Homo sapiens

0 known processes

PSME1

proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)

(Aliases: MGC8628,IFI5111,PA28alpha,PA28A,REGalpha)

PSME1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
proteasomal ubiquitin independent protein catabolic process GO:0010499 3 0.938
antigen processing and presentation GO:0019882 33 0.800
Mouse
ubiquitin dependent protein catabolic process GO:0006511 206 0.712
regulation of proteasomal protein catabolic process GO:0061136 87 0.697
Human
modification dependent protein catabolic process GO:0019941 209 0.631
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.619
Human
protein catabolic process GO:0030163 325 0.596
Human
cellular protein catabolic process GO:0044257 261 0.589
Human
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 91 0.588
Human
spindle elongation GO:0051231 4 0.557
isg15 protein conjugation GO:0032020 5 0.454
regulation of endopeptidase activity GO:0052548 170 0.429
Human Mouse
negative regulation of apoptotic signaling pathway GO:2001234 97 0.409
Human
cellular macromolecule catabolic process GO:0044265 380 0.406
Human
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 52 0.373
Human
nucleotide catabolic process GO:0009166 408 0.363
cellular response to cytokine stimulus GO:0071345 181 0.342
regulation of protein catabolic process GO:0042176 155 0.306
Human
positive regulation of peptidase activity GO:0010952 88 0.298
Human Mouse
proteasomal protein catabolic process GO:0010498 176 0.291
Human
determination of adult lifespan GO:0008340 2 0.267
negative regulation of programmed cell death GO:0043069 321 0.264
Human
regulation of peptidase activity GO:0052547 180 0.228
Human Mouse
positive regulation of osteoblast differentiation GO:0045669 23 0.227
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.207
viral process GO:0016032 146 0.188
regulation of apoptotic signaling pathway GO:2001233 175 0.188
Human
negative regulation of cell death GO:0060548 345 0.176
Human
nervous system development GO:0007399 293 0.174
nucleoside triphosphate catabolic process GO:0009143 394 0.167
positive regulation of endopeptidase activity GO:0010950 84 0.162
Human Mouse
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.160
positive regulation of hydrolase activity GO:0051345 331 0.141
Human Mouse
ossification GO:0001503 121 0.139
post embryonic development GO:0009791 2 0.128
viral entry into host cell GO:0046718 24 0.114
negative regulation of cell migration GO:0030336 102 0.107
ribonucleoside triphosphate metabolic process GO:0009199 412 0.094
modification dependent macromolecule catabolic process GO:0043632 212 0.090
multicellular organismal aging GO:0010259 3 0.090
regulation of cellular component movement GO:0051270 334 0.088
negative regulation of cell motility GO:2000146 104 0.080
movement in environment of other organism involved in symbiotic interaction GO:0052192 25 0.075
extrinsic apoptotic signaling pathway GO:0097191 119 0.074
Human
regulation of proteolysis GO:0030162 293 0.071
Human Mouse
mitotic cell cycle process GO:1903047 286 0.068
intracellular protein transport GO:0006886 270 0.060
cellular component morphogenesis GO:0032989 314 0.059
purine nucleoside catabolic process GO:0006152 398 0.058
negative regulation of leukocyte mediated immunity GO:0002704 14 0.058
regulation of antigen processing and presentation of peptide antigen GO:0002583 4 0.057
nucleoside phosphate biosynthetic process GO:1901293 109 0.056
entry into cell of other organism involved in symbiotic interaction GO:0051806 25 0.055
purine nucleoside monophosphate metabolic process GO:0009126 186 0.053
negative regulation of protein metabolic process GO:0051248 391 0.053
negative regulation of type i interferon mediated signaling pathway GO:0060339 4 0.051
negative regulation of cellular protein metabolic process GO:0032269 353 0.050
chemical homeostasis GO:0048878 306 0.050
regulation of locomotion GO:0040012 329 0.049
purine ribonucleotide catabolic process GO:0009154 404 0.049
entry into host GO:0044409 25 0.047
cation transport GO:0006812 331 0.047
negative regulation of cellular component movement GO:0051271 106 0.047
ribonucleoside triphosphate catabolic process GO:0009203 391 0.046
t cell proliferation GO:0042098 45 0.045
microtubule organizing center organization GO:0031023 62 0.045
nucleoside phosphate catabolic process GO:1901292 412 0.044
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 109 0.043
purine ribonucleoside metabolic process GO:0046128 437 0.043
oogenesis GO:0048477 2 0.041
negative regulation of locomotion GO:0040013 118 0.041
posttranscriptional regulation of gene expression GO:0010608 213 0.041
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.040
regulation of purine nucleotide catabolic process GO:0033121 205 0.040
anatomical structure formation involved in morphogenesis GO:0048646 284 0.040
viral life cycle GO:0019058 132 0.037
negative regulation of catalytic activity GO:0043086 335 0.037
positive regulation of cell differentiation GO:0045597 211 0.035
regulation of cell motility GO:2000145 299 0.035
osteoblast differentiation GO:0001649 92 0.034
cellular macromolecular complex assembly GO:0034622 324 0.033
blastocyst development GO:0001824 3 0.033
response to other organism GO:0051707 261 0.032
cytokine mediated signaling pathway GO:0019221 109 0.032
positive regulation of developmental process GO:0051094 314 0.031
purine nucleotide catabolic process GO:0006195 405 0.030
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.030
multi organism localization GO:1902579 14 0.030
regulation of transferase activity GO:0051338 355 0.029
purine containing compound catabolic process GO:0072523 411 0.029
purine nucleoside triphosphate metabolic process GO:0009144 412 0.029
negative regulation of viral entry into host cell GO:0046597 12 0.029
negative regulation of phosphorylation GO:0042326 174 0.027
negative regulation of gene silencing by rna GO:0060967 3 0.026
response to muramyl dipeptide GO:0032495 4 0.026
negative regulation of cell proliferation GO:0008285 228 0.026
purine ribonucleoside catabolic process GO:0046130 398 0.026
positive regulation of cellular catabolic process GO:0031331 284 0.025
metal ion transport GO:0030001 272 0.025
cellular response to endogenous stimulus GO:0071495 336 0.025
ribonucleoside catabolic process GO:0042454 406 0.024
cell morphogenesis GO:0000902 296 0.024
regulation of cell differentiation GO:0045595 393 0.024
ribonucleoside monophosphate catabolic process GO:0009158 158 0.024
negative regulation of protein modification process GO:0031400 200 0.023
purine nucleoside triphosphate catabolic process GO:0009146 392 0.023
rna modification GO:0009451 27 0.023
cellular lipid metabolic process GO:0044255 303 0.022
positive regulation of nucleoside metabolic process GO:0045979 186 0.022
multi organism cellular process GO:0044764 156 0.022
rna processing GO:0006396 255 0.021
molting cycle GO:0042303 28 0.021
cellular response to hormone stimulus GO:0032870 125 0.021
entry into host cell GO:0030260 25 0.021
adenosine to inosine editing GO:0006382 3 0.021
activation of cysteine type endopeptidase activity GO:0097202 57 0.020
cell activation GO:0001775 213 0.020
regulation of protein stability GO:0031647 87 0.020
regulation of membrane potential GO:0042391 95 0.020
membrane organization GO:0061024 292 0.019
negative regulation of phosphate metabolic process GO:0045936 267 0.019
t cell activation GO:0042110 99 0.019
mitotic spindle elongation GO:0000022 4 0.019
negative regulation of developmental process GO:0051093 247 0.018
negative regulation of apoptotic process GO:0043066 316 0.018
Human
regulation of viral transcription GO:0046782 34 0.018
regulation of cell migration GO:0030334 289 0.018
embryo development GO:0009790 123 0.017
negative regulation of cell differentiation GO:0045596 171 0.017
glycerophospholipid metabolic process GO:0006650 84 0.017
antigen processing and presentation of peptide antigen GO:0048002 18 0.017
response to hormone GO:0009725 175 0.016
positive regulation of apoptotic process GO:0043065 246 0.016
proteasome assembly GO:0043248 7 0.016
mrna metabolic process GO:0016071 175 0.016
cellular amino acid metabolic process GO:0006520 116 0.016
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.015
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.015
regulation of interferon gamma production GO:0032649 36 0.015
negative regulation of kinase activity GO:0033673 106 0.015
positive regulation of response to external stimulus GO:0032103 88 0.015
regulation of anatomical structure morphogenesis GO:0022603 286 0.014
organophosphate catabolic process GO:0046434 430 0.014
oxidation reduction process GO:0055114 396 0.014
positive regulation of secretion GO:0051047 116 0.014
immune effector process GO:0002252 159 0.013
interspecies interaction between organisms GO:0044419 156 0.013
regulation of interleukin 12 production GO:0032655 15 0.013
apoptotic signaling pathway GO:0097190 268 0.013
Human
centrosome organization GO:0051297 58 0.013
cellular response to dna damage stimulus GO:0006974 379 0.013
immune response GO:0006955 307 0.013
hematopoietic or lymphoid organ development GO:0048534 186 0.013
response to peptidoglycan GO:0032494 3 0.013
central nervous system development GO:0007417 123 0.013
negative regulation of protein phosphorylation GO:0001933 140 0.013
lipid modification GO:0030258 84 0.013
nucleoside triphosphate metabolic process GO:0009141 422 0.012
female gamete generation GO:0007292 2 0.012
cardiac muscle tissue development GO:0048738 39 0.012
leukocyte proliferation GO:0070661 74 0.012
cytoplasmic transport GO:0016482 379 0.012
regulation of viral entry into host cell GO:0046596 17 0.012
regulation of ligase activity GO:0051340 29 0.012
response to interferon alpha GO:0035455 11 0.012
lipid metabolic process GO:0006629 381 0.012
cardiovascular system development GO:0072358 262 0.012
ribonucleotide catabolic process GO:0009261 405 0.012
trna aminoacylation GO:0043039 12 0.012
protein processing GO:0016485 226 0.012
protein maturation GO:0051604 233 0.012
leukocyte activation GO:0045321 164 0.012
fat cell differentiation GO:0045444 32 0.012
defense response to other organism GO:0098542 129 0.011
negative regulation of protein processing GO:0010955 142 0.011
regulation of ion transport GO:0043269 189 0.011
natural killer cell mediated cytotoxicity GO:0042267 23 0.011
nucleoside monophosphate catabolic process GO:0009125 159 0.011
striated muscle cell differentiation GO:0051146 43 0.011
organelle assembly GO:0070925 176 0.011
basement membrane organization GO:0071711 3 0.011
base conversion or substitution editing GO:0016553 4 0.011
positive regulation of nucleotide catabolic process GO:0030813 185 0.011
single organism membrane organization GO:0044802 268 0.011
system process GO:0003008 349 0.011
cellular response to oxidative stress GO:0034599 85 0.011
vesicle mediated transport GO:0016192 371 0.010
muscle tissue development GO:0060537 62 0.010
cell growth GO:0016049 160 0.010
negative regulation of transport GO:0051051 176 0.010
regulation of protein export from nucleus GO:0046825 15 0.010
regulation of innate immune response GO:0045088 97 0.010
nucleoside monophosphate metabolic process GO:0009123 191 0.010
ribonucleoside monophosphate metabolic process GO:0009161 187 0.010

PSME1 disease predictions

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 155 0.081
musculoskeletal system disease DOID:17 223 0.025
primary immunodeficiency disease DOID:612 36 0.024
severe combined immunodeficiency DOID:627 10 0.024
combined t cell and b cell immunodeficiency DOID:628 12 0.024
bone disease DOID:0080001 88 0.014
connective tissue disease DOID:65 109 0.014