Homo sapiens

58 known processes

SEC61B

Sec61 beta subunit

SEC61B biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
mitochondrial calcium ion homeostasis GO:0051560 11 0.793
post embryonic development GO:0009791 2 0.375
female gamete generation GO:0007292 2 0.151
protein localization to endoplasmic reticulum GO:0070972 19 0.150
protein localization to organelle GO:0033365 280 0.130
oogenesis GO:0048477 2 0.130
calcium mediated signaling using intracellular calcium source GO:0035584 7 0.114
positive regulation of mitochondrial calcium ion concentration GO:0051561 8 0.111
cytoplasmic transport GO:0016482 379 0.087
cellular amino acid metabolic process GO:0006520 116 0.076
cellular metal ion homeostasis GO:0006875 146 0.075
vesicle mediated transport GO:0016192 371 0.075
establishment of protein localization to organelle GO:0072594 172 0.073
endoplasmic reticulum organization GO:0007029 20 0.073
negative regulation of endoplasmic reticulum calcium ion concentration GO:0032471 6 0.061
modification dependent protein catabolic process GO:0019941 209 0.061
oocyte differentiation GO:0009994 2 0.060
metal ion homeostasis GO:0055065 169 0.059
membrane organization GO:0061024 292 0.056
cellular response to organic cyclic compound GO:0071407 127 0.055
transmembrane transport GO:0055085 399 0.054
protein glycosylation GO:0006486 62 0.054
intracellular protein transport GO:0006886 270 0.053
determination of adult lifespan GO:0008340 2 0.052
positive regulation of hydrolase activity GO:0051345 331 0.050
cytosolic calcium ion homeostasis GO:0051480 89 0.050
ubiquitin dependent protein catabolic process GO:0006511 206 0.049
er associated ubiquitin dependent protein catabolic process GO:0030433 31 0.048
autophagy GO:0006914 88 0.048
protein localization to membrane GO:0072657 160 0.048
oocyte development GO:0048599 1 0.047
modification dependent macromolecule catabolic process GO:0043632 212 0.047
purine nucleoside triphosphate metabolic process GO:0009144 412 0.047
glycoprotein metabolic process GO:0009100 110 0.046
single organism carbohydrate metabolic process GO:0044723 193 0.046
single organism membrane organization GO:0044802 268 0.044
purine nucleoside catabolic process GO:0006152 398 0.044
calcium ion homeostasis GO:0055074 122 0.044
purine ribonucleoside catabolic process GO:0046130 398 0.042
regulation of cellular amino acid metabolic process GO:0006521 6 0.042
cellular macromolecule catabolic process GO:0044265 380 0.042
chemical homeostasis GO:0048878 306 0.041
cellular cation homeostasis GO:0030003 163 0.041
ribonucleoside catabolic process GO:0042454 406 0.041
response to estrogen GO:0043627 47 0.041
positive regulation of cellular component organization GO:0051130 376 0.040
amine metabolic process GO:0009308 44 0.040
cellular response to endogenous stimulus GO:0071495 336 0.040
response to other organism GO:0051707 261 0.040
cellular ketone metabolic process GO:0042180 80 0.040
cellular amine metabolic process GO:0044106 41 0.039
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.038
cation homeostasis GO:0055080 189 0.038
purine ribonucleotide catabolic process GO:0009154 404 0.038
single organism cellular localization GO:1902580 332 0.038
ribonucleotide catabolic process GO:0009261 405 0.038
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.038
carbohydrate derivative biosynthetic process GO:1901137 207 0.037
ribonucleoside triphosphate catabolic process GO:0009203 391 0.037
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.036
second messenger mediated signaling GO:0019932 78 0.036
nucleoside catabolic process GO:0009164 408 0.036
purine nucleotide catabolic process GO:0006195 405 0.036
cellular homeostasis GO:0019725 196 0.036
single organism reproductive process GO:0044702 98 0.035
immune response GO:0006955 307 0.035
cellular response to hormone stimulus GO:0032870 125 0.035
multicellular organismal aging GO:0010259 3 0.034
carbohydrate metabolic process GO:0005975 207 0.034
positive regulation of cellular amine metabolic process GO:0033240 7 0.034
cellular ion homeostasis GO:0006873 168 0.034
glycosyl compound catabolic process GO:1901658 413 0.034
rna interference GO:0016246 4 0.034
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.034
cellular component morphogenesis GO:0032989 314 0.034
protein targeting GO:0006605 187 0.033
cellular protein catabolic process GO:0044257 261 0.033
purine ribonucleoside metabolic process GO:0046128 437 0.032
nervous system development GO:0007399 293 0.032
negative regulation of protein metabolic process GO:0051248 391 0.032
regulation of cellular ketone metabolic process GO:0010565 50 0.032
nucleoside phosphate catabolic process GO:1901292 412 0.031
cellular calcium ion homeostasis GO:0006874 117 0.030
guanosine containing compound metabolic process GO:1901068 244 0.030
response to organic cyclic compound GO:0014070 204 0.029
embryo development GO:0009790 123 0.029
cell growth GO:0016049 160 0.029
mitotic cell cycle GO:0000278 326 0.028
regulation of cellular component movement GO:0051270 334 0.028
cell development GO:0048468 328 0.028
positive regulation of organelle organization GO:0010638 195 0.027
positive regulation of transport GO:0051050 336 0.027
morphogenesis of embryonic epithelium GO:0016331 4 0.027
growth GO:0040007 202 0.027
guanosine containing compound catabolic process GO:1901069 239 0.027
ribonucleoside triphosphate metabolic process GO:0009199 412 0.026
reactive oxygen species metabolic process GO:0072593 75 0.026
small gtpase mediated signal transduction GO:0007264 78 0.026
hindbrain development GO:0030902 3 0.025
endomembrane system organization GO:0010256 196 0.025
purine containing compound catabolic process GO:0072523 411 0.025
regulation of cellular amine metabolic process GO:0033238 11 0.025
positive regulation of cytosolic calcium ion concentration GO:0007204 82 0.025
microtubule based process GO:0007017 210 0.025
response to lipid GO:0033993 206 0.025
ossification GO:0001503 121 0.025
response to steroid hormone GO:0048545 80 0.025
positive regulation of programmed cell death GO:0043068 249 0.025
golgi vesicle transport GO:0048193 80 0.024
cellular chemical homeostasis GO:0055082 180 0.024
cellular response to dna damage stimulus GO:0006974 379 0.024
response to hormone GO:0009725 175 0.024
nucleotide catabolic process GO:0009166 408 0.024
calcium mediated signaling GO:0019722 44 0.023
regulation of intracellular transport GO:0032386 195 0.023
compound eye development GO:0048749 1 0.023
osteoblast differentiation GO:0001649 92 0.023
purine nucleoside triphosphate catabolic process GO:0009146 392 0.023
regulation of hormone levels GO:0010817 125 0.023
regulation of peptidase activity GO:0052547 180 0.023
divalent inorganic cation homeostasis GO:0072507 136 0.023
secretion by cell GO:0032940 226 0.022
regulation of proteolysis GO:0030162 293 0.022
regulation of anatomical structure morphogenesis GO:0022603 286 0.022
regulation of protein localization GO:0032880 296 0.022
protein targeting to membrane GO:0006612 42 0.021
nitrogen compound transport GO:0071705 191 0.021
response to drug GO:0042493 81 0.021
protein catabolic process GO:0030163 325 0.021
nucleoside triphosphate catabolic process GO:0009143 394 0.021
response to bacterium GO:0009617 144 0.020
ion homeostasis GO:0050801 230 0.020
response to metal ion GO:0010038 84 0.020
positive regulation of phosphorylation GO:0042327 394 0.020
cellular divalent inorganic cation homeostasis GO:0072503 128 0.020
photoreceptor cell differentiation GO:0046530 2 0.020
neurogenesis GO:0022008 169 0.020
positive regulation of cellular catabolic process GO:0031331 284 0.020
reproductive process GO:0022414 106 0.020
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.019
response to biotic stimulus GO:0009607 276 0.019
intracellular protein transmembrane transport GO:0065002 24 0.019
mitotic cell cycle process GO:1903047 286 0.019
negative regulation of programmed cell death GO:0043069 321 0.019
protein maturation GO:0051604 233 0.019
cellular response to external stimulus GO:0071496 111 0.019
nucleoside triphosphate metabolic process GO:0009141 422 0.019
gtp catabolic process GO:0006184 237 0.019
negative regulation of cellular protein metabolic process GO:0032269 353 0.019
enzyme linked receptor protein signaling pathway GO:0007167 303 0.019
cellular response to lipid GO:0071396 127 0.018
negative regulation of catabolic process GO:0009895 104 0.018
positive regulation of cellular component movement GO:0051272 181 0.018
negative regulation of apoptotic process GO:0043066 316 0.018
response to external biotic stimulus GO:0043207 261 0.018
positive regulation of proteolysis GO:0045862 142 0.018
mitochondrion organization GO:0007005 156 0.018
regulation of transferase activity GO:0051338 355 0.018
cellular response to growth factor stimulus GO:0071363 197 0.018
negative regulation of catalytic activity GO:0043086 335 0.018
regulation of endopeptidase activity GO:0052548 170 0.018
apoptotic signaling pathway GO:0097190 268 0.017
microtubule cytoskeleton organization GO:0000226 176 0.017
positive regulation of cell death GO:0010942 263 0.017
response to inorganic substance GO:0010035 127 0.017
negative regulation of cell death GO:0060548 345 0.017
regulation of nucleotide metabolic process GO:0006140 269 0.017
molting cycle GO:0042303 28 0.017
maintenance of location GO:0051235 112 0.017
secretion GO:0046903 254 0.017
negative regulation of phosphorus metabolic process GO:0010563 267 0.017
epithelium development GO:0060429 227 0.016
segmentation GO:0035282 4 0.016
organophosphate catabolic process GO:0046434 430 0.016
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.016
negative regulation of cellular component organization GO:0051129 235 0.016
response to abiotic stimulus GO:0009628 336 0.016
mrna metabolic process GO:0016071 175 0.016
macromolecule glycosylation GO:0043413 63 0.016
regulation of cellular component biogenesis GO:0044087 281 0.016
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.016
regulation of apoptotic signaling pathway GO:2001233 175 0.015
positive regulation of cell proliferation GO:0008284 301 0.015
system process GO:0003008 349 0.015
negative regulation of phosphate metabolic process GO:0045936 267 0.015
epithelium migration GO:0090132 119 0.015
regulation of purine nucleotide metabolic process GO:1900542 264 0.015
ameboidal type cell migration GO:0001667 135 0.015
regulation of purine nucleotide catabolic process GO:0033121 205 0.015
spermatid differentiation GO:0048515 4 0.015
positive regulation of cell motility GO:2000147 177 0.015
cellular macromolecular complex assembly GO:0034622 324 0.015
posttranscriptional regulation of gene expression GO:0010608 213 0.015
cellular response to toxic substance GO:0097237 4 0.015
positive regulation of locomotion GO:0040017 186 0.015
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.015
regulation of autophagy GO:0010506 52 0.015
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.015
regulation of locomotion GO:0040012 329 0.015
thyroid hormone transport GO:0070327 2 0.015
rna processing GO:0006396 255 0.015
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.015
establishment of protein localization to membrane GO:0090150 121 0.014
endocytosis GO:0006897 159 0.014
tissue morphogenesis GO:0048729 96 0.014
regulation of protein transport GO:0051223 213 0.014
ras protein signal transduction GO:0007265 73 0.014
regulation of cell cycle GO:0051726 393 0.014
response to oxygen containing compound GO:1901700 369 0.014
cytokinesis GO:0000910 96 0.014
defense response GO:0006952 315 0.014
membrane budding GO:0006900 28 0.014
tissue migration GO:0090130 119 0.014
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.014
regulation of kinase activity GO:0043549 314 0.014
positive regulation of developmental process GO:0051094 314 0.014
anatomical structure formation involved in morphogenesis GO:0048646 284 0.014
regulation of cell cycle process GO:0010564 266 0.014
cellular response to steroid hormone stimulus GO:0071383 37 0.014
positive regulation of kinase activity GO:0033674 204 0.014
cell adhesion GO:0007155 325 0.014
regulation of cell differentiation GO:0045595 393 0.013
protein localization to nucleus GO:0034504 136 0.013
positive regulation of organ growth GO:0046622 2 0.013
protein import GO:0017038 130 0.013
epithelial cell migration GO:0010631 119 0.013
cell division GO:0051301 168 0.013
positive regulation of peptidase activity GO:0010952 88 0.013
response to unfolded protein GO:0006986 24 0.013
positive regulation of apoptotic process GO:0043065 246 0.013
response to growth factor GO:0070848 205 0.013
biological adhesion GO:0022610 331 0.013
blastocyst development GO:0001824 3 0.013
spermatid development GO:0007286 4 0.013
gtp metabolic process GO:0046039 239 0.013
positive regulation of cell migration GO:0030335 172 0.013
eye photoreceptor cell differentiation GO:0001754 2 0.013
regulation of actin filament based process GO:0032970 141 0.013
regulation of protein complex assembly GO:0043254 147 0.013
positive regulation of nucleoside metabolic process GO:0045979 186 0.013
regulation of meiotic cell cycle GO:0051445 4 0.013
regulation of cell morphogenesis GO:0022604 153 0.013
positive regulation of nucleotide metabolic process GO:0045981 230 0.013
tube development GO:0035295 125 0.013
positive regulation of nucleotide catabolic process GO:0030813 185 0.013
neuromuscular junction development GO:0007528 3 0.013
embryonic epithelial tube formation GO:0001838 4 0.012
response to nutrient levels GO:0031667 81 0.012
positive regulation of apoptotic signaling pathway GO:2001235 70 0.012
positive regulation of intrinsic apoptotic signaling pathway GO:2001244 28 0.012
regulation of cellular response to stress GO:0080135 244 0.012
negative regulation of cellular catabolic process GO:0031330 83 0.012
multi organism reproductive process GO:0044703 54 0.012
metal ion transport GO:0030001 272 0.012
positive regulation of cell differentiation GO:0045597 211 0.012
response to extracellular stimulus GO:0009991 85 0.012
cellular response to nutrient levels GO:0031669 69 0.012
regulation of cell migration GO:0030334 289 0.012
positive regulation of cysteine type endopeptidase activity GO:2001056 79 0.012
signal transduction by phosphorylation GO:0023014 297 0.012
innate immune response GO:0045087 178 0.012
regulation of multi organism process GO:0043900 157 0.012
cellular response to estrogen stimulus GO:0071391 16 0.012
developmental growth GO:0048589 48 0.012
skeletal system development GO:0001501 79 0.012
actin filament based process GO:0030029 224 0.012
actin mediated cell contraction GO:0070252 12 0.012
cellular response to starvation GO:0009267 58 0.012
locomotory behavior GO:0007626 1 0.012
regulation of cysteine type endopeptidase activity GO:2000116 127 0.012
protein oligomerization GO:0051259 173 0.012
monocarboxylic acid metabolic process GO:0032787 185 0.012
cell projection organization GO:0030030 252 0.012
proteasomal protein catabolic process GO:0010498 176 0.012
actin cytoskeleton organization GO:0030036 207 0.012
positive regulation of gtp catabolic process GO:0033126 166 0.012
extrinsic apoptotic signaling pathway GO:0097191 119 0.011
response to nitrogen compound GO:1901698 184 0.011
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.011
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 69 0.011
mapk cascade GO:0000165 288 0.011
establishment of organelle localization GO:0051656 59 0.011
positive regulation of catabolic process GO:0009896 310 0.011
negative regulation of phosphorylation GO:0042326 174 0.011
positive regulation of protein kinase activity GO:0045860 190 0.011
multicellular organismal homeostasis GO:0048871 67 0.011
chronological cell aging GO:0001300 2 0.011
positive regulation of cellular component biogenesis GO:0044089 158 0.011
generation of neurons GO:0048699 152 0.011
regulation of establishment of protein localization GO:0070201 242 0.011
mitotic spindle elongation GO:0000022 4 0.011
engulfment of apoptotic cell GO:0043652 2 0.011
response to radiation GO:0009314 151 0.011
positive regulation of protein phosphorylation GO:0001934 313 0.011
intrinsic apoptotic signaling pathway GO:0097193 127 0.011
regulation of metal ion transport GO:0010959 120 0.011
regulation of protein processing GO:0070613 150 0.011
organic hydroxy compound metabolic process GO:1901615 147 0.011
reactive nitrogen species metabolic process GO:2001057 3 0.011
regulation of actin filament length GO:0030832 56 0.011
macroautophagy GO:0016236 39 0.011
response to lipopolysaccharide GO:0032496 70 0.011
regulation of intrinsic apoptotic signaling pathway GO:2001242 72 0.011
regulation of ras protein signal transduction GO:0046578 155 0.011
blastoderm segmentation GO:0007350 2 0.011
positive regulation of transferase activity GO:0051347 227 0.011
positive regulation of immune system process GO:0002684 283 0.011
positive regulation of blood pressure GO:0045777 3 0.011
mrna processing GO:0006397 133 0.011
regulation of response to external stimulus GO:0032101 222 0.010
cardiac muscle cell contraction GO:0086003 4 0.010
regulation of reactive oxygen species metabolic process GO:2000377 41 0.010
protein homooligomerization GO:0051260 100 0.010
regulation of binding GO:0051098 111 0.010
negative regulation of multicellular organismal process GO:0051241 317 0.010
regeneration GO:0031099 4 0.010
apoptotic mitochondrial changes GO:0008637 57 0.010
regulation of branching involved in ureteric bud morphogenesis GO:0090189 3 0.010
regulation of intracellular protein transport GO:0033157 123 0.010
response to fungus GO:0009620 4 0.010
cellular response to cytokine stimulus GO:0071345 181 0.010
cellular response to extracellular stimulus GO:0031668 72 0.010

SEC61B disease predictions

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 167 0.026
disease of cellular proliferation DOID:14566 174 0.026
musculoskeletal system disease DOID:17 223 0.016
disease of metabolism DOID:0014667 295 0.016
organ system cancer DOID:0050686 164 0.015
inherited metabolic disorder DOID:655 242 0.014
sensory system disease DOID:0050155 203 0.014
eye and adnexa disease DOID:1492 150 0.014
nervous system disease DOID:863 431 0.014
eye disease DOID:5614 149 0.014
connective tissue disease DOID:65 109 0.011
retinal disease DOID:5679 118 0.010