Homo sapiens

0 known processes

HLA-DQA2

major histocompatibility complex, class II, DQ alpha 2

(Aliases: HLA-DXA,DX-ALPHA)

HLA-DQA2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
dendritic cell antigen processing and presentation GO:0002468 1 0.155
immune response GO:0006955 307 0.112
innate immune response GO:0045087 178 0.106
positive regulation of immune system process GO:0002684 283 0.069
defense response GO:0006952 315 0.068
cell activation GO:0001775 213 0.064
cellular amine metabolic process GO:0044106 41 0.063
amine metabolic process GO:0009308 44 0.060
cytokine production GO:0001816 247 0.059
cellular amino acid metabolic process GO:0006520 116 0.058
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.058
positive regulation of cytokine production GO:0001819 167 0.057
regulation of immune response GO:0050776 201 0.054
regulation of defense response GO:0031347 154 0.053
regulation of cellular ketone metabolic process GO:0010565 50 0.050
inflammatory response to antigenic stimulus GO:0002437 4 0.050
leukocyte activation GO:0045321 164 0.050
post embryonic development GO:0009791 2 0.050
lymphocyte activation GO:0046649 133 0.048
protein maturation GO:0051604 233 0.048
regulation of cellular amino acid metabolic process GO:0006521 6 0.046
regulation of cell activation GO:0050865 125 0.046
positive regulation of cellular amine metabolic process GO:0033240 7 0.046
regulation of cellular amine metabolic process GO:0033238 11 0.045
positive regulation of transport GO:0051050 336 0.045
antigen processing and presentation GO:0019882 33 0.044
negative regulation of cell proliferation GO:0008285 228 0.044
cellular protein complex assembly GO:0043623 188 0.044
response to external biotic stimulus GO:0043207 261 0.042
regulation of establishment of protein localization GO:0070201 242 0.041
cellular macromolecular complex assembly GO:0034622 324 0.041
cellular ketone metabolic process GO:0042180 80 0.040
positive regulation of immune response GO:0050778 159 0.039
response to biotic stimulus GO:0009607 276 0.039
nitrogen compound transport GO:0071705 191 0.038
negative regulation of immune system process GO:0002683 136 0.037
regulation of cytokine production GO:0001817 232 0.037
secretion by cell GO:0032940 226 0.037
secretion GO:0046903 254 0.036
regulation of protein transport GO:0051223 213 0.035
response to bacterium GO:0009617 144 0.035
multicellular organismal aging GO:0010259 3 0.035
regulation of leukocyte activation GO:0002694 115 0.035
positive regulation of leukocyte activation GO:0002696 80 0.035
regulation of lymphocyte activation GO:0051249 103 0.035
cellular homeostasis GO:0019725 196 0.033
cellular response to oxygen containing compound GO:1901701 276 0.033
regulation of secretion GO:0051046 194 0.032
mononuclear cell proliferation GO:0032943 71 0.032
response to other organism GO:0051707 261 0.031
negative regulation of protein metabolic process GO:0051248 391 0.031
lymphocyte proliferation GO:0046651 70 0.031
regulation of interleukin 10 secretion GO:2001179 4 0.031
regulation of lymphocyte proliferation GO:0050670 64 0.031
regulation of mononuclear cell proliferation GO:0032944 65 0.030
positive regulation of cell activation GO:0050867 81 0.030
positive regulation of cell proliferation GO:0008284 301 0.030
positive regulation of lymphocyte activation GO:0051251 73 0.030
transmembrane transport GO:0055085 399 0.030
negative regulation of catalytic activity GO:0043086 335 0.030
determination of adult lifespan GO:0008340 2 0.029
system process GO:0003008 349 0.029
response to oxygen containing compound GO:1901700 369 0.029
regulation of protein localization GO:0032880 296 0.029
positive regulation of lymphocyte proliferation GO:0050671 46 0.028
purine nucleoside catabolic process GO:0006152 398 0.027
regulation of leukocyte proliferation GO:0070663 67 0.027
positive regulation of phosphorylation GO:0042327 394 0.027
lipid metabolic process GO:0006629 381 0.026
regulation of response to external stimulus GO:0032101 222 0.026
immune effector process GO:0002252 159 0.026
peptide transport GO:0015833 74 0.026
positive regulation of protein kinase activity GO:0045860 190 0.025
protein oligomerization GO:0051259 173 0.025
glycosyl compound catabolic process GO:1901658 413 0.025
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.025
regulation of transferase activity GO:0051338 355 0.025
purine ribonucleoside metabolic process GO:0046128 437 0.025
organophosphate catabolic process GO:0046434 430 0.025
negative regulation of multicellular organismal process GO:0051241 317 0.025
ribonucleoside catabolic process GO:0042454 406 0.025
antigen processing and presentation of exogenous peptide antigen via mhc class ii GO:0019886 4 0.024
negative regulation of hydrolase activity GO:0051346 182 0.024
negative regulation of cellular protein metabolic process GO:0032269 353 0.024
oogenesis GO:0048477 2 0.024
positive regulation of secretion GO:0051047 116 0.023
actin filament based process GO:0030029 224 0.023
signal transduction by phosphorylation GO:0023014 297 0.023
negative regulation of cell death GO:0060548 345 0.023
nucleoside triphosphate catabolic process GO:0009143 394 0.023
response to cytokine GO:0034097 232 0.023
regulation of proteolysis GO:0030162 293 0.023
regulation of cell migration GO:0030334 289 0.023
cytokine secretion GO:0050663 64 0.023
cellular macromolecule catabolic process GO:0044265 380 0.022
response to fungus GO:0009620 4 0.022
ribonucleoside triphosphate metabolic process GO:0009199 412 0.022
negative regulation of cellular component organization GO:0051129 235 0.022
leukocyte proliferation GO:0070661 74 0.022
regulation of cell differentiation GO:0045595 393 0.022
regulation of protein processing GO:0070613 150 0.022
hematopoietic or lymphoid organ development GO:0048534 186 0.022
small gtpase mediated signal transduction GO:0007264 78 0.022
positive regulation of cellular component organization GO:0051130 376 0.022
hemopoiesis GO:0030097 180 0.022
humoral immune response GO:0006959 49 0.022
nucleoside phosphate catabolic process GO:1901292 412 0.022
female gamete generation GO:0007292 2 0.022
peptide secretion GO:0002790 51 0.021
peptide antigen assembly with mhc protein complex GO:0002501 4 0.021
purine ribonucleoside catabolic process GO:0046130 398 0.021
cellular protein catabolic process GO:0044257 261 0.021
vesicle mediated transport GO:0016192 371 0.021
purine nucleotide catabolic process GO:0006195 405 0.021
regulation of mapk cascade GO:0043408 262 0.021
protein catabolic process GO:0030163 325 0.021
rho protein signal transduction GO:0007266 26 0.021
regulation of cellular response to stress GO:0080135 244 0.021
regulation of kinase activity GO:0043549 314 0.021
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.021
nucleotide catabolic process GO:0009166 408 0.021
purine nucleoside triphosphate metabolic process GO:0009144 412 0.021
immune system development GO:0002520 195 0.020
purine containing compound catabolic process GO:0072523 411 0.020
mapk cascade GO:0000165 288 0.020
purine nucleoside triphosphate catabolic process GO:0009146 392 0.020
nucleoside triphosphate metabolic process GO:0009141 422 0.020
ribonucleotide catabolic process GO:0009261 405 0.020
positive regulation of developmental process GO:0051094 314 0.020
chemical homeostasis GO:0048878 306 0.020
ras protein signal transduction GO:0007265 73 0.020
regulation of response to wounding GO:1903034 101 0.020
intracellular protein transport GO:0006886 270 0.020
monocarboxylic acid metabolic process GO:0032787 185 0.020
regulation of protein kinase activity GO:0045859 289 0.020
memory GO:0007613 3 0.019
negative regulation of phosphorus metabolic process GO:0010563 267 0.019
cation transport GO:0006812 331 0.019
negative regulation of programmed cell death GO:0043069 321 0.019
regulation of secretion by cell GO:1903530 177 0.019
neuromuscular junction development GO:0007528 3 0.019
purine ribonucleotide catabolic process GO:0009154 404 0.019
neurological system process GO:0050877 163 0.019
positive regulation of kinase activity GO:0033674 204 0.019
ribonucleoside triphosphate catabolic process GO:0009203 391 0.019
detection of biotic stimulus GO:0009595 21 0.019
positive regulation of t cell activation GO:0050870 54 0.018
t cell activation GO:0042110 99 0.018
positive regulation of myeloid leukocyte cytokine production involved in immune response GO:0061081 1 0.018
positive regulation of hydrolase activity GO:0051345 331 0.018
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.018
activation of immune response GO:0002253 114 0.018
negative regulation of apoptotic process GO:0043066 316 0.018
cellular response to ammonium ion GO:0071242 4 0.018
t cell selection GO:0045058 4 0.018
regulation of hormone levels GO:0010817 125 0.018
positive regulation of apoptotic process GO:0043065 246 0.018
nucleoside catabolic process GO:0009164 408 0.018
locomotory behavior GO:0007626 1 0.018
regulation of cytokine secretion GO:0050707 57 0.018
cell adhesion GO:0007155 325 0.017
positive regulation of mononuclear cell proliferation GO:0032946 47 0.017
segmentation GO:0035282 4 0.017
positive regulation of leukocyte proliferation GO:0070665 48 0.017
carbohydrate derivative biosynthetic process GO:1901137 207 0.017
mitotic cell cycle process GO:1903047 286 0.017
posttranscriptional regulation of gene expression GO:0010608 213 0.017
regulation of interferon gamma production GO:0032649 36 0.017
positive regulation of cellular catabolic process GO:0031331 284 0.017
antigen processing and presentation of peptide antigen GO:0048002 18 0.017
positive regulation of protein phosphorylation GO:0001934 313 0.017
regulation of purine nucleotide catabolic process GO:0033121 205 0.017
regulation of peptidase activity GO:0052547 180 0.017
positive regulation of transferase activity GO:0051347 227 0.017
positive regulation of catabolic process GO:0009896 310 0.017
endocytosis GO:0006897 159 0.017
protein processing GO:0016485 226 0.017
cellular chemical homeostasis GO:0055082 180 0.017
negative regulation of phosphate metabolic process GO:0045936 267 0.016
membrane organization GO:0061024 292 0.016
regeneration GO:0031099 4 0.016
cell morphogenesis GO:0000902 296 0.016
regulation of t cell proliferation GO:0042129 42 0.016
negative regulation of response to external stimulus GO:0032102 83 0.016
positive regulation of secretion by cell GO:1903532 108 0.016
cell projection organization GO:0030030 252 0.016
t cell proliferation GO:0042098 45 0.016
positive regulation of programmed cell death GO:0043068 249 0.016
cellular response to dna damage stimulus GO:0006974 379 0.016
protein ubiquitination GO:0016567 314 0.016
cellular response to endogenous stimulus GO:0071495 336 0.016
response to abiotic stimulus GO:0009628 336 0.016
regulation of t cell activation GO:0050863 77 0.016
negative regulation of intracellular signal transduction GO:1902532 183 0.016
protein secretion GO:0009306 98 0.016
actin cytoskeleton organization GO:0030036 207 0.016
organonitrogen compound biosynthetic process GO:1901566 200 0.016
regulation of cellular component biogenesis GO:0044087 281 0.015
single organism cellular localization GO:1902580 332 0.015
cytoplasmic transport GO:0016482 379 0.015
mitotic cell cycle GO:0000278 326 0.015
regulation of cytoskeleton organization GO:0051493 177 0.015
regulation of intracellular transport GO:0032386 195 0.015
guanosine containing compound catabolic process GO:1901069 239 0.015
antigen processing and presentation of exogenous antigen GO:0019884 4 0.015
cellular lipid metabolic process GO:0044255 303 0.015
regulation of apoptotic signaling pathway GO:2001233 175 0.015
protein localization to organelle GO:0033365 280 0.015
regulation of nucleotide metabolic process GO:0006140 269 0.015
gtp catabolic process GO:0006184 237 0.015
regulation of homeostatic process GO:0032844 121 0.015
apoptotic signaling pathway GO:0097190 268 0.015
immune response regulating signaling pathway GO:0002764 97 0.015
reactive oxygen species metabolic process GO:0072593 75 0.014
regulation of protein stability GO:0031647 87 0.014
protein modification by small protein conjugation GO:0032446 342 0.014
inflammatory response GO:0006954 79 0.014
nervous system development GO:0007399 293 0.014
lymphocyte mediated immunity GO:0002449 48 0.014
regulation of i kappab kinase nf kappab signaling GO:0043122 162 0.014
cellular response to lipid GO:0071396 127 0.014
positive regulation of cell migration GO:0030335 172 0.014
positive regulation of cell death GO:0010942 263 0.014
taxis GO:0042330 157 0.014
oocyte differentiation GO:0009994 2 0.014
regulation of protein secretion GO:0050708 86 0.014
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.014
negative regulation of peptidase activity GO:0010466 91 0.014
ion homeostasis GO:0050801 230 0.014
response to lipid GO:0033993 206 0.014
positive regulation of nucleotide catabolic process GO:0030813 185 0.014
regulation of protein maturation GO:1903317 150 0.014
antigen processing and presentation of peptide antigen via mhc class ii GO:0002495 11 0.014
single organism membrane organization GO:0044802 268 0.014
regulation of purine nucleotide metabolic process GO:1900542 264 0.014
oocyte development GO:0048599 1 0.014
regulation of nucleotide catabolic process GO:0030811 205 0.014
positive regulation of nucleotide metabolic process GO:0045981 230 0.014
positive regulation of organelle organization GO:0010638 195 0.014
cellular cation homeostasis GO:0030003 163 0.014
positive regulation of protein transport GO:0051222 135 0.014
cell development GO:0048468 328 0.014
protein targeting GO:0006605 187 0.014
regulation of anatomical structure morphogenesis GO:0022603 286 0.013
biological adhesion GO:0022610 331 0.013
peptidyl tyrosine phosphorylation GO:0018108 170 0.013
interferon gamma production GO:0032609 39 0.013
ubiquitin dependent protein catabolic process GO:0006511 206 0.013
spermatid differentiation GO:0048515 4 0.013
immune response activating signal transduction GO:0002757 90 0.013
regulation of cellular component movement GO:0051270 334 0.013
signal release GO:0023061 70 0.013
negative regulation of cell cycle GO:0045786 193 0.013
carbohydrate metabolic process GO:0005975 207 0.013
monocarboxylic acid biosynthetic process GO:0072330 67 0.013
regulation of nucleoside metabolic process GO:0009118 209 0.013
cellular component morphogenesis GO:0032989 314 0.013
azole transport GO:0045117 4 0.013
regulation of cell motility GO:2000145 299 0.013
modification dependent protein catabolic process GO:0019941 209 0.013
compound eye development GO:0048749 1 0.013
divalent metal ion transport GO:0070838 152 0.013
nuclear transport GO:0051169 179 0.013
negative regulation of cellular amine metabolic process GO:0033239 3 0.013
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.013
antigen processing and presentation of exogenous peptide antigen GO:0002478 4 0.013
regulation of endopeptidase activity GO:0052548 170 0.013
response to organic cyclic compound GO:0014070 204 0.013
oxidation reduction process GO:0055114 396 0.013
small molecule biosynthetic process GO:0044283 157 0.013
negative regulation of phosphorylation GO:0042326 174 0.013
positive regulation of mapk cascade GO:0043410 190 0.013
detection of stimulus GO:0051606 85 0.013
leukocyte mediated immunity GO:0002443 59 0.013
circadian behavior GO:0048512 2 0.013
organelle assembly GO:0070925 176 0.013
blastoderm segmentation GO:0007350 2 0.013
cation homeostasis GO:0055080 189 0.013
regulation of locomotion GO:0040012 329 0.013
cellular ion homeostasis GO:0006873 168 0.013
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.013
guanosine containing compound metabolic process GO:1901068 244 0.013
positive regulation of nucleoside metabolic process GO:0045979 186 0.013
regulation of cell cycle process GO:0010564 266 0.013
t cell differentiation in thymus GO:0033077 4 0.012
negative regulation of protein maturation GO:1903318 142 0.012
response to virus GO:0009615 126 0.012
regulation of vesicle mediated transport GO:0060627 130 0.012
dephosphorylation GO:0016311 209 0.012
hormone secretion GO:0046879 65 0.012
negative regulation of defense response GO:0031348 47 0.012
cellular response to cytokine stimulus GO:0071345 181 0.012
regulation of protein serine threonine kinase activity GO:0071900 179 0.012
regulation of cell adhesion GO:0030155 166 0.012
regulation of cell cycle GO:0051726 393 0.012
negative regulation of response to wounding GO:1903035 47 0.012
regulation of cell development GO:0060284 161 0.012
cytokine mediated signaling pathway GO:0019221 109 0.012
organic acid biosynthetic process GO:0016053 97 0.012
negative regulation of protein processing GO:0010955 142 0.012
positive regulation of innate immune response GO:0045089 79 0.012
spermatid development GO:0007286 4 0.012
positive regulation of defense response GO:0031349 87 0.012
endomembrane system organization GO:0010256 196 0.012
reactive nitrogen species metabolic process GO:2001057 3 0.012
adaptive immune response GO:0002250 49 0.012
nerve development GO:0021675 4 0.012
cellular response to glucocorticoid stimulus GO:0071385 4 0.012
defense response to other organism GO:0098542 129 0.012
regulation of innate immune response GO:0045088 97 0.012
negative regulation of protein modification process GO:0031400 200 0.012
actin filament organization GO:0007015 128 0.012
carboxylic acid biosynthetic process GO:0046394 97 0.012
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.012
intrinsic apoptotic signaling pathway GO:0097193 127 0.012
reactive oxygen species biosynthetic process GO:1903409 4 0.012
positive regulation of t cell proliferation GO:0042102 33 0.012
single organism carbohydrate metabolic process GO:0044723 193 0.012
divalent inorganic cation homeostasis GO:0072507 136 0.012
leukocyte differentiation GO:0002521 98 0.012
regulation of intracellular protein transport GO:0033157 123 0.012
hormone transport GO:0009914 68 0.012
anterior posterior axis specification GO:0009948 2 0.012
negative regulation of transport GO:0051051 176 0.012
regulation of multi organism process GO:0043900 157 0.012
neuroblast proliferation GO:0007405 4 0.012
cation transmembrane transport GO:0098655 238 0.012
interleukin 10 production GO:0032613 17 0.012
i kappab kinase nf kappab signaling GO:0007249 166 0.012
de novo protein folding GO:0006458 2 0.012
nucleoside monophosphate metabolic process GO:0009123 191 0.012
amide transport GO:0042886 76 0.012
interspecies interaction between organisms GO:0044419 156 0.012
lipid biosynthetic process GO:0008610 177 0.011
adult locomotory behavior GO:0008344 1 0.011
polysaccharide assembly with mhc class ii protein complex GO:0002506 2 0.011
regulation of actin filament based process GO:0032970 141 0.011
maintenance of location GO:0051235 112 0.011
inner ear morphogenesis GO:0042472 4 0.011
hindbrain development GO:0030902 3 0.011
antigen processing and presentation of peptide or polysaccharide antigen via mhc class ii GO:0002504 12 0.011
response to growth factor GO:0070848 205 0.011
endosomal transport GO:0016197 129 0.011
cell growth GO:0016049 160 0.011
fatty acid metabolic process GO:0006631 115 0.011
modification dependent macromolecule catabolic process GO:0043632 212 0.011
regulation of protein complex assembly GO:0043254 147 0.011
associative learning GO:0008306 1 0.011
negative regulation of antigen processing and presentation GO:0002578 5 0.011
regulation of protein catabolic process GO:0042176 155 0.011
regulation of sequence specific dna binding transcription factor activity GO:0051090 211 0.011
unsaturated fatty acid metabolic process GO:0033559 37 0.011
cell type specific apoptotic process GO:0097285 125 0.011
rhythmic behavior GO:0007622 2 0.011
generation of neurons GO:0048699 152 0.011
peptidyl tyrosine modification GO:0018212 170 0.011
positive regulation of gtp catabolic process GO:0033126 166 0.011
microtubule based process GO:0007017 210 0.011
ribonucleoside monophosphate metabolic process GO:0009161 187 0.011
neurotransmitter secretion GO:0007269 4 0.011
positive regulation of gtpase activity GO:0043547 166 0.011
response to hormone GO:0009725 175 0.011
positive regulation of i kappab kinase nf kappab signaling GO:0043123 132 0.011
negative regulation of cell differentiation GO:0045596 171 0.011
ameboidal type cell migration GO:0001667 135 0.011
positive regulation of cellular component biogenesis GO:0044089 158 0.011
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.011
cell cycle phase transition GO:0044770 173 0.011
regulation of erk1 and erk2 cascade GO:0070372 99 0.011
positive regulation of insulin secretion involved in cellular response to glucose stimulus GO:0035774 3 0.011
regulation of gtpase activity GO:0043087 180 0.011
peripheral nervous system development GO:0007422 2 0.011
positive regulation of intracellular transport GO:0032388 104 0.011
mitotic cell cycle phase transition GO:0044772 162 0.011
peptide hormone secretion GO:0030072 50 0.011
negative regulation of immune response GO:0050777 40 0.011
erk1 and erk2 cascade GO:0070371 104 0.011
response to wounding GO:0009611 168 0.011
cell fate determination GO:0001709 3 0.011
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains GO:0002460 40 0.011
nucleocytoplasmic transport GO:0006913 176 0.011
atp metabolic process GO:0046034 176 0.011
negative regulation of proteolysis GO:0045861 132 0.011
single organism cell adhesion GO:0098602 179 0.011
proteasomal protein catabolic process GO:0010498 176 0.011
regulation of myeloid leukocyte mediated immunity GO:0002886 4 0.011
purine nucleoside monophosphate metabolic process GO:0009126 186 0.011
gtp metabolic process GO:0046039 239 0.011
tripartite regional subdivision GO:0007351 2 0.011
morphogenesis of embryonic epithelium GO:0016331 4 0.010
positive regulation of cellular component movement GO:0051272 181 0.010
regulation of ras protein signal transduction GO:0046578 155 0.010
regulation of ion transport GO:0043269 189 0.010
regulation of glial cell differentiation GO:0045685 3 0.010
cellular metal ion homeostasis GO:0006875 146 0.010
ion transmembrane transport GO:0034220 338 0.010
inorganic ion transmembrane transport GO:0098660 231 0.010
regulation of cysteine type endopeptidase activity GO:2000116 127 0.010
regulation of synaptic plasticity GO:0048167 3 0.010
cellular response to interferon gamma GO:0071346 24 0.010
syncytium formation by plasma membrane fusion GO:0000768 2 0.010
protein localization to nucleus GO:0034504 136 0.010
response to interferon gamma GO:0034341 39 0.010
regulation of small gtpase mediated signal transduction GO:0051056 156 0.010

HLA-DQA2 disease predictions

Disease DO term ID Size Probability Func Analog Org
immune system disease DOID:2914 155 0.069
musculoskeletal system disease DOID:17 223 0.031
connective tissue disease DOID:65 109 0.026
central nervous system disease DOID:331 186 0.025
neurodegenerative disease DOID:1289 102 0.025
nervous system disease DOID:863 431 0.025
disease of metabolism DOID:0014667 295 0.024
hypersensitivity reaction disease DOID:0060056 25 0.020
bone disease DOID:0080001 88 0.019
sensory system disease DOID:0050155 203 0.016
disease of cellular proliferation DOID:14566 174 0.015
eye and adnexa disease DOID:1492 150 0.015
inherited metabolic disorder DOID:655 242 0.014
cancer DOID:162 167 0.013
organ system cancer DOID:0050686 164 0.013
eye disease DOID:5614 149 0.013
brain disease DOID:936 73 0.012