Homo sapiens

7 known processes

AFG3L2

AFG3 ATPase family gene 3-like 2 (S. cerevisiae)

(Aliases: FLJ25993,SCA28)

AFG3L2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
post embryonic development GO:0009791 2 0.417
Worm
vesicle mediated transport GO:0016192 371 0.380
Worm
multicellular organismal aging GO:0010259 3 0.255
Worm
tricarboxylic acid metabolic process GO:0072350 4 0.225
mitochondrion organization GO:0007005 156 0.155
Mouse
tricarboxylic acid cycle GO:0006099 4 0.145
determination of adult lifespan GO:0008340 2 0.143
Worm
nucleoside triphosphate metabolic process GO:0009141 422 0.124
Yeast
nucleoside monophosphate metabolic process GO:0009123 191 0.109
Yeast
citrate metabolic process GO:0006101 2 0.106
ribonucleoside triphosphate metabolic process GO:0009199 412 0.100
Yeast
endocytosis GO:0006897 159 0.094
Worm
purine ribonucleoside metabolic process GO:0046128 437 0.093
Yeast
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.076
Yeast
cellular amino acid metabolic process GO:0006520 116 0.075
purine nucleoside triphosphate metabolic process GO:0009144 412 0.074
Yeast
ribonucleoside monophosphate metabolic process GO:0009161 187 0.074
Yeast
oxidation reduction process GO:0055114 396 0.072
growth GO:0040007 202 0.067
Mouse
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.065
Yeast
ras protein signal transduction GO:0007265 73 0.063
oogenesis GO:0048477 2 0.059
anion transport GO:0006820 161 0.055
nucleoside catabolic process GO:0009164 408 0.052
Yeast
purine ribonucleoside catabolic process GO:0046130 398 0.051
Yeast
purine nucleotide catabolic process GO:0006195 405 0.048
Yeast
purine nucleoside triphosphate catabolic process GO:0009146 392 0.048
Yeast
ribonucleoside catabolic process GO:0042454 406 0.048
Yeast
ion transmembrane transport GO:0034220 338 0.047
dicarboxylic acid biosynthetic process GO:0043650 4 0.047
organic anion transport GO:0015711 103 0.045
embryo development GO:0009790 123 0.044
Worm
atp metabolic process GO:0046034 176 0.044
Yeast
female gamete generation GO:0007292 2 0.043
morphogenesis of embryonic epithelium GO:0016331 4 0.041
generation of precursor metabolites and energy GO:0006091 68 0.041
spermatid development GO:0007286 4 0.041
nucleotide biosynthetic process GO:0009165 109 0.040
energy derivation by oxidation of organic compounds GO:0015980 43 0.039
membrane organization GO:0061024 292 0.039
Mouse
cell development GO:0048468 328 0.039
Mouse
system process GO:0003008 349 0.038
Mouse
purine nucleoside monophosphate metabolic process GO:0009126 186 0.038
Yeast
spermatid differentiation GO:0048515 4 0.038
purine ribonucleotide catabolic process GO:0009154 404 0.038
Yeast
glycosyl compound catabolic process GO:1901658 413 0.038
Yeast
cellular macromolecule catabolic process GO:0044265 380 0.038
reproductive process GO:0022414 106 0.037
regulation of growth GO:0040008 165 0.037
Mouse
cellular respiration GO:0045333 21 0.036
organonitrogen compound biosynthetic process GO:1901566 200 0.036
positive regulation of developmental process GO:0051094 314 0.036
nucleotide catabolic process GO:0009166 408 0.034
Yeast
tissue regeneration GO:0042246 3 0.034
inorganic ion transmembrane transport GO:0098660 231 0.034
posttranscriptional regulation of gene expression GO:0010608 213 0.034
organophosphate biosynthetic process GO:0090407 163 0.033
ribonucleoside triphosphate catabolic process GO:0009203 391 0.033
Yeast
ribonucleotide catabolic process GO:0009261 405 0.032
Yeast
regulation of peptidase activity GO:0052547 180 0.032
cellular protein complex assembly GO:0043623 188 0.032
Worm
regeneration GO:0031099 4 0.032
lipid metabolic process GO:0006629 381 0.031
purine ribonucleotide biosynthetic process GO:0009152 79 0.030
cellular component morphogenesis GO:0032989 314 0.030
Mouse
single organism cellular localization GO:1902580 332 0.030
protein maturation GO:0051604 233 0.029
Yeast Mouse
protein processing GO:0016485 226 0.029
Yeast Mouse
organophosphate catabolic process GO:0046434 430 0.028
Yeast
regulation of endopeptidase activity GO:0052548 170 0.028
memory GO:0007613 3 0.028
positive regulation of catabolic process GO:0009896 310 0.028
purine nucleoside catabolic process GO:0006152 398 0.028
Yeast
protein localization to organelle GO:0033365 280 0.027
blastoderm segmentation GO:0007350 2 0.027
actin filament based process GO:0030029 224 0.027
nucleoside triphosphate catabolic process GO:0009143 394 0.027
Yeast
ribonucleotide biosynthetic process GO:0009260 81 0.027
cation transmembrane transport GO:0098655 238 0.027
intracellular protein transport GO:0006886 270 0.026
cation transport GO:0006812 331 0.026
lipid localization GO:0010876 106 0.026
wound healing GO:0042060 115 0.026
response to abiotic stimulus GO:0009628 336 0.025
aging GO:0007568 66 0.025
Yeast Worm
positive regulation of hydrolase activity GO:0051345 331 0.025
monocarboxylic acid metabolic process GO:0032787 185 0.025
biological adhesion GO:0022610 331 0.025
negative regulation of multicellular organismal process GO:0051241 317 0.025
mating GO:0007618 1 0.025
glycerol metabolic process GO:0006071 4 0.025
single organism membrane organization GO:0044802 268 0.025
Mouse
positive regulation of programmed cell death GO:0043068 249 0.025
zymogen activation GO:0031638 70 0.024
carbohydrate derivative biosynthetic process GO:1901137 207 0.024
cell adhesion GO:0007155 325 0.024
nucleoside monophosphate catabolic process GO:0009125 159 0.023
Yeast
neurological system process GO:0050877 163 0.023
Mouse
dicarboxylic acid metabolic process GO:0043648 29 0.023
anterior posterior axis specification GO:0009948 2 0.023
small gtpase mediated signal transduction GO:0007264 78 0.023
reproduction GO:0000003 63 0.023
Worm
cell division GO:0051301 168 0.023
dephosphorylation GO:0016311 209 0.022
positive regulation of cellular catabolic process GO:0031331 284 0.022
oocyte development GO:0048599 1 0.022
cellular ketone metabolic process GO:0042180 80 0.022
cellular macromolecular complex assembly GO:0034622 324 0.021
Worm
single organism reproductive process GO:0044702 98 0.021
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.021
Yeast
neuromuscular junction development GO:0007528 3 0.021
Mouse
organic acid transport GO:0015849 65 0.021
cofactor metabolic process GO:0051186 87 0.020
mitochondrial rna metabolic process GO:0000959 15 0.020
cellular component disassembly GO:0022411 92 0.020
lipid transport GO:0006869 90 0.020
regulation of proteolysis GO:0030162 293 0.020
sulfur compound metabolic process GO:0006790 101 0.020
mitochondrial respiratory chain complex i biogenesis GO:0097031 16 0.020
maintenance of location GO:0051235 112 0.020
activation of cysteine type endopeptidase activity involved in apoptotic process GO:0006919 49 0.020
nervous system development GO:0007399 293 0.020
Mouse
cytokine production GO:0001816 247 0.020
positive regulation of cell death GO:0010942 263 0.020
response to wounding GO:0009611 168 0.019
regulation of purine nucleotide catabolic process GO:0033121 205 0.019
ribose phosphate biosynthetic process GO:0046390 82 0.019
regulation of kinase activity GO:0043549 314 0.019
cytoplasmic transport GO:0016482 379 0.019
actin cytoskeleton organization GO:0030036 207 0.019
negative regulation of phosphate metabolic process GO:0045936 267 0.019
amine metabolic process GO:0009308 44 0.018
cellular amino acid catabolic process GO:0009063 31 0.018
small molecule biosynthetic process GO:0044283 157 0.018
positive regulation of peptidase activity GO:0010952 88 0.018
regulation of cysteine type endopeptidase activity GO:2000116 127 0.018
segmentation GO:0035282 4 0.018
negative regulation of cell death GO:0060548 345 0.018
establishment of protein localization to organelle GO:0072594 172 0.018
regulation of cellular amino acid metabolic process GO:0006521 6 0.017
purine containing compound catabolic process GO:0072523 411 0.017
Yeast
nucleoside phosphate biosynthetic process GO:1901293 109 0.017
response to oxidative stress GO:0006979 121 0.017
reproductive system development GO:0061458 56 0.017
nadh dehydrogenase complex assembly GO:0010257 16 0.017
transmembrane transport GO:0055085 399 0.017
cellular homeostasis GO:0019725 196 0.017
reactive oxygen species metabolic process GO:0072593 75 0.017
microtubule based process GO:0007017 210 0.017
cellular amine metabolic process GO:0044106 41 0.017
microtubule cytoskeleton organization GO:0000226 176 0.017
regulation of immune response GO:0050776 201 0.017
regulation of actin filament based process GO:0032970 141 0.017
negative regulation of programmed cell death GO:0043069 321 0.017
inorganic cation transmembrane transport GO:0098662 194 0.017
regulation of response to external stimulus GO:0032101 222 0.017
purine containing compound biosynthetic process GO:0072522 88 0.017
nucleocytoplasmic transport GO:0006913 176 0.017
chemical homeostasis GO:0048878 306 0.017
atp catabolic process GO:0006200 157 0.017
Yeast
reproductive structure development GO:0048608 55 0.017
regulation of protein kinase activity GO:0045859 289 0.016
adult locomotory behavior GO:0008344 1 0.016
negative regulation of protein metabolic process GO:0051248 391 0.016
negative regulation of cellular protein metabolic process GO:0032269 353 0.016
nucleoside phosphate catabolic process GO:1901292 412 0.016
Yeast
response to biotic stimulus GO:0009607 276 0.016
protein targeting GO:0006605 187 0.016
dna replication GO:0006260 116 0.016
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 116 0.016
negative regulation of cellular component organization GO:0051129 235 0.016
regulation of cellular amine metabolic process GO:0033238 11 0.016
anatomical structure formation involved in morphogenesis GO:0048646 284 0.016
cell growth GO:0016049 160 0.016
mitochondrial atp synthesis coupled electron transport GO:0042775 4 0.016
response to oxygen containing compound GO:1901700 369 0.016
oocyte differentiation GO:0009994 2 0.016
regulation of locomotion GO:0040012 329 0.015
sex differentiation GO:0007548 45 0.015
cellular protein catabolic process GO:0044257 261 0.015
locomotory behavior GO:0007626 1 0.015
regulation of transferase activity GO:0051338 355 0.015
positive regulation of cellular amino acid metabolic process GO:0045764 3 0.015
cell morphogenesis GO:0000902 296 0.015
Mouse
immune response GO:0006955 307 0.015
cellular cation homeostasis GO:0030003 163 0.015
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.015
Yeast
cell cell signaling GO:0007267 155 0.015
Fly
positive regulation of growth GO:0045927 58 0.015
guanosine containing compound catabolic process GO:1901069 239 0.015
epithelium development GO:0060429 227 0.015
negative regulation of intracellular signal transduction GO:1902532 183 0.015
activation of cysteine type endopeptidase activity GO:0097202 57 0.015
purine nucleotide biosynthetic process GO:0006164 84 0.014
purine nucleoside monophosphate catabolic process GO:0009128 158 0.014
Yeast
positive regulation of cysteine type endopeptidase activity GO:2001056 79 0.014
purine ribonucleoside biosynthetic process GO:0046129 23 0.014
fear response GO:0042596 0 0.014
metal ion transport GO:0030001 272 0.014
developmental process involved in reproduction GO:0003006 66 0.014
cellular response to oxygen containing compound GO:1901701 276 0.014
response to nitrogen compound GO:1901698 184 0.014
dicarboxylic acid catabolic process GO:0043649 9 0.014
monovalent inorganic cation transport GO:0015672 128 0.014
cellular chemical homeostasis GO:0055082 180 0.014
anterior posterior axis specification embryo GO:0008595 2 0.014
positive regulation of immune system process GO:0002684 283 0.014
muscle system process GO:0003012 81 0.014
positive regulation of nucleoside metabolic process GO:0045979 186 0.014
ribonucleoside biosynthetic process GO:0042455 25 0.014
mitochondrial transport GO:0006839 60 0.014
cation homeostasis GO:0055080 189 0.013
positive regulation of apoptotic process GO:0043065 246 0.013
cell part morphogenesis GO:0032990 137 0.013
Mouse
positive regulation of proteolysis GO:0045862 142 0.013
intracellular mrna localization GO:0008298 1 0.013
covalent chromatin modification GO:0016569 254 0.013
negative regulation of protein modification process GO:0031400 200 0.013
tripartite regional subdivision GO:0007351 2 0.013
neuron differentiation GO:0030182 138 0.013
Mouse
guanosine containing compound metabolic process GO:1901068 244 0.013
nucleoside biosynthetic process GO:0009163 26 0.013
innate immune response GO:0045087 178 0.013
metal ion homeostasis GO:0055065 169 0.013
behavior GO:0007610 112 0.013
negative regulation of apoptotic process GO:0043066 316 0.013
regulation of protein complex assembly GO:0043254 147 0.013
ion homeostasis GO:0050801 230 0.013
receptor mediated endocytosis GO:0006898 84 0.013
Worm
regulation of nucleotide catabolic process GO:0030811 205 0.013
regulation of cell adhesion GO:0030155 166 0.012
embryo development ending in birth or egg hatching GO:0009792 34 0.012
Worm
rho protein signal transduction GO:0007266 26 0.012
embryonic morphogenesis GO:0048598 85 0.012
negative regulation of catalytic activity GO:0043086 335 0.012
divalent inorganic cation homeostasis GO:0072507 136 0.012
regulation of purine nucleotide metabolic process GO:1900542 264 0.012
regulation of cellular component biogenesis GO:0044087 281 0.012
protein catabolic process GO:0030163 325 0.012
cell cell recognition GO:0009988 4 0.012
sulfur compound biosynthetic process GO:0044272 38 0.012
transcription from mitochondrial promoter GO:0006390 7 0.012
peripheral nervous system development GO:0007422 2 0.012
rna catabolic process GO:0006401 71 0.012
generation of neurons GO:0048699 152 0.012
Mouse
mitotic cell cycle process GO:1903047 286 0.012
negative regulation of cell proliferation GO:0008285 228 0.012
regulation of protein stability GO:0031647 87 0.012
negative regulation of organelle organization GO:0010639 126 0.012
cofactor biosynthetic process GO:0051188 31 0.012
single organism cell adhesion GO:0098602 179 0.012
regulation of cytoplasmic transport GO:1903649 149 0.012
coenzyme metabolic process GO:0006732 65 0.011
rna interference GO:0016246 4 0.011
positive regulation of endopeptidase activity GO:0010950 84 0.011
positive regulation of purine nucleotide metabolic process GO:1900544 227 0.011
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.011
secretion by cell GO:0032940 226 0.011
regulation of membrane potential GO:0042391 95 0.011
Mouse
regulation of cytokine production GO:0001817 232 0.011
regulation of cell cycle process GO:0010564 266 0.011
dna recombination GO:0006310 77 0.011
regulation of cellular ketone metabolic process GO:0010565 50 0.011
protein stabilization GO:0050821 64 0.011
multicellular organismal response to stress GO:0033555 1 0.011
regulation of ras protein signal transduction GO:0046578 155 0.011
alpha amino acid metabolic process GO:1901605 72 0.011
mitotic cell cycle GO:0000278 326 0.011
carbohydrate metabolic process GO:0005975 207 0.011
regulation of cellular response to stress GO:0080135 244 0.011
positive regulation of purine nucleotide catabolic process GO:0033123 185 0.011
response to cytokine GO:0034097 232 0.011
phototransduction GO:0007602 3 0.011
response to hormone GO:0009725 175 0.011
developmental programmed cell death GO:0010623 3 0.011
response to organic cyclic compound GO:0014070 204 0.011
modification dependent protein catabolic process GO:0019941 209 0.011
divalent inorganic cation transport GO:0072511 158 0.011
regulation of small gtpase mediated signal transduction GO:0051056 156 0.011
regulation of intracellular transport GO:0032386 195 0.011
regulation of cell differentiation GO:0045595 393 0.011
defense response GO:0006952 315 0.011
rna splicing GO:0008380 131 0.011
negative regulation of stem cell proliferation GO:2000647 3 0.011
dna conformation change GO:0071103 113 0.011
regulation of nucleotide metabolic process GO:0006140 269 0.011
positive regulation of cellular component organization GO:0051130 376 0.011
nitrogen compound transport GO:0071705 191 0.011
negative regulation of hydrolase activity GO:0051346 182 0.010
regulation of cell motility GO:2000145 299 0.010
cardiovascular system development GO:0072358 262 0.010
negative regulation of phosphorus metabolic process GO:0010563 267 0.010
phosphate ion transmembrane transport GO:0035435 4 0.010
regulation of cell development GO:0060284 161 0.010
histone modification GO:0016570 251 0.010
regulation of cell growth GO:0001558 135 0.010
regulation of cellular component movement GO:0051270 334 0.010
glutamate metabolic process GO:0006536 10 0.010
apoptotic signaling pathway GO:0097190 268 0.010
astrocyte differentiation GO:0048708 4 0.010
cellular response to endogenous stimulus GO:0071495 336 0.010
single organismal cell cell adhesion GO:0016337 148 0.010

AFG3L2 disease predictions

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 295 0.202
inherited metabolic disorder DOID:655 242 0.202
amino acid metabolic disorder DOID:9252 50 0.047
muscular disease DOID:0080000 114 0.029
musculoskeletal system disease DOID:17 223 0.029
central nervous system disease DOID:331 186 0.026
nervous system disease DOID:863 431 0.026
sensory system disease DOID:0050155 203 0.021
eye and adnexa disease DOID:1492 150 0.021
eye disease DOID:5614 149 0.021
muscle tissue disease DOID:66 113 0.019
retinal disease DOID:5679 118 0.018
retinal degeneration DOID:8466 89 0.017
myopathy DOID:423 104 0.014
cancer DOID:162 167 0.014
disease of cellular proliferation DOID:14566 174 0.014
organ system cancer DOID:0050686 164 0.014
immune system disease DOID:2914 155 0.013
hematopoietic system disease DOID:74 100 0.013
mitochondrial metabolism disease DOID:700 29 0.012
neuropathy DOID:870 52 0.011
carbohydrate metabolic disorder DOID:2978 55 0.011
neurodegenerative disease DOID:1289 102 0.008
spinocerebellar degeneration DOID:2478 27 0.005
spinocerebellar ataxia DOID:1441 26 0.004