Homo sapiens

41 known processes

PTGS1

prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)

(Aliases: PGHS-1,PGHS1,COX3,COX1,PGG/HS,PTGHS,PHS1,PCOX1)

PTGS1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cellular amino acid metabolic process GO:0006520 116 0.274
regulation of cellular ketone metabolic process GO:0010565 50 0.237
regulation of cellular amine metabolic process GO:0033238 11 0.235
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.216
cellular amine metabolic process GO:0044106 41 0.201
cellular ketone metabolic process GO:0042180 80 0.194
defense response GO:0006952 315 0.191
positive regulation of cellular amine metabolic process GO:0033240 7 0.171
regulation of cellular amino acid metabolic process GO:0006521 6 0.157
amine metabolic process GO:0009308 44 0.142
response to oxygen containing compound GO:1901700 369 0.138
Rat
lipid metabolic process GO:0006629 381 0.134
positive regulation of protein phosphorylation GO:0001934 313 0.127
response to abiotic stimulus GO:0009628 336 0.126
Human
positive regulation of phosphorylation GO:0042327 394 0.123
cation transport GO:0006812 331 0.121
cytokine production GO:0001816 247 0.105
regulation of cell adhesion GO:0030155 166 0.103
regulation of locomotion GO:0040012 329 0.102
biological adhesion GO:0022610 331 0.101
blood vessel development GO:0001568 172 0.098
Zebrafish
vasculature development GO:0001944 181 0.095
Zebrafish
positive regulation of hydrolase activity GO:0051345 331 0.094
regulation of response to external stimulus GO:0032101 222 0.094
cellular response to endogenous stimulus GO:0071495 336 0.092
regulation of anatomical structure morphogenesis GO:0022603 286 0.092
regulation of angiogenesis GO:0045765 92 0.092
positive regulation of transport GO:0051050 336 0.091
monocarboxylic acid metabolic process GO:0032787 185 0.091
circulatory system development GO:0072359 262 0.090
Zebrafish
cellular lipid metabolic process GO:0044255 303 0.089
vesicle mediated transport GO:0016192 371 0.086
response to other organism GO:0051707 261 0.086
regulation of cell migration GO:0030334 289 0.086
response to wounding GO:0009611 168 0.085
blood vessel morphogenesis GO:0048514 162 0.084
Zebrafish
small molecule biosynthetic process GO:0044283 157 0.079
response to biotic stimulus GO:0009607 276 0.078
response to external biotic stimulus GO:0043207 261 0.077
post embryonic development GO:0009791 2 0.077
anatomical structure formation involved in morphogenesis GO:0048646 284 0.075
response to lipid GO:0033993 206 0.074
Rat
regulation of cellular component movement GO:0051270 334 0.074
regulation of cytokine production GO:0001817 232 0.074
negative regulation of multicellular organismal process GO:0051241 317 0.073
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.073
purine ribonucleotide catabolic process GO:0009154 404 0.073
regulation of transferase activity GO:0051338 355 0.073
organophosphate catabolic process GO:0046434 430 0.073
positive regulation of cytokine production GO:0001819 167 0.072
cell adhesion GO:0007155 325 0.070
positive regulation of cellular component organization GO:0051130 376 0.070
small gtpase mediated signal transduction GO:0007264 78 0.069
transmembrane transport GO:0055085 399 0.069
positive regulation of immune system process GO:0002684 283 0.069
wound healing GO:0042060 115 0.068
response to cytokine GO:0034097 232 0.067
secretion by cell GO:0032940 226 0.067
Rat
nucleotide catabolic process GO:0009166 408 0.067
lipid biosynthetic process GO:0008610 177 0.067
glycosyl compound catabolic process GO:1901658 413 0.066
purine containing compound catabolic process GO:0072523 411 0.066
ribonucleoside triphosphate catabolic process GO:0009203 391 0.065
purine nucleotide catabolic process GO:0006195 405 0.065
ras protein signal transduction GO:0007265 73 0.064
regulation of protein kinase activity GO:0045859 289 0.064
purine nucleoside catabolic process GO:0006152 398 0.064
purine nucleoside triphosphate metabolic process GO:0009144 412 0.063
response to growth factor GO:0070848 205 0.063
metal ion transport GO:0030001 272 0.062
regulation of cellular component biogenesis GO:0044087 281 0.062
rho protein signal transduction GO:0007266 26 0.062
positive regulation of protein kinase activity GO:0045860 190 0.060
regulation of defense response GO:0031347 154 0.059
nucleoside catabolic process GO:0009164 408 0.059
cellular response to oxygen containing compound GO:1901701 276 0.059
regulation of response to wounding GO:1903034 101 0.058
ribonucleoside catabolic process GO:0042454 406 0.058
positive regulation of kinase activity GO:0033674 204 0.058
regulation of purine nucleotide metabolic process GO:1900542 264 0.057
membrane organization GO:0061024 292 0.057
inflammatory response GO:0006954 79 0.056
chemical homeostasis GO:0048878 306 0.055
immune response GO:0006955 307 0.055
ribonucleotide catabolic process GO:0009261 405 0.055
regulation of nucleotide metabolic process GO:0006140 269 0.055
positive regulation of developmental process GO:0051094 314 0.055
angiogenesis GO:0001525 147 0.054
ribonucleoside triphosphate metabolic process GO:0009199 412 0.054
positive regulation of mapk cascade GO:0043410 190 0.053
nucleoside triphosphate metabolic process GO:0009141 422 0.053
negative regulation of catalytic activity GO:0043086 335 0.053
response to molecule of bacterial origin GO:0002237 82 0.053
nucleoside triphosphate catabolic process GO:0009143 394 0.053
purine ribonucleoside catabolic process GO:0046130 398 0.052
female gamete generation GO:0007292 2 0.052
purine ribonucleoside metabolic process GO:0046128 437 0.052
regulation of cell motility GO:2000145 299 0.051
signal transduction by phosphorylation GO:0023014 297 0.050
negative regulation of phosphate metabolic process GO:0045936 267 0.050
purine nucleoside triphosphate catabolic process GO:0009146 392 0.049
regulation of vasculature development GO:1901342 97 0.049
negative regulation of programmed cell death GO:0043069 321 0.048
apoptotic signaling pathway GO:0097190 268 0.048
positive regulation of transferase activity GO:0051347 227 0.048
regulation of apoptotic signaling pathway GO:2001233 175 0.047
system process GO:0003008 349 0.047
Mouse Rat
response to organic cyclic compound GO:0014070 204 0.047
Zebrafish Rat
regulation of establishment of protein localization GO:0070201 242 0.047
mapk cascade GO:0000165 288 0.047
positive regulation of cell migration GO:0030335 172 0.047
positive regulation of nucleotide metabolic process GO:0045981 230 0.047
regulation of kinase activity GO:0043549 314 0.047
regulation of body fluid levels GO:0050878 99 0.047
blood coagulation GO:0007596 76 0.046
single organism cellular localization GO:1902580 332 0.046
protein maturation GO:0051604 233 0.046
nucleoside phosphate catabolic process GO:1901292 412 0.046
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.045
actin filament based process GO:0030029 224 0.045
positive regulation of cell death GO:0010942 263 0.045
positive regulation of cell motility GO:2000147 177 0.044
cellular response to growth factor stimulus GO:0071363 197 0.044
cellular chemical homeostasis GO:0055082 180 0.044
positive regulation of protein transport GO:0051222 135 0.044
peptidyl tyrosine modification GO:0018212 170 0.044
guanosine containing compound metabolic process GO:1901068 244 0.044
negative regulation of developmental process GO:0051093 247 0.044
coagulation GO:0050817 78 0.044
negative regulation of cellular protein metabolic process GO:0032269 353 0.044
regulation of nucleotide catabolic process GO:0030811 205 0.043
cellular response to cytokine stimulus GO:0071345 181 0.043
positive regulation of cell proliferation GO:0008284 301 0.043
ion transmembrane transport GO:0034220 338 0.043
nitrogen compound transport GO:0071705 191 0.043
Rat
cytoplasmic transport GO:0016482 379 0.042
response to hormone GO:0009725 175 0.042
Rat
regulation of cell differentiation GO:0045595 393 0.042
negative regulation of apoptotic process GO:0043066 316 0.042
fatty acid metabolic process GO:0006631 115 0.042
cell morphogenesis GO:0000902 296 0.041
cardiovascular system development GO:0072358 262 0.041
Zebrafish
regulation of proteolysis GO:0030162 293 0.041
negative regulation of cell death GO:0060548 345 0.041
single organism membrane organization GO:0044802 268 0.041
negative regulation of cell proliferation GO:0008285 228 0.040
negative regulation of protein metabolic process GO:0051248 391 0.040
carboxylic acid biosynthetic process GO:0046394 97 0.040
cellular ion homeostasis GO:0006873 168 0.040
negative regulation of cellular component movement GO:0051271 106 0.040
regulation of intracellular transport GO:0032386 195 0.040
regulation of protein localization GO:0032880 296 0.039
determination of adult lifespan GO:0008340 2 0.039
actin cytoskeleton organization GO:0030036 207 0.039
response to organonitrogen compound GO:0010243 156 0.039
Rat
cation homeostasis GO:0055080 189 0.039
regulation of cellular response to stress GO:0080135 244 0.039
endothelial cell migration GO:0043542 86 0.039
negative regulation of hydrolase activity GO:0051346 182 0.039
regeneration GO:0031099 4 0.039
cell substrate adhesion GO:0031589 132 0.039
regulation of protein transport GO:0051223 213 0.038
response to bacterium GO:0009617 144 0.038
regulation of peptidase activity GO:0052547 180 0.038
epithelium migration GO:0090132 119 0.038
negative regulation of cellular component organization GO:0051129 235 0.038
divalent inorganic cation transport GO:0072511 158 0.038
positive regulation of cell differentiation GO:0045597 211 0.037
enzyme linked receptor protein signaling pathway GO:0007167 303 0.037
g protein coupled receptor signaling pathway GO:0007186 207 0.037
negative regulation of phosphorus metabolic process GO:0010563 267 0.037
response to inorganic substance GO:0010035 127 0.037
multicellular organismal aging GO:0010259 3 0.037
regulation of epithelial cell migration GO:0010632 93 0.036
positive regulation of catabolic process GO:0009896 310 0.036
positive regulation of angiogenesis GO:0045766 51 0.036
ameboidal type cell migration GO:0001667 135 0.036
regulation of ras protein signal transduction GO:0046578 155 0.036
protein oligomerization GO:0051259 173 0.036
regulation of mapk cascade GO:0043408 262 0.035
guanosine containing compound catabolic process GO:1901069 239 0.035
single organism cell adhesion GO:0098602 179 0.035
extrinsic apoptotic signaling pathway GO:0097191 119 0.034
oogenesis GO:0048477 2 0.034
immune effector process GO:0002252 159 0.034
secretion GO:0046903 254 0.034
Rat
cellular homeostasis GO:0019725 196 0.034
cellular divalent inorganic cation homeostasis GO:0072503 128 0.034
cellular component morphogenesis GO:0032989 314 0.034
negative regulation of locomotion GO:0040013 118 0.034
positive regulation of apoptotic process GO:0043065 246 0.034
gtp metabolic process GO:0046039 239 0.034
cell matrix adhesion GO:0007160 85 0.033
nervous system development GO:0007399 293 0.033
organic acid biosynthetic process GO:0016053 97 0.033
positive regulation of cellular catabolic process GO:0031331 284 0.033
cyclic nucleotide metabolic process GO:0009187 82 0.033
innate immune response GO:0045087 178 0.033
ion homeostasis GO:0050801 230 0.033
epithelial cell proliferation GO:0050673 128 0.032
hemostasis GO:0007599 76 0.032
epithelial cell migration GO:0010631 119 0.032
regulation of epithelial cell proliferation GO:0050678 113 0.032
regulation of blood coagulation GO:0030193 42 0.031
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.031
positive regulation of programmed cell death GO:0043068 249 0.031
positive regulation of nucleoside metabolic process GO:0045979 186 0.031
intracellular protein transport GO:0006886 270 0.031
protein processing GO:0016485 226 0.031
memory GO:0007613 3 0.031
Rat
regulation of reactive oxygen species metabolic process GO:2000377 41 0.031
divalent metal ion transport GO:0070838 152 0.030
metal ion homeostasis GO:0055065 169 0.030
positive regulation of response to external stimulus GO:0032103 88 0.030
organ morphogenesis GO:0009887 147 0.030
leukocyte migration GO:0050900 107 0.030
cell activation GO:0001775 213 0.030
regulation of protein processing GO:0070613 150 0.030
positive regulation of locomotion GO:0040017 186 0.030
regulation of purine nucleotide catabolic process GO:0033121 205 0.030
calcium ion transport GO:0006816 147 0.030
regulation of cell cycle GO:0051726 393 0.030
regulation of extrinsic apoptotic signaling pathway GO:2001236 85 0.030
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 85 0.030
segmentation GO:0035282 4 0.029
positive regulation of gtpase activity GO:0043547 166 0.029
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.029
taxis GO:0042330 157 0.029
response to nitrogen compound GO:1901698 184 0.029
Rat
response to oxygen levels GO:0070482 100 0.028
Human
negative regulation of cell motility GO:2000146 104 0.028
endocytosis GO:0006897 159 0.028
regulation of gtpase activity GO:0043087 180 0.028
positive regulation of cellular component biogenesis GO:0044089 158 0.028
regulation of ion transport GO:0043269 189 0.028
regulation of multi organism process GO:0043900 157 0.027
gtp catabolic process GO:0006184 237 0.027
tissue morphogenesis GO:0048729 96 0.027
regulation of protein serine threonine kinase activity GO:0071900 179 0.027
activation of protein kinase activity GO:0032147 90 0.027
regulation of immune response GO:0050776 201 0.027
positive regulation of immune response GO:0050778 159 0.027
unsaturated fatty acid metabolic process GO:0033559 37 0.027
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.027
single organismal cell cell adhesion GO:0016337 148 0.027
positive regulation of nucleotide catabolic process GO:0030813 185 0.026
reactive oxygen species metabolic process GO:0072593 75 0.026
response to virus GO:0009615 126 0.026
neurological system process GO:0050877 163 0.026
Rat
carbohydrate derivative biosynthetic process GO:1901137 207 0.026
defense response to other organism GO:0098542 129 0.026
positive regulation of gtp catabolic process GO:0033126 166 0.026
cell chemotaxis GO:0060326 112 0.026
cell development GO:0048468 328 0.026
divalent inorganic cation homeostasis GO:0072507 136 0.026
regulation of nucleoside metabolic process GO:0009118 209 0.026
reactive nitrogen species metabolic process GO:2001057 3 0.026
cellular calcium ion homeostasis GO:0006874 117 0.026
regulation of vesicle mediated transport GO:0060627 130 0.025
regulation of cellular response to growth factor stimulus GO:0090287 76 0.025
sulfur compound metabolic process GO:0006790 101 0.025
blood circulation GO:0008015 113 0.025
Mouse Rat
cell projection organization GO:0030030 252 0.025
chemotaxis GO:0006935 157 0.025
negative regulation of peptidase activity GO:0010466 91 0.025
regulation of wound healing GO:0061041 56 0.025
peptidyl tyrosine phosphorylation GO:0018108 170 0.025
protein catabolic process GO:0030163 325 0.025
neuromuscular junction development GO:0007528 3 0.025
response to increased oxygen levels GO:0036296 4 0.025
epithelium development GO:0060429 227 0.025
protein secretion GO:0009306 98 0.025
organonitrogen compound biosynthetic process GO:1901566 200 0.025
monocarboxylic acid biosynthetic process GO:0072330 67 0.024
dephosphorylation GO:0016311 209 0.024
organophosphate biosynthetic process GO:0090407 163 0.024
calcium ion homeostasis GO:0055074 122 0.024
inorganic ion transmembrane transport GO:0098660 231 0.024
negative regulation of proteolysis GO:0045861 132 0.024
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.024
positive regulation of cellular component movement GO:0051272 181 0.024
negative regulation of immune system process GO:0002683 136 0.024
regulation of cell activation GO:0050865 125 0.024
oxidation reduction process GO:0055114 396 0.024
negative regulation of protein maturation GO:1903318 142 0.024
nerve development GO:0021675 4 0.024
locomotory behavior GO:0007626 1 0.024
regulation of cytoplasmic transport GO:1903649 149 0.024
negative regulation of cell migration GO:0030336 102 0.024
regulation of stress activated mapk cascade GO:0032872 84 0.023
positive regulation of ras gtpase activity GO:0032320 117 0.023
response to metal ion GO:0010038 84 0.023
response to hypoxia GO:0001666 96 0.023
Human
regulation of small gtpase mediated signal transduction GO:0051056 156 0.023
negative regulation of cell cycle GO:0045786 193 0.023
negative regulation of transport GO:0051051 176 0.023
Rat
cellular macromolecular complex assembly GO:0034622 324 0.023
cellular response to transforming growth factor beta stimulus GO:0071560 94 0.023
regulation of endothelial cell migration GO:0010594 67 0.023
inorganic cation transmembrane transport GO:0098662 194 0.023
cellular macromolecule catabolic process GO:0044265 380 0.023
maintenance of location GO:0051235 112 0.023
tissue migration GO:0090130 119 0.023
regulation of gtp catabolic process GO:0033124 180 0.023
positive regulation of intracellular transport GO:0032388 104 0.023
leukocyte activation GO:0045321 164 0.023
cellular response to external stimulus GO:0071496 111 0.022
hemopoiesis GO:0030097 180 0.022
protein localization to membrane GO:0072657 160 0.022
regulation of cell cycle process GO:0010564 266 0.022
receptor internalization GO:0031623 43 0.022
blastoderm segmentation GO:0007350 2 0.022
cellular cation homeostasis GO:0030003 163 0.022
cellular metal ion homeostasis GO:0006875 146 0.022
negative regulation of cellular amine metabolic process GO:0033239 3 0.022
regulation of secretion GO:0051046 194 0.022
Rat
regulation of homeostatic process GO:0032844 121 0.022
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.022
tube development GO:0035295 125 0.022
jnk cascade GO:0007254 80 0.022
response to drug GO:0042493 81 0.022
immune system development GO:0002520 195 0.022
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.022
cellular response to lipid GO:0071396 127 0.022
rhythmic behavior GO:0007622 2 0.021
regulation of cytoskeleton organization GO:0051493 177 0.021
response to nutrient levels GO:0031667 81 0.021
negative regulation of protein processing GO:0010955 142 0.021
motor neuron axon guidance GO:0008045 2 0.021
cation transmembrane transport GO:0098655 238 0.021
receptor metabolic process GO:0043112 81 0.021
positive regulation of erk1 and erk2 cascade GO:0070374 75 0.021
organic hydroxy compound metabolic process GO:1901615 147 0.021
protein homooligomerization GO:0051260 100 0.021
positive regulation of organelle organization GO:0010638 195 0.021
positive regulation of vasoconstriction GO:0045907 3 0.021
Rat
cellular response to nitrogen compound GO:1901699 144 0.021
anion transport GO:0006820 161 0.021
cellular protein complex assembly GO:0043623 188 0.021
regulation of leukocyte migration GO:0002685 63 0.021
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.021
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.021
multi organism cellular process GO:0044764 156 0.021
atp metabolic process GO:0046034 176 0.021
endomembrane system organization GO:0010256 196 0.020
response to transforming growth factor beta GO:0071559 94 0.020
myeloid leukocyte migration GO:0097529 62 0.020
negative regulation of endopeptidase activity GO:0010951 84 0.020
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.020
muscle contraction GO:0006936 73 0.020
Rat
negative regulation of cell adhesion GO:0007162 64 0.020
regulation of lipid metabolic process GO:0019216 96 0.020
positive regulation of jnk cascade GO:0046330 52 0.020
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 125 0.020
protein targeting GO:0006605 187 0.020
hindbrain development GO:0030902 3 0.020
positive regulation of secretion by cell GO:1903532 108 0.020
positive regulation of epithelial cell proliferation GO:0050679 65 0.020
mitotic cell cycle process GO:1903047 286 0.020
regulation of synaptic plasticity GO:0048167 3 0.020
cell morphogenesis involved in differentiation GO:0000904 144 0.020
oocyte differentiation GO:0009994 2 0.020
positive regulation of defense response GO:0031349 87 0.019
establishment of protein localization to organelle GO:0072594 172 0.019
negative regulation of apoptotic signaling pathway GO:2001234 97 0.019
regulation of actin cytoskeleton organization GO:0032956 116 0.019
cell cell signaling GO:0007267 155 0.019
Rat
alcohol metabolic process GO:0006066 114 0.019
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.019
negative regulation of intracellular signal transduction GO:1902532 183 0.019
response to radiation GO:0009314 151 0.019
cellular response to dna damage stimulus GO:0006974 379 0.019
plasma membrane organization GO:0007009 115 0.019
muscle system process GO:0003012 81 0.019
Rat
regulation of binding GO:0051098 111 0.019
cellular response to oxygen levels GO:0071453 55 0.019
Human
carbohydrate metabolic process GO:0005975 207 0.019
actin filament organization GO:0007015 128 0.019
regulation of cell substrate adhesion GO:0010810 68 0.019
regulation of dna metabolic process GO:0051052 153 0.019
skeletal system development GO:0001501 79 0.019
cell division GO:0051301 168 0.019
mitotic cell cycle GO:0000278 326 0.019
regulation of neural precursor cell proliferation GO:2000177 4 0.018
cellular response to organonitrogen compound GO:0071417 124 0.018
growth GO:0040007 202 0.018
sequestering of calcium ion GO:0051208 17 0.018
regulation of protein complex assembly GO:0043254 147 0.018
icosanoid metabolic process GO:0006690 35 0.018
negative regulation of extrinsic apoptotic signaling pathway GO:2001237 52 0.018
cellular response to abiotic stimulus GO:0071214 117 0.018
ribonucleoside monophosphate metabolic process GO:0009161 187 0.018
positive regulation of acute inflammatory response GO:0002675 2 0.018
positive regulation of secretion GO:0051047 116 0.018
oocyte development GO:0048599 1 0.018
i kappab kinase nf kappab signaling GO:0007249 166 0.018
regulation of ras gtpase activity GO:0032318 128 0.018
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.018
nucleoside monophosphate metabolic process GO:0009123 191 0.018
cytosolic calcium ion homeostasis GO:0051480 89 0.018
regulation of protein maturation GO:1903317 150 0.018
positive regulation of endothelial cell migration GO:0010595 39 0.018
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 90 0.018
regulation of ion transmembrane transport GO:0034765 132 0.018
nucleocytoplasmic transport GO:0006913 176 0.018
regulation of cell morphogenesis GO:0022604 153 0.017
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.017
response to decreased oxygen levels GO:0036293 96 0.017
Human
protein ubiquitination GO:0016567 314 0.017
negative regulation of phosphorylation GO:0042326 174 0.017
sequestering of metal ion GO:0051238 24 0.017
negative regulation of reactive oxygen species metabolic process GO:2000378 11 0.017
glycerolipid metabolic process GO:0046486 107 0.017
purine nucleoside monophosphate metabolic process GO:0009126 186 0.017
ossification GO:0001503 121 0.017
morphogenesis of embryonic epithelium GO:0016331 4 0.017
regulation of membrane potential GO:0042391 95 0.017
regulation of endopeptidase activity GO:0052548 170 0.017
erk1 and erk2 cascade GO:0070371 104 0.017
response to extracellular stimulus GO:0009991 85 0.017
positive regulation of synaptic transmission GO:0050806 4 0.017
fatty acid derivative metabolic process GO:1901568 35 0.017
morphogenesis of an epithelium GO:0002009 60 0.017
posttranscriptional regulation of gene expression GO:0010608 213 0.017
reproductive process GO:0022414 106 0.017
leukocyte chemotaxis GO:0030595 76 0.017
regulation of transforming growth factor beta receptor signaling pathway GO:0017015 48 0.017
nucleoside phosphate biosynthetic process GO:1901293 109 0.017
regulation of protein targeting GO:1903533 91 0.017
reactive oxygen species biosynthetic process GO:1903409 4 0.017
central nervous system development GO:0007417 123 0.017
neuroblast proliferation GO:0007405 4 0.016
interspecies interaction between organisms GO:0044419 156 0.016
long chain fatty acid metabolic process GO:0001676 30 0.016
negative regulation of protein phosphorylation GO:0001933 140 0.016
myeloid cell differentiation GO:0030099 117 0.016
cell growth GO:0016049 160 0.016
nuclear transport GO:0051169 179 0.016
regulation of secretion by cell GO:1903530 177 0.016
Rat
negative regulation of cell differentiation GO:0045596 171 0.016
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.016
organic anion transport GO:0015711 103 0.016
positive regulation of proteolysis GO:0045862 142 0.016
response to tumor necrosis factor GO:0034612 76 0.016
response to lipopolysaccharide GO:0032496 70 0.016
embryo development GO:0009790 123 0.016
regulation of inflammatory response GO:0050727 46 0.016
regulation of endocytosis GO:0030100 72 0.016
cellular response to biotic stimulus GO:0071216 71 0.016
negative regulation of protein modification process GO:0031400 200 0.016
regulation of hemostasis GO:1900046 42 0.016
peptidyl serine phosphorylation GO:0018105 101 0.016
glycoprotein metabolic process GO:0009100 110 0.016
intrinsic apoptotic signaling pathway GO:0097193 127 0.016
regulation of myeloid leukocyte mediated immunity GO:0002886 4 0.016
regulation of protein catabolic process GO:0042176 155 0.016
mating GO:0007618 1 0.016
viral life cycle GO:0019058 132 0.016
regulation of erk1 and erk2 cascade GO:0070372 99 0.016
negative regulation of response to wounding GO:1903035 47 0.016
regulation of rho protein signal transduction GO:0035023 79 0.016
regulation of anatomical structure size GO:0090066 101 0.016
Rat
cellular response to organic cyclic compound GO:0071407 127 0.015
Zebrafish
peptidyl serine modification GO:0018209 106 0.015
hematopoietic or lymphoid organ development GO:0048534 186 0.015
regulation of leukocyte activation GO:0002694 115 0.015
histone modification GO:0016570 251 0.015
cranial nerve development GO:0021545 4 0.015
positive regulation of keratinocyte migration GO:0051549 4 0.015
endothelial cell proliferation GO:0001935 65 0.015
single organism carbohydrate metabolic process GO:0044723 193 0.015
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.015
sensory perception of pain GO:0019233 4 0.015
Rat
anterior posterior axis specification GO:0009948 2 0.015
tissue regeneration GO:0042246 3 0.015
circadian behavior GO:0048512 2 0.015
positive regulation of stress activated mapk cascade GO:0032874 60 0.015
regulation of actin filament based process GO:0032970 141 0.015
stress activated mapk cascade GO:0051403 93 0.015
nuclear import GO:0051170 106 0.015
regulation of calcium ion transport GO:0051924 79 0.015

PTGS1 disease predictions

Disease DO term ID Size Probability Func Analog Org
musculoskeletal system disease DOID:17 223 0.033
immune system disease DOID:2914 155 0.032
disease of metabolism DOID:0014667 295 0.026
connective tissue disease DOID:65 109 0.025
sensory system disease DOID:0050155 203 0.022
nervous system disease DOID:863 431 0.022
central nervous system disease DOID:331 186 0.021
inherited metabolic disorder DOID:655 242 0.018
hematopoietic system disease DOID:74 100 0.018
cancer DOID:162 167 0.017
disease of cellular proliferation DOID:14566 174 0.017
cardiovascular system disease DOID:1287 106 0.017
organ system cancer DOID:0050686 164 0.016