Homo sapiens

35 known processes

EIF5B

eukaryotic translation initiation factor 5B

(Aliases: KIAA0741,DKFZp434I036,IF2,FLJ10524)

EIF5B biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
post embryonic development GO:0009791 2 0.799
Worm
vesicle mediated transport GO:0016192 371 0.591
ncrna processing GO:0034470 83 0.557
Yeast
ncrna metabolic process GO:0034660 108 0.464
Yeast
ribonucleoprotein complex biogenesis GO:0022613 116 0.446
Yeast
rrna metabolic process GO:0016072 40 0.429
Yeast
maturation of ssu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:0000462 1 0.393
Yeast
oogenesis GO:0048477 2 0.350
endocytosis GO:0006897 159 0.318
multicellular organismal aging GO:0010259 3 0.295
female gamete generation GO:0007292 2 0.285
rrna processing GO:0006364 35 0.274
Yeast
ribosome biogenesis GO:0042254 48 0.266
Yeast
rna processing GO:0006396 255 0.239
Yeast
maturation of ssu rrna GO:0030490 3 0.226
Yeast
determination of adult lifespan GO:0008340 2 0.160
maturation of 5 8s rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:0000466 2 0.152
purine nucleoside triphosphate catabolic process GO:0009146 392 0.139
Yeast
posttranscriptional regulation of gene expression GO:0010608 213 0.133
maturation of 5 8s rrna GO:0000460 8 0.127
rna 5 end processing GO:0000966 2 0.125
regulation of nucleocytoplasmic transport GO:0046822 98 0.124
cellular macromolecular complex assembly GO:0034622 324 0.120
Yeast
embryo development GO:0009790 123 0.113
Worm
nucleoside phosphate catabolic process GO:1901292 412 0.107
Yeast
purine ribonucleotide catabolic process GO:0009154 404 0.106
Yeast
nucleic acid phosphodiester bond hydrolysis GO:0090305 102 0.104
glycosyl compound catabolic process GO:1901658 413 0.095
Yeast
ribonucleoside catabolic process GO:0042454 406 0.093
Yeast
cell development GO:0048468 328 0.093
intracellular protein transport GO:0006886 270 0.092
purine nucleotide catabolic process GO:0006195 405 0.091
Yeast
reproduction GO:0000003 63 0.089
Worm
purine ribonucleoside catabolic process GO:0046130 398 0.088
Yeast
actin filament based process GO:0030029 224 0.082
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.080
Yeast
nucleotide catabolic process GO:0009166 408 0.080
Yeast
cytoplasmic transport GO:0016482 379 0.077
reproductive process GO:0022414 106 0.074
neuron differentiation GO:0030182 138 0.074
receptor mediated endocytosis GO:0006898 84 0.073
cellular component morphogenesis GO:0032989 314 0.069
cellular amino acid metabolic process GO:0006520 116 0.068
response to oxygen containing compound GO:1901700 369 0.065
single organism reproductive process GO:0044702 98 0.065
muscle structure development GO:0061061 98 0.063
nuclear transport GO:0051169 179 0.062
actin cytoskeleton organization GO:0030036 207 0.061
nervous system development GO:0007399 293 0.060
positive regulation of transport GO:0051050 336 0.058
regulation of protein localization GO:0032880 296 0.056
regulation of cell differentiation GO:0045595 393 0.055
neurogenesis GO:0022008 169 0.055
positive regulation of intracellular protein transport GO:0090316 76 0.052
purine containing compound catabolic process GO:0072523 411 0.052
Yeast
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.052
purine nucleoside triphosphate metabolic process GO:0009144 412 0.051
Yeast
organophosphate catabolic process GO:0046434 430 0.051
Yeast
rna phosphodiester bond hydrolysis GO:0090501 35 0.050
negative regulation of apoptotic process GO:0043066 316 0.050
small gtpase mediated signal transduction GO:0007264 78 0.050
establishment of protein localization to organelle GO:0072594 172 0.050
regulation of anatomical structure morphogenesis GO:0022603 286 0.048
regulation of protein targeting GO:1903533 91 0.048
mitotic cell cycle phase transition GO:0044772 162 0.047
response to cytokine GO:0034097 232 0.046
ribonucleoside triphosphate metabolic process GO:0009199 412 0.046
Yeast
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.044
Yeast
nucleoside triphosphate metabolic process GO:0009141 422 0.043
Yeast
ribonucleoside triphosphate catabolic process GO:0009203 391 0.042
Yeast
cell projection organization GO:0030030 252 0.042
regulation of cellular amine metabolic process GO:0033238 11 0.042
nucleocytoplasmic transport GO:0006913 176 0.042
angiogenesis GO:0001525 147 0.041
response to organic cyclic compound GO:0014070 204 0.041
regulation of binding GO:0051098 111 0.040
maturation of lsu rrna GO:0000470 3 0.040
regulation of translation GO:0006417 89 0.040
ribosomal small subunit biogenesis GO:0042274 13 0.039
Yeast
cytokine mediated signaling pathway GO:0019221 109 0.039
positive regulation of cellular catabolic process GO:0031331 284 0.038
positive regulation of intracellular transport GO:0032388 104 0.038
negative regulation of programmed cell death GO:0043069 321 0.037
positive regulation of cytoplasmic transport GO:1903651 82 0.037
single organism cellular localization GO:1902580 332 0.037
sex differentiation GO:0007548 45 0.037
positive regulation of developmental process GO:0051094 314 0.036
negative regulation of protein metabolic process GO:0051248 391 0.035
regulation of meiotic cell cycle GO:0051445 4 0.035
cell morphogenesis GO:0000902 296 0.035
mitotic cell cycle GO:0000278 326 0.035
meiosis i GO:0007127 4 0.034
gonad development GO:0008406 34 0.034
rrna containing ribonucleoprotein complex export from nucleus GO:0071428 4 0.033
regulation of intracellular protein transport GO:0033157 123 0.033
ras protein signal transduction GO:0007265 73 0.032
purine nucleoside monophosphate metabolic process GO:0009126 186 0.031
purine nucleoside catabolic process GO:0006152 398 0.031
Yeast
vasculature development GO:0001944 181 0.030
protein localization to organelle GO:0033365 280 0.030
positive regulation of phosphorylation GO:0042327 394 0.029
regulation of cellular component biogenesis GO:0044087 281 0.029
reproductive structure development GO:0048608 55 0.029
negative regulation of cellular protein metabolic process GO:0032269 353 0.029
regulation of actin filament based process GO:0032970 141 0.029
nucleoside catabolic process GO:0009164 408 0.028
Yeast
purine ribonucleoside metabolic process GO:0046128 437 0.028
Yeast
regulation of protein import into nucleus GO:0042306 78 0.028
dna recombination GO:0006310 77 0.028
positive regulation of protein transport GO:0051222 135 0.027
segmentation GO:0035282 4 0.027
negative regulation of hydrolase activity GO:0051346 182 0.026
multicellular organismal reproductive process GO:0048609 40 0.026
behavior GO:0007610 112 0.026
positive regulation of catabolic process GO:0009896 310 0.026
defense response GO:0006952 315 0.026
neuron development GO:0048666 113 0.025
oocyte development GO:0048599 1 0.025
ribonucleotide catabolic process GO:0009261 405 0.025
Yeast
neuromuscular junction development GO:0007528 3 0.025
regulation of nervous system development GO:0051960 88 0.025
regulation of cell morphogenesis GO:0022604 153 0.024
regulation of ras protein signal transduction GO:0046578 155 0.024
response to reactive oxygen species GO:0000302 61 0.023
generation of neurons GO:0048699 152 0.023
regulation of vasculature development GO:1901342 97 0.023
response to abiotic stimulus GO:0009628 336 0.023
regulation of cytoplasmic transport GO:1903649 149 0.023
cellular response to oxygen containing compound GO:1901701 276 0.023
negative regulation of developmental process GO:0051093 247 0.023
growth GO:0040007 202 0.023
actin filament organization GO:0007015 128 0.023
regulation of angiogenesis GO:0045765 92 0.023
regulation of protein kinase activity GO:0045859 289 0.022
neuron projection development GO:0031175 106 0.022
regulation of small gtpase mediated signal transduction GO:0051056 156 0.022
negative regulation of cell cycle GO:0045786 193 0.022
single organism nuclear import GO:1902593 104 0.022
negative regulation of mitotic cell cycle phase transition GO:1901991 85 0.022
regeneration GO:0031099 4 0.022
protein targeting GO:0006605 187 0.022
negative regulation of cell death GO:0060548 345 0.022
reproductive system development GO:0061458 56 0.022
regulation of cellular amino acid metabolic process GO:0006521 6 0.021
regulation of cell cycle process GO:0010564 266 0.021
cell projection morphogenesis GO:0048858 129 0.021
multicellular organism reproduction GO:0032504 42 0.021
regulation of cell division GO:0051302 116 0.020
meiotic chromosome segregation GO:0045132 4 0.020
blood vessel development GO:0001568 172 0.020
negative regulation of catalytic activity GO:0043086 335 0.020
organelle assembly GO:0070925 176 0.020
Yeast
multi organism reproductive process GO:0044703 54 0.019
positive regulation of protein import into nucleus GO:0042307 46 0.019
blastoderm segmentation GO:0007350 2 0.019
positive regulation of proteolysis GO:0045862 142 0.019
regulation of neuron differentiation GO:0045664 70 0.019
protein import GO:0017038 130 0.019
regulation of establishment of protein localization GO:0070201 242 0.019
regulation of protein transport GO:0051223 213 0.019
blood vessel morphogenesis GO:0048514 162 0.018
protein catabolic process GO:0030163 325 0.018
guanosine containing compound catabolic process GO:1901069 239 0.018
Yeast
regulation of locomotion GO:0040012 329 0.018
regulation of protein localization to nucleus GO:1900180 85 0.018
embryo development ending in birth or egg hatching GO:0009792 34 0.018
Worm
response to interferon gamma GO:0034341 39 0.018
regulation of mitotic cell cycle phase transition GO:1901990 118 0.017
signal transduction by phosphorylation GO:0023014 297 0.017
amine metabolic process GO:0009308 44 0.017
cell aging GO:0007569 52 0.017
positive regulation of nucleocytoplasmic transport GO:0046824 54 0.017
positive regulation of meiotic cell cycle GO:0051446 2 0.017
negative regulation of phosphorus metabolic process GO:0010563 267 0.017
anatomical structure homeostasis GO:0060249 100 0.017
biological adhesion GO:0022610 331 0.017
sexual reproduction GO:0019953 37 0.017
cellular ketone metabolic process GO:0042180 80 0.017
establishment of protein localization to membrane GO:0090150 121 0.017
oocyte differentiation GO:0009994 2 0.017
positive regulation of apoptotic process GO:0043065 246 0.017
negative regulation of protein processing GO:0010955 142 0.017
negative regulation of cell proliferation GO:0008285 228 0.017
ribonucleoside monophosphate metabolic process GO:0009161 187 0.017
cell cycle phase transition GO:0044770 173 0.016
anterior posterior axis specification embryo GO:0008595 2 0.016
response to calcium ion GO:0051592 46 0.016
translation GO:0006412 132 0.016
tissue migration GO:0090130 119 0.016
regulation of cytokinesis GO:0032465 45 0.016
recombinational repair GO:0000725 50 0.016
negative regulation of phosphate metabolic process GO:0045936 267 0.016
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.016
regulation of cell cycle GO:0051726 393 0.016
protein localization to nucleus GO:0034504 136 0.016
regulation of cell motility GO:2000145 299 0.015
positive regulation of cellular amine metabolic process GO:0033240 7 0.015
positive regulation of programmed cell death GO:0043068 249 0.015
cellular response to cytokine stimulus GO:0071345 181 0.015
regulation of protein serine threonine kinase activity GO:0071900 179 0.015
cellular amine metabolic process GO:0044106 41 0.015
regulation of cellular component movement GO:0051270 334 0.015
regulation of dephosphorylation GO:0035303 96 0.015
developmental process involved in reproduction GO:0003006 66 0.015
regulation of cytoskeleton organization GO:0051493 177 0.015
positive regulation of cell migration GO:0030335 172 0.015
mapk cascade GO:0000165 288 0.015
single organism membrane organization GO:0044802 268 0.015
cell junction assembly GO:0034329 67 0.015
cell division GO:0051301 168 0.014
negative regulation of mitotic cell cycle GO:0045930 102 0.014
membrane organization GO:0061024 292 0.014
cell growth GO:0016049 160 0.014
chromatin organization GO:0006325 351 0.014
circulatory system development GO:0072359 262 0.014
regulation of response to external stimulus GO:0032101 222 0.014
regulation of intracellular transport GO:0032386 195 0.014
regulation of protein complex assembly GO:0043254 147 0.014
chromosome segregation GO:0007059 114 0.014
photoreceptor cell differentiation GO:0046530 2 0.014
regulation of purine nucleotide metabolic process GO:1900542 264 0.014
negative regulation of dna metabolic process GO:0051053 57 0.014
regulation of body fluid levels GO:0050878 99 0.014
negative regulation of phosphatase activity GO:0010923 61 0.014
guanosine containing compound metabolic process GO:1901068 244 0.014
Yeast
cell cycle checkpoint GO:0000075 117 0.014
protein maturation GO:0051604 233 0.014
cell part morphogenesis GO:0032990 137 0.014
response to nitrogen compound GO:1901698 184 0.013
methylation GO:0032259 106 0.013
ribonucleoprotein complex assembly GO:0022618 78 0.013
Yeast
negative regulation of multicellular organismal process GO:0051241 317 0.013
positive regulation of protein localization to nucleus GO:1900182 48 0.013
cell junction organization GO:0034330 79 0.013
tripartite regional subdivision GO:0007351 2 0.013
protein localization to membrane GO:0072657 160 0.013
cell adhesion GO:0007155 325 0.013
regulation of neurogenesis GO:0050767 82 0.013
nucleoside triphosphate catabolic process GO:0009143 394 0.013
Yeast
regulation of cell shape GO:0008360 48 0.013
regulation of cellular ketone metabolic process GO:0010565 50 0.013
protein modification by small protein conjugation GO:0032446 342 0.013
response to growth factor GO:0070848 205 0.013
anatomical structure formation involved in morphogenesis GO:0048646 284 0.013
i kappab kinase nf kappab signaling GO:0007249 166 0.013
positive regulation of cell death GO:0010942 263 0.013
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.013
regulation of transferase activity GO:0051338 355 0.013
dephosphorylation GO:0016311 209 0.013
erk1 and erk2 cascade GO:0070371 104 0.013
negative regulation of cell differentiation GO:0045596 171 0.012
microtubule based process GO:0007017 210 0.012
protein import into nucleus GO:0006606 104 0.012
regulation of cell migration GO:0030334 289 0.012
development of primary sexual characteristics GO:0045137 35 0.012
chromatin modification GO:0016568 298 0.012
n terminal protein amino acid modification GO:0031365 13 0.012
response to organonitrogen compound GO:0010243 156 0.012
positive regulation of cell differentiation GO:0045597 211 0.012
striated muscle contraction GO:0006941 52 0.012
nucleoside monophosphate catabolic process GO:0009125 159 0.012
neuron projection morphogenesis GO:0048812 50 0.011
nuclear import GO:0051170 106 0.011
lipid metabolic process GO:0006629 381 0.011
gamete generation GO:0007276 25 0.011
regulation of protein catabolic process GO:0042176 155 0.011
nitrogen compound transport GO:0071705 191 0.011
dna conformation change GO:0071103 113 0.011
ameboidal type cell migration GO:0001667 135 0.011
cardiovascular system development GO:0072358 262 0.011
regulation of cell development GO:0060284 161 0.011
atp metabolic process GO:0046034 176 0.011
microtubule cytoskeleton organization GO:0000226 176 0.011
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.011
aging GO:0007568 66 0.011
multi multicellular organism process GO:0044706 18 0.011
negative regulation of intracellular signal transduction GO:1902532 183 0.011
cell morphogenesis involved in neuron differentiation GO:0048667 44 0.010
multi organism cellular process GO:0044764 156 0.010
protein autophosphorylation GO:0046777 123 0.010
protein ubiquitination GO:0016567 314 0.010
response to hydrogen peroxide GO:0042542 40 0.010
positive regulation of cellular component organization GO:0051130 376 0.010
regulation of proteasomal protein catabolic process GO:0061136 87 0.010
cellular protein complex assembly GO:0043623 188 0.010
positive regulation of cellular component biogenesis GO:0044089 158 0.010
negative regulation of protein modification process GO:0031400 200 0.010
positive regulation of growth GO:0045927 58 0.010
brain development GO:0007420 97 0.010
response to oxidative stress GO:0006979 121 0.010
spermatid differentiation GO:0048515 4 0.010
head development GO:0060322 108 0.010
rna interference GO:0016246 4 0.010
ribonucleoprotein complex localization GO:0071166 4 0.010

EIF5B disease predictions

Disease DO term ID Size Probability Func Analog Org
musculoskeletal system disease DOID:17 223 0.021
myopathy DOID:423 104 0.020
muscular disease DOID:0080000 114 0.020
muscle tissue disease DOID:66 113 0.020