|
|
rab protein signal transduction
|
GO:0032482 |
4 |
0.929
|
|
|
|
positive regulation of rab gtpase activity
|
GO:0032851 |
39 |
0.792
|
|
|
|
regulation of rab protein signal transduction
|
GO:0032483 |
39 |
0.694
|
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
411 |
0.648
|
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
406 |
0.644
|
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
78 |
0.570
|
|
|
|
nucleoside catabolic process
|
GO:0009164 |
408 |
0.567
|
|
|
|
ras protein signal transduction
|
GO:0007265 |
73 |
0.565
|
|
|
|
regulation of nucleoside metabolic process
|
GO:0009118 |
209 |
0.552
|
|
|
|
gtp catabolic process
|
GO:0006184 |
237 |
0.551
|
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
422 |
0.544
|
|
|
|
regulation of rab gtpase activity
|
GO:0032313 |
39 |
0.524
|
|
|
|
regulation of gtp catabolic process
|
GO:0033124 |
180 |
0.523
|
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
391 |
0.512
|
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
412 |
0.452
|
|
|
|
gtp metabolic process
|
GO:0046039 |
239 |
0.451
|
|
|
|
cell projection organization
|
GO:0030030 |
252 |
0.430
|
Mouse |
|
|
regulation of purine nucleotide catabolic process
|
GO:0033121 |
205 |
0.429
|
|
|
|
nucleotide catabolic process
|
GO:0009166 |
408 |
0.427
|
|
|
|
purine nucleoside catabolic process
|
GO:0006152 |
398 |
0.399
|
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
437 |
0.394
|
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
394 |
0.391
|
|
|
|
regulation of purine nucleotide metabolic process
|
GO:1900542 |
264 |
0.372
|
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
392 |
0.369
|
|
|
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
412 |
0.364
|
|
|
|
regulation of gtpase activity
|
GO:0043087 |
180 |
0.362
|
|
|
|
regulation of small gtpase mediated signal transduction
|
GO:0051056 |
156 |
0.351
|
|
|
|
guanosine containing compound metabolic process
|
GO:1901068 |
244 |
0.347
|
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
405 |
0.336
|
|
|
|
cellular component morphogenesis
|
GO:0032989 |
314 |
0.336
|
Mouse |
|
|
positive regulation of nucleoside metabolic process
|
GO:0045979 |
186 |
0.328
|
|
|
|
nervous system development
|
GO:0007399 |
293 |
0.327
|
Mouse Fly |
|
|
regulation of nucleotide catabolic process
|
GO:0030811 |
205 |
0.305
|
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
404 |
0.281
|
|
|
|
guanosine containing compound catabolic process
|
GO:1901069 |
239 |
0.276
|
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
405 |
0.275
|
|
|
|
organophosphate catabolic process
|
GO:0046434 |
430 |
0.274
|
|
|
|
positive regulation of nucleotide catabolic process
|
GO:0030813 |
185 |
0.268
|
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
413 |
0.266
|
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
411 |
0.265
|
|
|
|
positive regulation of nucleotide metabolic process
|
GO:0045981 |
230 |
0.262
|
|
|
|
positive regulation of catabolic process
|
GO:0009896 |
310 |
0.259
|
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
412 |
0.256
|
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
391 |
0.255
|
|
|
|
regulation of nucleotide metabolic process
|
GO:0006140 |
269 |
0.252
|
|
|
|
positive regulation of gtpase activity
|
GO:0043547 |
166 |
0.243
|
|
|
|
cell projection morphogenesis
|
GO:0048858 |
129 |
0.240
|
Mouse |
|
|
rho protein signal transduction
|
GO:0007266 |
26 |
0.224
|
|
|
|
negative regulation of cellular component organization
|
GO:0051129 |
235 |
0.221
|
Fly |
|
|
regulation of ras protein signal transduction
|
GO:0046578 |
155 |
0.217
|
|
|
|
cell morphogenesis
|
GO:0000902 |
296 |
0.211
|
Mouse |
|
|
positive regulation of purine nucleotide metabolic process
|
GO:1900544 |
227 |
0.211
|
|
|
|
positive regulation of gtp catabolic process
|
GO:0033126 |
166 |
0.211
|
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
284 |
0.211
|
|
|
|
positive regulation of ras gtpase activity
|
GO:0032320 |
117 |
0.193
|
|
|
|
positive regulation of purine nucleotide catabolic process
|
GO:0033123 |
185 |
0.188
|
|
|
|
regulation of anatomical structure morphogenesis
|
GO:0022603 |
286 |
0.164
|
|
|
|
cytoplasmic transport
|
GO:0016482 |
379 |
0.153
|
|
|
|
protein ubiquitination
|
GO:0016567 |
314 |
0.138
|
Worm |
|
|
regulation of ras gtpase activity
|
GO:0032318 |
128 |
0.138
|
|
|
|
female gamete generation
|
GO:0007292 |
2 |
0.138
|
|
|
|
growth
|
GO:0040007 |
202 |
0.137
|
Fly |
|
|
generation of neurons
|
GO:0048699 |
152 |
0.124
|
Mouse |
|
|
regulation of cell cycle
|
GO:0051726 |
393 |
0.123
|
|
|
|
protein deubiquitination
|
GO:0016579 |
79 |
0.110
|
|
|
|
cellular response to endogenous stimulus
|
GO:0071495 |
336 |
0.109
|
|
|
|
neuron projection development
|
GO:0031175 |
106 |
0.105
|
Mouse |
|
|
response to oxygen containing compound
|
GO:1901700 |
369 |
0.104
|
|
|
|
positive regulation of cellular amino acid metabolic process
|
GO:0045764 |
3 |
0.102
|
|
|
|
neuron differentiation
|
GO:0030182 |
138 |
0.095
|
Mouse |
|
|
cell development
|
GO:0048468 |
328 |
0.095
|
Mouse |
|
|
chemotaxis
|
GO:0006935 |
157 |
0.094
|
Mouse |
|
|
cell morphogenesis involved in differentiation
|
GO:0000904 |
144 |
0.092
|
Mouse |
|
|
vesicle mediated transport
|
GO:0016192 |
371 |
0.089
|
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
398 |
0.088
|
|
|
|
negative regulation of developmental process
|
GO:0051093 |
247 |
0.088
|
Fly |
|
|
cellular response to dna damage stimulus
|
GO:0006974 |
379 |
0.086
|
|
|
|
oogenesis
|
GO:0048477 |
2 |
0.084
|
|
|
|
system process
|
GO:0003008 |
349 |
0.084
|
|
|
|
cellular response to oxygen containing compound
|
GO:1901701 |
276 |
0.083
|
|
|
|
microtubule cytoskeleton organization
|
GO:0000226 |
176 |
0.079
|
|
|
|
positive regulation of cellular amine metabolic process
|
GO:0033240 |
7 |
0.078
|
|
|
|
amine metabolic process
|
GO:0009308 |
44 |
0.076
|
|
|
|
regulation of protein localization
|
GO:0032880 |
296 |
0.076
|
Mouse |
|
|
chromatin organization
|
GO:0006325 |
351 |
0.075
|
|
|
|
dna repair
|
GO:0006281 |
198 |
0.074
|
|
|
|
regulation of protein kinase activity
|
GO:0045859 |
289 |
0.070
|
|
|
|
regulation of cellular component biogenesis
|
GO:0044087 |
281 |
0.069
|
Fly |
|
|
negative regulation of cellular protein metabolic process
|
GO:0032269 |
353 |
0.068
|
|
|
|
regulation of cytoskeleton organization
|
GO:0051493 |
177 |
0.067
|
Mouse |
|
|
regulation of cellular ketone metabolic process
|
GO:0010565 |
50 |
0.067
|
|
|
|
cellular ketone metabolic process
|
GO:0042180 |
80 |
0.066
|
|
|
|
neuron projection morphogenesis
|
GO:0048812 |
50 |
0.066
|
Mouse |
|
|
regulation of cell morphogenesis
|
GO:0022604 |
153 |
0.065
|
|
|
|
response to radiation
|
GO:0009314 |
151 |
0.065
|
|
|
|
regulation of immune response
|
GO:0050776 |
201 |
0.063
|
|
|
|
single organism cellular localization
|
GO:1902580 |
332 |
0.062
|
|
|
|
cell division
|
GO:0051301 |
168 |
0.062
|
|
|
|
neuromuscular junction development
|
GO:0007528 |
3 |
0.060
|
Fly |
|
|
protein localization to membrane
|
GO:0072657 |
160 |
0.059
|
|
|
|
locomotory behavior
|
GO:0007626 |
1 |
0.058
|
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
213 |
0.058
|
Worm |
|
|
ion transmembrane transport
|
GO:0034220 |
338 |
0.057
|
|
|
|
negative regulation of protein modification process
|
GO:0031400 |
200 |
0.057
|
|
|
|
apoptotic signaling pathway
|
GO:0097190 |
268 |
0.055
|
|
|
|
multicellular organismal aging
|
GO:0010259 |
3 |
0.055
|
|
|
|
blastoderm segmentation
|
GO:0007350 |
2 |
0.055
|
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
331 |
0.053
|
|
|
|
anatomical structure formation involved in morphogenesis
|
GO:0048646 |
284 |
0.052
|
|
|
|
atp catabolic process
|
GO:0006200 |
157 |
0.052
|
|
|
|
negative regulation of catalytic activity
|
GO:0043086 |
335 |
0.051
|
|
|
|
single organism membrane organization
|
GO:0044802 |
268 |
0.050
|
|
|
|
wnt signaling pathway
|
GO:0016055 |
156 |
0.047
|
|
|
|
response to organonitrogen compound
|
GO:0010243 |
156 |
0.047
|
|
|
|
cellular response to nitrogen compound
|
GO:1901699 |
144 |
0.047
|
|
|
|
central nervous system development
|
GO:0007417 |
123 |
0.047
|
Mouse |
|
|
regulation of cellular amine metabolic process
|
GO:0033238 |
11 |
0.046
|
|
|
|
determination of adult lifespan
|
GO:0008340 |
2 |
0.046
|
|
|
|
endosomal transport
|
GO:0016197 |
129 |
0.046
|
|
|
|
neuron development
|
GO:0048666 |
113 |
0.046
|
Mouse |
|
|
regulation of protein transport
|
GO:0051223 |
213 |
0.046
|
|
|
|
response to abiotic stimulus
|
GO:0009628 |
336 |
0.046
|
|
|
|
response to nitrogen compound
|
GO:1901698 |
184 |
0.045
|
|
|
|
neurogenesis
|
GO:0022008 |
169 |
0.045
|
Mouse |
|
|
protein modification by small protein removal
|
GO:0070646 |
92 |
0.045
|
|
|
|
primary neural tube formation
|
GO:0014020 |
3 |
0.045
|
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
244 |
0.045
|
|
|
|
gene silencing
|
GO:0016458 |
49 |
0.045
|
|
|
|
regulation of kinase activity
|
GO:0043549 |
314 |
0.043
|
|
|
|
regulation of cell cycle process
|
GO:0010564 |
266 |
0.043
|
|
|
|
purine ribonucleoside monophosphate metabolic process
|
GO:0009167 |
186 |
0.042
|
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
380 |
0.042
|
|
|
|
biological adhesion
|
GO:0022610 |
331 |
0.042
|
|
|
|
hindbrain development
|
GO:0030902 |
3 |
0.042
|
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
342 |
0.041
|
Worm |
|
|
purine nucleoside monophosphate metabolic process
|
GO:0009126 |
186 |
0.041
|
|
|
|
regulation of growth
|
GO:0040008 |
165 |
0.041
|
Fly |
|
|
positive regulation of organelle organization
|
GO:0010638 |
195 |
0.040
|
|
|
|
cell morphogenesis involved in neuron differentiation
|
GO:0048667 |
44 |
0.040
|
Mouse |
|
|
membrane organization
|
GO:0061024 |
292 |
0.040
|
|
|
|
cell part morphogenesis
|
GO:0032990 |
137 |
0.039
|
Mouse |
|
|
positive regulation of protein phosphorylation
|
GO:0001934 |
313 |
0.039
|
|
|
|
embryo development
|
GO:0009790 |
123 |
0.039
|
|
|
|
transmembrane transport
|
GO:0055085 |
399 |
0.038
|
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
172 |
0.038
|
|
|
|
purine nucleoside monophosphate catabolic process
|
GO:0009128 |
158 |
0.038
|
|
|
|
organelle fission
|
GO:0048285 |
149 |
0.037
|
|
|
|
regulation of protein stability
|
GO:0031647 |
87 |
0.037
|
Worm |
|
|
cell growth
|
GO:0016049 |
160 |
0.037
|
|
|
|
limbic system development
|
GO:0021761 |
3 |
0.037
|
|
|
|
endomembrane system organization
|
GO:0010256 |
196 |
0.037
|
|
|
|
cellular response to organic cyclic compound
|
GO:0071407 |
127 |
0.037
|
|
|
|
regulation of cellular response to stress
|
GO:0080135 |
244 |
0.037
|
|
|
|
regulation of cellular amino acid metabolic process
|
GO:0006521 |
6 |
0.036
|
|
|
|
protein localization to plasma membrane
|
GO:0072659 |
93 |
0.036
|
|
|
|
purine ribonucleoside monophosphate catabolic process
|
GO:0009169 |
158 |
0.036
|
|
|
|
negative regulation of cilium assembly
|
GO:1902018 |
3 |
0.036
|
|
|
|
post embryonic development
|
GO:0009791 |
2 |
0.036
|
|
|
|
cell cycle phase transition
|
GO:0044770 |
173 |
0.036
|
|
|
|
cellular amino acid metabolic process
|
GO:0006520 |
116 |
0.035
|
|
|
|
ribonucleoprotein complex subunit organization
|
GO:0071826 |
81 |
0.034
|
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
376 |
0.034
|
|
|
|
defense response
|
GO:0006952 |
315 |
0.034
|
|
|
|
taxis
|
GO:0042330 |
157 |
0.034
|
Mouse |
|
|
protein targeting
|
GO:0006605 |
187 |
0.034
|
|
|
|
negative regulation of multicellular organismal process
|
GO:0051241 |
317 |
0.034
|
Fly |
|
|
protein maturation
|
GO:0051604 |
233 |
0.033
|
|
|
|
atp metabolic process
|
GO:0046034 |
176 |
0.033
|
|
|
|
regulation of rho protein signal transduction
|
GO:0035023 |
79 |
0.033
|
|
|
|
regulation of feeding behavior
|
GO:0060259 |
3 |
0.033
|
|
|
|
regulation of canonical wnt signaling pathway
|
GO:0060828 |
88 |
0.033
|
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
242 |
0.033
|
|
|
|
positive regulation of cell division
|
GO:0051781 |
59 |
0.033
|
|
|
|
immune response
|
GO:0006955 |
307 |
0.033
|
|
|
|
negative regulation of programmed cell death
|
GO:0043069 |
321 |
0.032
|
|
|
|
negative regulation of cell death
|
GO:0060548 |
345 |
0.032
|
|
|
|
mitotic spindle elongation
|
GO:0000022 |
4 |
0.032
|
|
|
|
cell fate determination
|
GO:0001709 |
3 |
0.031
|
|
|
|
reproductive process
|
GO:0022414 |
106 |
0.031
|
Worm |
|
|
ribonucleoside monophosphate metabolic process
|
GO:0009161 |
187 |
0.031
|
|
|
|
covalent chromatin modification
|
GO:0016569 |
254 |
0.031
|
|
|
|
protein catabolic process
|
GO:0030163 |
325 |
0.030
|
Mouse |
|
|
mrna splicing via spliceosome
|
GO:0000398 |
89 |
0.030
|
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
324 |
0.030
|
|
|
|
cell projection assembly
|
GO:0030031 |
126 |
0.029
|
|
|
|
negative regulation of intracellular signal transduction
|
GO:1902532 |
183 |
0.029
|
Worm |
|
|
head development
|
GO:0060322 |
108 |
0.029
|
|
|
|
negative regulation of hydrolase activity
|
GO:0051346 |
182 |
0.029
|
|
|
|
innate immune response
|
GO:0045087 |
178 |
0.029
|
|
|
|
negative regulation of apoptotic process
|
GO:0043066 |
316 |
0.029
|
|
|
|
nerve development
|
GO:0021675 |
4 |
0.028
|
|
|
|
inositol lipid mediated signaling
|
GO:0048017 |
55 |
0.028
|
|
|
|
actin filament based process
|
GO:0030029 |
224 |
0.028
|
|
|
|
plasma membrane organization
|
GO:0007009 |
115 |
0.028
|
|
|
|
regulation of cell differentiation
|
GO:0045595 |
393 |
0.028
|
|
|
|
positive regulation of rho gtpase activity
|
GO:0032321 |
56 |
0.027
|
|
|
|
regulation of secretion by cell
|
GO:1903530 |
177 |
0.027
|
|
|
|
establishment of protein localization to membrane
|
GO:0090150 |
121 |
0.027
|
|
|
|
canonical wnt signaling pathway
|
GO:0060070 |
116 |
0.027
|
|
|
|
axon development
|
GO:0061564 |
34 |
0.027
|
Mouse |
|
|
regulation of wnt signaling pathway
|
GO:0030111 |
123 |
0.027
|
|
|
|
regulation of cell development
|
GO:0060284 |
161 |
0.027
|
|
|
|
second messenger mediated signaling
|
GO:0019932 |
78 |
0.026
|
|
|
|
phospholipid metabolic process
|
GO:0006644 |
99 |
0.026
|
|
|
|
cellular component disassembly
|
GO:0022411 |
92 |
0.026
|
|
|
|
histone modification
|
GO:0016570 |
251 |
0.026
|
|
|
|
cellular amine metabolic process
|
GO:0044106 |
41 |
0.026
|
|
|
|
histone h3 acetylation
|
GO:0043966 |
45 |
0.026
|
|
|
|
cellular protein catabolic process
|
GO:0044257 |
261 |
0.026
|
|
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
162 |
0.026
|
|
|
|
transmembrane receptor protein tyrosine kinase signaling pathway
|
GO:0007169 |
181 |
0.026
|
|
|
|
double strand break repair
|
GO:0006302 |
101 |
0.025
|
|
|
|
response to organic cyclic compound
|
GO:0014070 |
204 |
0.025
|
|
|
|
brain development
|
GO:0007420 |
97 |
0.025
|
|
|
|
nuclear division
|
GO:0000280 |
128 |
0.025
|
|
|
|
cellular response to growth factor stimulus
|
GO:0071363 |
197 |
0.025
|
|
|
|
negative regulation of phosphorus metabolic process
|
GO:0010563 |
267 |
0.025
|
Worm |
|
|
negative regulation of immune system process
|
GO:0002683 |
136 |
0.024
|
|
|
|
organ morphogenesis
|
GO:0009887 |
147 |
0.024
|
|
|
|
cilium morphogenesis
|
GO:0060271 |
75 |
0.024
|
|
|
|
lipid modification
|
GO:0030258 |
84 |
0.024
|
|
|
|
leukocyte activation
|
GO:0045321 |
164 |
0.024
|
|
|
|
regulation of cell division
|
GO:0051302 |
116 |
0.024
|
|
|
|
cellular component assembly involved in morphogenesis
|
GO:0010927 |
73 |
0.024
|
|
|
|
regulation of protein catabolic process
|
GO:0042176 |
155 |
0.024
|
Mouse |
|
|
microtubule based process
|
GO:0007017 |
210 |
0.024
|
|
|
|
protein processing
|
GO:0016485 |
226 |
0.024
|
|
|
|
protein localization to organelle
|
GO:0033365 |
280 |
0.023
|
|
|
|
negative regulation of phosphate metabolic process
|
GO:0045936 |
267 |
0.023
|
Worm |
|
|
segmentation
|
GO:0035282 |
4 |
0.023
|
|
|
|
regulation of membrane potential
|
GO:0042391 |
95 |
0.023
|
|
|
|
nucleocytoplasmic transport
|
GO:0006913 |
176 |
0.023
|
|
|
|
cellular response to organonitrogen compound
|
GO:0071417 |
124 |
0.023
|
|
|
|
regulation of cell morphogenesis involved in differentiation
|
GO:0010769 |
83 |
0.022
|
|
|
|
cilium assembly
|
GO:0042384 |
63 |
0.022
|
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
189 |
0.022
|
|
|
|
regulation of cell projection organization
|
GO:0031344 |
107 |
0.022
|
|
|
|
negative regulation of mitotic cell cycle
|
GO:0045930 |
102 |
0.022
|
|
|
|
embryonic placenta development
|
GO:0001892 |
1 |
0.022
|
|
|
|
positive regulation of apoptotic process
|
GO:0043065 |
246 |
0.022
|
|
|
|
negative regulation of protein processing
|
GO:0010955 |
142 |
0.022
|
|
|
|
glycerophospholipid metabolic process
|
GO:0006650 |
84 |
0.022
|
|
|
|
negative regulation of phosphorylation
|
GO:0042326 |
174 |
0.021
|
Worm |
|
|
nucleoside monophosphate metabolic process
|
GO:0009123 |
191 |
0.021
|
|
|
|
ribonucleoside monophosphate catabolic process
|
GO:0009158 |
158 |
0.021
|
|
|
|
metencephalon development
|
GO:0022037 |
2 |
0.021
|
|
|
|
cell substrate adhesion
|
GO:0031589 |
132 |
0.021
|
|
|
|
lipid metabolic process
|
GO:0006629 |
381 |
0.021
|
|
|
|
circadian behavior
|
GO:0048512 |
2 |
0.021
|
|
|
|
rna splicing
|
GO:0008380 |
131 |
0.021
|
|
|
|
mitotic nuclear division
|
GO:0007067 |
119 |
0.021
|
|
|
|
humoral immune response
|
GO:0006959 |
49 |
0.021
|
|
|
|
peptidyl lysine modification
|
GO:0018205 |
144 |
0.021
|
|
|
|
protein targeting to membrane
|
GO:0006612 |
42 |
0.021
|
|
|
|
autophagy
|
GO:0006914 |
88 |
0.020
|
Fly |
|
|
positive regulation of sequestering of triglyceride
|
GO:0010890 |
3 |
0.020
|
|
|
|
positive regulation of cell death
|
GO:0010942 |
263 |
0.020
|
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
206 |
0.020
|
|
|
|
cellular response to hypoxia
|
GO:0071456 |
51 |
0.020
|
|
|
|
regulation of transferase activity
|
GO:0051338 |
355 |
0.020
|
|
|
|
cellular response to abiotic stimulus
|
GO:0071214 |
117 |
0.020
|
|
|
|
enzyme linked receptor protein signaling pathway
|
GO:0007167 |
303 |
0.020
|
Fly |
|
|
cation transmembrane transport
|
GO:0098655 |
238 |
0.020
|
|
|
|
secretion
|
GO:0046903 |
254 |
0.020
|
|
|
|
intracellular protein transport
|
GO:0006886 |
270 |
0.019
|
|
|
|
regulation of proteolysis
|
GO:0030162 |
293 |
0.019
|
|
|
|
retrograde transport endosome to golgi
|
GO:0042147 |
45 |
0.019
|
|
|
|
positive regulation of immune system process
|
GO:0002684 |
283 |
0.019
|
|
|
|
response to growth factor
|
GO:0070848 |
205 |
0.019
|
|
|
|
cerebellum development
|
GO:0021549 |
2 |
0.019
|
|
|
|
positive regulation of phosphorylation
|
GO:0042327 |
394 |
0.019
|
|
|
|
photoreceptor cell differentiation
|
GO:0046530 |
2 |
0.019
|
|
|
|
regulation of secretion
|
GO:0051046 |
194 |
0.019
|
|
|
|
response to light stimulus
|
GO:0009416 |
87 |
0.019
|
|
|
|
synaptic transmission cholinergic
|
GO:0007271 |
2 |
0.019
|
|
|
|
oocyte differentiation
|
GO:0009994 |
2 |
0.019
|
|
|
|
embryonic epithelial tube formation
|
GO:0001838 |
4 |
0.018
|
|
|
|
positive regulation of developmental process
|
GO:0051094 |
314 |
0.018
|
|
|
|
mitotic cell cycle checkpoint
|
GO:0007093 |
68 |
0.018
|
|
|
|
mrna metabolic process
|
GO:0016071 |
175 |
0.018
|
|
|
|
establishment of protein localization to plasma membrane
|
GO:0090002 |
68 |
0.018
|
|
|
|
post embryonic organ development
|
GO:0048569 |
1 |
0.018
|
|
|
|
regulation of rna splicing
|
GO:0043484 |
62 |
0.018
|
|
|
|
organelle assembly
|
GO:0070925 |
176 |
0.018
|
|
|
|
negative regulation of protein complex disassembly
|
GO:0043242 |
20 |
0.018
|
|
|
|
neurological system process
|
GO:0050877 |
163 |
0.018
|
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
123 |
0.018
|
|
|
|
spinal cord development
|
GO:0021510 |
4 |
0.018
|
|
|
|
positive regulation of cell proliferation
|
GO:0008284 |
301 |
0.018
|
|
|
|
negative regulation of protein maturation
|
GO:1903318 |
142 |
0.017
|
|
|
|
cell adhesion
|
GO:0007155 |
325 |
0.017
|
|
|
|
oocyte development
|
GO:0048599 |
1 |
0.017
|
|
|
|
mitotic cell cycle process
|
GO:1903047 |
286 |
0.017
|
|
|
|
cell cell signaling
|
GO:0007267 |
155 |
0.017
|
Worm Fly |
|
|
axonogenesis
|
GO:0007409 |
31 |
0.017
|
Mouse |
|
|
nuclear transport
|
GO:0051169 |
179 |
0.017
|
|
|
|
regulation of developmental growth
|
GO:0048638 |
30 |
0.017
|
Fly |
|
|
negative regulation of mitotic cell cycle phase transition
|
GO:1901991 |
85 |
0.017
|
|
|
|
muscle contraction
|
GO:0006936 |
73 |
0.017
|
|
|
|
chordate embryonic development
|
GO:0043009 |
34 |
0.017
|
|
|
|
vasculature development
|
GO:0001944 |
181 |
0.017
|
|
|
|
negative regulation of cell cycle
|
GO:0045786 |
193 |
0.017
|
|
|
|
negative regulation of catabolic process
|
GO:0009895 |
104 |
0.017
|
Mouse |
|
|
cellular response to lipid
|
GO:0071396 |
127 |
0.017
|
|
|
|
dephosphorylation
|
GO:0016311 |
209 |
0.017
|
|
|
|
cytokinesis
|
GO:0000910 |
96 |
0.017
|
|
|
|
positive regulation of wnt signaling pathway
|
GO:0030177 |
54 |
0.017
|
|
|
|
regulation of protein processing
|
GO:0070613 |
150 |
0.016
|
|
|
|
single organism reproductive process
|
GO:0044702 |
98 |
0.016
|
|
|
|
intracellular receptor signaling pathway
|
GO:0030522 |
104 |
0.016
|
|
|
|
phosphatidylinositol metabolic process
|
GO:0046488 |
53 |
0.016
|
|
|
|
negative regulation of protein metabolic process
|
GO:0051248 |
391 |
0.016
|
Mouse |
|
|
nucleoside monophosphate catabolic process
|
GO:0009125 |
159 |
0.016
|
|
|
|
actin cytoskeleton organization
|
GO:0030036 |
207 |
0.016
|
|
|
|
morphogenesis of embryonic epithelium
|
GO:0016331 |
4 |
0.016
|
|
|
|
chemical homeostasis
|
GO:0048878 |
306 |
0.016
|
|
|
|
regulation of hormone levels
|
GO:0010817 |
125 |
0.016
|
|
|
|
tor signaling
|
GO:0031929 |
39 |
0.016
|
|
|
|
neuroblast proliferation
|
GO:0007405 |
4 |
0.016
|
|
|
|
synaptic transmission
|
GO:0007268 |
61 |
0.016
|
Worm Fly |
|
|
embryonic morphogenesis
|
GO:0048598 |
85 |
0.015
|
|
|
|
peptidyl lysine acetylation
|
GO:0018394 |
101 |
0.015
|
|
|
|
inorganic ion transmembrane transport
|
GO:0098660 |
231 |
0.015
|
|
|
|
cellular lipid metabolic process
|
GO:0044255 |
303 |
0.015
|
|
|
|
positive regulation of transport
|
GO:0051050 |
336 |
0.015
|
|
|
|
cell cell junction organization
|
GO:0045216 |
69 |
0.015
|
|
|
|
response to external biotic stimulus
|
GO:0043207 |
261 |
0.015
|
|
|
|
reactive oxygen species biosynthetic process
|
GO:1903409 |
4 |
0.015
|
|
|
|
actin filament organization
|
GO:0007015 |
128 |
0.015
|
|
|
|
microtubule polymerization or depolymerization
|
GO:0031109 |
37 |
0.015
|
|
|
|
cardiovascular system development
|
GO:0072358 |
262 |
0.015
|
|
|
|
behavior
|
GO:0007610 |
112 |
0.015
|
Worm |
|
|
establishment of nucleus localization
|
GO:0040023 |
1 |
0.015
|
|
|
|
protein k48 linked deubiquitination
|
GO:0071108 |
19 |
0.014
|
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
209 |
0.014
|
|
|
|
regulation of protein maturation
|
GO:1903317 |
150 |
0.014
|
|
|
|
positive regulation of growth
|
GO:0045927 |
58 |
0.014
|
|
|
|
protein import into nucleus
|
GO:0006606 |
104 |
0.014
|
|
|
|
regulation of synaptic vesicle transport
|
GO:1902803 |
3 |
0.014
|
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
149 |
0.014
|
|
|
|
regulation of proteasomal protein catabolic process
|
GO:0061136 |
87 |
0.014
|
|
|
|
cellular divalent inorganic cation homeostasis
|
GO:0072503 |
128 |
0.014
|
|
|
|
positive regulation of protein kinase activity
|
GO:0045860 |
190 |
0.014
|
|
|
|
regulation of cell cycle phase transition
|
GO:1901987 |
126 |
0.014
|
|
|
|
ion homeostasis
|
GO:0050801 |
230 |
0.014
|
|
|
|
ribonucleoprotein complex biogenesis
|
GO:0022613 |
116 |
0.014
|
|
|
|
regulation of dna metabolic process
|
GO:0051052 |
153 |
0.014
|
|
|
|
positive regulation of cell cycle process
|
GO:0090068 |
106 |
0.014
|
|
|
|
lymphocyte activation
|
GO:0046649 |
133 |
0.014
|
|
|
|
regulation of cilium assembly
|
GO:1902017 |
6 |
0.014
|
|
|
|
regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903050 |
91 |
0.014
|
|
|
|
positive regulation of peptidyl serine phosphorylation
|
GO:0033138 |
42 |
0.014
|
|
|
|
response to cytokine
|
GO:0034097 |
232 |
0.014
|
|
|
|
negative regulation of cell differentiation
|
GO:0045596 |
171 |
0.013
|
|
|
|
centrosome organization
|
GO:0051297 |
58 |
0.013
|
|
|
|
negative regulation of proteolysis
|
GO:0045861 |
132 |
0.013
|
|
|
|
associative learning
|
GO:0008306 |
1 |
0.013
|
|
|
|
action potential
|
GO:0001508 |
34 |
0.013
|
|
|
|
regulation of apoptotic signaling pathway
|
GO:2001233 |
175 |
0.013
|
|
|
|
inorganic cation transmembrane transport
|
GO:0098662 |
194 |
0.013
|
|
|
|
positive regulation of cell cycle
|
GO:0045787 |
140 |
0.013
|
|
|
|
regulation of cell projection assembly
|
GO:0060491 |
47 |
0.013
|
|
|
|
ribonucleoprotein complex assembly
|
GO:0022618 |
78 |
0.013
|
|
|
|
metal ion transport
|
GO:0030001 |
272 |
0.013
|
|
|
|
positive regulation of protein catabolic process
|
GO:0045732 |
75 |
0.013
|
|
|
|
positive regulation of canonical wnt signaling pathway
|
GO:0090263 |
33 |
0.013
|
|
|
|
response to nutrient levels
|
GO:0031667 |
81 |
0.013
|
|
|
|
regulation of mitotic cell cycle phase transition
|
GO:1901990 |
118 |
0.013
|
|
|
|
inner ear morphogenesis
|
GO:0042472 |
4 |
0.013
|
|
|
|
nuclear import
|
GO:0051170 |
106 |
0.013
|
|
|
|
positive regulation of immune response
|
GO:0050778 |
159 |
0.013
|
|
|
|
protein targeting to nucleus
|
GO:0044744 |
104 |
0.013
|
|
|
|
negative regulation of peptidase activity
|
GO:0010466 |
91 |
0.012
|
|
|
|
regulation of gene expression epigenetic
|
GO:0040029 |
73 |
0.012
|
|
|
|
monovalent inorganic cation transport
|
GO:0015672 |
128 |
0.012
|
|
|
|
spermatid differentiation
|
GO:0048515 |
4 |
0.012
|
|
|
|
regulation of angiogenesis
|
GO:0045765 |
92 |
0.012
|
|
|
|
chromatin modification
|
GO:0016568 |
298 |
0.012
|
|
|
|
immune response activating signal transduction
|
GO:0002757 |
90 |
0.012
|
|
|
|
establishment or maintenance of cytoskeleton polarity
|
GO:0030952 |
3 |
0.012
|
|
|
|
sodium ion transmembrane transport
|
GO:0035725 |
59 |
0.012
|
|
|
|
somatic muscle development
|
GO:0007525 |
1 |
0.012
|
|
|
|
tissue migration
|
GO:0090130 |
119 |
0.012
|
|
|
|
regulation of cellular protein catabolic process
|
GO:1903362 |
96 |
0.012
|
|
|
|
positive regulation of kinase activity
|
GO:0033674 |
204 |
0.012
|
|
|
|
regeneration
|
GO:0031099 |
4 |
0.012
|
|
|
|
somatic stem cell maintenance
|
GO:0035019 |
4 |
0.012
|
|
|
|
negative regulation of cell proliferation
|
GO:0008285 |
228 |
0.012
|
|
|
|
defense response to other organism
|
GO:0098542 |
129 |
0.012
|
|
|
|
regulation of locomotion
|
GO:0040012 |
329 |
0.012
|
|
|
|
cellular response to transforming growth factor beta stimulus
|
GO:0071560 |
94 |
0.012
|
|
|
|
rna interference
|
GO:0016246 |
4 |
0.012
|
|
|
|
negative regulation of response to external stimulus
|
GO:0032102 |
83 |
0.012
|
|
|
|
secretion by cell
|
GO:0032940 |
226 |
0.012
|
|
|
|
negative regulation of cytoskeleton organization
|
GO:0051494 |
45 |
0.012
|
|
|
|
response to biotic stimulus
|
GO:0009607 |
276 |
0.012
|
|
|
|
establishment of protein localization to endoplasmic reticulum membrane
|
GO:0097051 |
3 |
0.012
|
|
|
|
regulation of innate immune response
|
GO:0045088 |
97 |
0.012
|
|
|
|
negative regulation of defense response
|
GO:0031348 |
47 |
0.011
|
|
|
|
response to bacterium
|
GO:0009617 |
144 |
0.011
|
|
|
|
internal protein amino acid acetylation
|
GO:0006475 |
101 |
0.011
|
|
|
|
neural tube closure
|
GO:0001843 |
3 |
0.011
|
|
|
|
regulation of mrna processing
|
GO:0050684 |
48 |
0.011
|
|
|
|
epidermis morphogenesis
|
GO:0048730 |
3 |
0.011
|
|
|
|
positive regulation of programmed cell death
|
GO:0043068 |
249 |
0.011
|
|
|
|
rna splicing via transesterification reactions
|
GO:0000375 |
90 |
0.011
|
|
|
|
blood vessel development
|
GO:0001568 |
172 |
0.011
|
|
|
|
negative regulation of kinase activity
|
GO:0033673 |
106 |
0.011
|
|
|
|
cell junction assembly
|
GO:0034329 |
67 |
0.011
|
|
|
|
transcription factor import into nucleus
|
GO:0042991 |
40 |
0.011
|
|
|
|
regulation of cell adhesion
|
GO:0030155 |
166 |
0.011
|
|
|
|
neuroendocrine cell differentiation
|
GO:0061101 |
2 |
0.011
|
|
|
|
protein localization to nucleus
|
GO:0034504 |
136 |
0.011
|
|
|
|
skeletal system development
|
GO:0001501 |
79 |
0.011
|
|
|
|
neural tube formation
|
GO:0001841 |
3 |
0.011
|
|
|
|
multi organism reproductive process
|
GO:0044703 |
54 |
0.011
|
Worm |
|
|
developmental process involved in reproduction
|
GO:0003006 |
66 |
0.011
|
|
|
|
negative regulation of cell cycle process
|
GO:0010948 |
121 |
0.011
|
|
|
|
transmembrane receptor protein serine threonine kinase signaling pathway
|
GO:0007178 |
125 |
0.011
|
Fly |
|
|
regulation of intracellular transport
|
GO:0032386 |
195 |
0.011
|
|
|
|
regulation of neuron differentiation
|
GO:0045664 |
70 |
0.011
|
|
|
|
chromosome segregation
|
GO:0007059 |
114 |
0.011
|
|
|
|
signal transduction by phosphorylation
|
GO:0023014 |
297 |
0.011
|
Worm |
|
|
macromolecular complex disassembly
|
GO:0032984 |
60 |
0.011
|
|
|
|
rna processing
|
GO:0006396 |
255 |
0.011
|
|
|
|
hippocampus development
|
GO:0021766 |
1 |
0.011
|
|
|
|
negative regulation of organelle organization
|
GO:0010639 |
126 |
0.011
|
|
|
|
actin filament bundle assembly
|
GO:0051017 |
54 |
0.011
|
|
|
|
negative regulation of nervous system development
|
GO:0051961 |
28 |
0.011
|
Fly |
|
|
cellular response to peptide
|
GO:1901653 |
59 |
0.010
|
|
|
|
nucleic acid phosphodiester bond hydrolysis
|
GO:0090305 |
102 |
0.010
|
|
|
|
microtubule organizing center organization
|
GO:0031023 |
62 |
0.010
|
|
|
|
cerebellar cortex development
|
GO:0021695 |
1 |
0.010
|
|
|
|
maintenance of location
|
GO:0051235 |
112 |
0.010
|
|
|
|
histone h3 k4 demethylation trimethyl h3 k4 specific
|
GO:0034721 |
1 |
0.010
|
|
|
|
epithelial cell proliferation
|
GO:0050673 |
128 |
0.010
|
|
|
|
immune effector process
|
GO:0002252 |
159 |
0.010
|
|
|
|
establishment or maintenance of microtubule cytoskeleton polarity
|
GO:0030951 |
2 |
0.010
|
|
|
|
mitotic cell cycle
|
GO:0000278 |
326 |
0.010
|
|
|
|
regulation of protein serine threonine kinase activity
|
GO:0071900 |
179 |
0.010
|
|
|
|
embryonic organ development
|
GO:0048568 |
36 |
0.010
|
|
|
|
cell cycle checkpoint
|
GO:0000075 |
117 |
0.010
|
|
|
|
g protein coupled receptor signaling pathway
|
GO:0007186 |
207 |
0.010
|
|
|
|
embryonic forelimb morphogenesis
|
GO:0035115 |
4 |
0.010
|
|
|
|
regulation of sequence specific dna binding transcription factor activity
|
GO:0051090 |
211 |
0.010
|
|
