|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.718
|
|
|
|
negative regulation of transcription from rna polymerase ii promoter
|
GO:0000122 |
281 |
0.717
|
|
|
|
blood vessel development
|
GO:0001568 |
172 |
0.513
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.506
|
|
|
|
regulation of stress activated mapk cascade
|
GO:0032872 |
84 |
0.503
|
|
|
|
embryonic placenta development
|
GO:0001892 |
1 |
0.406
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.395
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
94 |
0.388
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.385
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.382
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.378
|
Human |
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.369
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.348
|
|
|
|
positive regulation of stress activated mapk cascade
|
GO:0032874 |
60 |
0.321
|
|
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.309
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.295
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.290
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.273
|
|
|
|
jnk cascade
|
GO:0007254 |
80 |
0.263
|
|
|
|
response to metal ion
|
GO:0010038 |
84 |
0.256
|
Zebrafish |
|
|
stress activated mapk cascade
|
GO:0051403 |
93 |
0.242
|
|
|
|
positive regulation of stress activated protein kinase signaling cascade
|
GO:0070304 |
61 |
0.234
|
|
|
|
endothelial cell migration
|
GO:0043542 |
86 |
0.226
|
|
|
|
negative regulation of interleukin 8 biosynthetic process
|
GO:0045415 |
3 |
0.225
|
|
|
|
rhythmic behavior
|
GO:0007622 |
2 |
0.225
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.222
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.215
|
|
|
|
vasculature development
|
GO:0001944 |
181 |
0.214
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.193
|
|
|
|
response to oxidative stress
|
GO:0006979 |
121 |
0.191
|
|
|
|
cellular response to metal ion
|
GO:0071248 |
43 |
0.183
|
|
|
|
positive regulation of jnk cascade
|
GO:0046330 |
52 |
0.182
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.171
|
|
|
|
response to inorganic substance
|
GO:0010035 |
127 |
0.170
|
Zebrafish |
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.168
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.167
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.166
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.166
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.165
|
|
|
|
mapk cascade
|
GO:0000165 |
288 |
0.144
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.144
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.143
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.143
|
|
|
|
regulation of erk1 and erk2 cascade
|
GO:0070372 |
99 |
0.141
|
|
|
|
leukocyte activation
|
GO:0045321 |
164 |
0.139
|
|
|
|
intrinsic apoptotic signaling pathway
|
GO:0097193 |
127 |
0.134
|
|
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.132
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.131
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.126
|
|
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.124
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.123
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.121
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.120
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
73 |
0.119
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.118
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.117
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.116
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.116
|
|
|
|
negative regulation of sequence specific dna binding transcription factor activity
|
GO:0043433 |
89 |
0.116
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.114
|
Mouse |
|
|
p38mapk cascade
|
GO:0038066 |
9 |
0.112
|
|
|
|
cytokine biosynthetic process
|
GO:0042089 |
37 |
0.111
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.107
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.103
|
Human |
|
|
cell activation
|
GO:0001775 |
213 |
0.103
|
|
|
|
regulation of angiogenesis
|
GO:0045765 |
92 |
0.101
|
|
|
|
regulation of myeloid cell differentiation
|
GO:0045637 |
81 |
0.099
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.099
|
Mouse |
|
|
membrane organization
|
GO:0061024 |
292 |
0.099
|
|
|
|
myeloid cell differentiation
|
GO:0030099 |
117 |
0.095
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
125 |
0.094
|
|
|
|
response to light stimulus
|
GO:0009416 |
87 |
0.091
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.090
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.089
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.089
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.087
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.087
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.086
|
|
|
|
hemopoiesis
|
GO:0030097 |
180 |
0.084
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.083
|
|
|
|
regulation of reactive oxygen species metabolic process
|
GO:2000377 |
41 |
0.083
|
Human |
|
|
response to reactive oxygen species
|
GO:0000302 |
61 |
0.081
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.080
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
170 |
0.080
|
|
|
|
cellular response to external stimulus
|
GO:0071496 |
111 |
0.078
|
Human |
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.076
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.076
|
|
|
|
positive regulation of cellular component movement
|
GO:0051272 |
181 |
0.076
|
|
|
|
neuron projection regeneration
|
GO:0031102 |
1 |
0.074
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.074
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.072
|
|
|
|
response to wounding
|
GO:0009611 |
168 |
0.071
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.070
|
|
|
|
erk1 and erk2 cascade
|
GO:0070371 |
104 |
0.065
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.065
|
|
|
|
activation of mapkkk activity
|
GO:0000185 |
7 |
0.064
|
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
117 |
0.063
|
Human |
|
|
regeneration
|
GO:0031099 |
4 |
0.063
|
|
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.063
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.063
|
|
|
|
cellular response to oxidative stress
|
GO:0034599 |
85 |
0.062
|
|
|
|
negative regulation of immune system process
|
GO:0002683 |
136 |
0.061
|
|
|
|
response to camp
|
GO:0051591 |
25 |
0.061
|
|
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.060
|
|
|
|
regulation of response to wounding
|
GO:1903034 |
101 |
0.059
|
|
|
|
chordate embryonic development
|
GO:0043009 |
34 |
0.059
|
Zebrafish |
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.058
|
|
|
|
post embryonic hemopoiesis
|
GO:0035166 |
1 |
0.057
|
|
|
|
embryo development
|
GO:0009790 |
123 |
0.056
|
Zebrafish |
|
|
cellular response to inorganic substance
|
GO:0071241 |
45 |
0.055
|
|
|
|
cellular response to nitrogen compound
|
GO:1901699 |
144 |
0.055
|
|
|
|
viral life cycle
|
GO:0019058 |
132 |
0.055
|
|
|
|
positive regulation of p38mapk cascade
|
GO:1900745 |
8 |
0.055
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.055
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.053
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
116 |
0.053
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.053
|
Mouse |
|
|
cytokine production
|
GO:0001816 |
247 |
0.051
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
166 |
0.051
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.050
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.050
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.050
|
|
|
|
wound healing
|
GO:0042060 |
115 |
0.050
|
|
|
|
negative regulation of protein processing
|
GO:0010955 |
142 |
0.049
|
|
|
|
response to calcium ion
|
GO:0051592 |
46 |
0.049
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.049
|
|
|
|
hemoglobin metabolic process
|
GO:0020027 |
3 |
0.048
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.048
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.048
|
|
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.048
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.048
|
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.047
|
|
|
|
negative regulation of cellular amine metabolic process
|
GO:0033239 |
3 |
0.046
|
|
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.046
|
|
|
|
regulation of system process
|
GO:0044057 |
101 |
0.045
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.045
|
|
|
|
response to extracellular stimulus
|
GO:0009991 |
85 |
0.045
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.045
|
|
|
|
reactive nitrogen species metabolic process
|
GO:2001057 |
3 |
0.045
|
|
|
|
cellular response to hydrogen peroxide
|
GO:0070301 |
37 |
0.044
|
|
|
|
compound eye development
|
GO:0048749 |
1 |
0.044
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.044
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.043
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.043
|
|
|
|
positive regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043280 |
69 |
0.043
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.043
|
|
|
|
negative regulation of protein maturation
|
GO:1903318 |
142 |
0.043
|
|
|
|
regulation of defense response
|
GO:0031347 |
154 |
0.043
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.042
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.042
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.041
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.041
|
|
|
|
response to endoplasmic reticulum stress
|
GO:0034976 |
49 |
0.041
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.041
|
Zebrafish |
|
|
reproductive system development
|
GO:0061458 |
56 |
0.040
|
|
|
|
immune system development
|
GO:0002520 |
195 |
0.039
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.039
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.039
|
|
|
|
negative regulation of response to external stimulus
|
GO:0032102 |
83 |
0.039
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.039
|
|
|
|
peptidyl lysine modification
|
GO:0018205 |
144 |
0.039
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.038
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.038
|
|
|
|
regulation of vasculature development
|
GO:1901342 |
97 |
0.038
|
|
|
|
response to cytokine
|
GO:0034097 |
232 |
0.038
|
|
|
|
protein processing
|
GO:0016485 |
226 |
0.037
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.037
|
|
|
|
chondroblast differentiation
|
GO:0060591 |
2 |
0.037
|
|
|
|
positive regulation of transcription from rna polymerase ii promoter in response to stress
|
GO:0036003 |
9 |
0.037
|
|
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.037
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.037
|
Mouse |
|
|
positive regulation of hemoglobin biosynthetic process
|
GO:0046985 |
1 |
0.037
|
|
|
|
circulatory system process
|
GO:0003013 |
113 |
0.036
|
|
|
|
positive regulation of angiogenesis
|
GO:0045766 |
51 |
0.036
|
|
|
|
negative regulation of response to wounding
|
GO:1903035 |
47 |
0.036
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.036
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.036
|
|
|
|
placenta development
|
GO:0001890 |
10 |
0.035
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.035
|
|
|
|
sex determination
|
GO:0007530 |
3 |
0.035
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.035
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.034
|
|
|
|
negative regulation of erythrocyte differentiation
|
GO:0045647 |
3 |
0.034
|
|
|
|
muscle cell differentiation
|
GO:0042692 |
63 |
0.034
|
|
|
|
ossification
|
GO:0001503 |
121 |
0.034
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
119 |
0.034
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.033
|
Zebrafish |
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.033
|
|
|
|
lipid biosynthetic process
|
GO:0008610 |
177 |
0.033
|
|
|
|
positive regulation of cell adhesion
|
GO:0045785 |
84 |
0.033
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.033
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.032
|
|
|
|
regulation of protein processing
|
GO:0070613 |
150 |
0.032
|
|
|
|
carbohydrate metabolic process
|
GO:0005975 |
207 |
0.032
|
|
|
|
mitochondrion organization
|
GO:0007005 |
156 |
0.032
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.032
|
|
|
|
regulation of cell cell adhesion
|
GO:0022407 |
57 |
0.032
|
|
|
|
rna processing
|
GO:0006396 |
255 |
0.031
|
|
|
|
negative regulation of angiogenesis
|
GO:0016525 |
39 |
0.031
|
|
|
|
cellular response to cytokine stimulus
|
GO:0071345 |
181 |
0.031
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
26 |
0.031
|
|
|
|
tissue migration
|
GO:0090130 |
119 |
0.031
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.030
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.030
|
|
|
|
response to virus
|
GO:0009615 |
126 |
0.030
|
|
|
|
inflammatory response
|
GO:0006954 |
79 |
0.030
|
|
|
|
single organism membrane organization
|
GO:0044802 |
268 |
0.030
|
|
|
|
regulation of mrna processing
|
GO:0050684 |
48 |
0.030
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
303 |
0.030
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.030
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.030
|
Mouse |
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
182 |
0.030
|
|
|
|
neurological system process
|
GO:0050877 |
163 |
0.029
|
|
|
|
cellular hyperosmotic response
|
GO:0071474 |
4 |
0.029
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.029
|
|
|
|
circadian behavior
|
GO:0048512 |
2 |
0.028
|
|
|
|
response to salt stress
|
GO:0009651 |
3 |
0.028
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.028
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.028
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.028
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.028
|
|
|
|
protein acetylation
|
GO:0006473 |
116 |
0.027
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.027
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.027
|
|
|
|
negative regulation of cytokine production
|
GO:0001818 |
82 |
0.027
|
|
|
|
regulation of cyclin dependent protein serine threonine kinase activity
|
GO:0000079 |
36 |
0.027
|
|
|
|
negative regulation of chemokine production
|
GO:0032682 |
9 |
0.027
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.026
|
|
|
|
immune effector process
|
GO:0002252 |
159 |
0.026
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
177 |
0.026
|
|
|
|
organonitrogen compound biosynthetic process
|
GO:1901566 |
200 |
0.026
|
|
|
|
negative regulation of dna metabolic process
|
GO:0051053 |
57 |
0.026
|
|
|
|
behavior
|
GO:0007610 |
112 |
0.026
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.026
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.025
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
124 |
0.025
|
Mouse |
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.025
|
|
|
|
response to hexose
|
GO:0009746 |
20 |
0.025
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.025
|
|
|
|
translation
|
GO:0006412 |
132 |
0.025
|
|
|
|
blood circulation
|
GO:0008015 |
113 |
0.025
|
|
|
|
endocytosis
|
GO:0006897 |
159 |
0.025
|
|
|
|
reproductive process
|
GO:0022414 |
106 |
0.025
|
|
|
|
regulation of cyclic nucleotide biosynthetic process
|
GO:0030802 |
49 |
0.025
|
|
|
|
internal protein amino acid acetylation
|
GO:0006475 |
101 |
0.025
|
|
|
|
negative regulation of cell motility
|
GO:2000146 |
104 |
0.025
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.025
|
|
|
|
monocarboxylic acid metabolic process
|
GO:0032787 |
185 |
0.025
|
|
|
|
engulfment of apoptotic cell
|
GO:0043652 |
2 |
0.025
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
101 |
0.024
|
|
|
|
osteoblast differentiation
|
GO:0001649 |
92 |
0.024
|
|
|
|
response to axon injury
|
GO:0048678 |
1 |
0.024
|
|
|
|
reactive oxygen species metabolic process
|
GO:0072593 |
75 |
0.024
|
Human |
|
|
negative regulation of defense response
|
GO:0031348 |
47 |
0.024
|
|
|
|
regulation of ossification
|
GO:0030278 |
58 |
0.024
|
|
|
|
developmental programmed cell death
|
GO:0010623 |
3 |
0.024
|
|
|
|
negative regulation of cellular amino acid metabolic process
|
GO:0045763 |
2 |
0.024
|
|
|
|
positive regulation of immune response
|
GO:0050778 |
159 |
0.023
|
|
|
|
erythrocyte differentiation
|
GO:0030218 |
28 |
0.023
|
|
|
|
single organism cell adhesion
|
GO:0098602 |
179 |
0.023
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.023
|
|
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.023
|
|
|
|
cellular response to reactive oxygen species
|
GO:0034614 |
50 |
0.023
|
|
|
|
system process
|
GO:0003008 |
349 |
0.023
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.023
|
|
|
|
response to radiation
|
GO:0009314 |
151 |
0.023
|
Human |
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
127 |
0.023
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.023
|
Mouse |
|
|
sleep
|
GO:0030431 |
2 |
0.023
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
148 |
0.023
|
|
|
|
monosaccharide metabolic process
|
GO:0005996 |
74 |
0.022
|
|
|
|
chromatin organization
|
GO:0006325 |
351 |
0.022
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
0.022
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.022
|
|
|
|
negative regulation of chromosome organization
|
GO:2001251 |
48 |
0.022
|
|
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.022
|
|
|
|
regulation of vasculogenesis
|
GO:2001212 |
3 |
0.022
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
92 |
0.022
|
|
|
|
neural tube formation
|
GO:0001841 |
3 |
0.022
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.022
|
|
|
|
multi organism cellular process
|
GO:0044764 |
156 |
0.022
|
|
|
|
response to uv
|
GO:0009411 |
73 |
0.022
|
|
|
|
regulation of stress activated protein kinase signaling cascade
|
GO:0070302 |
85 |
0.022
|
|
|
|
positive regulation of cell size
|
GO:0045793 |
3 |
0.022
|
|
|
|
growth
|
GO:0040007 |
202 |
0.021
|
|
|
|
regulation of leukocyte differentiation
|
GO:1902105 |
61 |
0.021
|
|
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.021
|
|
|
|
regulation of rho gtpase activity
|
GO:0032319 |
66 |
0.021
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.021
|
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.021
|
|
|
|
atrioventricular valve morphogenesis
|
GO:0003181 |
2 |
0.021
|
|
|
|
developmental process involved in reproduction
|
GO:0003006 |
66 |
0.021
|
|
|
|
regulation of nucleotide biosynthetic process
|
GO:0030808 |
50 |
0.020
|
|
|
|
rna interference
|
GO:0016246 |
4 |
0.020
|
|
|
|
regulation of homeostatic process
|
GO:0032844 |
121 |
0.020
|
|
|
|
cellular chemical homeostasis
|
GO:0055082 |
180 |
0.020
|
|
|
|
negative regulation of endopeptidase activity
|
GO:0010951 |
84 |
0.020
|
|
|
|
purine containing compound biosynthetic process
|
GO:0072522 |
88 |
0.020
|
|
|
|
positive regulation of endopeptidase activity
|
GO:0010950 |
84 |
0.020
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.020
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.020
|
|
|
|
cellular response to ionizing radiation
|
GO:0071479 |
32 |
0.020
|
Human |
|
|
cyclic nucleotide biosynthetic process
|
GO:0009190 |
61 |
0.020
|
|
|
|
regulation of translation
|
GO:0006417 |
89 |
0.019
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.019
|
|
|
|
positive regulation of reactive oxygen species metabolic process
|
GO:2000379 |
24 |
0.019
|
Human |
|
|
epithelial cell migration
|
GO:0010631 |
119 |
0.019
|
|
|
|
regulation of dna metabolic process
|
GO:0051052 |
153 |
0.019
|
|
|
|
activation of protein kinase activity
|
GO:0032147 |
90 |
0.019
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
141 |
0.019
|
|
|
|
homeostasis of number of cells
|
GO:0048872 |
40 |
0.019
|
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
166 |
0.019
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.019
|
|
|
|
osteoblast proliferation
|
GO:0033687 |
8 |
0.019
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
150 |
0.019
|
|
|
|
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains
|
GO:0002460 |
40 |
0.019
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.019
|
|
|
|
negative regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043154 |
46 |
0.019
|
|
|
|
negative regulation of cell cycle process
|
GO:0010948 |
121 |
0.019
|
|
|
|
regulation of inflammatory response
|
GO:0050727 |
46 |
0.019
|
|
|
|
stress fiber assembly
|
GO:0043149 |
40 |
0.019
|
|
|
|
nucleotide biosynthetic process
|
GO:0009165 |
109 |
0.019
|
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.019
|
|
|
|
positive regulation of actin filament bundle assembly
|
GO:0032233 |
25 |
0.019
|
|
|
|
fibroblast proliferation
|
GO:0048144 |
33 |
0.019
|
|
|
|
negative regulation of chemokine c x c motif ligand 2 production
|
GO:2000342 |
1 |
0.019
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
172 |
0.019
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.019
|
|
|
|
negative regulation of cysteine type endopeptidase activity
|
GO:2000117 |
48 |
0.019
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
180 |
0.019
|
|
|
|
positive regulation of camp biosynthetic process
|
GO:0030819 |
35 |
0.019
|
|
|
|
response to unfolded protein
|
GO:0006986 |
24 |
0.019
|
|
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
94 |
0.018
|
|
|
|
innate immune response
|
GO:0045087 |
178 |
0.018
|
|
|
|
purine ribonucleotide biosynthetic process
|
GO:0009152 |
79 |
0.018
|
|
|
|
divalent metal ion transport
|
GO:0070838 |
152 |
0.018
|
|
|
|
regulation of leukocyte activation
|
GO:0002694 |
115 |
0.018
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.018
|
|
|
|
regulation of transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0090092 |
90 |
0.018
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
125 |
0.018
|
|
|
|
single organism carbohydrate metabolic process
|
GO:0044723 |
193 |
0.018
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.018
|
|
|
|
nerve development
|
GO:0021675 |
4 |
0.018
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
130 |
0.018
|
|
|
|
cell growth
|
GO:0016049 |
160 |
0.018
|
|
|
|
angiogenesis
|
GO:0001525 |
147 |
0.018
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.018
|
|
|
|
positive regulation of protein catabolic process
|
GO:0045732 |
75 |
0.018
|
|
|
|
rhythmic process
|
GO:0048511 |
31 |
0.018
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.018
|
|
|
|
cellular response to mechanical stimulus
|
GO:0071260 |
39 |
0.017
|
Human |
|
|
response to osmotic stress
|
GO:0006970 |
17 |
0.017
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.017
|
|
|
|
cyclic purine nucleotide metabolic process
|
GO:0052652 |
60 |
0.017
|
|
|
|
negative regulation of blood vessel morphogenesis
|
GO:2000181 |
41 |
0.017
|
|
|
|
dna conformation change
|
GO:0071103 |
113 |
0.017
|
|
|
|
negative regulation of myeloid cell differentiation
|
GO:0045638 |
42 |
0.017
|
|
|
|
ribonucleotide biosynthetic process
|
GO:0009260 |
81 |
0.017
|
|
|
|
chromatin modification
|
GO:0016568 |
298 |
0.017
|
|
|
|
negative regulation of cd4 positive alpha beta t cell activation
|
GO:2000515 |
1 |
0.017
|
|
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.017
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.017
|
|
|
|
smad protein signal transduction
|
GO:0060395 |
10 |
0.017
|
|
|
|
cellular carbohydrate metabolic process
|
GO:0044262 |
84 |
0.017
|
|
|
|
purine nucleotide biosynthetic process
|
GO:0006164 |
84 |
0.017
|
|
|
|
regulation of secretion
|
GO:0051046 |
194 |
0.017
|
|
|
|
microtubule based process
|
GO:0007017 |
210 |
0.017
|
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
158 |
0.017
|
|
|
|
regulation of tube size
|
GO:0035150 |
18 |
0.017
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.017
|
|
|
|
rna stabilization
|
GO:0043489 |
18 |
0.017
|
|
|
|
optic nerve development
|
GO:0021554 |
2 |
0.017
|
|
|
|
response to mechanical stimulus
|
GO:0009612 |
51 |
0.017
|
Human |
|
|
chromatin assembly or disassembly
|
GO:0006333 |
78 |
0.016
|
|
|
|
axon regeneration
|
GO:0031103 |
1 |
0.016
|
|
|
|
regulation of cell cycle phase transition
|
GO:1901987 |
126 |
0.016
|
|
|
|
actin filament bundle assembly
|
GO:0051017 |
54 |
0.016
|
|
|
|
mitochondrial transport
|
GO:0006839 |
60 |
0.016
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.016
|
|
|
|
single organism reproductive process
|
GO:0044702 |
98 |
0.016
|
|
|
|
peptidyl lysine acetylation
|
GO:0018394 |
101 |
0.016
|
|
|
|
positive regulation of cyclic nucleotide biosynthetic process
|
GO:0030804 |
38 |
0.016
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.016
|
|
|
|
cytokine metabolic process
|
GO:0042107 |
38 |
0.016
|
|
|
|
response to cycloheximide
|
GO:0046898 |
1 |
0.016
|
|
|
|
nucleoside phosphate biosynthetic process
|
GO:1901293 |
109 |
0.016
|
|
|
|
regulation of cytokine biosynthetic process
|
GO:0042035 |
35 |
0.016
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.016
|
|
|
|
metal ion transport
|
GO:0030001 |
272 |
0.016
|
|
|
|
chromatin assembly
|
GO:0031497 |
61 |
0.016
|
|
|
|
positive regulation of erk1 and erk2 cascade
|
GO:0070374 |
75 |
0.016
|
|
|
|
regulation of ras gtpase activity
|
GO:0032318 |
128 |
0.016
|
|
|
|
hyperosmotic response
|
GO:0006972 |
4 |
0.016
|
|
|
|
lymphocyte activation
|
GO:0046649 |
133 |
0.016
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.016
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
207 |
0.015
|
|
|
|
respiratory gaseous exchange
|
GO:0007585 |
3 |
0.015
|
|
|
|
epithelium migration
|
GO:0090132 |
119 |
0.015
|
|
|
|
cell substrate adhesion
|
GO:0031589 |
132 |
0.015
|
|
|
|
leukocyte chemotaxis
|
GO:0030595 |
76 |
0.015
|
|
|
|
cellular response to peptide
|
GO:1901653 |
59 |
0.015
|
|
|
|
head development
|
GO:0060322 |
108 |
0.015
|
|
|
|
camp biosynthetic process
|
GO:0006171 |
47 |
0.015
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
127 |
0.015
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.015
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.015
|
|
|
|
positive regulation of mrna 3 end processing
|
GO:0031442 |
12 |
0.015
|
|
|
|
cellular homeostasis
|
GO:0019725 |
196 |
0.015
|
|
|
|
extrinsic apoptotic signaling pathway via death domain receptors
|
GO:0008625 |
42 |
0.015
|
|
|
|
regulation of reactive oxygen species biosynthetic process
|
GO:1903426 |
3 |
0.015
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.015
|
|
|
|
cranial nerve development
|
GO:0021545 |
4 |
0.014
|
|
|
|
interspecies interaction between organisms
|
GO:0044419 |
156 |
0.014
|
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.014
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
116 |
0.014
|
|
|
|
positive regulation of peptidase activity
|
GO:0010952 |
88 |
0.014
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.014
|
|
|
|
rna 3 end processing
|
GO:0031123 |
35 |
0.014
|
|
|
|
cellular response to glucocorticoid stimulus
|
GO:0071385 |
4 |
0.014
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.014
|
|
|
|
divalent inorganic cation transport
|
GO:0072511 |
158 |
0.014
|
|
|
|
chemokine c x c motif ligand 2 production
|
GO:0072567 |
3 |
0.014
|
|
|
|
actomyosin structure organization
|
GO:0031032 |
59 |
0.014
|
|
|
|
response to transforming growth factor beta
|
GO:0071559 |
94 |
0.014
|
|
|
|
primary neural tube formation
|
GO:0014020 |
3 |
0.014
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
123 |
0.014
|
|
|
|
activation of immune response
|
GO:0002253 |
114 |
0.014
|
|
|
|
antimicrobial humoral response
|
GO:0019730 |
26 |
0.014
|
|
|
|
regulation of i kappab kinase nf kappab signaling
|
GO:0043122 |
162 |
0.014
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
140 |
0.014
|
|
|
|
calcium ion transport
|
GO:0006816 |
147 |
0.014
|
|
|
|
negative regulation of cellular carbohydrate metabolic process
|
GO:0010677 |
14 |
0.014
|
|
|
|
mrna catabolic process
|
GO:0006402 |
56 |
0.013
|
|
|
|
neural tube closure
|
GO:0001843 |
3 |
0.013
|
|
|
|
leukocyte differentiation
|
GO:0002521 |
98 |
0.013
|
|
|
|
organophosphate biosynthetic process
|
GO:0090407 |
163 |
0.013
|
|
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
186 |
0.013
|
|
|
|
regulation of metal ion transport
|
GO:0010959 |
120 |
0.013
|
|
|
|
embryonic epithelial tube formation
|
GO:0001838 |
4 |
0.013
|
|
|
|
cell type specific apoptotic process
|
GO:0097285 |
125 |
0.013
|
|
|
|
negative regulation of interleukin 8 production
|
GO:0032717 |
12 |
0.013
|
|
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
118 |
0.013
|
|
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
117 |
0.013
|
|
|
|
protein acylation
|
GO:0043543 |
138 |
0.013
|
|
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
205 |
0.013
|
|
|
|
regulation of g protein coupled receptor protein signaling pathway
|
GO:0008277 |
35 |
0.013
|
|
|
|
reproductive structure development
|
GO:0048608 |
55 |
0.013
|
|
|
|
positive regulation of nuclear transcribed mrna poly a tail shortening
|
GO:0060213 |
8 |
0.013
|
|
|
|
trophectodermal cell differentiation
|
GO:0001829 |
3 |
0.013
|
|
|
|
striated muscle tissue development
|
GO:0014706 |
59 |
0.013
|
|
|
|
collateral sprouting
|
GO:0048668 |
2 |
0.013
|
|
|
|
regulation of small gtpase mediated signal transduction
|
GO:0051056 |
156 |
0.013
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.013
|
|
|
|
regulation of peptidyl lysine acetylation
|
GO:2000756 |
22 |
0.013
|
|
|
|
negative regulation of plasminogen activation
|
GO:0010757 |
4 |
0.013
|
|
|
|
hematopoietic stem cell differentiation
|
GO:0060218 |
4 |
0.013
|
|
|
|
circadian rhythm
|
GO:0007623 |
21 |
0.013
|
|
|
|
brain development
|
GO:0007420 |
97 |
0.013
|
|
|
|
negative regulation of organelle organization
|
GO:0010639 |
126 |
0.013
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
124 |
0.013
|
|
|
|
midbrain development
|
GO:0030901 |
45 |
0.013
|
|
|
|
positive regulation of map kinase activity
|
GO:0043406 |
80 |
0.013
|
Mouse |
|
|
mrna processing
|
GO:0006397 |
133 |
0.013
|
|
|
|
blastocyst formation
|
GO:0001825 |
3 |
0.013
|
|
|
|
regulation of cyclic nucleotide metabolic process
|
GO:0030799 |
63 |
0.013
|
|
|
|
regulation of interleukin 8 production
|
GO:0032677 |
49 |
0.013
|
|
|
|
multi organism reproductive process
|
GO:0044703 |
54 |
0.012
|
|
|
|
lipid localization
|
GO:0010876 |
106 |
0.012
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
166 |
0.012
|
|
|
|
response to carbohydrate
|
GO:0009743 |
21 |
0.012
|
|
|
|
cd4 positive alpha beta t cell differentiation
|
GO:0043367 |
4 |
0.012
|
|
|
|
bone mineralization
|
GO:0030282 |
34 |
0.012
|
|
|
|
erythrocyte homeostasis
|
GO:0034101 |
31 |
0.012
|
|
|
|
embryonic organ development
|
GO:0048568 |
36 |
0.012
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
135 |
0.012
|
|
|
|
negative regulation of mitotic cell cycle
|
GO:0045930 |
102 |
0.012
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.012
|
|
|
|
peripheral nervous system development
|
GO:0007422 |
2 |
0.012
|
|
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
0.012
|
|
|
|
response to corticosteroid
|
GO:0031960 |
15 |
0.012
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.012
|
|
|
|
dna packaging
|
GO:0006323 |
77 |
0.012
|
|
|
|
cell cycle checkpoint
|
GO:0000075 |
117 |
0.012
|
|
|
|
skeletal system development
|
GO:0001501 |
79 |
0.012
|
|
|
|
regulation of antimicrobial humoral response
|
GO:0002759 |
1 |
0.012
|
|
|
|
posttranscriptional gene silencing by rna
|
GO:0035194 |
25 |
0.012
|
|
|
|
negative regulation of proteolysis
|
GO:0045861 |
132 |
0.012
|
|
|
|
regulation of protein secretion
|
GO:0050708 |
86 |
0.012
|
|
|
|
negative regulation of cellular component movement
|
GO:0051271 |
106 |
0.012
|
|
|
|
actin filament bundle organization
|
GO:0061572 |
54 |
0.012
|
|
|
|
cranial nerve morphogenesis
|
GO:0021602 |
1 |
0.012
|
|
|
|
blastocyst development
|
GO:0001824 |
3 |
0.012
|
|
|
|
multicellular organismal metabolic process
|
GO:0044236 |
34 |
0.012
|
|
|
|
neuron development
|
GO:0048666 |
113 |
0.012
|
|
|
|
regulation of neural precursor cell proliferation
|
GO:2000177 |
4 |
0.011
|
|
