Homo sapiens

6 known processes

HARS2

histidyl-tRNA synthetase 2, mitochondrial (putative)

(Aliases: HARSL,HO3,HARSR)

HARS2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
post embryonic development GO:0009791 2 0.147
cellular amino acid metabolic process GO:0006520 116 0.082
Yeast
vesicle mediated transport GO:0016192 371 0.059
multicellular organismal aging GO:0010259 3 0.053
determination of adult lifespan GO:0008340 2 0.052
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.051
ribonucleoside triphosphate metabolic process GO:0009199 412 0.051
regulation of cellular ketone metabolic process GO:0010565 50 0.047
purine nucleoside triphosphate metabolic process GO:0009144 412 0.045
purine ribonucleoside metabolic process GO:0046128 437 0.045
cellular ketone metabolic process GO:0042180 80 0.041
ribonucleoside catabolic process GO:0042454 406 0.041
purine nucleotide catabolic process GO:0006195 405 0.041
mitochondrion organization GO:0007005 156 0.038
Yeast
organophosphate catabolic process GO:0046434 430 0.038
amine metabolic process GO:0009308 44 0.038
regulation of cellular amino acid metabolic process GO:0006521 6 0.038
nucleotide catabolic process GO:0009166 408 0.037
cellular macromolecule catabolic process GO:0044265 380 0.037
regulation of cellular amine metabolic process GO:0033238 11 0.036
ribonucleoside triphosphate catabolic process GO:0009203 391 0.036
negative regulation of protein metabolic process GO:0051248 391 0.036
purine nucleoside triphosphate catabolic process GO:0009146 392 0.035
nucleoside triphosphate metabolic process GO:0009141 422 0.035
nucleoside catabolic process GO:0009164 408 0.035
cellular amine metabolic process GO:0044106 41 0.034
purine ribonucleotide catabolic process GO:0009154 404 0.034
purine ribonucleoside catabolic process GO:0046130 398 0.034
cytoplasmic transport GO:0016482 379 0.034
nucleoside phosphate catabolic process GO:1901292 412 0.032
negative regulation of cellular protein metabolic process GO:0032269 353 0.032
glycosyl compound catabolic process GO:1901658 413 0.032
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.031
growth GO:0040007 202 0.031
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.030
oogenesis GO:0048477 2 0.029
positive regulation of catabolic process GO:0009896 310 0.029
neuromuscular junction development GO:0007528 3 0.029
nucleoside triphosphate catabolic process GO:0009143 394 0.029
negative regulation of catalytic activity GO:0043086 335 0.029
positive regulation of cellular catabolic process GO:0031331 284 0.029
ribonucleotide catabolic process GO:0009261 405 0.028
regulation of kinase activity GO:0043549 314 0.027
female gamete generation GO:0007292 2 0.027
immune response GO:0006955 307 0.027
purine nucleoside catabolic process GO:0006152 398 0.027
positive regulation of cellular component organization GO:0051130 376 0.026
purine containing compound catabolic process GO:0072523 411 0.025
locomotory behavior GO:0007626 1 0.025
regulation of meiotic cell cycle GO:0051445 4 0.025
cofactor metabolic process GO:0051186 87 0.025
cellular macromolecular complex assembly GO:0034622 324 0.025
nucleoside monophosphate metabolic process GO:0009123 191 0.025
regulation of transferase activity GO:0051338 355 0.025
negative regulation of phosphorus metabolic process GO:0010563 267 0.024
mrna metabolic process GO:0016071 175 0.024
positive regulation of cellular amine metabolic process GO:0033240 7 0.024
atp metabolic process GO:0046034 176 0.024
positive regulation of nucleotide metabolic process GO:0045981 230 0.023
negative regulation of phosphate metabolic process GO:0045936 267 0.023
mitotic cell cycle process GO:1903047 286 0.023
positive regulation of developmental process GO:0051094 314 0.023
posttranscriptional regulation of gene expression GO:0010608 213 0.022
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.022
protein maturation GO:0051604 233 0.022
ribonucleoside monophosphate metabolic process GO:0009161 187 0.022
positive regulation of hydrolase activity GO:0051345 331 0.022
carbohydrate derivative biosynthetic process GO:1901137 207 0.022
regulation of cell cycle GO:0051726 393 0.021
cellular protein catabolic process GO:0044257 261 0.021
response to abiotic stimulus GO:0009628 336 0.021
regulation of nucleotide metabolic process GO:0006140 269 0.021
mitotic cell cycle GO:0000278 326 0.020
purine nucleoside monophosphate metabolic process GO:0009126 186 0.020
oxidation reduction process GO:0055114 396 0.020
translation GO:0006412 132 0.020
Yeast
regulation of purine nucleotide metabolic process GO:1900542 264 0.020
protein processing GO:0016485 226 0.020
guanosine containing compound metabolic process GO:1901068 244 0.020
regulation of protein kinase activity GO:0045859 289 0.020
actin filament based process GO:0030029 224 0.020
memory GO:0007613 3 0.020
cell development GO:0048468 328 0.020
chromatin organization GO:0006325 351 0.020
lipid metabolic process GO:0006629 381 0.019
guanosine containing compound catabolic process GO:1901069 239 0.019
regulation of growth GO:0040008 165 0.019
endomembrane system organization GO:0010256 196 0.019
adult locomotory behavior GO:0008344 1 0.019
positive regulation of transport GO:0051050 336 0.019
modification dependent macromolecule catabolic process GO:0043632 212 0.019
negative regulation of programmed cell death GO:0043069 321 0.018
mitochondrial rna metabolic process GO:0000959 15 0.018
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.018
protein catabolic process GO:0030163 325 0.018
single organism membrane organization GO:0044802 268 0.018
biological adhesion GO:0022610 331 0.018
regulation of proteolysis GO:0030162 293 0.018
system process GO:0003008 349 0.018
spermatid development GO:0007286 4 0.018
cellular lipid metabolic process GO:0044255 303 0.017
cellular component morphogenesis GO:0032989 314 0.017
cell adhesion GO:0007155 325 0.017
regulation of nucleoside metabolic process GO:0009118 209 0.017
nervous system development GO:0007399 293 0.017
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.017
negative regulation of protein modification process GO:0031400 200 0.017
regeneration GO:0031099 4 0.017
spermatid differentiation GO:0048515 4 0.017
regulation of cell cycle process GO:0010564 266 0.017
defense response GO:0006952 315 0.017
dna repair GO:0006281 198 0.017
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.017
positive regulation of immune system process GO:0002684 283 0.016
response to cytokine GO:0034097 232 0.016
cellular protein complex assembly GO:0043623 188 0.016
embryo development GO:0009790 123 0.016
histone modification GO:0016570 251 0.016
regulation of cytokine production GO:0001817 232 0.016
endocytosis GO:0006897 159 0.016
regulation of nucleotide catabolic process GO:0030811 205 0.016
negative regulation of cell death GO:0060548 345 0.016
negative regulation of cellular amine metabolic process GO:0033239 3 0.016
nitrogen compound transport GO:0071705 191 0.016
ras protein signal transduction GO:0007265 73 0.016
regulation of purine nucleotide catabolic process GO:0033121 205 0.016
negative regulation of apoptotic process GO:0043066 316 0.016
organelle assembly GO:0070925 176 0.016
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.016
innate immune response GO:0045087 178 0.016
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.016
apoptotic signaling pathway GO:0097190 268 0.016
negative regulation of phosphorylation GO:0042326 174 0.015
receptor mediated endocytosis GO:0006898 84 0.015
gtp catabolic process GO:0006184 237 0.015
modification dependent protein catabolic process GO:0019941 209 0.015
negative regulation of cellular component organization GO:0051129 235 0.015
dephosphorylation GO:0016311 209 0.015
regulation of protein processing GO:0070613 150 0.015
cell division GO:0051301 168 0.015
positive regulation of nucleoside metabolic process GO:0045979 186 0.015
ribonucleoside monophosphate catabolic process GO:0009158 158 0.015
mating GO:0007618 1 0.015
positive regulation of nucleotide catabolic process GO:0030813 185 0.015
purine nucleoside monophosphate catabolic process GO:0009128 158 0.015
neurological system process GO:0050877 163 0.015
chromatin modification GO:0016568 298 0.015
membrane organization GO:0061024 292 0.015
interspecies interaction between organisms GO:0044419 156 0.014
regulation of cellular response to stress GO:0080135 244 0.014
macromolecule methylation GO:0043414 97 0.014
coenzyme metabolic process GO:0006732 65 0.014
regulation of gtpase activity GO:0043087 180 0.014
cell cycle phase transition GO:0044770 173 0.014
negative regulation of hydrolase activity GO:0051346 182 0.014
positive regulation of cell death GO:0010942 263 0.014
reactive nitrogen species metabolic process GO:2001057 3 0.014
cell growth GO:0016049 160 0.014
organelle fission GO:0048285 149 0.014
regulation of anatomical structure morphogenesis GO:0022603 286 0.014
positive regulation of gtp catabolic process GO:0033126 166 0.014
blastoderm segmentation GO:0007350 2 0.014
regulation of protein maturation GO:1903317 150 0.014
regulation of viral process GO:0050792 103 0.014
peripheral nervous system development GO:0007422 2 0.014
tissue regeneration GO:0042246 3 0.014
response to external biotic stimulus GO:0043207 261 0.014
cell morphogenesis GO:0000902 296 0.014
secretion by cell GO:0032940 226 0.014
metal ion transport GO:0030001 272 0.014
positive regulation of phosphorylation GO:0042327 394 0.014
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.014
response to other organism GO:0051707 261 0.014
chemical homeostasis GO:0048878 306 0.014
photoreceptor cell differentiation GO:0046530 2 0.014
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.013
negative regulation of kinase activity GO:0033673 106 0.013
regulation of cellular component biogenesis GO:0044087 281 0.013
positive regulation of protein phosphorylation GO:0001934 313 0.013
carbohydrate metabolic process GO:0005975 207 0.013
negative regulation of transferase activity GO:0051348 124 0.013
gtp metabolic process GO:0046039 239 0.013
rna processing GO:0006396 255 0.013
regulation of cellular component movement GO:0051270 334 0.013
regulation of immune response GO:0050776 201 0.013
ubiquitin dependent protein catabolic process GO:0006511 206 0.013
negative regulation of organelle organization GO:0010639 126 0.013
rna interference GO:0016246 4 0.013
positive regulation of programmed cell death GO:0043068 249 0.013
ion transmembrane transport GO:0034220 338 0.013
secretion GO:0046903 254 0.013
transmembrane transport GO:0055085 399 0.013
negative regulation of intracellular signal transduction GO:1902532 183 0.013
negative regulation of protein processing GO:0010955 142 0.013
cytokine production GO:0001816 247 0.013
neurogenesis GO:0022008 169 0.013
proteasomal protein catabolic process GO:0010498 176 0.013
regulation of protein catabolic process GO:0042176 155 0.013
covalent chromatin modification GO:0016569 254 0.013
cellular response to dna damage stimulus GO:0006974 379 0.013
signal transduction by phosphorylation GO:0023014 297 0.013
positive regulation of apoptotic process GO:0043065 246 0.013
atp catabolic process GO:0006200 157 0.013
regulation of mitotic cell cycle GO:0007346 189 0.013
anion transport GO:0006820 161 0.012
visual behavior GO:0007632 2 0.012
response to radiation GO:0009314 151 0.012
negative regulation of multicellular organismal process GO:0051241 317 0.012
anatomical structure formation involved in morphogenesis GO:0048646 284 0.012
regulation of secretion GO:0051046 194 0.012
regulation of dna metabolic process GO:0051052 153 0.012
methylation GO:0032259 106 0.012
response to oxygen containing compound GO:1901700 369 0.012
response to oxidative stress GO:0006979 121 0.012
monocarboxylic acid metabolic process GO:0032787 185 0.012
regulation of protein localization GO:0032880 296 0.012
nucleoside monophosphate catabolic process GO:0009125 159 0.012
oocyte differentiation GO:0009994 2 0.012
cellular response to cytokine stimulus GO:0071345 181 0.012
negative regulation of cell proliferation GO:0008285 228 0.012
regulation of endopeptidase activity GO:0052548 170 0.012
rho protein signal transduction GO:0007266 26 0.012
regulation of meiosis GO:0040020 3 0.012
positive regulation of cell proliferation GO:0008284 301 0.012
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.012
protein acylation GO:0043543 138 0.012
positive regulation of gtpase activity GO:0043547 166 0.012
morphogenesis of embryonic epithelium GO:0016331 4 0.012
ion homeostasis GO:0050801 230 0.012
response to biotic stimulus GO:0009607 276 0.012
organophosphate biosynthetic process GO:0090407 163 0.012
negative regulation of cell cycle GO:0045786 193 0.012
segmentation GO:0035282 4 0.012
rna splicing GO:0008380 131 0.012
viral process GO:0016032 146 0.012
regulation of protein transport GO:0051223 213 0.012
positive regulation of organelle organization GO:0010638 195 0.012
protein localization to organelle GO:0033365 280 0.012
intracellular protein transport GO:0006886 270 0.012
neurotransmitter secretion GO:0007269 4 0.012
regulation of membrane potential GO:0042391 95 0.012
regulation of multi organism process GO:0043900 157 0.012
regulation of intracellular transport GO:0032386 195 0.012
anterior posterior axis specification GO:0009948 2 0.012
negative regulation of protein maturation GO:1903318 142 0.011
negative regulation of proteolysis GO:0045861 132 0.011
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 156 0.011
response to oxygen levels GO:0070482 100 0.011
inner ear morphogenesis GO:0042472 4 0.011
reactive oxygen species biosynthetic process GO:1903409 4 0.011
small gtpase mediated signal transduction GO:0007264 78 0.011
regulation of secretion by cell GO:1903530 177 0.011
positive regulation of synaptic transmission GO:0050806 4 0.011
cell projection organization GO:0030030 252 0.011
cation transport GO:0006812 331 0.011
single organism cellular localization GO:1902580 332 0.011
oocyte development GO:0048599 1 0.011
negative regulation of protein phosphorylation GO:0001933 140 0.011
mapk cascade GO:0000165 288 0.011
regulation of cell motility GO:2000145 299 0.011
actin cytoskeleton organization GO:0030036 207 0.011
associative learning GO:0008306 1 0.011
regulation of cytoskeleton organization GO:0051493 177 0.011
regulation of cell growth GO:0001558 135 0.011
positive regulation of cellular component biogenesis GO:0044089 158 0.011
divalent inorganic cation transport GO:0072511 158 0.011
regulation of mapk cascade GO:0043408 262 0.011
trna aminoacylation for protein translation GO:0006418 8 0.011
Yeast
negative regulation of protein kinase activity GO:0006469 98 0.011
negative regulation of developmental process GO:0051093 247 0.011
golgi vesicle transport GO:0048193 80 0.011
cellular chemical homeostasis GO:0055082 180 0.011
peptidyl lysine modification GO:0018205 144 0.011
chromosome segregation GO:0007059 114 0.011
regulation of synaptic plasticity GO:0048167 3 0.011
regulation of peptidase activity GO:0052547 180 0.011
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.010
negative regulation of growth GO:0045926 97 0.010
endosomal transport GO:0016197 129 0.010
ribose phosphate biosynthetic process GO:0046390 82 0.010
multi organism cellular process GO:0044764 156 0.010
regulation of chromosome organization GO:0033044 103 0.010
defense response to other organism GO:0098542 129 0.010
maintenance of location GO:0051235 112 0.010
immune effector process GO:0002252 159 0.010
lipid biosynthetic process GO:0008610 177 0.010
regulation of gtp catabolic process GO:0033124 180 0.010
i kappab kinase nf kappab signaling GO:0007249 166 0.010
response to hypoxia GO:0001666 96 0.010
single organism carbohydrate metabolic process GO:0044723 193 0.010
cellular homeostasis GO:0019725 196 0.010
positive regulation of cytokine production GO:0001819 167 0.010

HARS2 disease predictions

Disease DO term ID Size Probability Func Analog Org
central nervous system disease DOID:331 186 0.031
nervous system disease DOID:863 431 0.031
musculoskeletal system disease DOID:17 223 0.025
sensory system disease DOID:0050155 203 0.022
eye and adnexa disease DOID:1492 150 0.022
eye disease DOID:5614 149 0.022
muscular disease DOID:0080000 114 0.022
muscle tissue disease DOID:66 113 0.022
disease of metabolism DOID:0014667 295 0.019
retinal disease DOID:5679 118 0.018
usher syndrome DOID:0050439 12 0.017
Human
myopathy DOID:423 104 0.016
inherited metabolic disorder DOID:655 242 0.016
cardiovascular system disease DOID:1287 106 0.015
neurodegenerative disease DOID:1289 102 0.014
cancer DOID:162 167 0.013
disease of cellular proliferation DOID:14566 174 0.013
retinal degeneration DOID:8466 89 0.012
organ system cancer DOID:0050686 164 0.011
perrault syndrome DOID:0050857 4 0.001