525 58 0.014
establishment of ommatidial planar polarity GO:0042067 49 0.014
purine nucleoside triphosphate metabolic process GO:0009144 119 0.014
maintenance of location GO:0051235 73 0.014
oocyte construction GO:0007308 112 0.014
negative regulation of phosphate metabolic process GO:0045936 45 0.014
oocyte differentiation GO:0009994 145 0.014
cytoskeleton dependent intracellular transport GO:0030705 44 0.014
negative regulation of gene expression GO:0010629 387 0.014
Mouse
synapse assembly GO:0007416 143 0.014
negative regulation of erk1 and erk2 cascade GO:0070373 3 0.014
regulation of protein complex disassembly GO:0043244 29 0.014
compound eye photoreceptor cell differentiation GO:0001751 140 0.014
positive regulation of developmental process GO:0051094 143 0.014
positive regulation of cellular protein metabolic process GO:0032270 118 0.014
imaginal disc derived leg morphogenesis GO:0007480 80 0.013
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 41 0.013
sex differentiation GO:0007548 81 0.013
positive regulation of nucleotide catabolic process GO:0030813 46 0.013
organonitrogen compound catabolic process GO:1901565 128 0.013
positive regulation of intracellular signal transduction GO:1902533 116 0.013
forebrain development GO:0030900 2 0.013
peripheral nervous system development GO:0007422 52 0.013
eye photoreceptor cell fate commitment GO:0042706 37 0.013
leg disc morphogenesis GO:0007478 80 0.013
brain development GO:0007420 120 0.013
pole plasm assembly GO:0007315 61 0.013
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.013
positive regulation of apoptotic signaling pathway GO:2001235 4 0.013
regulation of system process GO:0044057 36 0.013
positive regulation of mapk cascade GO:0043410 63 0.013
inorganic cation transmembrane transport GO:0098662 61 0.013
rna transport GO:0050658 46 0.013
regulation of wnt signaling pathway GO:0030111 68 0.013
synaptic growth at neuromuscular junction GO:0051124 119 0.013
actin polymerization or depolymerization GO:0008154 31 0.012
embryonic pattern specification GO:0009880 174 0.012
negative regulation of multi organism process GO:0043901 29 0.012
muscle organ development GO:0007517 127 0.012
spermatid development GO:0007286 98 0.012
spindle assembly involved in mitosis GO:0090307 50 0.012
maintenance of cell polarity GO:0030011 18 0.012
cellular response to external stimulus GO:0071496 66 0.012
synapse organization GO:0050808 196 0.012
mapk cascade GO:0000165 107 0.012
wound healing GO:0042060 75 0.012
response to temperature stimulus GO:0009266 106 0.012
lipid storage GO:0019915 38 0.012
erk1 and erk2 cascade GO:0070371 39 0.012
establishment of organelle localization GO:0051656 122 0.012
nucleus organization GO:0006997 45 0.012
positive regulation of axonogenesis GO:0050772 2 0.012
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.012
meiotic cytokinesis GO:0033206 33 0.012
regulation of cell differentiation GO:0045595 302 0.012
positive regulation of catabolic process GO:0009896 105 0.012
homeostatic process GO:0042592 199 0.012
actin filament organization GO:0007015 126 0.011
exocytosis GO:0006887 28 0.011
Human

TSG101 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.125
lipid metabolism disorder DOID:3146 0 0.125
inherited metabolic disorder DOID:655 0 0.125
disease of anatomical entity DOID:7 0 0.072
neuromuscular disease DOID:440 0 0.019
charcot marie tooth disease DOID:10595 0 0.019
nervous system disease DOID:863 0 0.019
neuropathy DOID:870 0 0.019
cancer DOID:162 0 0.013
Human
disease of cellular proliferation DOID:14566 0 0.013
Human
organ system cancer DOID:0050686 0 0.013
Human