Drosophila melanogaster

90 known processes

TH1 (Dmel_CG9984)

CG9984 gene product from transcript CG9984-RA

(Aliases: Dmel\CG9984,CG9984,NELF-D,NELF)

TH1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
nuclear division GO:0000280 332 0.375
cell division GO:0051301 248 0.157
transcription from rna polymerase ii promoter GO:0006366 368 0.152
eye development GO:0001654 323 0.120
chromatin remodeling GO:0006338 72 0.105
reproductive behavior GO:0019098 122 0.105
regulation of cell cycle process GO:0010564 181 0.102
cell motility GO:0048870 251 0.092
compound eye development GO:0048749 307 0.089
chromatin modification GO:0016568 147 0.085
regulation of catabolic process GO:0009894 170 0.085
catabolic process GO:0009056 409 0.078
nucleoside phosphate metabolic process GO:0006753 162 0.073
cellular protein localization GO:0034613 160 0.072
multicellular organismal reproductive behavior GO:0033057 110 0.072
response to external biotic stimulus GO:0043207 293 0.072
neurological system process GO:0050877 358 0.069
gliogenesis GO:0042063 80 0.066
retina development in camera type eye GO:0060041 4 0.064
protein dna complex assembly GO:0065004 63 0.064
regulation of neurogenesis GO:0050767 158 0.063
single organism intracellular transport GO:1902582 207 0.062
regulation of cell cycle GO:0051726 291 0.060
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.059
oxidation reduction process GO:0055114 123 0.057
nucleoside triphosphate metabolic process GO:0009141 120 0.056
regulation of intracellular signal transduction GO:1902531 236 0.056
phagocytosis GO:0006909 215 0.054
regulation of cytoplasmic transport GO:1903649 47 0.053
axis specification GO:0009798 167 0.053
negative regulation of cellular biosynthetic process GO:0031327 277 0.052
regulation of organelle organization GO:0033043 196 0.052
cellular chemical homeostasis GO:0055082 40 0.051
regulation of cellular ketone metabolic process GO:0010565 3 0.049
positive regulation of macromolecule metabolic process GO:0010604 405 0.048
positive regulation of cellular component biogenesis GO:0044089 80 0.048
single organism catabolic process GO:0044712 228 0.047
regionalization GO:0003002 416 0.047
regulation of localization GO:0032879 275 0.046
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.046
photoreceptor cell differentiation GO:0046530 170 0.046
purine nucleoside triphosphate catabolic process GO:0009146 108 0.045
ras protein signal transduction GO:0007265 88 0.045
body morphogenesis GO:0010171 2 0.045
negative regulation of developmental process GO:0051093 201 0.044
regulation of gtpase activity GO:0043087 44 0.044
response to nutrient levels GO:0031667 114 0.043
protein modification process GO:0036211 438 0.042
regulation of meiosis GO:0040020 3 0.042
response to other organism GO:0051707 293 0.041
organophosphate catabolic process GO:0046434 112 0.040
transmembrane transport GO:0055085 139 0.040
secondary metabolic process GO:0019748 75 0.039
cellular response to chemical stimulus GO:0070887 199 0.038
carboxylic acid metabolic process GO:0019752 92 0.038
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.038
negative regulation of rna biosynthetic process GO:1902679 240 0.036
eye photoreceptor cell development GO:0042462 81 0.036
cellular homeostasis GO:0019725 80 0.036
endocytosis GO:0006897 310 0.035
regulation of cell cycle g1 s phase transition GO:1902806 23 0.035
cellular protein modification process GO:0006464 438 0.035
glycosyl compound catabolic process GO:1901658 112 0.035
determination of dorsal ventral asymmetry GO:0048262 3 0.035
metal ion homeostasis GO:0055065 44 0.035
positive regulation of gtpase activity GO:0043547 43 0.033
organic substance catabolic process GO:1901575 308 0.032
organonitrogen compound metabolic process GO:1901564 318 0.032
positive regulation of mitotic cell cycle phase transition GO:1901992 20 0.032
eye morphogenesis GO:0048592 260 0.031
intracellular protein transport GO:0006886 104 0.031
pole plasm oskar mrna localization GO:0045451 46 0.031
negative regulation of cell cycle process GO:0010948 109 0.031
chromosome organization GO:0051276 360 0.031
vesicle mediated transport GO:0016192 381 0.031
brain development GO:0007420 120 0.031
nucleobase containing compound catabolic process GO:0034655 165 0.031
regulation of mitotic cell cycle GO:0007346 190 0.031
dna metabolic process GO:0006259 227 0.030
protein localization GO:0008104 284 0.030
multi multicellular organism process GO:0044706 123 0.030
chromatin assembly GO:0031497 48 0.030
multi organism reproductive behavior GO:0044705 121 0.030
histone h2a acetylation GO:0043968 1 0.029
negative regulation of cell cycle phase transition GO:1901988 103 0.029
positive regulation of protein metabolic process GO:0051247 128 0.029
organonitrogen compound catabolic process GO:1901565 128 0.029
intracellular signal transduction GO:0035556 300 0.029
cellular macromolecule localization GO:0070727 220 0.029
chromatin assembly or disassembly GO:0006333 52 0.029
localization of cell GO:0051674 257 0.029
meiotic cell cycle GO:0051321 171 0.028
organelle fission GO:0048285 340 0.028
head development GO:0060322 135 0.028
establishment of protein localization GO:0045184 163 0.028
compound eye photoreceptor development GO:0042051 78 0.028
chemical homeostasis GO:0048878 92 0.027
epithelial cell development GO:0002064 274 0.027
covalent chromatin modification GO:0016569 106 0.027
regulation of intracellular transport GO:0032386 64 0.027
cell cell junction organization GO:0045216 55 0.027
cellular response to monosaccharide stimulus GO:0071326 2 0.027
actin filament based process GO:0030029 220 0.026
ribonucleotide catabolic process GO:0009261 109 0.026
response to alcohol GO:0097305 95 0.026
chorion containing eggshell formation GO:0007304 105 0.026
compound eye morphogenesis GO:0001745 249 0.026
positive regulation of catabolic process GO:0009896 105 0.026
positive regulation of phosphate metabolic process GO:0045937 139 0.026
regulation of cellular localization GO:0060341 136 0.025
rna processing GO:0006396 147 0.025
muscle organ development GO:0007517 127 0.025
single organism carbohydrate metabolic process GO:0044723 72 0.025
cytoskeleton dependent cytokinesis GO:0061640 81 0.025
negative regulation of cell differentiation GO:0045596 143 0.024
cellular ion homeostasis GO:0006873 39 0.024
regulation of protein metabolic process GO:0051246 256 0.024
guanosine containing compound catabolic process GO:1901069 74 0.024
death GO:0016265 284 0.024
compound eye photoreceptor cell differentiation GO:0001751 140 0.023
regulation of nucleocytoplasmic transport GO:0046822 35 0.023
negative regulation of mitotic cell cycle GO:0045930 109 0.023
cellular catabolic process GO:0044248 372 0.023
rrna processing GO:0006364 3 0.023
cytokinesis GO:0000910 90 0.023
small gtpase mediated signal transduction GO:0007264 88 0.023
positive regulation of transcription dna templated GO:0045893 266 0.023
homeostatic process GO:0042592 199 0.022
negative regulation of meiotic cell cycle GO:0051447 2 0.022
cellular ketone metabolic process GO:0042180 24 0.022
dna repair GO:0006281 54 0.022
regulation of nuclear division GO:0051783 58 0.022
purine ribonucleotide catabolic process GO:0009154 109 0.022
regulation of cellular amino acid metabolic process GO:0006521 0 0.021
response to extracellular stimulus GO:0009991 116 0.021
glial cell migration GO:0008347 31 0.021
regulation of g1 s transition of mitotic cell cycle GO:2000045 23 0.021
gtp catabolic process GO:0006184 72 0.021
eye photoreceptor cell differentiation GO:0001754 145 0.021
locomotory behavior GO:0007626 176 0.021
actin cytoskeleton organization GO:0030036 206 0.021
cellular response to hexose stimulus GO:0071331 1 0.020
response to oxygen containing compound GO:1901700 200 0.020
nucleoside metabolic process GO:0009116 127 0.020
dna conformation change GO:0071103 105 0.020
nucleus organization GO:0006997 45 0.020
purine nucleoside metabolic process GO:0042278 127 0.020
camera type eye development GO:0043010 4 0.020
negative regulation of transcription dna templated GO:0045892 237 0.020
regulation of cellular amine metabolic process GO:0033238 3 0.020
axon development GO:0061564 297 0.019
embryo development ending in birth or egg hatching GO:0009792 152 0.019
carbohydrate derivative catabolic process GO:1901136 118 0.019
positive regulation of gtp catabolic process GO:0033126 43 0.019
ribose phosphate metabolic process GO:0019693 145 0.019
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.019
cuticle pattern formation GO:0035017 27 0.019
stem cell differentiation GO:0048863 117 0.019
autophagy GO:0006914 108 0.019
positive regulation of response to stimulus GO:0048584 323 0.019
histone modification GO:0016570 106 0.019
oocyte axis specification GO:0007309 108 0.019
cell junction organization GO:0034330 57 0.019
epithelial cell differentiation GO:0030855 322 0.019
positive regulation of hydrolase activity GO:0051345 78 0.019
aromatic compound catabolic process GO:0019439 166 0.019
g2 dna damage checkpoint GO:0031572 69 0.019
negative regulation of homeostatic process GO:0032845 2 0.019
protein import into nucleus GO:0006606 51 0.019
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.018
anterior posterior pattern specification GO:0009952 136 0.018
heterocycle catabolic process GO:0046700 166 0.018
negative regulation of nucleic acid templated transcription GO:1903507 240 0.018
regulation of ras protein signal transduction GO:0046578 93 0.018
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.018
spindle organization GO:0007051 253 0.018
lipid metabolic process GO:0006629 121 0.017
spindle assembly involved in mitosis GO:0090307 50 0.017
neuron recognition GO:0008038 101 0.017
regulation of gene silencing GO:0060968 63 0.017
positive regulation of biosynthetic process GO:0009891 316 0.017
axonogenesis GO:0007409 290 0.017
establishment of mitotic spindle localization GO:0040001 17 0.017
chromatin organization GO:0006325 207 0.017
regulation of cell death GO:0010941 173 0.017
cell junction assembly GO:0034329 42 0.017
purine ribonucleoside catabolic process GO:0046130 112 0.017
ribonucleotide metabolic process GO:0009259 145 0.017
embryonic pattern specification GO:0009880 174 0.017
positive regulation of signal transduction GO:0009967 223 0.017
nucleoside phosphate catabolic process GO:1901292 110 0.017
mitotic cell cycle phase transition GO:0044772 138 0.016
regulation of catalytic activity GO:0050790 185 0.016
response to bacterium GO:0009617 198 0.016
dendrite guidance GO:0070983 21 0.016
lateral inhibition GO:0046331 206 0.016
tissue morphogenesis GO:0048729 297 0.016
dendrite development GO:0016358 204 0.016
glycosyl compound metabolic process GO:1901657 127 0.016
oviposition GO:0018991 19 0.016
protein transport GO:0015031 155 0.016
regulation of multi organism process GO:0043900 131 0.016
response to organic cyclic compound GO:0014070 89 0.016
positive regulation of ras gtpase activity GO:0032320 36 0.016
cell cell signaling involved in cell fate commitment GO:0045168 210 0.015
intracellular transport GO:0046907 228 0.015
oenocyte development GO:0007438 8 0.015
multi organism behavior GO:0051705 175 0.015
skeletal muscle organ development GO:0060538 48 0.015
signal transduction by phosphorylation GO:0023014 107 0.015
rna localization GO:0006403 115 0.015
purine ribonucleotide metabolic process GO:0009150 145 0.015
nucleotide catabolic process GO:0009166 109 0.015
nucleobase containing small molecule metabolic process GO:0055086 174 0.015
rhabdomere development GO:0042052 38 0.015
oxoacid metabolic process GO:0043436 103 0.015
positive regulation of rna biosynthetic process GO:1902680 266 0.015
gtp metabolic process GO:0046039 72 0.015
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.015
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.015
determination of ventral identity GO:0048264 1 0.014
organic acid metabolic process GO:0006082 103 0.014
establishment of localization in cell GO:0051649 402 0.014
nucleoside triphosphate catabolic process GO:0009143 108 0.014
regulation of alternative mrna splicing via spliceosome GO:0000381 60 0.014
positive regulation of rna metabolic process GO:0051254 271 0.014
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.014
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.014
dendrite morphogenesis GO:0048813 199 0.014
organophosphate metabolic process GO:0019637 195 0.014
response to nitrogen compound GO:1901698 90 0.014
stem cell development GO:0048864 79 0.014
regulation of system process GO:0044057 36 0.014
anterior posterior axis specification GO:0009948 109 0.014
cellular nitrogen compound catabolic process GO:0044270 165 0.014
ribonucleoside catabolic process GO:0042454 112 0.014
regulation of molecular function GO:0065009 217 0.014
negative regulation of cell cycle GO:0045786 116 0.014
segmentation GO:0035282 207 0.014
regulation of cellular catabolic process GO:0031329 157 0.014
nucleocytoplasmic transport GO:0006913 72 0.014
positive regulation of transport GO:0051050 92 0.014
pole plasm assembly GO:0007315 61 0.014
regulation of gtp catabolic process GO:0033124 44 0.013
positive regulation of intracellular transport GO:0032388 42 0.013
response to monosaccharide GO:0034284 4 0.013
negative regulation of response to stimulus GO:0048585 258 0.013
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.013
purine nucleotide metabolic process GO:0006163 146 0.013
ribonucleoside triphosphate metabolic process GO:0009199 119 0.013
carbohydrate metabolic process GO:0005975 82 0.013
organic substance transport GO:0071702 257 0.013
regulation of purine nucleotide metabolic process GO:1900542 62 0.013
regulation of cell division GO:0051302 72 0.013
regulation of chromosome organization GO:0033044 64 0.013
neural retina development GO:0003407 4 0.013
mitotic spindle organization GO:0007052 220 0.013
positive regulation of i kappab kinase nf kappab signaling GO:0043123 1 0.013
purine nucleoside triphosphate metabolic process GO:0009144 119 0.012
developmental maturation GO:0021700 172 0.012
programmed cell death GO:0012501 257 0.012
positive regulation of phosphorus metabolic process GO:0010562 139 0.012
regulation of transport GO:0051049 181 0.012
notch signaling pathway GO:0007219 120 0.012
neuron projection guidance GO:0097485 241 0.012
single organism cell adhesion GO:0098602 47 0.012
cytoplasmic transport GO:0016482 130 0.012
blastoderm segmentation GO:0007350 159 0.012
nucleoside catabolic process GO:0009164 112 0.012
small molecule metabolic process GO:0044281 305 0.012
positive regulation of cell communication GO:0010647 250 0.012
macromolecular complex assembly GO:0065003 256 0.012
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.012
regulation of autophagy GO:0010506 62 0.012
amine metabolic process GO:0009308 12 0.012
sensory organ morphogenesis GO:0090596 260 0.012
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.012
cellular response to dna damage stimulus GO:0006974 223 0.012
regulation of small gtpase mediated signal transduction GO:0051056 93 0.012
blood circulation GO:0008015 26 0.012
histone exchange GO:0043486 21 0.012
cellular amine metabolic process GO:0044106 12 0.012
oocyte anterior posterior axis specification GO:0007314 72 0.012
regulation of phosphorylation GO:0042325 147 0.012
defense response to bacterium GO:0042742 178 0.012
positive regulation of cellular catabolic process GO:0031331 95 0.012
regulation of response to stress GO:0080134 200 0.012
establishment or maintenance of cell polarity GO:0007163 167 0.012
positive regulation of cellular protein metabolic process GO:0032270 118 0.012
positive regulation of cell cycle GO:0045787 43 0.012
guanosine containing compound metabolic process GO:1901068 74 0.011
photoreceptor cell development GO:0042461 96 0.011
regulation of phosphate metabolic process GO:0019220 210 0.011
eggshell formation GO:0030703 105 0.011
negative regulation of protein export from nucleus GO:0046826 2 0.011
nucleotide metabolic process GO:0009117 161 0.011
ncrna metabolic process GO:0034660 43 0.011
ribonucleoside metabolic process GO:0009119 127 0.011
embryonic morphogenesis GO:0048598 206 0.011
positive regulation of signaling GO:0023056 243 0.011
positive regulation of intracellular signal transduction GO:1902533 116 0.011
pigment metabolic process GO:0042440 84 0.011
nuclear transport GO:0051169 72 0.011
central nervous system development GO:0007417 201 0.011
cell adhesion GO:0007155 136 0.011
positive regulation of nucleotide catabolic process GO:0030813 46 0.011
purine ribonucleoside metabolic process GO:0046128 127 0.011
cellular response to organic substance GO:0071310 132 0.011
centrosome organization GO:0051297 163 0.011
cell death GO:0008219 279 0.011
positive regulation of neurogenesis GO:0050769 41 0.011
regulation of nucleotide metabolic process GO:0006140 62 0.010
organic cyclic compound catabolic process GO:1901361 168 0.010
dna packaging GO:0006323 91 0.010
imaginal disc derived wing morphogenesis GO:0007476 337 0.010
positive regulation of phosphorylation GO:0042327 87 0.010
positive regulation of gene expression GO:0010628 290 0.010
regulation of protein localization GO:0032880 76 0.010
carbohydrate derivative metabolic process GO:1901135 217 0.010
reproductive system development GO:0061458 74 0.010
enzyme linked receptor protein signaling pathway GO:0007167 179 0.010
mitotic cytokinesis GO:0000281 50 0.010
ncrna processing GO:0034470 30 0.010
response to organic substance GO:0010033 284 0.010
neuroblast proliferation GO:0007405 74 0.010
cardiovascular system development GO:0072358 82 0.010

TH1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.057
muscular disease DOID:0080000 0 0.018
musculoskeletal system disease DOID:17 0 0.018
muscle tissue disease DOID:66 0 0.018