Homo sapiens

132 known processes

LAMP1

lysosomal-associated membrane protein 1

(Aliases: LGP120,CD107a,LAMPA)

LAMP1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
lipid catabolic process GO:0016042 84 0.921
liposaccharide metabolic process GO:1903509 27 0.840
cellular lipid catabolic process GO:0044242 65 0.833
membrane lipid metabolic process GO:0006643 53 0.741
sphingoid metabolic process GO:0046519 8 0.626
sphingolipid metabolic process GO:0006665 38 0.587
lipid biosynthetic process GO:0008610 177 0.579
regulation of mapk cascade GO:0043408 262 0.577
organic hydroxy compound biosynthetic process GO:1901617 71 0.517
regulation of map kinase activity GO:0043405 108 0.450
interleukin 6 production GO:0032635 37 0.447
signal transduction by phosphorylation GO:0023014 297 0.440
glucosylceramide metabolic process GO:0006678 3 0.438
mapk cascade GO:0000165 288 0.435
regulation of kinase activity GO:0043549 314 0.404
ceramide metabolic process GO:0006672 25 0.400
regulation of interleukin 6 production GO:0032675 37 0.373
organic hydroxy compound metabolic process GO:1901615 147 0.365
regulation of cytokine production GO:0001817 232 0.342
negative regulation of protein serine threonine kinase activity GO:0071901 57 0.333
regulation of protein serine threonine kinase activity GO:0071900 179 0.328
alcohol metabolic process GO:0006066 114 0.324
vacuole organization GO:0007033 44 0.318
organonitrogen compound biosynthetic process GO:1901566 200 0.291
cellular response to tumor necrosis factor GO:0071356 63 0.278
determination of adult lifespan GO:0008340 2 0.273
negative regulation of cytokine production GO:0001818 82 0.272
chemical homeostasis GO:0048878 306 0.268
response to cytokine GO:0034097 232 0.259
post embryonic development GO:0009791 2 0.238
small molecule biosynthetic process GO:0044283 157 0.223
regulation of protein dephosphorylation GO:0035304 18 0.217
ganglioside catabolic process GO:0006689 3 0.209
negative regulation of cellular protein metabolic process GO:0032269 353 0.200
regulation of transferase activity GO:0051338 355 0.196
polyol metabolic process GO:0019751 32 0.191
protein dephosphorylation GO:0006470 81 0.186
glycosphingolipid metabolic process GO:0006687 13 0.172
negative regulation of protein kinase activity GO:0006469 98 0.152
vesicle mediated transport GO:0016192 371 0.151
negative regulation of catalytic activity GO:0043086 335 0.149
cellular amide metabolic process GO:0043603 69 0.148
alcohol biosynthetic process GO:0046165 52 0.146
response to tumor necrosis factor GO:0034612 76 0.133
epithelium development GO:0060429 227 0.132
cytokine production GO:0001816 247 0.128
negative regulation of protein phosphorylation GO:0001933 140 0.126
membrane lipid biosynthetic process GO:0046467 27 0.125
cellular response to cytokine stimulus GO:0071345 181 0.124
negative regulation of multicellular organismal process GO:0051241 317 0.122
membrane lipid catabolic process GO:0046466 10 0.112
diol biosynthetic process GO:0034312 4 0.112
negative regulation of phosphate metabolic process GO:0045936 267 0.109
negative regulation of protein metabolic process GO:0051248 391 0.109
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.108
negative regulation of intracellular signal transduction GO:1902532 183 0.107
locomotory behavior GO:0007626 1 0.107
transmembrane transport GO:0055085 399 0.106
sphingosine biosynthetic process GO:0046512 4 0.105
cell development GO:0048468 328 0.105
negative regulation of map kinase activity GO:0043407 27 0.100
dephosphorylation GO:0016311 209 0.098
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.098
negative regulation of transferase activity GO:0051348 124 0.097
protein maturation GO:0051604 233 0.096
carbohydrate metabolic process GO:0005975 207 0.093
ceramide catabolic process GO:0046514 6 0.089
negative regulation of protein modification process GO:0031400 200 0.089
peripheral nervous system development GO:0007422 2 0.085
regulation of systemic arterial blood pressure by circulatory renin angiotensin GO:0001991 4 0.082
ion homeostasis GO:0050801 230 0.081
circulatory system development GO:0072359 262 0.079
regulation of cellular amino acid metabolic process GO:0006521 6 0.075
sphingolipid biosynthetic process GO:0030148 18 0.075
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.073
multicellular organismal aging GO:0010259 3 0.072
lipid localization GO:0010876 106 0.070
sphingosine metabolic process GO:0006670 6 0.070
mating GO:0007618 1 0.069
glucosylceramide catabolic process GO:0006680 2 0.068
glycolipid catabolic process GO:0019377 8 0.066
female gamete generation GO:0007292 2 0.064
anatomical structure homeostasis GO:0060249 100 0.064
negative regulation of phosphorylation GO:0042326 174 0.063
membrane protein proteolysis GO:0033619 38 0.060
regulation of systemic arterial blood pressure by hormone GO:0001990 12 0.059
neuromuscular process GO:0050905 15 0.058
regulation of dephosphorylation GO:0035303 96 0.058
negative regulation of kinase activity GO:0033673 106 0.057
lipid metabolic process GO:0006629 381 0.056
negative regulation of interleukin 6 production GO:0032715 13 0.055
prostate gland development GO:0030850 3 0.054
cellular ketone metabolic process GO:0042180 80 0.054
cellular amino acid metabolic process GO:0006520 116 0.052
neurogenesis GO:0022008 169 0.051
lymphocyte activation GO:0046649 133 0.051
regulation of peptidase activity GO:0052547 180 0.051
wnt signaling pathway GO:0016055 156 0.050
negative regulation of oxidative stress induced cell death GO:1903202 17 0.049
sphingoid biosynthetic process GO:0046520 5 0.047
diol metabolic process GO:0034311 6 0.046
nervous system development GO:0007399 293 0.045
monovalent inorganic cation homeostasis GO:0055067 37 0.045
maintenance of location GO:0051235 112 0.044
negative regulation of cell death GO:0060548 345 0.044
neuron differentiation GO:0030182 138 0.042
response to thyroid hormone GO:0097066 9 0.042
cellular ion homeostasis GO:0006873 168 0.042
peptide metabolic process GO:0006518 51 0.042
protein localization to organelle GO:0033365 280 0.041
glycosphingolipid catabolic process GO:0046479 6 0.041
cellular lipid metabolic process GO:0044255 303 0.041
carbohydrate catabolic process GO:0016052 36 0.040
cellular chemical homeostasis GO:0055082 180 0.040
protein modification by small protein conjugation GO:0032446 342 0.038
glycosylceramide catabolic process GO:0046477 3 0.038
positive regulation of protein dephosphorylation GO:0035307 16 0.037
oogenesis GO:0048477 2 0.036
protein processing GO:0016485 226 0.036
negative regulation of mapk cascade GO:0043409 56 0.035
negative regulation of programmed cell death GO:0043069 321 0.035
metal ion homeostasis GO:0055065 169 0.034
cation homeostasis GO:0055080 189 0.034
single organism carbohydrate metabolic process GO:0044723 193 0.033
cellular homeostasis GO:0019725 196 0.033
epithelial cell proliferation GO:0050673 128 0.032
vasculature development GO:0001944 181 0.032
growth GO:0040007 202 0.032
regulation of cellular amine metabolic process GO:0033238 11 0.032
neurological system process GO:0050877 163 0.032
cellular calcium ion homeostasis GO:0006874 117 0.031
response to axon injury GO:0048678 1 0.031
positive regulation of phosphorylation GO:0042327 394 0.031
amine metabolic process GO:0009308 44 0.031
blastocyst development GO:0001824 3 0.031
immune response GO:0006955 307 0.030
defense response GO:0006952 315 0.030
apoptotic signaling pathway GO:0097190 268 0.030
monovalent inorganic cation transport GO:0015672 128 0.030
cellular macromolecule catabolic process GO:0044265 380 0.029
proteoglycan metabolic process GO:0006029 29 0.029
inorganic cation transmembrane transport GO:0098662 194 0.028
aminoglycan metabolic process GO:0006022 39 0.028
cell death in response to oxidative stress GO:0036473 29 0.028
cellular protein catabolic process GO:0044257 261 0.028
single organism membrane organization GO:0044802 268 0.028
organophosphate biosynthetic process GO:0090407 163 0.028
protein catabolic process GO:0030163 325 0.028
embryo development GO:0009790 123 0.027
ganglioside metabolic process GO:0001573 7 0.027
negative regulation of cellular response to oxidative stress GO:1900408 18 0.027
secretion GO:0046903 254 0.027
regulation of wnt signaling pathway GO:0030111 123 0.027
inorganic ion transmembrane transport GO:0098660 231 0.027
positive regulation of dephosphorylation GO:0035306 26 0.027
proteasomal protein catabolic process GO:0010498 176 0.027
anatomical structure formation involved in morphogenesis GO:0048646 284 0.026
system process GO:0003008 349 0.026
glycolipid metabolic process GO:0006664 27 0.026
secretion by cell GO:0032940 226 0.026
regulation of protein maturation GO:1903317 150 0.026
epithelial cell differentiation GO:0030855 141 0.025
protein localization to endoplasmic reticulum GO:0070972 19 0.025
regulation of protein processing GO:0070613 150 0.025
cellular component morphogenesis GO:0032989 314 0.025
ceramide biosynthetic process GO:0046513 11 0.024
positive regulation of developmental process GO:0051094 314 0.024
cell activation GO:0001775 213 0.024
cardiovascular system development GO:0072358 262 0.024
exocytosis GO:0006887 71 0.024
cellular amine metabolic process GO:0044106 41 0.024
negative regulation of cell motility GO:2000146 104 0.023
positive regulation of natural killer cell activation GO:0032816 8 0.023
reproductive process GO:0022414 106 0.023
ubiquitin dependent protein catabolic process GO:0006511 206 0.023
negative regulation of cellular amine metabolic process GO:0033239 3 0.023
regulation of vasculature development GO:1901342 97 0.022
regulation of cellular component movement GO:0051270 334 0.022
negative regulation of protein processing GO:0010955 142 0.022
cellular cation homeostasis GO:0030003 163 0.022
cellular metal ion homeostasis GO:0006875 146 0.021
establishment of protein localization to organelle GO:0072594 172 0.021
regulation of blood vessel remodeling GO:0060312 2 0.021
positive regulation of mapk cascade GO:0043410 190 0.020
natural killer cell activation involved in immune response GO:0002323 2 0.020
regulation of anatomical structure morphogenesis GO:0022603 286 0.020
modification dependent protein catabolic process GO:0019941 209 0.020
hair cell differentiation GO:0035315 2 0.020
regulation of growth GO:0040008 165 0.020
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.019
glycosylceramide metabolic process GO:0006677 6 0.019
generation of neurons GO:0048699 152 0.019
modification dependent macromolecule catabolic process GO:0043632 212 0.019
response to oxidative stress GO:0006979 121 0.019
regulation of cellular ketone metabolic process GO:0010565 50 0.019
adult locomotory behavior GO:0008344 1 0.019
negative regulation of fibroblast growth factor receptor signaling pathway GO:0040037 2 0.019
cellular divalent inorganic cation homeostasis GO:0072503 128 0.019
neuronal action potential GO:0019228 9 0.019
positive regulation of cellular component organization GO:0051130 376 0.019
positive regulation of cellular amine metabolic process GO:0033240 7 0.019
regulation of cellular response to stress GO:0080135 244 0.018
negative regulation of apoptotic process GO:0043066 316 0.018
regulation of blood pressure GO:0008217 30 0.018
innate immune response GO:0045087 178 0.018
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.018
positive regulation of transport GO:0051050 336 0.018
regulation of proteolysis GO:0030162 293 0.018
cell projection organization GO:0030030 252 0.018
cytoplasmic transport GO:0016482 379 0.018
regulation of lipid metabolic process GO:0019216 96 0.018
establishment of planar polarity GO:0001736 3 0.018
response to oxygen containing compound GO:1901700 369 0.017
i kappab kinase nf kappab signaling GO:0007249 166 0.017
neuromuscular junction development GO:0007528 3 0.017
t cell activation GO:0042110 99 0.017
sulfur compound metabolic process GO:0006790 101 0.017
calcium ion homeostasis GO:0055074 122 0.017
endocytosis GO:0006897 159 0.017
hindbrain development GO:0030902 3 0.017
angiogenesis GO:0001525 147 0.017
regulation of angiotensin levels in blood GO:0002002 3 0.017
skeletal system development GO:0001501 79 0.016
regulation of intracellular transport GO:0032386 195 0.016
response to nitrogen compound GO:1901698 184 0.016
neuron development GO:0048666 113 0.016
cell part morphogenesis GO:0032990 137 0.016
negative regulation of locomotion GO:0040013 118 0.016
regulation of cell differentiation GO:0045595 393 0.016
multicellular organismal homeostasis GO:0048871 67 0.016
lymphocyte proliferation GO:0046651 70 0.016
glycoprotein metabolic process GO:0009100 110 0.016
phospholipid biosynthetic process GO:0008654 44 0.016
lipid storage GO:0019915 28 0.016
blood vessel morphogenesis GO:0048514 162 0.016
carbohydrate derivative biosynthetic process GO:1901137 207 0.016
negative regulation of cellular component movement GO:0051271 106 0.016
membrane protein ectodomain proteolysis GO:0006509 33 0.016
oocyte development GO:0048599 1 0.016
single organism reproductive process GO:0044702 98 0.016
chemical homeostasis within a tissue GO:0048875 3 0.015
cell morphogenesis GO:0000902 296 0.015
leukocyte activation GO:0045321 164 0.015
establishment of organelle localization GO:0051656 59 0.015
divalent inorganic cation homeostasis GO:0072507 136 0.015
negative regulation of proteolysis GO:0045861 132 0.015
central nervous system development GO:0007417 123 0.015
antigen processing and presentation GO:0019882 33 0.015
regulation of protein kinase activity GO:0045859 289 0.015
tissue homeostasis GO:0001894 63 0.015
t cell proliferation GO:0042098 45 0.015
membrane organization GO:0061024 292 0.015
hormone metabolic process GO:0042445 61 0.015
macromolecule glycosylation GO:0043413 63 0.015
intrinsic apoptotic signaling pathway GO:0097193 127 0.015
mononuclear cell proliferation GO:0032943 71 0.015
negative regulation of cell proliferation GO:0008285 228 0.015
ribonucleotide catabolic process GO:0009261 405 0.015
negative regulation of cellular component organization GO:0051129 235 0.015
polyol biosynthetic process GO:0046173 17 0.014
intracellular protein transport GO:0006886 270 0.014
immune effector process GO:0002252 159 0.014
glycoprotein biosynthetic process GO:0009101 91 0.014
response to abiotic stimulus GO:0009628 336 0.014
negative regulation of cell migration GO:0030336 102 0.014
hemopoiesis GO:0030097 180 0.014
tissue regeneration GO:0042246 3 0.014
pigmentation GO:0043473 22 0.014
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.014
ribonucleoside triphosphate metabolic process GO:0009199 412 0.014
posttranscriptional regulation of gene expression GO:0010608 213 0.014
Mouse
cation transmembrane transport GO:0098655 238 0.014
purine containing compound catabolic process GO:0072523 411 0.014
oocyte differentiation GO:0009994 2 0.014
cation transport GO:0006812 331 0.014
regulation of membrane potential GO:0042391 95 0.013
nephric duct development GO:0072176 4 0.013
negative regulation of metalloenzyme activity GO:0048553 1 0.013
kidney development GO:0001822 53 0.013
transmission of nerve impulse GO:0019226 11 0.013
long term memory GO:0007616 2 0.013
ph reduction GO:0045851 11 0.013
regulation of secretion GO:0051046 194 0.013
skin development GO:0043588 76 0.013
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 43 0.013
metencephalon development GO:0022037 2 0.013
microtubule based process GO:0007017 210 0.013
atp metabolic process GO:0046034 176 0.013
syncytium formation by plasma membrane fusion GO:0000768 2 0.013
myeloid cell differentiation GO:0030099 117 0.013
protein glycosylation GO:0006486 62 0.013
negative regulation of peptidase activity GO:0010466 91 0.013
regulation of rubidium ion transport GO:2000680 3 0.013
segmentation GO:0035282 4 0.013
gland development GO:0048732 48 0.013
purine ribonucleotide catabolic process GO:0009154 404 0.013
cellular response to oxygen containing compound GO:1901701 276 0.013
regeneration GO:0031099 4 0.013
memory GO:0007613 3 0.012
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.012
positive regulation of organelle organization GO:0010638 195 0.012
negative regulation of hydrolase activity GO:0051346 182 0.012
nucleoside monophosphate metabolic process GO:0009123 191 0.012
regulation of apoptotic signaling pathway GO:2001233 175 0.012
protein ubiquitination GO:0016567 314 0.012
enzyme linked receptor protein signaling pathway GO:0007167 303 0.012
negative regulation of extracellular matrix disassembly GO:0010716 3 0.012
ion transmembrane transport GO:0034220 338 0.012
action potential GO:0001508 34 0.012
cellular response to hydrogen peroxide GO:0070301 37 0.012
rho protein signal transduction GO:0007266 26 0.012
axis elongation GO:0003401 4 0.012
regulation of lymphocyte activation GO:0051249 103 0.012
cellular response to external stimulus GO:0071496 111 0.012
regulation of oxidative stress induced cell death GO:1903201 24 0.012
nucleotide catabolic process GO:0009166 408 0.012
cilium assembly GO:0042384 63 0.012
autophagy GO:0006914 88 0.012
embryo development ending in birth or egg hatching GO:0009792 34 0.012
notch receptor processing GO:0007220 2 0.012
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.012
receptor metabolic process GO:0043112 81 0.012
regulation of cell morphogenesis GO:0022604 153 0.012
rubidium ion transport GO:0035826 4 0.012
female pregnancy GO:0007565 17 0.012
glycosyl compound catabolic process GO:1901658 413 0.012
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090100 41 0.011
divalent inorganic cation transport GO:0072511 158 0.011
positive regulation of cell development GO:0010720 92 0.011
phospholipid metabolic process GO:0006644 99 0.011
cerebellum development GO:0021549 2 0.011
regulation of intrinsic apoptotic signaling pathway GO:2001242 72 0.011
positive regulation of secretion GO:0051047 116 0.011
vacuolar transport GO:0007034 34 0.011
hexose catabolic process GO:0019320 7 0.011
blastoderm segmentation GO:0007350 2 0.011
peptidyl tyrosine modification GO:0018212 170 0.011
positive regulation of secretion by cell GO:1903532 108 0.011
regulation of vesicle mediated transport GO:0060627 130 0.011
regulation of cell development GO:0060284 161 0.011
response to radiation GO:0009314 151 0.011
regulation of cell motility GO:2000145 299 0.011
cellular pigmentation GO:0033059 17 0.011
cellular macromolecular complex assembly GO:0034622 324 0.011
spermatid differentiation GO:0048515 4 0.011
amyloid precursor protein metabolic process GO:0042982 17 0.011
cellular protein complex assembly GO:0043623 188 0.011
purine nucleoside triphosphate metabolic process GO:0009144 412 0.011
regulation of osteoblast differentiation GO:0045667 38 0.011
regulation of cell cycle GO:0051726 393 0.011
cell projection morphogenesis GO:0048858 129 0.011
head development GO:0060322 108 0.011
positive regulation of cellular catabolic process GO:0031331 284 0.011
negative regulation of glycoprotein metabolic process GO:1903019 8 0.011
negative regulation of phosphorus metabolic process GO:0010563 267 0.011
response to starvation GO:0042594 59 0.011
oligosaccharide metabolic process GO:0009311 13 0.011
positive regulation of programmed cell death GO:0043068 249 0.011
positive regulation of cell proliferation GO:0008284 301 0.011
cellular response to endogenous stimulus GO:0071495 336 0.011
golgi to vacuole transport GO:0006896 3 0.010
glycosylation GO:0070085 71 0.010
cellular response to reactive oxygen species GO:0034614 50 0.010
positive regulation of wnt signaling pathway GO:0030177 54 0.010
leukocyte proliferation GO:0070661 74 0.010
cell adhesion GO:0007155 325 0.010
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.010
sensory perception of pain GO:0019233 4 0.010
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.010
myeloid leukocyte differentiation GO:0002573 60 0.010
purine ribonucleoside metabolic process GO:0046128 437 0.010
organophosphate catabolic process GO:0046434 430 0.010

LAMP1 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 1.000
Human
lysosomal storage disease DOID:3211 47 1.000
Human
inherited metabolic disorder DOID:655 242 1.000
Human
lipid storage disease DOID:9455 28 1.000
central nervous system disease DOID:331 186 0.963
nervous system disease DOID:863 431 0.963
sphingolipidosis DOID:1927 14 0.754
disease of mental health DOID:150 70 0.685
cognitive disorder DOID:1561 29 0.685
neurodegenerative disease DOID:1289 102 0.673
synucleinopathy DOID:0050890 22 0.632
parkinson s disease DOID:14330 18 0.621
dementia DOID:1307 19 0.515
cerebral degeneration DOID:1443 16 0.236
brain disease DOID:936 73 0.236
neuronal ceroid lipofuscinosis DOID:14503 11 0.176
mucopolysaccharidosis DOID:12798 11 0.142
skin disease DOID:37 33 0.056
integumentary system disease DOID:16 43 0.056
immune system disease DOID:2914 155 0.021
disease of cellular proliferation DOID:14566 174 0.017
sensory system disease DOID:0050155 203 0.016
eye and adnexa disease DOID:1492 150 0.016
eye disease DOID:5614 149 0.016
cancer DOID:162 167 0.013
epilepsy syndrome DOID:1826 41 0.013
variable age at onset electroclinical syndrome DOID:0050706 8 0.013
electroclinical syndrome DOID:0050701 32 0.013
progressive myoclonus epilepsy DOID:891 8 0.013
leukodystrophy DOID:10579 8 0.011