Homo sapiens

60 known processes

PABPC1

poly(A) binding protein, cytoplasmic 1

(Aliases: PABPL1,PABPC2,PABP1,PAB1,PABP)

PABPC1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
mrna catabolic process GO:0006402 56 1.000
nuclear transcribed mrna catabolic process deadenylation dependent decay GO:0000288 14 1.000
Yeast Mouse
mrna metabolic process GO:0016071 175 1.000
translational initiation GO:0006413 48 1.000
Yeast
translation GO:0006412 132 1.000
Yeast
rna catabolic process GO:0006401 71 1.000
nuclear transcribed mrna catabolic process GO:0000956 48 1.000
regulation of translation GO:0006417 89 1.000
Yeast
rna processing GO:0006396 255 1.000
Yeast Mouse
nuclear transcribed mrna poly a tail shortening GO:0000289 8 1.000
Yeast Mouse
regulation of translational initiation GO:0006446 24 1.000
Yeast
rna 3 end processing GO:0031123 35 1.000
Yeast Mouse
cellular macromolecule catabolic process GO:0044265 380 0.999
regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay GO:1900151 8 0.999
Yeast Mouse
posttranscriptional regulation of gene expression GO:0010608 213 0.999
Yeast
mrna processing GO:0006397 133 0.998
Yeast Mouse
mrna 3 end processing GO:0031124 24 0.998
Yeast Mouse
determination of adult lifespan GO:0008340 2 0.998
Worm
negative regulation of mrna catabolic process GO:1902373 4 0.997
regulation of mrna metabolic process GO:1903311 53 0.995
positive regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay GO:1900153 8 0.991
Mouse
negative regulation of translation GO:0017148 37 0.986
production of mirnas involved in gene silencing by mirna GO:0035196 12 0.984
nuclear transcribed mrna catabolic process no go decay GO:0070966 2 0.981
regulation of nuclear transcribed mrna poly a tail shortening GO:0060211 8 0.981
Yeast Mouse
regulation of nuclear transcribed mrna catabolic process nonsense mediated decay GO:2000622 3 0.979
rna splicing GO:0008380 131 0.972
positive regulation of translation GO:0045727 35 0.963
regulation of mrna processing GO:0050684 48 0.955
Yeast Mouse
cell development GO:0048468 328 0.952
regulation of mrna 3 end processing GO:0031440 12 0.951
Yeast Mouse
regulation of cytoplasmic mrna processing body assembly GO:0010603 5 0.941
ribonucleoprotein complex subunit organization GO:0071826 81 0.923
ncrna metabolic process GO:0034660 108 0.919
mrna cleavage involved in gene silencing by mirna GO:0035279 2 0.919
negative regulation of protein metabolic process GO:0051248 391 0.866
nucleic acid phosphodiester bond hydrolysis GO:0090305 102 0.859
Yeast
ribonucleoprotein complex assembly GO:0022618 78 0.855
negative regulation of mrna metabolic process GO:1903312 15 0.840
positive regulation of nuclear transcribed mrna poly a tail shortening GO:0060213 8 0.835
Mouse
reproductive process GO:0022414 106 0.812
Worm
organelle fission GO:0048285 149 0.805
positive regulation of mrna metabolic process GO:1903313 19 0.794
Mouse
oocyte differentiation GO:0009994 2 0.786
oogenesis GO:0048477 2 0.777
rna phosphodiester bond hydrolysis GO:0090501 35 0.773
Yeast
positive regulation of cytoplasmic mrna processing body assembly GO:0010606 4 0.772
oocyte development GO:0048599 1 0.760
regulation of mrna catabolic process GO:0061013 13 0.712
nuclear division GO:0000280 128 0.709
multicellular organismal aging GO:0010259 3 0.707
Worm
gene silencing GO:0016458 49 0.663
Mouse
positive regulation of mrna catabolic process GO:0061014 10 0.649
Mouse
regulation of growth GO:0040008 165 0.628
heart development GO:0007507 95 0.625
Zebrafish
positive regulation of mrna processing GO:0050685 17 0.608
Mouse
negative regulation of developmental process GO:0051093 247 0.597
negative regulation of translational initiation GO:0045947 7 0.574
dsrna fragmentation GO:0031050 13 0.541
nuclear transcribed mrna catabolic process nonsense mediated decay GO:0000184 23 0.539
regulation of cell differentiation GO:0045595 393 0.533
dna repair GO:0006281 198 0.529
negative regulation of cellular protein metabolic process GO:0032269 353 0.529
growth GO:0040007 202 0.525
Worm
aging GO:0007568 66 0.511
Worm
negative regulation of rna catabolic process GO:1902369 4 0.468
regulation of translation ncrna mediated GO:0045974 6 0.452
post embryonic development GO:0009791 2 0.451
Worm
cellular response to dna damage stimulus GO:0006974 379 0.448
negative regulation of translation ncrna mediated GO:0040033 6 0.419
gene silencing by rna GO:0031047 26 0.418
Mouse
gene silencing by mirna GO:0035195 23 0.414
negative regulation of translation involved in gene silencing by mirna GO:0035278 6 0.410
regionalization GO:0003002 29 0.384
cytoplasmic mrna processing body assembly GO:0033962 10 0.384
production of small rna involved in gene silencing by rna GO:0070918 13 0.380
mrna splicing via spliceosome GO:0000398 89 0.377
positive regulation of cellular component organization GO:0051130 376 0.366
positive regulation of cellular component biogenesis GO:0044089 158 0.344
regulation of rna splicing GO:0043484 62 0.335
female gamete generation GO:0007292 2 0.314
pre mirna processing GO:0031054 8 0.309
anterior posterior axis specification GO:0009948 2 0.280
cell division GO:0051301 168 0.275
positive regulation of nucleobase containing compound transport GO:0032241 1 0.254
vesicle mediated transport GO:0016192 371 0.253
Worm
ribonucleoprotein complex biogenesis GO:0022613 116 0.253
production of sirna involved in rna interference GO:0030422 3 0.252
rna phosphodiester bond hydrolysis exonucleolytic GO:0090503 14 0.250
pattern specification process GO:0007389 43 0.230
regulation of cellular component movement GO:0051270 334 0.224
cellular response to nitrogen compound GO:1901699 144 0.223
single organism reproductive process GO:0044702 98 0.217
Worm
positive regulation of organelle assembly GO:1902117 17 0.211
multicellular organism reproduction GO:0032504 42 0.206
Worm
blastoderm segmentation GO:0007350 2 0.201
positive regulation of developmental process GO:0051094 314 0.192
mrna destabilization GO:0061157 1 0.191
cellular response to dsrna GO:0071359 19 0.191
ribonucleoside triphosphate catabolic process GO:0009203 391 0.189
protein alkylation GO:0008213 74 0.182
response to nitrogen compound GO:1901698 184 0.172
anterior posterior axis specification embryo GO:0008595 2 0.165
ribonucleoside catabolic process GO:0042454 406 0.161
negative regulation of cell differentiation GO:0045596 171 0.158
postreplication repair GO:0006301 12 0.156
rna splicing via transesterification reactions GO:0000375 90 0.152
positive regulation of developmental growth GO:0048639 16 0.142
nucleoside triphosphate catabolic process GO:0009143 394 0.134
positive regulation of organelle organization GO:0010638 195 0.132
response to dsrna GO:0043331 25 0.132
reproduction GO:0000003 63 0.131
Worm
3 utr mediated mrna destabilization GO:0061158 1 0.129
purine containing compound catabolic process GO:0072523 411 0.129
posttranscriptional gene silencing by rna GO:0035194 25 0.125
mrna stabilization GO:0048255 18 0.122
purine ribonucleotide catabolic process GO:0009154 404 0.121
mitotic spindle elongation GO:0000022 4 0.120
long term synaptic potentiation GO:0060291 1 0.119
cellular macromolecular complex assembly GO:0034622 324 0.116
developmental process involved in reproduction GO:0003006 66 0.104
Worm
multicellular organismal reproductive process GO:0048609 40 0.103
Worm
stem cell development GO:0048864 69 0.097
regulation of rna stability GO:0043487 23 0.097
purine ribonucleoside triphosphate catabolic process GO:0009207 391 0.097
rna destabilization GO:0050779 1 0.093
regulation of gene expression epigenetic GO:0040029 73 0.091
spindle elongation GO:0051231 4 0.091
protein methylation GO:0006479 74 0.090
mitotic nuclear division GO:0007067 119 0.090
gamete generation GO:0007276 25 0.085
Worm
regulation of apoptotic signaling pathway GO:2001233 175 0.079
regulation of organelle assembly GO:1902115 40 0.078
purine nucleoside catabolic process GO:0006152 398 0.077
segmentation GO:0035282 4 0.077
response to other organism GO:0051707 261 0.076
purine nucleoside triphosphate catabolic process GO:0009146 392 0.075
sexual reproduction GO:0019953 37 0.075
Worm
alternative mrna splicing via spliceosome GO:0000380 27 0.073
glial cell migration GO:0008347 4 0.072
cardiovascular system development GO:0072358 262 0.069
Zebrafish
regulation of mrna splicing via spliceosome GO:0048024 32 0.069
cell projection organization GO:0030030 252 0.068
positive regulation of cell cycle process GO:0090068 106 0.065
purine ribonucleoside monophosphate metabolic process GO:0009167 186 0.064
protein complex disassembly GO:0043241 52 0.064
rna interference GO:0016246 4 0.064
regulation of developmental growth GO:0048638 30 0.062
multi organism reproductive process GO:0044703 54 0.062
Worm
regulation of cell maturation GO:1903429 3 0.062
rna phosphodiester bond hydrolysis endonucleolytic GO:0090502 15 0.061
intracellular protein transport GO:0006886 270 0.060
organelle disassembly GO:1903008 9 0.060
memory GO:0007613 3 0.059
regulation of cell cycle process GO:0010564 266 0.059
osteoblast differentiation GO:0001649 92 0.058
regulation of nuclear division GO:0051783 65 0.056
ribonucleoside triphosphate metabolic process GO:0009199 412 0.054
gastrulation GO:0007369 51 0.054
glycosyl compound catabolic process GO:1901658 413 0.054
nucleotide catabolic process GO:0009166 408 0.053
deadenylation dependent decapping of nuclear transcribed mrna GO:0000290 1 0.053
methylation GO:0032259 106 0.053
nucleoside phosphate catabolic process GO:1901292 412 0.052
wnt signaling pathway GO:0016055 156 0.052
male gamete generation GO:0048232 22 0.051
purine ribonucleoside catabolic process GO:0046130 398 0.050
negative regulation of catabolic process GO:0009895 104 0.050
purine nucleoside triphosphate metabolic process GO:0009144 412 0.049
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 89 0.049
spermatid differentiation GO:0048515 4 0.049
regulation of behavior GO:0050795 82 0.049
meiotic cell cycle GO:0051321 13 0.048
regulation of proteolysis GO:0030162 293 0.048
defense response GO:0006952 315 0.046
apoptotic signaling pathway GO:0097190 268 0.046
reproductive system development GO:0061458 56 0.045
Worm
system process GO:0003008 349 0.044
protein catabolic process GO:0030163 325 0.044
stem cell differentiation GO:0048863 93 0.044
meiotic nuclear division GO:0007126 10 0.043
organelle assembly GO:0070925 176 0.042
regulation of cell division GO:0051302 116 0.042
negative regulation of protein modification process GO:0031400 200 0.042
atp metabolic process GO:0046034 176 0.041
mrna cleavage GO:0006379 5 0.040
stem cell maintenance GO:0019827 19 0.040
positive regulation of translational initiation GO:0045948 7 0.040
long term memory GO:0007616 2 0.040
anterograde axon cargo transport GO:0008089 1 0.040
nucleoside catabolic process GO:0009164 408 0.039
regulation of alternative mrna splicing via spliceosome GO:0000381 22 0.039
positive regulation of meiosis i GO:0060903 1 0.039
regulation of synaptic plasticity GO:0048167 3 0.038
positive regulation of cysteine type endopeptidase activity GO:2001056 79 0.038
negative regulation of gene silencing by rna GO:0060967 3 0.037
establishment of vesicle localization GO:0051650 23 0.037
positive regulation of cellular catabolic process GO:0031331 284 0.036
Mouse
neurological system process GO:0050877 163 0.035
cellular lipid metabolic process GO:0044255 303 0.034
gonad development GO:0008406 34 0.033
Worm
ribosome disassembly GO:0032790 6 0.032
regulation of multicellular organism growth GO:0040014 8 0.031
regulation of system process GO:0044057 101 0.031
axis specification GO:0009798 12 0.031
regulation of reproductive process GO:2000241 15 0.031
negative regulation of striated muscle cell apoptotic process GO:0010664 2 0.030
negative regulation of defense response to virus GO:0050687 10 0.030
negative regulation of protein k63 linked ubiquitination GO:1900045 4 0.030
macromolecule methylation GO:0043414 97 0.030
cell growth GO:0016049 160 0.029
positive regulation of catabolic process GO:0009896 310 0.029
Mouse
regulation of cell cycle phase transition GO:1901987 126 0.029
regulation of meiotic cell cycle GO:0051445 4 0.028
spermatid development GO:0007286 4 0.028
regulation of multi organism process GO:0043900 157 0.028
cognition GO:0050890 43 0.028
anatomical structure formation involved in morphogenesis GO:0048646 284 0.027
cellular response to cytokine stimulus GO:0071345 181 0.026
cellular response to organic cyclic compound GO:0071407 127 0.026
receptor metabolic process GO:0043112 81 0.026
response to virus GO:0009615 126 0.026
developmental growth GO:0048589 48 0.025
regeneration GO:0031099 4 0.025
modification dependent macromolecule catabolic process GO:0043632 212 0.025
single organism cellular localization GO:1902580 332 0.025
endocytosis GO:0006897 159 0.025
Worm
regulation of cell cycle GO:0051726 393 0.024
regulation of cellular response to stress GO:0080135 244 0.024
secretion by cell GO:0032940 226 0.023
chromatin organization GO:0006325 351 0.023
regulation of striated muscle cell apoptotic process GO:0010662 3 0.023
microtubule based process GO:0007017 210 0.023
macromolecular complex disassembly GO:0032984 60 0.023
proteolysis involved in cellular protein catabolic process GO:0051603 244 0.023
dorsal ventral pattern formation GO:0009953 15 0.023
ncrna processing GO:0034470 83 0.023
regulation of oocyte development GO:0060281 1 0.023
posttranscriptional gene silencing GO:0016441 25 0.022
organophosphate catabolic process GO:0046434 430 0.022
purine ribonucleoside monophosphate catabolic process GO:0009169 158 0.022
negative regulation of hydrolase activity GO:0051346 182 0.022
regulation of defense response GO:0031347 154 0.022
purine ribonucleoside triphosphate metabolic process GO:0009205 411 0.022
negative regulation of cellular component organization GO:0051129 235 0.022
energy derivation by oxidation of organic compounds GO:0015980 43 0.021
regulation of gene silencing by rna GO:0060966 6 0.021
response to abiotic stimulus GO:0009628 336 0.021
proteasomal protein catabolic process GO:0010498 176 0.021
ribonucleotide catabolic process GO:0009261 405 0.020
regulation of endocytosis GO:0030100 72 0.020
intracellular receptor signaling pathway GO:0030522 104 0.020
embryo development ending in birth or egg hatching GO:0009792 34 0.020
Worm
anatomical structure homeostasis GO:0060249 100 0.020
neuromuscular junction development GO:0007528 3 0.020
positive regulation of multicellular organism growth GO:0040018 6 0.020
guanosine containing compound catabolic process GO:1901069 239 0.019
reproductive structure development GO:0048608 55 0.019
Worm
cellular response to endogenous stimulus GO:0071495 336 0.019
secretion GO:0046903 254 0.018
skeletal muscle tissue growth GO:0048630 2 0.018
nucleocytoplasmic transport GO:0006913 176 0.018
regulation of heart morphogenesis GO:2000826 4 0.018
positive regulation of cytoplasmic transport GO:1903651 82 0.018
intracellular steroid hormone receptor signaling pathway GO:0030518 61 0.018
regulation of wnt signaling pathway GO:0030111 123 0.018
cell projection assembly GO:0030031 126 0.017
chemical homeostasis GO:0048878 306 0.017
synaptic transmission GO:0007268 61 0.017
positive regulation of apoptotic process GO:0043065 246 0.017
cellular component disassembly GO:0022411 92 0.017
regulation of vesicle mediated transport GO:0060627 130 0.017
centrosome organization GO:0051297 58 0.017
double strand break repair GO:0006302 101 0.017
targeting of mrna for destruction involved in rna interference GO:0030423 3 0.017
positive regulation of growth GO:0045927 58 0.017
regulation of cell motility GO:2000145 299 0.017
negative regulation of multi organism process GO:0043901 92 0.016
cell substrate adhesion GO:0031589 132 0.016
negative regulation of immune system process GO:0002683 136 0.016
ossification GO:0001503 121 0.016
response to organonitrogen compound GO:0010243 156 0.016
cuticle development GO:0042335 1 0.016
regulation of response to external stimulus GO:0032101 222 0.016
positive regulation of protein oligomerization GO:0032461 17 0.016
negative regulation of protein polyubiquitination GO:1902915 4 0.015
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 181 0.015
regulation of stem cell proliferation GO:0072091 15 0.015
regulation of striated muscle tissue development GO:0016202 26 0.014
modification dependent protein catabolic process GO:0019941 209 0.014
negative regulation of proteolysis GO:0045861 132 0.014
positive regulation of locomotion GO:0040017 186 0.014
ribonucleoprotein complex disassembly GO:0032988 7 0.014
response to oxygen containing compound GO:1901700 369 0.014
negative regulation of apoptotic signaling pathway GO:2001234 97 0.014
regulation of endopeptidase activity GO:0052548 170 0.014
regulation of defense response to virus GO:0050688 33 0.014
canonical wnt signaling pathway GO:0060070 116 0.013
protein localization to membrane GO:0072657 160 0.013
regulation of protein maturation GO:1903317 150 0.013
mitotic cell cycle process GO:1903047 286 0.013
sex differentiation GO:0007548 45 0.013
Worm
meiosis i GO:0007127 4 0.013
behavior GO:0007610 112 0.013
regulation of mitochondrion organization GO:0010821 54 0.013
purine nucleoside monophosphate catabolic process GO:0009128 158 0.013
rna stabilization GO:0043489 18 0.013
striated muscle cell apoptotic process GO:0010658 3 0.013
regulation of neural precursor cell proliferation GO:2000177 4 0.013
maintenance of location GO:0051235 112 0.013
regulation of muscle cell differentiation GO:0051147 31 0.013
protein processing GO:0016485 226 0.012
regulation of cellular protein catabolic process GO:1903362 96 0.012
regulation of protein binding GO:0043393 66 0.012
cellular ion homeostasis GO:0006873 168 0.012
positive regulation of proteolysis GO:0045862 142 0.012
snrna metabolic process GO:0016073 15 0.012
cellular protein catabolic process GO:0044257 261 0.012
neuron differentiation GO:0030182 138 0.012
regulation of gene silencing GO:0060968 24 0.012
spermatogenesis GO:0007283 22 0.012
receptor mediated endocytosis GO:0006898 84 0.012
Worm
3 utr mediated mrna stabilization GO:0070935 8 0.012
tripartite regional subdivision GO:0007351 2 0.012
crd mediated mrna stabilization GO:0070934 5 0.012
meiotic chromosome segregation GO:0045132 4 0.012
defense response to other organism GO:0098542 129 0.012
regulation of response to dna damage stimulus GO:2001020 94 0.011
positive regulation of mrna 3 end processing GO:0031442 12 0.011
Mouse
female gonad development GO:0008585 10 0.011
organ morphogenesis GO:0009887 147 0.011
negative regulation of phosphorylation GO:0042326 174 0.011
developmental maturation GO:0021700 28 0.011
cellular response to nutrient levels GO:0031669 69 0.011
negative regulation of cell cycle process GO:0010948 121 0.011
response to oxygen levels GO:0070482 100 0.011
regulation of intrinsic apoptotic signaling pathway GO:2001242 72 0.011
neuron projection development GO:0031175 106 0.010
ncrna catabolic process GO:0034661 14 0.010
positive regulation of programmed cell death GO:0043068 249 0.010
negative regulation of growth GO:0045926 97 0.010
embryo development GO:0009790 123 0.010
Worm
regulation of protein stability GO:0031647 87 0.010
meiotic cell cycle process GO:1903046 8 0.010
regulation of low density lipoprotein particle receptor biosynthetic process GO:0045714 4 0.010
regulation of peptide hormone secretion GO:0090276 41 0.010
regulation of meiosis GO:0040020 3 0.010

PABPC1 disease predictions

Disease DO term ID Size Probability Func Analog Org
central nervous system disease DOID:331 186 0.192
nervous system disease DOID:863 431 0.192
neurodegenerative disease DOID:1289 102 0.176
synucleinopathy DOID:0050890 22 0.072
cancer DOID:162 167 0.026
disease of cellular proliferation DOID:14566 174 0.026
organ system cancer DOID:0050686 164 0.026
disease of metabolism DOID:0014667 295 0.011
carbohydrate metabolism disease DOID:0050013 32 0.011
acquired metabolic disease DOID:0060158 58 0.011