Homo sapiens

5 known processes

LAMP2

lysosomal-associated membrane protein 2

(Aliases: LGP110,LAMPB,CD107b)

LAMP2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
negative regulation of glycoprotein metabolic process GO:1903019 8 0.502
glycoprotein metabolic process GO:0009100 110 0.411
eye pigmentation GO:0048069 1 0.398
positive regulation of transport GO:0051050 336 0.388
Human
blood vessel development GO:0001568 172 0.268
endosomal transport GO:0016197 129 0.249
lipid transport GO:0006869 90 0.245
lysosomal transport GO:0007041 33 0.232
Human
amyloid precursor protein metabolic process GO:0042982 17 0.229
membrane organization GO:0061024 292 0.214
secretion by cell GO:0032940 226 0.196
Human
endosome to lysosome transport GO:0008333 21 0.181
blood vessel morphogenesis GO:0048514 162 0.177
vesicle mediated transport GO:0016192 371 0.177
Human
vacuolar transport GO:0007034 34 0.168
Human
intracellular protein transport GO:0006886 270 0.162
determination of adult lifespan GO:0008340 2 0.156
cellular amide metabolic process GO:0043603 69 0.154
signal transduction by phosphorylation GO:0023014 297 0.150
apoptotic signaling pathway GO:0097190 268 0.136
Human
regulation of secretion GO:0051046 194 0.135
Human
regulation of protein localization GO:0032880 296 0.133
post golgi vesicle mediated transport GO:0006892 36 0.132
Human
innate immune response GO:0045087 178 0.130
Human
angiogenesis GO:0001525 147 0.128
cytoplasmic transport GO:0016482 379 0.126
Human
secretion GO:0046903 254 0.121
Human
positive regulation of secretion GO:0051047 116 0.109
Human
regulation of amyloid precursor protein biosynthetic process GO:0042984 4 0.106
immune effector process GO:0002252 159 0.103
Human
positive regulation of exocytosis GO:0045921 35 0.100
Human
single organism membrane organization GO:0044802 268 0.089
female gamete generation GO:0007292 2 0.088
regulation of intracellular transport GO:0032386 195 0.086
Human
cholesterol transport GO:0030301 39 0.084
alcohol metabolic process GO:0006066 114 0.083
regulation of systemic arterial blood pressure by circulatory renin angiotensin GO:0001991 4 0.082
golgi vesicle transport GO:0048193 80 0.082
Human
phospholipid translocation GO:0045332 2 0.073
mapk cascade GO:0000165 288 0.073
regulation of glycoprotein metabolic process GO:1903018 19 0.073
establishment of tissue polarity GO:0007164 3 0.070
purine nucleoside triphosphate metabolic process GO:0009144 412 0.070
cellular homeostasis GO:0019725 196 0.070
lipid metabolic process GO:0006629 381 0.068
peptide metabolic process GO:0006518 51 0.065
purine ribonucleoside metabolic process GO:0046128 437 0.063
steroid metabolic process GO:0008202 94 0.061
exocytosis GO:0006887 71 0.059
Human
negative regulation of glycoprotein biosynthetic process GO:0010561 5 0.059
organophosphate biosynthetic process GO:0090407 163 0.058
negative regulation of multicellular organismal process GO:0051241 317 0.058
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.057
positive regulation of hydrolase activity GO:0051345 331 0.057
glycoprotein biosynthetic process GO:0009101 91 0.055
regulation of cellular component movement GO:0051270 334 0.054
Human
regulation of peptidase activity GO:0052547 180 0.054
transition metal ion transport GO:0000041 23 0.052
positive regulation of wnt signaling pathway GO:0030177 54 0.051
ribonucleotide catabolic process GO:0009261 405 0.051
anatomical structure formation involved in morphogenesis GO:0048646 284 0.051
nucleoside triphosphate catabolic process GO:0009143 394 0.050
immune response GO:0006955 307 0.049
Human
response to oxidative stress GO:0006979 121 0.049
organic hydroxy compound metabolic process GO:1901615 147 0.049
sphingolipid metabolic process GO:0006665 38 0.048
negative regulation of transport GO:0051051 176 0.047
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.046
positive regulation of catabolic process GO:0009896 310 0.045
single organism cellular localization GO:1902580 332 0.044
post embryonic development GO:0009791 2 0.043
protein stabilization GO:0050821 64 0.043
Mouse
regulation of mapk cascade GO:0043408 262 0.043
organic anion transport GO:0015711 103 0.041
endomembrane system organization GO:0010256 196 0.041
amyloid precursor protein biosynthetic process GO:0042983 4 0.040
wnt signaling pathway GO:0016055 156 0.040
regulation of blood pressure GO:0008217 30 0.039
regulation of vesicle mediated transport GO:0060627 130 0.039
Human
regulation of systemic arterial blood pressure mediated by a chemical signal GO:0003044 12 0.038
circulatory system development GO:0072359 262 0.038
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 89 0.037
positive regulation of cell migration GO:0030335 172 0.037
protein localization to organelle GO:0033365 280 0.037
Human
lipid localization GO:0010876 106 0.037
monovalent inorganic cation transport GO:0015672 128 0.036
regulation of establishment of protein localization GO:0070201 242 0.035
calcium ion homeostasis GO:0055074 122 0.035
positive regulation of intracellular transport GO:0032388 104 0.035
regulation of cytokine production GO:0001817 232 0.034
c21 steroid hormone biosynthetic process GO:0006700 11 0.034
cellular hormone metabolic process GO:0034754 41 0.033
negative regulation of protein transport GO:0051224 75 0.033
negative regulation of secretion GO:0051048 58 0.031
regulation of locomotion GO:0040012 329 0.031
lysosome organization GO:0007040 24 0.031
small molecule biosynthetic process GO:0044283 157 0.031
regulation of autophagy GO:0010506 52 0.031
anion transport GO:0006820 161 0.031
regulation of wnt signaling pathway GO:0030111 123 0.031
anatomical structure homeostasis GO:0060249 100 0.030
membrane lipid metabolic process GO:0006643 53 0.030
regulation of defense response GO:0031347 154 0.030
Human
protein localization to membrane GO:0072657 160 0.030
hormone metabolic process GO:0042445 61 0.030
autophagy GO:0006914 88 0.029
positive regulation of protein catabolic process GO:0045732 75 0.029
cellular lipid metabolic process GO:0044255 303 0.029
inorganic cation transmembrane transport GO:0098662 194 0.029
purine containing compound catabolic process GO:0072523 411 0.029
negative regulation of cellular component organization GO:0051129 235 0.028
regulation of multi organism process GO:0043900 157 0.028
biological adhesion GO:0022610 331 0.028
lymphocyte mediated immunity GO:0002449 48 0.027
Human
regulation of nucleotide metabolic process GO:0006140 269 0.027
positive regulation of immune system process GO:0002684 283 0.026
Human
defense response GO:0006952 315 0.026
Human
cellular amino acid metabolic process GO:0006520 116 0.026
positive regulation of cell proliferation GO:0008284 301 0.026
response to bacterium GO:0009617 144 0.025
positive regulation of phosphorylation GO:0042327 394 0.025
guanosine containing compound metabolic process GO:1901068 244 0.025
cellular metal ion homeostasis GO:0006875 146 0.025
positive regulation of cellular catabolic process GO:0031331 284 0.025
single organism cell adhesion GO:0098602 179 0.024
ion transmembrane transport GO:0034220 338 0.024
negative regulation of protein metabolic process GO:0051248 391 0.024
viral process GO:0016032 146 0.023
posttranscriptional regulation of gene expression GO:0010608 213 0.023
Mouse
purine ribonucleotide catabolic process GO:0009154 404 0.023
regulation of gtpase activity GO:0043087 180 0.023
oogenesis GO:0048477 2 0.023
vesicle organization GO:0016050 62 0.023
transmembrane transport GO:0055085 399 0.023
negative regulation of amyloid precursor protein biosynthetic process GO:0042985 2 0.022
nucleoside triphosphate metabolic process GO:0009141 422 0.022
positive regulation of gtpase activity GO:0043547 166 0.022
cellular ion homeostasis GO:0006873 168 0.021
cellular response to growth factor stimulus GO:0071363 197 0.021
organelle fusion GO:0048284 36 0.021
negative regulation of developmental process GO:0051093 247 0.021
ceramide metabolic process GO:0006672 25 0.021
regulation of purine nucleotide metabolic process GO:1900542 264 0.021
positive regulation of keratinocyte migration GO:0051549 4 0.021
divalent inorganic cation homeostasis GO:0072507 136 0.021
regulation of keratinocyte migration GO:0051547 4 0.020
nucleoside catabolic process GO:0009164 408 0.020
establishment of protein localization to membrane GO:0090150 121 0.020
lipid translocation GO:0034204 2 0.020
vasculature development GO:0001944 181 0.020
lipid biosynthetic process GO:0008610 177 0.020
regulation of transforming growth factor beta1 production GO:0032908 3 0.019
transforming growth factor beta1 production GO:0032905 3 0.019
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 69 0.019
cellular divalent inorganic cation homeostasis GO:0072503 128 0.019
cell growth GO:0016049 160 0.019
cellular response to endogenous stimulus GO:0071495 336 0.019
regulation of angiotensin levels in blood GO:0002002 3 0.019
regulation of exocytosis GO:0017157 46 0.019
Human
protein secretion GO:0009306 98 0.019
phospholipid metabolic process GO:0006644 99 0.019
locomotory behavior GO:0007626 1 0.019
cellular cation homeostasis GO:0030003 163 0.019
positive regulation of secretion by cell GO:1903532 108 0.019
Human
regulation of immune response GO:0050776 201 0.019
Human
regulation of protein catabolic process GO:0042176 155 0.019
cell activation GO:0001775 213 0.019
Human
purine nucleoside catabolic process GO:0006152 398 0.018
purine nucleotide catabolic process GO:0006195 405 0.018
inorganic ion transmembrane transport GO:0098660 231 0.018
nucleoside phosphate catabolic process GO:1901292 412 0.018
regulation of cell motility GO:2000145 299 0.018
response to reactive oxygen species GO:0000302 61 0.018
cardiovascular system development GO:0072358 262 0.018
negative regulation of nf kappab transcription factor activity GO:0032088 51 0.018
alcohol biosynthetic process GO:0046165 52 0.018
negative regulation of multi organism process GO:0043901 92 0.017
cellular component morphogenesis GO:0032989 314 0.017
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 22 0.017
positive regulation of cellular component organization GO:0051130 376 0.017
neutrophil mediated immunity GO:0002446 4 0.017
protein localization to plasma membrane GO:0072659 93 0.017
cell morphogenesis involved in differentiation GO:0000904 144 0.017
regulation of anatomical structure morphogenesis GO:0022603 286 0.017
regulation of proteolysis GO:0030162 293 0.017
ribonucleoside catabolic process GO:0042454 406 0.017
response to hormone GO:0009725 175 0.017
vacuole organization GO:0007033 44 0.017
guanosine containing compound catabolic process GO:1901069 239 0.017
cellular response to oxidative stress GO:0034599 85 0.016
cellular response to glucocorticoid stimulus GO:0071385 4 0.016
gtp catabolic process GO:0006184 237 0.016
regulation of secretion by cell GO:1903530 177 0.016
Human
negative regulation of peptidase activity GO:0010466 91 0.016
bmp signaling pathway GO:0030509 49 0.016
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.016
small gtpase mediated signal transduction GO:0007264 78 0.016
metal ion homeostasis GO:0055065 169 0.016
regulation of angiotensin metabolic process GO:0060177 3 0.016
cation transmembrane transport GO:0098655 238 0.016
organophosphate catabolic process GO:0046434 430 0.016
regulation of transferase activity GO:0051338 355 0.016
eosinophil mediated immunity GO:0002447 2 0.016
regulation of protein maturation GO:1903317 150 0.015
negative regulation of cellular response to growth factor stimulus GO:0090288 41 0.015
regulation of protein secretion GO:0050708 86 0.015
purine ribonucleoside catabolic process GO:0046130 398 0.015
response to wounding GO:0009611 168 0.015
ribonucleoside triphosphate catabolic process GO:0009203 391 0.015
establishment of planar polarity GO:0001736 3 0.015
neuron projection development GO:0031175 106 0.015
purine nucleoside triphosphate catabolic process GO:0009146 392 0.014
positive regulation of endopeptidase activity GO:0010950 84 0.014
cell death in response to oxidative stress GO:0036473 29 0.014
chemical homeostasis GO:0048878 306 0.014
morphogenesis of a polarized epithelium GO:0001738 3 0.014
negative regulation of blood vessel morphogenesis GO:2000181 41 0.014
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.014
regulation of endopeptidase activity GO:0052548 170 0.014
transition metal ion homeostasis GO:0055076 31 0.014
cholesterol efflux GO:0033344 28 0.014
actin filament based process GO:0030029 224 0.014
growth GO:0040007 202 0.014
cellular response to external stimulus GO:0071496 111 0.014
negative regulation of intracellular signal transduction GO:1902532 183 0.014
cell development GO:0048468 328 0.014
positive regulation of nucleoside metabolic process GO:0045979 186 0.014
blastoderm segmentation GO:0007350 2 0.014
cell morphogenesis GO:0000902 296 0.014
response to biotic stimulus GO:0009607 276 0.013
protein catabolic process GO:0030163 325 0.013
gtp metabolic process GO:0046039 239 0.013
cell projection organization GO:0030030 252 0.013
neutrophil degranulation GO:0043312 3 0.013
membrane fusion GO:0061025 43 0.013
cellular response to oxygen containing compound GO:1901701 276 0.013
ras protein signal transduction GO:0007265 73 0.013
negative regulation of hydrolase activity GO:0051346 182 0.013
cation homeostasis GO:0055080 189 0.013
carbohydrate derivative biosynthetic process GO:1901137 207 0.013
protein modification by small protein conjugation GO:0032446 342 0.013
extrinsic apoptotic signaling pathway GO:0097191 119 0.013
regulation of interleukin 8 production GO:0032677 49 0.013
negative regulation of jak stat cascade GO:0046426 4 0.013
epithelial cell differentiation GO:0030855 141 0.013
cellular sodium ion homeostasis GO:0006883 8 0.013
multicellular organismal aging GO:0010259 3 0.013
negative regulation of locomotion GO:0040013 118 0.013
cellular response to hormone stimulus GO:0032870 125 0.013
establishment of protein localization to organelle GO:0072594 172 0.013
Human
early endosome to late endosome transport GO:0045022 21 0.013
nervous system development GO:0007399 293 0.013
regulation of systemic arterial blood pressure by hormone GO:0001990 12 0.013
maintenance of location GO:0051235 112 0.012
multi organism cellular process GO:0044764 156 0.012
regulation of purine nucleotide catabolic process GO:0033121 205 0.012
positive regulation of protein transport GO:0051222 135 0.012
negative regulation of fibroblast growth factor receptor signaling pathway GO:0040037 2 0.012
sterol transport GO:0015918 39 0.012
regulation of syncytium formation by plasma membrane fusion GO:0060142 2 0.012
system process GO:0003008 349 0.012
regulation of lipid biosynthetic process GO:0046890 47 0.012
neuromuscular junction development GO:0007528 3 0.012
negative regulation of cell motility GO:2000146 104 0.012
positive regulation of proteolysis GO:0045862 142 0.012
protein targeting GO:0006605 187 0.011
negative regulation of cell differentiation GO:0045596 171 0.011
negative regulation of cell death GO:0060548 345 0.011
sulfur compound metabolic process GO:0006790 101 0.011
response to salt stress GO:0009651 3 0.011
lipid catabolic process GO:0016042 84 0.011
intrinsic apoptotic signaling pathway GO:0097193 127 0.011
response to hypoxia GO:0001666 96 0.011
regulation of nucleoside metabolic process GO:0009118 209 0.011
tissue regeneration GO:0042246 3 0.011
negative regulation of protein maturation GO:1903318 142 0.011
regulation of neuron projection development GO:0010975 57 0.011
regulation of apoptotic signaling pathway GO:2001233 175 0.011
cell adhesion GO:0007155 325 0.011
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.011
mitochondrion organization GO:0007005 156 0.011
regulation of protein localization to plasma membrane GO:1903076 40 0.011
organophosphate ester transport GO:0015748 32 0.011
positive regulation of nucleotide catabolic process GO:0030813 185 0.011
cellular chemical homeostasis GO:0055082 180 0.011
regulation of cell shape GO:0008360 48 0.011
regulation of protein transport GO:0051223 213 0.011
circulatory system process GO:0003013 113 0.011
osteoclast development GO:0036035 2 0.011
regulation of intracellular protein transport GO:0033157 123 0.011
cellular response to fibroblast growth factor stimulus GO:0044344 39 0.011
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 109 0.010
epithelial cell proliferation GO:0050673 128 0.010
negative regulation of cell cycle GO:0045786 193 0.010
protein autoubiquitination GO:0051865 37 0.010
neuron development GO:0048666 113 0.010
myeloid cell differentiation GO:0030099 117 0.010
regulation of cellular response to growth factor stimulus GO:0090287 76 0.010
positive regulation of cell motility GO:2000147 177 0.010
response to other organism GO:0051707 261 0.010
negative regulation of apoptotic process GO:0043066 316 0.010
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.010
polyol metabolic process GO:0019751 32 0.010
protein maturation GO:0051604 233 0.010
peripheral nervous system development GO:0007422 2 0.010

LAMP2 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.986
inherited metabolic disorder DOID:655 242 0.986
lysosomal storage disease DOID:3211 47 0.964
lipid storage disease DOID:9455 28 0.606
mucopolysaccharidosis DOID:12798 11 0.114
central nervous system disease DOID:331 186 0.107
brain disease DOID:936 73 0.107
nervous system disease DOID:863 431 0.107
epilepsy syndrome DOID:1826 41 0.102
variable age at onset electroclinical syndrome DOID:0050706 8 0.102
electroclinical syndrome DOID:0050701 32 0.102
cerebral degeneration DOID:1443 16 0.075
neurodegenerative disease DOID:1289 102 0.025
acquired metabolic disease DOID:0060158 58 0.019
progressive myoclonus epilepsy DOID:891 8 0.018
cancer DOID:162 167 0.015
disease of cellular proliferation DOID:14566 174 0.015
muscular disease DOID:0080000 114 0.012
musculoskeletal system disease DOID:17 223 0.012
muscle tissue disease DOID:66 113 0.012
connective tissue disease DOID:65 109 0.011
sensory system disease DOID:0050155 203 0.010
eye and adnexa disease DOID:1492 150 0.010