Drosophila melanogaster

0 known processes

D1 (Dmel_CG9745)

D1 chromosomal protein

(Aliases: dD1,CG9745,Dmel\CG9745,RE69409,EP(3)0473)

D1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of gene expression epigenetic GO:0040029 128 0.991
negative regulation of transcription dna templated GO:0045892 237 0.983
chromatin silencing GO:0006342 76 0.972
negative regulation of rna biosynthetic process GO:1902679 240 0.971
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.954
negative regulation of nucleic acid templated transcription GO:1903507 240 0.954
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.952
negative regulation of cellular biosynthetic process GO:0031327 277 0.947
negative regulation of gene expression GO:0010629 387 0.943
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.942
negative regulation of cellular metabolic process GO:0031324 382 0.941
negative regulation of rna metabolic process GO:0051253 251 0.939
negative regulation of gene expression epigenetic GO:0045814 77 0.926
negative regulation of biosynthetic process GO:0009890 277 0.852
gene silencing GO:0016458 138 0.809
chromosome organization GO:0051276 360 0.756
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.680
covalent chromatin modification GO:0016569 106 0.620
chromatin modification GO:0016568 147 0.606
positive regulation of gene expression GO:0010628 290 0.395
positive regulation of macromolecule metabolic process GO:0010604 405 0.374
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.362
positive regulation of biosynthetic process GO:0009891 316 0.328
chromatin organization GO:0006325 207 0.320
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.289
heterochromatin organization GO:0070828 25 0.259
chromatin remodeling GO:0006338 72 0.257
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.249
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.246
protein dna complex subunit organization GO:0071824 86 0.232
positive regulation of rna metabolic process GO:0051254 271 0.218
positive regulation of cellular biosynthetic process GO:0031328 316 0.196
positive regulation of transcription dna templated GO:0045893 266 0.193
dna repair GO:0006281 54 0.172
regulation of chromatin silencing GO:0031935 36 0.166
chromatin assembly or disassembly GO:0006333 52 0.158
histone exchange GO:0043486 21 0.146
chromosome segregation GO:0007059 157 0.138
nucleosome organization GO:0034728 59 0.130
mitotic spindle organization GO:0007052 220 0.126
negative regulation of cell cycle process GO:0010948 109 0.125
cell proliferation GO:0008283 299 0.121
macromolecular complex assembly GO:0065003 256 0.117
cellular macromolecular complex assembly GO:0034622 153 0.114
positive regulation of rna biosynthetic process GO:1902680 266 0.101
stem cell maintenance GO:0019827 67 0.099
regulation of heterochromatin assembly GO:0031445 8 0.094
embryonic morphogenesis GO:0048598 206 0.088
negative regulation of cellular component organization GO:0051129 108 0.088
protein dna complex assembly GO:0065004 63 0.083
rna splicing GO:0008380 83 0.081
posttranscriptional gene silencing GO:0016441 46 0.080
spindle organization GO:0007051 253 0.076
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.075
positive regulation of nucleic acid templated transcription GO:1903508 266 0.073
chromatin assembly GO:0031497 48 0.072
regulation of cellular component biogenesis GO:0044087 201 0.070
single organism behavior GO:0044708 391 0.070
positive regulation of cellular protein metabolic process GO:0032270 118 0.070
response to abiotic stimulus GO:0009628 341 0.067
dna packaging GO:0006323 91 0.066
regulation of chromatin assembly GO:0010847 9 0.066
regulation of cellular protein metabolic process GO:0032268 243 0.065
dna metabolic process GO:0006259 227 0.065
endocytosis GO:0006897 310 0.064
organonitrogen compound metabolic process GO:1901564 318 0.064
mitotic nuclear division GO:0007067 213 0.064
regulation of chromatin organization GO:1902275 32 0.063
mrna metabolic process GO:0016071 124 0.062
intracellular transport GO:0046907 228 0.059
programmed cell death GO:0012501 257 0.058
dna conformation change GO:0071103 105 0.057
regulation of dna metabolic process GO:0051052 34 0.056
death GO:0016265 284 0.053
regulation of chromatin modification GO:1903308 28 0.051
g2 dna damage checkpoint GO:0031572 69 0.050
regulation of ras protein signal transduction GO:0046578 93 0.050
transcription elongation from rna polymerase ii promoter GO:0006368 18 0.050
regulation of gene silencing GO:0060968 63 0.049
histone h4 k20 methylation GO:0034770 4 0.048
regulation of intracellular signal transduction GO:1902531 236 0.045
response to alcohol GO:0097305 95 0.044
transcription from rna polymerase ii promoter GO:0006366 368 0.044
tricarboxylic acid metabolic process GO:0072350 1 0.043
negative regulation of cellular protein metabolic process GO:0032269 85 0.042
embryo development ending in birth or egg hatching GO:0009792 152 0.042
mrna processing GO:0006397 104 0.042
regulation of chromosome organization GO:0033044 64 0.039
atp dependent chromatin remodeling GO:0043044 22 0.038
mitotic sister chromatid segregation GO:0000070 87 0.038
mitotic dna damage checkpoint GO:0044773 74 0.038
imaginal disc derived appendage development GO:0048737 399 0.037
cellular response to dna damage stimulus GO:0006974 223 0.037
adult behavior GO:0030534 137 0.037
phosphorylation GO:0016310 294 0.037
amine metabolic process GO:0009308 12 0.036
positive regulation of phosphate metabolic process GO:0045937 139 0.036
regulation of cell differentiation GO:0045595 302 0.035
negative regulation of protein metabolic process GO:0051248 85 0.034
histone modification GO:0016570 106 0.034
mitotic g2 dna damage checkpoint GO:0007095 69 0.033
positive regulation of cellular component organization GO:0051130 156 0.033
negative regulation of organelle organization GO:0010639 56 0.033
response to organic substance GO:0010033 284 0.032
regulation of multi organism process GO:0043900 131 0.032
homeostatic process GO:0042592 199 0.031
regulation of cell cycle GO:0051726 291 0.031
regulation of translation GO:0006417 56 0.030
dna templated transcription elongation GO:0006354 18 0.030
regulation of purine nucleotide metabolic process GO:1900542 62 0.029
organelle fission GO:0048285 340 0.029
chromatin silencing at centromere GO:0030702 3 0.029
compound eye photoreceptor cell differentiation GO:0001751 140 0.029
nucleus organization GO:0006997 45 0.028
regionalization GO:0003002 416 0.027
regulation of molecular function GO:0065009 217 0.027
neuron projection guidance GO:0097485 241 0.027
phagocytosis GO:0006909 215 0.026
apoptotic process GO:0006915 159 0.026
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 73 0.026
mitotic g2 m transition checkpoint GO:0044818 70 0.026
posttranscriptional regulation of gene expression GO:0010608 145 0.025
nucleosome mobilization GO:0042766 9 0.025
response to dsrna GO:0043331 15 0.025
vesicle mediated transport GO:0016192 381 0.025
intracellular signal transduction GO:0035556 300 0.024
immune system process GO:0002376 347 0.024
rna processing GO:0006396 147 0.024
neurological system process GO:0050877 358 0.024
establishment of localization in cell GO:0051649 402 0.023
stem cell development GO:0048864 79 0.023
regulation of cell cycle process GO:0010564 181 0.023
regulation of mitotic cell cycle GO:0007346 190 0.023
posttranscriptional gene silencing by rna GO:0035194 45 0.023
histone h2a acetylation GO:0043968 1 0.023
protein complex biogenesis GO:0070271 201 0.022
regulation of cell proliferation GO:0042127 163 0.022
histone deacetylation GO:0016575 9 0.022
cell death GO:0008219 279 0.022
regulation of phosphorylation GO:0042325 147 0.022
intraspecies interaction between organisms GO:0051703 4 0.022
post embryonic appendage morphogenesis GO:0035120 385 0.022
establishment or maintenance of cell polarity GO:0007163 167 0.022
protein modification process GO:0036211 438 0.022
regulation of phosphorus metabolic process GO:0051174 210 0.022
protein localization GO:0008104 284 0.022
regulation of cell cycle phase transition GO:1901987 130 0.021
compound eye development GO:0048749 307 0.021
male mating behavior GO:0060179 70 0.021
telencephalon development GO:0021537 2 0.021
eye morphogenesis GO:0048592 260 0.020
positive regulation of organelle organization GO:0010638 65 0.020
cell cycle phase transition GO:0044770 140 0.020
regulation of meiosis GO:0040020 3 0.020
appendage development GO:0048736 401 0.020
cellular catabolic process GO:0044248 372 0.020
negative regulation of cell differentiation GO:0045596 143 0.020
organelle assembly GO:0070925 198 0.020
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.020
oxoacid metabolic process GO:0043436 103 0.020
dna replication GO:0006260 48 0.020
regulation of cellular amino acid metabolic process GO:0006521 0 0.020
positive regulation of mrna processing GO:0050685 4 0.019
regulation of cellular amine metabolic process GO:0033238 3 0.019
anatomical structure homeostasis GO:0060249 97 0.019
protein complex assembly GO:0006461 200 0.019
multi organism behavior GO:0051705 175 0.019
enzyme linked receptor protein signaling pathway GO:0007167 179 0.019
mitotic cytokinesis GO:0000281 50 0.019
muscle organ development GO:0007517 127 0.018
regulation of cell morphogenesis GO:0022604 163 0.018
cellular protein localization GO:0034613 160 0.018
positive regulation of cell communication GO:0010647 250 0.018
sensory organ morphogenesis GO:0090596 260 0.018
ovulation cycle GO:0042698 1 0.018
negative regulation of developmental process GO:0051093 201 0.018
regulation of phosphatase activity GO:0010921 3 0.017
cellular amine metabolic process GO:0044106 12 0.017
response to other organism GO:0051707 293 0.017
positive regulation of phosphorus metabolic process GO:0010562 139 0.017
rna splicing via transesterification reactions GO:0000375 73 0.017
nucleosome positioning GO:0016584 3 0.017
regulation of phosphate metabolic process GO:0019220 210 0.017
regulation of mrna metabolic process GO:1903311 72 0.017
histone lysine methylation GO:0034968 32 0.016
response to heat GO:0009408 63 0.016
locomotory behavior GO:0007626 176 0.016
cellular protein modification process GO:0006464 438 0.015
negative regulation of chromatin silencing GO:0031936 9 0.015
mitotic cell cycle phase transition GO:0044772 138 0.015
mrna splice site selection GO:0006376 1 0.015
multi multicellular organism process GO:0044706 123 0.015
aging GO:0007568 143 0.015
meiotic cell cycle process GO:1903046 132 0.015
cytoskeleton dependent cytokinesis GO:0061640 81 0.015
mrna splicing via spliceosome GO:0000398 73 0.015
protein transport GO:0015031 155 0.015
actin filament based process GO:0030029 220 0.015
gene silencing by rna GO:0031047 57 0.015
peptidyl lysine trimethylation GO:0018023 6 0.015
compound eye morphogenesis GO:0001745 249 0.014
negative regulation of protein phosphorylation GO:0001933 17 0.014
regulation of mrna processing GO:0050684 71 0.014
cell aging GO:0007569 2 0.014
cognition GO:0050890 141 0.014
cellular amino acid metabolic process GO:0006520 61 0.014
cell cycle checkpoint GO:0000075 95 0.014
salivary gland development GO:0007431 162 0.014
positive regulation of epidermal growth factor activated receptor activity GO:0045741 1 0.014
cellular response to sterol depletion GO:0071501 3 0.014
organic acid metabolic process GO:0006082 103 0.014
nuclear transport GO:0051169 72 0.014
positive regulation of response to stimulus GO:0048584 323 0.014
regulation of rna splicing GO:0043484 69 0.014
axon development GO:0061564 297 0.013
regulation of mitotic cell cycle phase transition GO:1901990 130 0.013
nuclear body organization GO:0030575 6 0.013
nucleobase containing compound transport GO:0015931 56 0.013
carboxylic acid metabolic process GO:0019752 92 0.013
negative regulation of purine nucleotide catabolic process GO:0033122 1 0.013
rna interference GO:0016246 27 0.013
positive regulation of gene expression epigenetic GO:0045815 16 0.012
dna damage checkpoint GO:0000077 78 0.012
organophosphate metabolic process GO:0019637 195 0.012
positive regulation of signal transduction GO:0009967 223 0.012
embryonic development via the syncytial blastoderm GO:0001700 148 0.012
respiratory system development GO:0060541 213 0.012
positive regulation of cellular amine metabolic process GO:0033240 0 0.012
regulation of apoptotic process GO:0042981 130 0.012
regulation of catalytic activity GO:0050790 185 0.012
mitotic cell cycle checkpoint GO:0007093 88 0.012
regulation of proteasomal protein catabolic process GO:0061136 39 0.012
regulation of compound eye cone cell fate specification GO:0042682 4 0.012
regulation of response to stress GO:0080134 200 0.012
regulation of programmed cell death GO:0043067 152 0.012
small molecule metabolic process GO:0044281 305 0.011
tissue morphogenesis GO:0048729 297 0.011
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.011
regulation of cellular catabolic process GO:0031329 157 0.011
regulation of chromatin assembly or disassembly GO:0001672 12 0.011
positive regulation of chromatin silencing GO:0031937 16 0.011
regulation of transport GO:0051049 181 0.011
chromosome condensation GO:0030261 41 0.011
mitotic dna integrity checkpoint GO:0044774 75 0.011
negative regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032435 16 0.011
tissue migration GO:0090130 155 0.011
positive regulation of cell proliferation GO:0008284 47 0.011
digestive system development GO:0055123 149 0.011
negative regulation of multicellular organismal process GO:0051241 142 0.011
histone methylation GO:0016571 40 0.011
salivary gland morphogenesis GO:0007435 145 0.011
nucleocytoplasmic transport GO:0006913 72 0.011
chromatin mediated maintenance of transcription GO:0048096 7 0.010
positive regulation of intracellular signal transduction GO:1902533 116 0.010
translation GO:0006412 69 0.010
spliceosomal complex assembly GO:0000245 1 0.010
negative regulation of chromosome organization GO:2001251 19 0.010
dna templated transcription initiation GO:0006352 25 0.010
negative regulation of growth GO:0045926 84 0.010

D1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.025
disease of cellular proliferation DOID:14566 0 0.025
organ system cancer DOID:0050686 0 0.025
disease of anatomical entity DOID:7 0 0.014
nervous system disease DOID:863 0 0.014
muscular disease DOID:0080000 0 0.010
musculoskeletal system disease DOID:17 0 0.010
muscle tissue disease DOID:66 0 0.010