|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.754
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.604
|
Mouse Fly |
|
|
peptidyl serine phosphorylation
|
GO:0018105 |
101 |
0.571
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.557
|
|
|
|
peptidyl serine modification
|
GO:0018209 |
106 |
0.552
|
|
|
|
epithelium development
|
GO:0060429 |
227 |
0.524
|
Fly |
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.479
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.472
|
|
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.455
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.395
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.361
|
Fly |
|
|
replacement ossification
|
GO:0036075 |
1 |
0.355
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.342
|
Mouse Fly |
|
|
tube development
|
GO:0035295 |
125 |
0.338
|
|
|
|
tube morphogenesis
|
GO:0035239 |
95 |
0.334
|
|
|
|
anterior posterior axis specification
|
GO:0009948 |
2 |
0.319
|
|
|
|
regulation of cellular component size
|
GO:0032535 |
82 |
0.318
|
Mouse |
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.314
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.305
|
|
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.303
|
|
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.302
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.300
|
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.300
|
Mouse Fly |
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.298
|
Mouse Fly |
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.290
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.279
|
|
|
|
neural crest cell development
|
GO:0014032 |
3 |
0.259
|
|
|
|
embryonic morphogenesis
|
GO:0048598 |
85 |
0.257
|
|
|
|
glial cell migration
|
GO:0008347 |
4 |
0.255
|
|
|
|
digestive system development
|
GO:0055123 |
75 |
0.250
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.244
|
|
|
|
regulation of cell migration
|
GO:0030334 |
289 |
0.240
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.239
|
Mouse Fly |
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.232
|
|
|
|
digestive tract development
|
GO:0048565 |
75 |
0.231
|
|
|
|
generation of neurons
|
GO:0048699 |
152 |
0.230
|
Mouse Fly |
|
|
regulation of neuron differentiation
|
GO:0045664 |
70 |
0.229
|
Mouse Fly |
|
|
regulation of cell adhesion
|
GO:0030155 |
166 |
0.224
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.219
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.215
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.210
|
Mouse Fly |
|
|
neurogenesis
|
GO:0022008 |
169 |
0.198
|
Mouse Fly |
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
4 |
0.197
|
|
|
|
tissue morphogenesis
|
GO:0048729 |
96 |
0.187
|
Fly |
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
83 |
0.184
|
Mouse Fly |
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.178
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.174
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.167
|
|
|
|
ameboidal type cell migration
|
GO:0001667 |
135 |
0.166
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.163
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.160
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.160
|
|
|
|
system process
|
GO:0003008 |
349 |
0.159
|
|
|
|
chondrocyte proliferation
|
GO:0035988 |
4 |
0.157
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.155
|
|
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.153
|
Fly |
|
|
embryonic epithelial tube formation
|
GO:0001838 |
4 |
0.153
|
|
|
|
cell junction organization
|
GO:0034330 |
79 |
0.152
|
|
|
|
cell development
|
GO:0048468 |
328 |
0.152
|
Mouse Fly |
|
|
mapk cascade
|
GO:0000165 |
288 |
0.152
|
|
|
|
regulation of anatomical structure size
|
GO:0090066 |
101 |
0.147
|
Mouse |
|
|
covalent chromatin modification
|
GO:0016569 |
254 |
0.145
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.141
|
|
|
|
nuclear transport
|
GO:0051169 |
179 |
0.139
|
|
|
|
regulation of cell motility
|
GO:2000145 |
299 |
0.137
|
|
|
|
epithelial tube morphogenesis
|
GO:0060562 |
38 |
0.135
|
|
|
|
protein autophosphorylation
|
GO:0046777 |
123 |
0.134
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.132
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.129
|
|
|
|
neuron projection development
|
GO:0031175 |
106 |
0.128
|
Mouse Fly |
|
|
cell projection organization
|
GO:0030030 |
252 |
0.128
|
Mouse Fly |
|
|
actin filament organization
|
GO:0007015 |
128 |
0.126
|
|
|
|
retinal ganglion cell axon guidance
|
GO:0031290 |
2 |
0.126
|
|
|
|
protein processing
|
GO:0016485 |
226 |
0.125
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.125
|
|
|
|
response to hormone
|
GO:0009725 |
175 |
0.124
|
|
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.123
|
Mouse Fly |
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.118
|
|
|
|
regulation of meiotic cell cycle
|
GO:0051445 |
4 |
0.117
|
|
|
|
synaptic transmission
|
GO:0007268 |
61 |
0.117
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.117
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.116
|
|
|
|
regulation of nucleocytoplasmic transport
|
GO:0046822 |
98 |
0.112
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.111
|
|
|
|
protein maturation
|
GO:0051604 |
233 |
0.111
|
|
|
|
protein targeting to nucleus
|
GO:0044744 |
104 |
0.109
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.108
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.106
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.106
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.104
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.104
|
|
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.103
|
Mouse Fly |
|
|
mesenchyme development
|
GO:0060485 |
59 |
0.102
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.101
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.101
|
|
|
|
astrocyte cell migration
|
GO:0043615 |
1 |
0.101
|
|
|
|
neural tube formation
|
GO:0001841 |
3 |
0.100
|
|
|
|
regulation of cellular component movement
|
GO:0051270 |
334 |
0.100
|
|
|
|
digestive tract morphogenesis
|
GO:0048546 |
56 |
0.100
|
|
|
|
neural crest cell migration
|
GO:0001755 |
2 |
0.099
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.099
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.096
|
Worm |
|
|
negative regulation of protein processing
|
GO:0010955 |
142 |
0.095
|
|
|
|
primary neural tube formation
|
GO:0014020 |
3 |
0.095
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.094
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.092
|
|
|
|
gastrulation
|
GO:0007369 |
51 |
0.092
|
|
|
|
protein targeting
|
GO:0006605 |
187 |
0.090
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.090
|
|
|
|
internal protein amino acid acetylation
|
GO:0006475 |
101 |
0.089
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.089
|
Mouse Fly |
|
|
peptidyl lysine acetylation
|
GO:0018394 |
101 |
0.087
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.085
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.085
|
|
|
|
cell migration involved in gastrulation
|
GO:0042074 |
1 |
0.084
|
|
|
|
histone acetylation
|
GO:0016573 |
93 |
0.084
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.084
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.084
|
Mouse |
|
|
cellular protein complex assembly
|
GO:0043623 |
188 |
0.084
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.083
|
|
|
|
regulation of nervous system development
|
GO:0051960 |
88 |
0.082
|
Mouse Fly |
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.081
|
|
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.080
|
|
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.080
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.079
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.078
|
|
|
|
positive regulation of synaptic transmission
|
GO:0050806 |
4 |
0.078
|
|
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.077
|
|
|
|
endothelial cell proliferation
|
GO:0001935 |
65 |
0.077
|
|
|
|
chromatin modification
|
GO:0016568 |
298 |
0.076
|
|
|
|
internal peptidyl lysine acetylation
|
GO:0018393 |
97 |
0.076
|
|
|
|
regulation of peptidase activity
|
GO:0052547 |
180 |
0.075
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.075
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
107 |
0.074
|
Mouse Fly |
|
|
positive regulation of peptidyl serine phosphorylation
|
GO:0033138 |
42 |
0.074
|
|
|
|
positive regulation of mapk cascade
|
GO:0043410 |
190 |
0.073
|
|
|
|
neuron development
|
GO:0048666 |
113 |
0.073
|
Mouse Fly |
|
|
cell cell junction organization
|
GO:0045216 |
69 |
0.073
|
|
|
|
cell part morphogenesis
|
GO:0032990 |
137 |
0.072
|
Mouse Fly |
|
|
positive regulation of proteolysis
|
GO:0045862 |
142 |
0.072
|
|
|
|
cell junction assembly
|
GO:0034329 |
67 |
0.071
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
123 |
0.071
|
|
|
|
negative regulation of protein serine threonine kinase activity
|
GO:0071901 |
57 |
0.070
|
|
|
|
collagen catabolic process
|
GO:0030574 |
10 |
0.070
|
|
|
|
response to oxidative stress
|
GO:0006979 |
121 |
0.070
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.070
|
|
|
|
oocyte development
|
GO:0048599 |
1 |
0.069
|
|
|
|
anterior posterior axis specification embryo
|
GO:0008595 |
2 |
0.068
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.068
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
0.068
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.067
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.066
|
|
|
|
cell cell signaling
|
GO:0007267 |
155 |
0.066
|
|
|
|
regulation of neuron projection development
|
GO:0010975 |
57 |
0.066
|
Mouse Fly |
|
|
regulation of glial cell proliferation
|
GO:0060251 |
4 |
0.066
|
|
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.066
|
|
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.066
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.065
|
|
|
|
protein acylation
|
GO:0043543 |
138 |
0.065
|
|
|
|
regulation of actin polymerization or depolymerization
|
GO:0008064 |
56 |
0.065
|
|
|
|
circulatory system development
|
GO:0072359 |
262 |
0.065
|
|
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.065
|
Mouse Fly |
|
|
regulation of actin filament polymerization
|
GO:0030833 |
50 |
0.064
|
|
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.064
|
|
|
|
compound eye development
|
GO:0048749 |
1 |
0.064
|
Fly |
|
|
circadian behavior
|
GO:0048512 |
2 |
0.063
|
|
|
|
protein import
|
GO:0017038 |
130 |
0.063
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.063
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.063
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.063
|
Worm |
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.062
|
|
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.062
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.062
|
|
|
|
regulation of protein processing
|
GO:0070613 |
150 |
0.061
|
|
|
|
regulation of protein polymerization
|
GO:0032271 |
63 |
0.061
|
|
|
|
embryo development
|
GO:0009790 |
123 |
0.061
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.061
|
|
|
|
negative regulation of peptidase activity
|
GO:0010466 |
91 |
0.061
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.061
|
|
|
|
blood vessel development
|
GO:0001568 |
172 |
0.060
|
|
|
|
endochondral ossification
|
GO:0001958 |
1 |
0.060
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.059
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.059
|
|
|
|
receptor metabolic process
|
GO:0043112 |
81 |
0.059
|
|
|
|
oocyte differentiation
|
GO:0009994 |
2 |
0.058
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.058
|
|
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.057
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.057
|
|
|
|
chemotaxis
|
GO:0006935 |
157 |
0.057
|
|
|
|
tripartite regional subdivision
|
GO:0007351 |
2 |
0.057
|
|
|
|
positive regulation of intracellular transport
|
GO:0032388 |
104 |
0.056
|
|
|
|
positive regulation of protein transport
|
GO:0051222 |
135 |
0.056
|
|
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.056
|
|
|
|
endochondral bone morphogenesis
|
GO:0060350 |
3 |
0.056
|
|
|
|
regulation of multi organism process
|
GO:0043900 |
157 |
0.056
|
|
|
|
peptidyl threonine phosphorylation
|
GO:0018107 |
41 |
0.055
|
|
|
|
regulation of peptidyl serine phosphorylation
|
GO:0033135 |
50 |
0.055
|
|
|
|
regulation of cytokine production
|
GO:0001817 |
232 |
0.055
|
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
170 |
0.055
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.054
|
|
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.054
|
|
|
|
chordate embryonic development
|
GO:0043009 |
34 |
0.054
|
|
|
|
response to hypoxia
|
GO:0001666 |
96 |
0.054
|
|
|
|
negative regulation of protein phosphorylation
|
GO:0001933 |
140 |
0.054
|
|
|
|
sensory organ development
|
GO:0007423 |
52 |
0.053
|
Fly |
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.053
|
|
|
|
associative learning
|
GO:0008306 |
1 |
0.053
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.053
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.053
|
Zebrafish |
|
|
rhythmic behavior
|
GO:0007622 |
2 |
0.053
|
|
|
|
cell substrate adherens junction assembly
|
GO:0007045 |
30 |
0.052
|
|
|
|
negative regulation of transport
|
GO:0051051 |
176 |
0.052
|
|
|
|
segmentation
|
GO:0035282 |
4 |
0.052
|
|
|
|
single organism nuclear import
|
GO:1902593 |
104 |
0.052
|
|
|
|
regulation of cell growth
|
GO:0001558 |
135 |
0.052
|
Mouse |
|
|
regulation of response to external stimulus
|
GO:0032101 |
222 |
0.052
|
|
|
|
blastoderm segmentation
|
GO:0007350 |
2 |
0.051
|
|
|
|
positive regulation of cytoplasmic transport
|
GO:1903651 |
82 |
0.051
|
|
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
0.051
|
|
|
|
epithelium migration
|
GO:0090132 |
119 |
0.051
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
150 |
0.051
|
|
|
|
cellular response to hormone stimulus
|
GO:0032870 |
125 |
0.051
|
|
|
|
craniofacial suture morphogenesis
|
GO:0097094 |
3 |
0.050
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.050
|
|
|
|
regulation of jnk cascade
|
GO:0046328 |
73 |
0.050
|
|
|
|
regulation of mapk cascade
|
GO:0043408 |
262 |
0.050
|
|
|
|
sleep
|
GO:0030431 |
2 |
0.049
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.049
|
Mouse |
|
|
neurological system process
|
GO:0050877 |
163 |
0.049
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.049
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.048
|
Zebrafish |
|
|
cellular chemical homeostasis
|
GO:0055082 |
180 |
0.048
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.048
|
|
|
|
negative regulation of proteolysis
|
GO:0045861 |
132 |
0.048
|
|
|
|
gtp metabolic process
|
GO:0046039 |
239 |
0.048
|
|
|
|
rhythmic process
|
GO:0048511 |
31 |
0.047
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.046
|
|
|
|
oocyte maturation
|
GO:0001556 |
1 |
0.045
|
|
|
|
circadian sleep wake cycle
|
GO:0042745 |
2 |
0.044
|
|
|
|
positive regulation of growth
|
GO:0045927 |
58 |
0.044
|
Mouse |
|
|
memory
|
GO:0007613 |
3 |
0.044
|
|
|
|
regulation of actin filament based process
|
GO:0032970 |
141 |
0.044
|
|
|
|
cytokine production
|
GO:0001816 |
247 |
0.044
|
|
|
|
transmembrane transport
|
GO:0055085 |
399 |
0.043
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.043
|
|
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.043
|
|
|
|
regulation of secretion
|
GO:0051046 |
194 |
0.042
|
|
|
|
head development
|
GO:0060322 |
108 |
0.042
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.042
|
|
|
|
positive regulation of peptidyl tyrosine phosphorylation
|
GO:0050731 |
85 |
0.042
|
|
|
|
regulation of cell junction assembly
|
GO:1901888 |
29 |
0.042
|
|
|
|
regulation of defense response
|
GO:0031347 |
154 |
0.042
|
|
|
|
morphogenesis of an epithelium
|
GO:0002009 |
60 |
0.041
|
Fly |
|
|
response to oxygen levels
|
GO:0070482 |
100 |
0.041
|
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.041
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.041
|
|
|
|
response to other organism
|
GO:0051707 |
261 |
0.041
|
Zebrafish |
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.041
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.041
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.041
|
|
|
|
regulation of circadian sleep wake cycle
|
GO:0042749 |
2 |
0.041
|
|
|
|
actin filament based movement
|
GO:0030048 |
17 |
0.041
|
|
|
|
vasculature development
|
GO:0001944 |
181 |
0.041
|
|
|
|
positive regulation of intracellular protein transport
|
GO:0090316 |
76 |
0.041
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.041
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.040
|
|
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
79 |
0.040
|
|
|
|
positive regulation of nucleocytoplasmic transport
|
GO:0046824 |
54 |
0.040
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.039
|
|
|
|
regulation of stress activated protein kinase signaling cascade
|
GO:0070302 |
85 |
0.039
|
|
|
|
canonical wnt signaling pathway
|
GO:0060070 |
116 |
0.039
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.039
|
|
|
|
osteoblast differentiation
|
GO:0001649 |
92 |
0.039
|
|
|
|
positive regulation of cellular component movement
|
GO:0051272 |
181 |
0.039
|
|
|
|
secretion
|
GO:0046903 |
254 |
0.039
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.038
|
|
|
|
interleukin 6 production
|
GO:0032635 |
37 |
0.038
|
|
|
|
cellular response to nitrogen compound
|
GO:1901699 |
144 |
0.037
|
|
|
|
sensory perception of pain
|
GO:0019233 |
4 |
0.037
|
|
|
|
negative regulation of endopeptidase activity
|
GO:0010951 |
84 |
0.037
|
|
|
|
actin filament polymerization
|
GO:0030041 |
45 |
0.037
|
|
|
|
negative regulation of protein maturation
|
GO:1903318 |
142 |
0.036
|
|
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.036
|
Fly |
|
|
circadian sleep wake cycle sleep
|
GO:0050802 |
2 |
0.036
|
|
|
|
activation of protein kinase activity
|
GO:0032147 |
90 |
0.036
|
|
|
|
regulation of cell shape
|
GO:0008360 |
48 |
0.036
|
|
|
|
circadian sleep wake cycle process
|
GO:0022410 |
2 |
0.036
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.036
|
|
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.036
|
|
|
|
neuron projection morphogenesis
|
GO:0048812 |
50 |
0.036
|
Mouse Fly |
|
|
cell growth
|
GO:0016049 |
160 |
0.036
|
Mouse |
|
|
growth
|
GO:0040007 |
202 |
0.036
|
Mouse Fly |
|
|
immune system development
|
GO:0002520 |
195 |
0.036
|
|
|
|
regulation of neurogenesis
|
GO:0050767 |
82 |
0.036
|
Mouse Fly |
|
|
negative regulation of organelle organization
|
GO:0010639 |
126 |
0.036
|
|
|
|
spermatid differentiation
|
GO:0048515 |
4 |
0.035
|
|
|
|
regulation of adherens junction organization
|
GO:1903391 |
21 |
0.035
|
|
|
|
negative regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043154 |
46 |
0.035
|
|
|
|
regulation of protein complex assembly
|
GO:0043254 |
147 |
0.034
|
|
|
|
positive regulation of immune response
|
GO:0050778 |
159 |
0.034
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.034
|
|
|
|
cell matrix adhesion
|
GO:0007160 |
85 |
0.034
|
|
|
|
spermatid development
|
GO:0007286 |
4 |
0.034
|
|
|
|
positive regulation of cell size
|
GO:0045793 |
3 |
0.034
|
|
|
|
actin polymerization or depolymerization
|
GO:0008154 |
56 |
0.034
|
|
|
|
cation transport
|
GO:0006812 |
331 |
0.034
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.034
|
|
|
|
innate immune response
|
GO:0045087 |
178 |
0.034
|
|
|
|
response to decreased oxygen levels
|
GO:0036293 |
96 |
0.033
|
|
|
|
blood vessel morphogenesis
|
GO:0048514 |
162 |
0.033
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.033
|
|
|
|
single organismal cell cell adhesion
|
GO:0016337 |
148 |
0.033
|
|
|
|
transforming growth factor beta receptor signaling pathway
|
GO:0007179 |
76 |
0.033
|
|
|
|
regulation of synaptic plasticity
|
GO:0048167 |
3 |
0.033
|
|
|
|
connective tissue development
|
GO:0061448 |
39 |
0.033
|
|
|
|
organelle inheritance
|
GO:0048308 |
2 |
0.033
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.033
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
128 |
0.033
|
|
|
|
cell substrate adhesion
|
GO:0031589 |
132 |
0.033
|
|
|
|
calcium ion transport
|
GO:0006816 |
147 |
0.032
|
|
|
|
sensory perception
|
GO:0007600 |
103 |
0.032
|
|
|
|
ion transmembrane transport
|
GO:0034220 |
338 |
0.032
|
|
|
|
central nervous system development
|
GO:0007417 |
123 |
0.032
|
|
|
|
establishment of cell polarity
|
GO:0030010 |
22 |
0.032
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.032
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.032
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.031
|
|
|
|
stress activated protein kinase signaling cascade
|
GO:0031098 |
94 |
0.031
|
|
|
|
taxis
|
GO:0042330 |
157 |
0.031
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.031
|
|
|
|
neurotransmitter secretion
|
GO:0007269 |
4 |
0.031
|
|
|
|
histone modification
|
GO:0016570 |
251 |
0.031
|
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
130 |
0.031
|
|
|
|
negative regulation of catabolic process
|
GO:0009895 |
104 |
0.031
|
|
|
|
negative regulation of gliogenesis
|
GO:0014014 |
3 |
0.031
|
|
|
|
peripheral nervous system development
|
GO:0007422 |
2 |
0.031
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.030
|
|
|
|
negative regulation of smoothened signaling pathway
|
GO:0045879 |
3 |
0.030
|
|
|
|
tissue migration
|
GO:0090130 |
119 |
0.030
|
|
|
|
hindbrain development
|
GO:0030902 |
3 |
0.030
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
182 |
0.030
|
|
|
|
dendritic spine morphogenesis
|
GO:0060997 |
3 |
0.030
|
|
|
|
stem cell differentiation
|
GO:0048863 |
93 |
0.030
|
|
|
|
positive regulation of protein serine threonine kinase activity
|
GO:0071902 |
119 |
0.030
|
|
|
|
desensitization of g protein coupled receptor protein signaling pathway by arrestin
|
GO:0002032 |
2 |
0.030
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.030
|
|
|
|
positive regulation of locomotion
|
GO:0040017 |
186 |
0.030
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.030
|
|
|
|
regulation of protein localization to nucleus
|
GO:1900180 |
85 |
0.029
|
|
|
|
cellular component disassembly
|
GO:0022411 |
92 |
0.029
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.029
|
|
|
|
cerebellum development
|
GO:0021549 |
2 |
0.029
|
|
|
|
positive regulation of cell development
|
GO:0010720 |
92 |
0.029
|
Mouse |
|
|
regulation of protein targeting
|
GO:1903533 |
91 |
0.029
|
|
|
|
pattern recognition receptor signaling pathway
|
GO:0002221 |
48 |
0.029
|
|
|
|
angiogenesis
|
GO:0001525 |
147 |
0.029
|
|
|
|
oxidation reduction process
|
GO:0055114 |
396 |
0.029
|
|
|
|
cell projection assembly
|
GO:0030031 |
126 |
0.028
|
|
|
|
cation transmembrane transport
|
GO:0098655 |
238 |
0.028
|
|
|
|
regulation of actin cytoskeleton organization
|
GO:0032956 |
116 |
0.028
|
|
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.028
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.028
|
|
|
|
response to virus
|
GO:0009615 |
126 |
0.028
|
|
|
|
regulation of epithelial cell differentiation involved in kidney development
|
GO:2000696 |
4 |
0.028
|
|
|
|
negative regulation of cellular component movement
|
GO:0051271 |
106 |
0.028
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.028
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.028
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.028
|
|
|
|
negative regulation of cell size
|
GO:0045792 |
3 |
0.028
|
|
|
|
metencephalon development
|
GO:0022037 |
2 |
0.028
|
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
176 |
0.028
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.028
|
|
|
|
regulation of small gtpase mediated signal transduction
|
GO:0051056 |
156 |
0.028
|
|
|
|
positive regulation of cell motility
|
GO:2000147 |
177 |
0.027
|
|
|
|
positive regulation of cell migration
|
GO:0030335 |
172 |
0.027
|
|
|
|
organelle assembly
|
GO:0070925 |
176 |
0.027
|
|
|
|
nuclear division
|
GO:0000280 |
128 |
0.027
|
|
|
|
regulation of oocyte development
|
GO:0060281 |
1 |
0.027
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.027
|
|
|
|
epithelial cell differentiation
|
GO:0030855 |
141 |
0.027
|
Fly |
|
|
dephosphorylation
|
GO:0016311 |
209 |
0.027
|
|
|
|
neural tube closure
|
GO:0001843 |
3 |
0.027
|
|
|
|
motor neuron axon guidance
|
GO:0008045 |
2 |
0.027
|
|
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.027
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
303 |
0.027
|
|
|
|
tube closure
|
GO:0060606 |
3 |
0.027
|
|
|
|
regulation of tumor necrosis factor superfamily cytokine production
|
GO:1903555 |
44 |
0.027
|
|
|
|
regulation of ion transport
|
GO:0043269 |
189 |
0.027
|
|
|
|
reproductive process
|
GO:0022414 |
106 |
0.027
|
|
|
|
embryonic placenta development
|
GO:0001892 |
1 |
0.026
|
|
|
|
cell aggregation
|
GO:0098743 |
1 |
0.026
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.026
|
|
|
|
regulation of chromosome organization
|
GO:0033044 |
103 |
0.026
|
|
|
|
negative regulation of wnt signaling pathway
|
GO:0030178 |
69 |
0.026
|
|
|
|
g1 s transition of mitotic cell cycle
|
GO:0000082 |
78 |
0.026
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.026
|
|
|
|
peptidyl tyrosine phosphorylation
|
GO:0018108 |
170 |
0.026
|
|
|
|
negative regulation of protein kinase activity
|
GO:0006469 |
98 |
0.026
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.026
|
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
117 |
0.026
|
|
|
|
peptidyl lysine modification
|
GO:0018205 |
144 |
0.026
|
|
|
|
stem cell development
|
GO:0048864 |
69 |
0.026
|
|
|
|
regulation of cell substrate adhesion
|
GO:0010810 |
68 |
0.026
|
|
|
|
cell cycle checkpoint
|
GO:0000075 |
117 |
0.026
|
|
|
|
protein import into nucleus
|
GO:0006606 |
104 |
0.025
|
|
|
|
morphogenesis of a branching structure
|
GO:0001763 |
21 |
0.025
|
|
|
|
regulation of protein import into nucleus
|
GO:0042306 |
78 |
0.025
|
|
|
|
extrinsic apoptotic signaling pathway
|
GO:0097191 |
119 |
0.025
|
|
|
|
positive regulation of protein localization to nucleus
|
GO:1900182 |
48 |
0.025
|
|
|
|
intracellular receptor signaling pathway
|
GO:0030522 |
104 |
0.025
|
|
|
|
rna stabilization
|
GO:0043489 |
18 |
0.025
|
|
|
|
regulation of focal adhesion assembly
|
GO:0051893 |
20 |
0.025
|
|
|
|
regulation of neurotransmitter secretion
|
GO:0046928 |
3 |
0.025
|
|
|
|
inorganic ion transmembrane transport
|
GO:0098660 |
231 |
0.025
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
140 |
0.025
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.025
|
|
|
|
regulation of circadian sleep wake cycle sleep
|
GO:0045187 |
2 |
0.024
|
|
|
|
activation of innate immune response
|
GO:0002218 |
55 |
0.024
|
|
|
|
negative regulation of nervous system development
|
GO:0051961 |
28 |
0.024
|
|
|
|
branching morphogenesis of an epithelial tube
|
GO:0048754 |
19 |
0.024
|
|
|
|
positive regulation of transferase activity
|
GO:0051347 |
227 |
0.024
|
|
|
|
nuclear import
|
GO:0051170 |
106 |
0.024
|
|
|
|
skeletal system development
|
GO:0001501 |
79 |
0.024
|
|
|
|
response to cytokine
|
GO:0034097 |
232 |
0.024
|
|
|
|
positive regulation of cell adhesion
|
GO:0045785 |
84 |
0.024
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.024
|
|
|
|
positive regulation of sequence specific dna binding transcription factor activity
|
GO:0051091 |
131 |
0.024
|
|
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.023
|
|
|
|
semaphorin plexin signaling pathway
|
GO:0071526 |
4 |
0.023
|
|
|
|
organelle fission
|
GO:0048285 |
149 |
0.023
|
|
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
117 |
0.023
|
|
|
|
cellular senescence
|
GO:0090398 |
34 |
0.023
|
|
|
|
positive regulation of ion transport
|
GO:0043270 |
87 |
0.023
|
|
|
|
regulation of proteasomal protein catabolic process
|
GO:0061136 |
87 |
0.023
|
|
|
|
inorganic cation transmembrane transport
|
GO:0098662 |
194 |
0.023
|
|
|
|
cellular response to vascular endothelial growth factor stimulus
|
GO:0035924 |
26 |
0.023
|
|
|
|
cell morphogenesis involved in neuron differentiation
|
GO:0048667 |
44 |
0.023
|
Mouse Fly |
|
|
membrane organization
|
GO:0061024 |
292 |
0.023
|
|
|
|
peptidyl threonine modification
|
GO:0018210 |
45 |
0.023
|
|
|
|
regulation of actin filament length
|
GO:0030832 |
56 |
0.023
|
|
|
|
formation of primary germ layer
|
GO:0001704 |
42 |
0.023
|
|
|
|
rho protein signal transduction
|
GO:0007266 |
26 |
0.023
|
|
|
|
stress activated mapk cascade
|
GO:0051403 |
93 |
0.023
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
97 |
0.023
|
|
|
|
chromosome segregation
|
GO:0007059 |
114 |
0.023
|
|
|
|
axonogenesis
|
GO:0007409 |
31 |
0.023
|
Mouse Fly |
|
|
cell substrate junction assembly
|
GO:0007044 |
35 |
0.023
|
|
|
|
negative regulation of transferase activity
|
GO:0051348 |
124 |
0.022
|
|
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.022
|
|
|
|
reproductive system development
|
GO:0061458 |
56 |
0.022
|
|
|
|
retina layer formation
|
GO:0010842 |
3 |
0.022
|
|
|
|
dna integrity checkpoint
|
GO:0031570 |
71 |
0.022
|
|
|
|
neural tube patterning
|
GO:0021532 |
2 |
0.022
|
|
|
|
chromatin organization
|
GO:0006325 |
351 |
0.022
|
|
|
|
heart process
|
GO:0003015 |
62 |
0.022
|
|
|
|
cell activation
|
GO:0001775 |
213 |
0.022
|
|
|
|
single organism reproductive process
|
GO:0044702 |
98 |
0.022
|
|
|
|
syncytium formation by plasma membrane fusion
|
GO:0000768 |
2 |
0.022
|
|
|
|
positive regulation of peptidase activity
|
GO:0010952 |
88 |
0.022
|
|
|
|
regulation of axon guidance
|
GO:1902667 |
3 |
0.021
|
|
|
|
wound healing
|
GO:0042060 |
115 |
0.021
|
|
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
127 |
0.021
|
|
|
|
actin mediated cell contraction
|
GO:0070252 |
12 |
0.021
|
|
|
|
coagulation
|
GO:0050817 |
78 |
0.021
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.021
|
|
|
|
regulation of binding
|
GO:0051098 |
111 |
0.021
|
|
|
|
positive regulation of innate immune response
|
GO:0045089 |
79 |
0.021
|
|
|
|
response to lipid
|
GO:0033993 |
206 |
0.021
|
|
|
|
calcium ion transmembrane transport
|
GO:0070588 |
76 |
0.021
|
|
|
|
positive regulation of defense response
|
GO:0031349 |
87 |
0.021
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
177 |
0.021
|
|
|
|
trachea development
|
GO:0060438 |
1 |
0.021
|
|
|
|
hematopoietic or lymphoid organ development
|
GO:0048534 |
186 |
0.021
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.021
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.021
|
|
|
|
positive regulation of cell differentiation
|
GO:0045597 |
211 |
0.021
|
Mouse |
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.021
|
|
|
|
heart development
|
GO:0007507 |
95 |
0.021
|
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
166 |
0.021
|
|
|
|
cell division
|
GO:0051301 |
168 |
0.021
|
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.020
|
|
|
|
response to salt stress
|
GO:0009651 |
3 |
0.020
|
|
|
|
regulation of synaptic transmission dopaminergic
|
GO:0032225 |
4 |
0.020
|
|
|
|
regulation of peptidyl tyrosine phosphorylation
|
GO:0050730 |
108 |
0.020
|
|
|
|
axon development
|
GO:0061564 |
34 |
0.020
|
Mouse Fly |
|
|
reproductive structure development
|
GO:0048608 |
55 |
0.020
|
|
|
|
convergent extension
|
GO:0060026 |
1 |
0.020
|
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
116 |
0.020
|
|
|
|
jnk cascade
|
GO:0007254 |
80 |
0.020
|
|
|
|
regulation of map kinase activity
|
GO:0043405 |
108 |
0.020
|
|
