Drosophila melanogaster

98 known processes

Tbp (Dmel_CG9874)

TATA binding protein

(Aliases: dTFIID,Dmel\CG9874,dTBP,CG9874,RBP,dTbp,TFIID,TBP,TBP38,TFIIDtau,TfIID)

Tbp biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
positive regulation of rna biosynthetic process GO:1902680 266 0.834
positive regulation of nucleic acid templated transcription GO:1903508 266 0.733
negative regulation of rna biosynthetic process GO:1902679 240 0.672
positive regulation of macromolecule metabolic process GO:0010604 405 0.601
positive regulation of cellular biosynthetic process GO:0031328 316 0.500
positive regulation of rna metabolic process GO:0051254 271 0.492
chromosome organization GO:0051276 360 0.477
meiotic cell cycle process GO:1903046 132 0.470
gene silencing GO:0016458 138 0.469
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.462
positive regulation of transcription dna templated GO:0045893 266 0.461
rna polymerase ii transcriptional preinitiation complex assembly GO:0051123 20 0.453
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.433
dendrite morphogenesis GO:0048813 199 0.413
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.404
nuclear division GO:0000280 332 0.387
tissue morphogenesis GO:0048729 297 0.326
positive regulation of gene expression GO:0010628 290 0.306
male gamete generation GO:0048232 201 0.304
Rat
chromatin organization GO:0006325 207 0.295
regulation of cell cycle process GO:0010564 181 0.295
chromatin modification GO:0016568 147 0.291
cell division GO:0051301 248 0.271
response to external biotic stimulus GO:0043207 293 0.257
morphogenesis of an epithelium GO:0002009 276 0.242
transcription from rna polymerase ii promoter GO:0006366 368 0.229
dna templated transcriptional preinitiation complex assembly GO:0070897 20 0.228
developmental growth GO:0048589 280 0.215
regulation of cell cycle GO:0051726 291 0.200
dna templated transcription initiation GO:0006352 25 0.199
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.196
meiosis i GO:0007127 59 0.196
negative regulation of nucleic acid templated transcription GO:1903507 240 0.194
negative regulation of cellular metabolic process GO:0031324 382 0.182
tube development GO:0035295 244 0.170
positive regulation of biosynthetic process GO:0009891 316 0.166
meiotic nuclear division GO:0007126 151 0.163
negative regulation of gene expression GO:0010629 387 0.153
organic substance transport GO:0071702 257 0.148
chromatin silencing GO:0006342 76 0.146
negative regulation of transcription dna templated GO:0045892 237 0.146
covalent chromatin modification GO:0016569 106 0.141
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.130
muscle structure development GO:0061061 224 0.128
negative regulation of biosynthetic process GO:0009890 277 0.126
regulation of multicellular organismal development GO:2000026 414 0.119
dendrite development GO:0016358 204 0.117
negative regulation of rna metabolic process GO:0051253 251 0.116
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.112
protein dna complex subunit organization GO:0071824 86 0.109
immune system process GO:0002376 347 0.104
growth GO:0040007 359 0.098
regulation of mitotic cell cycle GO:0007346 190 0.097
regulation of gene expression epigenetic GO:0040029 128 0.094
regulation of catabolic process GO:0009894 170 0.092
meiotic cell cycle GO:0051321 171 0.083
negative regulation of gene expression epigenetic GO:0045814 77 0.083
neuron projection guidance GO:0097485 241 0.080
imaginal disc derived appendage morphogenesis GO:0035114 395 0.075
protein dna complex assembly GO:0065004 63 0.074
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.073
developmental programmed cell death GO:0010623 138 0.072
gland morphogenesis GO:0022612 145 0.071
regulation of mitotic cell cycle phase transition GO:1901990 130 0.071
positive regulation of response to stimulus GO:0048584 323 0.067
negative regulation of cell communication GO:0010648 223 0.066
protein localization GO:0008104 284 0.063
histone modification GO:0016570 106 0.063
transcription initiation from rna polymerase ii promoter GO:0006367 25 0.063
cellular protein localization GO:0034613 160 0.063
regulation of cellular response to stress GO:0080135 89 0.061
regulation of gene silencing GO:0060968 63 0.060
regulation of cell death GO:0010941 173 0.059
cell migration GO:0016477 238 0.059
appendage morphogenesis GO:0035107 397 0.058
regulation of growth GO:0040008 233 0.058
regionalization GO:0003002 416 0.056
organonitrogen compound metabolic process GO:1901564 318 0.055
regulation of cell cycle phase transition GO:1901987 130 0.055
ribonucleoside metabolic process GO:0009119 127 0.055
epithelial cell differentiation GO:0030855 322 0.053
epithelial tube morphogenesis GO:0060562 88 0.052
ovarian follicle cell migration GO:0007297 121 0.051
appendage development GO:0048736 401 0.050
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.050
response to other organism GO:0051707 293 0.050
taxis GO:0042330 304 0.049
response to biotic stimulus GO:0009607 294 0.049
mitotic nuclear division GO:0007067 213 0.049
positive regulation of cellular protein metabolic process GO:0032270 118 0.049
establishment of protein localization GO:0045184 163 0.047
positive regulation of developmental growth GO:0048639 62 0.047
regulation of response to stress GO:0080134 200 0.045
imaginal disc derived appendage development GO:0048737 399 0.045
death GO:0016265 284 0.045
axon development GO:0061564 297 0.044
internal protein amino acid acetylation GO:0006475 38 0.044
regulation of cellular catabolic process GO:0031329 157 0.043
ncrna metabolic process GO:0034660 43 0.043
positive regulation of developmental process GO:0051094 143 0.043
protein acylation GO:0043543 42 0.043
regulation of chromatin silencing GO:0031935 36 0.042
oxoacid metabolic process GO:0043436 103 0.042
eggshell chorion assembly GO:0007306 66 0.042
cellular macromolecule localization GO:0070727 220 0.042
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.041
axon guidance GO:0007411 233 0.040
rna processing GO:0006396 147 0.040
embryonic development via the syncytial blastoderm GO:0001700 148 0.040
organic substance catabolic process GO:1901575 308 0.039
cellular protein modification process GO:0006464 438 0.039
programmed cell death GO:0012501 257 0.039
catabolic process GO:0009056 409 0.037
mitotic cell cycle embryonic GO:0045448 38 0.036
cellular component assembly involved in morphogenesis GO:0010927 151 0.035
mitotic cell cycle phase transition GO:0044772 138 0.035
apoptotic process GO:0006915 159 0.035
axonogenesis GO:0007409 290 0.035
cellular response to organic substance GO:0071310 132 0.035
protein import into nucleus GO:0006606 51 0.034
guanosine containing compound catabolic process GO:1901069 74 0.034
histone acetylation GO:0016573 38 0.033
positive regulation of growth GO:0045927 75 0.033
negative regulation of cellular biosynthetic process GO:0031327 277 0.033
mrna metabolic process GO:0016071 124 0.033
regulation of organelle organization GO:0033043 196 0.033
negative regulation of response to stimulus GO:0048585 258 0.032
chromatin assembly or disassembly GO:0006333 52 0.032
exocrine system development GO:0035272 162 0.032
defense response to other organism GO:0098542 225 0.032
regulation of molecular function GO:0065009 217 0.032
dna metabolic process GO:0006259 227 0.032
Yeast
enzyme linked receptor protein signaling pathway GO:0007167 179 0.032
peptidyl lysine acetylation GO:0018394 39 0.031
negative regulation of signal transduction GO:0009968 206 0.030
negative regulation of developmental process GO:0051093 201 0.030
compound eye development GO:0048749 307 0.030
regulation of programmed cell death GO:0043067 152 0.030
negative regulation of cell death GO:0060548 81 0.030
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.030
cell proliferation GO:0008283 299 0.029
protein modification process GO:0036211 438 0.029
columnar cuboidal epithelial cell development GO:0002066 249 0.029
single organism biosynthetic process GO:0044711 206 0.029
positive regulation of cell communication GO:0010647 250 0.028
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.028
regulation of cell proliferation GO:0042127 163 0.028
digestive system development GO:0055123 149 0.028
morphogenesis of embryonic epithelium GO:0016331 94 0.027
protein localization to organelle GO:0033365 82 0.027
cellular response to chemical stimulus GO:0070887 199 0.027
negative regulation of cell differentiation GO:0045596 143 0.027
chorion containing eggshell formation GO:0007304 105 0.027
carboxylic acid metabolic process GO:0019752 92 0.026
positive regulation of multicellular organismal process GO:0051240 143 0.026
neuron fate commitment GO:0048663 50 0.026
negative regulation of signaling GO:0023057 219 0.026
ribose phosphate metabolic process GO:0019693 145 0.026
antimicrobial humoral response GO:0019730 99 0.025
anterior posterior pattern specification GO:0009952 136 0.025
wing disc morphogenesis GO:0007472 344 0.025
male meiosis GO:0007140 52 0.025
tissue migration GO:0090130 155 0.025
regulation of apoptotic process GO:0042981 130 0.025
peptidyl amino acid modification GO:0018193 105 0.025
positive regulation of signaling GO:0023056 243 0.024
eye development GO:0001654 323 0.024
embryo development ending in birth or egg hatching GO:0009792 152 0.024
regulation of protein catabolic process GO:0042176 55 0.024
cellular macromolecule catabolic process GO:0044265 136 0.024
positive regulation of signal transduction GO:0009967 223 0.024
phagocytosis GO:0006909 215 0.024
protein import GO:0017038 55 0.024
dna damage checkpoint GO:0000077 78 0.024
cellular macromolecular complex assembly GO:0034622 153 0.023
negative regulation of apoptotic process GO:0043066 63 0.023
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 44 0.023
organic acid metabolic process GO:0006082 103 0.022
salivary gland cell autophagic cell death GO:0035071 83 0.022
carbohydrate derivative biosynthetic process GO:1901137 85 0.022
cellular ketone metabolic process GO:0042180 24 0.022
negative regulation of programmed cell death GO:0043069 72 0.021
regulation of cell differentiation GO:0045595 302 0.021
histolysis GO:0007559 102 0.021
regulation of embryonic development GO:0045995 68 0.021
humoral immune response GO:0006959 117 0.021
open tracheal system development GO:0007424 204 0.020
stem cell division GO:0017145 69 0.020
regulation of developmental growth GO:0048638 174 0.020
salivary gland development GO:0007431 162 0.020
cell death GO:0008219 279 0.019
mitotic spindle organization GO:0007052 220 0.019
spindle organization GO:0007051 253 0.019
ovarian follicle cell development GO:0030707 248 0.019
spermatogenesis GO:0007283 200 0.019
Rat
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.019
organelle fission GO:0048285 340 0.019
neuroblast proliferation GO:0007405 74 0.019
nucleoside phosphate catabolic process GO:1901292 110 0.019
salivary gland morphogenesis GO:0007435 145 0.018
histone h3 acetylation GO:0043966 11 0.018
small molecule metabolic process GO:0044281 305 0.018
branching morphogenesis of an epithelial tube GO:0048754 45 0.018
reproductive system development GO:0061458 74 0.018
regulation of anatomical structure morphogenesis GO:0022603 242 0.018
single organism intracellular transport GO:1902582 207 0.018
salivary gland histolysis GO:0035070 88 0.018
protein acetylation GO:0006473 39 0.018
regulation of catalytic activity GO:0050790 185 0.017
intracellular protein transport GO:0006886 104 0.017
chromosome segregation GO:0007059 157 0.017
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 38 0.017
purine ribonucleotide catabolic process GO:0009154 109 0.017
anatomical structure homeostasis GO:0060249 97 0.017
regulation of chromosome organization GO:0033044 64 0.017
multicellular organism growth GO:0035264 46 0.017
sensory organ morphogenesis GO:0090596 260 0.017
regulation of multicellular organism growth GO:0040014 40 0.017
eggshell formation GO:0030703 105 0.017
reproductive structure development GO:0048608 74 0.017
positive regulation of cell proliferation GO:0008284 47 0.017
muscle organ development GO:0007517 127 0.017
cellular amino acid metabolic process GO:0006520 61 0.017
purine nucleoside metabolic process GO:0042278 127 0.016
regulation of cellular protein metabolic process GO:0032268 243 0.016
sister chromatid segregation GO:0000819 92 0.016
cardiovascular system development GO:0072358 82 0.016
epithelium migration GO:0090132 148 0.016
regulation of wnt signaling pathway GO:0030111 68 0.016
gland development GO:0048732 191 0.016
regulation of tube architecture open tracheal system GO:0035152 68 0.016
cellular amide metabolic process GO:0043603 80 0.016
aromatic compound catabolic process GO:0019439 166 0.016
protein localization to chromatin GO:0071168 3 0.016
nucleobase containing compound catabolic process GO:0034655 165 0.016
regulation of localization GO:0032879 275 0.016
cellular response to biotic stimulus GO:0071216 4 0.016
respiratory system development GO:0060541 213 0.016
brain development GO:0007420 120 0.015
vesicle mediated transport GO:0016192 381 0.015
r7 cell differentiation GO:0045466 43 0.015
hindgut morphogenesis GO:0007442 58 0.015
establishment or maintenance of cell polarity GO:0007163 167 0.015
dorsal appendage formation GO:0046843 47 0.015
cuticle development GO:0042335 86 0.015
regulation of cellular protein catabolic process GO:1903362 44 0.015
chemotaxis GO:0006935 249 0.015
cell cycle comprising mitosis without cytokinesis GO:0033301 25 0.015
response to bacterium GO:0009617 198 0.015
cellular catabolic process GO:0044248 372 0.015
regulation of protein metabolic process GO:0051246 256 0.015
regulation of cell division GO:0051302 72 0.015
posttranscriptional regulation of gene expression GO:0010608 145 0.015
post embryonic appendage morphogenesis GO:0035120 385 0.015
protein transport GO:0015031 155 0.014
single organism catabolic process GO:0044712 228 0.014
actin cytoskeleton organization GO:0030036 206 0.014
response to fungus GO:0009620 50 0.014
imaginal disc pattern formation GO:0007447 91 0.014
segmentation GO:0035282 207 0.014
single organism behavior GO:0044708 391 0.014
digestive tract morphogenesis GO:0048546 127 0.014
intracellular transport GO:0046907 228 0.014
regulation of response to external stimulus GO:0032101 115 0.013
single organism nuclear import GO:1902593 51 0.013
somatic stem cell division GO:0048103 37 0.013
organic cyclic compound catabolic process GO:1901361 168 0.013
g1 s transition of mitotic cell cycle GO:0000082 31 0.013
epithelial cell development GO:0002064 274 0.013
protein processing GO:0016485 68 0.013
nucleoside metabolic process GO:0009116 127 0.013
regulation of response to biotic stimulus GO:0002831 63 0.013
telencephalon development GO:0021537 2 0.013
digestive tract development GO:0048565 149 0.013
tissue death GO:0016271 102 0.013
photoreceptor cell fate commitment GO:0046552 41 0.013
ameboidal type cell migration GO:0001667 151 0.013
regulation of proteasomal protein catabolic process GO:0061136 39 0.013
chaeta development GO:0022416 97 0.013
epithelial cell migration GO:0010631 148 0.013
cell cycle g1 s phase transition GO:0044843 31 0.012
chitin based cuticle development GO:0040003 49 0.012
protein catabolic process GO:0030163 101 0.012
establishment of protein localization to organelle GO:0072594 62 0.012
cell fate specification GO:0001708 71 0.012
macromolecule catabolic process GO:0009057 161 0.012
dna conformation change GO:0071103 105 0.012
positive regulation of cellular catabolic process GO:0031331 95 0.012
proteolysis GO:0006508 192 0.012
cellular response to organic cyclic compound GO:0071407 32 0.012
glycosyl compound metabolic process GO:1901657 127 0.012
negative regulation of cell cycle GO:0045786 116 0.012
positive regulation of multicellular organism growth GO:0040018 21 0.012
tube morphogenesis GO:0035239 191 0.012
cell motility GO:0048870 251 0.011
positive regulation of intracellular signal transduction GO:1902533 116 0.011
camera type eye development GO:0043010 4 0.011
heterocycle catabolic process GO:0046700 166 0.011
purine ribonucleoside catabolic process GO:0046130 112 0.011
establishment of localization in cell GO:0051649 402 0.011
apoptotic signaling pathway GO:0097190 27 0.011
circulatory system development GO:0072359 82 0.011
reciprocal dna recombination GO:0035825 19 0.011
cellular response to dna damage stimulus GO:0006974 223 0.011
chaeta morphogenesis GO:0008407 42 0.011
establishment of planar polarity GO:0001736 87 0.011
nitrogen compound transport GO:0071705 85 0.011
regulation of cellular amine metabolic process GO:0033238 3 0.011
cell cycle phase transition GO:0044770 140 0.011
male sex differentiation GO:0046661 25 0.010
internal peptidyl lysine acetylation GO:0018393 38 0.010
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.010
meiotic dna double strand break formation GO:0042138 1 0.010
regulation of intracellular signal transduction GO:1902531 236 0.010
regulation of cellular ketone metabolic process GO:0010565 3 0.010
positive regulation of cellular amine metabolic process GO:0033240 0 0.010

Tbp disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org