Homo sapiens

31 known processes

DHCR7

7-dehydrocholesterol reductase

(Aliases: SLOS)

DHCR7 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
steroid biosynthetic process GO:0006694 46 1.000
lipid biosynthetic process GO:0008610 177 1.000
lipid metabolic process GO:0006629 381 1.000
long chain fatty acid metabolic process GO:0001676 30 1.000
small molecule biosynthetic process GO:0044283 157 1.000
sterol metabolic process GO:0016125 28 0.998
arachidonic acid metabolic process GO:0019369 14 0.998
response to disaccharide GO:0034285 1 0.988
steroid metabolic process GO:0008202 94 0.986
alcohol metabolic process GO:0006066 114 0.978
organic hydroxy compound biosynthetic process GO:1901617 71 0.975
organic acid biosynthetic process GO:0016053 97 0.970
monocarboxylic acid biosynthetic process GO:0072330 67 0.970
organic hydroxy compound metabolic process GO:1901615 147 0.914
cellular lipid metabolic process GO:0044255 303 0.907
response to sucrose GO:0009744 1 0.903
sterol biosynthetic process GO:0016126 10 0.880
inner ear morphogenesis GO:0042472 4 0.870
monocarboxylic acid metabolic process GO:0032787 185 0.848
alcohol biosynthetic process GO:0046165 52 0.828
unsaturated fatty acid metabolic process GO:0033559 37 0.821
carboxylic acid biosynthetic process GO:0046394 97 0.821
long chain fatty acid biosynthetic process GO:0042759 4 0.745
organic hydroxy compound transport GO:0015850 63 0.734
positive regulation of triglyceride metabolic process GO:0090208 9 0.717
positive regulation of cholesterol storage GO:0010886 4 0.710
fatty acid biosynthetic process GO:0006633 46 0.707
mating GO:0007618 1 0.699
response to lipid GO:0033993 206 0.698
cholesterol metabolic process GO:0008203 28 0.695
determination of adult lifespan GO:0008340 2 0.680
positive regulation of triglyceride biosynthetic process GO:0010867 4 0.669
serotonin transport GO:0006837 3 0.557
fatty acid metabolic process GO:0006631 115 0.549
multicellular organismal aging GO:0010259 3 0.529
unsaturated fatty acid biosynthetic process GO:0006636 21 0.525
neurotransmitter secretion GO:0007269 4 0.524
monoamine transport GO:0015844 10 0.467
cellular response to nutrient levels GO:0031669 69 0.425
serotonin secretion GO:0001820 1 0.380
cation transport GO:0006812 331 0.353
sterol esterification GO:0034434 10 0.344
defense response GO:0006952 315 0.329
negative regulation of growth of symbiont in host GO:0044130 1 0.297
cholesterol transport GO:0030301 39 0.264
positive regulation of lipid storage GO:0010884 10 0.259
cholesterol biosynthetic process GO:0006695 10 0.208
actin cytoskeleton organization GO:0030036 207 0.202
regulation of innate immune response GO:0045088 97 0.187
icosanoid metabolic process GO:0006690 35 0.175
post embryonic development GO:0009791 2 0.167
Mouse
cellular macromolecular complex assembly GO:0034622 324 0.165
male genitalia development GO:0030539 1 0.157
cellular component assembly involved in morphogenesis GO:0010927 73 0.148
triglyceride metabolic process GO:0006641 23 0.147
vesicle mediated transport GO:0016192 371 0.141
cellular response to external stimulus GO:0071496 111 0.136
negative regulation of growth of symbiont involved in interaction with host GO:0044146 2 0.133
innate immune response GO:0045087 178 0.130
maintenance of location GO:0051235 112 0.126
cell cell signaling GO:0007267 155 0.124
cellular protein complex assembly GO:0043623 188 0.120
negative regulation of protein metabolic process GO:0051248 391 0.111
growth GO:0040007 202 0.110
Mouse
muscle system process GO:0003012 81 0.104
response to organonitrogen compound GO:0010243 156 0.103
hormone metabolic process GO:0042445 61 0.101
endosomal transport GO:0016197 129 0.098
striated muscle myosin thick filament assembly GO:0071688 2 0.096
regulation of defense response GO:0031347 154 0.096
response to nutrient GO:0007584 20 0.096
nitrogen compound transport GO:0071705 191 0.095
system process GO:0003008 349 0.094
fat cell differentiation GO:0045444 32 0.090
myosin filament assembly GO:0031034 2 0.088
glycerolipid metabolic process GO:0046486 107 0.087
cellular alcohol metabolic process GO:0044107 7 0.086
Yeast
regulation of growth of symbiont in host GO:0044126 1 0.086
acylglycerol metabolic process GO:0006639 27 0.082
response to hormone GO:0009725 175 0.082
response to organic cyclic compound GO:0014070 204 0.075
signal release GO:0023061 70 0.074
protein processing GO:0016485 226 0.072
cellular component morphogenesis GO:0032989 314 0.072
fatty acid derivative metabolic process GO:1901568 35 0.067
response to nutrient levels GO:0031667 81 0.067
lipid localization GO:0010876 106 0.066
growth of symbiont involved in interaction with host GO:0044116 2 0.066
cellular response to starvation GO:0009267 58 0.065
growth involved in symbiotic interaction GO:0044110 2 0.065
negative regulation of proteolysis GO:0045861 132 0.064
oxidation reduction process GO:0055114 396 0.063
cholesterol homeostasis GO:0042632 28 0.060
visual behavior GO:0007632 2 0.059
growth of symbiont in host GO:0044117 1 0.055
cellular response to sterol GO:0036315 7 0.054
associative learning GO:0008306 1 0.054
cellular response to extracellular stimulus GO:0031668 72 0.052
sterol transport GO:0015918 39 0.052
immune response GO:0006955 307 0.051
protein maturation GO:0051604 233 0.050
reproductive process GO:0022414 106 0.049
isoprenoid metabolic process GO:0006720 39 0.048
response to starvation GO:0042594 59 0.048
myosin filament organization GO:0031033 2 0.048
response to oxygen containing compound GO:1901700 369 0.044
excretion GO:0007588 9 0.044
endocytic recycling GO:0032456 12 0.044
cholesterol esterification GO:0034435 10 0.042
cellular alcohol biosynthetic process GO:0044108 7 0.042
Yeast
sensory organ morphogenesis GO:0090596 21 0.041
phosphatidylcholine catabolic process GO:0034638 3 0.041
acetylcholine secretion GO:0061526 1 0.040
gland development GO:0048732 48 0.038
secretion by cell GO:0032940 226 0.038
purine containing compound catabolic process GO:0072523 411 0.038
negative regulation of protein processing GO:0010955 142 0.037
lipid catabolic process GO:0016042 84 0.037
acetylcholine transport GO:0015870 1 0.036
response to nitrogen compound GO:1901698 184 0.036
response to extracellular stimulus GO:0009991 85 0.035
central nervous system development GO:0007417 123 0.035
muscle contraction GO:0006936 73 0.034
anatomical structure formation involved in morphogenesis GO:0048646 284 0.034
positive regulation of developmental growth GO:0048639 16 0.034
actomyosin structure organization GO:0031032 59 0.034
actin filament based process GO:0030029 224 0.033
immune system development GO:0002520 195 0.033
response to carbohydrate GO:0009743 21 0.033
organelle assembly GO:0070925 176 0.033
amyloid precursor protein metabolic process GO:0042982 17 0.033
defense response to bacterium GO:0042742 63 0.033
liver development GO:0001889 9 0.033
secretion GO:0046903 254 0.033
ketone body metabolic process GO:1902224 2 0.031
atp metabolic process GO:0046034 176 0.031
amine metabolic process GO:0009308 44 0.031
lipid homeostasis GO:0055088 39 0.030
skin development GO:0043588 76 0.030
lipid transport GO:0006869 90 0.030
sterol homeostasis GO:0055092 28 0.030
fatty acid elongation polyunsaturated fatty acid GO:0034626 4 0.029
regulation of cellular ketone metabolic process GO:0010565 50 0.029
amyloid precursor protein catabolic process GO:0042987 12 0.029
cholesterol efflux GO:0033344 28 0.029
organic anion transport GO:0015711 103 0.029
response to peptide GO:1901652 65 0.028
negative regulation of endopeptidase activity GO:0010951 84 0.028
regulation of protein processing GO:0070613 150 0.028
negative regulation of cellular protein metabolic process GO:0032269 353 0.028
very long chain fatty acid biosynthetic process GO:0042761 7 0.028
response to other organism GO:0051707 261 0.028
response to fungus GO:0009620 4 0.028
cellular response to hormone stimulus GO:0032870 125 0.028
lipid storage GO:0019915 28 0.027
negative regulation of cholesterol transport GO:0032375 8 0.027
protein homooligomerization GO:0051260 100 0.027
carboxylic acid transport GO:0046942 63 0.027
protein oligomerization GO:0051259 173 0.026
anion transport GO:0006820 161 0.026
regulation of vesicle mediated transport GO:0060627 130 0.026
negative regulation of growth GO:0045926 97 0.026
response to biotic stimulus GO:0009607 276 0.026
negative regulation of cellular amino acid metabolic process GO:0045763 2 0.025
muscle cell development GO:0055001 29 0.025
ribonucleoside triphosphate catabolic process GO:0009203 391 0.025
organophosphate catabolic process GO:0046434 430 0.024
ear morphogenesis GO:0042471 7 0.024
membrane organization GO:0061024 292 0.024
interspecies interaction between organisms GO:0044419 156 0.024
ribonucleoside monophosphate catabolic process GO:0009158 158 0.024
regulation of hormone levels GO:0010817 125 0.024
chemical homeostasis GO:0048878 306 0.023
neurotransmitter transport GO:0006836 10 0.023
negative regulation of catalytic activity GO:0043086 335 0.023
negative regulation of hydrolase activity GO:0051346 182 0.023
negative regulation of peptidase activity GO:0010466 91 0.023
aging GO:0007568 66 0.023
neutral lipid metabolic process GO:0006638 27 0.023
response to abiotic stimulus GO:0009628 336 0.023
negative regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043154 46 0.023
response to oxygen levels GO:0070482 100 0.023
regulation of peptidase activity GO:0052547 180 0.023
ribonucleoside monophosphate metabolic process GO:0009161 187 0.023
regulation of cellular amino acid metabolic process GO:0006521 6 0.022
striated muscle cell development GO:0055002 27 0.022
cellular response to follicle stimulating hormone stimulus GO:0071372 1 0.022
mitotic cytokinesis GO:0000281 19 0.022
purine nucleotide catabolic process GO:0006195 405 0.022
regulation of neurotransmitter levels GO:0001505 15 0.022
regulation of proteolysis GO:0030162 293 0.022
mitotic cell cycle process GO:1903047 286 0.022
cellular amino acid metabolic process GO:0006520 116 0.021
positive regulation of nucleoside metabolic process GO:0045979 186 0.021
striated muscle cell differentiation GO:0051146 43 0.021
regulation of cholesterol homeostasis GO:2000188 2 0.021
regulation of steroid biosynthetic process GO:0050810 23 0.020
regulation of protein maturation GO:1903317 150 0.020
regulation of protein kinase activity GO:0045859 289 0.020
ribonucleoside triphosphate metabolic process GO:0009199 412 0.020
head development GO:0060322 108 0.020
nervous system development GO:0007399 293 0.020
reproduction GO:0000003 63 0.020
regulation of nucleoside metabolic process GO:0009118 209 0.020
regulation of cellular amine metabolic process GO:0033238 11 0.020
defense response to gram positive bacterium GO:0050830 29 0.019
cell development GO:0048468 328 0.019
nucleoside monophosphate catabolic process GO:0009125 159 0.019
negative regulation of cysteine type endopeptidase activity GO:2000117 48 0.019
positive regulation of synaptic transmission GO:0050806 4 0.018
negative regulation of cellular amine metabolic process GO:0033239 3 0.018
cytoskeleton dependent cytokinesis GO:0061640 22 0.018
response to phenylpropanoid GO:0080184 1 0.018
atp catabolic process GO:0006200 157 0.018
lipoprotein metabolic process GO:0042157 42 0.018
neuromuscular junction development GO:0007528 3 0.018
response to vitamin GO:0033273 13 0.018
response to oxidative stress GO:0006979 121 0.018
negative regulation of transport GO:0051051 176 0.018
cellular amine metabolic process GO:0044106 41 0.017
mitotic cell cycle GO:0000278 326 0.017
neutral lipid biosynthetic process GO:0046460 11 0.017
multi multicellular organism process GO:0044706 18 0.017
response to peptide hormone GO:0043434 61 0.017
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.017
nucleoside triphosphate metabolic process GO:0009141 422 0.017
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.017
regulation of purine nucleotide metabolic process GO:1900542 264 0.017
purine nucleoside monophosphate catabolic process GO:0009128 158 0.016
purine nucleoside triphosphate metabolic process GO:0009144 412 0.016
regulation of synaptic transmission dopaminergic GO:0032225 4 0.016
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.016
regulation of lipid metabolic process GO:0019216 96 0.016
response to external biotic stimulus GO:0043207 261 0.016
negative regulation of protein maturation GO:1903318 142 0.016
multicellular organism growth GO:0035264 8 0.016
Mouse
zymogen activation GO:0031638 70 0.016
dephosphorylation GO:0016311 209 0.016
multicellular organismal reproductive process GO:0048609 40 0.016
endocytosis GO:0006897 159 0.016
reproductive system development GO:0061458 56 0.016
response to decreased oxygen levels GO:0036293 96 0.016
intestinal absorption GO:0050892 4 0.016
multi organism reproductive process GO:0044703 54 0.015
oogenesis GO:0048477 2 0.015
small molecule catabolic process GO:0044282 92 0.015
response to light stimulus GO:0009416 87 0.015
regulation of cysteine type endopeptidase activity GO:2000116 127 0.015
sphingolipid metabolic process GO:0006665 38 0.015
regulation of nucleotide catabolic process GO:0030811 205 0.015
nucleoside monophosphate metabolic process GO:0009123 191 0.015
nucleotide catabolic process GO:0009166 408 0.015
regulation of fatty acid biosynthetic process GO:0042304 9 0.015
mitochondrial transport GO:0006839 60 0.014
isoprenoid biosynthetic process GO:0008299 9 0.014
monosaccharide metabolic process GO:0005996 74 0.014
acylglycerol biosynthetic process GO:0046463 11 0.014
positive regulation of cellular component organization GO:0051130 376 0.014
negative regulation of phosphate metabolic process GO:0045936 267 0.014
purine ribonucleoside catabolic process GO:0046130 398 0.014
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.014
positive regulation of developmental process GO:0051094 314 0.014
regulation of inflammatory response GO:0050727 46 0.014
response to low density lipoprotein particle GO:0055098 4 0.014
muscle cell differentiation GO:0042692 63 0.014
purine ribonucleotide catabolic process GO:0009154 404 0.014
ion homeostasis GO:0050801 230 0.014
negative regulation of lipid metabolic process GO:0045833 38 0.014
regulation of atpase activity GO:0043462 25 0.014
defense response to other organism GO:0098542 129 0.013
triglyceride biosynthetic process GO:0019432 10 0.013
cellular response to lipid GO:0071396 127 0.013
carbohydrate metabolic process GO:0005975 207 0.013
positive regulation of nucleotide catabolic process GO:0030813 185 0.013
multi organism behavior GO:0051705 14 0.013
purine ribonucleoside metabolic process GO:0046128 437 0.013
regulation of synaptic vesicle endocytosis GO:1900242 1 0.013
segmentation GO:0035282 4 0.013
positive regulation of nucleotide metabolic process GO:0045981 230 0.013
regeneration GO:0031099 4 0.013
regulation of secretion by cell GO:1903530 177 0.013
phospholipid metabolic process GO:0006644 99 0.012
phospholipid biosynthetic process GO:0008654 44 0.012
synaptic vesicle recycling GO:0036465 3 0.012
memory GO:0007613 3 0.012
regulation of endopeptidase activity GO:0052548 170 0.012
osteoblast differentiation GO:0001649 92 0.012
regulation of purine nucleotide catabolic process GO:0033121 205 0.012
regulation of growth GO:0040008 165 0.012
coenzyme metabolic process GO:0006732 65 0.012
srebp signaling pathway GO:0032933 4 0.012
cellular homeostasis GO:0019725 196 0.012
organic acid transport GO:0015849 65 0.012
negative regulation of apoptotic process GO:0043066 316 0.012
behavioral response to ethanol GO:0048149 2 0.012
cellular response to cytokine stimulus GO:0071345 181 0.012
multicellular organism reproduction GO:0032504 42 0.012
organophosphate biosynthetic process GO:0090407 163 0.012
negative regulation of cellular component organization GO:0051129 235 0.012
symbiosis encompassing mutualism through parasitism GO:0044403 156 0.012
transmembrane transport GO:0055085 399 0.012
blastoderm segmentation GO:0007350 2 0.012
positive regulation of cell proliferation GO:0008284 301 0.012
regulation of dopamine uptake involved in synaptic transmission GO:0051584 4 0.012
protein catabolic process GO:0030163 325 0.012
cellular response to oxygen containing compound GO:1901701 276 0.011
locomotory behavior GO:0007626 1 0.011
negative regulation of multi organism process GO:0043901 92 0.011
nucleoside triphosphate catabolic process GO:0009143 394 0.011
regulation of endocytosis GO:0030100 72 0.011
single organism membrane organization GO:0044802 268 0.011
ribonucleotide catabolic process GO:0009261 405 0.011
purine nucleoside monophosphate metabolic process GO:0009126 186 0.011
demethylation GO:0070988 37 0.011
regulation of synaptic vesicle transport GO:1902803 3 0.011
short chain fatty acid metabolic process GO:0046459 2 0.011
regulation of lipid transport by regulation of transcription from rna polymerase ii promoter GO:0072367 4 0.011
ossification GO:0001503 121 0.011
brain development GO:0007420 97 0.011
response to glucagon GO:0033762 1 0.011
regulation of fatty acid metabolic process GO:0019217 24 0.010
behavior GO:0007610 112 0.010
regulation of cytoplasmic transport GO:1903649 149 0.010
regulation of transferase activity GO:0051338 355 0.010
negative regulation of protein modification process GO:0031400 200 0.010
regulation of cytokine production GO:0001817 232 0.010
nucleoside phosphate catabolic process GO:1901292 412 0.010
negative regulation of response to external stimulus GO:0032102 83 0.010

DHCR7 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.062
inherited metabolic disorder DOID:655 242 0.046
amino acid metabolic disorder DOID:9252 50 0.026
central nervous system disease DOID:331 186 0.023
nervous system disease DOID:863 431 0.023
immune system disease DOID:2914 155 0.015
anemia DOID:2355 55 0.010
hematopoietic system disease DOID:74 100 0.010
neurodegenerative disease DOID:1289 102 0.010
lipid metabolism disorder DOID:3146 26 0.005