Homo sapiens

200 known processes

PMAIP1

phorbol-12-myristate-13-acetate-induced protein 1

(Aliases: APR,NOXA)

PMAIP1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
positive regulation of fibroblast apoptotic process GO:2000271 6 0.959
regulation of mitochondrion organization GO:0010821 54 0.873
regulation of protein oligomerization GO:0032459 26 0.873
regulation of mitochondrial membrane permeability involved in apoptotic process GO:1902108 18 0.871
Mouse
fibroblast apoptotic process GO:0044346 8 0.807
positive regulation of protein oligomerization GO:0032461 17 0.794
positive regulation of release of cytochrome c from mitochondria GO:0090200 18 0.754
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001240 16 0.749
apoptotic mitochondrial changes GO:0008637 57 0.744
positive regulation of apoptotic signaling pathway GO:2001235 70 0.736
negative regulation of cell proliferation GO:0008285 228 0.694
Mouse
positive regulation of intrinsic apoptotic signaling pathway GO:2001244 28 0.689
regulation of mitochondrial membrane permeability GO:0046902 25 0.681
mitochondrial outer membrane permeabilization involved in programmed cell death GO:1902686 16 0.675
Mouse
positive regulation of apoptotic process GO:0043065 246 0.655
positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway GO:1901030 3 0.647
Mouse
regulation of release of cytochrome c from mitochondria GO:0090199 29 0.631
negative regulation of programmed cell death GO:0043069 321 0.621
apoptotic signaling pathway GO:0097190 268 0.612
positive regulation of mitochondrion organization GO:0010822 30 0.605
mitochondrial membrane organization GO:0007006 40 0.601
positive regulation of programmed cell death GO:0043068 249 0.566
regulation of apoptotic signaling pathway GO:2001233 175 0.560
regulation of membrane permeability GO:0090559 25 0.555
mitochondrial transport GO:0006839 60 0.545
apoptotic process involved in morphogenesis GO:0060561 3 0.533
protein homooligomerization GO:0051260 100 0.528
positive regulation of protein homooligomerization GO:0032464 7 0.522
metal ion transport GO:0030001 272 0.518
modulation of programmed cell death in other organism GO:0044531 1 0.486
positive regulation of cell death GO:0010942 263 0.458
neuron death in response to oxidative stress GO:0036475 9 0.453
positive regulation of oxidative stress induced intrinsic apoptotic signaling pathway GO:1902177 4 0.452
release of cytochrome c from mitochondria GO:0001836 35 0.449
negative regulation of apoptotic signaling pathway GO:2001234 97 0.449
positive regulation of endoplasmic reticulum unfolded protein response GO:1900103 4 0.426
positive regulation of oxidative stress induced neuron intrinsic apoptotic signaling pathway GO:1903378 2 0.423
mitochondrion organization GO:0007005 156 0.421
zymogen activation GO:0031638 70 0.419
Mouse
positive regulation of oxidative stress induced cell death GO:1903209 5 0.416
regulation of protein homooligomerization GO:0032462 11 0.415
disruption of cells of other organism involved in symbiotic interaction GO:0051818 3 0.414
positive regulation of cysteine type endopeptidase activity GO:2001056 79 0.403
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 52 0.401
regulation of cysteine type endopeptidase activity GO:2000116 127 0.398
extrinsic apoptotic signaling pathway GO:0097191 119 0.374
protein insertion into mitochondrial membrane involved in apoptotic signaling pathway GO:0001844 2 0.361
Mouse
calcium ion transport GO:0006816 147 0.358
protein processing GO:0016485 226 0.336
Mouse
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 69 0.327
modulation of apoptotic process in other organism GO:0044532 1 0.326
activation of cysteine type endopeptidase activity involved in apoptotic process GO:0006919 49 0.322
Mouse
regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001239 20 0.318
regulation of oxidative stress induced neuron death GO:1903203 9 0.316
mitochondrial outer membrane permeabilization GO:0097345 15 0.310
Mouse
regulation of peptidase activity GO:0052547 180 0.309
regulation of killing of cells of other organism GO:0051709 4 0.307
positive regulation of mitochondrial membrane permeability GO:0035794 17 0.300
Mouse
negative regulation of apoptotic process GO:0043066 316 0.299
positive regulation of endopeptidase activity GO:0010950 84 0.292
lymphocyte homeostasis GO:0002260 4 0.289
Mouse
response to endoplasmic reticulum stress GO:0034976 49 0.289
regulation of proteolysis GO:0030162 293 0.274
modulation by organism of apoptotic process in other organism involved in symbiotic interaction GO:0052433 1 0.265
sequestering of metal ion GO:0051238 24 0.254
modulation of programmed cell death in other organism involved in symbiotic interaction GO:0052248 1 0.247
mitochondrial fragmentation involved in apoptotic process GO:0043653 7 0.246
protein polyubiquitination GO:0000209 110 0.239
negative regulation of mitotic cell cycle GO:0045930 102 0.237
positive regulation of protein complex assembly GO:0031334 86 0.235
regulation of endopeptidase activity GO:0052548 170 0.233
positive regulation of cellular component biogenesis GO:0044089 158 0.232
protein oligomerization GO:0051259 173 0.231
modulation by symbiont of host programmed cell death GO:0052040 1 0.224
post embryonic development GO:0009791 2 0.221
negative regulation of cellular component organization GO:0051129 235 0.217
multi organism cellular process GO:0044764 156 0.216
response to external biotic stimulus GO:0043207 261 0.211
b cell homeostasis GO:0001782 1 0.209
positive regulation of proteolysis GO:0045862 142 0.208
modulation by virus of host morphology or physiology GO:0019048 10 0.207
intrinsic apoptotic signaling pathway GO:0097193 127 0.200
cation transport GO:0006812 331 0.197
regulation of fibroblast apoptotic process GO:2000269 8 0.194
viral process GO:0016032 146 0.193
regulation of extrinsic apoptotic signaling pathway GO:2001236 85 0.193
cellular response to external stimulus GO:0071496 111 0.191
regulation of cellular component biogenesis GO:0044087 281 0.191
positive regulation of cellular component organization GO:0051130 376 0.190
modulation by symbiont of host apoptotic process GO:0052150 1 0.190
protein localization to membrane GO:0072657 160 0.189
Mouse
positive regulation of mitochondrial membrane permeability involved in apoptotic process GO:1902110 16 0.185
Mouse
intrinsic apoptotic signaling pathway in response to oxidative stress GO:0008631 21 0.184
protein maturation GO:0051604 233 0.183
Mouse
divalent metal ion transport GO:0070838 152 0.182
regulation of homeostatic process GO:0032844 121 0.178
regulation of execution phase of apoptosis GO:1900117 11 0.177
cellular homeostasis GO:0019725 196 0.176
t cell homeostasis GO:0043029 3 0.174
Mouse
regulation of response to dna damage stimulus GO:2001020 94 0.170
execution phase of apoptosis GO:0097194 32 0.166
regulation of cellular amine metabolic process GO:0033238 11 0.162
guanosine containing compound catabolic process GO:1901069 239 0.160
membrane fusion GO:0061025 43 0.160
immune response activating signal transduction GO:0002757 90 0.160
immune response activating cell surface receptor signaling pathway GO:0002429 45 0.158
developmental programmed cell death GO:0010623 3 0.157
activation of cysteine type endopeptidase activity involved in apoptotic process by cytochrome c GO:0008635 2 0.157
ribonucleoside triphosphate catabolic process GO:0009203 391 0.156
regulation of mitochondrial fusion GO:0010635 5 0.154
regeneration GO:0031099 4 0.154
signal transduction in absence of ligand GO:0038034 22 0.153
response to other organism GO:0051707 261 0.153
positive regulation of killing of cells of other organism GO:0051712 4 0.153
cellular ion homeostasis GO:0006873 168 0.149
response to organic cyclic compound GO:0014070 204 0.147
patterning of blood vessels GO:0001569 2 0.144
regulation of protein complex assembly GO:0043254 147 0.144
response to biotic stimulus GO:0009607 276 0.142
myeloid cell homeostasis GO:0002262 34 0.142
cell adhesion GO:0007155 325 0.139
interspecies interaction between organisms GO:0044419 156 0.139
positive regulation of response to oxidative stress GO:1902884 7 0.137
positive regulation of hydrolase activity GO:0051345 331 0.136
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 22 0.135
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.134
modulation by symbiont of host cellular process GO:0044068 3 0.133
thymus development GO:0048538 3 0.133
transmembrane transport GO:0055085 399 0.132
mitochondrial fusion GO:0008053 13 0.132
membrane organization GO:0061024 292 0.130
activation of immune response GO:0002253 114 0.129
protein ubiquitination GO:0016567 314 0.129
single organism membrane organization GO:0044802 268 0.128
cellular cation homeostasis GO:0030003 163 0.128
negative regulation of cell cycle GO:0045786 193 0.127
positive regulation of developmental process GO:0051094 314 0.122
regulation of cell differentiation GO:0045595 393 0.121
regulation of anatomical structure morphogenesis GO:0022603 286 0.120
growth GO:0040007 202 0.120
nucleic acid phosphodiester bond hydrolysis GO:0090305 102 0.120
negative regulation of catalytic activity GO:0043086 335 0.119
modulation by virus of host process GO:0019054 2 0.119
negative regulation of protein metabolic process GO:0051248 391 0.117
regulation of cellular ph reduction GO:0032847 1 0.117
regulation of oxidative stress induced intrinsic apoptotic signaling pathway GO:1902175 16 0.115
negative regulation of cell death GO:0060548 345 0.114
regulation of intrinsic apoptotic signaling pathway GO:2001242 72 0.113
urogenital system development GO:0001655 65 0.113
cellular calcium ion homeostasis GO:0006874 117 0.113
biological adhesion GO:0022610 331 0.109
ribonucleoside triphosphate metabolic process GO:0009199 412 0.109
sequestering of calcium ion GO:0051208 17 0.108
positive regulation of peptidase activity GO:0010952 88 0.106
regulation of ion transport GO:0043269 189 0.105
regulation of cellular response to stress GO:0080135 244 0.105
positive regulation of dna metabolic process GO:0051054 73 0.105
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress GO:0070059 12 0.105
kidney development GO:0001822 53 0.103
mitotic cell cycle phase transition GO:0044772 162 0.102
defense response GO:0006952 315 0.101
thymocyte apoptotic process GO:0070242 2 0.100
modification of morphology or physiology of other organism GO:0035821 43 0.100
divalent inorganic cation homeostasis GO:0072507 136 0.098
regulation of mitotic cell cycle phase transition GO:1901990 118 0.097
regulation of ion homeostasis GO:2000021 73 0.097
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.096
regulation of calcium ion transport GO:0051924 79 0.096
regulation of endoplasmic reticulum unfolded protein response GO:1900101 5 0.095
transformed cell apoptotic process GO:0006927 3 0.094
extrinsic apoptotic signaling pathway via death domain receptors GO:0008625 42 0.093
response to virus GO:0009615 126 0.090
mitotic cell cycle process GO:1903047 286 0.089
lymphocyte apoptotic process GO:0070227 20 0.088
regulation of reactive oxygen species metabolic process GO:2000377 41 0.087
interaction with host GO:0051701 42 0.087
negative regulation of cellular protein metabolic process GO:0032269 353 0.087
positive regulation of organelle organization GO:0010638 195 0.087
regulation of mitotic cell cycle GO:0007346 189 0.087
regulation of apoptotic dna fragmentation GO:1902510 3 0.087
glycosyl compound catabolic process GO:1901658 413 0.086
regulation of cell cycle process GO:0010564 266 0.086
neuron intrinsic apoptotic signaling pathway in response to oxidative stress GO:0036480 7 0.085
cellular amine metabolic process GO:0044106 41 0.085
immune response regulating signaling pathway GO:0002764 97 0.085
anatomical structure formation involved in morphogenesis GO:0048646 284 0.084
renal system development GO:0072001 63 0.084
establishment of protein localization to membrane GO:0090150 121 0.083
Mouse
nitrogen compound transport GO:0071705 191 0.083
regulation of establishment of protein localization GO:0070201 242 0.082
Mouse
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.082
purine nucleoside catabolic process GO:0006152 398 0.081
immune response GO:0006955 307 0.079
positive regulation of cellular catabolic process GO:0031331 284 0.078
positive regulation of catabolic process GO:0009896 310 0.078
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 109 0.078
lymphocyte activation GO:0046649 133 0.077
activation of cysteine type endopeptidase activity GO:0097202 57 0.077
Mouse
positive regulation of cellular response to oxidative stress GO:1900409 7 0.077
immune response regulating cell surface receptor signaling pathway GO:0002768 51 0.077
regulation of protein binding GO:0043393 66 0.076
purine nucleoside triphosphate catabolic process GO:0009146 392 0.076
regulation of membrane potential GO:0042391 95 0.076
Mouse
nucleoside triphosphate metabolic process GO:0009141 422 0.075
hematopoietic or lymphoid organ development GO:0048534 186 0.075
ossification GO:0001503 121 0.075
negative regulation of signal transduction in absence of ligand GO:1901099 16 0.075
cell type specific apoptotic process GO:0097285 125 0.074
Mouse
muscle tissue development GO:0060537 62 0.074
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.073
dna catabolic process endonucleolytic GO:0000737 37 0.072
single organism membrane fusion GO:0044801 37 0.072
regulation of protein localization to plasma membrane GO:1903076 40 0.071
cell division GO:0051301 168 0.071
negative regulation of cell cycle process GO:0010948 121 0.070
regulation of cellular amino acid metabolic process GO:0006521 6 0.070
negative regulation of protein phosphorylation GO:0001933 140 0.070
morphogenesis of embryonic epithelium GO:0016331 4 0.070
positive regulation of dna catabolic process GO:1903626 2 0.068
response to abiotic stimulus GO:0009628 336 0.068
regulation of oxidative stress induced neuron intrinsic apoptotic signaling pathway GO:1903376 7 0.068
epithelial cell proliferation GO:0050673 128 0.067
purine ribonucleoside metabolic process GO:0046128 437 0.066
defense response to other organism GO:0098542 129 0.066
guanosine containing compound metabolic process GO:1901068 244 0.066
cardiovascular system development GO:0072358 262 0.066
negative regulation of organelle organization GO:0010639 126 0.065
regulation of oxidative stress induced cell death GO:1903201 24 0.064
ribonucleotide catabolic process GO:0009261 405 0.064
regulation of transmembrane transporter activity GO:0022898 74 0.063
metal ion homeostasis GO:0055065 169 0.062
regulation of mitochondrial membrane potential GO:0051881 23 0.062
Mouse
negative regulation of homeostatic process GO:0032845 59 0.061
regulation of cellular component movement GO:0051270 334 0.061
negative regulation of hydrolase activity GO:0051346 182 0.059
protein modification by small protein conjugation GO:0032446 342 0.058
purine nucleoside triphosphate metabolic process GO:0009144 412 0.058
positive regulation of nucleotide metabolic process GO:0045981 230 0.058
defense response to virus GO:0051607 71 0.058
immune effector process GO:0002252 159 0.058
regulation of cell growth GO:0001558 135 0.057
regulation of multi organism process GO:0043900 157 0.057
regulation of dna metabolic process GO:0051052 153 0.057
homeostasis of number of cells GO:0048872 40 0.056
Mouse
cell cycle phase transition GO:0044770 173 0.056
epithelium development GO:0060429 227 0.056
divalent inorganic cation transport GO:0072511 158 0.055
antigen receptor mediated signaling pathway GO:0050851 38 0.055
purine ribonucleotide catabolic process GO:0009154 404 0.055
er nucleus signaling pathway GO:0006984 23 0.054
regulation of epithelial cell proliferation GO:0050678 113 0.053
response to axon injury GO:0048678 1 0.053
cell matrix adhesion GO:0007160 85 0.053
negative regulation by symbiont of host apoptotic process GO:0033668 1 0.052
regulation of growth GO:0040008 165 0.052
mitotic cell cycle GO:0000278 326 0.052
regulation of cell killing GO:0031341 22 0.051
negative regulation of intracellular signal transduction GO:1902532 183 0.051
negative regulation of cell differentiation GO:0045596 171 0.051
b cell activation GO:0042113 33 0.051
cellular amino acid metabolic process GO:0006520 116 0.051
cytosolic calcium ion homeostasis GO:0051480 89 0.050
liposaccharide metabolic process GO:1903509 27 0.050
positive regulation of apoptotic process involved in mammary gland involution GO:0060058 1 0.050
endoplasmic reticulum unfolded protein response GO:0030968 16 0.050
leukocyte apoptotic process GO:0071887 31 0.050
negative regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043154 46 0.050
negative regulation of protein maturation GO:1903318 142 0.050
modification of morphology or physiology of other organism involved in symbiotic interaction GO:0051817 38 0.049
oxidation reduction process GO:0055114 396 0.049
positive regulation of execution phase of apoptosis GO:1900119 5 0.049
lytic vacuole organization GO:0080171 24 0.048
modification by symbiont of host morphology or physiology GO:0044003 12 0.048
immune system development GO:0002520 195 0.048
positive regulation of muscle cell differentiation GO:0051149 15 0.048
embryonic digit morphogenesis GO:0042733 6 0.047
cation homeostasis GO:0055080 189 0.047
cellular response to oxygen levels GO:0071453 55 0.047
response to wounding GO:0009611 168 0.046
cytokine production GO:0001816 247 0.046
nucleotide catabolic process GO:0009166 408 0.046
tube development GO:0035295 125 0.046
regulation of metal ion transport GO:0010959 120 0.046
t cell apoptotic process GO:0070231 12 0.046
negative regulation of developmental process GO:0051093 247 0.046
protein catabolic process GO:0030163 325 0.045
regulation of mitosis GO:0007088 63 0.045
organ morphogenesis GO:0009887 147 0.045
cellular response to dna damage stimulus GO:0006974 379 0.045
negative regulation of protein modification process GO:0031400 200 0.044
carbohydrate derivative biosynthetic process GO:1901137 207 0.044
calcium ion homeostasis GO:0055074 122 0.043
glycoprotein biosynthetic process GO:0009101 91 0.043
nervous system development GO:0007399 293 0.043
regulation of cell cycle phase transition GO:1901987 126 0.043
regulation of immune response GO:0050776 201 0.043
regulation of purine nucleotide metabolic process GO:1900542 264 0.043
response to alkaloid GO:0043279 20 0.043
regulation of cell development GO:0060284 161 0.042
regulation of nucleotide metabolic process GO:0006140 269 0.042
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 40 0.042
positive regulation of apoptotic process involved in morphogenesis GO:1902339 1 0.042
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.042
positive regulation of leukocyte proliferation GO:0070665 48 0.042
killing of cells in other organism involved in symbiotic interaction GO:0051883 3 0.042
carbohydrate metabolic process GO:0005975 207 0.042
positive regulation of nucleoside metabolic process GO:0045979 186 0.041
regulation of cell cycle GO:0051726 393 0.041
positive regulation of homeostatic process GO:0032846 47 0.041
leukocyte differentiation GO:0002521 98 0.041
fear response GO:0042596 0 0.040
gtp metabolic process GO:0046039 239 0.040
negative regulation of proteolysis GO:0045861 132 0.040
peptidyl serine modification GO:0018209 106 0.040
positive regulation of cell proliferation GO:0008284 301 0.040
regulation of cellular ketone metabolic process GO:0010565 50 0.039
cellular macromolecule catabolic process GO:0044265 380 0.039
positive regulation of lymphocyte proliferation GO:0050671 46 0.038
cell development GO:0048468 328 0.038
positive regulation of apoptotic dna fragmentation GO:1902512 1 0.038
pigment granule organization GO:0048753 7 0.037
response to topologically incorrect protein GO:0035966 29 0.037
organelle fusion GO:0048284 36 0.037
t cell activation GO:0042110 99 0.036
regulation of leukocyte activation GO:0002694 115 0.036
organophosphate catabolic process GO:0046434 430 0.036
embryonic epithelial tube formation GO:0001838 4 0.036
positive regulation of immune system process GO:0002684 283 0.036
regulation of protein heterodimerization activity GO:0043497 5 0.036
regulation of transmembrane transport GO:0034762 139 0.036
regulation of purine nucleotide catabolic process GO:0033121 205 0.035
regulation of protein processing GO:0070613 150 0.035
negative regulation of execution phase of apoptosis GO:1900118 6 0.035
negative regulation of peptidase activity GO:0010466 91 0.035
cellular response to uv GO:0034644 32 0.035
negative regulation of anoikis GO:2000811 15 0.034
cellular component disassembly GO:0022411 92 0.034
response to organonitrogen compound GO:0010243 156 0.034
positive regulation of neuron apoptotic process GO:0043525 8 0.034
Mouse
camp metabolic process GO:0046058 61 0.034
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.034
modulation by virus of host apoptotic process GO:0039526 1 0.034
positive regulation of neuron death GO:1901216 14 0.033
Mouse
negative regulation by organism of programmed cell death in other organism involved in symbiotic interaction GO:0052490 1 0.033
response to metal ion GO:0010038 84 0.033
female gamete generation GO:0007292 2 0.033
release of matrix enzymes from mitochondria GO:0032976 1 0.033
regulation of cell motility GO:2000145 299 0.032
response to drug GO:0042493 81 0.032
limbic system development GO:0021761 3 0.032
ribonucleoside catabolic process GO:0042454 406 0.031
positive regulation of extrinsic apoptotic signaling pathway GO:2001238 26 0.031
inflammatory response GO:0006954 79 0.031
response to cytokine GO:0034097 232 0.031
central nervous system development GO:0007417 123 0.031
positive regulation of cytokine production GO:0001819 167 0.030
oogenesis GO:0048477 2 0.030
multicellular organismal aging GO:0010259 3 0.030
positive regulation of developmental pigmentation GO:0048087 2 0.030
cytoplasmic transport GO:0016482 379 0.030
regulation of protein localization GO:0032880 296 0.030
Mouse
cofactor metabolic process GO:0051186 87 0.030
purine nucleotide catabolic process GO:0006195 405 0.030
spleen development GO:0048536 1 0.030
positive regulation of cytosolic calcium ion concentration GO:0007204 82 0.030
muscle cell differentiation GO:0042692 63 0.030
response to radiation GO:0009314 151 0.030
Mouse
regulation of protein kinase activity GO:0045859 289 0.029
cd8 positive alpha beta t cell activation GO:0036037 3 0.029
positive regulation of cell activation GO:0050867 81 0.029
negative regulation of protein binding GO:0032091 35 0.029
negative regulation of transferase activity GO:0051348 124 0.029
neural tube formation GO:0001841 3 0.028
regulation of transferase activity GO:0051338 355 0.028
nucleoside catabolic process GO:0009164 408 0.028
response to mechanical stimulus GO:0009612 51 0.028
regulation of nuclear division GO:0051783 65 0.028
response to light stimulus GO:0009416 87 0.028
Mouse
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 50 0.028
Mouse
nucleoside triphosphate catabolic process GO:0009143 394 0.027
blood vessel development GO:0001568 172 0.027
angiogenesis GO:0001525 147 0.027
reactive oxygen species metabolic process GO:0072593 75 0.027
regulation of response to external stimulus GO:0032101 222 0.026
regulation of protein maturation GO:1903317 150 0.026
negative regulation of phosphate metabolic process GO:0045936 267 0.026
regulation of lymphocyte activation GO:0051249 103 0.026
development of primary male sexual characteristics GO:0046546 23 0.026
negative regulation of multicellular organismal process GO:0051241 317 0.026
negative regulation of binding GO:0051100 57 0.026
purine ribonucleoside catabolic process GO:0046130 398 0.026
regulation of gtpase activity GO:0043087 180 0.026
positive regulation of lymphocyte activation GO:0051251 73 0.025
positive regulation of oxidative stress induced neuron death GO:1903223 2 0.025
regulation of cell migration GO:0030334 289 0.025
positive regulation of transport GO:0051050 336 0.025
Mouse
male sex differentiation GO:0046661 25 0.025
positive regulation of gtpase activity GO:0043547 166 0.025
neuron apoptotic process GO:0051402 39 0.025
Mouse
gtp catabolic process GO:0006184 237 0.025
tissue regeneration GO:0042246 3 0.025
cellular metal ion homeostasis GO:0006875 146 0.025
cellular component morphogenesis GO:0032989 314 0.024
tripartite regional subdivision GO:0007351 2 0.024
spermatid differentiation GO:0048515 4 0.024
regulation of cell division GO:0051302 116 0.024
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.024
negative regulation of cell growth GO:0030308 83 0.024
regulation of transporter activity GO:0032409 82 0.024
cellular lipid metabolic process GO:0044255 303 0.024
response to lipid GO:0033993 206 0.023
establishment or maintenance of transmembrane electrochemical gradient GO:0010248 2 0.023
pigmentation GO:0043473 22 0.023
odontogenesis GO:0042476 25 0.023
microtubule cytoskeleton organization GO:0000226 176 0.023
oocyte differentiation GO:0009994 2 0.023
response to nitrogen compound GO:1901698 184 0.023
organic hydroxy compound metabolic process GO:1901615 147 0.023
positive regulation of cellular amine metabolic process GO:0033240 7 0.023
regulation of lymphocyte proliferation GO:0050670 64 0.023
protein k48 linked ubiquitination GO:0070936 38 0.023
organonitrogen compound biosynthetic process GO:1901566 200 0.023
rna processing GO:0006396 255 0.023
positive regulation of cell differentiation GO:0045597 211 0.023
circulatory system development GO:0072359 262 0.023
cell projection organization GO:0030030 252 0.022
multicellular organismal homeostasis GO:0048871 67 0.022
negative regulation of phosphorus metabolic process GO:0010563 267 0.022
suppression by virus of host apoptotic process GO:0019050 1 0.022
positive regulation of cell killing GO:0031343 19 0.022
regulation of binding GO:0051098 111 0.022
cellular protein catabolic process GO:0044257 261 0.022
cellular divalent inorganic cation homeostasis GO:0072503 128 0.021
negative regulation of phosphorylation GO:0042326 174 0.021
intracellular protein transport GO:0006886 270 0.021
protein insertion into mitochondrial membrane GO:0051204 3 0.021
Mouse
regulation of intrinsic apoptotic signaling pathway in response to dna damage GO:1902229 20 0.021
hemopoiesis GO:0030097 180 0.021
cellular monovalent inorganic cation homeostasis GO:0030004 26 0.021
negative regulation of cell division GO:0051782 31 0.021
mitotic nuclear division GO:0007067 119 0.021
locomotory behavior GO:0007626 1 0.021
protein localization to mitochondrion GO:0070585 25 0.021
Mouse
positive regulation of cell growth GO:0030307 48 0.021
muscle structure development GO:0061061 98 0.020
histone ubiquitination GO:0016574 31 0.020
generation of neurons GO:0048699 152 0.020
metencephalon development GO:0022037 2 0.020
negative regulation of locomotion GO:0040013 118 0.020
melanin metabolic process GO:0006582 1 0.020
cellular response to starvation GO:0009267 58 0.020
cell activation GO:0001775 213 0.020
regulation of leukocyte proliferation GO:0070663 67 0.020
response to tumor necrosis factor GO:0034612 76 0.020
determination of adult lifespan GO:0008340 2 0.020
developmental growth GO:0048589 48 0.020
response to nitrosative stress GO:0051409 4 0.020
negative regulation of protein serine threonine kinase activity GO:0071901 57 0.020
b cell apoptotic process GO:0001783 6 0.020
response to uv GO:0009411 73 0.020
Mouse
tube morphogenesis GO:0035239 95 0.020
cellular response to light stimulus GO:0071482 34 0.019
nucleoside phosphate catabolic process GO:1901292 412 0.019
negative regulation of protein processing GO:0010955 142 0.019
regulation of cell projection organization GO:0031344 107 0.019
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.019
regulation of neural precursor cell proliferation GO:2000177 4 0.019
regulation of b cell proliferation GO:0030888 18 0.019
coenzyme metabolic process GO:0006732 65 0.019
establishment or maintenance of cytoskeleton polarity GO:0030952 3 0.019
apoptotic dna fragmentation GO:0006309 6 0.019
reactive oxygen species biosynthetic process GO:1903409 4 0.019
single organism cellular localization GO:1902580 332 0.019
Mouse
anatomical structure homeostasis GO:0060249 100 0.019
cell growth GO:0016049 160 0.018
negative regulation of axonogenesis GO:0050771 4 0.018
positive regulation of gtp catabolic process GO:0033126 166 0.018
blastoderm segmentation GO:0007350 2 0.018
neuron death GO:0070997 65 0.018
Mouse
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.018
apoptotic nuclear changes GO:0030262 13 0.018
peptidyl tyrosine dephosphorylation GO:0035335 36 0.018
neurotransmitter secretion GO:0007269 4 0.018
negative regulation of cellular amine metabolic process GO:0033239 3 0.018
positive regulation of immune response GO:0050778 159 0.018
regulation of muscle cell differentiation GO:0051147 31 0.018
cellular response to extracellular stimulus GO:0031668 72 0.018
membrane lipid metabolic process GO:0006643 53 0.018
regulation of myeloid cell differentiation GO:0045637 81 0.018
somatic muscle development GO:0007525 1 0.018
cell killing GO:0001906 34 0.017
release of sequestered calcium ion into cytosol GO:0051209 41 0.017

PMAIP1 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 174 0.055
gastrointestinal system cancer DOID:3119 52 0.051
cancer DOID:162 167 0.051
organ system cancer DOID:0050686 164 0.051