Homo sapiens

3 known processes

RXFP2

relaxin/insulin-like family peptide receptor 2

(Aliases: GREAT,LGR8.1,LGR8,INSL3R,GPR106,RXFPR2)

RXFP2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
detection of chemical stimulus involved in sensory perception of smell GO:0050911 2 0.075
post embryonic development GO:0009791 2 0.060
cellular ketone metabolic process GO:0042180 80 0.059
regulation of cellular ketone metabolic process GO:0010565 50 0.054
cellular amine metabolic process GO:0044106 41 0.048
cellular amino acid metabolic process GO:0006520 116 0.048
regulation of cellular amine metabolic process GO:0033238 11 0.048
amine metabolic process GO:0009308 44 0.046
regulation of cellular amino acid metabolic process GO:0006521 6 0.042
positive regulation of cellular amine metabolic process GO:0033240 7 0.037
multicellular organismal aging GO:0010259 3 0.035
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.034
determination of adult lifespan GO:0008340 2 0.034
system process GO:0003008 349 0.029
negative regulation of protein metabolic process GO:0051248 391 0.028
female gamete generation GO:0007292 2 0.028
Rat
negative regulation of cellular protein metabolic process GO:0032269 353 0.027
oogenesis GO:0048477 2 0.026
Rat
negative regulation of catalytic activity GO:0043086 335 0.025
locomotory behavior GO:0007626 1 0.025
ras protein signal transduction GO:0007265 73 0.024
regeneration GO:0031099 4 0.024
lipid metabolic process GO:0006629 381 0.023
defense response GO:0006952 315 0.023
regulation of transferase activity GO:0051338 355 0.023
immune response GO:0006955 307 0.023
purine ribonucleoside metabolic process GO:0046128 437 0.022
cellular macromolecule catabolic process GO:0044265 380 0.022
biological adhesion GO:0022610 331 0.022
innate immune response GO:0045087 178 0.022
cellular lipid metabolic process GO:0044255 303 0.021
positive regulation of transport GO:0051050 336 0.021
chemical homeostasis GO:0048878 306 0.021
positive regulation of phosphorylation GO:0042327 394 0.021
protein catabolic process GO:0030163 325 0.021
segmentation GO:0035282 4 0.021
organophosphate catabolic process GO:0046434 430 0.021
response to abiotic stimulus GO:0009628 336 0.021
small gtpase mediated signal transduction GO:0007264 78 0.021
positive regulation of protein phosphorylation GO:0001934 313 0.020
positive regulation of hydrolase activity GO:0051345 331 0.020
positive regulation of catabolic process GO:0009896 310 0.020
positive regulation of cellular catabolic process GO:0031331 284 0.020
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.020
regulation of protein localization GO:0032880 296 0.020
nucleoside triphosphate metabolic process GO:0009141 422 0.020
regulation of kinase activity GO:0043549 314 0.020
regulation of cell cycle GO:0051726 393 0.020
detection of chemical stimulus involved in sensory perception GO:0050907 33 0.019
g protein coupled receptor signaling pathway GO:0007186 207 0.019
Human Mouse Rat
negative regulation of phosphate metabolic process GO:0045936 267 0.019
ribonucleoside catabolic process GO:0042454 406 0.019
regulation of protein kinase activity GO:0045859 289 0.019
ribonucleoside triphosphate metabolic process GO:0009199 412 0.019
regulation of nucleotide metabolic process GO:0006140 269 0.019
Rat
purine nucleoside triphosphate metabolic process GO:0009144 412 0.019
negative regulation of phosphorus metabolic process GO:0010563 267 0.018
ribonucleoside triphosphate catabolic process GO:0009203 391 0.018
neuromuscular junction development GO:0007528 3 0.018
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.018
regulation of proteolysis GO:0030162 293 0.018
positive regulation of cellular component organization GO:0051130 376 0.018
protein maturation GO:0051604 233 0.018
spermatid differentiation GO:0048515 4 0.018
positive regulation of immune system process GO:0002684 283 0.018
regulation of cytokine production GO:0001817 232 0.018
actin filament based process GO:0030029 224 0.018
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.018
purine containing compound catabolic process GO:0072523 411 0.018
cellular response to dna damage stimulus GO:0006974 379 0.018
cellular protein catabolic process GO:0044257 261 0.018
negative regulation of cellular amine metabolic process GO:0033239 3 0.017
cytokine production GO:0001816 247 0.017
ribonucleotide catabolic process GO:0009261 405 0.017
single organism membrane organization GO:0044802 268 0.017
memory GO:0007613 3 0.017
protein ubiquitination GO:0016567 314 0.017
regulation of cellular response to stress GO:0080135 244 0.017
mapk cascade GO:0000165 288 0.017
response to oxygen containing compound GO:1901700 369 0.017
nucleotide catabolic process GO:0009166 408 0.017
nucleoside triphosphate catabolic process GO:0009143 394 0.017
carbohydrate derivative biosynthetic process GO:1901137 207 0.017
Rat
neurological system process GO:0050877 163 0.017
single organism cellular localization GO:1902580 332 0.017
cytoplasmic transport GO:0016482 379 0.017
signal transduction by phosphorylation GO:0023014 297 0.017
purine nucleoside catabolic process GO:0006152 398 0.017
positive regulation of cell death GO:0010942 263 0.017
cell adhesion GO:0007155 325 0.017
glycosyl compound catabolic process GO:1901658 413 0.017
maintenance of location GO:0051235 112 0.016
vesicle mediated transport GO:0016192 371 0.016
regulation of purine nucleotide metabolic process GO:1900542 264 0.016
Rat
purine nucleotide catabolic process GO:0006195 405 0.016
response to other organism GO:0051707 261 0.016
response to external biotic stimulus GO:0043207 261 0.016
ion homeostasis GO:0050801 230 0.016
purine nucleoside triphosphate catabolic process GO:0009146 392 0.016
response to biotic stimulus GO:0009607 276 0.016
negative regulation of hydrolase activity GO:0051346 182 0.016
positive regulation of transferase activity GO:0051347 227 0.016
protein processing GO:0016485 226 0.016
cellular macromolecular complex assembly GO:0034622 324 0.016
purine ribonucleotide catabolic process GO:0009154 404 0.016
apoptotic signaling pathway GO:0097190 268 0.016
nucleoside catabolic process GO:0009164 408 0.016
regulation of cell cycle process GO:0010564 266 0.016
negative regulation of multicellular organismal process GO:0051241 317 0.016
spermatid development GO:0007286 4 0.016
response to fungus GO:0009620 4 0.016
nucleoside phosphate catabolic process GO:1901292 412 0.016
regulation of response to external stimulus GO:0032101 222 0.016
oocyte differentiation GO:0009994 2 0.016
Rat
regulation of cellular component movement GO:0051270 334 0.016
cellular component morphogenesis GO:0032989 314 0.016
blastoderm segmentation GO:0007350 2 0.015
cell morphogenesis GO:0000902 296 0.015
oocyte development GO:0048599 1 0.015
Rat
anterior posterior axis specification GO:0009948 2 0.015
negative regulation of cell death GO:0060548 345 0.015
Rat
dephosphorylation GO:0016311 209 0.015
regulation of establishment of protein localization GO:0070201 242 0.015
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.015
negative regulation of cellular component organization GO:0051129 235 0.015
morphogenesis of embryonic epithelium GO:0016331 4 0.015
regulation of immune response GO:0050776 201 0.015
positive regulation of apoptotic process GO:0043065 246 0.015
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.015
Rat
mitotic cell cycle GO:0000278 326 0.015
lipid biosynthetic process GO:0008610 177 0.015
regulation of secretion GO:0051046 194 0.015
membrane organization GO:0061024 292 0.015
regulation of protein serine threonine kinase activity GO:0071900 179 0.015
regulation of anatomical structure morphogenesis GO:0022603 286 0.015
regulation of protein transport GO:0051223 213 0.015
rho protein signal transduction GO:0007266 26 0.015
mitotic cell cycle process GO:1903047 286 0.015
regulation of secretion by cell GO:1903530 177 0.015
sensory perception of smell GO:0007608 2 0.014
release of cytoplasmic sequestered nf kappab GO:0008588 4 0.014
positive regulation of cell proliferation GO:0008284 301 0.014
reactive oxygen species biosynthetic process GO:1903409 4 0.014
intracellular protein transport GO:0006886 270 0.014
positive regulation of kinase activity GO:0033674 204 0.014
negative regulation of protein modification process GO:0031400 200 0.014
cellular homeostasis GO:0019725 196 0.014
anterior posterior axis specification embryo GO:0008595 2 0.014
negative regulation of programmed cell death GO:0043069 321 0.014
Rat
reactive nitrogen species metabolic process GO:2001057 3 0.014
regulation of locomotion GO:0040012 329 0.014
small molecule biosynthetic process GO:0044283 157 0.014
epidermal growth factor activated receptor transactivation by g protein coupled receptor signaling pathway GO:0035625 4 0.014
negative regulation of apoptotic process GO:0043066 316 0.014
Rat
peptidyl tyrosine modification GO:0018212 170 0.014
regulation of cell differentiation GO:0045595 393 0.014
protein localization to organelle GO:0033365 280 0.014
protein modification by small protein conjugation GO:0032446 342 0.014
regulation of intracellular transport GO:0032386 195 0.014
nervous system development GO:0007399 293 0.014
negative regulation of intracellular signal transduction GO:1902532 183 0.014
tripartite regional subdivision GO:0007351 2 0.014
purine ribonucleoside catabolic process GO:0046130 398 0.014
detection of chemical stimulus GO:0009593 55 0.014
fatty acid metabolic process GO:0006631 115 0.013
guanosine containing compound catabolic process GO:1901069 239 0.013
positive regulation of nucleotide metabolic process GO:0045981 230 0.013
Rat
detection of stimulus GO:0051606 85 0.013
organonitrogen compound biosynthetic process GO:1901566 200 0.013
Rat
cellular chemical homeostasis GO:0055082 180 0.013
regulation of protein maturation GO:1903317 150 0.013
associative learning GO:0008306 1 0.013
positive regulation of protein kinase activity GO:0045860 190 0.013
tissue regeneration GO:0042246 3 0.013
cardiac muscle cell contraction GO:0086003 4 0.013
cell growth GO:0016049 160 0.013
peptidyl tyrosine phosphorylation GO:0018108 170 0.013
regulation of mapk cascade GO:0043408 262 0.013
growth GO:0040007 202 0.013
organic acid biosynthetic process GO:0016053 97 0.013
cellular response to endogenous stimulus GO:0071495 336 0.013
regulation of protein processing GO:0070613 150 0.013
reactive oxygen species metabolic process GO:0072593 75 0.013
modification dependent protein catabolic process GO:0019941 209 0.013
positive regulation of developmental process GO:0051094 314 0.013
regulation of protein catabolic process GO:0042176 155 0.013
organophosphate biosynthetic process GO:0090407 163 0.013
Rat
proteasomal protein catabolic process GO:0010498 176 0.013
carbohydrate metabolic process GO:0005975 207 0.013
posttranscriptional regulation of gene expression GO:0010608 213 0.013
secretion by cell GO:0032940 226 0.013
negative regulation of developmental process GO:0051093 247 0.013
carboxylic acid biosynthetic process GO:0046394 97 0.013
rhythmic behavior GO:0007622 2 0.012
syncytium formation by plasma membrane fusion GO:0000768 2 0.012
adult locomotory behavior GO:0008344 1 0.012
positive regulation of programmed cell death GO:0043068 249 0.012
regulation of cellular component biogenesis GO:0044087 281 0.012
negative regulation of protein maturation GO:1903318 142 0.012
regulation of cell migration GO:0030334 289 0.012
compound eye development GO:0048749 1 0.012
cell cycle phase transition GO:0044770 173 0.012
oxidation reduction process GO:0055114 396 0.012
cellular protein complex assembly GO:0043623 188 0.012
regulation of multi organism process GO:0043900 157 0.012
regulation of cell adhesion GO:0030155 166 0.012
cell development GO:0048468 328 0.012
Rat
cellular response to oxygen containing compound GO:1901701 276 0.012
single organism carbohydrate metabolic process GO:0044723 193 0.012
regulation of synaptic plasticity GO:0048167 3 0.012
regulation of endopeptidase activity GO:0052548 170 0.012
cell projection organization GO:0030030 252 0.012
chromatin organization GO:0006325 351 0.012
negative regulation of phosphorylation GO:0042326 174 0.012
cell activation GO:0001775 213 0.012
regulation of reactive oxygen species metabolic process GO:2000377 41 0.012
rna processing GO:0006396 255 0.012
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.012
guanosine containing compound metabolic process GO:1901068 244 0.012
defense response to fungus GO:0050832 4 0.012
immune effector process GO:0002252 159 0.012
cell division GO:0051301 168 0.012
sequestering of metal ion GO:0051238 24 0.012
response to growth factor GO:0070848 205 0.012
regulation of purine nucleotide catabolic process GO:0033121 205 0.012
cell fate determination GO:0001709 3 0.012
negative regulation of protein processing GO:0010955 142 0.012
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.012
organelle assembly GO:0070925 176 0.012
regulation of peptidase activity GO:0052547 180 0.012
modification dependent macromolecule catabolic process GO:0043632 212 0.012
negative regulation of cell proliferation GO:0008285 228 0.012
Rat
negative regulation of interleukin 13 secretion GO:2000666 1 0.012
nitrogen compound transport GO:0071705 191 0.012
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.012
gtp catabolic process GO:0006184 237 0.012
circadian behavior GO:0048512 2 0.012
microtubule based process GO:0007017 210 0.012
mitotic cell cycle phase transition GO:0044772 162 0.012
chromatin modification GO:0016568 298 0.012
limbic system development GO:0021761 3 0.012
endomembrane system organization GO:0010256 196 0.012
transmembrane transport GO:0055085 399 0.012
cation homeostasis GO:0055080 189 0.012
covalent chromatin modification GO:0016569 254 0.012
nerve development GO:0021675 4 0.012
peripheral nervous system development GO:0007422 2 0.012
negative regulation of proteolysis GO:0045861 132 0.011
embryonic epithelial tube formation GO:0001838 4 0.011
actin mediated cell contraction GO:0070252 12 0.011
ubiquitin dependent protein catabolic process GO:0006511 206 0.011
response to lipid GO:0033993 206 0.011
regulation of nucleoside metabolic process GO:0009118 209 0.011
gtp metabolic process GO:0046039 239 0.011
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.011
positive regulation of cytokine production GO:0001819 167 0.011
regulation of meiotic cell cycle GO:0051445 4 0.011
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.011
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.011
single organism cell adhesion GO:0098602 179 0.011
histone modification GO:0016570 251 0.011
leukocyte activation GO:0045321 164 0.011
monocarboxylic acid metabolic process GO:0032787 185 0.011
sequestering of calcium ion GO:0051208 17 0.011
regulation of nucleotide catabolic process GO:0030811 205 0.011
cation transport GO:0006812 331 0.011
positive regulation of locomotion GO:0040017 186 0.011
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.011
actin cytoskeleton organization GO:0030036 207 0.011
hindbrain development GO:0030902 3 0.011
positive regulation of mapk cascade GO:0043410 190 0.011
metal ion homeostasis GO:0055065 169 0.011
cellular response to growth factor stimulus GO:0071363 197 0.011
dna repair GO:0006281 198 0.011
positive regulation of gtpase activity GO:0043547 166 0.011
positive regulation of nucleotide catabolic process GO:0030813 185 0.011
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.011
cellular cation homeostasis GO:0030003 163 0.011
rna interference GO:0016246 4 0.011
regulation of cytoplasmic transport GO:1903649 149 0.011
protein secretion GO:0009306 98 0.011
meiosis i GO:0007127 4 0.011
regulation of cell motility GO:2000145 299 0.011
positive regulation of gtp catabolic process GO:0033126 166 0.011
purine nucleoside monophosphate metabolic process GO:0009126 186 0.011
response to virus GO:0009615 126 0.011
tube closure GO:0060606 3 0.011
visual behavior GO:0007632 2 0.011
neural tube closure GO:0001843 3 0.011
protein localization to membrane GO:0072657 160 0.011
negative regulation of protein phosphorylation GO:0001933 140 0.011
positive regulation of nucleoside metabolic process GO:0045979 186 0.011
meiotic chromosome segregation GO:0045132 4 0.011
epithelium development GO:0060429 227 0.011
enzyme linked receptor protein signaling pathway GO:0007167 303 0.010
metencephalon development GO:0022037 2 0.010
anatomical structure formation involved in morphogenesis GO:0048646 284 0.010
regulation of cell growth GO:0001558 135 0.010
negative regulation of locomotion GO:0040013 118 0.010
positive regulation of organelle organization GO:0010638 195 0.010
sensory perception GO:0007600 103 0.010
nucleoside monophosphate metabolic process GO:0009123 191 0.010
positive regulation of cellular component biogenesis GO:0044089 158 0.010
response to cytokine GO:0034097 232 0.010
response to nitrogen compound GO:1901698 184 0.010
regulation of dna metabolic process GO:0051052 153 0.010
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.010
cellular response to cytokine stimulus GO:0071345 181 0.010
photoreceptor cell differentiation GO:0046530 2 0.010
negative regulation of transport GO:0051051 176 0.010
response to axon injury GO:0048678 1 0.010
regulation of gtpase activity GO:0043087 180 0.010
metal ion transport GO:0030001 272 0.010
protein targeting GO:0006605 187 0.010
negative regulation of cell cycle GO:0045786 193 0.010
small molecule catabolic process GO:0044282 92 0.010
secretion GO:0046903 254 0.010
positive regulation of protein transport GO:0051222 135 0.010
negative regulation of transferase activity GO:0051348 124 0.010
regulation of cytoskeleton organization GO:0051493 177 0.010
myoblast fusion GO:0007520 1 0.010
glial cell migration GO:0008347 4 0.010
positive regulation of secretion GO:0051047 116 0.010

RXFP2 disease predictions

Disease DO term ID Size Probability Func Analog Org
sensory system disease DOID:0050155 203 0.028
nervous system disease DOID:863 431 0.028
disease of metabolism DOID:0014667 295 0.024
eye and adnexa disease DOID:1492 150 0.022
eye disease DOID:5614 149 0.022
inherited metabolic disorder DOID:655 242 0.020
musculoskeletal system disease DOID:17 223 0.018
retinal disease DOID:5679 118 0.016
disease of cellular proliferation DOID:14566 174 0.015
cancer DOID:162 167 0.014
central nervous system disease DOID:331 186 0.014
immune system disease DOID:2914 155 0.014
retinal degeneration DOID:8466 89 0.013
organ system cancer DOID:0050686 164 0.013
connective tissue disease DOID:65 109 0.011
bone disease DOID:0080001 88 0.011
physical disorder DOID:0080015 41 0.006