Homo sapiens

279 known processes

NTRK1

neurotrophic tyrosine kinase, receptor, type 1

(Aliases: TRK,DKFZp781I14186,TRKA,p140-TrkA,Trk-A,TRK1,MTC)

NTRK1 biological process predictions


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Biological process GO term ID Process size Probability Func Analog Org
positive regulation of map kinase activity GO:0043406 80 0.977
Human
activation of mapk activity GO:0000187 45 0.957
Human
regulation of map kinase activity GO:0043405 108 0.906
Human
regulation of protein serine threonine kinase activity GO:0071900 179 0.902
Human
positive regulation of mapk cascade GO:0043410 190 0.902
regulation of cell motility GO:2000145 299 0.897
Human
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.896
peptidyl tyrosine modification GO:0018212 170 0.895
regulation of cellular amine metabolic process GO:0033238 11 0.874
activation of protein kinase b activity GO:0032148 14 0.845
Human
positive regulation of cellular amine metabolic process GO:0033240 7 0.817
positive regulation of protein phosphorylation GO:0001934 313 0.765
Human
regulation of kinase activity GO:0043549 314 0.755
Human
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.749
cellular response to endogenous stimulus GO:0071495 336 0.741
positive regulation of cell motility GO:2000147 177 0.725
Human
cellular ketone metabolic process GO:0042180 80 0.701
sensory perception of pain GO:0019233 4 0.701
Rat
regulation of cell migration GO:0030334 289 0.680
Human
activation of protein kinase activity GO:0032147 90 0.672
Human
peptidyl serine phosphorylation GO:0018105 101 0.648
Human
mapk cascade GO:0000165 288 0.629
positive regulation of cell differentiation GO:0045597 211 0.629
positive regulation of protein serine threonine kinase activity GO:0071902 119 0.619
Human
signal transduction by phosphorylation GO:0023014 297 0.614
peripheral nervous system development GO:0007422 2 0.612
regulation of locomotion GO:0040012 329 0.609
Human
glycosyl compound catabolic process GO:1901658 413 0.592
positive regulation of collateral sprouting GO:0048672 2 0.583
protein autophosphorylation GO:0046777 123 0.583
calcium ion homeostasis GO:0055074 122 0.576
nerve development GO:0021675 4 0.568
Mouse Rat
collateral sprouting GO:0048668 2 0.552
positive regulation of cell development GO:0010720 92 0.551
positive regulation of phosphorylation GO:0042327 394 0.550
positive regulation of cell proliferation GO:0008284 301 0.539
Human
positive regulation of cytosolic calcium ion concentration GO:0007204 82 0.534
peptidyl serine modification GO:0018209 106 0.531
Human
positive regulation of protein kinase activity GO:0045860 190 0.526
Human
regulation of peptidyl tyrosine phosphorylation GO:0050730 108 0.516
positive regulation of locomotion GO:0040017 186 0.514
Human
negative regulation of cell death GO:0060548 345 0.509
Mouse Rat
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.505
positive regulation of developmental process GO:0051094 314 0.505
cellular amine metabolic process GO:0044106 41 0.498
amine metabolic process GO:0009308 44 0.492
cell type specific apoptotic process GO:0097285 125 0.489
Mouse Rat
negative regulation of apoptotic process GO:0043066 316 0.487
Mouse Rat
positive regulation of neurogenesis GO:0050769 49 0.482
positive regulation of cellular component movement GO:0051272 181 0.475
Human
positive regulation of ras gtpase activity GO:0032320 117 0.472
actin filament based process GO:0030029 224 0.472
Human
regulation of ras gtpase activity GO:0032318 128 0.472
small gtpase mediated signal transduction GO:0007264 78 0.461
cell development GO:0048468 328 0.450
positive regulation of axon extension GO:0045773 4 0.443
nucleoside phosphate catabolic process GO:1901292 412 0.431
neurotransmitter secretion GO:0007269 4 0.412
neuron projection development GO:0031175 106 0.397
peptidyl tyrosine phosphorylation GO:0018108 170 0.393
regulation of gtpase activity GO:0043087 180 0.382
cytoplasmic transport GO:0016482 379 0.377
cytosolic calcium ion homeostasis GO:0051480 89 0.368
enzyme linked receptor protein signaling pathway GO:0007167 303 0.368
regulation of neuron differentiation GO:0045664 70 0.363
regulation of cell differentiation GO:0045595 393 0.356
regulation of gtp catabolic process GO:0033124 180 0.337
organophosphate catabolic process GO:0046434 430 0.335
ras protein signal transduction GO:0007265 73 0.331
ion homeostasis GO:0050801 230 0.326
positive regulation of kinase activity GO:0033674 204 0.326
Human
positive regulation of neuron differentiation GO:0045666 40 0.325
cation homeostasis GO:0055080 189 0.311
nervous system development GO:0007399 293 0.311
cellular response to nerve growth factor stimulus GO:1990090 6 0.305
nerve growth factor signaling pathway GO:0038180 4 0.303
cellular divalent inorganic cation homeostasis GO:0072503 128 0.301
cellular cation homeostasis GO:0030003 163 0.301
regulation of erk1 and erk2 cascade GO:0070372 99 0.298
regulation of cardiac muscle cell apoptotic process GO:0010665 3 0.298
cellular amino acid metabolic process GO:0006520 116 0.294
secretion by cell GO:0032940 226 0.293
nucleotide catabolic process GO:0009166 408 0.290
regulation of ras protein signal transduction GO:0046578 155 0.290
positive regulation of peptidyl serine phosphorylation GO:0033138 42 0.290
Human
chemical homeostasis GO:0048878 306 0.288
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 85 0.288
positive regulation of cellular component organization GO:0051130 376 0.287
regulation of mapk cascade GO:0043408 262 0.287
secretion GO:0046903 254 0.282
regulation of reactive oxygen species metabolic process GO:2000377 41 0.280
regulation of cellular component movement GO:0051270 334 0.270
Human
regulation of cell development GO:0060284 161 0.264
cellular calcium ion homeostasis GO:0006874 117 0.261
positive regulation of erk1 and erk2 cascade GO:0070374 75 0.258
neural crest cell development GO:0014032 3 0.253
signal transduction in absence of ligand GO:0038034 22 0.247
positive regulation of neuron projection development GO:0010976 34 0.247
positive regulation of cellular catabolic process GO:0031331 284 0.245
regulation of neuron projection development GO:0010975 57 0.242
purine nucleotide catabolic process GO:0006195 405 0.236
purine ribonucleoside metabolic process GO:0046128 437 0.236
cell projection organization GO:0030030 252 0.235
guanosine containing compound metabolic process GO:1901068 244 0.233
regulation of transferase activity GO:0051338 355 0.230
Human
positive regulation of cell projection organization GO:0031346 64 0.230
metal ion homeostasis GO:0055065 169 0.228
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.227
regulation of purine nucleotide catabolic process GO:0033121 205 0.225
regulation of neurogenesis GO:0050767 82 0.225
regulation of calcium ion transport into cytosol GO:0010522 33 0.223
cell cell signaling GO:0007267 155 0.223
Rat
cellular ion homeostasis GO:0006873 168 0.223
regulation of reactive oxygen species biosynthetic process GO:1903426 3 0.216
regulation of cell maturation GO:1903429 3 0.215
positive regulation of transport GO:0051050 336 0.214
regulation of cellular ketone metabolic process GO:0010565 50 0.212
negative regulation of programmed cell death GO:0043069 321 0.211
Mouse Rat
extrinsic apoptotic signaling pathway GO:0097191 119 0.208
reactive nitrogen species metabolic process GO:2001057 3 0.207
cell morphogenesis involved in differentiation GO:0000904 144 0.206
Mouse Rat Worm
regulation of homeostatic process GO:0032844 121 0.205
divalent inorganic cation homeostasis GO:0072507 136 0.204
purine nucleoside triphosphate catabolic process GO:0009146 392 0.204
regulation of secretion by cell GO:1903530 177 0.202
positive regulation of response to external stimulus GO:0032103 88 0.200
Human
regulation of cell morphogenesis GO:0022604 153 0.198
positive regulation of reactive oxygen species biosynthetic process GO:1903428 2 0.196
neuron differentiation GO:0030182 138 0.193
nucleoside triphosphate metabolic process GO:0009141 422 0.193
positive regulation of organelle organization GO:0010638 195 0.192
Human
regulation of cellular amino acid metabolic process GO:0006521 6 0.190
regulation of intracellular transport GO:0032386 195 0.188
reactive oxygen species biosynthetic process GO:1903409 4 0.187
divalent metal ion transport GO:0070838 152 0.185
system process GO:0003008 349 0.184
Rat
positive regulation of dna metabolic process GO:0051054 73 0.183
regulation of actin filament based process GO:0032970 141 0.183
Human
cellular response to oxygen containing compound GO:1901701 276 0.182
regulation of peptidyl serine phosphorylation GO:0033135 50 0.179
Human
apoptotic signaling pathway GO:0097190 268 0.175
intracellular protein transport GO:0006886 270 0.175
neuron apoptotic process GO:0051402 39 0.174
Mouse Rat
regeneration GO:0031099 4 0.173
cell growth GO:0016049 160 0.173
regulation of protein kinase activity GO:0045859 289 0.170
Human
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.170
positive regulation of gtpase activity GO:0043547 166 0.169
positive regulation of nucleoside metabolic process GO:0045979 186 0.169
negative regulation of protein metabolic process GO:0051248 391 0.168
Human
cellular metal ion homeostasis GO:0006875 146 0.166
regulation of cellular component biogenesis GO:0044087 281 0.164
jnk cascade GO:0007254 80 0.161
cellular homeostasis GO:0019725 196 0.161
positive regulation of catabolic process GO:0009896 310 0.160
ribonucleotide catabolic process GO:0009261 405 0.157
sequestering of metal ion GO:0051238 24 0.155
vesicle mediated transport GO:0016192 371 0.153
regulation of response to external stimulus GO:0032101 222 0.153
Human
positive regulation of cell growth GO:0030307 48 0.152
regulation of anatomical structure size GO:0090066 101 0.151
organ morphogenesis GO:0009887 147 0.150
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.149
cytosolic calcium ion transport GO:0060401 48 0.148
behavior GO:0007610 112 0.146
Human Rat
cellular response to dna damage stimulus GO:0006974 379 0.146
positive regulation of positive chemotaxis GO:0050927 13 0.144
Human
regulation of jnk cascade GO:0046328 73 0.143
regulation of nervous system development GO:0051960 88 0.142
cellular chemical homeostasis GO:0055082 180 0.142
second messenger mediated signaling GO:0019932 78 0.138
positive regulation of cell death GO:0010942 263 0.138
Rat
chemotaxis GO:0006935 157 0.138
Human Rat Worm
regulation of anatomical structure morphogenesis GO:0022603 286 0.138
neurological system process GO:0050877 163 0.137
Rat
regulation of cell morphogenesis involved in differentiation GO:0010769 83 0.137
growth GO:0040007 202 0.137
male genitalia development GO:0030539 1 0.136
negative regulation of phosphorylation GO:0042326 174 0.136
Human
cell morphogenesis GO:0000902 296 0.135
Mouse Rat Worm
regulation of secretion GO:0051046 194 0.134
positive regulation of transferase activity GO:0051347 227 0.133
Human
positive regulation of nucleotide catabolic process GO:0030813 185 0.133
regulation of actin cytoskeleton organization GO:0032956 116 0.132
Human
neural crest cell migration GO:0001755 2 0.130
ribonucleoside triphosphate catabolic process GO:0009203 391 0.129
positive regulation of tyrosine phosphorylation of stat5 protein GO:0042523 11 0.129
positive regulation of epithelial cell proliferation GO:0050679 65 0.128
positive chemotaxis GO:0050918 33 0.128
Human
gtp metabolic process GO:0046039 239 0.123
myeloid cell differentiation GO:0030099 117 0.122
negative regulation of multicellular organismal process GO:0051241 317 0.121
regulation of protein localization GO:0032880 296 0.121
negative regulation of cell differentiation GO:0045596 171 0.120
reactive oxygen species metabolic process GO:0072593 75 0.120
developmental cell growth GO:0048588 18 0.120
leukocyte differentiation GO:0002521 98 0.119
Mouse
regulation of chemotaxis GO:0050920 74 0.117
Human
circulatory system development GO:0072359 262 0.117
regulation of cell growth GO:0001558 135 0.116
single organism cellular localization GO:1902580 332 0.116
negative regulation of peptidyl tyrosine phosphorylation GO:0050732 20 0.115
positive regulation of protein kinase b signaling GO:0051897 42 0.114
positive regulation of reactive oxygen species metabolic process GO:2000379 24 0.114
positive regulation of hydrolase activity GO:0051345 331 0.113
cell part morphogenesis GO:0032990 137 0.113
Mouse Rat Worm
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.113
tissue regeneration GO:0042246 3 0.112
sequestering of calcium ion GO:0051208 17 0.111
lipid metabolic process GO:0006629 381 0.111
skeletal system morphogenesis GO:0048705 24 0.111
response to hormone GO:0009725 175 0.111
negative regulation of phosphorus metabolic process GO:0010563 267 0.111
Human
regulation of small gtpase mediated signal transduction GO:0051056 156 0.110
regulation of protein transport GO:0051223 213 0.108
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.107
regulation of cellular response to stress GO:0080135 244 0.107
regulation of cell cycle process GO:0010564 266 0.106
calcium ion transport GO:0006816 147 0.105
developmental growth involved in morphogenesis GO:0060560 23 0.103
nucleoside triphosphate catabolic process GO:0009143 394 0.103
cellular response to growth factor stimulus GO:0071363 197 0.101
neurogenesis GO:0022008 169 0.100
regulation of calcium ion transport GO:0051924 79 0.100
tube development GO:0035295 125 0.099
phosphatidylinositol mediated signaling GO:0048015 55 0.099
regulation of behavior GO:0050795 82 0.098
Human
regulation of cell cycle GO:0051726 393 0.098
regulation of dna metabolic process GO:0051052 153 0.097
negative regulation of neuron apoptotic process GO:0043524 23 0.096
Mouse Rat
actin cytoskeleton organization GO:0030036 207 0.096
Human
forebrain neuron differentiation GO:0021879 3 0.095
regulation of cytoskeleton organization GO:0051493 177 0.093
Human
cellular response to lipid GO:0071396 127 0.093
regulation of neuron death GO:1901214 56 0.093
Mouse Rat
response to organic cyclic compound GO:0014070 204 0.092
Rat
response to nerve growth factor GO:1990089 6 0.090
purine ribonucleotide catabolic process GO:0009154 404 0.089
regulation of cytoplasmic transport GO:1903649 149 0.089
endothelial cell migration GO:0043542 86 0.089
regulation of cell projection organization GO:0031344 107 0.089
regulation of mitotic cell cycle GO:0007346 189 0.088
cellular response to hormone stimulus GO:0032870 125 0.087
regulation of glucose import GO:0046324 21 0.087
regulation of nucleotide metabolic process GO:0006140 269 0.086
ribonucleoside triphosphate metabolic process GO:0009199 412 0.086
dna replication GO:0006260 116 0.085
negative regulation of developmental process GO:0051093 247 0.083
purine nucleoside catabolic process GO:0006152 398 0.083
organ formation GO:0048645 3 0.081
response to growth factor GO:0070848 205 0.081
positive regulation of protein transport GO:0051222 135 0.080
motor neuron axon guidance GO:0008045 2 0.080
positive regulation of programmed cell death GO:0043068 249 0.079
Rat
negative regulation of neuron death GO:1901215 32 0.079
Mouse Rat
anatomical structure formation involved in morphogenesis GO:0048646 284 0.078
purine ribonucleoside catabolic process GO:0046130 398 0.077
erk1 and erk2 cascade GO:0070371 104 0.077
nucleocytoplasmic transport GO:0006913 176 0.077
segmentation GO:0035282 4 0.077
positive regulation of jak stat cascade GO:0046427 35 0.076
hemopoiesis GO:0030097 180 0.075
Mouse
tor signaling GO:0031929 39 0.074
taxis GO:0042330 157 0.074
Human Rat Worm
purine nucleoside triphosphate metabolic process GO:0009144 412 0.073
regulation of metal ion transport GO:0010959 120 0.073
positive regulation of cell morphogenesis involved in differentiation GO:0010770 50 0.072
striated muscle cell apoptotic process GO:0010658 3 0.071
myeloid leukocyte differentiation GO:0002573 60 0.071
regulation of extent of cell growth GO:0061387 9 0.071
post embryonic development GO:0009791 2 0.069
response to oxidative stress GO:0006979 121 0.069
regulation of epithelial cell proliferation GO:0050678 113 0.069
tyrosine phosphorylation of stat5 protein GO:0042506 13 0.069
mitotic cell cycle GO:0000278 326 0.069
divalent inorganic cation transport GO:0072511 158 0.069
inner ear morphogenesis GO:0042472 4 0.069
neuron development GO:0048666 113 0.068
stem cell division GO:0017145 2 0.067
Worm
negative regulation of cellular amine metabolic process GO:0033239 3 0.067
cellular component morphogenesis GO:0032989 314 0.067
Mouse Rat Worm
regulation of growth GO:0040008 165 0.067
regulation of cytokine production GO:0001817 232 0.067
hematopoietic or lymphoid organ development GO:0048534 186 0.067
Mouse
cellular response to nitrogen compound GO:1901699 144 0.066
Rat
female gamete generation GO:0007292 2 0.066
negative regulation of protein phosphorylation GO:0001933 140 0.065
Human
protein localization to nucleus GO:0034504 136 0.064
response to other organism GO:0051707 261 0.064
immune system development GO:0002520 195 0.063
Mouse
regulation of tyrosine phosphorylation of stat5 protein GO:0042522 12 0.063
forebrain generation of neurons GO:0021872 3 0.063
circadian behavior GO:0048512 2 0.063
positive regulation of endocytosis GO:0045807 42 0.062
regulation of immune response GO:0050776 201 0.062
neuron fate commitment GO:0048663 2 0.061
muscle tissue development GO:0060537 62 0.061
response to oxygen containing compound GO:1901700 369 0.060
Rat
rhythmic behavior GO:0007622 2 0.060
stress activated protein kinase signaling cascade GO:0031098 94 0.060
tissue migration GO:0090130 119 0.060
positive regulation of intracellular transport GO:0032388 104 0.059
skeletal system development GO:0001501 79 0.059
extrinsic apoptotic signaling pathway in absence of ligand GO:0097192 22 0.059
actin cytoskeleton reorganization GO:0031532 37 0.058
Human
regulation of ion homeostasis GO:2000021 73 0.058
regulation of cardiac muscle tissue growth GO:0055021 4 0.057
blastoderm segmentation GO:0007350 2 0.057
ameboidal type cell migration GO:0001667 135 0.057
spinal cord development GO:0021510 4 0.057
response to axon injury GO:0048678 1 0.057
Rat
response to lipid GO:0033993 206 0.057
carbohydrate transport GO:0008643 37 0.056
developmental growth GO:0048589 48 0.056
circadian rhythm GO:0007623 21 0.056
Mouse
cytokine production GO:0001816 247 0.055
negative regulation of cell proliferation GO:0008285 228 0.055
activation of ras gtpase activity GO:0032856 15 0.055
Human
compound eye development GO:0048749 1 0.055
regulation of stress activated mapk cascade GO:0032872 84 0.054
regulation of collateral sprouting GO:0048670 2 0.054
morphogenesis of an epithelium GO:0002009 60 0.053
endochondral bone morphogenesis GO:0060350 3 0.053
regulation of proteolysis GO:0030162 293 0.052
regulation of sequestering of calcium ion GO:0051282 41 0.051
neuron death GO:0070997 65 0.051
Mouse Rat
regulation of protein secretion GO:0050708 86 0.051
generation of neurons GO:0048699 152 0.050
regulation of stress activated protein kinase signaling cascade GO:0070302 85 0.050
positive regulation of nitric oxide synthase biosynthetic process GO:0051770 3 0.050
negative regulation of homeostatic process GO:0032845 59 0.050
positive regulation of endothelial cell migration GO:0010595 39 0.050
response to steroid hormone GO:0048545 80 0.050
neurotrophin signaling pathway GO:0038179 8 0.050
maintenance of location GO:0051235 112 0.049
cation transport GO:0006812 331 0.049
positive regulation of cell cycle GO:0045787 140 0.049
response to external biotic stimulus GO:0043207 261 0.048
metal ion transport GO:0030001 272 0.048
positive regulation of dna replication GO:0045740 35 0.048
leukocyte activation GO:0045321 164 0.048
Mouse
rna processing GO:0006396 255 0.048
mitotic cell cycle process GO:1903047 286 0.048
response to cytokine GO:0034097 232 0.048
negative regulation of sequestering of calcium ion GO:0051283 41 0.048
regulation of cardiac muscle cell proliferation GO:0060043 4 0.048
hindbrain development GO:0030902 3 0.047
positive regulation of cell migration GO:0030335 172 0.047
Human
positive regulation of gtp catabolic process GO:0033126 166 0.047
protein import into nucleus GO:0006606 104 0.047
cell morphogenesis involved in neuron differentiation GO:0048667 44 0.046
Mouse Rat Worm
protein targeting to nucleus GO:0044744 104 0.046
mating GO:0007618 1 0.046
response to biotic stimulus GO:0009607 276 0.046
single organism carbohydrate metabolic process GO:0044723 193 0.045
regulation of apoptotic signaling pathway GO:2001233 175 0.045
regulation of release of sequestered calcium ion into cytosol GO:0051279 27 0.045
protein processing GO:0016485 226 0.045
negative regulation of transcription from rna polymerase ii promoter GO:0000122 281 0.045
epithelial cell migration GO:0010631 119 0.045
lymphocyte homeostasis GO:0002260 4 0.044
somatic muscle development GO:0007525 1 0.044
positive regulation of developmental growth GO:0048639 16 0.044
negative regulation of intracellular signal transduction GO:1902532 183 0.044
organelle fission GO:0048285 149 0.044
negative regulation of protein modification process GO:0031400 200 0.044
Human
positive regulation of sequence specific dna binding transcription factor activity GO:0051091 131 0.043
regulation of ion transport GO:0043269 189 0.043
positive regulation of cytokine production GO:0001819 167 0.043
synaptic transmission GO:0007268 61 0.043
Rat
immune response GO:0006955 307 0.043
regulation of endothelial cell migration GO:0010594 67 0.043
protein targeting GO:0006605 187 0.042
response to abiotic stimulus GO:0009628 336 0.042
Rat
innate immune response GO:0045087 178 0.042
response to reactive oxygen species GO:0000302 61 0.041
positive regulation of cellular component biogenesis GO:0044089 158 0.041
regulation of endocytosis GO:0030100 72 0.041
regulation of heart contraction GO:0008016 50 0.041
neuron projection extension GO:1990138 14 0.041
anatomical structure homeostasis GO:0060249 100 0.041
glial cell migration GO:0008347 4 0.040
negative regulation of cellular component organization GO:0051129 235 0.040
interspecies interaction between organisms GO:0044419 156 0.040
cell fate determination GO:0001709 3 0.040
sex determination GO:0007530 3 0.040
muscle organ development GO:0007517 56 0.040
signal release GO:0023061 70 0.040
cell differentiation in spinal cord GO:0021515 1 0.039
negative regulation of axon extension GO:0030517 2 0.039
embryo development GO:0009790 123 0.039
cardiac muscle cell apoptotic process GO:0010659 3 0.039
cell projection morphogenesis GO:0048858 129 0.039
Mouse Rat Worm
dna repair GO:0006281 198 0.039
monosaccharide transport GO:0015749 32 0.039
positive regulation of apoptotic process GO:0043065 246 0.039
interleukin 12 mediated signaling pathway GO:0035722 3 0.039
cellular response to organic cyclic compound GO:0071407 127 0.039
Rat
regulation of intracellular protein transport GO:0033157 123 0.039
positive regulation of mast cell activation GO:0033005 2 0.039
regulation of establishment of protein localization GO:0070201 242 0.038
blood vessel morphogenesis GO:0048514 162 0.038
establishment or maintenance of bipolar cell polarity GO:0061245 2 0.038
developmental maturation GO:0021700 28 0.038
memory GO:0007613 3 0.038
heart development GO:0007507 95 0.038
multicellular organismal response to stress GO:0033555 1 0.038
regulation of peptidase activity GO:0052547 180 0.038
regulation of leukocyte differentiation GO:1902105 61 0.037
regulation of system process GO:0044057 101 0.037
morphogenesis of embryonic epithelium GO:0016331 4 0.037
positive regulation of tyrosine phosphorylation of stat protein GO:0042531 28 0.037
single organism nuclear import GO:1902593 104 0.037
cell cycle phase transition GO:0044770 173 0.036
positive regulation of nervous system development GO:0051962 54 0.036
heart process GO:0003015 62 0.036
negative regulation of feeding behavior GO:2000252 1 0.036
axon extension GO:0048675 13 0.036
regulation of ossification GO:0030278 58 0.036
determination of adult lifespan GO:0008340 2 0.035
establishment of protein localization to organelle GO:0072594 172 0.035
regulation of blood circulation GO:1903522 59 0.035
protein localization to organelle GO:0033365 280 0.035
regulation of protein catabolic process GO:0042176 155 0.035
cellular response to organonitrogen compound GO:0071417 124 0.034
Rat
positive regulation of mesenchymal cell proliferation GO:0002053 2 0.034
regulation of extrinsic apoptotic signaling pathway in absence of ligand GO:2001239 20 0.034
exocytosis GO:0006887 71 0.034
regulation of vesicle mediated transport GO:0060627 130 0.034
positive regulation of actin cytoskeleton reorganization GO:2000251 9 0.034
Human
nitric oxide biosynthetic process GO:0006809 20 0.034
vasculature development GO:0001944 181 0.034
positive regulation of proteolysis GO:0045862 142 0.034
locomotory behavior GO:0007626 1 0.033
regulation of defense response GO:0031347 154 0.033
mitochondrion organization GO:0007005 156 0.033
regulation of tor signaling GO:0032006 30 0.033
response to estrogen GO:0043627 47 0.033
tyrosine phosphorylation of stat protein GO:0007260 33 0.033
positive regulation of fibroblast proliferation GO:0048146 21 0.033
natural killer cell differentiation GO:0001779 2 0.033
positive regulation of cardiac muscle cell proliferation GO:0060045 2 0.033
inositol lipid mediated signaling GO:0048017 55 0.033
modulation by virus of host morphology or physiology GO:0019048 10 0.033
immune effector process GO:0002252 159 0.032
nuclear import GO:0051170 106 0.032
angiogenesis GO:0001525 147 0.032
positive regulation of homeostatic process GO:0032846 47 0.032
regulation of epithelial cell migration GO:0010632 93 0.032
regulation of myeloid leukocyte mediated immunity GO:0002886 4 0.032
cellular response to acid chemical GO:0071229 44 0.032
positive regulation of muscle cell apoptotic process GO:0010661 4 0.031
regulation of tyrosine phosphorylation of stat3 protein GO:0042516 18 0.031
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.031
negative regulation of gliogenesis GO:0014014 3 0.031
cellular lipid metabolic process GO:0044255 303 0.031
epithelial cell proliferation GO:0050673 128 0.030
carbohydrate derivative biosynthetic process GO:1901137 207 0.030
mast cell degranulation GO:0043303 4 0.030
regulation of striated muscle cell apoptotic process GO:0010662 3 0.030
positive regulation of secretion by cell GO:1903532 108 0.030
regulation of nucleoside metabolic process GO:0009118 209 0.030
calcium mediated signaling GO:0019722 44 0.030
positive regulation of apoptotic signaling pathway GO:2001235 70 0.029
humoral immune response GO:0006959 49 0.029
negative regulation of mapk cascade GO:0043409 56 0.029
lymphocyte activation GO:0046649 133 0.029
Mouse
small molecule biosynthetic process GO:0044283 157 0.029
protein heterotetramerization GO:0051290 3 0.029
regulation of protein targeting GO:1903533 91 0.029
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.029
regulation of cytokine secretion GO:0050707 57 0.029
cell division GO:0051301 168 0.029
Worm
negative regulation of cellular protein metabolic process GO:0032269 353 0.028
Human
organelle assembly GO:0070925 176 0.028
multi organism cellular process GO:0044764 156 0.028
photoreceptor cell differentiation GO:0046530 2 0.028
nuclear transport GO:0051169 179 0.028
neuron remodeling GO:0016322 2 0.028
cytokine secretion GO:0050663 64 0.028
mrna metabolic process GO:0016071 175 0.028

NTRK1 disease predictions

Disease DO term ID Size Probability Func Analog Org
nervous system disease DOID:863 431 0.175
neuropathy DOID:870 52 0.175
disease of cellular proliferation DOID:14566 174 0.080
peripheral neuropathy DOID:0060053 12 0.071
cancer DOID:162 167 0.071
immune system disease DOID:2914 155 0.047
organ system cancer DOID:0050686 164 0.043
hereditary sensory neuropathy DOID:0050548 12 0.037
hematopoietic system disease DOID:74 100 0.037
central nervous system disease DOID:331 186 0.036
kidney disease DOID:557 36 0.036
urinary system disease DOID:18 40 0.036