Homo sapiens

133 known processes

DENND4B

DENN/MADD domain containing 4B

(Aliases: FLJ26202,KIAA0476,DKFZp762N174)

DENND4B biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
purine nucleoside triphosphate metabolic process GO:0009144 412 0.082
cellular amine metabolic process GO:0044106 41 0.080
cellular amino acid metabolic process GO:0006520 116 0.076
amine metabolic process GO:0009308 44 0.068
regulation of cellular amine metabolic process GO:0033238 11 0.066
histone modification GO:0016570 251 0.063
cellular ketone metabolic process GO:0042180 80 0.062
post embryonic development GO:0009791 2 0.062
membrane organization GO:0061024 292 0.057
covalent chromatin modification GO:0016569 254 0.055
ras protein signal transduction GO:0007265 73 0.055
actin filament based process GO:0030029 224 0.055
regulation of cell differentiation GO:0045595 393 0.054
regulation of cellular amino acid metabolic process GO:0006521 6 0.053
lipid metabolic process GO:0006629 381 0.051
ribonucleoside triphosphate metabolic process GO:0009199 412 0.050
rab protein signal transduction GO:0032482 4 0.050
purine nucleoside triphosphate catabolic process GO:0009146 392 0.049
glycosyl compound catabolic process GO:1901658 413 0.049
regulation of cellular ketone metabolic process GO:0010565 50 0.048
chromatin organization GO:0006325 351 0.047
purine nucleotide catabolic process GO:0006195 405 0.047
negative regulation of catalytic activity GO:0043086 335 0.045
glycerolipid metabolic process GO:0046486 107 0.043
nucleoside triphosphate metabolic process GO:0009141 422 0.042
chromatin modification GO:0016568 298 0.042
cellular macromolecular complex assembly GO:0034622 324 0.041
negative regulation of phosphate metabolic process GO:0045936 267 0.041
rna processing GO:0006396 255 0.039
positive regulation of catabolic process GO:0009896 310 0.039
cell projection organization GO:0030030 252 0.039
positive regulation of gtpase activity GO:0043547 166 0.039
purine nucleoside catabolic process GO:0006152 398 0.038
gtp metabolic process GO:0046039 239 0.038
actin cytoskeleton organization GO:0030036 207 0.038
regulation of ras gtpase activity GO:0032318 128 0.038
small gtpase mediated signal transduction GO:0007264 78 0.037
cellular component morphogenesis GO:0032989 314 0.037
rho protein signal transduction GO:0007266 26 0.037
negative regulation of phosphorus metabolic process GO:0010563 267 0.036
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.036
compound eye development GO:0048749 1 0.036
immune response GO:0006955 307 0.036
cell development GO:0048468 328 0.035
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.035
cellular lipid metabolic process GO:0044255 303 0.034
mrna metabolic process GO:0016071 175 0.033
g protein coupled receptor signaling pathway GO:0007186 207 0.032
negative regulation of cellular protein metabolic process GO:0032269 353 0.032
defense response to other organism GO:0098542 129 0.032
ribonucleoside triphosphate catabolic process GO:0009203 391 0.032
protein acetylation GO:0006473 116 0.032
regulation of protein serine threonine kinase activity GO:0071900 179 0.031
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.031
nucleoside triphosphate catabolic process GO:0009143 394 0.031
single organism membrane organization GO:0044802 268 0.031
purine ribonucleotide catabolic process GO:0009154 404 0.031
negative regulation of cellular amine metabolic process GO:0033239 3 0.031
regulation of ras protein signal transduction GO:0046578 155 0.030
positive regulation of rab gtpase activity GO:0032851 39 0.030
response to biotic stimulus GO:0009607 276 0.030
positive regulation of cellular catabolic process GO:0031331 284 0.030
actin filament organization GO:0007015 128 0.030
segmentation GO:0035282 4 0.030
protein modification by small protein conjugation GO:0032446 342 0.030
regulation of immune response GO:0050776 201 0.030
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.029
purine containing compound catabolic process GO:0072523 411 0.029
morphogenesis of embryonic epithelium GO:0016331 4 0.028
response to oxygen containing compound GO:1901700 369 0.028
regulation of kinase activity GO:0043549 314 0.028
positive regulation of ras gtpase activity GO:0032320 117 0.028
regulation of protein kinase activity GO:0045859 289 0.028
secretion by cell GO:0032940 226 0.028
regulation of purine nucleotide metabolic process GO:1900542 264 0.028
locomotory behavior GO:0007626 1 0.027
organophosphate biosynthetic process GO:0090407 163 0.027
defense response GO:0006952 315 0.027
blastoderm segmentation GO:0007350 2 0.027
female gamete generation GO:0007292 2 0.027
cytoplasmic transport GO:0016482 379 0.026
response to organonitrogen compound GO:0010243 156 0.026
purine ribonucleoside metabolic process GO:0046128 437 0.026
immune effector process GO:0002252 159 0.026
cell morphogenesis GO:0000902 296 0.026
system process GO:0003008 349 0.025
innate immune response GO:0045087 178 0.025
oogenesis GO:0048477 2 0.025
carbohydrate metabolic process GO:0005975 207 0.025
histone acetylation GO:0016573 93 0.025
memory GO:0007613 3 0.024
ribonucleoside catabolic process GO:0042454 406 0.024
multicellular organismal aging GO:0010259 3 0.024
negative regulation of protein modification process GO:0031400 200 0.024
signal transduction by phosphorylation GO:0023014 297 0.024
anion transport GO:0006820 161 0.024
negative regulation of multicellular organismal process GO:0051241 317 0.023
negative regulation of protein metabolic process GO:0051248 391 0.023
peptidyl lysine acetylation GO:0018394 101 0.023
response to other organism GO:0051707 261 0.023
regulation of nucleotide metabolic process GO:0006140 269 0.023
nucleoside phosphate catabolic process GO:1901292 412 0.023
regulation of nucleoside metabolic process GO:0009118 209 0.023
determination of adult lifespan GO:0008340 2 0.022
dephosphorylation GO:0016311 209 0.022
regulation of transferase activity GO:0051338 355 0.022
peripheral nervous system development GO:0007422 2 0.022
regulation of rab protein signal transduction GO:0032483 39 0.021
cellular macromolecule catabolic process GO:0044265 380 0.021
response to external biotic stimulus GO:0043207 261 0.021
negative regulation of developmental process GO:0051093 247 0.020
neurogenesis GO:0022008 169 0.020
negative regulation of protein phosphorylation GO:0001933 140 0.020
negative regulation of phosphorylation GO:0042326 174 0.020
negative regulation of cell death GO:0060548 345 0.020
protein acylation GO:0043543 138 0.020
regulation of small gtpase mediated signal transduction GO:0051056 156 0.020
positive regulation of hydrolase activity GO:0051345 331 0.020
single organism carbohydrate metabolic process GO:0044723 193 0.020
glycerophospholipid metabolic process GO:0006650 84 0.020
regulation of anatomical structure morphogenesis GO:0022603 286 0.019
positive regulation of cellular component organization GO:0051130 376 0.019
nervous system development GO:0007399 293 0.019
peptidyl lysine modification GO:0018205 144 0.019
protein ubiquitination GO:0016567 314 0.018
regulation of proteolysis GO:0030162 293 0.018
negative regulation of programmed cell death GO:0043069 321 0.018
rhythmic behavior GO:0007622 2 0.018
nucleotide catabolic process GO:0009166 408 0.018
ribonucleoside monophosphate metabolic process GO:0009161 187 0.018
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.018
actin filament based movement GO:0030048 17 0.018
actin mediated cell contraction GO:0070252 12 0.018
regulation of protein transport GO:0051223 213 0.018
regulation of dna metabolic process GO:0051052 153 0.018
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.018
transmembrane transport GO:0055085 399 0.018
neuromuscular junction development GO:0007528 3 0.018
organic hydroxy compound metabolic process GO:1901615 147 0.018
atp metabolic process GO:0046034 176 0.018
negative regulation of cellular component organization GO:0051129 235 0.018
positive regulation of nucleotide catabolic process GO:0030813 185 0.017
alcohol metabolic process GO:0006066 114 0.017
primary neural tube formation GO:0014020 3 0.017
regeneration GO:0031099 4 0.017
nucleoside catabolic process GO:0009164 408 0.017
regulation of endopeptidase activity GO:0052548 170 0.017
nitrogen compound transport GO:0071705 191 0.017
regulation of mapk cascade GO:0043408 262 0.017
monosaccharide metabolic process GO:0005996 74 0.017
regulation of establishment of protein localization GO:0070201 242 0.017
positive regulation of cell differentiation GO:0045597 211 0.017
intracellular protein transport GO:0006886 270 0.017
single organism cellular localization GO:1902580 332 0.017
long term memory GO:0007616 2 0.017
circadian behavior GO:0048512 2 0.016
positive regulation of organelle organization GO:0010638 195 0.016
response to nitrogen compound GO:1901698 184 0.016
proteasomal protein catabolic process GO:0010498 176 0.016
nucleic acid phosphodiester bond hydrolysis GO:0090305 102 0.016
toxin transport GO:1901998 4 0.016
purine nucleoside monophosphate metabolic process GO:0009126 186 0.016
spermatid differentiation GO:0048515 4 0.016
positive regulation of transferase activity GO:0051347 227 0.016
negative regulation of transport GO:0051051 176 0.016
endomembrane system organization GO:0010256 196 0.016
apoptotic signaling pathway GO:0097190 268 0.016
cell part morphogenesis GO:0032990 137 0.016
embryonic epithelial tube formation GO:0001838 4 0.016
cell division GO:0051301 168 0.016
positive regulation of cellular amine metabolic process GO:0033240 7 0.016
organophosphate catabolic process GO:0046434 430 0.016
regulation of cell cycle process GO:0010564 266 0.016
cellular protein complex assembly GO:0043623 188 0.015
morphogenesis of a polarized epithelium GO:0001738 3 0.015
negative regulation of hydrolase activity GO:0051346 182 0.015
positive regulation of phosphorylation GO:0042327 394 0.015
response to abiotic stimulus GO:0009628 336 0.015
cellular response to dna damage stimulus GO:0006974 379 0.015
regulation of neural precursor cell proliferation GO:2000177 4 0.015
peptidyl tyrosine phosphorylation GO:0018108 170 0.015
negative regulation of axonogenesis GO:0050771 4 0.015
hexose metabolic process GO:0019318 55 0.015
protein localization to organelle GO:0033365 280 0.015
gamma aminobutyric acid signaling pathway GO:0007214 3 0.015
regulation of innate immune response GO:0045088 97 0.015
regulation of protein localization GO:0032880 296 0.015
mitotic cell cycle GO:0000278 326 0.015
protein localization to membrane GO:0072657 160 0.015
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.015
positive regulation of nucleoside metabolic process GO:0045979 186 0.015
maintenance of location GO:0051235 112 0.014
cell morphogenesis involved in differentiation GO:0000904 144 0.014
regulation of immune effector process GO:0002697 91 0.014
regulation of multi organism process GO:0043900 157 0.014
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.014
response to fungus GO:0009620 4 0.014
rna splicing GO:0008380 131 0.014
regulation of growth GO:0040008 165 0.014
purine ribonucleoside catabolic process GO:0046130 398 0.014
neural tube formation GO:0001841 3 0.014
protein deubiquitination GO:0016579 79 0.014
negative regulation of cell differentiation GO:0045596 171 0.014
catecholamine secretion GO:0050432 1 0.014
regulation of cell cycle GO:0051726 393 0.014
negative regulation of cell proliferation GO:0008285 228 0.014
phospholipid metabolic process GO:0006644 99 0.014
negative regulation of transferase activity GO:0051348 124 0.014
cellular component disassembly GO:0022411 92 0.014
regulation of defense response GO:0031347 154 0.014
negative regulation of intracellular signal transduction GO:1902532 183 0.014
cellular protein catabolic process GO:0044257 261 0.014
regulation of gtp catabolic process GO:0033124 180 0.014
neural tube closure GO:0001843 3 0.014
mrna processing GO:0006397 133 0.014
protein catabolic process GO:0030163 325 0.014
regulation of mitotic cell cycle phase transition GO:1901990 118 0.014
regulation of secretion by cell GO:1903530 177 0.014
cell cycle phase transition GO:0044770 173 0.014
immune system development GO:0002520 195 0.013
positive regulation of gtp catabolic process GO:0033126 166 0.013
regulation of secretion GO:0051046 194 0.013
positive regulation of cellular component biogenesis GO:0044089 158 0.013
nucleoside monophosphate metabolic process GO:0009123 191 0.013
positive regulation of protein phosphorylation GO:0001934 313 0.013
spermatid development GO:0007286 4 0.013
circulatory system development GO:0072359 262 0.013
mitotic cell cycle process GO:1903047 286 0.013
enzyme linked receptor protein signaling pathway GO:0007167 303 0.013
oocyte development GO:0048599 1 0.013
positive regulation of immune response GO:0050778 159 0.013
protein autophosphorylation GO:0046777 123 0.013
protein oligomerization GO:0051259 173 0.013
defense response to fungus GO:0050832 4 0.013
adult locomotory behavior GO:0008344 1 0.012
regulation of nucleotide catabolic process GO:0030811 205 0.012
oocyte differentiation GO:0009994 2 0.012
posttranscriptional regulation of gene expression GO:0010608 213 0.012
establishment of protein localization to membrane GO:0090150 121 0.012
regulation of cellular component movement GO:0051270 334 0.012
neuron differentiation GO:0030182 138 0.012
regulation of gtpase activity GO:0043087 180 0.012
endochondral bone morphogenesis GO:0060350 3 0.012
golgi vesicle transport GO:0048193 80 0.012
somitogenesis GO:0001756 2 0.012
response to virus GO:0009615 126 0.012
mapk cascade GO:0000165 288 0.012
guanosine containing compound metabolic process GO:1901068 244 0.012
regulation of rna splicing GO:0043484 62 0.012
replacement ossification GO:0036075 1 0.012
regulation of peptidase activity GO:0052547 180 0.012
neuron projection development GO:0031175 106 0.012
regulation of cell migration GO:0030334 289 0.012
internal peptidyl lysine acetylation GO:0018393 97 0.012
positive regulation of immune system process GO:0002684 283 0.012
organonitrogen compound biosynthetic process GO:1901566 200 0.012
neuron development GO:0048666 113 0.012
sex determination GO:0007530 3 0.012
cellular homeostasis GO:0019725 196 0.012
establishment of tissue polarity GO:0007164 3 0.012
ion transmembrane transport GO:0034220 338 0.012
hematopoietic or lymphoid organ development GO:0048534 186 0.012
negative regulation of kinase activity GO:0033673 106 0.011
vesicle organization GO:0016050 62 0.011
cell projection morphogenesis GO:0048858 129 0.011
regulation of map kinase activity GO:0043405 108 0.011
regulation of cytoskeleton organization GO:0051493 177 0.011
positive regulation of nucleotide metabolic process GO:0045981 230 0.011
regulation of cell development GO:0060284 161 0.011
establishment of planar polarity GO:0001736 3 0.011
regulation of chromosome organization GO:0033044 103 0.011
inner ear morphogenesis GO:0042472 4 0.011
nerve development GO:0021675 4 0.011
cellular response to oxygen containing compound GO:1901701 276 0.011
secretion GO:0046903 254 0.011
protein processing GO:0016485 226 0.011
regulation of purine nucleotide catabolic process GO:0033121 205 0.011
positive regulation of cytoskeleton organization GO:0051495 83 0.011
regulation of response to external stimulus GO:0032101 222 0.011
regulation of cell projection organization GO:0031344 107 0.011
positive regulation of kinase activity GO:0033674 204 0.011
organ formation GO:0048645 3 0.011
generation of neurons GO:0048699 152 0.011
lipid biosynthetic process GO:0008610 177 0.011
autophagy GO:0006914 88 0.011
anatomical structure formation involved in morphogenesis GO:0048646 284 0.011
regulation of synaptic plasticity GO:0048167 3 0.011
endosomal transport GO:0016197 129 0.011
Human
small molecule biosynthetic process GO:0044283 157 0.011
modification dependent macromolecule catabolic process GO:0043632 212 0.011
cellular response to endogenous stimulus GO:0071495 336 0.011
convergent extension GO:0060026 1 0.011
inorganic ion transmembrane transport GO:0098660 231 0.011
purine containing compound biosynthetic process GO:0072522 88 0.011
cellular response to organonitrogen compound GO:0071417 124 0.011
multi organism cellular process GO:0044764 156 0.011
chemical homeostasis GO:0048878 306 0.011
oxidation reduction process GO:0055114 396 0.010
positive regulation of proteolysis GO:0045862 142 0.010
protein maturation GO:0051604 233 0.010
regulation of cell cycle phase transition GO:1901987 126 0.010
mitotic nuclear division GO:0007067 119 0.010
hindbrain development GO:0030902 3 0.010
mitotic cell cycle phase transition GO:0044772 162 0.010
cardiovascular system development GO:0072358 262 0.010
head development GO:0060322 108 0.010
defense response to virus GO:0051607 71 0.010
guanosine containing compound catabolic process GO:1901069 239 0.010
cell projection assembly GO:0030031 126 0.010
protein modification by small protein removal GO:0070646 92 0.010
ribonucleotide catabolic process GO:0009261 405 0.010
regulation of protein secretion GO:0050708 86 0.010

DENND4B disease predictions

Disease DO term ID Size Probability Func Analog Org
central nervous system disease DOID:331 186 0.037
nervous system disease DOID:863 431 0.037
joubert syndrome DOID:0050777 18 0.017
musculoskeletal system disease DOID:17 223 0.016
sensory system disease DOID:0050155 203 0.014
eye and adnexa disease DOID:1492 150 0.013
myopathy DOID:423 104 0.011
muscular disease DOID:0080000 114 0.011
muscle tissue disease DOID:66 113 0.011
disease of metabolism DOID:0014667 295 0.011
inherited metabolic disorder DOID:655 242 0.011
cancer DOID:162 167 0.010
disease of cellular proliferation DOID:14566 174 0.010
organ system cancer DOID:0050686 164 0.010
neurodegenerative disease DOID:1289 102 0.010